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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of G protein-coupled receptor signaling pathway
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Accession:GO:0045744 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway.
Synonyms:exact_synonym: down regulation of G-protein coupled receptor protein signaling pathway;   downregulation of G-protein coupled receptor protein signaling pathway;   negative regulation of G protein coupled receptor protein signaling pathway;   negative regulation of G protein coupled receptor protein signalling pathway;   negative regulation of GPCR protein signaling pathway;   negative regulation of GPCR protein signalling pathway
 narrow_synonym: inhibition of G-protein coupled receptor protein signaling pathway


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negative regulation of G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenoceptor beta 2 involved_in ISO
IEA		 (PMID:15123695)
GO_REF:0000107		 RGD
Ensembl		 PMID:15123695 GO_REF:0000107 NCBI chr18:57,912,760...57,914,802
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Adrb3 adrenoceptor beta 3 NOT|involved_in ISO (PMID:15123695) RGD PMID:15123695 NCBI chr16:71,544,603...71,547,410
Ensembl chr16:64,841,788...64,844,552 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 involved_in ISO (PMID:10734056) RGD PMID:10734056 NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Cry1 cryptochrome circadian regulator 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20852621)		 UniProt
RGD		 PMID:20852621 GO_REF:0000024 NCBI chr 7:20,417,526...20,481,791
Ensembl chr 7:18,529,823...18,594,091 		JBrowse link
G Klk14 kallikrein related-peptidase 14 involved_in ISO (PMID:16885167) RGD PMID:16885167 NCBI chr 1:94,123,131...94,137,239
Ensembl chr 1:94,131,998...94,137,240 		JBrowse link
G Mgrn1 mahogunin ring finger 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:10,638,881...10,688,332
Ensembl chr10:10,638,880...10,688,315 		JBrowse link
G Plek pleckstrin involved_in ISO (PMID:7782310) RGD PMID:7782310 NCBI chr14:95,598,650...95,631,326
Ensembl chr14:91,397,019...91,454,131 		JBrowse link
G Rgs12 regulator of G-protein signaling 12 IEP RGD PMID:9651375 RGD:69959 NCBI chr14:79,940,561...80,048,637
Ensembl chr14:75,715,934...75,794,596 		JBrowse link
G Rgs13 regulator of G-protein signaling 13 acts_upstream_of_or_within ISO (PMID:12193720) RGD PMID:12193720 NCBI chr13:58,472,604...58,505,922
Ensembl chr13:55,922,395...55,955,648 		JBrowse link
G Rgs14 regulator of G-protein signaling 14 involved_in ISS
ISO		 GO_REF:0000024
(PMID:10926822)		 UniProt
RGD		 PMID:10926822 GO_REF:0000024 NCBI chr17:9,254,112...9,268,233
Ensembl chr17:9,249,019...9,263,104 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 involved_in IEP
ISO
IMP		 (PMID:19127022) RGD PMID:19127022 PMID:11968023 PMID:21798518 RGD:633858, RGD:7207364 NCBI chr13:58,350,063...58,352,666
Ensembl chr13:55,798,829...55,802,385 		JBrowse link
G Rgs4 regulator of G-protein signaling 4 IMP RGD PMID:21798518 PMID:9918533 RGD:7207364, RGD:7207376 NCBI chr13:84,469,593...84,475,884
Ensembl chr13:81,936,775...81,943,068 		JBrowse link
G Rgs7 regulator of G-protein signaling 7 involved_in ISO
ISS		 (PMID:36996198)
GO_REF:0000024		 RGD
UniProt		 PMID:36996198 GO_REF:0000024 NCBI chr13:86,979,269...87,408,834
Ensembl chr13:86,979,279...87,408,888 		JBrowse link
G Rpgrip1l Rpgrip1-like involved_in ISO (PMID:19464661) RGD PMID:19464661 NCBI chr19:31,865,050...31,957,930
Ensembl chr19:15,692,150...15,785,083 		JBrowse link
G Rph3al rabphilin 3A-like (without C2 domains) acts_upstream_of_or_within ISO MGI:3051976 (PMID:15159548) RGD PMID:15159548 NCBI chr10:61,188,288...61,331,591
