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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of G protein-coupled receptor signaling pathway
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Accession:GO:0045744 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway.
Synonyms:exact_synonym: down regulation of G-protein coupled receptor protein signaling pathway;   downregulation of G-protein coupled receptor protein signaling pathway;   negative regulation of G protein coupled receptor protein signaling pathway;   negative regulation of G protein coupled receptor protein signalling pathway;   negative regulation of GPCR protein signaling pathway;   negative regulation of GPCR protein signalling pathway
 narrow_synonym: inhibition of G-protein coupled receptor protein signaling pathway



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negative regulation of G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl5 C-C motif chemokine ligand 5 involved_in ISO (PMID:10734056) RGD PMID:10734056 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Cry1 cryptochrome circadian regulator 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5567906|PMID:20852621)
UniProt
RGD
PMID:20852621 GO_REF:0000024 MGI:5567906 NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 IDA RGD PMID:1403099 RGD:632163 NCBI chr 1:201,581,480...201,601,580
Ensembl chr 1:201,581,480...201,601,582
JBrowse link
G Grk3 G protein-coupled receptor kinase 3 IC RGD PMID:1403099 RGD:632163 NCBI chr12:43,624,778...43,735,375
Ensembl chr12:43,624,897...43,731,262
JBrowse link
G Klk14 kallikrein related-peptidase 14 involved_in ISO (PMID:16885167) RGD PMID:16885167 NCBI chr 1:94,123,131...94,137,239
Ensembl chr 1:94,131,998...94,137,240
JBrowse link
G Mgrn1 mahogunin ring finger 1 involved_in ISS
ISO
IBA
GO_REF:0000024
(PMID:19737927)
PMID:21873635
UniProt
RGD
PMID:19737927 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr10:10,638,881...10,688,332
Ensembl chr10:10,638,880...10,688,315
JBrowse link
G Plek pleckstrin involved_in ISO (PMID:7782310) RGD PMID:7782310 NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131
JBrowse link
G Rgs12 regulator of G-protein signaling 12 IEP RGD PMID:9651375 RGD:69959 NCBI chr14:75,715,925...75,824,012
Ensembl chr14:75,715,934...75,794,596
JBrowse link
G Rgs13 regulator of G-protein signaling 13 acts_upstream_of_or_within ISO (MGI:2385407|PMID:12193720) RGD PMID:12193720 MGI:2385407 NCBI chr13:55,922,290...55,955,753
Ensembl chr13:55,922,395...55,955,648
JBrowse link
G Rgs14 regulator of G-protein signaling 14 involved_in ISS
ISO
GO_REF:0000024
(MGI:5009199|PMID:10926822)
UniProt
RGD
PMID:10926822 GO_REF:0000024 MGI:5009199 NCBI chr17:9,248,982...9,263,104
Ensembl chr17:9,249,019...9,263,104
JBrowse link
G Rgs2 regulator of G-protein signaling 2 involved_in IEP
ISO
IMP
(MGI:3836877|PMID:19127022) RGD PMID:19127022 PMID:11968023 PMID:21798518 MGI:3836877, RGD:633858, RGD:7207364 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
JBrowse link
G Rgs4 regulator of G-protein signaling 4 IMP RGD PMID:21798518 PMID:9918533 RGD:7207364, RGD:7207376 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068
JBrowse link
G Rnf157 ring finger protein 157 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:101,571,972...101,639,874
Ensembl chr10:101,566,295...101,639,942
JBrowse link
G Rpgrip1l Rpgrip1-like involved_in ISO (PMID:19464661) RGD PMID:19464661 NCBI chr19:15,692,189...15,785,083
Ensembl chr19:15,692,150...15,785,083
JBrowse link
G Rph3al rabphilin 3A-like (without C2 domains) acts_upstream_of_or_within ISO MGI:3051976 (MGI:3044444|PMID:15159548) RGD PMID:15159548 MGI:3044444 NCBI chr10:60,689,943...60,833,354
Ensembl chr10:60,690,031...60,801,883
JBrowse link
G Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta involved_in ISO
ISS
(PMID:21224381)
GO_REF:0000024
RGD
UniProt
