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ONTOLOGY REPORT - ANNOTATIONS


Term:G protein-coupled receptor signaling pathway involved in heart process
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Accession:GO:0086103 term browser browse the term
Definition:An G protein-coupled receptor signaling pathway which contributes to a circulatory system process carried out by the heart.
Synonyms:exact_synonym: G-protein coupled receptor signalling pathway involved in heart process;   GPCR signaling pathway involved in cardiac process;   GPCR signaling pathway involved in heart process


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G protein-coupled receptor signaling pathway involved in heart process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ramp3 receptor activity modifying protein 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:5514109|PMID:23674134)
UniProt
RGD
PMID:23674134 GO_REF:0000024 MGI:5514109 NCBI chr14:81,527,404...81,544,905 JBrowse link
adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chga chromogranin A involved_in IBA
IDA
PMID:21873635
PMID:22459152
GO_Central
UniProt
PMID:21873635, PMID:22459152 RGD:13792537, RGD:6906968 NCBI chr 6:121,696,051...121,707,399 JBrowse link
adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap13 A-kinase anchoring protein 13 involved_in ISS
ISO
GO_REF:0000024
(MGI:5770047|PMID:23658642)
UniProt
RGD
PMID:23658642 GO_REF:0000024 MGI:5770047 NCBI chr 1:129,313,183...129,619,647 JBrowse link
G Pln phospholamban acts_upstream_of_or_within ISO MGI:2158357 (MGI:1351738|PMID:10471356) RGD PMID:10471356 MGI:1351738 NCBI chr20:32,629,537...32,639,559 JBrowse link
adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pde4d phosphodiesterase 4D involved_in IC PMID:19801680 BHF-UCL PMID:19801680 RGD:7327160 NCBI chr 2:40,014,933...41,529,190 JBrowse link
angiotensin-activated signaling pathway involved in heart process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P09470 (MGI:5607357|PMID:25017399)
Ensembl
RGD
PMID:25017399 GO_REF:0000107 MGI:5607357 NCBI chr 4:45,640,624...45,673,708 JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO UniProtKB:P09470|UniProtKB:P49817 (MGI:5607357|PMID:25017399) RGD PMID:25017399 MGI:5607357 NCBI chr 3:146,091,969...146,139,492 JBrowse link
endothelin receptor signaling pathway involved in heart process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc42 cell division cycle 42 involved_in ISO (MGI:6362316|PMID:31219639) RGD PMID:31219639 MGI:6362316 NCBI chr 5:149,555,069...149,593,239 JBrowse link
G Edn1 endothelin 1 involved_in ISO (MGI:6362316|PMID:31219639) RGD PMID:31219639 MGI:6362316 NCBI chr17:22,454,924...22,460,812 JBrowse link
G Ednra endothelin receptor type A involved_in ISO MGI:2687362 (MGI:6362316|PMID:31219639) RGD PMID:31219639 MGI:6362316 NCBI chr19:30,233,540...30,303,727 JBrowse link
negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 involved_in ISO (PMID:17242280) RGD PMID:17242280 NCBI chr13:45,156,137...45,255,292 JBrowse link
G Gnai2 G protein subunit alpha i2 IDA RGD PMID:12631586 RGD:13508593 NCBI chr 8:108,288,401...108,309,009 JBrowse link
G Pde4b phosphodiesterase 4B involved_in IEA
ISO
GO_REF:0000107
(MGI:5286798|PMID:21670503)
Ensembl
RGD
PMID:21670503 GO_REF:0000107 MGI:5286798 NCBI chr 5:116,799,827...117,367,707 JBrowse link
negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rgs2 regulator of G-protein signaling 2 involved_in ISO (MGI:5009116|PMID:21291891) RGD PMID:21291891 MGI:5009116 NCBI chr13:55,799,749...55,802,354 JBrowse link
positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nos1 nitric oxide synthase 1 involved_in ISO (MGI:3771112|PMID:17242280) RGD PMID:17242280 MGI:3771112 NCBI chr12:38,615,111...38,795,492 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    signaling 7457
      signal transduction 6880
        G protein-coupled receptor signaling pathway 2333
          G protein-coupled receptor signaling pathway involved in heart process 15
            G protein-coupled acetylcholine receptor signaling pathway involved in heart process + 0
            adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process + 8
            adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process + 1
            angiotensin-activated signaling pathway involved in heart process + 2
            endothelin receptor signaling pathway involved in heart process 3
Path 2
Term Annotations click to browse term
  biological_process 19492
    biological regulation 13513
      regulation of biological process 12769
        regulation of cellular process 12271
          signal transduction 6880
            G protein-coupled receptor signaling pathway 2333
              G protein-coupled receptor signaling pathway involved in heart process 15
                G protein-coupled acetylcholine receptor signaling pathway involved in heart process + 0
                adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process + 8
                adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process + 1
                angiotensin-activated signaling pathway involved in heart process + 2
                endothelin receptor signaling pathway involved in heart process 3
paths to the root