RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: West Nile encephalitis
Accession: DOID:2365
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Definition: A viral infectious disease that results in inflammation located in brain, has_material_basis_in West Nile virus (Orthoflavivirus nilense), which is transmitted_by Culex, Aedes, or Anopheles species of mosquitoes. The infection has_symptom high fever, has_symptom headache, has_symptom neck stiffness, has_symptom stupor, has_symptom disorientation, has_symptom coma, has_symptom tremors, has_symptom convulsions, has_symptom muscle weakness, has_symptom vision loss, has_symptom numbness, and has_symptom paralysis. (DO)
Synonyms: exact_synonym: West Nile fever encephalitis; West Nile fever with encephalitis
xref: EFO:0007545 ; GARD:9959 ; ICD10CM:A92.31 ; ICD9CM:066.41
For additional species annotation, visit the
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Please select species to view GViewer data.
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
N
Ifih1
interferon induced with helicase C domain 1
ISO
mRNA:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chrNW_004624732:3,187,791...3,248,795
Ensembl chrNW_004624732:3,187,791...3,250,981
G
G
IFIH1
interferon induced with helicase C domain 1
ISO
mRNA:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chr10:47,676,799...47,732,310
Ensembl chr10:47,676,920...47,732,264
G
P
IFIH1
interferon induced with helicase C domain 1
ISO
mRNA:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chr15:68,930,998...68,985,145
Ensembl chr15:68,928,254...68,985,083
G
S
Ifih1
interferon induced with helicase C domain 1
ISO
mRNA:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chrNW_004936469:16,721,306...16,778,249
Ensembl chrNW_004936469:16,721,677...16,774,903
G
D
IFIH1
interferon induced with helicase C domain 1
ISO
mRNA:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chr36:7,668,925...7,727,040
Ensembl chr36:7,649,727...8,261,048
G
B
IFIH1
interferon induced with helicase C domain 1
ISO
mRNA:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chr2B:49,560,620...49,612,086
Ensembl chr2B:166,928,994...166,980,170
G
C
Ifih1
interferon induced with helicase C domain 1
ISO
mRNA:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chrNW_004955449:11,538,869...11,596,502
Ensembl chrNW_004955449:11,538,889...11,593,349
G
R
Ifih1
interferon induced with helicase C domain 1
ISO
mRNA:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chr 3:67,635,924...67,683,968
Ensembl chr 3:47,227,364...47,275,456
G
M
Ifih1
interferon induced with helicase C domain 1
IEP
mRNA:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chr 2:62,426,137...62,476,599
Ensembl chr 2:62,426,142...62,476,599
G
H
IFIH1
interferon induced with helicase C domain 1
ISO
mRNA:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chr 2:162,267,074...162,318,684
Ensembl chr 2:162,267,074...162,318,684
G
G
LCN2
lipocalin 2
ISO
mRNA,protein:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chr12:9,976,278...9,981,087
Ensembl chr12:9,976,614...9,980,870
G
P
LCN2
lipocalin 2
ISO
mRNA,protein:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chr 1:268,609,975...268,614,651
Ensembl chr 1:268,609,887...268,614,644
G
S
Lcn2
lipocalin 2
ISO
mRNA,protein:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chrNW_004936487:15,721,752...15,725,396
Ensembl chrNW_004936487:15,721,684...15,728,221
G
D
LCN2
lipocalin 2
ISO
mRNA,protein:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chr 9:55,328,118...55,342,535
Ensembl chr 9:55,328,133...55,332,038
G
B
LCN2
lipocalin 2
ISO
