Exosc3 (exosome component 3) - Rat Genome Database

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Gene: Exosc3 (exosome component 3) Chinchilla lanigera
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Symbol: Exosc3
Name: exosome component 3
RGD ID: 8733326
Description: ENCODES a protein that exhibits RNA exonuclease activity (ortholog); INVOLVED IN CUT catabolic process (ortholog); DNA deamination (ortholog); isotype switching (ortholog); ASSOCIATED WITH acromesomelic dysplasia, Maroteaux type (ortholog); congenital myopathy (ortholog); distal arthrogryposis type 1A (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic exosome (RNase complex) (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: exosome complex component RRP40
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541928,683,896 - 28,693,395 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541928,683,896 - 28,692,006 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Exosc3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541928,683,896 - 28,693,395 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541928,683,896 - 28,692,006 (+)NCBIChiLan1.0ChiLan1.0
EXOSC3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38937,779,714 - 37,785,092 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl937,759,234 - 37,832,117 (-)EnsemblGRCh38hg38GRCh38
GRCh37937,779,711 - 37,785,089 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36937,770,308 - 37,775,067 (-)NCBINCBI36Build 36hg18NCBI36
Build 34937,770,307 - 37,775,065NCBI
Celera937,713,503 - 37,718,262 (-)NCBICelera
Cytogenetic Map9p13.2NCBI
HuRef937,732,052 - 37,737,430 (-)NCBIHuRef
CHM1_1937,781,396 - 37,786,774 (-)NCBICHM1_1
T2T-CHM13v2.0937,803,445 - 37,808,823 (-)NCBIT2T-CHM13v2.0
Exosc3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39445,316,613 - 45,320,616 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl445,316,613 - 45,342,732 (-)EnsemblGRCm39 Ensembl
GRCm38445,316,613 - 45,320,616 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl445,316,613 - 45,342,732 (-)EnsemblGRCm38mm10GRCm38
MGSCv37445,329,501 - 45,333,475 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36445,337,729 - 45,341,703 (-)NCBIMGSCv36mm8
Celera445,338,021 - 45,341,971 (-)NCBICelera
Cytogenetic Map4B1NCBI
cM Map423.84NCBI
Exosc3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8564,369,495 - 64,374,711 (-)NCBIGRCr8
mRatBN7.2559,573,849 - 59,579,065 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl559,573,886 - 59,579,060 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx561,548,206 - 61,553,432 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0563,367,709 - 63,372,935 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0563,336,918 - 63,342,144 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0560,866,498 - 60,871,734 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl560,868,502 - 60,871,705 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0565,375,248 - 65,380,463 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4561,880,622 - 61,883,825 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1561,878,837 - 61,884,005 (-)NCBI
Celera558,144,199 - 58,147,390 (-)NCBICelera
Cytogenetic Map5q22NCBI
EXOSC3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21186,802,391 - 86,829,345 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1986,808,332 - 86,835,286 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0937,611,173 - 37,634,869 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1938,552,659 - 38,558,075 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl938,552,659 - 38,558,078 (-)Ensemblpanpan1.1panPan2
EXOSC3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11154,072,993 - 54,079,024 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1154,073,313 - 54,078,598 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1152,499,195 - 52,504,935 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01155,182,436 - 55,188,175 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1155,182,171 - 55,217,148 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11153,680,587 - 53,686,326 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01153,710,218 - 53,715,957 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01154,406,491 - 54,412,231 (-)NCBIUU_Cfam_GSD_1.0
Exosc3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947169,033,275 - 169,038,601 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365245,581,090 - 5,586,128 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365245,580,855 - 5,586,170 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EXOSC3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1238,536,345 - 238,541,333 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11238,536,341 - 238,541,756 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21266,471,332 - 266,476,724 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EXOSC3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11242,798,609 - 42,819,431 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1242,799,067 - 42,803,471 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603839,866,661 - 39,887,819 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Exosc3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249301,393,087 - 1,398,347 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249301,393,087 - 1,403,483 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000024544   ⟹   ENSCLAP00000024309
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541928,683,896 - 28,693,395 (+)Ensembl
RefSeq Acc Id: XM_005382860   ⟹   XP_005382917
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541928,683,896 - 28,692,006 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005382917 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000024309
  ENSCLAP00000024309.1
RefSeq Acc Id: XP_005382917   ⟸   XM_005382860
- UniProtKB: A0A8C2W2Q7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000024309   ⟸   ENSCLAT00000024544

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000016689 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000024544 ENTREZGENE
  ENSCLAT00000024544.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.100 UniProtKB/TrEMBL
  2.40.50.140 UniProtKB/TrEMBL
  3.30.1370.10 UniProtKB/TrEMBL
InterPro Exosome_RNA_bind1/RRP40/RRP4 UniProtKB/TrEMBL
  KH_dom_type_1 UniProtKB/TrEMBL
  KH_dom_type_1_sf UniProtKB/TrEMBL
  NA-bd_OB-fold UniProtKB/TrEMBL
  RRP40_KH-I UniProtKB/TrEMBL
  RRP40_N UniProtKB/TrEMBL
  Rrp40_S1 UniProtKB/TrEMBL
NCBI Gene Exosc3 ENTREZGENE
PANTHER EXOSOME COMPLEX COMPONENT RRP40 UniProtKB/TrEMBL
  PTHR21321 UniProtKB/TrEMBL
Pfam KH_6 UniProtKB/TrEMBL
  RRP40_N_mamm UniProtKB/TrEMBL
  RRP40_S1 UniProtKB/TrEMBL
Superfamily-SCOP Ribosomal L27 protein-like UniProtKB/TrEMBL
  SSF50249 UniProtKB/TrEMBL
  SSF54791 UniProtKB/TrEMBL
UniProt A0A8C2W2Q7 ENTREZGENE, UniProtKB/TrEMBL