PMID:21224381 GO_REF:0000024 NCBI chr 3:152,659,663...152,682,105
Ensembl chr 3:152,659,651...152,682,105
JBrowse link
desensitization of G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gipr gastric inhibitory polypeptide receptor IDA RGD PMID:8928774 RGD:2312614 NCBI chr 1:78,804,287...78,814,462
Ensembl chr 1:78,805,593...78,814,462
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 involved_in
acts_upstream_of_or_within
IC
IBA
IEA
ISO
IDA
IMP
PMID:21873635
GO_REF:0000107
(PMID:15102938)
MGI:2180127|MGI:87937 (MGI:1337704|PMID:10338466), (MGI:84440|PMID:7761854)
PMID:18223549
Ensembl
RGD
PMID:7761854 PMID:10338466 PMID:15102938 PMID:1403099 PMID:21873635 More... GO_REF:0000107 MGI:1337704 MGI:84440, RGD:632163, RGD:13792537, RGD:8553863, RGD:13792694, RGD:7242040 NCBI chr 1:201,581,480...201,601,580
Ensembl chr 1:201,581,480...201,601,582
JBrowse link
G Grk3 G protein-coupled receptor kinase 3 involved_in IC
IBA
IMP
IDA
PMID:21873635 RGD
GO_Central
PMID:1403099 PMID:21873635 PMID:8381966 PMID:20837135 RGD:632163, RGD:13792537, RGD:5685621, RGD:5685022 NCBI chr12:43,624,778...43,735,375
Ensembl chr12:43,624,897...43,731,262
JBrowse link
G Grk4 G protein-coupled receptor kinase 4 IMP RGD PMID:15166006 RGD:1598508 NCBI chr14:75,998,554...76,080,808
Ensembl chr14:76,006,218...76,080,693
JBrowse link
G Grk5 G protein-coupled receptor kinase 5 IMP RGD PMID:8626574 PMID:30075183 RGD:61618, RGD:13792694 NCBI chr 1:260,028,269...260,223,699
Ensembl chr 1:260,028,242...260,218,701
JBrowse link
G Grk6 G protein-coupled receptor kinase 6 IDA
IMP
RGD PMID:12810562 PMID:17908240 RGD:1299124, RGD:7242040 NCBI chr17:9,177,018...9,192,644
Ensembl chr17:9,177,019...9,192,644
JBrowse link
G Grm5 glutamate metabotropic receptor 5 involved_in IDA PMID:12514208 UniProt PMID:12514208 RGD:728711 NCBI chr 1:141,310,069...141,884,980
Ensembl chr 1:141,312,368...141,882,274
JBrowse link
G Ly6g6e lymphocyte antigen 6 family member G6E acts_upstream_of_or_within ISO (MGI:5694852|PMID:26276394) RGD PMID:26276394 MGI:5694852 NCBI chr20:3,744,999...3,749,867
Ensembl chr20:3,744,999...3,750,849
JBrowse link
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:9350980 RGD:9850278 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434
JBrowse link
desensitization of G protein-coupled receptor signaling pathway by arrestin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenoceptor beta 2 involved_in ISO (PMID:15123695) RGD PMID:15123695 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Adrb3 adrenoceptor beta 3 NOT|involved_in ISO (PMID:15123695) RGD PMID:15123695 NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552
JBrowse link
G Arrb2 arrestin, beta 2 involved_in IMP
ISO
(PMID:12582207) RGD PMID:12582207 PMID:20705669 RGD:5509896 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link
G protein-coupled receptor catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Becn2 beclin 2 involved_in
acts_upstream_of_or_within
ISO (PMID:23954414)
UniProtKB:Q5JY77 (PMID:23954414)
MGI:5550535 (MGI:5528919|PMID:23954414)
RGD PMID:23954414 MGI:5528919 NCBI chr13:87,843,528...87,892,343
Ensembl chr13:87,844,531...87,845,787
JBrowse link
G Gprasp1 G protein-coupled receptor associated sorting protein 1 involved_in
acts_upstream_of_or_within
ISS
ISO
IEA
GO_REF:0000024
UniProtKB:A8MW95 (PMID:23954414)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:23954414 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:98,765,581...98,772,685
Ensembl chr  X:98,709,841...98,772,851
JBrowse link
G protein-coupled receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin involved_in ISO (PMID:10882736) RGD PMID:10882736 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Arr3 arrestin 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:65,699,881...65,712,224
Ensembl chr  X:65,698,699...65,712,153
JBrowse link
