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ONTOLOGY REPORT - ANNOTATIONS

Term:G protein-coupled glutamate receptor signaling pathway
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Accession:GO:0007216 term browser browse the term
Definition:A G protein-coupled receptor signaling pathway initiated by glutamate binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.
Synonyms:exact_synonym: metabotropic glutamate receptor signaling pathway;   metabotropic glutamate receptor signalling pathway


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G protein-coupled glutamate receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07002241.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Dagla diacylglycerol lipase, alpha involved_in ISO (MGI:4880854|PMID:20159446) RGD PMID:20159446 MGI:4880854 NCBI chr 1:206,890,635...206,947,332
Ensembl chr 1:206,890,638...206,947,232 		JBrowse link
G Gnai2 G protein subunit alpha i2 NOT IDA RGD PMID:11923410 RGD:625670 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
G Grik3 glutamate ionotropic receptor kainate type subunit 3 involved_in ISO (PMID:9144652) RGD PMID:9144652 NCBI chr 5:137,767,865...137,989,617
Ensembl chr 5:137,767,865...137,984,307 		JBrowse link
G Grm1 glutamate metabotropic receptor 1 involved_in IMP
IEA
ISS
IBA
ISO		 PMID:14614461
GO_REF:0000117
GO_REF:0000024
PMID:21873635
(PMID:24603153)		 UniProt
RGD		 PMID:24603153 PMID:14614461 PMID:21873635 GO_REF:0000024 GO_REF:0000117, RGD:1304458, RGD:13792537 NCBI chr 1:5,058,285...5,453,170
Ensembl chr 1:5,058,292...5,453,170 		JBrowse link
G Grm2 glutamate metabotropic receptor 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:107,280,099...107,293,159
Ensembl chr 8:107,280,099...107,293,146 		JBrowse link
G Grm3 glutamate metabotropic receptor 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:24,364,854...24,643,972
Ensembl chr 4:24,365,115...24,609,804 		JBrowse link
G Grm4 glutamate metabotropic receptor 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:5,484,172...5,572,821
Ensembl chr20:5,481,124...5,572,821 		JBrowse link
G Grm5 glutamate metabotropic receptor 5 involved_in ISS
IEA
IMP
IBA
ISO		 GO_REF:0000024
GO_REF:0000117
PMID:1320017
PMID:21993209
PMID:21873635
(PMID:7908515)		 UniProt
RGD		 PMID:7908515 PMID:1320017 PMID:21993209 PMID:21873635 GO_REF:0000024 GO_REF:0000117, RGD:8553991, RGD:12050103, RGD:13792537 NCBI chr 1:141,310,069...141,884,980
Ensembl chr 1:141,312,368...141,882,274 		JBrowse link
G Grm6 glutamate metabotropic receptor 6 involved_in ISS
ISO
IBA		 GO_REF:0000024
(PMID:23452348)
PMID:21873635		 UniProt
RGD		 PMID:23452348 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr10:35,167,985...35,182,717
Ensembl chr10:35,167,985...35,182,717 		JBrowse link
G Grm7 glutamate metabotropic receptor 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:143,730,862...144,613,230
Ensembl chr 4:143,731,259...144,612,344 		JBrowse link
G Grm8 glutamate metabotropic receptor 8 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:55,805,762...56,731,690
Ensembl chr 4:55,805,955...56,730,831 		JBrowse link
G Homer1 homer scaffold protein 1 involved_in IDA
IEA
IBA		 GO_REF:0000002
PMID:21873635		 InterPro
RGD		 PMID:9069287 PMID:21873635 GO_REF:0000002, RGD:633021, RGD:13792537 NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785 		JBrowse link
G Homer2 homer scaffold protein 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:135,558,977...135,659,780
Ensembl chr 1:135,567,414...135,659,772 		JBrowse link
G Homer3 homer scaffold protein 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:19,132,177...19,142,739
Ensembl chr16:19,132,162...19,142,680 		JBrowse link
G Trpm1 transient receptor potential cation channel, subfamily M, member 1 involved_in ISO
IEA
ISS		 (PMID:23452348)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:23452348 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:117,718,896...117,835,434
Ensembl chr 1:117,718,896...117,834,605 		JBrowse link
G Vom2r26 vomeronasal 2 receptor, 26 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:65,129,475...65,166,916
Ensembl chr 1:65,128,187...65,165,574 		JBrowse link
