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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of leukocyte differentiation
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Accession:GO:1902106 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte differentiation.
Synonyms:exact_synonym: down regulation of immune cell differentiation;   down regulation of leucocyte differentiation;   down regulation of leukocyte differentiation;   downregulation of immune cell differentiation;   downregulation of leucocyte differentiation;   downregulation of leukocyte differentiation;   negative regulation of immune cell differentiation;   negative regulation of leucocyte differentiation
 narrow_synonym: inhibition of immune cell differentiation;   inhibition of leucocyte differentiation;   inhibition of leukocyte differentiation



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negative regulation of alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli3 GLI family zinc finger 3 involved_in ISO (MGI:4355451|PMID:19667090) RGD PMID:19667090 MGI:4355451 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712
JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in ISO (MGI:3836494|PMID:19109233) RGD PMID:19109233 MGI:3836494 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532
JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:1888832|PMID:10981962)
Ensembl
RGD
PMID:10981962 GO_REF:0000107 MGI:1888832 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
negative regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flt3 Fms related receptor tyrosine kinase 3 acts_upstream_of_or_within ISO (MGI:3623701|PMID:16618805) RGD PMID:16618805 MGI:3623701 NCBI chr12:7,623,658...7,699,474
Ensembl chr12:7,623,930...7,699,474
JBrowse link
G Hmgb3 high mobility group box 3 acts_upstream_of_or_within ISO (MGI:2670545|PMID:12714519) RGD PMID:12714519 MGI:2670545 NCBI chr  X:149,296,309...149,301,294
Ensembl chr  X:149,296,375...149,301,292
JBrowse link
G Id2 inhibitor of DNA binding 2 acts_upstream_of_or_within ISO MGI:2384134 (MGI:3805135|PMID:18523151) RGD PMID:18523151 MGI:3805135 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in ISO
IEA
(PMID:18941195)
(MGI:3814493|PMID:18941195)
GO_REF:0000107
RGD
Ensembl
PMID:18941195 GO_REF:0000107 MGI:3814493 NCBI chr16:68,575,763...68,613,905
Ensembl chr16:68,575,763...68,614,286
JBrowse link
negative regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbfb core-binding factor subunit beta involved_in ISO (MGI:3772948|PMID:18258917) RGD PMID:18258917 MGI:3772948 NCBI chr19:33,049,162...33,092,752
Ensembl chr19:33,049,172...33,092,751
JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:22473704) RGD PMID:22473704 NCBI chr12:5,973,062...5,978,565 JBrowse link
G Runx1 RUNX family transcription factor 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3772948|PMID:18258917)
UniProt
RGD
PMID:18258917 GO_REF:0000024 MGI:3772948 NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542
JBrowse link
G Runx3 RUNX family transcription factor 3 involved_in ISO (MGI:3772948|PMID:18258917) RGD PMID:18258917 MGI:3772948 NCBI chr 5:147,393,926...147,419,161
Ensembl chr 5:147,360,994...147,419,156
JBrowse link
negative regulation of CD8-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Socs1 suppressor of cytokine signaling 1 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:6140589|PMID:24880459)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:24880459 GO_REF:0000024 GO_REF:0000107 MGI:6140589 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B involved_in ISO (MGI:5446998|PMID:22730529), (MGI:6140589|PMID:24880459) RGD PMID:22730529 PMID:24880459 MGI:5446998 MGI:6140589 NCBI chr 2:174,795,831...174,811,980
