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ONTOLOGY REPORT - ANNOTATIONS

Term:G protein-coupled opioid receptor signaling pathway
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Accession:GO:0038003 term browser browse the term
Definition:A G protein-coupled receptor signaling pathway initiated by an opioid binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.
Synonyms:exact_synonym: opioid receptor signalling pathway
 broad_synonym: opioid receptor signaling pathway
 xref: Wikipedia:Opioid_receptor


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G protein-coupled opioid receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy8 adenylate cyclase 8 involved_in IDA PMID:16186630 UniProt PMID:16186630 RGD:13825193 NCBI chr 7:98,306,434...98,555,687
Ensembl chr 7:96,417,324...96,665,911 		JBrowse link
G Oprd1 opioid receptor, delta 1 involved_in ISO
IEA
IBA		 (PMID:9548483)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:9548483 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:149,590,244...149,624,999
Ensembl chr 5:144,306,188...144,340,960 		JBrowse link
G Oprk1 opioid receptor, kappa 1 involved_in ISO
IEA
IBA		 (PMID:8755601)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:8755601 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:18,657,866...18,675,671
Ensembl chr 5:13,860,021...13,877,823 		JBrowse link
G Oprl1 opioid related nociceptin receptor 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 3:189,209,495...189,225,406
Ensembl chr 3:168,834,003...168,839,920 		JBrowse link
G Oprm1 opioid receptor, mu 1 involved_in IEA
IBA
ISO		 GO_REF:0000108
GO_REF:0000033
MGI:104629 (PMID:6933569)		 GOC
GO_Central
RGD		 PMID:6933569 GO_REF:0000033 GO_REF:0000108 NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Penk proenkephalin involved_in ISO
IEA		 (PMID:6933569)
GO_REF:0000107		 RGD
Ensembl		 PMID:6933569 GO_REF:0000107 NCBI chr 5:21,981,381...21,987,074
Ensembl chr 5:17,183,806...17,189,129 		JBrowse link
G Sigmar1 sigma non-opioid intracellular receptor 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 5:61,700,021...61,702,799
Ensembl chr 5:56,904,159...56,907,017 		JBrowse link
adenylate cyclase-inhibiting opioid receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Oprk1 opioid receptor, kappa 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:22437504)		 UniProt
Ensembl
RGD		 PMID:22437504 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:18,657,866...18,675,671
Ensembl chr 5:13,860,021...13,877,823 		JBrowse link
G Oprm1 opioid receptor, mu 1 IDA RGD PMID:17157995 RGD:1625132 NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
negative regulation of opioid receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin, beta 2 IDA RGD PMID:34919270 RGD:401938593 NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itgb3 integrin subunit beta 3 IMP RGD PMID:17157995 RGD:1625132 NCBI chr10:90,009,927...90,067,787
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
positive regulation of opioid receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin, beta 2 IMP RGD PMID:19014370 RGD:401938609 NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
regulation of opioid receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:18439408)		 UniProt
Ensembl
RGD		 PMID:18439408 GO_REF:0000024 GO_REF:0000107 NCBI chr10:80,434,888...80,450,919
Ensembl chr10:79,938,066...79,954,083 		JBrowse link
G Syp synaptophysin involved_in IDA PMID:17005904 UniProt PMID:17005904 RGD:8554727 NCBI chr  X:17,521,348...17,536,449
Ensembl chr  X:14,849,444...14,864,745 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      signal transduction 7301
        G protein-coupled receptor signaling pathway 2463
          G protein-coupled opioid receptor signaling pathway 11
            adenylate cyclase-inhibiting opioid receptor signaling pathway + 3
            negative regulation of opioid receptor signaling pathway + 1
            positive regulation of opioid receptor signaling pathway + 2
            regulation of opioid receptor signaling pathway + 4
Path 2
Term Annotations click to browse term
  biological_process 20558
    biological regulation 13833
      regulation of biological process 13394
        signaling 7862
          signal transduction 7301
            G protein-coupled receptor signaling pathway 2463
              G protein-coupled opioid receptor signaling pathway 11
                adenylate cyclase-inhibiting opioid receptor signaling pathway + 3
                negative regulation of opioid receptor signaling pathway + 1
                positive regulation of opioid receptor signaling pathway + 2
                regulation of opioid receptor signaling pathway + 4
paths to the root