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ONTOLOGY REPORT - ANNOTATIONS

Term:angiotensin-activated signaling pathway
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Accession:GO:0038166 term browser browse the term
Definition:A G protein-coupled receptor signaling pathway initiated by angiotensin II binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: angiotensin II-mediated signaling pathway;   angiotensin receptor signaling pathway
 related_synonym: angiotensin-mediated signaling pathway


show annotations for term's descendants           Sort by:
angiotensin-activated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme involved_in IEA
ISO		 GO_REF:0000107
(PMID:25017399)		 Ensembl
RGD		 PMID:25017399 GO_REF:0000107 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Agt angiotensinogen involved_in ISO
IEA
ISS		 (PMID:24296617)
GO_REF:0000107
GO_REF:0000024
(PMID:10425188)
(PMID:15153556), (PMID:15652490), (PMID:1567413), (PMID:18971559)		 RGD
Ensembl
BHF-UCL		 PMID:1567413 PMID:10425188 PMID:15153556 PMID:15652490 PMID:18971559 More... GO_REF:0000024 GO_REF:0000107 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a involved_in IMP
ISO		 PMID:21769867
(PMID:1567413), (PMID:18971559)		 RGD PMID:1567413 PMID:18971559 PMID:21769867 RGD:5688337 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Agtr1b angiotensin II receptor, type 1b involved_in IMP PMID:21769867 RGD
BHF-UCL		 PMID:7862653 PMID:21769867 RGD:10047113, RGD:5688337 NCBI chr 2:102,844,969...102,920,232
Ensembl chr 2:102,844,969...102,920,232 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 involved_in ISO MGI:1857123 (PMID:10425188) RGD PMID:10425188 NCBI chr  X:112,119,876...112,124,060
Ensembl chr  X:112,120,228...112,124,057 		JBrowse link
G Agtrap angiotensin II receptor-associated protein involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:158,507,427...158,519,036
Ensembl chr 5:158,508,749...158,519,036 		JBrowse link
G Ahcyl1 adenosylhomocysteinase-like 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:20584908)		 UniProt
Ensembl
RGD		 PMID:20584908 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:195,294,149...195,328,586
Ensembl chr 2:195,294,153...195,345,815 		JBrowse link
G Ang2 angiogenin, ribonuclease A family, member 2 involved_in ISO (PMID:25313067) RGD PMID:25313067 NCBI chr15:24,398,330...24,415,909
Ensembl chr15:24,398,419...24,398,922 		JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha involved_in ISO
IEA		 (PMID:20584908)
GO_REF:0000107		 RGD
Ensembl		 PMID:20584908 GO_REF:0000107 NCBI chr18:56,648,779...56,711,505
Ensembl chr18:54,378,784...54,438,994 		JBrowse link
G Car2 carbonic anhydrase 2 involved_in ISO
ISS		 (PMID:15990874)
GO_REF:0000024		 RGD
UniProt		 PMID:15990874 GO_REF:0000024 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818 		JBrowse link
G Cav1 caveolin 1 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:P09470 (PMID:25017399)		 Ensembl
RGD		 PMID:25017399 GO_REF:0000107 NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Dear dual endothelin 1, angiotensin II receptor involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 2:170,296,930...170,300,182
Ensembl chr 2:170,296,930...170,300,182 		JBrowse link
G Fam114a1 family with sequence similarity 114, member A1 acts_upstream_of_or_within ISO (PMID:35671117) RGD PMID:35671117 NCBI chr14:43,275,693...43,346,154
Ensembl chr14:43,275,701...43,346,174 		JBrowse link
G Mas1l MAS1 proto-oncogene like, G protein-coupled receptor involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:47,871,592...47,879,942 JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 involved_in ISO (PMID:24206662) RGD PMID:24206662 NCBI chr19:30,715,634...31,059,885
Ensembl chr19:30,715,648...31,059,885 		JBrowse link
G Pla2g2a phospholipase A2 group IIA involved_in IEA
ISO		 GO_REF:0000107
(PMID:17069818)		 Ensembl
RGD		 PMID:17069818 GO_REF:0000107 NCBI chr 5:156,359,725...156,362,302
Ensembl chr 5:151,076,442...151,079,014 		JBrowse link