Ensembl chr 2:174,797,453...174,814,236
JBrowse link
negative regulation of cytotoxic T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:16493035) RGD PMID:16493035 NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660
JBrowse link
negative regulation of dendritic cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tmem176a transmembrane protein 176A involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:4835631|PMID:20501748)
RGD PMID:20501748 PMID:21873635 MGI:4835631, RGD:13792537 NCBI chr 4:77,774,940...77,778,620
Ensembl chr 4:77,774,843...77,778,620
JBrowse link
G Tmem176b transmembrane protein 176B involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:4835631|PMID:20501748)
RGD PMID:20501748 PMID:21873635 MGI:4835631, RGD:13792537 NCBI chr 4:77,766,928...77,774,740
Ensembl chr 4:77,766,928...77,774,384
JBrowse link
G Zbtb46 zinc finger and BTB domain containing 46 acts_upstream_of_or_within ISO MGI:5320483 (MGI:5320487|PMID:22615127) RGD PMID:22615127 MGI:5320487 NCBI chr 3:168,497,294...168,567,799
Ensembl chr 3:168,499,583...168,568,782
JBrowse link
negative regulation of granulocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISO
ISS
(PMID:10961870)
GO_REF:0000024
RGD
UniProt
PMID:10961870 GO_REF:0000024 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G C1qc complement C1q C chain involved_in ISO
IEA
(PMID:10961870)
GO_REF:0000107
RGD
Ensembl
PMID:10961870 GO_REF:0000107 NCBI chr 5:149,127,424...149,130,732
Ensembl chr 5:149,127,415...149,131,017
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:4837548|PMID:21029969)
UniProt
RGD
PMID:21029969 GO_REF:0000024 MGI:4837548 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992
JBrowse link
G Cul4a cullin 4A acts_upstream_of_or_within ISO (MGI:3691926|PMID:12393421) RGD PMID:12393421 MGI:3691926 NCBI chr16:76,385,298...76,422,316
Ensembl chr16:76,384,546...76,422,330
JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D acts_upstream_of_or_within ISO MGI:2386884 (MGI:1266928|PMID:9620849) RGD PMID:9620849 MGI:1266928 NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746
JBrowse link
G Prdm16 PR/SET domain 16 involved_in ISO (PMID:12816872) RGD PMID:12816872 NCBI chr 5:164,879,864...165,203,986
Ensembl chr 5:164,880,587...165,203,601
JBrowse link
G Rara retinoic acid receptor, alpha involved_in ISO (PMID:19917671) RGD PMID:19917671 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Runx1 RUNX family transcription factor 1 involved_in ISO (PMID:9199349) RGD PMID:9199349 NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542
JBrowse link
G Zbtb46 zinc finger and BTB domain containing 46 acts_upstream_of_or_within ISO MGI:5320483 (MGI:5320487|PMID:22615127) RGD PMID:22615127 MGI:5320487 NCBI chr 3:168,497,294...168,567,799
Ensembl chr 3:168,499,583...168,568,782
JBrowse link
negative regulation of immature T cell proliferation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:12421925)
Ensembl
UniProt
RGD
PMID:12421925 GO_REF:0000024 GO_REF:0000107 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A involved_in ISO (MGI:3615850|PMID:15964995) RGD PMID:15964995 MGI:3615850 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3695084|PMID:16230479)
GO_REF:0000107
RGD
Ensembl
PMID:16230479 GO_REF:0000107 MGI:3695084 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in ISO (MGI:3836494|PMID:19109233) RGD PMID:19109233 MGI:3836494 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532
JBrowse link
G Tmem131l transmembrane 131 like involved_in ISO (PMID:23690469) RGD PMID:23690469 NCBI chr 2:169,257,659...169,391,773
Ensembl chr 2:169,258,289...169,391,711
JBrowse link