G Vom2r42 vomeronasal 2 receptor, 42 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:139,549,127...139,593,601
Ensembl chr 1:139,548,980...139,763,187 		JBrowse link
adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07002241.1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108
G Grik3 glutamate ionotropic receptor kainate type subunit 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 5:137,767,865...137,989,617
Ensembl chr 5:137,767,865...137,984,307 		JBrowse link
G Grm1 glutamate metabotropic receptor 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:5,058,285...5,453,170
Ensembl chr 1:5,058,292...5,453,170 		JBrowse link
G Grm2 glutamate metabotropic receptor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000108
(MGI:69405|PMID:7965099)		 GOC
RGD		 PMID:7965099 GO_REF:0000108 MGI:69405 NCBI chr 8:107,280,099...107,293,159
Ensembl chr 8:107,280,099...107,293,146 		JBrowse link
G Grm3 glutamate metabotropic receptor 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 4:24,364,854...24,643,972
Ensembl chr 4:24,365,115...24,609,804 		JBrowse link
G Grm4 glutamate metabotropic receptor 4 involved_in ISO
ISS		 (PMID:15102938)
GO_REF:0000024		 RGD
UniProt		 PMID:15102938 GO_REF:0000024 NCBI chr20:5,484,172...5,572,821
Ensembl chr20:5,481,124...5,572,821 		JBrowse link
G Grm5 glutamate metabotropic receptor 5 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:141,310,069...141,884,980
Ensembl chr 1:141,312,368...141,882,274 		JBrowse link
G Grm6 glutamate metabotropic receptor 6 IDA RGD PMID:8389366 RGD:69945 NCBI chr10:35,167,985...35,182,717
Ensembl chr10:35,167,985...35,182,717 		JBrowse link
G Grm7 glutamate metabotropic receptor 7 involved_in IDA
IEA
ISO		 GO_REF:0000107
(PMID:9473604)		 Ensembl
RGD		 PMID:9473604 PMID:11825890 GO_REF:0000107, RGD:728749 NCBI chr 4:143,730,862...144,613,230
Ensembl chr 4:143,731,259...144,612,344 		JBrowse link
G Grm8 glutamate metabotropic receptor 8 involved_in
acts_upstream_of_or_within		 ISO
ISS
IEA
TAS		 (PMID:9473604)
(MGI:72270|PMID:7722646)
GO_REF:0000024
GO_REF:0000107
PMID:16084932		 RGD
UniProt
Ensembl		 PMID:7722646 PMID:9473604 PMID:16084932 GO_REF:0000024 GO_REF:0000107 MGI:72270, RGD:6484727 NCBI chr 4:55,805,762...56,731,690
Ensembl chr 4:55,805,955...56,730,831 		JBrowse link
G Vom2r26 vomeronasal 2 receptor, 26 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:65,129,475...65,166,916
Ensembl chr 1:65,128,187...65,165,574 		JBrowse link
G Vom2r42 vomeronasal 2 receptor, 42 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:139,549,127...139,593,601
Ensembl chr 1:139,548,980...139,763,187 		JBrowse link
phospholipase C-activating G protein-coupled glutamate receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grm1 glutamate metabotropic receptor 1 involved_in TAS PMID:12514208 UniProt PMID:12514208 RGD:728711 NCBI chr 1:5,058,285...5,453,170
Ensembl chr 1:5,058,292...5,453,170 		JBrowse link
G Grm5 glutamate metabotropic receptor 5 involved_in TAS PMID:12514208 RGD
UniProt		 PMID:12189203 PMID:12514208 RGD:625594, RGD:728711 NCBI chr 1:141,310,069...141,884,980
Ensembl chr 1:141,312,368...141,882,274 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18734
    signaling 7370
      signal transduction 6808
        G protein-coupled receptor signaling pathway 2217
          G protein-coupled glutamate receptor signaling pathway 18
            adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway 12
            phospholipase C-activating G protein-coupled glutamate receptor signaling pathway 2
Path 2
Term Annotations click to browse term
  biological_process 18734
    biological regulation 13314
      regulation of biological process 12594
        regulation of cellular process 11909
          signal transduction 6808
            cell surface receptor signaling pathway 2777
              glutamate receptor signaling pathway 60
                G protein-coupled glutamate receptor signaling pathway 18
                  adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway 12
                  phospholipase C-activating G protein-coupled glutamate receptor signaling pathway 2
paths to the root