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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of B cell activation
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Accession:GO:0050871 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of B cell activation.
Synonyms:exact_synonym: positive regulation of B lymphocyte activation;   up regulation of B cell activation;   upregulation of B cell activation
 narrow_synonym: activation of B cell activation;   stimulation of B cell activation

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positive regulation of B cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akirin2 akirin 2 involved_in ISO (MGI:6855963|PMID:26041538) UniProt PMID:26041538 MGI:6855963 NCBI chrNW_004955411:14,600,106...14,619,374
Ensembl chrNW_004955411:14,600,106...14,619,069 		JBrowse link
G Cd81 CD81 molecule involved_in ISO (MGI:5476553|PMID:23499492) UniProt PMID:23499492 MGI:5476553 NCBI chrNW_004955422:14,155,682...14,175,181
Ensembl chrNW_004955422:14,155,682...14,175,181 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:16129705), (PMID:8566034), (PMID:9798653) MGI PMID:8566034 PMID:9798653 PMID:16129705 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
G Il6 interleukin 6 involved_in ISO (PMID:3491322) BHF-UCL PMID:3491322 NCBI chrNW_004955410:25,079,835...25,084,390 JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 involved_in ISO (PMID:20844241) BHF-UCL PMID:20844241 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710 		JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO (PMID:19734906) MGI PMID:19734906 NCBI chrNW_004955424:20,212,077...20,263,761
Ensembl chrNW_004955424:20,211,600...20,263,761 		JBrowse link
G Sh3kbp1 SH3 domain containing kinase binding protein 1 involved_in ISO (PMID:29636373) UniProt PMID:29636373 NCBI chrNW_004955509:6,157...344,930
Ensembl chrNW_004955509:4,960...345,012 		JBrowse link
G Ticam1 toll like receptor adaptor molecule 1 acts_upstream_of_or_within ISO (PMID:12855817) MGI PMID:12855817 NCBI chrNW_004955495:4,197,083...4,204,999
Ensembl chrNW_004955495:4,202,372...4,204,513 		JBrowse link
G Tlr9 toll like receptor 9 involved_in ISO (PMID:23857366) UniProt PMID:23857366 NCBI chrNW_004955532:3,828,645...3,832,699
Ensembl chrNW_004955532:3,828,775...3,832,582 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:4942267|PMID:9670042) BHF-UCL PMID:9670042 MGI:4942267 NCBI chrNW_004955406:13,477,077...13,493,309
Ensembl chrNW_004955406:13,477,077...13,493,309 		JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 involved_in ISO (MGI:3656197|PMID:16633345) UniProt PMID:16633345 MGI:3656197 NCBI chrNW_004955514:1,682,641...1,687,881 JBrowse link
B cell costimulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd320 CD320 molecule involved_in ISO (PMID:10727470) UniProt PMID:10727470 NCBI chrNW_004955563:1,084,523...1,089,395
Ensembl chrNW_004955563:1,084,474...1,093,111 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:18762567) MGI PMID:18762567 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
G Tnfrsf13c TNF receptor superfamily member 13C acts_upstream_of_or_within ISO (PMID:15240667) MGI PMID:15240667 NCBI chrNW_004955413:27,341,977...27,344,009 JBrowse link
G Tnfsf13b TNF superfamily member 13b acts_upstream_of_or_within ISO (PMID:15240667) MGI PMID:15240667 NCBI chrNW_004955404:3,536,041...3,573,242
Ensembl chrNW_004955404:3,536,868...3,569,750 		JBrowse link
