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ONTOLOGY REPORT - ANNOTATIONS


Term:G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
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Accession:GO:0007187 term browser browse the term
Definition:The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation or inhibition of a nucleotide cyclase activity and a subsequent change in the concentration of a cyclic nucleotide.
Synonyms:exact_synonym: G protein signaling, coupled to cyclic nucleotide second messenger;   G protein signalling, coupled to cyclic nucleotide second messenger;   GPCR signaling pathway via cyclic nucleotide second messenger


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G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07071765.1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 Ensembl chr 8:130,283,542...130,309,980 JBrowse link
G Anxa1 annexin A1 involved_in ISO
ISS
(PMID:15187149), (PMID:25664854)
GO_REF:0000024
RGD
UniProt
PMID:15187149 PMID:25664854 GO_REF:0000024 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:224,869,087...224,885,101
Ensembl chr 1:224,882,439...224,884,205
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:64,089,028...64,091,090
Ensembl chr 4:64,088,900...64,091,090
JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:63,990,599...64,463,222
Ensembl chr17:63,990,599...63,994,169
JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:80,833,272...80,841,165
Ensembl chr 3:80,833,272...80,841,006
JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:103,966,451...104,018,815
Ensembl chr 3:103,966,451...104,018,861
JBrowse link
G Drd1 dopamine receptor D1 involved_in ISO
IBA
IEA
(PMID:1282671)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:1282671, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drd4 dopamine receptor D4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:214,278,296...214,282,818
Ensembl chr 1:214,278,296...214,281,483
JBrowse link
G Galr3 galanin receptor 3 involved_in ISO
IEA
(PMID:9832121)
GO_REF:0000107
RGD
Ensembl
PMID:9832121 GO_REF:0000107 NCBI chr 7:120,271,451...120,276,243
Ensembl chr 7:120,273,117...120,275,581
JBrowse link
G Hrh1 histamine receptor H 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:146,374,596...146,458,148
Ensembl chr 4:146,455,332...146,457,074
JBrowse link
G Hrh2 histamine receptor H 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:10,912,959...10,931,389
Ensembl chr17:10,921,507...10,952,441
JBrowse link
G Hrh3 histamine receptor H3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:175,474,310...175,479,395
Ensembl chr 3:175,473,078...175,479,395
JBrowse link
G Hrh4 histamine receptor H4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:4,365,429...4,382,599
Ensembl chr18:4,365,429...4,382,599
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:89,113,984...89,130,830
Ensembl chr 8:89,129,453...89,130,991
JBrowse link
G Htr1d 5-hydroxytryptamine receptor 1D involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:154,780,958...154,801,505
Ensembl chr 5:154,800,226...154,801,350
JBrowse link
G Htr1f 5-hydroxytryptamine receptor 1F involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:1,982,113...1,983,513
Ensembl chr11:1,982,113...1,983,513
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:93,112,781...93,130,135
Ensembl chr 9:93,112,805...93,125,014
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C involved_in TAS
IBA
PMID:21873635 RGD
GO_Central
PMID:9153397, PMID:21873635 RGD:1358735, RGD:13792537 NCBI chr  X:118,084,520...118,318,040
Ensembl chr  X:118,084,890...118,318,039
JBrowse link
G Htr4 5-hydroxytryptamine receptor 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:57,637,013...57,820,317
Ensembl chr18:57,654,290...57,819,698
JBrowse link
G Htr5a 5-hydroxytryptamine receptor 5A involved_in IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:10861802, PMID:21873635 RGD:2316997, RGD:13792537 NCBI chr 4:199,916...209,599
Ensembl chr 4:199,916...209,599
JBrowse link
G Htr5b 5-hydroxytryptamine (serotonin) receptor 5B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:37,479,758...37,492,680
Ensembl chr13:37,479,758...37,492,680
JBrowse link
G Htr6 5-hydroxytryptamine receptor 6 involved_in IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:7680751, PMID:21873635 RGD:729174, RGD:13792537 NCBI chr 5:157,501,202...157,518,870
Ensembl chr 5:157,503,040...157,518,631
JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 involved_in TAS
IBA
PMID:21873635 RGD
GO_Central
PMID:8397408, PMID:21873635 RGD:70768, RGD:13792537 NCBI chr 1:254,547,964...254,671,811
Ensembl chr 1:254,547,620...254,671,778
