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ONTOLOGY REPORT - ANNOTATIONS


Term:dopamine receptor signaling pathway
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Accession:GO:0007212 term browser browse the term
Definition:The series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands.
Synonyms:exact_synonym: dopamine receptor signalling pathway



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dopamine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy6 adenylate cyclase 6 involved_in ISO
IEA
(PMID:18403039)
GO_REF:0000107
RGD
Ensembl
PMID:18403039 GO_REF:0000107 NCBI chr 7:129,742,827...129,763,922
Ensembl chr 7:129,742,838...129,763,754
JBrowse link
G Arpp19 cAMP-regulated phosphoprotein 19 IEP RGD PMID:2158525 RGD:70802 NCBI chr 8:75,779,640...75,802,474
Ensembl chr 8:75,779,523...75,802,452
JBrowse link
G Caly calcyon neuron-specific vesicular protein involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:194,862,671...194,873,861
Ensembl chr 1:194,862,672...194,873,551
JBrowse link
G Drd1 dopamine receptor D1 acts_upstream_of_or_within TAS
ISO
MGI:2159306|MGI:94924|MGI:94925 (MGI:2181304|PMID:11089973), (MGI:3626135|PMID:12097513), (MGI:3663985|PMID:16908842) RGD PMID:11089973 PMID:12097513 PMID:16908842 PMID:11818555 MGI:2181304 MGI:3626135 MGI:3663985, RGD:70242 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
JBrowse link
G Drd2 dopamine receptor D2 acts_upstream_of_or_within TAS
ISO
IDA
MGI:99578 (MGI:2181304|PMID:11089973) RGD PMID:11089973 PMID:2974511 PMID:12121979 MGI:2181304, RGD:728728, RGD:1581445 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Drd3 dopamine receptor D3 TAS RGD PMID:1975644 RGD:728430 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
JBrowse link
G Drd4 dopamine receptor D4 involved_in IDA
ISO
(PMID:1840645) RGD PMID:1840645 PMID:12711714 RGD:1358607 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553
JBrowse link
G Drd5 dopamine receptor D5 involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:1831904 PMID:21873635 RGD:728422, RGD:13792537 NCBI chr14:72,489,347...72,490,774
Ensembl chr14:72,489,347...72,490,774
JBrowse link
G Gna12 G protein subunit alpha 12 TAS RGD PMID:12623966 RGD:730287 NCBI chr12:13,805,580...13,886,255
Ensembl chr12:13,805,698...13,886,255
JBrowse link
G Gnai3 G protein subunit alpha i3 involved_in ISS
ISO
GO_REF:0000024
(PMID:19478087)
UniProt
RGD
PMID:19478087 GO_REF:0000024 NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742
JBrowse link
G Gnao1 G protein subunit alpha o1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2152685 (MGI:1932004|PMID:11248120)
RGD PMID:11248120 PMID:21873635 MGI:1932004, RGD:13792537 NCBI chr19:11,034,874...11,192,502
Ensembl chr19:11,035,956...11,192,493
JBrowse link
G Gnb5 G protein subunit beta 5 involved_in ISO
IEA
ISS
IBA
(PMID:27677260)
GO_REF:0000107
GO_REF:0000024
PMID:21873635
RGD
Ensembl
UniProt
PMID:27677260 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr 8:76,076,227...76,104,151
Ensembl chr 8:76,073,306...76,105,069
JBrowse link
G Htt huntingtin acts_upstream_of_or_within ISO MGI:2177757 (MGI:3719127|PMID:17715336) RGD PMID:17715336 MGI:3719127 NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070
JBrowse link
G Klf16 Kruppel-like factor 16 acts_upstream_of_or_within ISO (MGI:2153043|PMID:11390978) RGD PMID:11390978 MGI:2153043 NCBI chr 7:9,138,503...9,148,322
Ensembl chr 7:9,138,503...9,148,317
JBrowse link
G Ncstn nicastrin acts_upstream_of_or_within ISO MGI:3796837 (MGI:5790727|PMID:27008863) RGD PMID:27008863 MGI:5790727 NCBI chr13:84,530,442...84,546,454
Ensembl chr13:84,530,440...84,546,454
JBrowse link
G Nsg1 neuronal vesicle trafficking associated 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr14:72,648,771...72,670,521
Ensembl chr14:72,648,741...72,670,514
JBrowse link