mRNA,protein:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chr 9:99,259,278...99,274,494
Ensembl chr 9:127,940,799...127,944,798
G
R
Lcn2
lipocalin 2
ISO
mRNA,protein:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:15,680,687...15,684,095
G
M
Lcn2
lipocalin 2
IEP
mRNA,protein:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264
G
H
LCN2
lipocalin 2
ISO
mRNA,protein:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453
G
R
Rig1
RNA sensor RIG-1
ISO
mRNA:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chr 5:60,117,398...60,165,995
Ensembl chr 5:55,321,235...55,370,819
G
N
Rigi
RNA sensor RIG-I
ISO
mRNA:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chrNW_004624736:37,134,718...37,204,543
Ensembl chrNW_004624736:37,133,059...37,197,218
G
G
RIGI
RNA sensor RIG-I
ISO
mRNA:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chr12:47,729,040...47,800,995
Ensembl chr12:47,729,076...47,799,570
G
P
RIGI
RNA sensor RIG-I
ISO
mRNA:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chr10:33,891,720...33,976,151
Ensembl chr10:33,891,763...33,933,455
G
S
Rigi
RNA sensor RIG-I
ISO
mRNA:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chrNW_004936524:1,141,840...1,200,638
Ensembl chrNW_004936524:1,140,971...1,200,638
G
D
RIGI
RNA sensor RIG-I
ISO
mRNA:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chr11:49,764,252...49,799,626
Ensembl chr11:49,764,267...49,799,527
G
B
RIGI
RNA sensor RIG-I
ISO
mRNA:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chr 9:32,230,012...32,302,159
Ensembl chr 9:33,040,000...33,110,557
G
C
Rigi
RNA sensor RIG-I
ISO
mRNA:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chrNW_004955472:3,093,895...3,135,524
Ensembl chrNW_004955472:3,093,939...3,133,987
G
M
Rigi
RNA sensor RIG-I
IEP
mRNA:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chr 4:40,203,775...40,239,843
Ensembl chr 4:40,203,773...40,239,828
G
H
RIGI
RNA sensor RIG-I
ISO
mRNA:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chr 9:32,455,302...32,526,196
Ensembl chr 9:32,455,302...32,526,348
G
N
Rnasel
ribonuclease L
disease_progression
ISO
RGD
PMID:16809306
RGD:40902815
NCBI chrNW_004624814:11,268,725...11,319,023
Ensembl chrNW_004624814:11,268,698...11,305,221
G
G
RNASEL
ribonuclease L
disease_progression
ISO
RGD
PMID:16809306
RGD:40902815
NCBI chr25:46,779,221...46,795,854
Ensembl chr25:46,779,700...46,795,842
G
P
RNASEL
ribonuclease L
disease_progression
ISO
RGD
PMID:16809306
RGD:40902815
NCBI chr 9:123,895,045...123,910,386
Ensembl chr 9:123,893,294...123,910,398
G
S
Rnasel
ribonuclease L
disease_progression
ISO
RGD
PMID:16809306
RGD:40902815
NCBI chrNW_004936481:7,165,400...7,177,342
Ensembl chrNW_004936481:7,165,353...7,177,538
G
D
RNASEL
ribonuclease L
disease_progression
ISO
RGD
PMID:16809306
RGD:40902815
NCBI chr 7:15,978,055...16,001,604
Ensembl chr 7:15,856,151...16,001,569
G
B
RNASEL
ribonuclease L
disease_progression
ISO
RGD
PMID:16809306
RGD:40902815
NCBI chr 1:158,092,346...158,108,026
Ensembl chr 1:161,741,645...161,760,045
G
C
Rnasel
ribonuclease L
disease_progression
ISO
RGD
PMID:16809306
RGD:40902815
NCBI chrNW_004955406:21,413,950...21,424,860
Ensembl chrNW_004955406:21,411,980...21,425,052
G
R
Rnasel
ribonuclease L
disease_progression
ISO
RGD
PMID:16809306
RGD:40902815
NCBI chr13:68,446,641...68,460,804
Ensembl chr13:65,901,459...65,908,704
G
M
Rnasel
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
disease_progression
IMP
RGD
PMID:16809306
RGD:40902815
NCBI chr 1:153,625,089...153,644,441
Ensembl chr 1:153,625,172...153,639,967
G
H
RNASEL
ribonuclease L
disease_progression
ISO
RGD
PMID:16809306
RGD:40902815
NCBI chr 1:182,573,634...182,589,256