JBrowse link
G LOC100909683 olfactory receptor 63-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:15,722,054...15,723,428
Ensembl chr 7:15,722,177...15,723,127
JBrowse link
G Olr1090 olfactory receptor 1090 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:15,523,926...15,524,635
Ensembl chr 7:15,523,926...15,706,893
JBrowse link
G Olr1091 olfactory receptor 1091 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:15,628,665...15,629,600
Ensembl chr 7:15,628,665...15,629,600
JBrowse link
G Olr1095 olfactory receptor 1095 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:15,621,989...15,622,945
Ensembl chr 7:15,621,989...15,622,945
JBrowse link
G Olr1576 olfactory receptor 1576 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:91,481,461...91,482,390
Ensembl chr13:91,481,461...91,482,390
JBrowse link
G Olr1622 olfactory receptor 1622 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:27,438,853...27,439,791
Ensembl chr15:27,438,853...27,439,791
JBrowse link
G Olr1631 olfactory receptor 1631 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:27,484,665...27,485,639
Ensembl chr15:27,484,665...27,485,639
JBrowse link
G Olr1632 olfactory receptor 1632 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:27,499,024...27,499,998
Ensembl chr15:27,499,024...27,499,998
Ensembl chr15:27,499,024...27,499,998
JBrowse link
G Olr1635 olfactory receptor 1635 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:27,548,762...27,549,748
Ensembl chr15:27,548,762...27,549,748
JBrowse link
G Olr1875 olfactory receptor 1875 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:172,877,048...172,878,013
Ensembl chr 1:172,877,087...172,878,013
JBrowse link
G Olr240 olfactory receptor 240 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:172,094,587...172,100,921
Ensembl chr 1:172,099,992...172,100,921
JBrowse link
G Olr241 olfactory receptor 241 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:172,129,514...172,130,446
Ensembl chr 1:172,129,514...172,130,446
JBrowse link
G Olr245 olfactory receptor 245 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:172,242,504...172,243,487
Ensembl chr 1:172,242,504...172,243,487
JBrowse link
G Olr515 olfactory receptor 515 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:73,988,945...73,989,910
Ensembl chr 3:73,988,945...73,989,910
JBrowse link
G Olr517 olfactory receptor 517 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:74,052,884...74,059,247
Ensembl chr 3:74,058,255...74,059,247
JBrowse link
G Olr518 olfactory receptor 518 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:74,370,435...74,379,077
Ensembl chr 3:74,370,435...74,371,385
JBrowse link
G Olr519 olfactory receptor 519 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:74,341,751...74,342,719
Ensembl chr 3:74,341,751...74,342,719
JBrowse link
G Pth1r parathyroid hormone 1 receptor IMP RGD PMID:8662729 RGD:7207456 NCBI chr 8:118,984,531...119,012,803
Ensembl chr 8:118,988,053...119,012,671
JBrowse link
G Vipr1 vasoactive intestinal peptide receptor 1 involved_in ISO (PMID:8390245) RGD PMID:8390245 NCBI chr 8:130,283,453...130,313,431 JBrowse link
G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr2 angiotensin II receptor, type 2 involved_in ISO (MGI:4399018|PMID:17000928) RGD PMID:17000928 MGI:4399018 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842
JBrowse link
G Fzd2 frizzled class receptor 2 IDA RGD PMID:12471263 RGD:727481 NCBI chr10:90,550,147...90,552,057
Ensembl chr10:90,550,147...90,552,057
JBrowse link
G Gpr3 G protein-coupled receptor 3 involved_in ISO (PMID:22685609) RGD PMID:22685609 NCBI chr 5:151,394,118...151,397,634
Ensembl chr 5:151,394,524...151,397,603
JBrowse link
G Hrh1 histamine receptor H 1 TAS RGD PMID:12419527 RGD:727463 NCBI chr 4:146,374,596...146,458,148
Ensembl chr 4:146,455,332...146,457,074
JBrowse link
G Nos2 nitric oxide synthase 2 IDA RGD PMID:12107056 RGD:625635 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    signaling 7458
      signal transduction 6881
        G protein-coupled receptor signaling pathway 2331
          G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger 49
            G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger 5
Path 2
Term Annotations click to browse term
  biological_process 19491
    biological regulation 13515
      regulation of biological process 12773
        regulation of cellular process 12275
          signal transduction 6881
            G protein-coupled receptor signaling pathway 2331
              G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger 49
                G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger 5
paths to the root