|
G
|
Acaca
|
acetyl-CoA carboxylase alpha
|
decreases expression
|
EXP
|
Carnitine results in decreased expression of ACACA protein
|
CTD |
PMID:25669660 |
|
NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,014,170...69,276,457
|
|
G
|
Acacb
|
acetyl-CoA carboxylase beta
|
decreases expression
|
EXP
|
Carnitine results in decreased expression of ACACB protein
|
CTD |
PMID:25669660 |
|
NCBI chr12:48,026,394...48,138,214
Ensembl chr12:42,366,548...42,457,655
|
|
G
|
Adipoq
|
adiponectin, C1Q and collagen domain containing
|
increases expression
|
EXP
|
Carnitine results in increased expression of ADIPOQ protein
|
CTD |
PMID:30256492 |
|
NCBI chr11:91,226,524...91,240,244
Ensembl chr11:77,721,912...77,735,564
|
|
G
|
Akt1
|
AKT serine/threonine kinase 1
|
multiple interactions increases phosphorylation
|
EXP
|
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Carnitine results in increased phosphorylation of AKT1 protein]
|
CTD |
PMID:29186614 |
|
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921
|
|
G
|
App
|
amyloid beta precursor protein
|
multiple interactions
|
ISO
|
Carnitine promotes the reaction [Paraquat deficiency inhibits the reaction [Paraquat promotes the reaction [APP protein binds to APP protein]]]
|
CTD |
PMID:33290254 |
|
NCBI chr11:37,506,207...37,724,351
Ensembl chr11:24,019,778...24,236,561
|
|
G
|
Bax
|
BCL2 associated X, apoptosis regulator
|
decreases expression multiple interactions
|
EXP
|
Carnitine results in decreased expression of BAX protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Carnitine results in decreased expression of BAX protein]; Carnitine inhibits the reaction [Atrazine results in increased expression of BAX mRNA]; Carnitine inhibits the reaction [Methotrexate results in increased expression of BAX protein]
|
CTD |
PMID:29186614 PMID:36282381 PMID:37312617 |
|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368
|
|
G
|
Bbox1
|
gamma-butyrobetaine hydroxylase 1
|
multiple interactions increases chemical synthesis
|
ISO
|
Aluminum inhibits the reaction [BBOX1 protein results in increased chemical synthesis of Carnitine]; Hydrogen Peroxide inhibits the reaction [BBOX1 protein results in increased chemical synthesis of Carnitine]; Ketoglutaric Acids inhibits the reaction [Aluminum inhibits the reaction [BBOX1 protein results in increased chemical synthesis of Carnitine]]; Ketoglutaric Acids inhibits the reaction [Hydrogen Peroxide inhibits the reaction [BBOX1 protein results in increased chemical synthesis of Carnitine]]
|
CTD |
PMID:21439360 |
|
NCBI chr 3:96,822,654...96,871,786
Ensembl chr 3:96,822,655...96,871,458
|
|
G
|
Bcl2
|
BCL2, apoptosis regulator
|
multiple interactions increases phosphorylation
|
EXP
|
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Carnitine results in increased phosphorylation of BCL2 protein]; Carnitine inhibits the reaction [Atrazine results in decreased expression of BCL2 mRNA]; Carnitine inhibits the reaction [Ifosfamide results in decreased expression of BCL2 mRNA]; Carnitine inhibits the reaction [Methotrexate results in decreased expression of BCL2 protein]
|
CTD |
PMID:23213347 PMID:29186614 PMID:36282381 PMID:37312617 |
|
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
|
|
G
|
Bcl2l1
|
Bcl2-like 1
|
multiple interactions
|
EXP
|
Carnitine inhibits the reaction [Gentamicins results in decreased expression of BCL2L1 protein]
|
CTD |
PMID:19491382 |
|
NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:141,253,523...141,303,479 Ensembl chr 1:141,253,523...141,303,479
|
|
G
|
Casp3
|
caspase 3
|
multiple interactions increases expression
|
EXP ISO
|
Carnitine inhibits the reaction [Atrazine results in increased expression of CASP3 mRNA]; Carnitine inhibits the reaction [Gentamicins results in increased cleavage of CASP3 protein]; Carnitine inhibits the reaction [Ifosfamide results in increased expression of CASP3 mRNA]; Carnitine inhibits the reaction [Iohexol promotes the reaction [Glycerol results in increased expression of CASP3 mRNA]]; Carnitine inhibits the reaction [Methotrexate results in increased expression of CASP3 protein] Carnitine results in increased expression of CASP3 protein Carnitine inhibits the reaction [quinone results in increased activity of CASP3 protein]
|
CTD |
PMID:19491382 PMID:23213347 PMID:25669660 PMID:26562095 PMID:32478940 PMID:36282381 PMID:37312617 More...
