Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:G protein-coupled receptor signaling pathway
go back to main search page
Accession:GO:0007186 term browser browse the term
Definition:The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane.
Synonyms:exact_synonym: G protein coupled receptor protein signaling pathway;   G protein coupled receptor protein signalling pathway;   G-protein coupled receptor protein signal transduction;   G-protein coupled receptor signalling pathway;   GPCR signaling pathway;   GPCR signalling pathway
 narrow_synonym: G-protein coupled receptor signaling pathway via GPCR dimer;   dimeric G-protein coupled receptor signaling pathway;   dimeric G-protein coupled receptor signalling pathway
 alt_id: GO:0038042


show annotations for term's descendants           Sort by:


Your selection has 2442 annotated objects. The maximum number of objects that can be shown is 2000. The list is too large to display.

  • Select a more specific term using the term browser
  • Download the entire list for this term
  • Display annotations for this term only (exclude descendants)


    • Term paths to the root
    Path 1
    Term Annotations click to browse term
      biological_process 17677
        cellular process 17216
          signal transduction 6927
            G protein-coupled receptor signaling pathway 2442
              G protein-coupled acetylcholine receptor signaling pathway + 18
              G protein-coupled chemorepellent receptor signaling pathway 0
              G protein-coupled dopamine receptor signaling pathway + 36
              G protein-coupled glutamate receptor signaling pathway + 16
              G protein-coupled opioid receptor signaling pathway + 10
              G protein-coupled opsin signaling pathway + 5
              G protein-coupled purinergic receptor signaling pathway + 13
              G protein-coupled receptor signaling pathway involved in dauer larval development 0
              G protein-coupled receptor signaling pathway involved in defense response to Gram-negative bacterium 0
              G protein-coupled receptor signaling pathway involved in heart process + 8
              G protein-coupled receptor signaling pathway involved in social behavior 0
              G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger + 29
              G protein-coupled serotonin receptor signaling pathway + 20
              Rho-activating G protein-coupled receptor signaling pathway 0
              adenylate cyclase-modulating G protein-coupled receptor signaling pathway + 268
              adrenergic receptor signaling pathway + 35
              angiotensin-activated signaling pathway + 21
              apelin receptor signaling pathway 3
              bombesin receptor signaling pathway 2
              calcitonin family receptor signaling pathway + 12
              cannabinoid signaling pathway + 7
              chemokine-mediated signaling pathway + 77
              cholecystokinin signaling pathway + 3
              complement component C5a signaling pathway 1
              endothelin receptor signaling pathway + 12
              follicle-stimulating hormone signaling pathway 8
              gastric inhibitory peptide signaling pathway 2
              ion channel modulating, G protein-coupled receptor signaling pathway + 9
              leukotriene signaling pathway 5
              luteinizing hormone signaling pathway + 3
              negative regulation of G protein-coupled receptor signaling pathway + 77
              neuropeptide signaling pathway + 100
              octopamine or tyramine signaling pathway + 0
              phospholipase C-activating G protein-coupled receptor signaling pathway + 125
              phospholipase C-inhibiting G protein-coupled receptor signaling pathway 2
              phospholipase D-activating G protein-coupled receptor signaling pathway 3
              positive regulation of G protein-coupled receptor signaling pathway + 45
              regulation of G protein-coupled receptor signaling pathway + 161
              somatostatin receptor signaling pathway + 5
              sphingosine-1-phosphate receptor signaling pathway 16
              tachykinin receptor signaling pathway + 8
              thrombin-activated receptor signaling pathway + 13
              thromboxane A2 signaling pathway 0
              thyroid-stimulating hormone signaling pathway 1
    Path 2
    Term Annotations click to browse term
      biological_process 17677
        biological regulation 12827
          regulation of biological process 12454
            signaling 7461
              signal transduction 6927
                G protein-coupled receptor signaling pathway 2442
                  G protein-coupled acetylcholine receptor signaling pathway + 18
                  G protein-coupled chemorepellent receptor signaling pathway 0
                  G protein-coupled dopamine receptor signaling pathway + 36
                  G protein-coupled glutamate receptor signaling pathway + 16
                  G protein-coupled opioid receptor signaling pathway + 10
                  G protein-coupled opsin signaling pathway + 5
                  G protein-coupled purinergic receptor signaling pathway + 13
                  G protein-coupled receptor signaling pathway involved in dauer larval development 0
                  G protein-coupled receptor signaling pathway involved in defense response to Gram-negative bacterium 0
                  G protein-coupled receptor signaling pathway involved in heart process + 8
                  G protein-coupled receptor signaling pathway involved in social behavior 0
                  G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger + 29
                  G protein-coupled serotonin receptor signaling pathway + 20
                  Rho-activating G protein-coupled receptor signaling pathway 0
                  adenylate cyclase-modulating G protein-coupled receptor signaling pathway + 268
                  adrenergic receptor signaling pathway + 35
                  angiotensin-activated signaling pathway + 21
                  apelin receptor signaling pathway 3
                  bombesin receptor signaling pathway 2
                  calcitonin family receptor signaling pathway + 12
                  cannabinoid signaling pathway + 7
                  chemokine-mediated signaling pathway + 77
                  cholecystokinin signaling pathway + 3
                  complement component C5a signaling pathway 1
                  endothelin receptor signaling pathway + 12
                  follicle-stimulating hormone signaling pathway 8
                  gastric inhibitory peptide signaling pathway 2
                  ion channel modulating, G protein-coupled receptor signaling pathway + 9
                  leukotriene signaling pathway 5
                  luteinizing hormone signaling pathway + 3
                  negative regulation of G protein-coupled receptor signaling pathway + 77
                  neuropeptide signaling pathway + 100
                  octopamine or tyramine signaling pathway + 0
                  phospholipase C-activating G protein-coupled receptor signaling pathway + 125
                  phospholipase C-inhibiting G protein-coupled receptor signaling pathway 2
                  phospholipase D-activating G protein-coupled receptor signaling pathway 3
                  positive regulation of G protein-coupled receptor signaling pathway + 45
                  regulation of G protein-coupled receptor signaling pathway + 161
                  somatostatin receptor signaling pathway + 5
                  sphingosine-1-phosphate receptor signaling pathway 16
                  tachykinin receptor signaling pathway + 8
                  thrombin-activated receptor signaling pathway + 13
                  thromboxane A2 signaling pathway 0
                  thyroid-stimulating hormone signaling pathway 1
    paths to the root