G Slc26a6 solute carrier family 26 member 6 involved_in ISO (PMID:15990874) RGD PMID:15990874 NCBI chr 8:109,558,968...109,569,778
Ensembl chr 8:109,559,642...109,569,778 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO UniProtKB:P09470|UniProtKB:P49817 (PMID:25017399) RGD PMID:25017399 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
angiotensin-activated signaling pathway involved in heart process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rac1 Rac family small GTPase 1 acts_upstream_of_or_within ISO (PMID:26975711) RGD PMID:26975711 NCBI chr12:16,150,411...16,170,864
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
G Rap1gds1 Rap1 GTPase-GDP dissociation stimulator 1 acts_upstream_of_or_within ISO
IEA		 MGI:3613572 (PMID:26975711), (PMID:29921611)
GO_REF:0000107		 RGD
Ensembl		 PMID:26975711 PMID:29921611 GO_REF:0000107 NCBI chr 2:227,500,366...227,645,213
Ensembl chr 2:227,500,367...227,645,169 		JBrowse link
negative regulation of angiotensin-activated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp3ca protein phosphatase 3 catalytic subunit alpha involved_in ISO (PMID:30718414) RGD PMID:30718414 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974 		JBrowse link
phospholipase C-activating angiotensin-activated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn2 actinin alpha 2 involved_in ISO
IEA		 (PMID:25433700)
GO_REF:0000107		 RGD
Ensembl		 PMID:25433700 GO_REF:0000107 NCBI chr17:58,143,334...58,210,622
Ensembl chr17:58,142,625...58,210,622 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a involved_in ISO (PMID:1378723) RGD PMID:1378723 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Agtr1b angiotensin II receptor, type 1b involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 2:102,844,969...102,920,232
Ensembl chr 2:102,844,969...102,920,232 		JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor involved_in ISO (PMID:16611642) RGD PMID:16611642 NCBI chr 1:47,879,956...47,911,500
Ensembl chr 1:47,880,309...47,911,709 		JBrowse link
positive regulation of angiotensin-activated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkca protein kinase C, alpha involved_in ISO
IEA		 (PMID:25313067)
GO_REF:0000107		 RGD
Ensembl		 PMID:25313067 GO_REF:0000107 NCBI chr10:93,388,991...93,787,617
Ensembl chr10:92,894,012...93,288,012 		JBrowse link
regulation of angiotensin-activated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in ISO
IEA		 (PMID:28679962)
GO_REF:0000107		 RGD
Ensembl		 PMID:28679962 GO_REF:0000107 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in ISO (PMID:28679962) RGD PMID:28679962 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      signal transduction 7301
        G protein-coupled receptor signaling pathway 2463
          angiotensin-activated signaling pathway 26
            angiotensin-activated signaling pathway involved in heart process + 2
            negative regulation of angiotensin-activated signaling pathway 1
            phospholipase C-activating angiotensin-activated signaling pathway + 4
            positive regulation of angiotensin-activated signaling pathway 1
            regulation of angiotensin-activated signaling pathway + 4
Path 2
Term Annotations click to browse term
  biological_process 20558
    response to stimulus 11067
      response to endogenous stimulus 2056
        response to hormone 1372
          response to peptide hormone 694
            cellular response to peptide hormone stimulus 460
              cellular response to angiotensin 63
                angiotensin-activated signaling pathway 26
                  angiotensin-activated signaling pathway involved in heart process + 2
                  negative regulation of angiotensin-activated signaling pathway 1
                  phospholipase C-activating angiotensin-activated signaling pathway + 4
                  positive regulation of angiotensin-activated signaling pathway 1
                  regulation of angiotensin-activated signaling pathway + 4
paths to the root