|
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648
|
|
G
|
Casp8
|
caspase 8
|
multiple interactions
|
ISO
|
Carnitine inhibits the reaction [quinone results in increased activity of CASP8 protein]
|
CTD |
PMID:32478940 |
|
NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:60,264,075...60,312,542
|
|
G
|
Casp9
|
caspase 9
|
multiple interactions
|
EXP ISO
|
Carnitine inhibits the reaction [Ifosfamide results in increased expression of CASP9 mRNA] Carnitine inhibits the reaction [quinone results in increased activity of CASP9 protein]
|
CTD |
PMID:23213347 PMID:32478940 |
|
Ensembl chr 5:154,109,046...154,126,626
|
|
G
|
Cat
|
catalase
|
multiple interactions
|
EXP
|
Carnitine inhibits the reaction [Diethylnitrosamine results in decreased activity of CAT protein]; Carnitine inhibits the reaction [Doxorubicin results in decreased activity of CAT protein]; Carnitine inhibits the reaction [Ifosfamide results in decreased expression of CAT mRNA]
|
CTD |
PMID:16889571 PMID:19294768 PMID:23213347 |
|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478
|
|
G
|
Ccn2
|
cellular communication network factor 2
|
multiple interactions
|
EXP
|
Carnitine inhibits the reaction [Sunitinib results in increased expression of CCN2 mRNA]
|
CTD |
PMID:26581635 |
|
NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:20,802,199...20,805,734
|
|
G
|
Cdh1
|
cadherin 1
|
multiple interactions
|
EXP
|
Carnitine inhibits the reaction [perfluorooctane sulfonic acid results in decreased expression of CDH1 protein]
|
CTD |
PMID:28973641 |
|
NCBI chr19:51,402,178...51,471,572
Ensembl chr19:34,492,371...34,561,775
|
|
G
|
Col1a1
|
collagen type I alpha 1 chain
|
multiple interactions
|
EXP
|
Carnitine inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of COL1A1 mRNA]; Carnitine inhibits the reaction [Sunitinib results in increased expression of COL1A1 mRNA]
|
CTD |
PMID:26581635 PMID:28973641 |
|
NCBI chr10:80,380,458...80,397,461
Ensembl chr10:79,883,622...79,900,624
|
|
G
|
Col2a1
|
collagen type II alpha 1 chain
|
multiple interactions
|
EXP
|
[COL2A1 protein co-treated with Freund's Adjuvant] affects the abundance of Carnitine; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Carnitine]; Dexamethasone inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Carnitine]; huang-lien-chieh-tu-tang inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Carnitine]
|
CTD |
PMID:24709313 |
|
NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546
|
|
G
|
Cpt1a
|
carnitine palmitoyltransferase 1A
|
multiple interactions
|
EXP ISO
|
valproyl-coenzyme A inhibits the reaction [CPT1A protein results in increased metabolism of Carnitine] [Doxorubicin co-treated with Carnitine] results in increased expression of CPT1A mRNA; [Genistein co-treated with Carnitine] results in increased expression of CPT1A protein; Carnitine inhibits the reaction [quinone results in decreased expression of CPT1A protein]
|
CTD |
PMID:16283381 PMID:16362726 PMID:19854160 PMID:32478940 |
|
NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:200,565,613...200,627,055
|
|
G
|
Cpt2
|
carnitine palmitoyltransferase 2
|
multiple interactions increases expression
|
ISO EXP
|
Carnitine promotes the reaction [[Bezafibrate results in increased activity of CPT2 protein] which results in increased abundance of Adenosine Triphosphate] Carnitine results in increased expression of CPT2 protein
|
CTD |
PMID:21816645 PMID:25669660 |
|
NCBI chr 5:127,893,450...127,911,347
Ensembl chr 5:122,664,677...122,682,095
|
|
G
|
Cybb
|
cytochrome b-245 beta chain
|
multiple interactions
|
EXP
|
Carnitine inhibits the reaction [Sunitinib results in increased expression of CYBB mRNA]; Carnitine inhibits the reaction [Sunitinib results in increased expression of CYBB protein]
|
CTD |
PMID:26581635 |
|
NCBI chr X:16,030,596...16,065,065
Ensembl chr X:13,359,430...13,392,586
|
|
G
|
Cyp17a1
|
cytochrome P450, family 17, subfamily a, polypeptide 1
|
multiple interactions
|
EXP
|
Carnitine inhibits the reaction [Atrazine results in decreased expression of CYP17A1 mRNA]
|
CTD |
PMID:29710542 |
|
NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:245,535,462...245,541,573
|
|
G
|
Cyp2e1
|
cytochrome P450, family 2, subfamily e, polypeptide 1
|
multiple interactions
|
EXP
|
Carnitine promotes the reaction [Ethanol results in increased expression of CYP2E1 protein]
|
CTD |
PMID:8130774 |
|
NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:195,840,058...195,864,023
|
|
G
|
Fabp3
|
fatty acid binding protein 3
|
multiple interactions
|
EXP
|
Carnitine inhibits the reaction [Doxorubicin results in decreased expression of FABP3 mRNA]
|
CTD |
PMID:20470772 |
|
NCBI chr 5:147,936,027...147,942,870
Ensembl chr 5:142,651,956...142,658,718
|
|
G
|
Fabp9
|
fatty acid binding protein 9
|
multiple interactions
|
EXP
|
Carnitine inhibits the reaction [carbendazim results in decreased expression of FABP9 mRNA]; Carnitine inhibits the reaction [carbendazim results in decreased expression of FABP9 protein]
|
CTD |
PMID:33965443 |
|
NCBI chr 2:91,591,842...91,595,873
Ensembl chr 2:91,592,298...91,595,873
|
|
G
|
Fasn
|
fatty acid synthase
|
decreases expression
|
EXP
|
Carnitine results in decreased expression of FASN protein
|
CTD |
PMID:25669660 |
|
NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,072,091...106,090,261
|
|
G
|
Fshb
|
follicle stimulating hormone subunit beta
|
multiple interactions
|
EXP
|
Carnitine inhibits the reaction [carbendazim results in decreased expression of FSHB protein]
|
CTD |
PMID:33965443 |
|
NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:93,548,560...93,552,370
|
|
G
|
Gdf9
|
growth differentiation factor 9
|
multiple interactions increases expression
|
ISO
|
Carnitine inhibits the reaction [Cyclophosphamide results in decreased expression of GDF9 mRNA] Carnitine results in increased expression of GDF9 mRNA
|
CTD |
PMID:37863343 |
|
NCBI chr10:37,589,200...37,599,970
Ensembl chr10:37,595,679...37,599,672
|
|
G
|
Gfap
|
glial fibrillary acidic protein
|
multiple interactions
|
EXP
|
Carnitine inhibits the reaction [Atrazine results in increased expression of GFAP protein]
|
CTD |
PMID:36282381 |
|
NCBI chr10:88,352,987...88,361,661
Ensembl chr10:87,852,890...87,861,589
|
|
G
|
Gja1
|
gap junction protein, alpha 1
|
multiple interactions increases expression
|
ISO
|
Carnitine inhibits the reaction [Cyclophosphamide results in decreased expression of GJA1 mRNA] Carnitine results in increased expression of GJA1 mRNA
|
CTD |
PMID:37863343 |
|
NCBI chr20:36,302,490...36,315,010
Ensembl chr20:35,755,991...35,768,582
|
|
G
|
Gja4
|
gap junction protein, alpha 4
|
increases expression multiple interactions
|
ISO
|
Carnitine results in increased expression of GJA4 mRNA Carnitine inhibits the reaction [Cyclophosphamide results in decreased expression of GJA4 mRNA]
|
CTD |
PMID:37863343 |
|
NCBI chr 5:144,917,791...144,920,324
Ensembl chr 5:139,633,287...139,635,925
|
|
G
|
Gpt
|
glutamic--pyruvic transaminase
|
multiple interactions
|
EXP
|
Carnitine inhibits the reaction [Atrazine results in increased activity of GPT protein]
|
CTD |
PMID:36282381 |
|
NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:108,416,642...108,419,494
|
|
G
|
Gpx1
|
glutathione peroxidase 1
|
multiple interactions
|
EXP
|
Carnitine inhibits the reaction [Ifosfamide results in decreased expression of GPX1 mRNA]
|
CTD |
PMID:23213347 |
|
NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024
|
|
G
|
Hadha
|
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
|
multiple interactions
|
ISO
|
Carnitine inhibits the reaction [quinone results in decreased expression of HADHA protein]
|
CTD |
PMID:32478940 |
|
NCBI chr 6:31,907,801...31,947,434
Ensembl chr 6:26,187,956...26,227,869
|
|
G
|
Has2
|
hyaluronan synthase 2
|
multiple interactions increases expression
|
ISO
|
Carnitine inhibits the reaction [Cyclophosphamide results in decreased expression of HAS2 mRNA] Carnitine results in increased expression of HAS2 mRNA
|
CTD |
PMID:37863343 |
|
NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933
|
|
G
|
Hmox1
|
heme oxygenase 1
|
multiple interactions
|
EXP
|
Carnitine inhibits the reaction [Methotrexate results in decreased expression of HMOX1 protein]
|
CTD |
PMID:37312617 |
|
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079
|
|
G
|
Hrk
|
harakiri, BCL2 interacting protein
|
multiple interactions
|
ISO
|
Carnitine inhibits the reaction [Gentamicins results in increased expression of HRK mRNA]; Carnitine inhibits the reaction [Gentamicins results in increased expression of HRK protein]
|
CTD |
PMID:16239342 |
|
NCBI chr12:44,048,402...44,070,561
|
|
G
|
Hspa2
|
heat shock protein family A (Hsp70) member 2
|
multiple interactions
|
EXP
|
Carnitine inhibits the reaction [Cadmium Chloride results in increased expression of HSPA2 protein]
|
CTD |
PMID:22359436 |
|
NCBI chr 6:100,864,172...100,866,946
Ensembl chr 6:95,128,350...95,131,287
|
|
G
|
Idh2
|
isocitrate dehydrogenase (NADP(+)) 2
|
multiple interactions increases abundance
|
ISO
|
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Carnitine]
|
CTD |
PMID:27469509 |
|
NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:134,029,772...134,058,025
|
|
G
|
Il10
|
interleukin 10
|
multiple interactions
|
EXP
|
Carnitine inhibits the reaction [carbendazim results in decreased expression of IL10 protein]; Carnitine inhibits the reaction [Sunitinib results in decreased expression of IL10 mRNA]
|
CTD |
PMID:26581635 PMID:33965443 |
|
NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313
|
|
G
|
Il18
|
interleukin 18
|
increases expression
|
EXP
|
Carnitine results in increased expression of IL18 protein
|
CTD |
PMID:25669660 |
|
NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:50,906,960...50,932,887
|
|
G
|
Il1b
|
interleukin 1 beta
|
multiple interactions increases expression
|
EXP
|
Carnitine inhibits the reaction [Iohexol promotes the reaction [Glycerol results in increased expression of IL1B mRNA]]; Carnitine inhibits the reaction [sunitinib results in increased expression of IL1B mRNA] Carnitine results in increased expression of IL1B protein
|
CTD |
PMID:25669660 PMID:26562095 PMID:26581635 |
|
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415
|
|
G
|
Il6
|
interleukin 6
|
multiple interactions
|
EXP
|
Carnitine inhibits the reaction [carbendazim results in increased expression of IL6 protein]; Carnitine inhibits the reaction [Methotrexate results in increased expression of IL6 protein]; Carnitine inhibits the reaction [Sunitinib results in increased expression of IL6 mRNA]
|
CTD |
PMID:26581635 PMID:33965443 PMID:37312617 |
|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178
|
|
G
|
Ins1
|
insulin 1
|
decreases uptake multiple interactions
|
ISO EXP
|
INS1 protein results in decreased uptake of Carnitine Carnitine inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased secretion of INS1 protein]
|
CTD |
PMID:28298333 PMID:30256492 |
|
NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:251,244,973...251,245,536
|
|
G
|
Ldha
|
lactate dehydrogenase A
|
multiple interactions
|
ISO
|