Ensembl chr 1:182,573,634...182,589,256
G
N
Sting1
stimulator of interferon response cGAMP interactor 1
severity
ISO
RGD
PMID:31415679
RGD:39128224
NCBI chrNW_004624743:32,277,197...32,283,346
Ensembl chrNW_004624743:32,273,385...32,283,235
G
G
STING1
stimulator of interferon response cGAMP interactor 1
severity
ISO
RGD
PMID:31415679
RGD:39128224
NCBI chr23:42,153,576...42,160,903
Ensembl chr23:42,153,026...42,160,907
G
P
STING1
stimulator of interferon response cGAMP interactor 1
severity
ISO
RGD
PMID:31415679
RGD:39128224
NCBI chr 2:141,359,402...141,367,222
Ensembl chr 2:141,358,993...141,367,198
G
S
Sting1
stimulator of interferon response cGAMP interactor 1
severity
ISO
RGD
PMID:31415679
RGD:39128224
NCBI chrNW_004936531:8,555,966...8,562,829
Ensembl chrNW_004936531:8,555,637...8,562,885
G
D
STING1
stimulator of interferon response cGAMP interactor 1
severity
ISO
RGD
PMID:31415679
RGD:39128224
NCBI chr 2:34,783,947...34,792,204
Ensembl chr 2:34,784,232...34,789,072
G
B
STING1
stimulator of interferon response cGAMP interactor 1
severity
ISO
RGD
PMID:31415679
RGD:39128224
NCBI chr 5:134,845,689...134,852,938
Ensembl chr 5:140,967,399...140,973,846
G
C
Sting1
stimulator of interferon response cGAMP interactor 1
severity
ISO
RGD
PMID:31415679
RGD:39128224
NCBI chrNW_004955418:1,091,022...1,097,064
Ensembl chrNW_004955418:1,083,613...1,100,448
G
R
Sting1
stimulator of interferon response cGAMP interactor 1
severity
ISO
RGD
PMID:31415679
RGD:39128224
NCBI chr18:27,606,196...27,612,544
Ensembl chr18:27,332,119...27,338,335
G
M
Sting1
stimulator of interferon response cGAMP interactor 1
severity
IMP
RGD
PMID:31415679
RGD:39128224
NCBI chr18:35,866,731...35,873,607
Ensembl chr18:35,866,732...35,873,607
G
H
STING1
stimulator of interferon response cGAMP interactor 1
severity
ISO
RGD
PMID:31415679
RGD:39128224
NCBI chr 5:139,475,533...139,482,758
Ensembl chr 5:139,475,533...139,482,935
G
N
Tlr3
toll like receptor 3
ISO
mRNA:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chrNW_004624769:16,925,969...16,945,250
Ensembl chrNW_004624769:16,925,984...16,941,196
G
G
TLR3
toll like receptor 3
ISO
mRNA:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chr 7:131,991,068...132,014,366
Ensembl chr 7:131,991,029...132,016,232
G
P
TLR3
toll like receptor 3
ISO
mRNA:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chr15:46,966,262...46,977,774
Ensembl chr15:46,969,006...46,979,291
G
S
Tlr3
toll like receptor 3
ISO
mRNA:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chrNW_004936554:3,370,766...3,388,125
Ensembl chrNW_004936554:3,369,469...3,385,907
G
D
TLR3
toll like receptor 3
ISO
mRNA:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chr16:44,617,012...44,633,591
Ensembl chr16:44,550,846...44,653,247
G
B
TLR3
toll like receptor 3
ISO
mRNA:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chr 4:178,238,352...178,256,264
Ensembl chr 4:190,446,487...190,462,728
G
C
Tlr3
toll like receptor 3
ISO
mRNA:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chrNW_004955403:22,977,882...23,001,392
Ensembl chrNW_004955403:22,979,120...23,001,467
G
R
Tlr3
toll-like receptor 3
ISO
mRNA:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chr16:53,554,916...53,572,321
Ensembl chr16:46,822,039...46,836,545
G
M
Tlr3
toll-like receptor 3
IEP
mRNA:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chr 8:45,848,702...45,864,112
Ensembl chr 8:45,848,702...45,864,117
G
H
TLR3
toll like receptor 3
ISO
mRNA:increased expression:brain
RGD
PMID:24173226
RGD:126781836
NCBI chr 4:186,069,156...186,088,073
Ensembl chr 4:186,068,911...186,088,073
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