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ONTOLOGY REPORT - ANNOTATIONS


Term:calcitonin family receptor signaling pathway
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Accession:GO:0097646 term browser browse the term
Definition:A series of molecular signals initiated by an extracellular member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)) combining with a calcitonin family receptor on the surface of the target cell. Calcitonin family receptors may form dimers, trimers or tetramers; adrenomedullin and amylin receptors have only been observed as dimers so far.
Synonyms:exact_synonym: calcitonin family receptor signalling pathway


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adrenomedullin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin involved_in ISO (PMID:10882736), (PMID:18434369), (PMID:20074556) RGD PMID:10882736 PMID:18434369 PMID:20074556 NCBI chr 1:164,745,484...164,747,655 JBrowse link
G Calcrl calcitonin receptor like receptor involved_in ISO UniProtKB:O60895|UniProtKB:O60896 (PMID:10882736), (PMID:20074556), (PMID:22102369), (PMID:9620797)
UniProtKB:Q7YS88|UniProtKB:Q867B9 (PMID:18434369)
RGD PMID:9620797 PMID:10882736 PMID:18434369 PMID:20074556 PMID:22102369 NCBI chr 3:69,428,348...69,525,910 JBrowse link
G Ramp2 receptor activity modifying protein 2 involved_in ISO UniProtKB:Q16602 (PMID:10882736), (PMID:20074556), (PMID:22102369), (PMID:9620797)
UniProtKB:Q8WN93 (PMID:18434369)
RGD PMID:9620797 PMID:10882736 PMID:18434369 PMID:20074556 PMID:22102369 NCBI chr10:86,187,366...86,190,692 JBrowse link
G Ramp3 receptor activity modifying protein 3 involved_in ISO UniProtKB:Q16602 (PMID:10882736)
UniProtKB:Q8WN93 (PMID:18434369)
RGD PMID:10882736 PMID:18434369 NCBI chr14:81,527,404...81,544,905 JBrowse link
amylin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin involved_in ISO ComplexPortal:CPX-3186|UniProtKB:O60894|UniProtKB:O60895|UniProtKB:P30988 (PMID:22500019) RGD PMID:22500019 NCBI chr 1:164,745,484...164,747,655 JBrowse link
G Calca calcitonin-related polypeptide alpha involved_in ISO ComplexPortal:CPX-2173|UniProtKB:O60894|UniProtKB:P30988 (PMID:22500019) RGD PMID:22500019 NCBI chr 1:168,878,212...168,883,176 JBrowse link
G Calcr calcitonin receptor involved_in ISO ComplexPortal:CPX-1134|ComplexPortal:CPX-2173|UniProtKB:O60894|UniProtKB:O60895|UniProtKB:O60896|UniProtKB:P06881|UniProtKB:P10997:PRO_0000004106|UniProtKB:P12969:PRO_0000004122|UniProtKB:P35318 (PMID:14722252), (PMID:22500019) RGD PMID:14722252 PMID:22500019 NCBI chr 4:31,661,270...31,736,392 JBrowse link
G Iapp islet amyloid polypeptide involved_in IGI
ISO
PMID:22500019
ComplexPortal:CPX-2173|ComplexPortal:CPX-3187|UniProtKB:O60894|UniProtKB:O60896|UniProtKB:P30988 (PMID:22500019)
RGD PMID:22500019, PMID:22500019, PMID:22500019, PMID:22500019, PMID:22500019 RGD:12907560, RGD:12907560, RGD:12907560, RGD:12907560 NCBI chr 4:175,237,013...175,244,373 JBrowse link
G Ramp1 receptor activity modifying protein 1 involved_in ISO UniProtKB:P06881|UniProtKB:P10997:PRO_0000004106|UniProtKB:P12969:PRO_0000004122|UniProtKB:P30988|UniProtKB:P35318 (PMID:14722252), (PMID:22500019) RGD PMID:14722252 PMID:22500019 NCBI chr 9:91,765,481...91,816,152 JBrowse link
G Ramp2 receptor activity modifying protein 2 involved_in ISO UniProtKB:P12969:PRO_0000004122|UniProtKB:P30988|UniProtKB:P35318 (PMID:22500019) RGD PMID:22500019 NCBI chr10:86,187,366...86,190,692 JBrowse link
G Ramp3 receptor activity modifying protein 3 involved_in ISO ComplexPortal:CPX-1134|UniProtKB:P10997:PRO_0000004106|UniProtKB:P30988 (PMID:22500019) RGD PMID:22500019 NCBI chr14:81,527,404...81,544,905 JBrowse link
calcitonin gene-related peptide receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calca calcitonin-related polypeptide alpha involved_in ISO (PMID:10882736) RGD PMID:10882736 NCBI chr 1:168,878,212...168,883,176 JBrowse link
G Calcrl calcitonin receptor like receptor involved_in ISO UniProtKB:O60894 (PMID:10882736), (PMID:9620797)
UniProtKB:Q867C0 (PMID:18434369)
RGD PMID:9620797 PMID:10882736 PMID:18434369 NCBI chr 3:69,428,348...69,525,910 JBrowse link
G Ramp1 receptor activity modifying protein 1 involved_in ISO UniProtKB:Q16602 (PMID:10882736), (PMID:9620797) RGD PMID:9620797 PMID:10882736 NCBI chr 9:91,765,481...91,816,152 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    signaling 7457
      signal transduction 6880
        G protein-coupled receptor signaling pathway 2333
          calcitonin family receptor signaling pathway 8
            adrenomedullin receptor signaling pathway 4
            amylin receptor signaling pathway + 7
            calcitonin gene-related peptide receptor signaling pathway 3
Path 2
Term Annotations click to browse term
  biological_process 19492
    biological regulation 13513
      regulation of biological process 12769
        regulation of cellular process 12271
          signal transduction 6880
            G protein-coupled receptor signaling pathway 2333
              calcitonin family receptor signaling pathway 8
                adrenomedullin receptor signaling pathway 4
                amylin receptor signaling pathway + 7
                calcitonin gene-related peptide receptor signaling pathway 3
paths to the root