negative regulation of lymphocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo7 F-box protein 7 acts_upstream_of_or_within ISO MGI:4434927|MGI:95407 (MGI:5317390|PMID:21652635) RGD PMID:21652635 MGI:5317390 NCBI chr 7:17,809,224...17,837,549
Ensembl chr 7:17,809,231...17,837,530
JBrowse link
negative regulation of macrophage differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISO
ISS
(PMID:10961870)
GO_REF:0000024
RGD
UniProt
PMID:10961870 GO_REF:0000024 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G C1qc complement C1q C chain involved_in ISO
IEA
(PMID:10961870)
GO_REF:0000107
RGD
Ensembl
PMID:10961870 GO_REF:0000107 NCBI chr 5:149,127,424...149,130,732
Ensembl chr 5:149,127,415...149,131,017
JBrowse link
G Gata2 GATA binding protein 2 acts_upstream_of_or_within ISO (MGI:3769271|PMID:16254139) RGD PMID:16254139 MGI:3769271 NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761
JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:3629372|PMID:16705167)
UniProt
RGD
PMID:16705167 GO_REF:0000024 MGI:3629372 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627
JBrowse link
G Thoc5 THO complex 5 acts_upstream_of_or_within ISO (MGI:1349551|PMID:10597251) RGD PMID:10597251 MGI:1349551 NCBI chr14:79,758,805...79,792,718
Ensembl chr14:79,758,917...79,792,718
JBrowse link
G Zbtb46 zinc finger and BTB domain containing 46 acts_upstream_of_or_within ISO MGI:5320483 (MGI:5320487|PMID:22615127) RGD PMID:22615127 MGI:5320487 NCBI chr 3:168,497,294...168,567,799
Ensembl chr 3:168,499,583...168,568,782
JBrowse link
negative regulation of mast cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zfpm1 zinc finger protein, multitype 1 involved_in ISO (MGI:3773481|PMID:18063754) RGD PMID:18063754 MGI:3773481 NCBI chr19:50,334,352...50,391,029
Ensembl chr19:50,334,682...50,390,591
JBrowse link
negative regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgl2 fibrinogen-like 2 acts_upstream_of_or_within ISO MGI:3582343 (MGI:6188369|PMID:29341118) RGD PMID:29341118 MGI:6188369 NCBI chr 4:13,710,566...13,716,207
Ensembl chr 4:13,710,575...13,716,207
JBrowse link
G Ifnl1 interferon, lambda 1 involved_in ISO (PMID:19346497) RGD PMID:19346497 NCBI chr 1:83,798,651...83,800,297 JBrowse link
negative regulation of monocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apcs amyloid P component, serum involved_in IEA
ISO
GO_REF:0000107
(PMID:14607961)
Ensembl
RGD
PMID:14607961 GO_REF:0000107 NCBI chr13:85,373,338...85,374,134
Ensembl chr13:85,373,220...85,374,298
JBrowse link
G Cdk6 cyclin-dependent kinase 6 involved_in ISO (PMID:26542173) RGD PMID:26542173 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
JBrowse link
G Gpr68 G protein-coupled receptor 68 acts_upstream_of_or_within ISO MGI:3849457 (MGI:3848292|PMID:19479052) RGD PMID:19479052 MGI:3848292 NCBI chr 6:120,135,620...120,166,089
Ensembl chr 6:120,135,436...120,166,089
JBrowse link
G Hoxa7 homeobox A7 involved_in ISO
IEA
(PMID:14704364)
GO_REF:0000107
RGD
Ensembl
PMID:14704364 GO_REF:0000107 NCBI chr 4:81,315,730...81,317,629
Ensembl chr 4:81,314,625...81,317,659
JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2386884 (MGI:1266928|PMID:9620849)
Ensembl
RGD
PMID:9620849 GO_REF:0000107 MGI:1266928 NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO
ISS
(PMID:9924025)
GO_REF:0000024
RGD
UniProt
PMID:9924025 GO_REF:0000024 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Zbtb46 zinc finger and BTB domain containing 46 acts_upstream_of_or_within ISO MGI:5320483 (MGI:5320487|PMID:22615127) RGD PMID:22615127 MGI:5320487 NCBI chr 3:168,497,294...168,567,799
Ensembl chr 3:168,499,583...168,568,782
JBrowse link