Carnitine inhibits the reaction [Doxorubicin results in increased activity of LDHA protein]
|
CTD |
PMID:37453608 |
|
NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:97,366,021...97,433,472
|
|
G
|
Lepr
|
leptin receptor
|
affects abundance
|
ISO
|
LEPR affects the abundance of Carnitine
|
CTD |
PMID:20567778 |
|
NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:116,289,823...116,475,908
|
|
G
|
Lhb
|
luteinizing hormone subunit beta
|
multiple interactions
|
EXP
|
Carnitine inhibits the reaction [carbendazim results in decreased expression of LHB protein]
|
CTD |
PMID:33965443 |
|
NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
|
|
G
|
Mmp9
|
matrix metallopeptidase 9
|
multiple interactions
|
EXP
|
Carnitine inhibits the reaction [sunitinib results in decreased expression of MMP9 mRNA]
|
CTD |
PMID:26581635 |
|
NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120
|
|
G
|
Mpo
|
myeloperoxidase
|
multiple interactions increases activity
|
EXP
|
[Carboplatin co-treated with Carnitine deficiency] results in increased expression of MPO protein; Acetaminophen promotes the reaction [Carnitine deficiency results in increased activity of MPO protein]
|
CTD |
PMID:18597074 PMID:18852009 |
|
NCBI chr10:73,092,124...73,102,057
Ensembl chr10:72,594,661...72,604,819
|
|
G
|
Mt-co1
|
mitochondrially encoded cytochrome c oxidase I
|
multiple interactions
|
ISO
|
Carnitine inhibits the reaction [nickel chloride results in decreased expression of COX1 mRNA]
|
CTD |
PMID:21419151 |
|
NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
|
|
G
|
Mt-nd6
|
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6
|
multiple interactions
|
ISO
|
Carnitine inhibits the reaction [nickel chloride results in decreased expression of ND6 mRNA]
|
CTD |
PMID:21419151 |
|
NCBI chr MT:13,543...14,061
Ensembl chr MT:13,543...14,061
|
|
G
|
Mttp
|
microsomal triglyceride transfer protein
|
multiple interactions
|
EXP
|
Carnitine inhibits the reaction [Stavudine results in decreased expression of MTTP mRNA]
|
CTD |
PMID:18299183 |
|
NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
|
|
G
|
Nfe2l2
|
NFE2 like bZIP transcription factor 2
|
multiple interactions
|
EXP
|
Carnitine inhibits the reaction [Methotrexate results in decreased expression of NFE2L2 protein]
|
CTD |
PMID:37312617 |
|
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737
|
|
G
|
Nlrp3
|
NLR family, pyrin domain containing 3
|
increases expression
|
EXP
|
Carnitine results in increased expression of NLRP3 protein
|
CTD |
PMID:25669660 |
|
NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,328,566...44,352,811
|
|
G
|
Nos2
|
nitric oxide synthase 2
|
multiple interactions
|
EXP
|
Carnitine inhibits the reaction [carbendazim results in increased expression of NOS2 protein]; Carnitine inhibits the reaction [Ifosfamide results in increased expression of NOS2 mRNA]
|
CTD |
PMID:23213347 PMID:33965443 |
|
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:63,815,308...63,851,210
|
|
G
|
Nos3
|
nitric oxide synthase 3
|
increases expression
|
EXP
|
Carnitine results in increased expression of NOS3
|
CTD |
PMID:20123095 |
|
NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:10,793,834...10,814,166
|
|
G
|
Ocln
|
occludin
|
multiple interactions
|
EXP
|
Carnitine inhibits the reaction [carbendazim results in decreased expression of OCLN protein]
|
CTD |
PMID:33965443 |
|
NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:31,657,220...31,764,150
|
|
G
|
Ppara
|
peroxisome proliferator activated receptor alpha
|
multiple interactions increases expression increases activity
|
EXP
|
[pirinixic acid results in increased activity of PPARA protein] promotes the reaction [SLC22A21 protein results in increased uptake of Carnitine]; PPARA protein promotes the reaction [Carnitine results in decreased susceptibility to Gentamicins] Carnitine results in increased expression of PPARA protein Carnitine results in increased activity of PPARA protein
|
CTD |
PMID:19491382 PMID:19735737 PMID:25669660 |
|
NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346
|
|
G
|
Pparg
|
peroxisome proliferator-activated receptor gamma
|
increases expression multiple interactions
|
EXP
|
Carnitine results in increased expression of PPARG protein Carnitine inhibits the reaction [[Dietary Fats co-treated with Fructose] results in decreased expression of PPARG protein]
|
CTD |
PMID:30256492 |
|
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:148,423,194...148,548,468
|
|
G
|
Ppargc1a
|
PPARG coactivator 1 alpha
|
multiple interactions
|
EXP
|
Carnitine inhibits the reaction [Methotrexate results in decreased expression of PPARGC1A protein]
|
CTD |
PMID:37312617 |
|
NCBI chr14:63,073,505...63,729,215
Ensembl chr14:58,861,144...59,512,656
|
|
G
|
Ptgis
|
prostaglandin I2 synthase
|
increases expression increases response to substance multiple interactions
|
EXP
|
Carnitine results in increased expression of PTGIS mRNA PTGIS protein results in increased susceptibility to Carnitine [Carnitine results in increased expression of PTGIS mRNA] which results in increased chemical synthesis of 6-Ketoprostaglandin F1 alpha
|
CTD |
PMID:19491382 |
|
NCBI chr 3:176,347,589...176,383,251
Ensembl chr 3:155,916,412...155,965,451
|
|
G
|
Pycard
|
PYD and CARD domain containing
|
increases expression
|
EXP
|
Carnitine results in increased expression of PYCARD protein
|
CTD |
PMID:25669660 |
|
NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:182,601,174...182,602,955
|
|
G
|
Rela
|
RELA proto-oncogene, NF-kB subunit
|
