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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of G protein-coupled receptor signaling pathway
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Accession:GO:0045744 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway.
Synonyms:exact_synonym: down regulation of G-protein coupled receptor protein signaling pathway;   downregulation of G-protein coupled receptor protein signaling pathway;   negative regulation of G protein coupled receptor protein signaling pathway;   negative regulation of G protein coupled receptor protein signalling pathway;   negative regulation of GPCR protein signaling pathway;   negative regulation of GPCR protein signalling pathway
 narrow_synonym: inhibition of G-protein coupled receptor protein signaling pathway

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negative regulation of G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl5 C-C motif chemokine ligand 5 involved_in ISO (PMID:10734056) RGD PMID:10734056 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315 		JBrowse link
G Cry1 cryptochrome circadian regulator 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5567906|PMID:20852621)		 UniProt
RGD		 PMID:20852621 GO_REF:0000024 MGI:5567906 NCBI chr 7:24,534,593...24,634,098
Ensembl chr 7:24,534,615...24,634,097 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 IDA RGD PMID:1403099 RGD:632163 NCBI chr 1:219,536,220...219,544,329
Ensembl chr 1:219,536,220...219,544,328 		JBrowse link
G Grk3 G protein-coupled receptor kinase 3 IC RGD PMID:1403099 RGD:632163 NCBI chr12:49,626,871...49,750,389
Ensembl chr12:49,626,871...49,746,272 		JBrowse link
G Klk14 kallikrein related-peptidase 14 involved_in ISO (PMID:16885167) RGD PMID:16885167 NCBI chr 1:99,616,153...99,621,425
Ensembl chr 1:99,616,447...99,621,037 		JBrowse link
G Mgrn1 mahogunin ring finger 1 involved_in ISS
IEA
ISO
IBA		 GO_REF:0000024
GO_REF:0000107
(PMID:19737927)
PMID:21873635		 UniProt
Ensembl
RGD		 PMID:19737927, PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr10:10,832,573...10,881,999
Ensembl chr10:10,833,519...10,881,977 		JBrowse link
G Plek pleckstrin involved_in ISO (PMID:7782310) RGD PMID:7782310 NCBI chr14:100,151,518...100,184,192
Ensembl chr14:100,151,210...100,217,913 		JBrowse link
G Rgs12 regulator of G-protein signaling 12 IEP RGD PMID:9651375 RGD:69959 NCBI chr14:80,975,239...81,069,519
Ensembl chr14:80,975,322...81,053,906 		JBrowse link
G Rgs13 regulator of G-protein signaling 13 acts_upstream_of_or_within ISO (MGI:2385407|PMID:12193720) RGD PMID:12193720 MGI:2385407 NCBI chr13:60,970,172...61,004,260
Ensembl chr13:60,970,247...61,003,744 		JBrowse link
G Rgs14 regulator of G-protein signaling 14 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5009199|PMID:10926822)		 UniProt
RGD		 PMID:10926822 GO_REF:0000024 MGI:5009199 NCBI chr17:9,777,925...9,792,007
Ensembl chr17:9,777,842...9,792,007 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 involved_in IEP
ISO
IMP		 (MGI:3836877|PMID:19127022) RGD PMID:19127022, PMID:11968023, PMID:21798518 MGI:3836877, RGD:633858, RGD:7207364 NCBI chr13:60,846,458...60,849,061
Ensembl chr13:60,846,308...60,849,094 		JBrowse link
G Rgs4 regulator of G-protein signaling 4 IMP RGD PMID:21798518, PMID:9918533 RGD:7207364, RGD:7207376 NCBI chr13:88,054,817...88,061,108
Ensembl chr13:88,054,817...88,061,108 		JBrowse link
G Rnf157 ring finger protein 157 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:105,291,148...105,368,316
Ensembl chr10:105,293,490...105,368,242 		JBrowse link
G Rpgrip1l Rpgrip1-like involved_in ISO (PMID:19464661) RGD PMID:19464661 NCBI chr19:17,115,266...17,208,055
Ensembl chr19:17,115,412...17,208,055 		JBrowse link
G Rph3al rabphilin 3A-like (without C2 domains) acts_upstream_of_or_within ISO MGI:3051976 (MGI:3044444|PMID:15159548) RGD PMID:15159548 MGI:3044444 NCBI chr10:63,989,556...64,140,584
Ensembl chr10:63,989,644...64,108,554 		JBrowse link
G Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta involved_in ISO
ISS		 (PMID:21224381)
GO_REF:0000024		 RGD
UniProt		 PMID:21224381 GO_REF:0000024 NCBI chr 3:160,391,108...160,399,931
Ensembl chr 3:160,391,106...160,399,931 		JBrowse link
desensitization of G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gipr gastric inhibitory polypeptide receptor IDA RGD PMID:8928774 RGD:2312614 NCBI chr 1:80,063,047...80,073,223
Ensembl chr 1:80,063,049...80,073,223 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 involved_in
acts_upstream_of_or_within		 IC
IBA
ISO
IDA
IEA
IMP		 PMID:21873635
MGI:2180127|MGI:87937 (MGI:1337704|PMID:10338466), (MGI:84440|PMID:7761854)
PMID:18223549
GO_REF:0000107		 RGD
Ensembl		 PMID:7761854 PMID:10338466, PMID:1403099, PMID:21873635, PMID:18223549, PMID:30075183, PMID:17908240 GO_REF:0000107 MGI:1337704 MGI:84440, RGD:632163, RGD:13792537, RGD:8553863, RGD:13792694, RGD:7242040 NCBI chr 1:219,536,220...219,544,329
Ensembl chr 1:219,536,220...219,544,328 		JBrowse link
G Grk3 G protein-coupled receptor kinase 3 involved_in IC
IBA
IMP
IDA		 PMID:21873635 RGD
GO_Central		 PMID:1403099, PMID:21873635, PMID:8381966, PMID:20837135 RGD:632163, RGD:13792537, RGD:5685621, RGD:5685022 NCBI chr12:49,626,871...49,750,389
Ensembl chr12:49,626,871...49,746,272 		JBrowse link
G Grk4 G protein-coupled receptor kinase 4 IMP RGD PMID:15166006 RGD:1598508 NCBI chr14:81,261,708...81,339,516
Ensembl chr14:81,265,672...81,339,526 		JBrowse link
G Grk5 G protein-coupled receptor kinase 5 IMP RGD PMID:8626574, PMID:30075183 RGD:61618, RGD:13792694 NCBI chr 1:282,265,371...282,467,842
Ensembl chr 1:282,265,370...282,462,605 		JBrowse link
G Grk6 G protein-coupled receptor kinase 6 IDA
IMP		 RGD PMID:12810562, PMID:17908240 RGD:1299124, RGD:7242040 NCBI chr17:9,705,917...9,721,921
Ensembl chr17:9,703,453...9,721,574 		JBrowse link
G Grm5 glutamate metabotropic receptor 5 involved_in IDA PMID:12514208 UniProt PMID:12514208 RGD:728711 NCBI chr 1:151,207,846...151,785,038
Ensembl chr 1:151,439,409...151,783,392 		JBrowse link
G Ly6g6e lymphocyte antigen 6 family member G6E involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(MGI:5694852|PMID:26276394)		 RGD PMID:26276394, PMID:21873635 MGI:5694852, RGD:13792537 NCBI chr20:5,063,148...5,069,032
Ensembl chr20:5,067,330...5,068,624 		JBrowse link
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:9350980 RGD:9850278 NCBI chr 2:263,895,093...263,979,682
Ensembl chr 2:263,895,241...263,979,698 		JBrowse link
desensitization of G protein-coupled receptor signaling pathway by arrestin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenoceptor beta 2 involved_in ISO
ISS		 (PMID:15123695)
GO_REF:0000024		 RGD
HGNC-UCL		 PMID:15123695 GO_REF:0000024 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834 		JBrowse link
G Adrb3 adrenoceptor beta 3 NOT|involved_in ISO (PMID:15123695) RGD PMID:15123695 NCBI chr16:69,003,541...69,006,632
Ensembl chr16:69,003,868...69,006,632 		JBrowse link
G Arrb2 arrestin, beta 2 involved_in IMP
ISO		 (PMID:12582207) RGD PMID:12582207, PMID:20705669 RGD:5509896 NCBI chr10:57,040,252...57,048,045
Ensembl chr10:57,040,267...57,048,134 		JBrowse link
G protein-coupled receptor catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Becn2 beclin 2 involved_in
acts_upstream_of_or_within		 ISO (PMID:23954414)
UniProtKB:Q5JY77 (PMID:23954414)
MGI:5550535 (MGI:5528919|PMID:23954414)		 RGD PMID:23954414 MGI:5528919 NCBI chr13:93,971,720...93,974,467
Ensembl chr13:93,972,426...93,974,410 		JBrowse link
G Gprasp1 G protein-coupled receptor associated sorting protein 1 involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 GO_REF:0000024
UniProtKB:A8MW95 (PMID:23954414)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:23954414 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:106,306,795...106,313,904
Ensembl chr  X:106,306,795...106,313,853 		JBrowse link