G Nsg2 neuronal vesicle trafficking associated 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:15,601,594...15,661,441
Ensembl chr10:15,601,596...15,661,441
JBrowse link
G Rgs9 regulator of G-protein signaling 9 IMP RGD PMID:15534226 RGD:1599997 NCBI chr10:94,195,265...94,270,892
Ensembl chr10:94,197,054...94,270,892
JBrowse link
G Slc1a1 solute carrier family 1 member 1 involved_in ISO (MGI:5904876|PMID:28507136), (MGI:6113717|PMID:29229708) RGD PMID:28507136 PMID:29229708 MGI:5904876 MGI:6113717 NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402
JBrowse link
adenylate cyclase-activating dopamine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy5 adenylate cyclase 5 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:99578 (MGI:2387279|PMID:12223546)
Ensembl
RGD
PMID:12223546 GO_REF:0000107 MGI:2387279 NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974
JBrowse link
G Drd1 dopamine receptor D1 involved_in
acts_upstream_of_or_within
IMP
ISO
IDA
IEA
(MGI:6158770|PMID:23842570)
MGI:95774|MGI:95777|MGI:99673 (MGI:2178201|PMID:11923452), (MGI:2387279|PMID:12223546), (MGI:2660986|PMID:12665504), (MGI:3701153|PMID:17194762), (MGI:80600|PMID:8738226), (MGI:85829|PMID:9016340)
PMID:18424554
GO_REF:0000107
(PMID:1282671), (PMID:17760784), (PMID:18403039), (PMID:2144334), (PMID:2168520), (PMID:7838121)
PMID:8702641
RGD
Ensembl
PMID:1282671 PMID:2144334 PMID:2168520 PMID:7838121 PMID:8738226 More... GO_REF:0000107 MGI:2178201 MGI:2387279 MGI:2660986 MGI:3701153 MGI:6158770 MGI:80600 MGI:85829, RGD:1581394, RGD:8554146, RGD:8553617, RGD:7248551 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
JBrowse link
G Drd3 dopamine receptor D3 involved_in
acts_upstream_of_or_within
ISO (PMID:18424554)
(MGI:3618440|PMID:16386234)
RGD PMID:16386234 PMID:18424554 MGI:3618440 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
JBrowse link
G Drd5 dopamine receptor D5 involved_in IMP
IEA
ISO
GO_REF:0000107
(PMID:1826762), (PMID:18403039)
Ensembl
RGD
PMID:1826762 PMID:18403039 PMID:12688394 PMID:15328036 GO_REF:0000107, RGD:1581394, RGD:1600979 NCBI chr14:72,489,347...72,490,774
Ensembl chr14:72,489,347...72,490,774
JBrowse link
G Gnal G protein subunit alpha L involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:95777|MGI:99578 (MGI:3701153|PMID:17194762)
RGD PMID:17194762 PMID:21873635 MGI:3701153, RGD:13792537 NCBI chr18:60,622,311...60,762,599
Ensembl chr18:60,622,311...60,762,599
JBrowse link
G Gnas GNAS complex locus involved_in
acts_upstream_of_or_within
IBA
ISO
IDA
PMID:21873635
MGI:95774|MGI:99578 (MGI:3701153|PMID:17194762)
PMID:18403039
RGD PMID:17194762 PMID:21873635 PMID:18403039 MGI:3701153, RGD:13792537, RGD:8553387 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262
JBrowse link
G Oprd1 opioid receptor, delta 1 NOT|acts_upstream_of_or_within ISO (MGI:80600|PMID:8738226) RGD PMID:8738226 MGI:80600 NCBI chr 5:144,306,188...144,340,960
Ensembl chr 5:144,306,188...144,340,960
JBrowse link
G Oprm1 opioid receptor, mu 1 acts_upstream_of_or_within ISO (MGI:80600|PMID:8738226) RGD PMID:8738226 MGI:80600 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
JBrowse link
G Ptger1 prostaglandin E receptor 1 involved_in ISO (MGI:6158770|PMID:23842570) RGD PMID:23842570 MGI:6158770 NCBI chr19:24,470,258...24,473,687
Ensembl chr19:24,467,532...24,473,559
JBrowse link
G Slc9a3r1 SLC9A3 regulator 1 acts_upstream_of_or_within ISO MGI:2386785 (MGI:4819345|PMID:20200151) RGD PMID:20200151 MGI:4819345 NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598
JBrowse link
adenylate cyclase-inhibiting dopamine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy5 adenylate cyclase 5 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:94924 (MGI:2387279|PMID:12223546)
Ensembl
RGD
PMID:12223546 GO_REF:0000107 MGI:2387279 NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974
JBrowse link
G Drd2 dopamine receptor D2 involved_in
acts_upstream_of_or_within
ISO
IDA
IBA