multiple interactions
|
EXP
|
Carnitine inhibits the reaction [carbendazim results in increased expression of RELA protein]
|
CTD |
PMID:33965443 |
|
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484
|
|
G
|
Scd
|
stearoyl-CoA desaturase
|
decreases expression
|
EXP
|
Carnitine results in decreased expression of SCD protein
|
CTD |
PMID:25669660 |
|
NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:243,269,747...243,282,562
|
|
G
|
Sirt1
|
sirtuin 1
|
multiple interactions
|
EXP
|
Carnitine inhibits the reaction [Methotrexate results in decreased expression of SIRT1 protein]
|
CTD |
PMID:37312617 |
|
NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,306,917...25,329,260
|
|
G
|
Sirt3
|
sirtuin 3
|
multiple interactions
|
ISO
|
Carnitine inhibits the reaction [Cyclophosphamide results in increased expression of SIRT3 mRNA]
|
CTD |
PMID:37863343 |
|
NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808
|
|
G
|
Slc22a1
|
solute carrier family 22 member 1
|
decreases expression
|
EXP
|
Carnitine results in decreased expression of SLC22A1 protein
|
CTD |
PMID:25669660 |
|
NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
|
|
G
|
Slc22a2
|
solute carrier family 22 member 2
|
decreases expression
|
EXP
|
Carnitine results in decreased expression of SLC22A2 protein
|
CTD |
PMID:25669660 |
|
NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:48,121,061...48,163,268
|
|
G
|
Slc22a21
|
solute carrier family 22 (organic cation transporter), member 21
|
multiple interactions increases uptake
|
EXP
|
[pirinixic acid results in increased activity of PPARA protein] promotes the reaction [SLC22A21 protein results in increased uptake of Carnitine]
|
CTD |
PMID:19735737 |
|
NCBI chr10:38,104,114...38,133,106
Ensembl chr10:38,104,122...38,130,671
|
|
G
|
Slc22a4
|
solute carrier family 22 member 4
|
increases uptake decreases expression
|
ISO EXP
|
SLC22A4 protein results in increased uptake of Carnitine Carnitine results in decreased expression of SLC22A4 protein
|
CTD |
PMID:21256917 PMID:25669660 PMID:33007874 |
|
NCBI chr10:38,133,333...38,179,932
Ensembl chr10:38,133,322...38,179,720
|
|
G
|
Slc22a5
|
solute carrier family 22 member 5
|
multiple interactions affects expression decreases expression increases transport increases uptake increases expression affects uptake affects binding
|
ISO EXP
|
[Doxorubicin co-treated with Carnitine] results in increased expression of SLC22A5 mRNA; Amiodarone inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Atorvastatin inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Betaine inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Carnitine inhibits the reaction [SLC22A5 protein results in increased abundance of Doxorubicin]; Carnitine inhibits the reaction [SLC22A5 protein results in increased transport of pivaloylcarnitine]; Choline inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Clozapine inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; grepafloxacin affects the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Ipratropium inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Lidocaine inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Nifedipine inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Ofloxacin inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Olanzapine inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine analog]; pivaloylcarnitine inhibits the reaction [SLC22A5 protein results in increased transport of Carnitine]; Propranolol inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Quetiapine Fumarate inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Spironolactone inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; talinolol inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; ziprasidone inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine] Carnitine affects the expression of SLC22A5 protein Carnitine inhibits the reaction [SLC22A5 protein results in increased abundance of and results in increased localization of Doxorubicin] Carnitine results in decreased expression of SLC22A5 mRNA; Carnitine results in decreased expression of SLC22A5 protein 1-Methyl-4-phenylpyridinium inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Carnitine inhibits the reaction [Cyclophosphamide results in decreased expression of SLC22A5 mRNA]; Carnitine inhibits the reaction [Cyclophosphamide results in decreased expression of SLC22A5 protein]; Carnitine inhibits the reaction [Doxorubicin results in decreased expression of SLC22A5 mRNA]; Carnitine inhibits the reaction [SLC22A5 protein results in increased uptake of Tetraethylammonium]; Dithioerythritol inhibits the reaction [Omeprazole inhibits the reaction [SLC22A5 protein results in increased transport of Carnitine]]; Ofloxacin inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]; Omeprazole inhibits the reaction [SLC22A5 protein results in increased transport of Carnitine]; Tetraethylammonium inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine] Carnitine deficiency results in increased expression of SLC22A5 mRNA SLC22A5 protein results in increased uptake of Carnitine; SLC22A5 protein results in increased uptake of Carnitine analog SLC22A5 protein affects the uptake of Carnitine Carnitine binds to SLC22A5 protein
|
CTD |
PMID:12644265 PMID:15486076 PMID:16283381 PMID:16928358 PMID:18762717 PMID:18981167 PMID:19041296 PMID:19539806 PMID:19735737 PMID:20303936 PMID:20470772 PMID:21256917 PMID:21641380 PMID:22701146 PMID:25669660 PMID:30465787 PMID:31437515 PMID:33007874 PMID:37453608 More...
