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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:endothelin receptor signaling pathway
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Accession:GO:0086100 term browser browse the term
Definition:A G protein-coupled receptor signaling pathway initiated by endothelin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:related_synonym: endothelin signaling pathway


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endothelin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcar1 BCAR1 scaffold protein, Cas family member involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:19086031)		 UniProt
Ensembl
RGD		 PMID:19086031 GO_REF:0000024 GO_REF:0000107 NCBI chr19:39,679,218...39,713,952
Ensembl chr19:39,679,204...39,713,907 		JBrowse link
G Bcar3 BCAR3 adaptor protein, NSP family member involved_in ISO (PMID:19086031) RGD PMID:19086031 NCBI chr 2:210,525,260...210,638,674
Ensembl chr 2:210,525,260...210,638,798 		JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein acts_upstream_of_or_within ISO MGI:5510713 (MGI:6102264|PMID:25565927) RGD PMID:25565927 MGI:6102264 NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238 		JBrowse link
G Dear dual endothelin 1, angiotensin II receptor involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 2:170,296,930...170,300,182
Ensembl chr 2:170,296,930...170,300,182 		JBrowse link
G Edn1 endothelin 1 involved_in ISO
ISS		 (PMID:19086031)
GO_REF:0000024		 RGD
UniProt		 PMID:19086031 GO_REF:0000024 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Ednra endothelin receptor type A involved_in IEA
IBA
ISO		 GO_REF:0000108
PMID:21873635
MGI:102720 (MGI:6453700|PMID:24722437)		 GOC
RGD		 PMID:24722437 PMID:21873635 GO_REF:0000108 MGI:6453700, RGD:13792537 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Ednrb endothelin receptor type B involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:1713452), (PMID:19767294), (PMID:28236341)
PMID:21873635
(MGI:2449880|PMID:12441350)
MGI:1857161 (MGI:2136077|PMID:11413164)
MGI:105923 (MGI:6453700|PMID:24722437)		 RGD PMID:1713452 PMID:11413164 PMID:12441350 PMID:19767294 PMID:24722437 More... MGI:2136077 MGI:2449880 MGI:6453700, RGD:13792537 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
G Gna11 G protein subunit alpha 11 involved_in ISO
IEA		 MGI:95776 (MGI:3773578|PMID:18199583)
GO_REF:0000107		 RGD
Ensembl		 PMID:18199583 GO_REF:0000107 MGI:3773578 NCBI chr 7:8,163,752...8,177,636
Ensembl chr 7:8,162,750...8,179,812 		JBrowse link
G Gnaq G protein subunit alpha q involved_in ISO
IEA		 MGI:95766 (MGI:3773578|PMID:18199583)
GO_REF:0000107		 RGD
Ensembl		 PMID:18199583 GO_REF:0000107 MGI:3773578 NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in ISO
ISS		 (PMID:19086031)
GO_REF:0000024		 RGD
UniProt		 PMID:19086031 GO_REF:0000024 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
G Six1 SIX homeobox 1 involved_in ISO MGI:3612276 (MGI:5903136|PMID:28455376) RGD PMID:28455376 MGI:5903136 NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975 		JBrowse link
endothelin receptor signaling pathway involved in heart process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc42 cell division cycle 42 involved_in ISO (MGI:6362316|PMID:31219639) RGD PMID:31219639 MGI:6362316 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111 		JBrowse link
G Edn1 endothelin 1 involved_in ISO (MGI:6362316|PMID:31219639) RGD PMID:31219639 MGI:6362316 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Ednra endothelin receptor type A involved_in ISO MGI:2687362 (MGI:6362316|PMID:31219639) RGD PMID:31219639 MGI:6362316 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18737
    signaling 7370
      signal transduction 6808
        G protein-coupled receptor signaling pathway 2217
          endothelin receptor signaling pathway 12
            endothelin receptor signaling pathway involved in heart process 3
Path 2
Term Annotations click to browse term
  biological_process 18737
    biological regulation 13318
      regulation of biological process 12598
        regulation of cellular process 11911
          signal transduction 6808
            G protein-coupled receptor signaling pathway 2217
              endothelin receptor signaling pathway 12
                endothelin receptor signaling pathway involved in heart process 3
paths to the root