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ONTOLOGY REPORT - ANNOTATIONS

Term:endodermal cell differentiation
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Accession:GO:0035987 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo.
Synonyms:exact_synonym: endoderm cell differentiation


show annotations for term's descendants           Sort by:
endodermal cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRD3 bromodomain containing 3 involved_in IDA
IEA		 (PMID:32895492) UniProt
Ensembl		 PMID:32895492 GO_REF:0000107 NCBI chr 9:134,030,305...134,068,548
Ensembl chr 9:134,030,305...134,068,535 		JBrowse link
G COL11A1 collagen type XI alpha 1 chain involved_in IEP (PMID:23154389) UniProt PMID:23154389 NCBI chr 1:102,876,473...103,108,522
Ensembl chr 1:102,876,467...103,108,872 		JBrowse link
G COL12A1 collagen type XII alpha 1 chain involved_in IEP
IBA		 (PMID:23154389) UniProt
GO_Central		 PMID:23154389 GO_REF:0000033 NCBI chr 6:75,084,326...75,206,053
Ensembl chr 6:75,084,326...75,206,267 		JBrowse link
G COL4A2 collagen type IV alpha 2 chain involved_in IEP (PMID:23154389) UniProt PMID:23154389 NCBI chr13:110,307,284...110,513,209
Ensembl chr13:110,305,812...110,513,209 		JBrowse link
G COL6A1 collagen type VI alpha 1 chain involved_in IEP (PMID:23154389) UniProt PMID:23154389 NCBI chr21:45,981,770...46,005,048
Ensembl chr21:45,981,770...46,005,050 		JBrowse link
G COL7A1 collagen type VII alpha 1 chain involved_in IEP (PMID:23154389) UniProt PMID:23154389 NCBI chr 3:48,564,073...48,595,329
Ensembl chr 3:48,564,073...48,595,329 		JBrowse link
G COL8A1 collagen type VIII alpha 1 chain involved_in IEP (PMID:23154389) UniProt PMID:23154389 NCBI chr 3:99,638,594...99,799,217
Ensembl chr 3:99,638,475...99,799,226 		JBrowse link
G FN1 fibronectin 1 involved_in IDA (PMID:23154389) UniProt PMID:23154389 NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073 		JBrowse link
G GATA6 GATA binding protein 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9832509) Ensembl
MGI		 PMID:9832509 GO_REF:0000107 NCBI chr18:22,169,589...22,202,528
Ensembl chr18:22,169,589...22,202,528 		JBrowse link
G GRB2 growth factor receptor bound protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16908534) Ensembl
MGI		 PMID:16908534 GO_REF:0000107 NCBI chr17:75,318,076...75,405,678
Ensembl chr17:75,318,076...75,405,709 		JBrowse link
G GSC-DT GSC divergent transcript involved_in IDA (PMID:32895492) UniProt PMID:32895492 NCBI chr14:94,770,642...94,773,607 JBrowse link
G HMGA2 high mobility group AT-hook 2 involved_in IMP (PMID:17624332) UniProt PMID:17624332 NCBI chr12:65,824,460...65,966,291
Ensembl chr12:65,824,460...65,966,291 		JBrowse link
G HSBP1 heat shock factor binding protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24380799) Ensembl
MGI		 PMID:24380799 GO_REF:0000107 NCBI chr16:83,807,978...83,819,737
Ensembl chr16:83,719,311...83,819,737 		JBrowse link
G INHBA inhibin subunit beta A involved_in IDA (PMID:21828274) BHF-UCL PMID:21828274 NCBI chr 7:41,685,114...41,705,406
Ensembl chr 7:41,667,168...41,705,834 		JBrowse link
G ITGA4 integrin subunit alpha 4 involved_in IEP (PMID:23154389) UniProt PMID:23154389 NCBI chr 2:181,457,205...181,538,940
Ensembl chr 2:181,457,202...181,538,940 		JBrowse link
G ITGA5 integrin subunit alpha 5 involved_in IMP (PMID:23154389) UniProt PMID:23154389 NCBI chr12:54,395,261...54,419,266
Ensembl chr12:54,395,261...54,419,266 		JBrowse link
G ITGA7 integrin subunit alpha 7 involved_in IEP (PMID:23154389) UniProt PMID:23154389 NCBI chr12:55,684,568...55,716,400
Ensembl chr12:55,684,568...55,716,404 		JBrowse link
G ITGAV integrin subunit alpha V involved_in IMP (PMID:23154389) UniProt PMID:23154389 NCBI chr 2:186,590,056...186,680,901
Ensembl chr 2:186,590,010...186,680,901 		JBrowse link
G ITGB2 integrin subunit beta 2 involved_in IEP (PMID:23154389) UniProt PMID:23154389 NCBI chr21:44,885,953...44,928,815
Ensembl chr21:44,885,953...44,931,989 		JBrowse link
G ITGB5 integrin subunit beta 5 involved_in IEP (PMID:23154389) UniProt PMID:23154389 NCBI chr 3:124,761,948...124,901,418
Ensembl chr 3:124,761,948...124,901,418 		JBrowse link
G LAMA3 laminin subunit alpha 3 involved_in IEP (PMID:23154389) UniProt PMID:23154389 NCBI chr18:23,689,453...23,955,066
Ensembl chr18:23,689,453...23,956,222 		JBrowse link
G LAMB1 laminin subunit beta 1 involved_in IEP (PMID:23154389) UniProt PMID:23154389 NCBI chr 7:107,923,799...108,003,161