Ensembl chr10:60,690,031...60,801,883 		JBrowse link
G test test1 IDA
IC		 RGD PMID:1403099 PMID:1403099 RGD:632163, RGD:632163
G Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta involved_in ISO
IEA
ISS		 (PMID:21224381)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:21224381 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:173,078,904...173,101,508
Ensembl chr 3:152,659,651...152,682,105 		JBrowse link
desensitization of G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin, beta 2 involved_in ISO (PMID:12582207) RGD PMID:12582207 NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Gipr gastric inhibitory polypeptide receptor IDA RGD PMID:8928774 RGD:2312614 NCBI chr 1:78,804,287...78,814,462
Ensembl chr 1:78,805,593...78,814,462 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 acts_upstream_of_or_within
involved_in		 IMP
ISO
IBA
IEA
IDA		 MGI:2180127|MGI:87937 (PMID:10338466), (PMID:7761854)
GO_REF:0000033
GO_REF:0000107
(PMID:15102938)
PMID:18223549		 RGD
GO_Central
Ensembl		 PMID:7761854 PMID:10338466 PMID:15102938 PMID:17908240 PMID:18223549 More... GO_REF:0000033 GO_REF:0000107, RGD:7242040, RGD:8553863, RGD:13792694 NCBI chr 1:211,010,259...211,031,013
Ensembl chr 1:201,581,480...201,601,582 		JBrowse link
G Grk3 G protein-coupled receptor kinase 3 involved_in IDA
IBA
IMP		 GO_REF:0000033 GO_Central
RGD		 PMID:20837135 PMID:8381966 GO_REF:0000033, RGD:5685022, RGD:5685621 NCBI chr12:49,285,228...49,395,803
Ensembl chr12:43,624,897...43,731,262 		JBrowse link
G Grk4 G protein-coupled receptor kinase 4 IMP RGD PMID:15166006 RGD:1598508 NCBI chr14:75,998,554...76,080,808
Ensembl chr14:76,006,218...76,080,693 		JBrowse link
G Grk5 G protein-coupled receptor kinase 5 IMP RGD PMID:8626574 PMID:30075183 RGD:61618, RGD:13792694 NCBI chr 1:270,014,314...270,208,294
Ensembl chr 1:260,028,242...260,218,701 		JBrowse link
G Grk6 G protein-coupled receptor kinase 6 IDA
IMP		 RGD PMID:12810562 PMID:17908240 RGD:1299124, RGD:7242040 NCBI chr17:9,182,160...9,198,380
Ensembl chr17:9,177,019...9,192,644 		JBrowse link
G Grm5 glutamate metabotropic receptor 5 involved_in IDA PMID:12514208 UniProt PMID:12514208 RGD:728711 NCBI chr 1:150,722,711...151,297,585
Ensembl chr 1:141,312,368...141,882,274 		JBrowse link
G Ly6g6e lymphocyte antigen 6 family member G6E involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:26276394)		 GO_Central
RGD		 PMID:26276394 GO_REF:0000033 NCBI chr20:3,744,999...3,749,867
Ensembl chr20:3,744,999...3,750,849 		JBrowse link
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:9350980 RGD:9850278 NCBI chr 2:249,264,985...249,409,966
Ensembl chr 2:246,606,183...246,684,434 		JBrowse link
G test test1 TAS
IC		 RGD PMID:1403099 PMID:1403099 RGD:632163, RGD:632163
G protein-coupled receptor catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Becn2 beclin 2 involved_in
acts_upstream_of_or_within		 ISO (PMID:23954414)
MGI:5550535 (PMID:23954414)
UniProtKB:Q5JY77 (PMID:23954414)		 RGD PMID:23954414 NCBI chr13:87,842,980...87,892,410
Ensembl chr13:87,844,531...87,845,787 		JBrowse link
G Gprasp1 G protein-coupled receptor associated sorting protein 1 involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 GO_REF:0000024
UniProtKB:A8MW95 (PMID:23954414)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:23954414 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:103,556,493...103,564,275
Ensembl chr  X:98,709,841...98,772,851 		JBrowse link
G protein-coupled receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin involved_in ISO (PMID:10882736) RGD PMID:10882736 NCBI chr 1:174,164,178...174,182,372
Ensembl chr 1:164,745,466...164,747,654 		JBrowse link
G Arrb1 arrestin, beta 1 involved_in ISO
IBA		 (PMID:10521508), (PMID:12582207)
GO_REF:0000033		 RGD