G Arrb1 arrestin, beta 1 involved_in IBA
ISO
PMID:21873635
(PMID:10521508), (PMID:12582207)
RGD PMID:10521508 PMID:12582207 PMID:21873635 RGD:13792537 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061
JBrowse link
G Arrb2 arrestin, beta 2 involved_in IBA
ISO
PMID:21873635
(PMID:10644702), (PMID:12582207)
RGD PMID:10644702 PMID:12582207 PMID:21873635 RGD:13792537 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link
G Calca calcitonin-related polypeptide alpha involved_in ISO (PMID:10882736) RGD PMID:10882736 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Dnm1 dynamin 1 IMP RGD PMID:14709338 RGD:9685157 NCBI chr 3:15,604,782...15,648,654
Ensembl chr 3:15,604,784...15,648,538
JBrowse link
G Dnm2 dynamin 2 IMP RGD PMID:14709338 RGD:9685157 NCBI chr 8:19,978,313...20,060,162
Ensembl chr 8:19,978,400...20,060,157
JBrowse link
G Drd2 dopamine receptor D2 IDA RGD PMID:14617818 RGD:1581465 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Drd3 dopamine receptor D3 involved_in IDA
ISO
(PMID:18424554) RGD PMID:18424554 PMID:14617818 RGD:1581465 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
JBrowse link
G Grk4 G protein-coupled receptor kinase 4 IMP RGD PMID:12519791 RGD:1304268 NCBI chr14:75,998,554...76,080,808
Ensembl chr14:76,006,218...76,080,693
JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B involved_in ISO (MGI:4821070|PMID:17325130) RGD PMID:17325130 MGI:4821070 NCBI chr 8:82,513,572...82,534,892
Ensembl chr 8:82,517,360...82,534,549
JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B involved_in IEA
ISO
GO_REF:0000107
(MGI:4821070|PMID:17325130)
Ensembl
RGD
PMID:17325130 GO_REF:0000107 MGI:4821070 NCBI chr 9:86,735,793...86,756,640
Ensembl chr 9:86,742,102...86,755,108
JBrowse link
G Pld2 phospholipase D2 acts_upstream_of_or_within ISO (MGI:3042801|PMID:14718562) RGD PMID:14718562 MGI:3042801 NCBI chr10:55,256,326...55,274,192
Ensembl chr10:55,256,359...55,272,808
JBrowse link
G Sag S-antigen visual arrestin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:88,467,797...88,508,821
Ensembl chr 9:88,469,376...88,508,820
JBrowse link
inhibitory G protein-coupled receptor phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk2b calcium/calmodulin-dependent protein kinase II beta acts_upstream_of_or_within ISO (MGI:4352609|PMID:19332541) RGD PMID:19332541 MGI:4352609 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994
JBrowse link
negative regulation of adenosine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase involved_in ISO
IBA
(PMID:16670267)
PMID:21873635
RGD PMID:16670267 PMID:21873635 RGD:13792537 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088
JBrowse link
negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrdc3 arrestin domain containing 3 acts_upstream_of_or_within ISO MGI:3877613 (MGI:5302794|PMID:21982743) RGD PMID:21982743 MGI:5302794 NCBI chr 2:11,137,443...11,149,978
Ensembl chr 2:11,137,460...11,149,978
JBrowse link
G Crtc3 CREB regulated transcription coactivator 3 acts_upstream_of_or_within ISO (MGI:4867567|PMID:21164481) RGD PMID:21164481 MGI:4867567 NCBI chr 1:134,552,830...134,655,929
Ensembl chr 1:134,554,696...134,655,500
JBrowse link
negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 involved_in ISO (PMID:17242280) RGD PMID:17242280 NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246
JBrowse link
G Gnai2 G protein subunit alpha i2 IDA RGD PMID:12631586 RGD:13508593 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979
JBrowse link
G Pde4b phosphodiesterase 4B involved_in ISO (MGI:5286798|PMID:21670503) RGD PMID:21670503 MGI:5286798 NCBI chr 5:116,799,827...117,367,707
Ensembl chr 5:116,799,971...117,367,696
JBrowse link
negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aplp1 amyloid beta precursor like protein 1 involved_in ISO (PMID:16531006) RGD PMID:16531006 NCBI chr 1:85,696,880...85,707,215
