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ONTOLOGY REPORT - ANNOTATIONS


Term:phospholipase C-inhibiting G protein-coupled receptor signaling pathway
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Accession:GO:0030845 term browser browse the term
Definition:A G protein-coupled receptor signaling pathway which proceeds with inhibition of phospholipase C (PLC) activity and a subsequent decrease in the levels of cellular inositol trisphosphate (IP3) and diacylglycerol (DAG).
Comment:This term is intended to cover steps in a GPCR signaling pathway both upstream and downstream of phospholipase C (PLC) inhibition.
Synonyms:exact_synonym: G-protein-coupled inhibitory pathway of phospholipase C;   GPCR signaling pathway coupled to inhibition of phospholipase C activity;   GPCR signaling pathway via inhibition of PLC;   PLC-inhibiting GPCR signaling pathway
 narrow_synonym: inhibition of phospholipase C activity involved in G-protein coupled receptor signalling pathway
 related_synonym: phospholipase C inhibition


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phospholipase C-inhibiting G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plek pleckstrin involved_in ISO (PMID:7782310) RGD PMID:7782310 NCBI chr14:100,151,518...100,184,192
Ensembl chr14:100,151,210...100,217,913
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Path 1
Term Annotations click to browse term
  biological_process 19491
    signaling 7458
      signal transduction 6881
        G protein-coupled receptor signaling pathway 2331
          phospholipase C-inhibiting G protein-coupled receptor signaling pathway 1
Path 2
Term Annotations click to browse term
  biological_process 19491
    biological regulation 13515
      regulation of biological process 12773
        regulation of cellular process 12275
          signal transduction 6881
            G protein-coupled receptor signaling pathway 2331
              phospholipase C-inhibiting G protein-coupled receptor signaling pathway 1
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