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ONTOLOGY REPORT - ANNOTATIONS


Term:angiotensin-activated signaling pathway
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Accession:GO:0038166 term browser browse the term
Definition:A G protein-coupled receptor signaling pathway initiated by angiotensin II binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: angiotensin II-mediated signaling pathway;   angiotensin receptor signaling pathway
 related_synonym: angiotensin-mediated signaling pathway



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angiotensin-activated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen involved_in ISO
ISS
(PMID:24296617)
GO_REF:0000024
RGD
BHF-UCL
PMID:24296617 GO_REF:0000024 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Agtr1a angiotensin II receptor, type 1a involved_in ISO
IMP
(PMID:1567413)
PMID:21769867
RGD PMID:1567413 PMID:21769867 RGD:5688337 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Agtr1b angiotensin II receptor, type 1b involved_in IMP PMID:21769867 RGD
BHF-UCL
PMID:7862653 PMID:21769867 RGD:10047113, RGD:5688337 NCBI chr 2:102,844,969...102,920,232
Ensembl chr 2:102,844,969...102,920,232
JBrowse link
G Agtr2 angiotensin II receptor, type 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000108
UniProtKB:P11859 (MGI:1327501|PMID:9878677)
GOC
RGD
PMID:9878677 GO_REF:0000108 MGI:1327501 NCBI chr  X:112,119,673...112,124,060
Ensembl chr  X:112,120,228...112,124,057
JBrowse link
G Agtrap angiotensin II receptor-associated protein involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000002
(MGI:1342129|PMID:10425188)
InterPro
RGD
PMID:10425188 GO_REF:0000002 MGI:1342129 NCBI chr 5:158,507,427...158,519,036
Ensembl chr 5:158,508,749...158,519,036
JBrowse link
G Ahcyl1 adenosylhomocysteinase-like 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:20584908)
UniProt
RGD
PMID:20584908 GO_REF:0000024 NCBI chr 2:195,294,149...195,328,586
Ensembl chr 2:195,294,153...195,345,815
JBrowse link
G Ang2 angiogenin, ribonuclease A family, member 2 involved_in ISO (MGI:5609214|PMID:25313067) RGD PMID:25313067 MGI:5609214 NCBI chr15:24,398,383...24,415,837
Ensembl chr15:24,398,419...24,398,922
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha involved_in ISO
IEA
(PMID:20584908)
GO_REF:0000107
RGD
Ensembl
PMID:20584908 GO_REF:0000107 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994
JBrowse link
G Car2 carbonic anhydrase 2 involved_in ISO
ISS
(PMID:15990874)
GO_REF:0000024
RGD
UniProt
PMID:15990874 GO_REF:0000024 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
JBrowse link
G Dear dual endothelin 1, angiotensin II receptor involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 2:170,296,930...170,300,182
Ensembl chr 2:170,296,930...170,300,182
JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000108
MGI:2158808 (MGI:2682326|PMID:12829792)
GOC
RGD
PMID:12829792 GO_REF:0000108 MGI:2682326 NCBI chr 1:47,879,956...47,911,500
Ensembl chr 1:47,880,309...47,911,709
JBrowse link
G Mas1l MAS1 proto-oncogene like, G protein-coupled receptor involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:47,871,592...47,879,942 JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 involved_in ISO (MGI:5548037|PMID:24206662) RGD PMID:24206662 MGI:5548037 NCBI chr19:30,715,648...31,059,885
Ensembl chr19:30,715,648...31,059,885
JBrowse link
G Slc26a6 solute carrier family 26 member 6 involved_in ISO (PMID:15990874) RGD PMID:15990874 NCBI chr 8:109,558,968...109,569,778
Ensembl chr 8:109,559,642...109,569,778
JBrowse link
angiotensin-activated signaling pathway involved in heart process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 involved_in ISO UniProtKB:P09470 (MGI:5607357|PMID:25017399) RGD PMID:25017399 MGI:5607357 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Rac1 Rac family small GTPase 1 acts_upstream_of_or_within ISO (MGI:6480257|PMID:26975711) RGD PMID:26975711 MGI:6480257 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Rap1gds1 Rap1 GTPase-GDP dissociation stimulator 1 acts_upstream_of_or_within ISO MGI:3613572 (MGI:6363885|PMID:29921611), (MGI:6480257|PMID:26975711) RGD PMID:26975711 PMID:29921611 MGI:6363885 MGI:6480257 NCBI chr 2:227,500,366...227,645,243
Ensembl chr 2:227,500,367...227,645,169
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO UniProtKB:P09470|UniProtKB:P49817 (MGI:5607357|PMID:25017399) RGD PMID:25017399 MGI:5607357 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
phospholipase C-activating angiotensin-activated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn2 actinin alpha 2 involved_in ISO (PMID:25433700) RGD PMID:25433700 NCBI chr17:58,143,334...58,210,622
Ensembl chr17:58,142,625...58,210,622
JBrowse link
G Agtr1a angiotensin II receptor, type 1a involved_in ISO (PMID:1378723) RGD PMID:1378723 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Agtr1b angiotensin II receptor, type 1b involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 2:102,844,969...102,920,232
Ensembl chr 2:102,844,969...102,920,232
JBrowse link
regulation of angiotensin-activated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in ISO
IEA
(PMID:28679962)
GO_REF:0000107
RGD
Ensembl
PMID:28679962 GO_REF:0000107 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in ISO (MGI:6158813|PMID:28679962) RGD PMID:28679962 MGI:6158813 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18734
    signaling 7370
      signal transduction 6808
        G protein-coupled receptor signaling pathway 2217
          angiotensin-activated signaling pathway 21
            angiotensin-activated signaling pathway involved in heart process + 4
            negative regulation of angiotensin-activated signaling pathway 0
            phospholipase C-activating angiotensin-activated signaling pathway + 3
            positive regulation of angiotensin-activated signaling pathway 0
            regulation of angiotensin-activated signaling pathway + 2
Path 2
Term Annotations click to browse term
  biological_process 18734
    response to stimulus 10209
      response to chemical 6156
        response to nitrogen compound 1600
          response to organonitrogen compound 1505
            cellular response to organonitrogen compound 877
              cellular response to peptide 492
                cellular response to peptide hormone stimulus 410
                  cellular response to angiotensin 45
                    angiotensin-activated signaling pathway 21
                      angiotensin-activated signaling pathway involved in heart process + 4
                      negative regulation of angiotensin-activated signaling pathway 0
                      phospholipase C-activating angiotensin-activated signaling pathway + 3
                      positive regulation of angiotensin-activated signaling pathway 0
                      regulation of angiotensin-activated signaling pathway + 2
paths to the root