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ONTOLOGY REPORT - ANNOTATIONS


Term:adrenergic receptor signaling pathway
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Accession:GO:0071875 term browser browse the term
Definition:A series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands.
Synonyms:exact_synonym: adrenergic receptor signalling pathway;   adrenoceptor signaling pathway


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adrenergic receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1b adrenoceptor alpha 1B involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr10:28,255,025...28,373,418 JBrowse link
G Adra1d adrenoceptor alpha 1D involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 3:118,793,356...118,809,354 JBrowse link
G Adra2a adrenoceptor alpha 2A involved_in ISO (PMID:10948191) RGD PMID:10948191 NCBI chr 1:253,061,480...253,064,280 JBrowse link
G Adra2b adrenoceptor alpha 2B involved_in ISO (PMID:17215105) RGD PMID:17215105 NCBI chr 3:114,585,174...114,589,220 JBrowse link
G Adra2c adrenoceptor alpha 2C involved_in ISO (PMID:17215105) RGD PMID:17215105 NCBI chr14:75,471,143...75,472,846 JBrowse link
G Adrb2 adrenoceptor beta 2 involved_in ISO
IEA
(PMID:19710023)
GO_REF:0000107
RGD
Ensembl
PMID:19710023 GO_REF:0000107 NCBI chr18:55,642,459...55,644,501 JBrowse link
G Akap13 A-kinase anchoring protein 13 involved_in IBA
ISS
ISO
IMP
PMID:21873635
GO_REF:0000024
(PMID:21224381), (PMID:23090968)
UniProt
RGD
PMID:21224381 PMID:23090968, PMID:21873635, PMID:23090968 GO_REF:0000024, RGD:13792537, RGD:11059571 NCBI chr 1:129,313,183...129,619,647 JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO
IEA
MGI:2680653 (MGI:3716263|PMID:17597584)
GO_REF:0000107
RGD
Ensembl
PMID:17597584 GO_REF:0000107 MGI:3716263 NCBI chr 1:198,291,711...198,624,683 JBrowse link
G Lmbrd2 LMBR1 domain containing 2 involved_in IBA
ISO
PMID:21873635
(PMID:28388415)
RGD PMID:28388415, PMID:21873635 RGD:13792537 NCBI chr 2:58,189,558...58,251,565 JBrowse link
G Pde4d phosphodiesterase 4D involved_in IMP PMID:19801680 BHF-UCL PMID:19801680 RGD:7327160 NCBI chr 2:40,014,933...41,529,190 JBrowse link
G Zdhhc21 zinc finger DHHC-type palmitoyltransferase 21 involved_in ISO (MGI:5921050|PMID:26715683) RGD PMID:26715683 MGI:5921050 NCBI chr 5:97,227,621...97,286,866 JBrowse link
adenylate cyclase-activating adrenergic receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy9 adenylate cyclase 9 involved_in ISO (PMID:9628827) RGD PMID:9628827 NCBI chr10:11,138,966...11,262,067 JBrowse link
G Adra1a adrenoceptor alpha 1A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:40,830,125...40,935,902 JBrowse link
G Adra1b adrenoceptor alpha 1B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:28,255,025...28,373,418 JBrowse link
G Adra1d adrenoceptor alpha 1D involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:118,793,356...118,809,354 JBrowse link
G Adra2a adrenoceptor alpha 2A involved_in ISO
IBA
(PMID:12529373)
PMID:21873635
RGD PMID:12529373, PMID:21873635 RGD:13792537 NCBI chr 1:253,061,480...253,064,280 JBrowse link
G Adra2b adrenoceptor alpha 2B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:114,585,174...114,589,220 JBrowse link
G Adra2c adrenoceptor alpha 2C involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:75,471,143...75,472,846 JBrowse link
G Adrb1 adrenoceptor beta 1 involved_in ISO
IEA
ISS
IBA
(PMID:12391161), (PMID:12529373)
GO_REF:0000107
GO_REF:0000024
PMID:21873635
RGD
Ensembl
UniProt
PMID:12391161 PMID:12529373, PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 1:255,772,217...255,773,617 JBrowse link
G Adrb2 adrenoceptor beta 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:55,642,459...55,644,501 JBrowse link
G Adrb3 adrenoceptor beta 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:64,839,820...64,844,552 JBrowse link
G Drd2 dopamine receptor D2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:49,708,903...49,772,888 JBrowse link
G Drd3 dopamine receptor D3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:56,879,689...56,931,901 JBrowse link
G Drd5 dopamine receptor D5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:72,489,347...72,490,774 JBrowse link
G Gnas GNAS complex locus involved_in ISO
ISS
(PMID:12391161)
GO_REF:0000024
RGD
UniProt
PMID:12391161 GO_REF:0000024 NCBI chr 3:163,071,003...163,136,350 JBrowse link