positive regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp11c ATPase phospholipid transporting 11C involved_in ISO (MGI:5002406|PMID:21423173) UniProt PMID:21423173 MGI:5002406 NCBI chrNW_004955489:5,394,553...5,567,295
Ensembl chrNW_004955489:5,394,357...5,567,405 		JBrowse link
G Bad BCL2 associated agonist of cell death acts_upstream_of_or_within ISO (PMID:12431371) MGI PMID:12431371 NCBI chrNW_004955422:20,795,585...20,809,039
Ensembl chrNW_004955422:20,795,676...20,809,245 		JBrowse link
G Il2rg interleukin 2 receptor subunit gamma acts_upstream_of_or_within ISO (PMID:9252128)
(PMID:23918385)		 MGI PMID:9252128 PMID:23918385 NCBI chrNW_004955475:10,676,592...10,680,565
Ensembl chrNW_004955475:10,676,870...10,680,517 		JBrowse link
G Il7 interleukin 7 acts_upstream_of_or_within ISO (PMID:16797412) MGI PMID:16797412 NCBI chrNW_004955444:2,365,077...2,400,953 JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D acts_upstream_of_or_within ISO (PMID:10704460), (PMID:9620849) MGI PMID:9620849 PMID:10704460 NCBI chrNW_004955453:2,938,659...3,037,211
Ensembl chrNW_004955453:2,938,659...3,037,211 		JBrowse link
G Mmp14 matrix metallopeptidase 14 involved_in ISO (MGI:5013661|PMID:21572390) UniProt PMID:21572390 MGI:5013661 NCBI chrNW_004955409:37,438,924...37,448,704
Ensembl chrNW_004955409:37,440,541...37,448,437 		JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISO (MGI:3818191|PMID:19015308) UniProt PMID:19015308 MGI:3818191 NCBI chrNW_004955458:1,733,799...1,785,591
Ensembl chrNW_004955458:1,733,883...1,784,182 		JBrowse link
G Pcid2 PCI domain containing 2 involved_in ISO (MGI:4839685|PMID:20870947) UniProt PMID:20870947 MGI:4839685 NCBI chrNW_004955404:618,092...639,424
Ensembl chrNW_004955404:618,092...639,704 		JBrowse link
G Ppp2r3c protein phosphatase 2 regulatory subunit B''gamma acts_upstream_of_or_within ISO (PMID:16129705) MGI PMID:16129705 NCBI chrNW_004955409:25,920,973...25,943,985 JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO (PMID:33951726) UniProt PMID:33951726 NCBI chrNW_004955422:873,735...886,560
Ensembl chrNW_004955422:873,735...886,560 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO (PMID:10979977) MGI PMID:10979977 NCBI chrNW_004955451:16,305,363...16,319,219
Ensembl chrNW_004955451:16,305,363...16,318,534 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B acts_upstream_of_or_within ISO (PMID:10979977) MGI PMID:10979977 NCBI chrNW_004955451:16,253,645...16,295,337
Ensembl chrNW_004955451:16,255,398...16,272,214 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in
acts_upstream_of_or_within		 ISO (PMID:18369315)
(PMID:7477353)
(PMID:7477352)		 CACAO
MGI		 PMID:7477352 PMID:7477353 PMID:18369315 NCBI chrNW_004955515:1,328,793...1,400,206
Ensembl chrNW_004955515:1,328,630...1,380,581 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO (PMID:11460154) UniProt PMID:11460154 NCBI chrNW_004955455:3,037,885...3,041,827 JBrowse link
positive regulation of B cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within ISO (PMID:14607964) MGI PMID:14607964 NCBI chrNW_004955445:12,696,096...12,717,488
Ensembl chrNW_004955445:12,696,096...12,717,488 		JBrowse link
G Atad5 ATPase family AAA domain containing 5 acts_upstream_of_or_within ISO (PMID:25404367) MGI PMID:25404367 NCBI chrNW_004955481:6,986,128...7,031,113
Ensembl chrNW_004955481:6,986,502...7,030,742 		JBrowse link
G Bcl2 BCL2 apoptosis regulator involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chrNW_004955402:46,911,125...47,084,214