G protein-coupled receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin involved_in ISO (PMID:10882736) RGD PMID:10882736 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259 		JBrowse link
G Arr3 arrestin 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:70,438,590...70,452,140
Ensembl chr  X:70,438,617...70,452,067 		JBrowse link
G Arrb1 arrestin, beta 1 involved_in IBA
ISO		 PMID:21873635
(PMID:10521508), (PMID:12582207)		 RGD PMID:10521508 PMID:12582207, PMID:21873635 RGD:13792537 NCBI chr 1:164,502,099...164,573,947
Ensembl chr 1:164,502,389...164,593,139 		JBrowse link
G Arrb2 arrestin, beta 2 involved_in IBA
ISO		 PMID:21873635
(PMID:10644702), (PMID:12582207)		 RGD PMID:10644702 PMID:12582207, PMID:21873635 RGD:13792537 NCBI chr10:57,040,252...57,048,045
Ensembl chr10:57,040,267...57,048,134 		JBrowse link
G Calca calcitonin-related polypeptide alpha involved_in ISO (PMID:10882736) RGD PMID:10882736 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911 		JBrowse link
G Dnm1 dynamin 1 IMP RGD PMID:14709338 RGD:9685157 NCBI chr 3:11,338,081...11,382,043
Ensembl chr 3:11,338,083...11,382,043 		JBrowse link
G Dnm2 dynamin 2 IMP RGD PMID:14709338 RGD:9685157 NCBI chr 8:22,458,869...22,540,649
Ensembl chr 8:22,458,899...22,540,524 		JBrowse link
G Drd2 dopamine receptor D2 IDA RGD PMID:14617818 RGD:1581465 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642 		JBrowse link
G Drd3 dopamine receptor D3 involved_in IDA
ISO		 (PMID:18424554) RGD PMID:18424554, PMID:14617818 RGD:1581465 NCBI chr11:61,819,102...61,883,223
Ensembl chr11:61,822,077...61,874,327 		JBrowse link
G Grk4 G protein-coupled receptor kinase 4 IMP RGD PMID:12519791 RGD:1304268 NCBI chr14:81,261,708...81,339,516
Ensembl chr14:81,265,672...81,339,526 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B involved_in ISO (MGI:4821070|PMID:17325130) RGD PMID:17325130 MGI:4821070 NCBI chr 8:89,113,984...89,130,830
Ensembl chr 8:89,129,453...89,130,991 		JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B involved_in IEA
ISO		 GO_REF:0000107
(MGI:4821070|PMID:17325130)		 Ensembl
RGD		 PMID:17325130 GO_REF:0000107 MGI:4821070 NCBI chr 9:93,112,781...93,130,135
Ensembl chr 9:93,112,805...93,125,014 		JBrowse link
G Pld2 phospholipase D2 acts_upstream_of_or_within ISO (MGI:3042801|PMID:14718562) RGD PMID:14718562 MGI:3042801 NCBI chr10:57,161,921...57,181,148
Ensembl chr10:57,163,174...57,179,730 		JBrowse link
G Sag S-antigen visual arrestin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:94,926,901...94,972,162
Ensembl chr 9:94,928,489...94,972,027 		JBrowse link
inhibitory G protein-coupled receptor phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk2b calcium/calmodulin-dependent protein kinase II beta acts_upstream_of_or_within ISO (MGI:4352609|PMID:19332541) RGD PMID:19332541 MGI:4352609 NCBI chr14:86,208,876...86,297,727
Ensembl chr14:86,208,901...86,297,652 		JBrowse link
negative regulation of adenosine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase involved_in IBA
ISO		 PMID:21873635
(PMID:16670267)		 RGD PMID:16670267, PMID:21873635 RGD:13792537 NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947 		JBrowse link
negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrdc3 arrestin domain containing 3 acts_upstream_of_or_within ISO MGI:3877613 (MGI:5302794|PMID:21982743) RGD PMID:21982743 MGI:5302794 NCBI chr 2:8,732,907...8,745,445
Ensembl chr 2:8,732,932...8,743,069 		JBrowse link
negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 involved_in ISO (PMID:17242280) RGD PMID:17242280 NCBI chr13:50,091,644...50,153,808
Ensembl chr13:50,091,430...50,153,823 		JBrowse link
G Gnai2 G protein subunit alpha i2 IDA RGD PMID:12631586 RGD:13508593 NCBI chr 8:116,370,730...116,391,337
Ensembl chr 8:116,370,744...116,391,307 		JBrowse link
G Pde4b phosphodiesterase 4B involved_in IEA
ISO		 GO_REF:0000107
(MGI:5286798|PMID:21670503)		 Ensembl
RGD		 PMID:21670503 GO_REF:0000107 MGI:5286798 NCBI chr 5:121,759,236...122,136,814