Ensembl chr 1:85,696,882...85,707,155
JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 acts_upstream_of_or_within ISO (MGI:3850921|PMID:19246489) RGD PMID:19246489 MGI:3850921 NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 IMP RGD PMID:30075183 RGD:13792694 NCBI chr 1:201,581,480...201,601,580
Ensembl chr 1:201,581,480...201,601,582
JBrowse link
G Grk5 G protein-coupled receptor kinase 5 IMP RGD PMID:30075183 RGD:13792694 NCBI chr 1:260,028,269...260,223,699
Ensembl chr 1:260,028,242...260,218,701
JBrowse link
G Mrap melanocortin 2 receptor accessory protein involved_in ISO (PMID:19329486) RGD PMID:19329486 NCBI chr11:29,991,974...30,003,024
Ensembl chr11:29,992,034...30,003,024
JBrowse link
G Mrap2 melanocortin 2 receptor accessory protein 2 involved_in ISO (PMID:19329486) RGD PMID:19329486 NCBI chr 8:88,088,293...88,144,636
Ensembl chr 8:88,088,272...88,143,886
JBrowse link
G Oprl1 opioid related nociceptin receptor 1 IDA RGD PMID:15748148 RGD:9835006 NCBI chr 3:168,831,934...168,839,920
Ensembl chr 3:168,834,003...168,839,920
JBrowse link
G Oprm1 opioid receptor, mu 1 IDA RGD PMID:15748148 RGD:9835006 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
JBrowse link
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:9013884 RGD:9850263 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434
JBrowse link
G Sstr4 somatostatin receptor 4 IDA RGD PMID:8175684 RGD:2325010 NCBI chr 3:135,854,826...135,856,689
Ensembl chr 3:135,854,826...135,856,689
JBrowse link
negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rgs2 regulator of G-protein signaling 2 involved_in ISO (MGI:5009116|PMID:21291891) RGD PMID:21291891 MGI:5009116 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
JBrowse link
negative regulation of G protein-coupled receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Necab2 N-terminal EF-hand calcium binding protein 2 involved_in ISO
IEA
(PMID:17689978)
GO_REF:0000107
RGD
Ensembl
PMID:17689978 GO_REF:0000107 NCBI chr19:47,501,351...47,527,722
Ensembl chr19:47,501,302...47,527,684
JBrowse link
G Ubqln2 ubiquilin 2 involved_in ISO (PMID:18199683) RGD PMID:18199683 NCBI chr  X:17,853,086...17,856,505
Ensembl chr  X:17,853,114...17,856,505
JBrowse link
negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bicd1 BICD cargo adaptor 1 involved_in IMP
ISO
PMID:20164183
(MGI:4887309|PMID:20164183)
RGD PMID:20164183 PMID:20164183 MGI:4887309, RGD:8693367 NCBI chr 4:182,479,071...182,631,504
Ensembl chr 4:182,479,071...182,627,434
JBrowse link
negative regulation of thrombin-activated receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Met MET proto-oncogene, receptor tyrosine kinase involved_in ISO
IEA
(PMID:25198505)
GO_REF:0000107
RGD
Ensembl
PMID:25198505 GO_REF:0000107 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
JBrowse link
G Snca synuclein alpha involved_in ISO (PMID:12239163) RGD PMID:12239163 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Stmn1 stathmin 1 involved_in ISO (PMID:25198505) RGD PMID:25198505 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
JBrowse link
positive regulation of G protein-coupled receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apela apelin receptor early endogenous ligand involved_in ISO (PMID:25639753) RGD PMID:25639753 NCBI chr16:24,694,231...24,703,466
Ensembl chr16:24,694,324...24,703,465
JBrowse link
G Apln apelin involved_in ISO
IDA
(PMID:11359874)
(MGI:5902690|PMID:11359874)
RGD PMID:11359874 PMID:11359874 MGI:5902690, RGD:12907555 NCBI chr  X:127,180,801...127,213,567
Ensembl chr  X:127,203,823...127,213,391
JBrowse link
G App amyloid beta precursor protein involved_in ISO (PMID:18723082) RGD PMID:18723082 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
positive regulation of inhibitory G protein-coupled receptor phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aplnr apelin receptor involved_in ISS