Ensembl chrNW_004955402:46,916,266...47,084,485 		JBrowse link
G Bcl6 BCL6 transcription repressor acts_upstream_of_or_within ISO (PMID:9171827) MGI PMID:9171827 NCBI chrNW_004955420:19,998,960...20,021,200
Ensembl chrNW_004955420:19,998,742...20,022,259 		JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger involved_in ISO (MGI:3615850|PMID:15964995) HGNC-UCL PMID:15964995 MGI:3615850 NCBI chrNW_004955429:6,548,586...6,553,730
Ensembl chrNW_004955429:6,547,731...6,558,105 		JBrowse link
G Btk Bruton tyrosine kinase ISO RGD PMID:28352114 RGD:151665126 NCBI chrNW_004955503:7,483,819...7,515,085
Ensembl chrNW_004955503:7,482,793...7,515,120 		JBrowse link
G Card11 caspase recruitment domain family member 11 acts_upstream_of_or_within ISO (PMID:12867038) MGI PMID:12867038 NCBI chrNW_004955460:12,368,987...12,487,675
Ensembl chrNW_004955460:12,368,918...12,490,041 		JBrowse link
G Cd320 CD320 molecule involved_in ISO (PMID:10727470) UniProt PMID:10727470 NCBI chrNW_004955563:1,084,523...1,089,395
Ensembl chrNW_004955563:1,084,474...1,093,111 		JBrowse link
G Cd38 CD38 molecule involved_in
acts_upstream_of_or_within		 ISO (PMID:17875758)
(PMID:8666928)		 UniProt
MGI		 PMID:8666928 PMID:17875758 NCBI chrNW_004955480:8,177,178...8,218,483
Ensembl chrNW_004955480:8,178,473...8,217,643 		JBrowse link
G Cd40 CD40 molecule acts_upstream_of_or_within ISO (PMID:10979977), (PMID:11894097), (PMID:14607964), (PMID:8666928), (PMID:8920854)
(PMID:15963492)		 MGI PMID:8666928 PMID:8920854 PMID:10979977 PMID:11894097 PMID:14607964 More... NCBI chrNW_004955445:11,191,817...11,202,156
Ensembl chrNW_004955445:11,190,603...11,202,093 		JBrowse link
G Cd40lg CD40 ligand ISO RGD PMID:18384807 RGD:2313415 NCBI chrNW_004955489:8,465,571...8,477,714
Ensembl chrNW_004955489:8,465,164...8,477,746 		JBrowse link
G Cd74 CD74 molecule involved_in ISO (PMID:12782713) BHF-UCL PMID:12782713 NCBI chrNW_004955415:4,129,151...4,138,336
Ensembl chrNW_004955415:4,129,254...4,137,826 		JBrowse link
G Cd81 CD81 molecule involved_in ISO (PMID:10400713) AgBase PMID:10400713 NCBI chrNW_004955422:14,155,682...14,175,181
Ensembl chrNW_004955422:14,155,682...14,175,181 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A acts_upstream_of_or_within ISO (PMID:12970760) MGI PMID:12970760 NCBI chrNW_004955437:6,254,638...6,261,278
Ensembl chrNW_004955437:6,254,309...6,261,479 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit acts_upstream_of_or_within ISO (PMID:15963492) MGI PMID:15963492 NCBI chrNW_004955545:1,065,457...1,077,056
Ensembl chrNW_004955545:1,065,457...1,077,526 		JBrowse link
G Clcf1 cardiotrophin like cytokine factor 1 involved_in ISO (MGI:3777853|PMID:12023368) BHF-UCL PMID:12023368 MGI:3777853 NCBI chrNW_004955422:18,097,779...18,108,628
Ensembl chrNW_004955422:18,097,779...18,108,628 		JBrowse link
G Ephb2 EPH receptor B2 involved_in ISO (PMID:24803541) ARUK-UCL PMID:24803541 NCBI chrNW_004955452:2,844,713...2,986,790
Ensembl chrNW_004955452:2,844,713...2,980,445 		JBrowse link
G Gpr183 G protein-coupled receptor 183 involved_in ISO (PMID:21673108)
(MGI:5430842|PMID:21673108)		 UniProt PMID:21673108 MGI:5430842 NCBI chrNW_004955404:11,264,954...11,277,531
Ensembl chrNW_004955404:11,264,954...11,277,531 		JBrowse link
G Il13 interleukin 13 ISO requires CD40 antigen RGD PMID:10331006 PMID:11573960 RGD:61509 RGD:633067 NCBI chrNW_004955408:4,046,406...4,049,795 JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 ISO requires CD40 antigen RGD PMID:11573960 RGD:633067 NCBI chrNW_004955534:1,157,758...1,205,158
