Send us a Message

Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   


Term:complement component C5a signaling pathway
go back to main search page
Accession:GO:0038178 term browser browse the term
Definition:A series of molecular signals generated as a consequence of a the C5a component of the complement pathway binding to a complement receptor, and ending with regulation of a downstream cellular process. C5a is a peptide derived from the C5 complement factor.
Synonyms:exact_synonym: complement component C5a-induced signaling pathway

show annotations for term's descendants           Sort by:
complement component C5a signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C5ar1 complement C5a receptor 1 involved_in ISO (PMID:10571060) RGD PMID:10571060 NCBI chr 1:76,948,622...76,959,826 JBrowse link
G C5ar2 complement C5a receptor 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:76,930,381...76,945,432 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    cellular process 18342
      signal transduction 6880
        G protein-coupled receptor signaling pathway 2333
          complement component C5a signaling pathway 2
Path 2
Term Annotations click to browse term
  biological_process 19492
    biological regulation 13513
      regulation of biological process 12769
        regulation of immune system process 1531
          regulation of immune response 951
            positive regulation of immune response 631
              activation of immune response 402
                immune response-activating signal transduction 321
                  immune response-activating cell surface receptor signaling pathway 320
                    complement receptor mediated signaling pathway 13
                      complement component C5a signaling pathway 2
paths to the root