Tcf3 (transcription factor 3) - Rat Genome Database

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Gene: Tcf3 (transcription factor 3) Chinchilla lanigera
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Symbol: Tcf3
Name: transcription factor 3
RGD ID: 8767519
Description: ENCODES a protein that exhibits bHLH transcription factor binding (ortholog); chromatin binding (ortholog); cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN B cell lineage commitment (ortholog); cell development (ortholog); chromatin remodeling (ortholog); ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); agammaglobulinemia (ortholog); Agammaglobulinemia 8 (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: transcription factor E2-alpha
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554956,337,870 - 6,367,487 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554956,337,311 - 6,365,193 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Tcf3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554956,337,870 - 6,367,487 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554956,337,311 - 6,365,193 (+)NCBIChiLan1.0ChiLan1.0
TCF3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38191,609,292 - 1,652,615 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl191,609,291 - 1,652,615 (-)EnsemblGRCh38hg38GRCh38
GRCh37191,609,291 - 1,652,614 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36191,560,293 - 1,601,277 (-)NCBINCBI36Build 36hg18NCBI36
Build 34191,560,294 - 1,601,277NCBI
Celera191,544,148 - 1,586,451 (-)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef191,383,232 - 1,423,075 (-)NCBIHuRef
CHM1_1191,609,123 - 1,649,881 (-)NCBICHM1_1
T2T-CHM13v2.0191,580,117 - 1,623,781 (-)NCBIT2T-CHM13v2.0
Tcf3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391080,245,375 - 80,269,814 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1080,245,348 - 80,269,481 (-)EnsemblGRCm39 Ensembl
GRCm381080,409,541 - 80,433,976 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1080,409,514 - 80,433,647 (-)EnsemblGRCm38mm10GRCm38
MGSCv371079,871,910 - 79,896,398 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361079,812,723 - 79,836,736 (-)NCBIMGSCv36mm8
Celera1081,426,533 - 81,451,021 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Tcf3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr879,931,251 - 9,952,994 (+)NCBIGRCr8
mRatBN7.279,280,571 - 9,302,315 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl79,280,571 - 9,302,314 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx712,157,100 - 12,178,811 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0714,032,424 - 14,054,151 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0711,900,016 - 11,921,838 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0712,146,642 - 12,168,400 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl712,144,162 - 12,168,410 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0712,316,323 - 12,338,455 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4710,791,311 - 10,813,613 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1710,791,310 - 10,813,165 (+)NCBI
Celera77,461,200 - 7,481,028 (+)NCBICelera
Cytogenetic Map7q11NCBI
TCF3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2205,974,390 - 6,017,153 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1195,205,287 - 5,248,110 (-)NCBINHGRI_mPanPan1
PanPan1.1191,582,297 - 1,622,025 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl191,582,297 - 1,622,025 (-)Ensemblpanpan1.1panPan2
TCF3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12057,255,091 - 57,284,223 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2057,254,384 - 57,283,981 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2057,045,568 - 57,076,063 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02057,984,288 - 58,014,495 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2057,985,608 - 58,014,477 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12057,041,346 - 57,071,536 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02057,520,665 - 57,550,910 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02057,722,526 - 57,752,778 (+)NCBIUU_Cfam_GSD_1.0
Tcf3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118216,921,770 - 216,949,966 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936588884,789 - 912,753 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936588884,817 - 913,052 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TCF3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl276,859,089 - 76,898,351 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1276,859,079 - 76,906,275 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2278,181,360 - 78,220,554 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TCF3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.161,393,147 - 1,440,515 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl61,393,107 - 1,440,479 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660817,409,480 - 7,459,296 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tcf3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248287,090,605 - 7,121,428 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248287,090,562 - 7,119,970 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000017662   ⟹   ENSCLAP00000017490
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554956,337,870 - 6,367,487 (+)Ensembl
Ensembl Acc Id: ENSCLAT00000017663   ⟹   ENSCLAP00000017491
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554956,337,870 - 6,367,487 (+)Ensembl
Ensembl Acc Id: ENSCLAT00000017664   ⟹   ENSCLAP00000017492
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554956,337,870 - 6,367,487 (+)Ensembl
Ensembl Acc Id: ENSCLAT00000017665   ⟹   ENSCLAP00000017493
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554956,337,870 - 6,363,974 (+)Ensembl
RefSeq Acc Id: XM_005405953   ⟹   XP_005406010
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554956,337,312 - 6,364,584 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005405954   ⟹   XP_005406011
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554956,337,312 - 6,364,584 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005405955   ⟹   XP_005406012
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554956,337,312 - 6,364,584 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005405956   ⟹   XP_005406013
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554956,337,311 - 6,364,070 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013505276   ⟹   XP_013360730
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554956,337,314 - 6,365,193 (+)NCBI
Sequence:
RefSeq Acc Id: XP_005406013   ⟸   XM_005405956
- Peptide Label: isoform X5
- UniProtKB: A0A8C2VQU5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005406012   ⟸   XM_005405955
- Peptide Label: isoform X4
- UniProtKB: A0A8C2VU00 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005406010   ⟸   XM_005405953
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VLV6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005406011   ⟸   XM_005405954
- Peptide Label: isoform X3
- UniProtKB: A0A8C2VU00 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013360730   ⟸   XM_013505276
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSCLAP00000017490   ⟸   ENSCLAT00000017662
Ensembl Acc Id: ENSCLAP00000017491   ⟸   ENSCLAT00000017663
Ensembl Acc Id: ENSCLAP00000017492   ⟸   ENSCLAT00000017664
Ensembl Acc Id: ENSCLAP00000017493   ⟸   ENSCLAT00000017665
Protein Domains
bHLH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000012013 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000017662 ENTREZGENE
  ENSCLAT00000017662.1 UniProtKB/TrEMBL
  ENSCLAT00000017663 ENTREZGENE
  ENSCLAT00000017663.1 UniProtKB/TrEMBL
  ENSCLAT00000017664.1 UniProtKB/TrEMBL
  ENSCLAT00000017665 ENTREZGENE
  ENSCLAT00000017665.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.280.10 UniProtKB/TrEMBL
InterPro bHLH_dom UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/TrEMBL
  NeuroDiff_E-box_TFs UniProtKB/TrEMBL
NCBI Gene Tcf3 ENTREZGENE
PANTHER BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR UniProtKB/TrEMBL
  TRANSCRIPTION FACTOR E2-ALPHA UniProtKB/TrEMBL
Pfam HLH UniProtKB/TrEMBL
PROSITE BHLH UniProtKB/TrEMBL
SMART HLH UniProtKB/TrEMBL
Superfamily-SCOP SSF47459 UniProtKB/TrEMBL
UniProt A0A8C2VLV6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VNU3_CHILA UniProtKB/TrEMBL
  A0A8C2VQU5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VU00 ENTREZGENE, UniProtKB/TrEMBL