|
|
NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309
|
|
G
|
Slc22a8
|
solute carrier family 22 member 8
|
increases transport
|
ISO
|
SLC22A8 protein results in increased transport of Carnitine
|
CTD |
PMID:15100168 |
|
NCBI chr 1:214,925,506...214,945,516
Ensembl chr 1:205,498,084...205,517,450
|
|
G
|
Slc25a20
|
solute carrier family 25 member 20
|
multiple interactions increases transport
|
EXP
|
Ampicillin inhibits the reaction [SLC25A20 protein results in increased transport of Carnitine]; Carnitine inhibits the reaction [Hydrogen Peroxide results in decreased activity of SLC25A20 protein]; Cefazolin inhibits the reaction [SLC25A20 protein results in increased transport of Carnitine]; Cefonicid inhibits the reaction [SLC25A20 protein results in increased transport of Carnitine]; Cephalothin inhibits the reaction [SLC25A20 protein results in increased transport of Carnitine]; Piperacillin inhibits the reaction [SLC25A20 protein results in increased transport of Carnitine]
|
CTD |
PMID:18452908 PMID:23402788 |
|
NCBI chr 8:118,243,573...118,265,027
Ensembl chr 8:109,365,002...109,386,512
|
|
G
|
Slc2a4
|
solute carrier family 2 member 4
|
increases expression multiple interactions
|
EXP
|
Carnitine results in increased expression of SLC2A4 protein Carnitine inhibits the reaction [[Dietary Fats co-treated with Fructose] results in decreased expression of SLC2A4 protein]
|
CTD |
PMID:30256492 |
|
NCBI chr10:55,164,721...55,170,289
Ensembl chr10:54,666,015...54,671,565
|
|
G
|
Snai1
|
snail family transcriptional repressor 1
|
multiple interactions
|
EXP
|
Carnitine inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of SNAI1 protein]
|
CTD |
PMID:28973641 |
|
NCBI chr 3:176,667,476...176,671,965
Ensembl chr 3:156,248,485...156,252,969
|
|
G
|
Srebf1
|
sterol regulatory element binding transcription factor 1
|
multiple interactions decreases expression
|
EXP
|
Carnitine inhibits the reaction [Stavudine results in increased expression of SREBF1 mRNA] Carnitine results in decreased expression of SREBF1 protein
|
CTD |
PMID:18299183 PMID:25669660 |
|
NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,007,637...45,029,650
|
|
G
|
Star
|
steroidogenic acute regulatory protein
|
multiple interactions
|
EXP
|
Carnitine inhibits the reaction [carbendazim results in decreased expression of STAR mRNA]; Carnitine inhibits the reaction [carbendazim results in decreased expression of STAR protein]
|
CTD |
PMID:33965443 |
|
NCBI chr16:72,969,824...72,974,447
Ensembl chr16:66,264,807...66,271,672
|
|
G
|
Tgfb1
|
transforming growth factor, beta 1
|
multiple interactions
|
EXP
|
Carnitine inhibits the reaction [Iohexol promotes the reaction [Glycerol results in increased expression of TGFB1 mRNA]]; Carnitine inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of TGFB1 mRNA]; Carnitine inhibits the reaction [sunitinib results in increased expression of TGFB1 mRNA]
|
CTD |
PMID:26562095 PMID:26581635 PMID:28973641 |
|
NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847
|
|
G
|
Timp1
|
TIMP metallopeptidase inhibitor 1
|
multiple interactions
|
EXP
|
Carnitine inhibits the reaction [sunitinib results in increased expression of TIMP1 mRNA]
|
CTD |
PMID:26581635 |
|
NCBI chr X:3,766,509...3,772,578
Ensembl chr X:1,212,972...1,217,664
|
|
G
|
Tjp1
|
tight junction protein 1
|
multiple interactions
|
EXP
|
Carnitine inhibits the reaction [perfluorooctane sulfonic acid results in decreased expression of TJP1 protein]
|
CTD |
PMID:28973641 |
|
NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:118,849,838...119,094,432
|
|
G
|
Tnf
|
tumor necrosis factor
|
increases expression multiple interactions decreases expression
|
EXP
|
Carnitine deficiency results in increased expression of TNF mRNA [Carboplatin co-treated with Carnitine deficiency] results in increased expression of TNF protein; Acetaminophen promotes the reaction [Carnitine deficiency results in increased expression of TNF mRNA]; Carnitine inhibits the reaction [carbendazim results in increased expression of TNF protein]; Carnitine inhibits the reaction [Iohexol promotes the reaction [Glycerol results in increased expression of TNF mRNA]]; Carnitine inhibits the reaction [Iohexol promotes the reaction [Glycerol results in increased expression of TNF protein]]; Carnitine inhibits the reaction [Methotrexate results in increased expression of TNF protein] Carnitine results in decreased expression of TNF protein
|
CTD |
PMID:18597074 PMID:18629605 PMID:18852009 PMID:26562095 PMID:33965443 PMID:37312617 More...