Ensembl chr 5:121,952,977...122,136,814 		JBrowse link
negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aplp1 amyloid beta precursor like protein 1 involved_in ISO (PMID:16531006) RGD PMID:16531006 NCBI chr 1:88,897,525...88,908,750
Ensembl chr 1:88,897,532...88,908,750 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 IMP RGD PMID:30075183 RGD:13792694 NCBI chr 1:219,536,220...219,544,329
Ensembl chr 1:219,536,220...219,544,328 		JBrowse link
G Grk5 G protein-coupled receptor kinase 5 IMP RGD PMID:30075183 RGD:13792694 NCBI chr 1:282,265,371...282,467,842
Ensembl chr 1:282,265,370...282,462,605 		JBrowse link
G Mrap melanocortin 2 receptor accessory protein involved_in ISO (PMID:19329486) RGD PMID:19329486 NCBI chr11:30,904,733...30,915,225
Ensembl chr11:30,904,733...30,915,225 		JBrowse link
G Mrap2 melanocortin 2 receptor accessory protein 2 involved_in ISO (PMID:19329486) RGD PMID:19329486 NCBI chr 8:94,801,336...94,858,192
Ensembl chr 8:94,801,336...94,857,443 		JBrowse link
G Oprl1 opioid related nociceptin receptor 1 IDA RGD PMID:15748148 RGD:9835006 NCBI chr 3:177,223,779...177,231,663
Ensembl chr 3:177,225,737...177,231,663 		JBrowse link
G Oprm1 opioid receptor, mu 1 IDA RGD PMID:15748148 RGD:9835006 NCBI chr 1:43,454,803...43,704,948
Ensembl chr 1:43,454,803...43,704,948 		JBrowse link
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:9013884 RGD:9850263 NCBI chr 2:263,895,093...263,979,682
Ensembl chr 2:263,895,241...263,979,698 		JBrowse link
G Sstr4 somatostatin receptor 4 IDA RGD PMID:8175684 RGD:2325010 NCBI chr 3:142,739,781...142,741,644
Ensembl chr 3:142,739,781...142,741,644 		JBrowse link
negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rgs2 regulator of G-protein signaling 2 involved_in ISO (MGI:5009116|PMID:21291891) RGD PMID:21291891 MGI:5009116 NCBI chr13:60,846,458...60,849,061
Ensembl chr13:60,846,308...60,849,094 		JBrowse link
negative regulation of G protein-coupled receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Necab2 N-terminal EF-hand calcium binding protein 2 involved_in ISO (PMID:17689978) RGD PMID:17689978 NCBI chr19:52,086,325...52,112,633
Ensembl chr19:52,086,325...52,112,629 		JBrowse link
G Ubqln2 ubiquilin 2 involved_in ISO (PMID:18199683) RGD PMID:18199683 NCBI chr  X:18,723,313...18,726,732
Ensembl chr  X:18,723,341...18,726,732 		JBrowse link
negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bicd1 BICD cargo adaptor 1 involved_in IMP
ISO		 PMID:20164183
(MGI:4887309|PMID:20164183)		 RGD PMID:20164183, PMID:20164183 MGI:4887309, RGD:8693367 NCBI chr 4:184,018,845...184,167,628
Ensembl chr 4:184,019,087...184,165,540 		JBrowse link
negative regulation of thrombin-activated receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Met MET proto-oncogene, receptor tyrosine kinase involved_in ISO
IEA		 (PMID:25198505)
GO_REF:0000107		 RGD
Ensembl		 PMID:25198505 GO_REF:0000107 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665 		JBrowse link
G Snca synuclein alpha involved_in ISO (PMID:12239163) RGD PMID:12239163 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285 		JBrowse link
G Stmn1 stathmin 1 involved_in ISO (PMID:25198505) RGD PMID:25198505 NCBI chr 5:152,680,412...152,686,807
Ensembl chr 5:152,680,407...152,686,806 		JBrowse link
positive regulation of G protein-coupled receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apela apelin receptor early endogenous ligand involved_in ISO (PMID:25639753) RGD PMID:25639753 NCBI chr16:26,582,103...26,583,828 JBrowse link
G Apln apelin involved_in ISO
IDA		 (PMID:11359874)
(MGI:5902690|PMID:11359874)		 RGD PMID:11359874, PMID:11359874 MGI:5902690, RGD:12907555 NCBI chr  X:134,856,719...134,866,210
Ensembl chr  X:134,856,726...134,866,210 		JBrowse link
G App amyloid beta precursor protein involved_in ISO (PMID:18723082) RGD PMID:18723082 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858 		JBrowse link
positive regulation of inhibitory G protein-coupled receptor phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aplnr apelin receptor involved_in ISS