Ensembl chrNW_004955534:1,160,340...1,204,911 		JBrowse link
G Il2 interleukin 2 acts_upstream_of_or_within ISO (PMID:9184696) MGI PMID:9184696 NCBI chrNW_004955428:18,163,010...18,168,157
Ensembl chrNW_004955428:18,162,467...18,168,265 		JBrowse link
G Il21 interleukin 21 acts_upstream_of_or_within ISO (PMID:17673207) MGI PMID:17673207 NCBI chrNW_004955428:18,057,096...18,065,492
Ensembl chrNW_004955428:18,057,096...18,065,492 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:10979977), (PMID:14607964) MGI PMID:10979977 PMID:14607964 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
G Il5 interleukin 5 ISO RGD PMID:10529595 RGD:2303750 NCBI chrNW_004955408:3,937,128...3,951,784
Ensembl chrNW_004955408:3,937,894...3,939,358 		JBrowse link
G Il7 interleukin 7 acts_upstream_of_or_within ISO (PMID:12970760)
(PMID:7671324)		 MGI PMID:7671324 PMID:12970760 NCBI chrNW_004955444:2,365,077...2,400,953 JBrowse link
G Irs2 insulin receptor substrate 2 involved_in ISO (MGI:4456946|PMID:15572028) BHF-UCL PMID:15572028 MGI:4456946 NCBI chrNW_004955404:2,531,484...2,555,383
Ensembl chrNW_004955404:2,531,484...2,555,689 		JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISO (MGI:3829850|PMID:18955699) UniProt PMID:18955699 MGI:3829850 NCBI chrNW_004955418:22,537,388...22,701,434
Ensembl chrNW_004955418:22,537,285...22,701,434 		JBrowse link
G Mif macrophage migration inhibitory factor involved_in ISO (PMID:12782713) BHF-UCL PMID:12782713 NCBI chrNW_004955455:8,367,566...8,368,460
Ensembl chrNW_004955455:8,367,566...8,368,460 		JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chrNW_004955458:1,733,799...1,785,591
Ensembl chrNW_004955458:1,733,883...1,784,182 		JBrowse link
G Nfatc2 nuclear factor of activated T cells 2 involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chrNW_004955445:7,035,876...7,153,199
Ensembl chrNW_004955445:7,035,876...7,153,237 		JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO (PMID:19734906) MGI PMID:19734906 NCBI chrNW_004955424:20,212,077...20,263,761
Ensembl chrNW_004955424:20,211,600...20,263,761 		JBrowse link
G Prlr prolactin receptor ISO RGD PMID:8650199 PMID:9447986 RGD:151665811 RGD:151667430 NCBI chrNW_004955426:20,161,406...20,326,688
Ensembl chrNW_004955426:20,168,830...20,326,840 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C involved_in
acts_upstream_of_or_within		 ISO (PMID:1793833)
(PMID:8666928)
(PMID:8566034), (PMID:9015183), (PMID:9254656)		 UniProt
MGI		 PMID:1793833 PMID:8566034 PMID:8666928 PMID:9015183 PMID:9254656 NCBI chrNW_004955406:35,005,577...35,127,395
Ensembl chrNW_004955406:35,005,214...35,129,552 		JBrowse link
G Sash3 SAM and SH3 domain containing 3 acts_upstream_of_or_within ISO (PMID:16227612) MGI PMID:16227612 NCBI chrNW_004955473:5,224,635...5,237,066
Ensembl chrNW_004955473:5,222,408...5,237,260 		JBrowse link
G Slc39a10 solute carrier family 39 member 10 acts_upstream_of_or_within ISO (PMID:25074919) MGI PMID:25074919 NCBI chrNW_004955403:4,426,538...4,479,693 JBrowse link
G Tcf3 transcription factor 3 involved_in ISO (PMID:11509675) UniProt PMID:11509675 NCBI chrNW_004955495:6,337,311...6,365,193
Ensembl chrNW_004955495:6,337,870...6,367,487 		JBrowse link
G Tfrc transferrin receptor involved_in ISO (PMID:26642240)
(MGI:5775517|PMID:26642240)		 UniProt PMID:26642240 MGI:5775517 NCBI chrNW_004955420:12,348,392...12,372,714
Ensembl chrNW_004955420:12,348,821...12,372,691 		JBrowse link
