Ifih1 (interferon induced with helicase C domain 1) - Rat Genome Database

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Gene: Ifih1 (interferon induced with helicase C domain 1) Ictidomys tridecemlineatus
Analyze
Symbol: Ifih1
Name: interferon induced with helicase C domain 1
RGD ID: 12566312
Description: ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); DNA binding (inferred); INVOLVED IN antiviral innate immune response (ortholog); protein complex oligomerization (ortholog); type I interferon-mediated signaling pathway (ortholog); ASSOCIATED WITH Abnormal Reflexes (ortholog); Aicardi-Goutieres syndrome (ortholog); Aicardi-Goutieres Syndrome 7 (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: interferon-induced helicase C domain-containing protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303124,839,500 - 124,896,682 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646916,721,677 - 16,774,903 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646916,721,306 - 16,778,249 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA,ISO)
mitochondrion  (IEA)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ifih1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303124,839,500 - 124,896,682 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646916,721,677 - 16,774,903 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646916,721,306 - 16,778,249 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IFIH1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382162,267,074 - 162,318,684 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2162,267,074 - 162,318,684 (-)EnsemblGRCh38hg38GRCh38
GRCh372163,123,584 - 163,175,194 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362162,831,835 - 162,883,285 (-)NCBINCBI36Build 36hg18NCBI36
Build 342162,949,096 - 163,000,546NCBI
Celera2156,733,905 - 156,785,356 (-)NCBICelera
Cytogenetic Map2q24.2NCBI
HuRef2155,005,887 - 155,057,529 (-)NCBIHuRef
CHM1_12163,129,475 - 163,181,104 (-)NCBICHM1_1
T2T-CHM13v2.02162,723,727 - 162,775,351 (-)NCBIT2T-CHM13v2.0
Ifih1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39262,426,137 - 62,476,599 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl262,426,142 - 62,476,599 (-)EnsemblGRCm39 Ensembl
GRCm38262,595,618 - 62,646,255 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl262,595,798 - 62,646,255 (-)EnsemblGRCm38mm10GRCm38
MGSCv37262,433,850 - 62,484,312 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36262,398,289 - 62,451,864 (-)NCBIMGSCv36mm8
Celera264,286,036 - 64,336,570 (-)NCBICelera
Cytogenetic Map2C1.3NCBI
cM Map235.85NCBI
Ifih1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8367,635,924 - 67,683,968 (-)NCBIGRCr8
mRatBN7.2347,228,980 - 47,275,403 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl347,227,364 - 47,275,456 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx350,583,733 - 50,630,163 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0359,167,264 - 59,213,696 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0356,940,461 - 56,986,897 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0348,557,696 - 48,604,097 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl348,557,696 - 48,604,097 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0355,221,682 - 55,269,581 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4344,547,092 - 44,593,969 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera346,870,143 - 46,916,330 (-)NCBICelera
Cytogenetic Map3q21NCBI
Ifih1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544911,538,889 - 11,593,349 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544911,538,869 - 11,596,502 (+)NCBIChiLan1.0ChiLan1.0
IFIH1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21364,959,218 - 65,010,967 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B64,974,193 - 65,025,670 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B49,560,620 - 49,612,086 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B166,928,994 - 166,980,170 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B166,928,994 - 166,980,170 (-)Ensemblpanpan1.1panPan2
IFIH1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1367,668,925 - 7,727,040 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl367,649,727 - 8,261,048 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha367,812,658 - 7,870,597 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0367,800,592 - 7,858,795 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl367,799,925 - 7,859,590 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1367,819,125 - 7,877,043 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0367,860,049 - 7,918,195 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0367,967,525 - 8,025,700 (-)NCBIUU_Cfam_GSD_1.0
IFIH1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1568,928,254 - 68,985,083 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11568,930,998 - 68,985,145 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21576,422,958 - 76,477,124 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IFIH1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11047,676,799 - 47,732,310 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1047,676,920 - 47,732,264 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040151,800,300 - 151,852,344 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ifih1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247323,187,791 - 3,250,981 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247323,187,791 - 3,248,795 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000004981   ⟹   ENSSTOP00000004468
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493646916,721,677 - 16,774,903 (+)Ensembl
RefSeq Acc Id: XM_013355771   ⟹   XP_013211225
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303124,839,500 - 124,896,679 (-)NCBI
SpeTri2.0NW_00493646916,721,306 - 16,778,249 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040294388   ⟹   XP_040150322
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303124,842,817 - 124,896,681 (-)NCBI
RefSeq Acc Id: XM_040294389   ⟹   XP_040150323
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303124,842,817 - 124,896,681 (-)NCBI
RefSeq Acc Id: XM_040294390   ⟹   XP_040150324
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303124,842,817 - 124,896,682 (-)NCBI
RefSeq Acc Id: XM_040294391   ⟹   XP_040150325
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303124,842,817 - 124,896,043 (-)NCBI
Protein Sequences
Protein RefSeqs XP_013211225 (Get FASTA)   NCBI Sequence Viewer  
  XP_040150322 (Get FASTA)   NCBI Sequence Viewer  
  XP_040150323 (Get FASTA)   NCBI Sequence Viewer  
  XP_040150324 (Get FASTA)   NCBI Sequence Viewer  
  XP_040150325 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000004468.3
GenBank Protein KAG3274587 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_013211225   ⟸   XM_013355771
- Peptide Label: isoform X1
- UniProtKB: I3M585 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040150324   ⟸   XM_040294390
- Peptide Label: isoform X4
- UniProtKB: I3M585 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040150322   ⟸   XM_040294388
- Peptide Label: isoform X2
- UniProtKB: I3M585 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040150323   ⟸   XM_040294389
- Peptide Label: isoform X3
- UniProtKB: I3M585 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040150325   ⟸   XM_040294391
- Peptide Label: isoform X5
- UniProtKB: I3M585 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000004468   ⟸   ENSSTOT00000004981
Protein Domains
CARD   Helicase ATP-binding   Helicase C-terminal   RLR CTR


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000004953 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000004981.3 UniProtKB/TrEMBL
Gene3D-CATH 1.10.533.10 UniProtKB/TrEMBL
  1.20.1320.30 UniProtKB/TrEMBL
  2.170.150.30 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro CARD UniProtKB/TrEMBL
  CARD_dom UniProtKB/TrEMBL
  DEATH-like_dom_sf UniProtKB/TrEMBL
  Helicase/UvrB_N UniProtKB/TrEMBL
  Helicase_ATP-bd UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  RIG-I_C UniProtKB/TrEMBL
  RLR_C_sf UniProtKB/TrEMBL
  RLR_CTR UniProtKB/TrEMBL
NCBI Gene Ifih1 ENTREZGENE
PANTHER HELICASE WITH DEATH DOMAIN-RELATED UniProtKB/TrEMBL
  INTERFERON-INDUCED HELICASE C DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
Pfam CARD_2 UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  ResIII UniProtKB/TrEMBL
  RIG-I_C UniProtKB/TrEMBL
  RIG-I_C-RD UniProtKB/TrEMBL
PROSITE CARD UniProtKB/TrEMBL
  HELICASE_ATP_BIND_1 UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/TrEMBL
  RLR_CTR UniProtKB/TrEMBL
SMART DEXDc UniProtKB/TrEMBL
  HELICc UniProtKB/TrEMBL
Superfamily-SCOP SSF47986 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt I3M585 ENTREZGENE, UniProtKB/TrEMBL