negative regulation of myeloid leukocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (MGI:2152233|PMID:11672542) RGD PMID:11672542 MGI:2152233 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 IDA RGD PMID:7737424 RGD:2299083 NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 IDA RGD PMID:7737424 RGD:2299083 NCBI chr10:78,898,097...78,903,600
Ensembl chr10:78,897,770...78,903,538
JBrowse link
negative regulation of natural killer cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pglyrp1 peptidoglycan recognition protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2670590 (MGI:5297102|PMID:20709292)
Ensembl
RGD
PMID:20709292 GO_REF:0000107 MGI:5297102 NCBI chr 1:78,531,815...78,537,001
Ensembl chr 1:78,531,815...78,537,001
JBrowse link
G Pglyrp2 peptidoglycan recognition protein 2 acts_upstream_of_or_within ISO MGI:5297105 (MGI:5297102|PMID:20709292) RGD PMID:20709292 MGI:5297102 NCBI chr 7:11,418,674...11,432,162
Ensembl chr 7:11,418,880...11,427,773
JBrowse link
G Pglyrp3 peptidoglycan recognition protein 3 acts_upstream_of_or_within ISO MGI:5297106 (MGI:5297102|PMID:20709292) RGD PMID:20709292 MGI:5297102 NCBI chr 2:177,479,693...177,490,867
Ensembl chr 2:176,855,732...176,874,162
Ensembl chr 2:176,855,732...176,874,162
JBrowse link
G Pglyrp4 peptidoglycan recognition protein 4 acts_upstream_of_or_within ISO MGI:5297107 (MGI:5297102|PMID:20709292) RGD PMID:20709292 MGI:5297102 NCBI chr 2:176,202,654...176,322,859
Ensembl chr 2:176,218,519...176,242,251
JBrowse link
negative regulation of neutrophil differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Inpp5d inositol polyphosphate-5-phosphatase D involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2386884 (MGI:1266928|PMID:9620849)
Ensembl
RGD
PMID:9620849 GO_REF:0000107 MGI:1266928 NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746
JBrowse link
G Trib1 tribbles pseudokinase 1 involved_in ISO (MGI:5488531|PMID:23515163) RGD PMID:23515163 MGI:5488531 NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731
JBrowse link
negative regulation of osteoclast development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cldn18 claudin 18 acts_upstream_of_or_within ISO MGI:5007067 (MGI:5489769|PMID:22437732) RGD PMID:22437732 MGI:5489769 NCBI chr 8:100,246,499...100,265,797
Ensembl chr 8:100,247,633...100,273,351
JBrowse link
G Fbn1 fibrillin 1 involved_in ISO (PMID:24039232)
(MGI:5795811|PMID:24039232)
RGD PMID:24039232 MGI:5795811 NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889
JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 involved_in ISO (PMID:29149593)
(MGI:6106664|PMID:29149593)
RGD PMID:29149593 MGI:6106664 NCBI chr 2:170,150,552...170,310,698
Ensembl chr 2:170,149,694...170,309,941
JBrowse link
G Tjp2 tight junction protein 2 acts_upstream_of_or_within ISO (MGI:5489769|PMID:22437732) RGD PMID:22437732 MGI:5489769 NCBI chr 1:221,709,745...221,838,383
Ensembl chr 1:221,709,745...221,838,295
JBrowse link
negative regulation of osteoclast differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calca calcitonin-related polypeptide alpha involved_in ISO (PMID:10822112) RGD PMID:10822112 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 involved_in ISO
ISS
(PMID:21403648)
GO_REF:0000024
RGD
UniProt
PMID:21403648 GO_REF:0000024 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 acts_upstream_of_or_within ISO (MGI:5691608|PMID:25490771) RGD PMID:25490771 MGI:5691608 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992
JBrowse link
G Clec2d C-type lectin domain family 2, member D acts_upstream_of_or_within ISO (MGI:2446956|PMID:12374791) RGD PMID:12374791 MGI:2446956 NCBI chr 4:162,216,052...162,239,530
Ensembl chr 4:162,216,572...162,239,527