(PMID:1331329), (PMID:2531656)
MGI:99578|MGI:99673 (MGI:2387279|PMID:12223546), (MGI:2660986|PMID:12665504)
MGI:95772 (MGI:893272|PMID:7706278)
PMID:2410769
PMID:21873635
(PMID:26554819), (PMID:8666994)
RGD PMID:1331329 PMID:2531656 PMID:7706278 PMID:8666994 PMID:12223546 More... MGI:2387279 MGI:2660986 MGI:893272, RGD:8553953, RGD:13792537 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Drd3 dopamine receptor D3 involved_in IDA
IBA
ISO
PMID:8302280
PMID:21873635
(PMID:18424554), (PMID:7907363), (PMID:8666994)
RGD PMID:7907363 PMID:8666994 PMID:18424554 PMID:8302280 PMID:21873635 RGD:8554810, RGD:13792537 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
JBrowse link
G Drd4 dopamine receptor D4 involved_in
acts_upstream_of_or_within
ISO
IEA
ISS
(PMID:27659709), (PMID:7512953), (PMID:9003072), (PMID:9843378)
MGI:3576789 (MGI:3575384|PMID:14684868)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:7512953 PMID:9003072 PMID:9843378 PMID:14684868 PMID:27659709 GO_REF:0000024 GO_REF:0000107 MGI:3575384 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553
JBrowse link
G Flna filamin A involved_in ISO (PMID:10692483) RGD PMID:10692483 NCBI chr  X:152,007,758...152,034,266
Ensembl chr  X:152,007,758...152,031,052
JBrowse link
negative regulation of dopamine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 acts_upstream_of_or_within ISO MGI:94925|MGI:99578 (MGI:3626135|PMID:12097513)
MGI:2675755 (MGI:2181304|PMID:11089973)
RGD PMID:11089973 PMID:12097513 MGI:2181304 MGI:3626135 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Drd3 dopamine receptor D3 acts_upstream_of_or_within ISO MGI:94924|MGI:99578 (MGI:3626135|PMID:12097513) RGD PMID:12097513 MGI:3626135 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
JBrowse link
G Palm paralemmin involved_in ISO (PMID:16386234) RGD PMID:16386234 NCBI chr 7:9,886,634...9,912,389
Ensembl chr 7:9,886,643...9,912,555
JBrowse link
G Rgs4 regulator of G-protein signaling 4 IDA RGD PMID:21896332 RGD:13524519 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068
JBrowse link
phospholipase C-activating dopamine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd1 dopamine receptor D1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
UniProtKB:P14416 (PMID:17194762)
(PMID:1282671)
MGI:94924|MGI:95766|MGI:95776 (MGI:3621386|PMID:15016423), (MGI:3701153|PMID:17194762)
Ensembl
RGD
PMID:1282671 PMID:15016423 PMID:17194762 GO_REF:0000107 MGI:3621386 MGI:3701153 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
JBrowse link
G Drd2 dopamine receptor D2 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
UniProtKB:P21728 (PMID:17194762)
MGI:95766|MGI:95776|MGI:99578 (MGI:3621386|PMID:15016423), (MGI:3701153|PMID:17194762)
RGD PMID:15016423 PMID:17194762 PMID:21873635 MGI:3621386 MGI:3701153, RGD:13792537 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Drd3 dopamine receptor D3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
JBrowse link
G Gna11 G protein subunit alpha 11 involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
PMID:21873635
MGI:94924|MGI:95776|MGI:99578 (MGI:3701153|PMID:17194762)
GO_REF:0000107
RGD
Ensembl
PMID:17194762 PMID:21873635 GO_REF:0000107 MGI:3701153, RGD:13792537 NCBI chr 7:8,163,752...8,177,636
Ensembl chr 7:8,162,750...8,179,812
JBrowse link
G Gna14 G protein subunit alpha 14 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:213,714,993...213,900,083
Ensembl chr 1:213,716,020...213,897,423
JBrowse link
G Gna15 G protein subunit alpha 15 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:8,184,632...8,205,508
Ensembl chr 7:8,184,861...8,205,508
JBrowse link
G Gnaq G protein subunit alpha q involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:94924|MGI:95766|MGI:99578 (MGI:3701153|PMID:17194762)
Ensembl
RGD
PMID:17194762 GO_REF:0000107 MGI:3701153 NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672
JBrowse link