G Ticam1 toll like receptor adaptor molecule 1 acts_upstream_of_or_within ISO (PMID:12855817) MGI PMID:12855817 NCBI chrNW_004955495:4,197,083...4,204,999
Ensembl chrNW_004955495:4,202,372...4,204,513 		JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (MGI:3531416|PMID:12447442) BHF-UCL PMID:12447442 MGI:3531416 NCBI chrNW_004955412:27,303,548...27,315,031
Ensembl chrNW_004955412:27,312,489...27,315,031 		JBrowse link
G Tlr4 toll like receptor 4 acts_upstream_of_or_within ISO (PMID:10549626) MGI PMID:10549626 NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135 		JBrowse link
G Tlr9 toll like receptor 9 involved_in ISO (PMID:23857366) UniProt PMID:23857366 NCBI chrNW_004955532:3,828,645...3,832,699
Ensembl chrNW_004955532:3,828,775...3,832,582 		JBrowse link
G Tnfrsf13c TNF receptor superfamily member 13C acts_upstream_of_or_within ISO (PMID:15240667) MGI PMID:15240667 NCBI chrNW_004955413:27,341,977...27,344,009 JBrowse link
G Tnfrsf4 TNF receptor superfamily member 4 involved_in ISO (MGI:74350|PMID:7749983) BHF-UCL PMID:7749983 MGI:74350 NCBI chrNW_004955486:9,565,424...9,569,836
Ensembl chrNW_004955486:9,567,220...9,569,676 		JBrowse link
G Tnfsf13b TNF superfamily member 13b involved_in
acts_upstream_of_or_within		 ISO (PMID:17499850)
(PMID:15240667)		 AgBase
MGI		 PMID:15240667 PMID:17499850 NCBI chrNW_004955404:3,536,041...3,573,242
Ensembl chrNW_004955404:3,536,868...3,569,750 		JBrowse link
G Vav3 vav guanine nucleotide exchange factor 3 involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chrNW_004955435:11,326,910...11,599,043
Ensembl chrNW_004955435:11,326,910...11,599,043 		JBrowse link
G Wnt3a Wnt family member 3A acts_upstream_of_or_within ISO (PMID:10933391) MGI PMID:10933391 NCBI chrNW_004955581:351,375...382,541
Ensembl chrNW_004955581:350,889...382,541 		JBrowse link
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:3763508|PMID:12496423) BHF-UCL PMID:12496423 MGI:3763508 NCBI chrNW_004955406:13,477,077...13,493,309
Ensembl chrNW_004955406:13,477,077...13,493,309 		JBrowse link
positive regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Exosc3 exosome component 3 acts_upstream_of_or_within ISO (PMID:21255825) MGI PMID:21255825 NCBI chrNW_004955419:28,683,896...28,692,006
Ensembl chrNW_004955419:28,683,896...28,693,395 		JBrowse link
G Exosc6 exosome component 6 acts_upstream_of_or_within ISO (PMID:21255825) MGI PMID:21255825 NCBI chrNW_004955484:3,088,133...3,089,551
Ensembl chrNW_004955484:3,088,624...3,089,472 		JBrowse link
G Hmces 5-hydroxymethylcytosine binding, ES cell specific involved_in ISO (MGI:6393148|PMID:31806351) UniProt PMID:31806351 MGI:6393148 NCBI chrNW_004955429:13,616,647...13,638,657
Ensembl chrNW_004955429:13,616,647...13,661,389 		JBrowse link
G Kmt5b lysine methyltransferase 5B involved_in ISO (MGI:6370097|PMID:28114273) UniProt PMID:28114273 MGI:6370097 NCBI chrNW_004955422:17,626,606...17,684,890
Ensembl chrNW_004955422:17,647,530...17,682,132 		JBrowse link
G Kmt5c lysine methyltransferase 5C involved_in ISO (MGI:6370097|PMID:28114273) UniProt PMID:28114273 MGI:6370097 NCBI chrNW_004955567:895,334...901,240
Ensembl chrNW_004955567:894,608...900,578 		JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chrNW_004955486:2,191,903...2,197,193
Ensembl chrNW_004955486:2,191,903...2,198,538 		JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (MGI:4821506|PMID:20671152) UniProt PMID:20671152 MGI:4821506 NCBI chrNW_004955491:8,177,422...8,219,764
Ensembl chrNW_004955491:8,177,422...8,219,766 		JBrowse link
