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ONTOLOGY REPORT - ANNOTATIONS


Term:thrombin-activated receptor signaling pathway
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Accession:GO:0070493 term browser browse the term
Definition:The series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands.
Synonyms:exact_synonym: thrombin receptor signaling pathway;   thrombin receptor signalling pathway


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thrombin-activated receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgkq diacylglycerol kinase, theta involved_in ISO (PMID:15632189) RGD PMID:15632189 NCBI chr14:1,059,125...1,073,131 JBrowse link
G F2r coagulation factor II (thrombin) receptor involved_in
acts_upstream_of_or_within
IEA
ISO
ISS
GO_REF:0000107
MGI:88380 (MGI:3810206|PMID:18398001)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:18398001 GO_REF:0000024 GO_REF:0000107 MGI:3810206 NCBI chr 2:26,869,343...26,885,856 JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:26,772,274...26,785,226 JBrowse link
G F2rl2 coagulation factor II (thrombin) receptor-like 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:26,972,054...26,977,098 JBrowse link
G F2rl3 F2R like thrombin or trypsin receptor 3 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr16:17,117,441...17,119,434 JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase involved_in IEP PMID:19383433 UniProt PMID:19383433 RGD:8553438 NCBI chr16:33,986,265...34,024,228 JBrowse link
G Iqgap2 IQ motif containing GTPase activating protein 2 involved_in ISO (PMID:12515716) RGD PMID:12515716 NCBI chr 2:26,894,836...27,170,270 JBrowse link
G Plek pleckstrin involved_in ISO (PMID:7782310)
(MGI:3844782|PMID:19190246)
RGD PMID:7782310 PMID:19190246 MGI:3844782 NCBI chr14:91,397,015...91,429,693 JBrowse link
negative regulation of thrombin-activated receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Met MET proto-oncogene, receptor tyrosine kinase involved_in ISO
IEA
(PMID:25198505)
GO_REF:0000107
RGD
Ensembl
PMID:25198505 GO_REF:0000107 NCBI chr 4:45,790,456...45,898,139 JBrowse link
G Snca synuclein alpha involved_in ISO (PMID:12239163) RGD PMID:12239163 NCBI chr 4:89,696,420...89,797,240 JBrowse link
G Stmn1 stathmin 1 involved_in ISO (PMID:25198505) RGD PMID:25198505 NCBI chr 5:146,680,757...146,687,154 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    signaling 7457
      signal transduction 6880
        G protein-coupled receptor signaling pathway 2333
          thrombin-activated receptor signaling pathway 11
            negative regulation of thrombin-activated receptor signaling pathway 3
            positive regulation of thrombin-activated receptor signaling pathway 0
            regulation of thrombin-activated receptor signaling pathway + 3
Path 2
Term Annotations click to browse term
  biological_process 19492
    biological regulation 13513
      regulation of biological process 12769
        regulation of cellular process 12271
          signal transduction 6880
            G protein-coupled receptor signaling pathway 2333
              thrombin-activated receptor signaling pathway 11
                negative regulation of thrombin-activated receptor signaling pathway 3
                positive regulation of thrombin-activated receptor signaling pathway 0
                regulation of thrombin-activated receptor signaling pathway + 3
paths to the root