G Gpr101 G protein-coupled receptor 101 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:135,540,042...135,543,958 JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 involved_in ISO
ISS
(PMID:12391161)
GO_REF:0000024
RGD
UniProt
PMID:12391161 GO_REF:0000024 NCBI chr 2:164,207,513...164,322,157 JBrowse link
adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chga chromogranin A involved_in IBA
IDA
PMID:21873635
PMID:22459152
GO_Central
UniProt
PMID:21873635, PMID:22459152 RGD:13792537, RGD:6906968 NCBI chr 6:121,696,051...121,707,399 JBrowse link
adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap13 A-kinase anchoring protein 13 involved_in ISS
ISO
GO_REF:0000024
(MGI:5770047|PMID:23658642)
UniProt
RGD
PMID:23658642 GO_REF:0000024 MGI:5770047 NCBI chr 1:129,313,183...129,619,647 JBrowse link
G Pln phospholamban acts_upstream_of_or_within ISO MGI:2158357 (MGI:1351738|PMID:10471356) RGD PMID:10471356 MGI:1351738 NCBI chr20:32,629,537...32,639,559 JBrowse link
adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pde4d phosphodiesterase 4D involved_in IC PMID:19801680 BHF-UCL PMID:19801680 RGD:7327160 NCBI chr 2:40,014,933...41,529,190 JBrowse link
adenylate cyclase-inhibiting adrenergic receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2a adrenoceptor alpha 2A involved_in ISO (PMID:10948191) RGD PMID:10948191 NCBI chr 1:253,061,480...253,064,280 JBrowse link
negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrdc3 arrestin domain containing 3 acts_upstream_of_or_within ISO MGI:3877613 (MGI:5302794|PMID:21982743) RGD PMID:21982743 MGI:5302794 NCBI chr 2:11,137,443...11,149,978 JBrowse link
G Crtc3 CREB regulated transcription coactivator 3 acts_upstream_of_or_within ISO (MGI:4867567|PMID:21164481) RGD PMID:21164481 MGI:4867567 NCBI chr 1:134,552,830...134,655,929 JBrowse link
negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 involved_in ISO (PMID:17242280) RGD PMID:17242280 NCBI chr13:45,156,137...45,255,292 JBrowse link
G Gnai2 G protein subunit alpha i2 IDA RGD PMID:12631586 RGD:13508593 NCBI chr 8:108,288,401...108,309,009 JBrowse link
G Pde4b phosphodiesterase 4B involved_in IEA
ISO
GO_REF:0000107
(MGI:5286798|PMID:21670503)
Ensembl
RGD
PMID:21670503 GO_REF:0000107 MGI:5286798 NCBI chr 5:116,799,827...117,367,707 JBrowse link
negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rgs2 regulator of G-protein signaling 2 involved_in ISO (MGI:5009116|PMID:21291891) RGD PMID:21291891 MGI:5009116 NCBI chr13:55,799,749...55,802,354 JBrowse link
phospholipase C-activating adrenergic receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2a adrenoceptor alpha 2A involved_in ISO (PMID:10948191) RGD PMID:10948191 NCBI chr 1:253,061,480...253,064,280 JBrowse link
positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISO (MGI:4829580|PMID:20516643) RGD PMID:20516643 MGI:4829580 NCBI chr 1:80,815,843...80,825,732 JBrowse link
positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nos1 nitric oxide synthase 1 involved_in ISO (MGI:3771112|PMID:17242280) RGD PMID:17242280 MGI:3771112 NCBI chr12:38,615,111...38,795,492 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    signaling 7457
      signal transduction 6880
        G protein-coupled receptor signaling pathway 2333
          adrenergic receptor signaling pathway 31
            MAPK-activating adrenergic receptor signaling pathway 0
            adenylate cyclase-activating adrenergic receptor signaling pathway + 26
            adenylate cyclase-inhibiting adrenergic receptor signaling pathway + 2
            phospholipase C-activating adrenergic receptor signaling pathway 1
            positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway + 2
Path 2
Term Annotations click to browse term
  biological_process 19492
    biological regulation 13513
      regulation of biological process 12769
        regulation of cellular process 12271
          signal transduction 6880
            G protein-coupled receptor signaling pathway 2333
              adrenergic receptor signaling pathway 31
                MAPK-activating adrenergic receptor signaling pathway 0
                adenylate cyclase-activating adrenergic receptor signaling pathway + 26
                adenylate cyclase-inhibiting adrenergic receptor signaling pathway + 2
                phospholipase C-activating adrenergic receptor signaling pathway 1
                positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway + 2
paths to the root