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ONTOLOGY REPORT - ANNOTATIONS


Term:somatostatin receptor signaling pathway
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Accession:GO:0038169 term browser browse the term
Definition:A G protein-coupled receptor signaling pathway initiated by somatostatin binding to the somatostatin receptor (SSTR) on the surface of a target cell, and ending with the regulation of a downstream cellular process.
Comment:In addition to somatostatin (SST), the somatostatin receptors (SSTRs) can also be activated by the agonist cortistatin (CST). For signal transduction specifically initiated by the ligand somatostatin, consider instead annotating to the child term 'somatostatin signaling pathway ; GO:0038170'.
Synonyms:exact_synonym: SST receptor signaling pathway
 related_synonym: SSTR signaling pathway



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somatostatin signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sstr1 somatostatin receptor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000108
(MGI:68738|PMID:7929134)
GOC
RGD
PMID:7929134 GO_REF:0000108 MGI:68738 NCBI chr 6:75,832,292...75,836,806
Ensembl chr 6:75,832,530...75,836,802
JBrowse link
G Sstr2 somatostatin receptor 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000108
(MGI:50870|PMID:1346068)
(MGI:68738|PMID:7929134)
GOC
RGD
PMID:1346068 PMID:7929134 GO_REF:0000108 MGI:50870 MGI:68738 NCBI chr10:98,664,204...98,671,370
Ensembl chr10:98,664,216...98,674,351
JBrowse link
G Sstr3 somatostatin receptor 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 7:110,092,563...110,109,043
Ensembl chr 7:110,092,575...110,099,769
JBrowse link
G Sstr4 somatostatin receptor 4 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 3:135,854,826...135,856,689
Ensembl chr 3:135,854,826...135,856,689
JBrowse link
G Sstr5 somatostatin receptor 5 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr10:14,506,868...14,512,946
Ensembl chr10:14,506,868...14,512,946
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18737
    signaling 7370
      signal transduction 6808
        G protein-coupled receptor signaling pathway 2217
          somatostatin receptor signaling pathway 5
            somatostatin signaling pathway 5
Path 2
Term Annotations click to browse term
  biological_process 18737
    biological regulation 13318
      regulation of biological process 12598
        regulation of cellular process 11911
          signal transduction 6808
            G protein-coupled receptor signaling pathway 2217
              somatostatin receptor signaling pathway 5
                somatostatin signaling pathway 5
paths to the root