JBrowse link
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2148567|MGI:3041864 (MGI:3578468|PMID:15866165)
Ensembl
RGD
PMID:15866165 GO_REF:0000107 MGI:3578468 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Fbn1 fibrillin 1 involved_in ISO (PMID:24039232)
(MGI:5795811|PMID:24039232)
RGD PMID:24039232 MGI:5795811 NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889
JBrowse link
G Fstl3 follistatin like 3 involved_in ISO (PMID:15574124) RGD PMID:15574124 NCBI chr 7:9,924,670...9,929,195
Ensembl chr 7:9,923,576...9,939,639
JBrowse link
G Gpr137 G protein-coupled receptor 137 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:204,129,636...204,132,622
Ensembl chr 1:204,129,636...204,133,082
JBrowse link
G Gpr137b G protein-coupled receptor 137B involved_in IBA
ISO
PMID:21873635
(MGI:6362357|PMID:31173907)
RGD PMID:31173907 PMID:21873635 MGI:6362357, RGD:13792537 NCBI chr17:86,003,630...86,041,841
Ensembl chr17:85,966,921...86,041,835
JBrowse link
G Gpr55 G protein-coupled receptor 55 involved_in ISO (PMID:19805329) RGD PMID:19805329 NCBI chr 9:86,584,906...86,640,601
Ensembl chr 9:86,590,885...86,640,613
JBrowse link
G Ifnb1 interferon beta 1 acts_upstream_of_or_within ISO (MGI:3836131|PMID:17442941) RGD PMID:17442941 MGI:3836131 NCBI chr 5:103,020,969...103,021,523
Ensembl chr 5:103,020,969...103,021,523
JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (MGI:3836131|PMID:17442941) RGD PMID:17442941 MGI:3836131 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (MGI:2675763|PMID:12941478), (MGI:3836131|PMID:17442941) RGD PMID:12941478 PMID:17442941 MGI:2675763 MGI:3836131 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase type II B acts_upstream_of_or_within ISO MGI:102469|MGI:1100089 (MGI:5295788|PMID:21982707) RGD PMID:21982707 MGI:5295788 NCBI chr19:25,920,189...26,670,085
Ensembl chr19:25,925,358...26,280,634
JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2386884 (MGI:2386137|PMID:12161749)
Ensembl
RGD
PMID:12161749 GO_REF:0000107 MGI:2386137 NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746
JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:18802077) RGD PMID:18802077 NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660
JBrowse link
G Lrrc17 leucine rich repeat containing 17 involved_in ISO (MGI:3850892|PMID:19336404) RGD PMID:19336404 MGI:3850892 NCBI chr 4:13,501,428...13,531,845
Ensembl chr 4:13,501,436...13,531,845
JBrowse link
G Mafb MAF bZIP transcription factor B involved_in ISS
ISO
GO_REF:0000024
(MGI:3849531|PMID:19440205)
UniProt
RGD
PMID:19440205 GO_REF:0000024 MGI:3849531 NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031
JBrowse link
G Nf1 neurofibromin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1100089|MGI:1339753|MGI:97583 (MGI:3689489|PMID:17053831)
Ensembl
RGD
PMID:17053831 GO_REF:0000107 MGI:3689489 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658
JBrowse link
G Pias3 protein inhibitor of activated STAT, 3 acts_upstream_of_or_within ISO (MGI:3836131|PMID:17442941) RGD PMID:17442941 MGI:3836131 NCBI chr 2:184,232,546...184,241,455
Ensembl chr 2:184,232,571...184,241,480
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:97306 (MGI:3689489|PMID:17053831)
Ensembl
RGD
PMID:17053831 GO_REF:0000107 MGI:3689489 NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Pirb paired Ig-like receptor B involved_in ISO (PMID:18802077) RGD PMID:18802077
G Sfrp1 secreted frizzled-related protein 1 acts_upstream_of_or_within
involved_in
IMP
ISO
IEA
MGI:3045799 (MGI:3040721|PMID:14976225)
GO_REF:0000107
RGD
Ensembl
PMID:14976225 PMID:17540629 GO_REF:0000107 MGI:3040721, RGD:4107086 NCBI chr16:68,575,763...68,613,905