GO_Central		 PMID:10521508 PMID:12582207 GO_REF:0000033 NCBI chr 1:163,249,654...163,321,711
Ensembl chr 1:153,838,078...153,904,061 		JBrowse link
G Arrb2 arrestin, beta 2 involved_in ISO
IBA
IEA		 (PMID:10644702), (PMID:12582207)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:10644702 PMID:12582207 GO_REF:0000033 GO_REF:0000107 NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Calca calcitonin-related polypeptide alpha involved_in ISO (PMID:10882736) RGD PMID:10882736 NCBI chr 1:178,312,636...178,317,588
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Dnm1 dynamin 1 IMP RGD PMID:14709338 RGD:9685157 NCBI chr 3:36,002,535...36,055,220
Ensembl chr 3:15,604,784...15,648,538 		JBrowse link
G Dnm2 dynamin 2 IMP RGD PMID:14709338 RGD:9685157 NCBI chr 8:28,254,344...28,336,297
Ensembl chr 8:19,978,400...20,060,157 		JBrowse link
G Drd2 dopamine receptor D2 IDA RGD PMID:14617818 RGD:1581465 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd3 dopamine receptor D3 involved_in IDA
IEA
ISO		 GO_REF:0000107
(PMID:18424554)		 Ensembl
RGD		 PMID:18424554 PMID:14617818 GO_REF:0000107, RGD:1581465 NCBI chr11:70,385,586...70,437,793
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G ENSRNOG00000063241 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr13:26,511,609...26,513,494 JBrowse link
G Grk4 G protein-coupled receptor kinase 4 IMP RGD PMID:12519791 RGD:1304268 NCBI chr14:75,998,554...76,080,808
Ensembl chr14:76,006,218...76,080,693 		JBrowse link
G Gtf2h2 general transcription factor IIH subunit 2 involved_in ISO (PMID:15775968) RGD PMID:15775968 NCBI chr 2:31,623,752...31,652,697
Ensembl chr 2:31,624,678...31,652,592 		JBrowse link
G Pld2 phospholipase D2 acts_upstream_of_or_within ISO (PMID:14718562) RGD PMID:14718562 NCBI chr10:55,754,957...55,772,819
Ensembl chr10:55,256,359...55,272,808 		JBrowse link
G Sag S-antigen visual arrestin involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:88,467,797...88,508,821
Ensembl chr 9:88,469,376...88,508,820 		JBrowse link
inhibitory G protein-coupled receptor phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk2b calcium/calmodulin-dependent protein kinase II beta acts_upstream_of_or_within ISO (PMID:19332541) RGD PMID:19332541 NCBI chr14:85,059,166...85,148,121
Ensembl chr14:80,845,238...80,933,994 		JBrowse link
negative regulation of adenosine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase involved_in ISO
IEA
IBA		 (PMID:16670267)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:16670267 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrdc3 arrestin domain containing 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3877613 (PMID:21982743)		 Ensembl
RGD		 PMID:21982743 GO_REF:0000107 NCBI chr 2:12,873,202...12,885,716
Ensembl chr 2:11,137,460...11,149,978 		JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 involved_in ISO (PMID:17242280) RGD PMID:17242280 NCBI chr13:47,708,157...47,807,389
Ensembl chr13:45,156,146...45,255,246 		JBrowse link
G Crtc3 CREB regulated transcription coactivator 3 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:21164481)
GO_REF:0000033		 RGD
GO_Central		 PMID:21164481 GO_REF:0000033 NCBI chr 1:143,962,038...144,064,324
Ensembl chr 1:134,554,696...134,655,500 		JBrowse link
G Gnai2 G protein subunit alpha i2 IDA RGD PMID:12631586 RGD:13508593 NCBI chr 8:117,167,045...117,187,652
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
G Pde4b phosphodiesterase 4B involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 5:122,028,956...122,598,267
Ensembl chr 5:116,799,971...117,367,696 		JBrowse link
negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aplp1 amyloid beta precursor like protein 1 involved_in ISO (PMID:16531006) RGD PMID:16531006 NCBI chr 1:94,824,330...94,834,705
