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Gene: NR0B1 (nuclear receptor subfamily 0 group B member 1) Homo sapiens
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Symbol: NR0B1
Name: nuclear receptor subfamily 0 group B member 1
Description: Exhibits several functions, including AF-2 domain binding activity; nuclear receptor activity; and nucleic acid binding activity. Involved in several processes, including adrenal gland development; negative regulation of intracellular steroid hormone receptor signaling pathway; and regulation of transcription, DNA-templated. Localizes to several cellular components, including the centriolar satellite; nuclear speck; and polysomal ribosome. Implicated in 46 XY gonadal dysgenesis and X-linked adrenal hypoplasia congenita.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AHC; AHCH; AHX; DAX-1; DAX1; DSS; DSS-AHC critical region on the X chromosome protein 1; GTD; HHG; NROB1; nuclear hormone receptor; nuclear receptor DAX-1; nuclear receptor DAX1; nuclear receptor subfamily 0, group B, member 1; SRXY2; truncated nuclear receptor subfamily 0 group B member 1
Orthologs:
Mus musculus (house mouse) : Nr0b1 (nuclear receptor subfamily 0, group B, member 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nr0b1 (nuclear receptor subfamily 0, group B, member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nr0b1 (nuclear receptor subfamily 0 group B member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NR0B1 (nuclear receptor subfamily 0 group B member 1)
Canis lupus familiaris (dog) : NR0B1 (nuclear receptor subfamily 0 group B member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nr0b1 (nuclear receptor subfamily 0 group B member 1)
Sus scrofa (pig) : NR0B1 (nuclear receptor subfamily 0 group B member 1)
Chlorocebus sabaeus (African green monkey) : NR0B1 (nuclear receptor subfamily 0 group B member 1)
Heterocephalus glaber (naked mole-rat) : Nr0b1 (nuclear receptor subfamily 0 group B member 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 EnsemblX30,304,206 - 30,309,390 (-)Ensembl
GRCh38X30,304,206 - 30,309,390 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X30,322,539 - 30,327,495 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X30,232,506 - 30,237,413 (-)NCBINCBI36hg18NCBI36
Build 34X30,082,242 - 30,087,149NCBI
CeleraX34,444,104 - 34,449,076 (-)NCBI
Cytogenetic MapXp21.2NCBI
HuRefX28,059,200 - 28,064,172 (-)NCBIHuRef
CHM1_1X30,353,361 - 30,358,333 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on NR0B1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1350844
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.