Ensembl chr16:68,575,763...68,614,286
JBrowse link
G Tcta T-cell leukemia translocation altered involved_in ISO (PMID:19560569) RGD PMID:19560569 NCBI chr 8:108,988,588...108,992,324
Ensembl chr 8:108,988,590...108,991,564
JBrowse link
G Tmem178a transmembrane protein 178A involved_in ISS
ISO
IEA
IBA
GO_REF:0000024
(MGI:5706679|PMID:26644563)
GO_REF:0000107
PMID:21873635
UniProt
RGD
Ensembl
PMID:26644563 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:5706679, RGD:13792537 NCBI chr 6:14,004,629...14,063,677
Ensembl chr 6:14,004,630...14,063,549
JBrowse link
G Tnfaip6 TNF alpha induced protein 6 involved_in ISO
IEA
(PMID:18586671)
GO_REF:0000107
RGD
Ensembl
PMID:18586671 GO_REF:0000107 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B involved_in IEA
ISO
GO_REF:0000107
(MGI:6810809|PMID:9168977)
Ensembl
RGD
PMID:9168977 GO_REF:0000107 MGI:6810809 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538
JBrowse link
G Tob2 transducer of ERBB2, 2 acts_upstream_of_or_within ISO MGI:3789484 (MGI:3785228|PMID:18358842) RGD PMID:18358842 MGI:3785228 NCBI chr 7:113,362,703...113,371,423
Ensembl chr 7:113,361,148...113,372,688
JBrowse link
G Ubash3b ubiquitin associated and SH3 domain containing, B acts_upstream_of_or_within ISO (MGI:5619442|PMID:23149425) RGD PMID:23149425 MGI:5619442 NCBI chr 8:41,385,419...41,532,248
Ensembl chr 8:41,388,341...41,532,201
JBrowse link
negative regulation of positive thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:5320871|PMID:22080863)
UniProt
RGD
PMID:22080863 GO_REF:0000024 MGI:5320871 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627
JBrowse link
negative regulation of regulatory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd44 CD44 molecule (Indian blood group) involved_in ISO (MGI:5688819|PMID:25065622) RGD PMID:25065622 MGI:5688819 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 involved_in IBA
ISO
PMID:21873635
(PMID:18641304)
RGD PMID:18641304 PMID:21873635 RGD:13792537 NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 IMP RGD PMID:30287503 RGD:38549580 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Irf1 interferon regulatory factor 1 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:3803082|PMID:18641303)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:18641303 GO_REF:0000024 GO_REF:0000107 MGI:3803082 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
JBrowse link
G Lag3 lymphocyte activating 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:3510279|PMID:15485628)
UniProt
RGD
PMID:15485628 GO_REF:0000024 MGI:3510279 NCBI chr 4:157,712,665...157,722,229
Ensembl chr 4:157,712,667...157,720,404
JBrowse link
G Mdk midkine involved_in ISO
ISS
(PMID:22323540)
GO_REF:0000024
RGD
UniProt
PMID:22323540 GO_REF:0000024 NCBI chr 3:77,901,156...77,903,997
Ensembl chr 3:77,901,158...77,903,130
JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:3806904|PMID:18713990) RGD PMID:18713990 MGI:3806904 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788
JBrowse link
G Tug1 taurine up-regulated 1 IMP RGD PMID:30287503 RGD:38549580 NCBI chr14:78,519,894...78,526,927
Ensembl chr14:78,522,506...78,526,927
JBrowse link
negative regulation of T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd74 CD74 molecule acts_upstream_of_or_within ISO MGI:1927205 (MGI:52620|PMID:7679955) RGD PMID:7679955 MGI:52620 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Cyld CYLD lysine 63 deubiquitinase acts_upstream_of_or_within ISO (MGI:5449492|PMID:23066153) RGD PMID:23066153 MGI:5449492 NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658
JBrowse link
G Dtx1 deltex E3 ubiquitin ligase 1 acts_upstream_of_or_within ISO (MGI:2663321|PMID:12794108) RGD PMID:12794108 MGI:2663321 NCBI chr12:35,849,647...35,880,835