Ensembl chr 1:85,696,882...85,707,155 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 IMP RGD PMID:30075183 RGD:13792694 NCBI chr 1:211,010,259...211,031,013
Ensembl chr 1:201,581,480...201,601,582 		JBrowse link
G Grk5 G protein-coupled receptor kinase 5 IMP RGD PMID:30075183 RGD:13792694 NCBI chr 1:270,014,314...270,208,294
Ensembl chr 1:260,028,242...260,218,701 		JBrowse link
G Mgrn1 mahogunin ring finger 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:19737927)		 UniProt
Ensembl
RGD		 PMID:19737927 GO_REF:0000024 GO_REF:0000107 NCBI chr10:10,638,881...10,688,332
Ensembl chr10:10,638,880...10,688,315 		JBrowse link
G Mrap melanocortin 2 receptor accessory protein involved_in ISO (PMID:19329486) RGD PMID:19329486 NCBI chr11:43,477,382...43,489,118
Ensembl chr11:29,992,034...30,003,024 		JBrowse link
G Mrap2 melanocortin 2 receptor accessory protein 2 involved_in ISO (PMID:19329486) RGD PMID:19329486 NCBI chr 8:88,088,293...88,144,636
Ensembl chr 8:88,088,272...88,143,886 		JBrowse link
G Oprl1 opioid related nociceptin receptor 1 IDA RGD PMID:15748148 RGD:9835006 NCBI chr 3:189,209,495...189,225,406
Ensembl chr 3:168,834,003...168,839,920 		JBrowse link
G Oprm1 opioid receptor, mu 1 IDA RGD PMID:15748148 RGD:9835006 NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Pde2a phosphodiesterase 2A involved_in IEA
ISO		 GO_REF:0000107
(PMID:19252089)		 Ensembl
RGD		 PMID:19252089 GO_REF:0000107 NCBI chr 1:165,235,623...165,327,466
Ensembl chr 1:155,813,180...155,915,434 		JBrowse link
G Pde3a phosphodiesterase 3A involved_in ISO (PMID:19252089) RGD PMID:19252089 NCBI chr 4:175,904,276...176,170,531
Ensembl chr 4:174,172,868...174,438,274 		JBrowse link
G Pde4d phosphodiesterase 4D involved_in IEA
ISO		 GO_REF:0000107
(PMID:19252089), (PMID:20819076)		 Ensembl
RGD		 PMID:19252089 PMID:20819076 GO_REF:0000107 NCBI chr 2:41,748,337...43,262,567
Ensembl chr 2:40,019,933...41,525,884 		JBrowse link
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:9013884 RGD:9850263 NCBI chr 2:249,264,985...249,409,966
Ensembl chr 2:246,606,183...246,684,434 		JBrowse link
G Sstr4 somatostatin receptor 4 IDA RGD PMID:8175684 RGD:2325010 NCBI chr 3:156,307,992...156,309,855
Ensembl chr 3:135,854,826...135,856,689 		JBrowse link
negative regulation of angiotensin-activated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp3ca protein phosphatase 3 catalytic subunit alpha involved_in ISO (PMID:30718414) RGD PMID:30718414 NCBI chr 2:227,839,058...228,113,560
Ensembl chr 2:225,165,766...225,438,974 		JBrowse link
negative regulation of chemokine-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl5 C-C motif chemokine ligand 5 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Mir101-2 microRNA 101-2 involved_in ISO (PMID:27693460) RGD PMID:27693460 NCBI chr 1:226,860,371...226,860,467
Ensembl chr 1:226,860,371...226,860,467 		JBrowse link
G Mir101a microRNA 101a involved_in ISO (PMID:27693460) RGD PMID:27693460 NCBI chr 5:115,966,332...115,966,406
Ensembl chr 5:115,966,328...115,966,410 		JBrowse link
G Mir20a microRNA 20a involved_in ISO (PMID:28972028) RGD PMID:28972028 NCBI chr15:98,588,303...98,588,387
Ensembl chr15:92,181,084...92,181,168 		JBrowse link
G Padi2 peptidyl arginine deiminase 2 involved_in ISO
IEA		 (PMID:18645041)
GO_REF:0000107		 RGD
Ensembl		 PMID:18645041 GO_REF:0000107 NCBI chr 5:158,492,087...158,534,662
Ensembl chr 5:153,209,053...153,251,632 		JBrowse link
G Rnf113a1 ring finger protein 113A1 involved_in ISO (PMID:28978524) RGD PMID:28978524 NCBI chr  X:121,293,621...121,294,844
Ensembl chr  X:116,427,684...116,433,762 		JBrowse link
G Robo1 roundabout guidance receptor 1 involved_in ISO (PMID:18829537) RGD PMID:18829537 NCBI chr11:24,067,869...25,108,694
Ensembl chr11:10,580,908...11,620,203 		JBrowse link