ISO		 GO_REF:0000024
(PMID:25639753)		 UniProt
RGD		 PMID:25639753 GO_REF:0000024 NCBI chr 3:72,540,538...72,544,183
Ensembl chr 3:72,540,538...72,544,182 		JBrowse link
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:15937517 RGD:10043344 NCBI chr 2:263,895,093...263,979,682
Ensembl chr 2:263,895,241...263,979,698 		JBrowse link
prostaglandin receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:15937517 RGD:10043344 NCBI chr 2:263,895,093...263,979,682
Ensembl chr 2:263,895,241...263,979,698 		JBrowse link
termination of G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rgs12 regulator of G-protein signaling 12 IDA RGD PMID:11130074 RGD:7207399 NCBI chr14:80,975,239...81,069,519
Ensembl chr14:80,975,322...81,053,906 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19612
    cellular process 18457
      signal transduction 6956
        G protein-coupled receptor signaling pathway 2377
          negative regulation of G protein-coupled receptor signaling pathway 62
            G protein-coupled receptor catabolic process 2
            desensitization of G protein-coupled receptor signaling pathway + 31
            negative regulation of adenosine receptor signaling pathway 1
            negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway + 13
            negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process 1
            negative regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway 0
            negative regulation of angiotensin-activated signaling pathway 0
            negative regulation of beta1-adrenergic receptor activity 0
            negative regulation of octopamine or tyramine signaling pathway + 0
            negative regulation of opioid receptor signaling pathway + 0
            negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway + 1
            negative regulation of proteinase activated receptor activity 0
            negative regulation of thrombin-activated receptor signaling pathway 3
            suppression by symbiont of host G protein-coupled receptor signal transduction 0
            termination of G protein-coupled receptor signaling pathway 1
Path 2
Term Annotations click to browse term
  biological_process 19612
    biological regulation 13583
      regulation of biological process 12857
        regulation of cellular process 12354
          regulation of cell communication 3507
            negative regulation of cell communication 1400
              negative regulation of signal transduction 1264
                negative regulation of G protein-coupled receptor signaling pathway 62
                  G protein-coupled receptor catabolic process 2
                  desensitization of G protein-coupled receptor signaling pathway + 31
                  negative regulation of adenosine receptor signaling pathway 1
                  negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway + 13
                  negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process 1
                  negative regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway 0
                  negative regulation of angiotensin-activated signaling pathway 0
                  negative regulation of beta1-adrenergic receptor activity 0
                  negative regulation of octopamine or tyramine signaling pathway + 0
                  negative regulation of opioid receptor signaling pathway + 0
                  negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway + 1
                  negative regulation of proteinase activated receptor activity 0
                  negative regulation of thrombin-activated receptor signaling pathway 3
                  suppression by symbiont of host G protein-coupled receptor signal transduction 0
                  termination of G protein-coupled receptor signaling pathway 1
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