G Rif1 replication timing regulatory factor 1 involved_in ISO (MGI:5468036|PMID:23306439), (MGI:5476381|PMID:23333305), (MGI:5490831|PMID:23333306) UniProt PMID:23306439 PMID:23333305 PMID:23333306 MGI:5468036 MGI:5476381 MGI:5490831 NCBI chrNW_004955440:16,977,710...17,047,809
Ensembl chrNW_004955440:16,979,042...17,041,748 		JBrowse link
G Shld1 shieldin complex subunit 1 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chrNW_004955415:16,180,074...16,282,937
Ensembl chrNW_004955415:16,180,051...16,280,864 		JBrowse link
G Shld2 shieldin complex subunit 2 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chrNW_004955510:6,021,477...6,114,745
Ensembl chrNW_004955510:6,075,510...6,114,898 		JBrowse link
G Tfrc transferrin receptor involved_in ISO (PMID:26642240) UniProt PMID:26642240 NCBI chrNW_004955420:12,348,392...12,372,714
Ensembl chrNW_004955420:12,348,821...12,372,691 		JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 involved_in ISO (PMID:23760478)
(MGI:3041657|PMID:15077110), (MGI:3046005|PMID:15159415)
(PMID:23345425)		 UniProt PMID:15077110 PMID:15159415 PMID:23345425 PMID:23760478 MGI:3041657 MGI:3046005 NCBI chrNW_004955416:9,962,736...10,035,433
Ensembl chrNW_004955416:9,962,897...10,035,278 		JBrowse link
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chrNW_004955421:3,890,291...3,936,892
Ensembl chrNW_004955421:3,890,306...3,936,526 		JBrowse link
G Msh2 mutS homolog 2 involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chrNW_004955441:14,188,315...14,247,608
Ensembl chrNW_004955441:14,187,805...14,247,698 		JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 acts_upstream_of_or_within ISO (PMID:23241889) MGI PMID:23241889 NCBI chrNW_004955514:1,084,522...1,162,624
Ensembl chrNW_004955514:1,069,085...1,162,624 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chrNW_004955460:13,762,854...13,791,462 JBrowse link
G Tgfb1 transforming growth factor beta 1 acts_upstream_of_or_within ISO (PMID:14988498) MGI PMID:14988498 NCBI chrNW_004955555:274,405...288,441
Ensembl chrNW_004955555:270,652...288,441 		JBrowse link
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcf1 cardiotrophin like cytokine factor 1 involved_in ISO (MGI:3777853|PMID:12023368) BHF-UCL PMID:12023368 MGI:3777853 NCBI chrNW_004955422:18,097,779...18,108,628
Ensembl chrNW_004955422:18,097,779...18,108,628 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:14988498) MGI PMID:14988498 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
G Stat6 signal transducer and activator of transcription 6 acts_upstream_of_or_within ISO (PMID:10490661) MGI PMID:10490661 NCBI chrNW_004955458:4,833,417...4,847,956
Ensembl chrNW_004955458:4,833,515...4,843,273 		JBrowse link
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family AAA domain containing 5 acts_upstream_of_or_within ISO (PMID:25404367) MGI PMID:25404367 NCBI chrNW_004955481:6,986,128...7,031,113
Ensembl chrNW_004955481:6,986,502...7,030,742 		JBrowse link
G Cd28 CD28 molecule acts_upstream_of_or_within ISO (PMID:7688139) MGI PMID:7688139 NCBI chrNW_004955457:11,159,769...11,253,099
Ensembl chrNW_004955457:11,162,282...11,192,991 		JBrowse link
G Cd40 CD40 molecule acts_upstream_of_or_within ISO (PMID:12882831) MGI PMID:12882831 NCBI chrNW_004955445:11,191,817...11,202,156
Ensembl chrNW_004955445:11,190,603...11,202,093 		JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:12882831) MGI PMID:12882831 NCBI chrNW_004955458:14,643,333...14,648,020