G Sh2b3 SH2B adaptor protein 3 involved_in ISO
IEA		 (PMID:15337790)
GO_REF:0000107		 RGD
Ensembl		 PMID:15337790 GO_REF:0000107 NCBI chr12:40,391,755...40,414,336
Ensembl chr12:34,731,911...34,753,616 		JBrowse link
G Slit2 slit guidance ligand 2 involved_in ISO
IEA		 (PMID:18829537)
GO_REF:0000107		 RGD
Ensembl		 PMID:18829537 GO_REF:0000107 NCBI chr14:66,829,661...67,168,517
Ensembl chr14:62,617,067...62,955,948 		JBrowse link
G Slit3 slit guidance ligand 3 involved_in ISO
IEA		 (PMID:18829537)
GO_REF:0000107		 RGD
Ensembl		 PMID:18829537 GO_REF:0000107 NCBI chr10:20,075,929...20,660,704
Ensembl chr10:19,571,684...20,156,634 		JBrowse link
negative regulation of dopamine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 acts_upstream_of_or_within ISO MGI:94925|MGI:99578 (PMID:12097513) RGD PMID:12097513 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd3 dopamine receptor D3 acts_upstream_of_or_within ISO MGI:94924|MGI:99578 (PMID:12097513) RGD PMID:12097513 NCBI chr11:70,385,586...70,437,793
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G Palm paralemmin involved_in ISO
IEA		 (PMID:16386234)
GO_REF:0000107		 RGD
Ensembl		 PMID:16386234 GO_REF:0000107 NCBI chr 7:10,537,252...10,563,346
Ensembl chr 7:9,886,643...9,912,555 		JBrowse link
G Rgs4 regulator of G-protein signaling 4 IDA RGD PMID:21896332 RGD:13524519 NCBI chr13:84,469,593...84,475,884
Ensembl chr13:81,936,775...81,943,068 		JBrowse link
negative regulation of G protein-coupled receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Necab2 N-terminal EF-hand calcium binding protein 2 involved_in ISO
IEA		 (PMID:17689978)
GO_REF:0000107		 RGD
Ensembl		 PMID:17689978 GO_REF:0000107 NCBI chr19:47,501,351...47,527,722
Ensembl chr19:47,501,302...47,527,684 		JBrowse link
G Ubqln2 ubiquilin 2 involved_in ISO (PMID:18199683) RGD PMID:18199683 NCBI chr  X:21,228,809...21,232,228
Ensembl chr  X:17,853,114...17,856,505 		JBrowse link
negative regulation of opioid receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin, beta 2 IDA RGD PMID:34919270 RGD:401938593 NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bicd1 BICD cargo adaptor 1 involved_in IMP
ISO		 PMID:20164183
(PMID:20164183)		 RGD PMID:20164183 PMID:20164183 RGD:8693367 NCBI chr 4:182,479,071...182,631,504
Ensembl chr 4:182,479,071...182,627,434 		JBrowse link
G Inpp5a inositol polyphosphate-5-phosphatase A involved_in ISS
ISO		 GO_REF:0000024
(PMID:26051944)		 UniProt
RGD		 PMID:26051944 GO_REF:0000024 NCBI chr 1:194,190,086...194,380,429
Ensembl chr 1:194,190,393...194,380,428 		JBrowse link
negative regulation of thrombin-activated receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Met MET proto-oncogene, receptor tyrosine kinase involved_in ISO
IEA		 (PMID:25198505)
GO_REF:0000107		 RGD
Ensembl		 PMID:25198505 GO_REF:0000107 NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Plek pleckstrin involved_in ISO (PMID:7559487) RGD PMID:7559487 NCBI chr14:95,598,650...95,631,326
Ensembl chr14:91,397,019...91,454,131 		JBrowse link
G Snca synuclein alpha involved_in ISO
IEA		 (PMID:12239163)
GO_REF:0000107		 RGD
Ensembl		 PMID:12239163 GO_REF:0000107 NCBI chr 4:91,026,474...91,127,444
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Stmn1 stathmin 1 involved_in ISO (PMID:25198505) RGD PMID:25198505 NCBI chr 5:151,964,308...151,970,843
Ensembl chr 5:146,681,436...146,687,154 		JBrowse link
positive regulation of G protein-coupled receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apela apelin receptor early endogenous ligand involved_in ISO (PMID:25639753) RGD PMID:25639753 NCBI chr16:24,694,356...24,703,466
Ensembl chr16:24,694,324...24,703,465 		JBrowse link
G Apln apelin involved_in ISO
IDA		 (PMID:11359874) RGD PMID:11359874 PMID:11359874 RGD:12907555 NCBI chr  X:132,058,739...132,091,518
