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ONTOLOGY REPORT - ANNOTATIONS


Term:complement component C5a signaling pathway
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Accession:GO:0038178 term browser browse the term
Definition:A G protein-coupled receptor signaling pathway initiated by a C5a component of the complement pathway binding to a complement receptor, and ending with regulation of a downstream cellular process. C5a is a peptide derived from the C5 complement factor.
Synonyms:exact_synonym: complement component C5a-induced signaling pathway



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complement component C5a signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C5ar1 complement C5a receptor 1 involved_in
acts_upstream_of_or_within
ISO (PMID:10571060)
(MGI:51391|PMID:1401897)
RGD PMID:1401897 PMID:10571060 MGI:51391 NCBI chr 1:76,948,622...76,959,826 JBrowse link
G C5ar2 complement C5a receptor 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:76,930,381...76,945,432
Ensembl chr 1:76,930,383...76,959,517
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18734
    cellular process 17431
      signal transduction 6808
        G protein-coupled receptor signaling pathway 2217
          complement component C5a signaling pathway 2
Path 2
Term Annotations click to browse term
  biological_process 18734
    biological regulation 13314
      regulation of biological process 12594
        regulation of immune system process 1523
          regulation of immune response 882
            positive regulation of immune response 568
              activation of immune response 340
                immune response-activating signal transduction 261
                  immune response-activating cell surface receptor signaling pathway 260
                    complement receptor mediated signaling pathway 11
                      complement component C5a signaling pathway 2
paths to the root