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ONTOLOGY REPORT - ANNOTATIONS


Term:G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
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Accession:GO:0007187 term browser browse the term
Definition:A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation or inhibition of a nucleotide cyclase activity and a subsequent change in the concentration of a cyclic nucleotide.
Synonyms:exact_synonym: G protein signaling, coupled to cyclic nucleotide second messenger;   G protein signalling, coupled to cyclic nucleotide second messenger;   GPCR signaling pathway via cyclic nucleotide second messenger



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G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 involved_in ISO
ISS
(PMID:15187149), (PMID:25664854)
GO_REF:0000024
RGD
UniProt
PMID:15187149 PMID:25664854 GO_REF:0000024 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:205,567,046...205,583,001
Ensembl chr 1:205,567,220...205,582,356
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103
JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278
JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:77,893,425...77,901,166
Ensembl chr 3:77,893,425...77,901,159
JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:99,284,846...99,337,252
Ensembl chr 3:99,284,846...99,337,252
JBrowse link
G Drd1 dopamine receptor D1 involved_in ISO
IBA
(PMID:1282671)
PMID:21873635
RGD PMID:1282671 PMID:21873635 RGD:13792537 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
JBrowse link
G Drd4 dopamine receptor D4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553
JBrowse link
G Galr3 galanin receptor 3 involved_in ISO
IEA
(PMID:9832121)
GO_REF:0000107
RGD
Ensembl
PMID:9832121 GO_REF:0000107 NCBI chr 7:110,603,525...110,608,429
Ensembl chr 7:110,605,226...110,607,685
JBrowse link
G Hrh1 histamine receptor H 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:147,564,781...147,649,353
Ensembl chr 4:147,645,995...147,647,455
JBrowse link
G Hrh2 histamine receptor H 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:10,368,355...10,407,791
Ensembl chr17:10,368,298...10,407,631
JBrowse link
G Hrh3 histamine receptor H3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:167,191,551...167,196,642
Ensembl chr 3:167,191,558...167,196,642
JBrowse link
G Hrh4 histamine receptor H4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:4,166,270...4,182,426
Ensembl chr18:4,166,270...4,246,345
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:36,694,174...36,695,442
Ensembl chr 2:36,694,174...36,695,442
JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:82,513,572...82,534,892
Ensembl chr 8:82,517,360...82,534,549
JBrowse link
G Htr1d 5-hydroxytryptamine receptor 1D involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:148,655,979...148,676,534
Ensembl chr 5:148,674,495...148,675,619
JBrowse link
G Htr1f 5-hydroxytryptamine receptor 1F involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:2,642,751...2,644,150
Ensembl chr11:2,642,751...2,644,150
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:86,735,793...86,756,640
Ensembl chr 9:86,742,102...86,755,108
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C involved_in TAS
IBA
PMID:21873635 RGD
GO_Central
PMID:9153397 PMID:21873635 RGD:1358735, RGD:13792537 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287
JBrowse link
G Htr4 5-hydroxytryptamine receptor 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:55,765,981...55,949,921
Ensembl chr18:55,766,725...55,949,321
JBrowse link
G Htr5a 5-hydroxytryptamine receptor 5A involved_in IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:10861802 PMID:21873635 RGD:2316997, RGD:13792537 NCBI chr 4:7,444,968...7,454,651
Ensembl chr 4:7,444,968...7,454,651
JBrowse link
G Htr5b 5-hydroxytryptamine (serotonin) receptor 5B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:32,686,911...32,699,835
Ensembl chr13:32,687,042...32,699,835
JBrowse link
G Htr6 5-hydroxytryptamine receptor 6 involved_in IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:7680751 PMID:21873635 RGD:729174, RGD:13792537 NCBI chr 5:151,295,269...151,312,853
Ensembl chr 5:151,296,662...151,311,912
JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 involved_in TAS
IBA
PMID:21873635 RGD
GO_Central
PMID:8397408 PMID:21873635 RGD:70768, RGD:13792537 NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626
JBrowse link
G LOC120093759 olfactory receptor 63-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:12,787,439...12,788,389 JBrowse link
G Olr1091 olfactory receptor 1091 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:12,450,734...12,451,668
Ensembl chr 7:12,443,016...12,454,761
JBrowse link
G Olr1095 olfactory receptor 1095 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:12,839,664...12,840,620
Ensembl chr 7:12,839,050...12,849,389
JBrowse link
G Olr1576 olfactory receptor 1576 involved_in ISO
IBA
(PMID:28842679)
PMID:21873635
(MGI:6108824|PMID:28842679)
RGD PMID:28842679 PMID:21873635 MGI:6108824, RGD:13792537 NCBI chr13:85,430,655...85,431,584
Ensembl chr13:85,424,254...85,432,107
JBrowse link
G Olr1622 olfactory receptor 1622 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:23,806,594...23,807,532
Ensembl chr15:23,806,594...23,807,532
JBrowse link
G Olr245 olfactory receptor 245 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:161,927,803...161,928,786
Ensembl chr 1:161,921,733...161,928,935
JBrowse link
G Olr515 olfactory receptor 515 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:71,703,969...71,704,934
Ensembl chr 3:71,700,759...71,705,930
JBrowse link
G Olr517 olfactory receptor 517 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:71,767,908...71,774,271
Ensembl chr 3:71,773,279...71,774,271
JBrowse link
G Olr518 olfactory receptor 518 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:71,809,718...71,810,668
Ensembl chr 3:71,809,676...71,810,668
JBrowse link
G Pth1r parathyroid hormone 1 receptor IMP RGD PMID:8662729 RGD:7207456 NCBI chr 8:110,693,910...110,725,458
Ensembl chr 8:110,697,485...110,719,729
JBrowse link
G Vipr1 vasoactive intestinal peptide receptor 1 involved_in ISO
IEA
(PMID:8390245)
GO_REF:0000107
RGD
Ensembl
PMID:8390245 GO_REF:0000107 NCBI chr 8:121,303,739...121,339,587
Ensembl chr 8:121,310,248...121,339,585
JBrowse link
G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr2 angiotensin II receptor, type 2 involved_in ISO (MGI:4399018|PMID:17000928) RGD PMID:17000928 MGI:4399018 NCBI chr  X:112,119,673...112,124,060
Ensembl chr  X:112,120,228...112,124,057
JBrowse link
G Fzd2 frizzled class receptor 2 IDA RGD PMID:12471263 RGD:727481 NCBI chr10:87,561,866...87,563,776
Ensembl chr10:87,561,326...87,565,334
JBrowse link
G Gpr3 G protein-coupled receptor 3 involved_in ISO (PMID:22685609) RGD PMID:22685609 NCBI chr 5:145,411,500...145,414,621
Ensembl chr 5:145,411,510...145,414,590
JBrowse link
G Hrh1 histamine receptor H 1 TAS RGD PMID:12419527 RGD:727463 NCBI chr 4:147,564,781...147,649,353
Ensembl chr 4:147,645,995...147,647,455
JBrowse link
G Nos2 nitric oxide synthase 2 IDA RGD PMID:12107056 RGD:625635 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18737
    signaling 7370
      signal transduction 6808
        G protein-coupled receptor signaling pathway 2217
          G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger 40
            G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger 5
Path 2
Term Annotations click to browse term
  biological_process 18737
    biological regulation 13318
      regulation of biological process 12598
        regulation of cellular process 11911
          signal transduction 6808
            G protein-coupled receptor signaling pathway 2217
              G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger 40
                G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger 5
paths to the root