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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of osteoclast differentiation
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Accession:GO:0045671 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of osteoclast differentiation.
Synonyms:exact_synonym: down regulation of osteoclast differentiation;   downregulation of osteoclast differentiation
 narrow_synonym: inhibition of osteoclast differentiation


show annotations for term's descendants           Sort by:
negative regulation of osteoclast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calca calcitonin-related polypeptide alpha involved_in ISO (PMID:10822112) RGD PMID:10822112 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 involved_in ISO
ISS		 (PMID:21403648)
GO_REF:0000024		 RGD
UniProt		 PMID:21403648 GO_REF:0000024 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 acts_upstream_of_or_within ISO (PMID:25490771) RGD PMID:25490771 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Clec2d C-type lectin domain family 2, member D acts_upstream_of_or_within ISO (PMID:12374791) RGD PMID:12374791 NCBI chr 4:162,216,052...162,239,530
Ensembl chr 4:162,216,572...162,239,527 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2148567|MGI:3041864 (PMID:15866165)		 Ensembl
RGD		 PMID:15866165 GO_REF:0000107 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Erfe erythroferrone acts_upstream_of ISS
ISO		 GO_REF:0000024
(PMID:34002695)		 UniProt
RGD		 PMID:34002695 GO_REF:0000024 NCBI chr 9:91,956,971...91,964,846
Ensembl chr 9:91,956,977...91,964,846 		JBrowse link
G Fbn1 fibrillin 1 involved_in ISO (PMID:24039232) RGD PMID:24039232 NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889 		JBrowse link
G Fstl3 follistatin like 3 involved_in ISO
IEA		 (PMID:15574124)
GO_REF:0000107		 RGD
Ensembl		 PMID:15574124 GO_REF:0000107 NCBI chr 7:9,923,574...9,929,223
Ensembl chr 7:9,923,576...9,939,639 		JBrowse link
G Gpr137 G protein-coupled receptor 137 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:204,129,636...204,132,622
Ensembl chr 1:204,129,636...204,133,082 		JBrowse link
G Gpr137b G protein-coupled receptor 137B involved_in IBA
ISO		 GO_REF:0000033
(PMID:31173907)		 GO_Central
RGD		 PMID:31173907 GO_REF:0000033 NCBI chr17:86,003,635...86,041,841
Ensembl chr17:85,966,921...86,041,835 		JBrowse link
G Gpr55 G protein-coupled receptor 55 involved_in ISO (PMID:19805329) RGD PMID:19805329 NCBI chr 9:86,584,906...86,640,601
Ensembl chr 9:86,590,885...86,640,613 		JBrowse link
G Iapp islet amyloid polypeptide acts_upstream_of_or_within ISO MGI:1346858|MGI:2656235 (PMID:14970190) RGD PMID:14970190 NCBI chr 4:175,237,107...175,244,373
Ensembl chr 4:175,237,115...175,242,920 		JBrowse link
G Ifnb1 interferon beta 1 acts_upstream_of_or_within ISO (PMID:17442941) RGD PMID:17442941 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:17442941) RGD PMID:17442941 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:12941478), (PMID:17442941) RGD PMID:12941478 PMID:17442941 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase type II B acts_upstream_of_or_within ISO MGI:102469|MGI:1100089 (PMID:21982707) RGD PMID:21982707 NCBI chr19:25,920,189...26,670,085
Ensembl chr19:25,925,358...26,280,634 		JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2386884 (PMID:12161749)		 Ensembl
RGD		 PMID:12161749 GO_REF:0000107 NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746 		JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:18802077) RGD PMID:18802077 NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660 		JBrowse link
G Lrrc17 leucine rich repeat containing 17 involved_in ISO (PMID:19336404) RGD PMID:19336404 NCBI chr 4:13,501,428...13,531,845
Ensembl chr 4:13,501,436...13,531,845 		JBrowse link
G Mafb MAF bZIP transcription factor B involved_in ISS
ISO		 GO_REF:0000024
(PMID:19440205)		 UniProt
RGD		 PMID:19440205 GO_REF:0000024 NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031 		JBrowse link
G Nf1 neurofibromin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1100089|MGI:1339753|MGI:97583 (PMID:17053831)		 Ensembl