Ensembl chr 7:107,923,799...108,003,213 		JBrowse link
G LAMB3 laminin subunit beta 3 involved_in IEP (PMID:23154389) UniProt PMID:23154389 NCBI chr 1:209,614,870...209,652,425
Ensembl chr 1:209,614,870...209,652,425 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:16908534) Ensembl
MGI		 PMID:16908534 GO_REF:0000107 NCBI chr15:66,386,912...66,491,544
Ensembl chr15:66,386,837...66,491,656 		JBrowse link
G MIXL1 Mix paired-like homeobox involved_in ISS
IEA		 BHF-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:226,223,664...226,227,060
Ensembl chr 1:226,223,618...226,227,060 		JBrowse link
G MMP14 matrix metallopeptidase 14 involved_in IEP (PMID:23154389) UniProt PMID:23154389 NCBI chr14:22,836,585...22,847,758
Ensembl chr14:22,836,560...22,849,041 		JBrowse link
G MMP15 matrix metallopeptidase 15 involved_in IEP (PMID:23154389) UniProt PMID:23154389 NCBI chr16:58,025,754...58,046,901
Ensembl chr16:58,025,754...58,046,901 		JBrowse link
G MMP2 matrix metallopeptidase 2 involved_in IEP (PMID:23154389) UniProt PMID:23154389 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP8 matrix metallopeptidase 8 involved_in IEP (PMID:23154389) UniProt PMID:23154389 NCBI chr11:102,711,796...102,724,954
Ensembl chr11:102,711,796...102,727,050 		JBrowse link
G MMP9 matrix metallopeptidase 9 involved_in IEP (PMID:23154389) UniProt PMID:23154389 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MYH9 myosin heavy chain 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:36,281,280...36,387,967
Ensembl chr22:36,281,280...36,388,010 		JBrowse link
G NODAL nodal growth differentiation factor involved_in IMP (PMID:21741376) BHF-UCL PMID:21741376 NCBI chr10:70,431,936...70,447,951
Ensembl chr10:70,431,936...70,447,951 		JBrowse link
G NR0B1 nuclear receptor subfamily 0 group B member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16466956) Ensembl
MGI		 PMID:16466956 GO_REF:0000107 NCBI chr  X:30,304,206...30,309,390
Ensembl chr  X:30,304,206...30,309,390 		JBrowse link
G SETD2 SET domain containing 2, histone lysine methyltransferase involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:47,016,436...47,164,840
Ensembl chr 3:47,016,428...47,164,113 		JBrowse link
G SOX17 SRY-box transcription factor 17 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:17940068) Ensembl
MGI		 PMID:17940068 GO_REF:0000107 NCBI chr 8:54,457,935...54,460,892
Ensembl chr 8:54,457,935...54,460,892 		JBrowse link
G VTN vitronectin involved_in IDA (PMID:23154389) UniProt PMID:23154389 NCBI chr17:28,367,284...28,370,307
Ensembl chr17:28,367,284...28,373,091 		JBrowse link
endodermal cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDC73 cell division cycle 73 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:193,122,031...193,254,815
Ensembl chr 1:193,121,983...193,254,815 		JBrowse link
G CTNNB1 catenin beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12194849) Ensembl
MGI		 PMID:12194849 GO_REF:0000107 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096 		JBrowse link
G CTR9 CTR9 homolog, Paf1/RNA polymerase II complex component involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr11:10,751,246...10,779,746
Ensembl chr11:10,751,018...10,801,625 		JBrowse link
G LEO1 LEO1 homolog, Paf1/RNA polymerase II complex component involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr15:51,938,025...51,971,778
Ensembl chr15:51,938,025...51,971,778 		JBrowse link
G PAF1 PAF1 homolog, Paf1/RNA polymerase II complex component involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr19:39,385,629...39,391,106
Ensembl chr19:39,385,629...39,391,154 		JBrowse link
G POU5F1 POU class 5 homeobox 1 acts_upstream_of_or_within ISO (PMID:10742100) MGI PMID:10742100 NCBI chr 6:31,164,337...31,170,682
Ensembl chr 6:31,164,337...31,180,731 		JBrowse link
G RTF1 RTF1 homolog, Paf1/RNA polymerase II complex component involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr15:41,417,095...41,483,563
Ensembl chr15:41,408,408...41,483,563 		JBrowse link
endodermal cell fate determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GATA6 GATA binding protein 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20308546) Ensembl
MGI		 PMID:20308546 GO_REF:0000107 NCBI chr18:22,169,589...22,202,528
Ensembl chr18:22,169,589...22,202,528 		JBrowse link