Ensembl chr  X:127,203,823...127,213,391 		JBrowse link
G Aplnr apelin receptor involved_in ISO (PMID:25639753) RGD PMID:25639753 NCBI chr 3:90,624,055...90,627,700
Ensembl chr 3:70,217,385...70,221,050 		JBrowse link
G App amyloid beta precursor protein involved_in ISO (PMID:18723082) RGD PMID:18723082 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
positive regulation of inhibitory G protein-coupled receptor phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:15937517 RGD:10043344 NCBI chr 2:249,264,985...249,409,966
Ensembl chr 2:246,606,183...246,684,434 		JBrowse link
prostaglandin receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:15937517 RGD:10043344 NCBI chr 2:249,264,985...249,409,966
Ensembl chr 2:246,606,183...246,684,434 		JBrowse link
termination of G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rgs12 regulator of G-protein signaling 12 IDA RGD PMID:11130074 RGD:7207399 NCBI chr14:79,940,561...80,048,637
Ensembl chr14:75,715,934...75,794,596 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20553
    cellular process 19543
      signal transduction 7262
        G protein-coupled receptor signaling pathway 2462
          negative regulation of G protein-coupled receptor signaling pathway 78
            G protein-coupled receptor catabolic process 2
            desensitization of G protein-coupled receptor signaling pathway + 29
            negative regulation of adenosine receptor signaling pathway 1
            negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway + 18
            negative regulation of angiotensin-activated signaling pathway 1
            negative regulation of chemokine-mediated signaling pathway + 10
            negative regulation of dopamine receptor signaling pathway + 4
            negative regulation of octopamine or tyramine signaling pathway + 0
            negative regulation of opioid receptor signaling pathway + 1
            negative regulation of opsin-mediated signaling pathway + 0
            negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway + 2
            negative regulation of thrombin-activated receptor signaling pathway 4
            termination of G protein-coupled receptor signaling pathway 1
Path 2
Term Annotations click to browse term
  biological_process 20553
    biological regulation 13833
      regulation of biological process 13387
        signaling 7822
          signal transduction 7262
            regulation of signal transduction 3281
              regulation of G protein-coupled receptor signaling pathway 167
                negative regulation of G protein-coupled receptor signaling pathway 78
                  G protein-coupled receptor catabolic process 2
                  desensitization of G protein-coupled receptor signaling pathway + 29
                  negative regulation of adenosine receptor signaling pathway 1
                  negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway + 18
                  negative regulation of angiotensin-activated signaling pathway 1
                  negative regulation of chemokine-mediated signaling pathway + 10
                  negative regulation of dopamine receptor signaling pathway + 4
                  negative regulation of octopamine or tyramine signaling pathway + 0
                  negative regulation of opioid receptor signaling pathway + 1
                  negative regulation of opsin-mediated signaling pathway + 0
                  negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway + 2
                  negative regulation of thrombin-activated receptor signaling pathway 4
                  termination of G protein-coupled receptor signaling pathway 1
paths to the root