Ensembl chr12:35,849,617...35,880,838
JBrowse link
G Ifnb1 interferon beta 1 involved_in ISO (PMID:20554961) RGD PMID:20554961 NCBI chr 5:103,020,969...103,021,523
Ensembl chr 5:103,020,969...103,021,523
JBrowse link
G Ifnl1 interferon, lambda 1 involved_in ISO (PMID:19346497) RGD PMID:19346497 NCBI chr 1:83,798,651...83,800,297 JBrowse link
G Nrarp Notch-regulated ankyrin repeat protein acts_upstream_of_or_within ISO (MGI:2663321|PMID:12794108) RGD PMID:12794108 MGI:2663321 NCBI chr 3:7,992,582...7,995,136
Ensembl chr 3:7,992,552...7,995,133
JBrowse link
G Prdx2 peroxiredoxin 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2668456 (MGI:3796974|PMID:16290204)
Ensembl
RGD
PMID:16290204 GO_REF:0000107 MGI:3796974 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194
JBrowse link
negative regulation of T cell differentiation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in ISO (PMID:12421925) RGD PMID:12421925 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Foxj1 forkhead box J1 involved_in ISO (MGI:3713603|PMID:16339515) RGD PMID:16339515 MGI:3713603 NCBI chr10:101,566,299...101,570,249 JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in ISO (MGI:3836494|PMID:19109233) RGD PMID:19109233 MGI:3836494 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532
JBrowse link
G Nfkbid NFKB inhibitor delta acts_upstream_of_or_within ISO (MGI:2177878|PMID:11931770) RGD PMID:11931770 MGI:2177878 NCBI chr 1:85,679,353...85,690,415
Ensembl chr 1:85,680,861...85,690,447
JBrowse link
G Rag2 recombination activating 2 IMP RGD PMID:30206106 RGD:38508903 NCBI chr 3:87,902,373...87,910,227
Ensembl chr 3:87,902,238...87,911,066
JBrowse link
G Zc3h8 zinc finger CCCH type containing 8 involved_in ISO (PMID:12153508) RGD PMID:12153508 NCBI chr 3:116,176,779...116,193,752
Ensembl chr 3:116,176,798...116,193,787
JBrowse link
negative regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il4r interleukin 4 receptor acts_upstream_of_or_within ISO MGI:96109 (MGI:3761239|PMID:16424184) RGD PMID:16424184 MGI:3761239 NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980
JBrowse link
G Jak3 Janus kinase 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:3719947|PMID:16020505)
BHF-UCL
RGD
PMID:16020505 GO_REF:0000024 MGI:3719947 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536
JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:4942267|PMID:9670042) RGD PMID:9670042 MGI:4942267 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788
JBrowse link
negative regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 involved_in ISO (PMID:23169781) RGD PMID:23169781 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Il2 interleukin 2 involved_in ISO RNAcentral:URS000039ED8D_10090 (MGI:5634593|PMID:25642768) RGD PMID:25642768 MGI:5634593 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il4 interleukin 4 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3817792|PMID:18792410)
RGD PMID:18792410 PMID:21873635 MGI:3817792, RGD:13792537 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 involved_in ISO (MGI:6142401|PMID:25282160) RGD PMID:25282160 MGI:6142401 NCBI chr13:73,174,075...73,245,762
Ensembl chr13:73,173,946...73,238,839
JBrowse link
G Rc3h2 ring finger and CCCH-type domains 2 involved_in ISO (MGI:6142401|PMID:25282160) RGD PMID:25282160 MGI:6142401 NCBI chr 3:21,121,531...21,186,711
Ensembl chr 3:21,110,679...21,179,933
JBrowse link
G Smad7 SMAD family member 7 involved_in IEA
ISO
GO_REF:0000107
(MGI:5634593|PMID:25642768)
Ensembl
RGD
PMID:25642768 GO_REF:0000107 MGI:5634593 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO (MGI:4868293|PMID:21151104) RGD PMID:21151104 MGI:4868293 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831
JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B acts_upstream_of_or_within ISO MGI:3530739 (MGI:5450776|PMID:23034280) RGD PMID:23034280 MGI:5450776 NCBI chr 2:174,795,831...174,811,980
Ensembl chr 2:174,797,453...174,814,236
JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in ISS
ISO
GO_REF:0000024
(MGI:6142401|PMID:25282160)
UniProt
RGD
PMID:25282160 GO_REF:0000024 MGI:6142401 NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351
JBrowse link
negative regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Loxl3 lysyl oxidase-like 3 involved_in ISO (MGI:5825383|PMID:28065600) RGD PMID:28065600 MGI:5825383 NCBI chr 4:115,540,640...115,556,958
Ensembl chr 4:115,540,685...115,557,466
JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO (MGI:4868293|PMID:21151104) RGD PMID:21151104 MGI:4868293 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831
JBrowse link
G Tnfsf18 TNF superfamily member 18 involved_in ISO (MGI:5551556|PMID:24107315) RGD PMID:24107315 MGI:5551556 NCBI chr13:73,833,478...73,907,249
Ensembl chr13:73,831,252...73,843,169
JBrowse link
negative regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:17008549)
UniProt
RGD
PMID:17008549 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within ISO MGI:96559 (MGI:2450484|PMID:12594267) RGD PMID:12594267 MGI:2450484 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
JBrowse link
G Hlx H2.0-like homeobox acts_upstream_of_or_within ISO MGI:105367|MGI:2182089 (MGI:3761239|PMID:16424184) RGD PMID:16424184 MGI:3761239 NCBI chr13:96,280,335...96,285,750
Ensembl chr13:96,280,339...96,285,750
JBrowse link
G Socs5 suppressor of cytokine signaling 5 involved_in ISO (MGI:3687909|PMID:12242343) RGD PMID:12242343 MGI:3687909 NCBI chr 6:7,481,039...7,512,644
Ensembl chr 6:7,481,095...7,514,834
JBrowse link
G Zfp35 zinc finger protein 35 acts_upstream_of_or_within ISO MGI:4398896 (MGI:4366385|PMID:19783676) RGD PMID:19783676 MGI:4366385 NCBI chr18:15,268,852...15,284,334
Ensembl chr18:15,268,814...15,285,088
JBrowse link
negative regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rc3h1 ring finger and CCCH-type domains 1 acts_upstream_of_or_within ISO MGI:3581675 (MGI:3580753|PMID:15917799) RGD PMID:15917799 MGI:3580753 NCBI chr13:73,174,075...73,245,762
Ensembl chr13:73,173,946...73,238,839
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19541
    cellular process 18407
      negative regulation of cellular process 5143
        negative regulation of cell differentiation 745
          negative regulation of leukocyte differentiation 109
            negative regulation of dendritic cell differentiation 3
            negative regulation of lymphocyte differentiation + 61
            negative regulation of myeloid leukocyte differentiation + 52
Path 2
Term Annotations click to browse term
  biological_process 19541
    developmental process 6920
      anatomical structure development 6337
        multicellular organism development 5765
          system development 5408
            immune system development 1108
              hematopoietic or lymphoid organ development 1041
                hemopoiesis 989
                  regulation of hemopoiesis 413
                    regulation of leukocyte differentiation 325
                      negative regulation of leukocyte differentiation 109
                        negative regulation of dendritic cell differentiation 3
                        negative regulation of lymphocyte differentiation + 61
                        negative regulation of myeloid leukocyte differentiation + 52
paths to the root