Ensembl chrNW_004955458:14,643,313...14,648,045 		JBrowse link
G Il2 interleukin 2 acts_upstream_of_or_within ISO (PMID:1830926) MGI PMID:1830926 NCBI chrNW_004955428:18,163,010...18,168,157
Ensembl chrNW_004955428:18,162,467...18,168,265 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:12882831), (PMID:14988498) MGI PMID:12882831 PMID:14988498 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
G Mlh1 mutL homolog 1 involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chrNW_004955421:3,890,291...3,936,892
Ensembl chrNW_004955421:3,890,306...3,936,526 		JBrowse link
G Msh2 mutS homolog 2 involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chrNW_004955441:14,188,315...14,247,608
Ensembl chrNW_004955441:14,187,805...14,247,698 		JBrowse link
G Pagr1 PAXIP1 associated glutamate rich protein 1 involved_in ISO (MGI:5752090|PMID:26744420) UniProt PMID:26744420 MGI:5752090 NCBI chrNW_004955493:7,142,048...7,144,836
Ensembl chrNW_004955493:7,142,272...7,144,389 		JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (MGI:5752090|PMID:26744420) UniProt PMID:26744420 MGI:5752090 NCBI chrNW_004955491:8,177,422...8,219,764
Ensembl chrNW_004955491:8,177,422...8,219,766 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chrNW_004955460:13,762,854...13,791,462 JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of_or_within ISO (PMID:9015183) MGI PMID:9015183 NCBI chrNW_004955406:35,005,577...35,127,395
Ensembl chrNW_004955406:35,005,214...35,129,552 		JBrowse link
G Tbx21 T-box transcription factor 21 acts_upstream_of_or_within ISO (PMID:12882831) MGI PMID:12882831 NCBI chrNW_004955451:13,315,237...13,317,888
Ensembl chrNW_004955451:13,315,859...13,325,937 		JBrowse link
positive regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10 interleukin 10 acts_upstream_of ISO (PMID:22962438) ARUK-UCL PMID:22962438 NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779 		JBrowse link
G Il2 interleukin 2 acts_upstream_of ISO (PMID:22962438) ARUK-UCL PMID:22962438 NCBI chrNW_004955428:18,163,010...18,168,157
Ensembl chrNW_004955428:18,162,467...18,168,265 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO (PMID:11460154) UniProt PMID:11460154 NCBI chrNW_004955455:3,037,885...3,041,827 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12362
    immune system process 1980
      leukocyte activation 888
        lymphocyte activation 720
          B cell activation 256
            positive regulation of B cell activation 86
              B cell costimulation 4
              positive regulation of B cell differentiation + 16
              positive regulation of B cell proliferation 46
              positive regulation of isotype switching + 29
Path 2
Term Annotations click to browse term
  biological_process 12362
    biological regulation 8888
      regulation of biological process 8622
        regulation of multicellular organismal process 2854
          positive regulation of multicellular organismal process 1632
            positive regulation of cell activation 328
              positive regulation of leukocyte activation 306
                positive regulation of lymphocyte activation 275
                  positive regulation of B cell activation 86
                    B cell costimulation 4
                    positive regulation of B cell differentiation + 16
                    positive regulation of B cell proliferation 46
                    positive regulation of isotype switching + 29
paths to the root