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ONTOLOGY REPORT - ANNOTATIONS


Term:G protein-coupled glutamate receptor signaling pathway
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Accession:GO:0007216 term browser browse the term
Definition:A series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. Ends with regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: metabotropic glutamate receptor signaling pathway;   metabotropic glutamate receptor signalling pathway


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G protein-coupled glutamate receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07002241.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07061755.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AC119691.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Dagla diacylglycerol lipase, alpha involved_in IBA
ISO
PMID:21873635
(MGI:4880854|PMID:20159446)
RGD PMID:20159446 PMID:21873635 MGI:4880854, RGD:13792537 NCBI chr 1:206,890,635...206,947,332
Ensembl chr 1:206,890,638...206,947,232
JBrowse link
G Daglb diacylglycerol lipase, beta involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:11,059,732...11,102,170
Ensembl chr12:11,059,732...11,102,154
JBrowse link
G Gnai2 G protein subunit alpha i2 NOT IDA RGD PMID:11923410 RGD:625670 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979
JBrowse link
G Grik3 glutamate ionotropic receptor kainate type subunit 3 involved_in ISO (PMID:9144652) RGD PMID:9144652 NCBI chr 5:137,767,865...137,989,617
Ensembl chr 5:137,767,865...137,984,307
JBrowse link
G Grm1 glutamate metabotropic receptor 1 involved_in IMP
ISS
IEA
IBA
ISO
PMID:14614461
GO_REF:0000024
GO_REF:0000107
PMID:21873635
(PMID:24603153)
UniProt
Ensembl
RGD
PMID:24603153 PMID:14614461 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:1304458, RGD:13792537 NCBI chr 1:5,058,285...5,453,170
Ensembl chr 1:5,058,292...5,453,170
JBrowse link
G Grm2 glutamate metabotropic receptor 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:107,280,099...107,293,159
Ensembl chr 8:107,280,099...107,293,146
JBrowse link
G Grm3 glutamate metabotropic receptor 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:24,364,854...24,643,972
Ensembl chr 4:24,365,115...24,609,804
JBrowse link
G Grm4 glutamate metabotropic receptor 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:5,484,172...5,572,821
Ensembl chr20:5,481,124...5,572,821
JBrowse link
G Grm5 glutamate metabotropic receptor 5 involved_in ISS
IMP
IBA
ISO
IEA
GO_REF:0000024
PMID:1320017
PMID:21993209
PMID:21873635
(PMID:7908515)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:7908515 PMID:1320017 PMID:21993209 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:8553991, RGD:12050103, RGD:13792537 NCBI chr 1:141,310,069...141,884,980
Ensembl chr 1:141,312,368...141,882,274
JBrowse link
G Grm6 glutamate metabotropic receptor 6 involved_in ISS
ISO
IBA
GO_REF:0000024
(PMID:23452348)
PMID:21873635
UniProt
RGD
PMID:23452348 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr10:35,167,985...35,182,717
Ensembl chr10:35,167,985...35,182,717
JBrowse link
G Grm7 glutamate metabotropic receptor 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:143,730,862...144,613,230
Ensembl chr 4:143,731,259...144,612,344
JBrowse link
G Grm8 glutamate metabotropic receptor 8 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:55,805,762...56,731,690
Ensembl chr 4:55,805,955...56,730,831
JBrowse link
G Homer1 homer scaffold protein 1 involved_in IDA
IEA
IBA
GO_REF:0000002
PMID:21873635
InterPro PMID:9069287 PMID:21873635 GO_REF:0000002, RGD:633021, RGD:13792537 NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785
JBrowse link
G Homer2 homer scaffold protein 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:135,558,977...135,659,780
Ensembl chr 1:135,567,414...135,659,772
JBrowse link
G Homer3 homer scaffold protein 3 involved_in IBA
IEA
PMID:21873635
GO_REF:0000002
InterPro PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr16:19,132,177...19,142,739
Ensembl chr16:19,132,162...19,142,680
JBrowse link
G Trpm1 transient receptor potential cation channel, subfamily M, member 1 involved_in ISO