G SOX17 SRY-box transcription factor 17 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20308546) Ensembl
MGI		 PMID:20308546 GO_REF:0000107 NCBI chr 8:54,457,935...54,460,892
Ensembl chr 8:54,457,935...54,460,892 		JBrowse link
endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EOMES eomesodermin involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:21245162) Ensembl
MGI
TreeGrafter
GO_Central		 PMID:21245162 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:27,715,953...27,722,713
Ensembl chr 3:27,715,949...27,722,711 		JBrowse link
G HNF1B HNF1 homeobox B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18635606) Ensembl
MGI		 PMID:18635606 GO_REF:0000107 NCBI chr17:37,686,431...37,745,059
Ensembl chr17:37,686,431...37,745,059 		JBrowse link
G NANOG Nanog homeobox acts_upstream_of_or_within IDA (PMID:20713518) MGI PMID:20713518 NCBI chr12:7,789,402...7,799,146
Ensembl chr12:7,787,794...7,799,146 		JBrowse link
G POU5F1 POU class 5 homeobox 1 acts_upstream_of_or_within IDA (PMID:20713518) MGI PMID:20713518 NCBI chr 6:31,164,337...31,170,682
Ensembl chr 6:31,164,337...31,180,731 		JBrowse link
G SOX17 SRY-box transcription factor 17 involved_in IEA
ISS		 Ensembl
BHF-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:54,457,935...54,460,892
Ensembl chr 8:54,457,935...54,460,892 		JBrowse link
G SOX2 SRY-box transcription factor 2 acts_upstream_of_or_within IDA (PMID:21245162) MGI PMID:21245162 NCBI chr 3:181,711,925...181,714,436
Ensembl chr 3:181,711,925...181,714,436 		JBrowse link
negative regulation of endodermal cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL5A1 collagen type V alpha 1 chain involved_in IDA (PMID:23154389) UniProt PMID:23154389 NCBI chr 9:134,641,803...134,844,843
Ensembl chr 9:134,641,803...134,844,843 		JBrowse link
G COL5A2 collagen type V alpha 2 chain involved_in IDA (PMID:23154389) UniProt PMID:23154389 NCBI chr 2:189,031,898...189,441,111
Ensembl chr 2:189,031,898...189,225,312 		JBrowse link
negative regulation of endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MESP1 mesoderm posterior bHLH transcription factor 1 involved_in IEA
ISS		 Ensembl
BHF-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr15:89,732,446...89,751,249
Ensembl chr15:89,749,875...89,751,249 		JBrowse link
positive regulation of endodermal cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MACROH2A1 macroH2A.1 histone involved_in IMP (PMID:23595991) UniProt PMID:23595991 NCBI chr 5:135,334,381...135,399,887
Ensembl chr 5:135,334,381...135,399,914 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16908534) Ensembl
MGI		 PMID:16908534 GO_REF:0000107 NCBI chr15:66,386,912...66,491,544
Ensembl chr15:66,386,837...66,491,656 		JBrowse link
G SOX17 SRY-box transcription factor 17 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17940068) Ensembl
MGI		 PMID:17940068 GO_REF:0000107 NCBI chr 8:54,457,935...54,460,892
Ensembl chr 8:54,457,935...54,460,892 		JBrowse link
regulation of endodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DKK1 dickkopf WNT signaling pathway inhibitor 1 involved_in IDA (PMID:20559569) BHF-UCL PMID:20559569 NCBI chr10:52,314,281...52,317,657
Ensembl chr10:52,314,281...52,318,042 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19612
    cellular process 18244
      cellular developmental process 5172
        cell differentiation 5171
          endodermal cell differentiation 52
            endodermal cell fate commitment + 15
            negative regulation of endodermal cell differentiation + 3
            positive regulation of endodermal cell differentiation 3
            regulation of endodermal cell differentiation + 7
Path 2
Term Annotations click to browse term
  biological_process 19612
    developmental process 7605
      anatomical structure development 7016
        multicellular organism development 5629
          embryo development 1396
            embryonic morphogenesis 724
              gastrulation 226
                formation of primary germ layer 145
                  endoderm formation 63
                    endodermal cell differentiation 52
                      endodermal cell fate commitment + 15
                      negative regulation of endodermal cell differentiation + 3
                      positive regulation of endodermal cell differentiation 3
                      regulation of endodermal cell differentiation + 7
paths to the root