|
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
|
|
G
|
Vim
|
vimentin
|
multiple interactions
|
EXP
|
Carnitine inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of VIM protein]
|
CTD |
PMID:28973641 |
|
NCBI chr17:81,577,261...81,585,746
Ensembl chr17:76,668,647...76,677,187
|
|
|
G
|
Epas1
|
endothelial PAS domain protein 1
|
increases expression multiple interactions
|
ISO
|
3,4-dihydroxybenzoate results in increased expression of EPAS1 mRNA [3,4-dihydroxybenzoate co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of EPAS1 mRNA
|
CTD |
PMID:19679656 |
|
NCBI chr 6:13,543,252...13,626,147
Ensembl chr 6:7,790,647...7,871,228
|
|
G
|
Hif1a
|
hypoxia inducible factor 1 subunit alpha
|
increases expression affects localization multiple interactions
|
ISO EXP
|
3,4-dihydroxybenzoate results in increased expression of HIF1A mRNA 3,4-dihydroxybenzoate affects the localization of HIF1A protein [3,4-dihydroxybenzoate co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine metabolite] affects the localization of HIF1A protein [3,4-dihydroxybenzoate co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of HIF1A mRNA
|
CTD |
PMID:19679656 |
|
NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:92,624,390...92,669,261
|
|
G
|
Hmox1
|
heme oxygenase 1
|
multiple interactions increases expression
|
ISO
|
[3,4-dihydroxybenzoate co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of HMOX1 mRNA; [3,4-dihydroxybenzoate co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of HMOX1 protein 3,4-dihydroxybenzoate results in increased expression of HMOX1 mRNA; 3,4-dihydroxybenzoate results in increased expression of HMOX1 protein
|
CTD |
PMID:19679656 |
|
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079
|
|
G
|
Slc40a1
|
solute carrier family 40 member 1
|
multiple interactions
|
ISO
|
3,4-dihydroxybenzoate inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of SLC40A1 protein]
|
CTD |
PMID:19679656 |
|
NCBI chr 9:55,525,457...55,633,463
Ensembl chr 9:48,033,526...48,051,481
|
|
G
|
Sod2
|
superoxide dismutase 2
|
multiple interactions increases expression
|
ISO
|
[3,4-dihydroxybenzoate co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of SOD2 protein 3,4-dihydroxybenzoate results in increased expression of SOD2 protein
|
CTD |
PMID:19679656 |
|
NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189
|
|
|
G
|
Bbox1
|
gamma-butyrobetaine hydroxylase 1
|
multiple interactions
|
ISO
|
[BBOX1 protein co-treated with Ketoglutaric Acids] results in increased metabolism of gamma-butyrobetaine
|
CTD |
PMID:21439360 |
|
NCBI chr 3:96,822,654...96,871,786
Ensembl chr 3:96,822,655...96,871,458
|
|
G
|
Idh2
|
isocitrate dehydrogenase (NADP(+)) 2
|
multiple interactions increases abundance
|
ISO
|
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of gamma-butyrobetaine]
|
CTD |
PMID:27469509 |
|
NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:134,029,772...134,058,025
|
|
|
G
|
A2m
|
alpha-2-macroglobulin
|
decreases expression
|
ISO
|
Aminocaproic Acid results in decreased expression of A2M protein
|
CTD |
PMID:11304663 |
|
NCBI chr 4:156,570,163...156,619,870
Ensembl chr 4:154,897,877...154,947,786
|
|
G
|
Folh1
|
folate hydrolase 1
|
multiple interactions
|
ISO
|
[2-(3-(1,3-dicarboxypropyl)ureido)pentanedioic acid binds to Aminocaproic Acid binds to 1-(1,3-carboxypropyl)-4,7-carboxymethyl-1,4,7-triazacyclononane binds to Valerates binds to bombesin (7-14) binds to Copper] inhibits the reaction [isospaglumic acid binds to FOLH1 protein]
|
CTD |
PMID:24508213 |
|
NCBI chr 1:140,428,101...140,501,563
Ensembl chr 1:140,428,101...140,501,379
|
|
G
|
Grpr
|
gastrin releasing peptide receptor
|
multiple interactions
|
ISO
|
[2-(3-(1,3-dicarboxypropyl)ureido)pentanedioic acid binds to Aminocaproic Acid binds to 1-(1,3-carboxypropyl)-4,7-carboxymethyl-1,4,7-triazacyclononane binds to Valerates binds to bombesin (7-14) binds to Copper] inhibits the reaction [bombesin, Tyr(4)- binds to GRPR protein]
|
CTD |
PMID:24508213 |
|
NCBI chr X:30,998,425...31,038,442
Ensembl chr X:30,998,416...31,038,442
|
|
G
|
Mapk1
|
mitogen activated protein kinase 1
|
multiple interactions
|
ISO
|
Aminocaproic Acid inhibits the reaction [PLG protein results in increased phosphorylation of MAPK1 protein]
|
CTD |
PMID:17482686 |
|
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616
|
|
G
|
Mapk3
|
mitogen activated protein kinase 3
|
multiple interactions
|
ISO
|
Aminocaproic Acid inhibits the reaction [PLG protein results in increased phosphorylation of MAPK3 protein]
|
CTD |
PMID:17482686 |
|
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863
|
|
G
|
Plg
|
plasminogen
|
multiple interactions
|
ISO
|
Aminocaproic Acid inhibits the reaction [PLG protein results in increased phosphorylation of MAPK1 protein]; Aminocaproic Acid inhibits the reaction [PLG protein results in increased phosphorylation of MAPK3 protein]
|
CTD |
PMID:17482686 |
|
NCBI chr 1:50,872,927...50,915,406
Ensembl chr 1:48,325,185...48,367,786
|
|
G
|
Serpinc1
|
serpin family C member 1
|
increases expression
|
ISO
|
Aminocaproic Acid results in increased expression of SERPINC1 protein
|
CTD |
PMID:11304663 |
|
NCBI chr13:75,790,558...75,804,826
Ensembl chr13:73,257,179...73,284,293
|
|
|
G
|
Tnf
|
tumor necrosis factor
|
increases secretion
|
EXP
|
Acetate increases secretion of Tnf protein from Kupffer cells
|
RGD |
PMID:19299582 |
RGD:9585771 |
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
|
|
|
G
|
Abcb11
|
ATP binding cassette subfamily B member 11
