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ONTOLOGY REPORT - ANNOTATIONS


Term:cannabinoid signaling pathway
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Accession:GO:0038171 term browser browse the term
Definition:The series of molecular signals generated as a consequence of a cannabinoid binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription. Cannabinoids are a class of diverse chemical compounds that include the endocannabinoids and the phytocannabinoids.
Synonyms:exact_synonym: cannabinoid receptor signaling pathway;   cannabinoid-activated signaling pathway;   cannabinoid-mediated signaling pathway


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cannabinoid signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnr1 cannabinoid receptor 1 involved_in IBA
ISO
IDA
PMID:21873635
(MGI:5819353|PMID:16540577)
(PMID:17895407)
RGD PMID:16540577 PMID:17895407, PMID:21873635, PMID:17895407 MGI:5819353, RGD:13792537, RGD:13461761 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Cnr2 cannabinoid receptor 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126
JBrowse link
G Gpr55 G protein-coupled receptor 55 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 9:92,961,431...93,011,157
Ensembl chr 9:92,962,738...92,963,697
JBrowse link
endocannabinoid signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox15b arachidonate 15-lipoxygenase, type B involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:11956198)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:11956198 GO_REF:0000024 GO_REF:0000107 NCBI chr10:55,773,748...55,783,489
Ensembl chr10:55,774,006...55,783,489
JBrowse link
G Dagla diacylglycerol lipase, alpha involved_in
acts_upstream_of_or_within
IBA
ISO
ISS
PMID:21873635
MGI:4438719 (MGI:4437165|PMID:20147530)
GO_REF:0000024
RGD
UniProt
PMID:20147530, PMID:21873635 GO_REF:0000024 MGI:4437165, RGD:13792537 NCBI chr 1:226,297,013...226,353,712
Ensembl chr 1:226,297,016...226,353,611
JBrowse link
G Daglb diacylglycerol lipase, beta involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:13,113,073...13,157,748
Ensembl chr12:13,113,237...13,157,666
JBrowse link
regulation of endocannabinoid signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd6 abhydrolase domain containing 6, acylglycerol lipase acts_upstream_of_or_within ISO (MGI:4829719|PMID:20657592) RGD PMID:20657592 MGI:4829719 NCBI chr15:18,647,903...18,695,133
Ensembl chr15:18,647,844...18,695,133
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha involved_in ISS
ISO
GO_REF:0000024
(MGI:5494205|PMID:23502535)
UniProt
RGD
PMID:23502535 GO_REF:0000024 MGI:5494205 NCBI chr18:56,193,978...56,295,869
Ensembl chr18:56,193,978...56,295,869
JBrowse link
G Mgll monoglyceride lipase involved_in ISO (MGI:4836780|PMID:20729846) RGD PMID:20729846 MGI:4836780 NCBI chr 4:120,671,436...120,773,458
Ensembl chr 4:120,671,489...120,771,088
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    signaling 7458
      signal transduction 6881
        G protein-coupled receptor signaling pathway 2331
          cannabinoid signaling pathway 9
            endocannabinoid signaling pathway + 6
Path 2
Term Annotations click to browse term
  biological_process 19491
    biological regulation 13514
      regulation of biological process 12772
        regulation of cellular process 12273
          signal transduction 6881
            G protein-coupled receptor signaling pathway 2331
              cannabinoid signaling pathway 9
                endocannabinoid signaling pathway + 6
paths to the root