IEA
ISS
(PMID:23452348)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:23452348 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:117,718,896...117,835,434
Ensembl chr 1:117,718,896...117,834,605
JBrowse link
G Vom2r-ps45 vomeronasal 2 receptor, pseudogene 45 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:66,463,177...66,490,650 JBrowse link
adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07002241.1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108
G AABR07061755.1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108
G AC119691.1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108
G Grik3 glutamate ionotropic receptor kainate type subunit 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 5:137,767,865...137,989,617
Ensembl chr 5:137,767,865...137,984,307
JBrowse link
G Grm1 glutamate metabotropic receptor 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:5,058,285...5,453,170
Ensembl chr 1:5,058,292...5,453,170
JBrowse link
G Grm2 glutamate metabotropic receptor 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 8:107,280,099...107,293,159
Ensembl chr 8:107,280,099...107,293,146
JBrowse link
G Grm3 glutamate metabotropic receptor 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 4:24,364,854...24,643,972
Ensembl chr 4:24,365,115...24,609,804
JBrowse link
G Grm4 glutamate metabotropic receptor 4 involved_in ISO
ISS
(PMID:15102938)
GO_REF:0000024
RGD
UniProt
PMID:15102938 GO_REF:0000024 NCBI chr20:5,484,172...5,572,821
Ensembl chr20:5,481,124...5,572,821
JBrowse link
G Grm5 glutamate metabotropic receptor 5 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:141,310,069...141,884,980
Ensembl chr 1:141,312,368...141,882,274
JBrowse link
G Grm6 glutamate metabotropic receptor 6 IDA RGD PMID:8389366 RGD:69945 NCBI chr10:35,167,985...35,182,717
Ensembl chr10:35,167,985...35,182,717
JBrowse link
G Grm7 glutamate metabotropic receptor 7 involved_in IDA
IEA
ISO
GO_REF:0000107
(PMID:9473604)
Ensembl
RGD
PMID:9473604 PMID:11825890 GO_REF:0000107, RGD:728749 NCBI chr 4:143,730,862...144,613,230
Ensembl chr 4:143,731,259...144,612,344
JBrowse link
G Grm8 glutamate metabotropic receptor 8 involved_in ISO
IEA
ISS
TAS
(PMID:9473604)
GO_REF:0000107
GO_REF:0000024
PMID:16084932
RGD
Ensembl
UniProt
PMID:9473604 PMID:16084932 GO_REF:0000024 GO_REF:0000107, RGD:6484727 NCBI chr 4:55,805,762...56,731,690
Ensembl chr 4:55,805,955...56,730,831
JBrowse link
G Vom2r-ps45 vomeronasal 2 receptor, pseudogene 45 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:66,463,177...66,490,650 JBrowse link
phospholipase C-activating G protein-coupled glutamate receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grm1 glutamate metabotropic receptor 1 involved_in TAS PMID:12514208 UniProt PMID:12514208 RGD:728711 NCBI chr 1:5,058,285...5,453,170
Ensembl chr 1:5,058,292...5,453,170
JBrowse link
G Grm5 glutamate metabotropic receptor 5 involved_in TAS PMID:12514208 RGD
UniProt
PMID:12189203 PMID:12514208 RGD:625594, RGD:728711 NCBI chr 1:141,310,069...141,884,980
Ensembl chr 1:141,312,368...141,882,274
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    signaling 7460
      signal transduction 6882
        G protein-coupled receptor signaling pathway 2333
          G protein-coupled glutamate receptor signaling pathway 20
            adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway 13
            phospholipase C-activating G protein-coupled glutamate receptor signaling pathway 2
Path 2
Term Annotations click to browse term
  biological_process 19492
    biological regulation 13513
      regulation of biological process 12769
        regulation of cellular process 12228
          signal transduction 6882
            cell surface receptor signaling pathway 2779
              glutamate receptor signaling pathway 62
                G protein-coupled glutamate receptor signaling pathway 20
                  adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway 13
                  phospholipase C-activating G protein-coupled glutamate receptor signaling pathway 2
paths to the root