ISO
GO_REF:0000024
(PMID:25639753)
UniProt
RGD
PMID:25639753 GO_REF:0000024 NCBI chr 3:70,217,407...70,221,052
Ensembl chr 3:70,217,385...70,221,050
JBrowse link
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:15937517 RGD:10043344 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434
JBrowse link
prostaglandin receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:15937517 RGD:10043344 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434
JBrowse link
termination of G protein-coupled receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rgs12 regulator of G-protein signaling 12 IDA RGD PMID:11130074 RGD:7207399 NCBI chr14:75,715,925...75,824,012
Ensembl chr14:75,715,934...75,794,596
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18734
    cellular process 17431
      signal transduction 6808
        G protein-coupled receptor signaling pathway 2217
          negative regulation of G protein-coupled receptor signaling pathway 64
            G protein-coupled receptor catabolic process 2
            desensitization of G protein-coupled receptor signaling pathway + 31
            negative regulation of adenosine receptor signaling pathway 1
            negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway + 15
            negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process 1
            negative regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway 0
            negative regulation of angiotensin-activated signaling pathway 0
            negative regulation of beta1-adrenergic receptor activity 0
            negative regulation of octopamine or tyramine signaling pathway + 0
            negative regulation of opioid receptor signaling pathway + 0
            negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway + 1
            negative regulation of proteinase activated receptor activity 0
            negative regulation of thrombin-activated receptor signaling pathway 3
            suppression by symbiont of host G protein-coupled receptor signal transduction 0
            termination of G protein-coupled receptor signaling pathway 1
Path 2
Term Annotations click to browse term
  biological_process 18734
    biological regulation 13314
      regulation of biological process 12594
        regulation of cellular process 11909
          regulation of cell communication 3602
            negative regulation of cell communication 1500
              negative regulation of signal transduction 1351
                negative regulation of G protein-coupled receptor signaling pathway 64
                  G protein-coupled receptor catabolic process 2
                  desensitization of G protein-coupled receptor signaling pathway + 31
                  negative regulation of adenosine receptor signaling pathway 1
                  negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway + 15
                  negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process 1
                  negative regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway 0
                  negative regulation of angiotensin-activated signaling pathway 0
                  negative regulation of beta1-adrenergic receptor activity 0
                  negative regulation of octopamine or tyramine signaling pathway + 0
                  negative regulation of opioid receptor signaling pathway + 0
                  negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway + 1
                  negative regulation of proteinase activated receptor activity 0
                  negative regulation of thrombin-activated receptor signaling pathway 3
                  suppression by symbiont of host G protein-coupled receptor signal transduction 0
                  termination of G protein-coupled receptor signaling pathway 1
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