RGD		 PMID:17053831 GO_REF:0000107 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
G Pias3 protein inhibitor of activated STAT, 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:17442941)		 Ensembl
RGD		 PMID:17442941 GO_REF:0000107 NCBI chr 2:184,232,546...184,241,455
Ensembl chr 2:184,232,571...184,241,480 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:97306 (PMID:17053831)		 Ensembl
RGD		 PMID:17053831 GO_REF:0000107 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Pilrb1 paired immunoglobin-like type 2 receptor beta 1 involved_in ISO (PMID:18802077) RGD PMID:18802077 NCBI chr12:18,516,161...18,525,375
Ensembl chr12:18,516,156...18,525,346 		JBrowse link
G Pirb paired Ig-like receptor B involved_in ISO (PMID:18802077) RGD PMID:18802077 NCBI chr 1:65,499,195...65,506,666
Ensembl chr 1:65,499,195...65,506,666 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 acts_upstream_of_or_within
involved_in		 IMP
ISO
IEA		 MGI:3045799 (PMID:14976225)
GO_REF:0000107		 RGD
Ensembl		 PMID:14976225 PMID:17540629 GO_REF:0000107, RGD:4107086 NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286 		JBrowse link
G Tcta T-cell leukemia translocation altered involved_in ISO (PMID:19560569) RGD PMID:19560569 NCBI chr 8:108,988,588...108,992,324
Ensembl chr 8:108,988,590...108,991,564 		JBrowse link
G Tmem178a transmembrane protein 178A involved_in ISS
ISO
IBA
IEA		 GO_REF:0000024
(PMID:26644563)
GO_REF:0000033
GO_REF:0000107		 UniProt
RGD
GO_Central
Ensembl		 PMID:26644563 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:14,004,629...14,063,677
Ensembl chr 6:14,004,630...14,063,549 		JBrowse link
G Tnfaip6 TNF alpha induced protein 6 involved_in ISO (PMID:18586671) RGD PMID:18586671 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B acts_upstream_of_or_within
involved_in		 ISO (PMID:29415886)
(PMID:9168977)		 RGD PMID:9168977 PMID:29415886 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538 		JBrowse link
G Tob2 transducer of ERBB2, 2 acts_upstream_of_or_within ISO MGI:3789484 (PMID:18358842) RGD PMID:18358842 NCBI chr 7:113,362,703...113,371,423
Ensembl chr 7:113,361,148...113,372,688 		JBrowse link
G Ubash3b ubiquitin associated and SH3 domain containing, B acts_upstream_of_or_within ISO (PMID:23149425) RGD PMID:23149425 NCBI chr 8:41,385,419...41,532,248
Ensembl chr 8:41,388,341...41,532,201 		JBrowse link
negative regulation of osteoclast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cldn18 claudin 18 acts_upstream_of_or_within ISO MGI:5007067 (PMID:22437732) RGD PMID:22437732 NCBI chr 8:100,246,499...100,265,797
Ensembl chr 8:100,247,633...100,273,351 		JBrowse link
G Fbn1 fibrillin 1 involved_in ISO (PMID:24039232) RGD PMID:24039232 NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889 		JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 involved_in ISO (PMID:29149593) RGD PMID:29149593 NCBI chr 2:170,149,706...170,311,536
Ensembl chr 2:170,149,694...170,309,941 		JBrowse link
G Tjp2 tight junction protein 2 acts_upstream_of_or_within ISO (PMID:22437732) RGD PMID:22437732 NCBI chr 1:221,709,745...221,838,291
Ensembl chr 1:221,709,745...221,838,295 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      negative regulation of cellular process 5536
        negative regulation of cell differentiation 797
          negative regulation of myeloid cell differentiation 98
            negative regulation of myeloid leukocyte differentiation 59
              negative regulation of osteoclast differentiation 35
                negative regulation of osteoclast development 4
Path 2
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      cellular developmental process 4782
        cell differentiation 4781
          cell development 3326
            regulation of cell development 975
              regulation of hemopoiesis 445
                negative regulation of hemopoiesis 134
                  negative regulation of leukocyte differentiation 126
                    negative regulation of myeloid leukocyte differentiation 59
                      negative regulation of osteoclast differentiation 35
                        negative regulation of osteoclast development 4
paths to the root