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ONTOLOGY REPORT - ANNOTATIONS


Term:G protein-coupled purinergic receptor signaling pathway
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Accession:GO:0035588 term browser browse the term
Definition:The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine or purine derivative and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.
Synonyms:exact_synonym: G-protein coupled purinergic receptor signalling pathway


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G protein-coupled adenosine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy5 adenylate cyclase 5 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:99402 (MGI:2387279|PMID:12223546)
Ensembl
RGD
PMID:12223546 GO_REF:0000107 MGI:2387279 NCBI chr11:68,695,839...68,842,452
Ensembl chr11:68,695,839...68,842,320
JBrowse link
G Adora1 adenosine A1 receptor involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Adora2a adenosine A2a receptor acts_upstream_of_or_within IDA
ISO
MGI:2155985|MGI:99673 (MGI:1860411|PMID:10845921), (MGI:2387279|PMID:12223546) RGD PMID:10845921 PMID:12223546, PMID:12590138 MGI:1860411 MGI:2387279, RGD:1625697 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
JBrowse link
G Adora2b adenosine A2B receptor involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:48,569,563...48,586,366
Ensembl chr10:48,569,555...48,586,365
JBrowse link
G Adora3 adenosine A3 receptor involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000002
(MGI:2664591|PMID:12817016)
InterPro
RGD
PMID:12817016 GO_REF:0000002 MGI:2664591 NCBI chr 2:208,336,909...208,379,217
Ensembl chr 2:208,373,154...208,376,803
JBrowse link
G Gnai2 G protein subunit alpha i2 involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:11923410, PMID:21873635 RGD:625670, RGD:13792537 NCBI chr 8:116,370,730...116,391,337
Ensembl chr 8:116,370,744...116,391,307
JBrowse link
G Gnat1 G protein subunit alpha transducin 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:116,433,302...116,438,038
Ensembl chr 8:116,433,302...116,438,038
JBrowse link
G LOC100911796 adenosine receptor A3-like involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:208,492,231...208,536,910
Ensembl chr 2:208,530,864...208,534,506
Ensembl chr 2:208,530,864...208,534,506
JBrowse link
G P2ry1 purinergic receptor P2Y1 involved_in IDA PMID:20847060 BHF-UCL PMID:20847060 RGD:8554370 NCBI chr 2:151,314,818...151,320,312
Ensembl chr 2:151,314,818...151,320,319
JBrowse link
G P2ry12 purinergic receptor P2Y12 IMP RGD PMID:12814667 RGD:6482299 NCBI chr 2:149,440,807...149,482,592
Ensembl chr 2:149,441,598...149,444,548
JBrowse link
negative regulation of adenosine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase involved_in IBA
ISO
PMID:21873635
(PMID:16670267)
RGD PMID:16670267, PMID:21873635 RGD:13792537 NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947
JBrowse link
positive regulation of adenosine receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp3 acid phosphatase 3 involved_in ISO
IEA
(PMID:18940592), (PMID:22389722)
GO_REF:0000107
RGD
Ensembl
PMID:18940592 PMID:22389722 GO_REF:0000107 NCBI chr 8:112,838,574...112,884,062
Ensembl chr 8:112,834,707...112,884,077
JBrowse link
G Cntn2 contactin 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2181052 (MGI:1930847|PMID:11178983)
Ensembl
RGD
PMID:11178983 GO_REF:0000107 MGI:1930847 NCBI chr13:49,280,913...49,314,061
Ensembl chr13:49,285,310...49,313,940
JBrowse link
G Necab2 N-terminal EF-hand calcium binding protein 2 involved_in ISO (PMID:17689978) RGD PMID:17689978 NCBI chr19:52,086,325...52,112,633
Ensembl chr19:52,086,325...52,112,629
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    signaling 7458
      signal transduction 6881
        G protein-coupled receptor signaling pathway 2331
          G protein-coupled purinergic receptor signaling pathway 14
            G protein-coupled adenosine receptor signaling pathway + 14
Path 2
Term Annotations click to browse term
  biological_process 19491
    biological regulation 13515
      regulation of biological process 12773
        regulation of cellular process 12275
          signal transduction 6881
            cell surface receptor signaling pathway 2774
              purinergic nucleotide receptor signaling pathway 33
                G protein-coupled purinergic receptor signaling pathway 14
                  G protein-coupled adenosine receptor signaling pathway + 14
paths to the root