G Slc9a3r1 SLC9A3 regulator 1 acts_upstream_of_or_within ISO MGI:2386785 (MGI:4819345|PMID:20200151) RGD PMID:20200151 MGI:4819345 NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598
JBrowse link
positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prmt5 protein arginine methyltransferase 5 involved_in ISO UniProtKB:P14416 (PMID:26554819) RGD PMID:26554819 NCBI chr15:27,968,893...27,978,291
Ensembl chr15:27,968,910...27,978,296
JBrowse link
positive regulation of dopamine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav2 caveolin 2 involved_in IEA
ISS
ISO
GO_REF:0000107
PMID:15569306
(PMID:15569306)
Ensembl
RGD
PMID:15569306 PMID:15569306 GO_REF:0000107, RGD:8554731 NCBI chr 4:45,616,766...45,624,144
Ensembl chr 4:45,616,712...45,624,244
JBrowse link
G Drd3 dopamine receptor D3 acts_upstream_of_or_within ISO MGI:1857159 (MGI:3621386|PMID:15016423) RGD PMID:15016423 MGI:3621386 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:20659558) RGD PMID:20659558 NCBI chr 7:122,826,712...122,987,711
Ensembl chr 7:122,826,696...122,987,703
JBrowse link
G Vps35 VPS35 retromer complex component involved_in ISO (PMID:27460146) RGD PMID:27460146 NCBI chr19:21,765,771...21,801,620
Ensembl chr19:21,765,749...21,801,618
JBrowse link
regulation of dopamine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alk ALK receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:5700373 (MGI:5697626|PMID:17487225) RGD PMID:17487225 MGI:5697626 NCBI chr 6:22,879,653...23,599,636
Ensembl chr 6:22,880,625...23,598,034
JBrowse link
G Dtnbp1 dystrobrevin binding protein 1 involved_in IDA PMID:17989303 UniProt PMID:17989303 RGD:8553895 NCBI chr17:19,685,218...19,776,668
Ensembl chr17:19,685,215...19,776,661
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in IBA
ISO
ISS
PMID:21873635
(MGI:5553024|PMID:24464040)
GO_REF:0000024
RGD
ParkinsonsUK-UCL
PMID:24464040 PMID:21873635 GO_REF:0000024 MGI:5553024, RGD:13792537 NCBI chr 7:122,826,712...122,987,711
Ensembl chr 7:122,826,696...122,987,703
JBrowse link
G Rgs8 regulator of G-protein signaling 8 involved_in IDA PMID:9394004 UniProt PMID:9394004 RGD:69963 NCBI chr13:65,804,703...65,848,953
Ensembl chr13:65,804,797...65,846,807
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    cellular process 18359
      signal transduction 6908
        dopamine receptor signaling pathway 40
          adenylate cyclase-activating dopamine receptor signaling pathway 10
          adenylate cyclase-inhibiting dopamine receptor signaling pathway + 6
          negative regulation of dopamine receptor signaling pathway + 4
          phospholipase C-activating dopamine receptor signaling pathway + 8
          positive regulation of dopamine receptor signaling pathway + 5
          regulation of dopamine receptor signaling pathway + 11
Path 2
Term Annotations click to browse term
  biological_process 19497
    response to stimulus 10416
      cellular response to stimulus 8783
        cellular response to chemical stimulus 3562
          cellular response to organic substance 2881
            cellular response to organonitrogen compound 867
              cellular response to monoamine stimulus 113
                cellular response to catecholamine stimulus 113
                  cellular response to dopamine 93
                    dopamine receptor signaling pathway 40
                      adenylate cyclase-activating dopamine receptor signaling pathway 10
                      adenylate cyclase-inhibiting dopamine receptor signaling pathway + 6
                      negative regulation of dopamine receptor signaling pathway + 4
                      phospholipase C-activating dopamine receptor signaling pathway + 8
                      positive regulation of dopamine receptor signaling pathway + 5
                      regulation of dopamine receptor signaling pathway + 11
paths to the root