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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:erythrosin(2-)
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Accession:CHEBI:87118 term browser browse the term
Definition:A benzoate obtained by deprotonation of the carboxy and phenol groups of erythrosin.
Synonyms:exact_synonym: 2-(2,4,5,7-tetraiodo-6-oxido-3-oxo-8a,10a-dihydro-3H-xanthen-9-yl)benzoate
 related_synonym: Formula=C20H8I4O5;   InChI=1S/C20H10I4O5/c21-11-5-9-13(7-3-1-2-4-8(7)20(27)28)10-6-12(22)17(26)15(24)19(10)29-18(9)14(23)16(11)25/h1-6,9,18,25H,(H,27,28)/p-2;   InChIKey=WTOSNONTQZJEBC-UHFFFAOYSA-L;   SMILES=[O-]C(=O)c1ccccc1C1=C2C=C(I)C(=O)C(I)=C2OC2C1C=C(I)C([O-])=C2I
 cyclic_relationship: is_conjugate_base_of CHEBI:87117


show annotations for term's descendants           Sort by:
erythrosin B term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A decreases activity ISO Erythrosine results in decreased activity of ABCB1 protein CTD PMID:20041016 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Casp9 caspase 9 multiple interactions EXP [Tartrazine co-treated with Erythrosine] affects the expression of CASP9 mRNA CTD PMID:32981412 Ensembl chr 5:154,109,046...154,126,626 JBrowse link
G Ccnd1 cyclin D1 increases expression ISO Erythrosine results in increased expression of CCND1 protein CTD PMID:8927716 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Cdk2 cyclin dependent kinase 2 increases activity ISO Erythrosine results in increased activity of CDK2 protein CTD PMID:8927716 PMID:9168006 NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity EXP Erythrosine results in decreased activity of CYP19A1 protein CTD PMID:18310892 NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity ISO Erythrosine results in decreased activity of CYP3A4 protein CTD PMID:20041016 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO Erythrosine results in increased expression of FOSL1 protein CTD PMID:20025956 NCBI chr 1:212,183,885...212,192,391
Ensembl chr 1:202,754,529...202,764,930 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Erythrosine inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions EXP [Tartrazine co-treated with Erythrosine] affects the expression of HAVCR1 mRNA CTD PMID:32981412 NCBI chr10:31,619,914...31,652,955
Ensembl chr10:31,119,088...31,151,698 		JBrowse link
G Hpgds hematopoietic prostaglandin D synthase decreases activity ISO Erythrosine results in decreased activity of HPGDS protein CTD PMID:25603235 NCBI chr 4:95,698,265...95,727,733
Ensembl chr 4:94,373,342...94,397,883 		JBrowse link
G Iyd iodotyrosine deiodinase decreases activity ISO Erythrosine results in decreased activity of IYD protein CTD PMID:24012475 NCBI chr 1:42,410,099...42,425,414
Ensembl chr 1:40,004,041...40,019,319 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO Erythrosine results in increased expression of JUN protein CTD PMID:20025956 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Orm1 orosomucoid 1 increases expression ISO Erythrosine results in increased expression of ORM1 protein CTD PMID:20025956 NCBI chr 5:81,788,509...81,791,661
Ensembl chr 5:76,772,941...76,776,154 		JBrowse link
G Phex phosphate regulating endopeptidase X-linked increases expression ISO Erythrosine results in increased expression of PHEX protein CTD PMID:20025956 NCBI chr  X:41,422,561...41,671,226
Ensembl chr  X:37,610,760...37,854,469 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP [Tartrazine co-treated with Erythrosine] results in increased expression of TNF mRNA CTD PMID:32981412 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tp53 tumor protein p53 increases activity ISO Erythrosine results in increased activity of TP53 protein CTD PMID:9168006 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Trh thyrotropin releasing hormone multiple interactions EXP Erythrosine promotes the reaction [TRH protein results in increased expression of TSHB protein] CTD PMID:2160137 NCBI chr 4:126,299,236...126,301,762
Ensembl chr 4:124,742,111...124,744,637 		JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions EXP Erythrosine promotes the reaction [TRH protein results in increased expression of TSHB protein] CTD PMID:2160137 NCBI chr 2:192,913,171...192,918,054
Ensembl chr 2:190,224,676...190,229,559 		JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 decreases activity ISO Erythrosine results in decreased activity of UGT1A6 protein CTD PMID:20041016 NCBI chr 9:96,195,018...96,256,264
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 decreases activity ISO Erythrosine results in decreased activity of UGT2B7 protein CTD PMID:20041016 NCBI chr14:21,251,535...21,274,451
Ensembl chr14:20,896,682...20,919,604 		JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO Erythrosine results in increased expression of VEGFA protein CTD PMID:20025956 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19879
    chemical entity 19877
      molecular entity 19876
        ion 17089
          anion 16654
            organic anion 6852
              phenolate anion 22
                erythrosin(2-) 21
                  erythrosin B 21
Path 2
Term Annotations click to browse term
  CHEBI ontology 19879
    subatomic particle 19877
      composite particle 19877
        hadron 19877
          baryon 19877
            nucleon 19877
              atomic nucleus 19877
                atom 19877
                  main group element atom 19816
                    p-block element atom 19816
                      carbon group element atom 19756
                        carbon atom 19753
                          organic molecular entity 19753
                            organic ion 11445
                              organic anion 6852
                                carboxylic acid anion 2496
                                  monocarboxylic acid anion 1605
                                    benzoates 1285
                                      erythrosin(2-) 21
                                        erythrosin B 21
paths to the root