|
decreases expression
|
ISO
|
Amoxicillin-Potassium Clavulanate Combination results in decreased expression of ABCB11 mRNA
|
CTD |
PMID:34767876 |
|
NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:54,017,127...54,112,730
|
|
G
|
Akr1b10
|
aldo-keto reductase family 1 member B10
|
increases expression
|
ISO
|
Amoxicillin-Potassium Clavulanate Combination results in increased expression of AKR1B10 mRNA
|
CTD |
PMID:34767876 |
|
NCBI chr 4:64,005,632...64,027,860
Ensembl chr 4:63,040,169...63,053,852
|
|
G
|
Casp3
|
caspase 3
|
increases activity
|
EXP
|
Amoxicillin-Potassium Clavulanate Combination results in increased activity of CASP3 protein
|
CTD |
PMID:30273099 |
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648
|
|
G
|
Casp9
|
caspase 9
|
increases activity
|
EXP
|
Amoxicillin-Potassium Clavulanate Combination results in increased activity of CASP9 protein
|
CTD |
PMID:30273099 |
|
Ensembl chr 5:154,109,046...154,126,626
|
|
G
|
Cycs
|
cytochrome c, somatic
|
increases secretion
|
EXP
|
Amoxicillin-Potassium Clavulanate Combination results in increased secretion of CYCS protein
|
CTD |
PMID:30273099 |
|
NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
|
|
G
|
Cyp27a1
|
cytochrome P450, family 27, subfamily a, polypeptide 1
|
decreases expression
|
ISO
|
Amoxicillin-Potassium Clavulanate Combination results in decreased expression of CYP27A1 mRNA
|
CTD |
PMID:34767876 |
|
NCBI chr 9:83,712,402...83,743,222
Ensembl chr 9:76,264,860...76,294,551
|
|
G
|
Cyp7a1
|
cytochrome P450 family 7 subfamily A member 1
|
decreases expression
|
ISO
|
Amoxicillin-Potassium Clavulanate Combination results in decreased expression of CYP7A1 mRNA
|
CTD |
PMID:34767876 |
|
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
|
|
G
|
Cyp8b1
|
cytochrome P450 family 8 subfamily B member 1
|
decreases expression
|
ISO
|
Amoxicillin-Potassium Clavulanate Combination results in decreased expression of CYP8B1 mRNA
|
CTD |
PMID:34767876 |
|
NCBI chr 8:130,455,622...130,457,592
Ensembl chr 8:121,557,062...121,580,166
|
|
G
|
Fgf19
|
fibroblast growth factor 19
|
increases expression
|
ISO
|
Amoxicillin-Potassium Clavulanate Combination results in increased expression of FGF19 mRNA
|
CTD |
PMID:34767876 |
|
NCBI chr 1:209,485,813...209,490,267
Ensembl chr 1:200,056,644...200,060,287
|
|
G
|
G6pd
|
glucose-6-phosphate dehydrogenase
|
increases expression
|
ISO
|
Amoxicillin-Potassium Clavulanate Combination results in increased expression of G6PD mRNA
|
CTD |
PMID:34767876 |
|
NCBI chr X:157,352,364...157,372,144
Ensembl chr X:152,201,098...152,220,801
|
|
G
|
Gclc
|
glutamate-cysteine ligase, catalytic subunit
|
increases expression
|
ISO
|
Amoxicillin-Potassium Clavulanate Combination results in increased expression of GCLC mRNA
|
CTD |
PMID:34767876 |
|
NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:78,630,127...78,668,544
|
|
G
|
Gclm
|
glutamate cysteine ligase, modifier subunit
|
increases expression
|
ISO
|
Amoxicillin-Potassium Clavulanate Combination results in increased expression of GCLM mRNA
|
CTD |
PMID:34767876 |
|
NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:210,347,482...210,367,535
|
|
G
|
Ggt1
|
gamma-glutamyltransferase 1
|
increases expression
|
ISO
|
Amoxicillin-Potassium Clavulanate Combination results in increased expression of GGT1 protein
|
CTD |
PMID:34767876 |
|
NCBI chr20:13,074,141...13,103,551
Ensembl chr20:13,074,700...13,108,442
|
|
G
|
Got1
|
glutamic-oxaloacetic transaminase 1
|
increases activity
|
EXP
|
Amoxicillin-Potassium Clavulanate Combination results in increased activity of GOT1 protein
|
CTD |
PMID:30273099 |
|
NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:242,357,306...242,380,633
|
|
G
|
Gpt
|
glutamic--pyruvic transaminase
|
increases activity
|
EXP
|
Amoxicillin-Potassium Clavulanate Combination results in increased activity of GPT protein
|
CTD |
PMID:30273099 |
|
NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:108,416,642...108,419,494
|
|
G
|
Gpx2
|
glutathione peroxidase 2
|
increases expression
|
ISO
|
Amoxicillin-Potassium Clavulanate Combination results in increased expression of GPX2 mRNA
|
CTD |
PMID:34767876 |
|
NCBI chr 6:101,226,745...101,230,033
Ensembl chr 6:95,493,589...95,496,877
|
|
G
|
Gsr
|
glutathione-disulfide reductase
|
increases expression
|
ISO
|
Amoxicillin-Potassium Clavulanate Combination results in increased expression of GSR mRNA
|
CTD |
PMID:34767876 |
|
NCBI chr16:65,185,574...65,228,742
Ensembl chr16:58,482,505...58,525,661
|
|
G
|
Me1
|
malic enzyme 1
|
increases expression
|
ISO
|
Amoxicillin-Potassium Clavulanate Combination results in increased expression of ME1 mRNA
|
CTD |
PMID:34767876 |
|
NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
|
|
G
|
Nr0b2
|
nuclear receptor subfamily 0, group B, member 2
|
increases expression
|
ISO
|
Amoxicillin-Potassium Clavulanate Combination results in increased expression of NR0B2 mRNA
|
CTD |
PMID:34767876 |
|
NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609
|
|
G
|
Slc10a1
|
solute carrier family 10 member 1
|
decreases expression
|
ISO
|
Amoxicillin-Potassium Clavulanate Combination results in decreased expression of SLC10A1 mRNA
|
CTD |
PMID:34767876 |
|
NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670
|
|
G
|
Slc51a
|
solute carrier family 51 member A
|
decreases expression
|
ISO
|
Amoxicillin-Potassium Clavulanate Combination results in decreased expression of SLC51A mRNA
|
CTD |
PMID:34767876 |
|
NCBI chr11:68,299,086...68,313,485
Ensembl chr11:68,299,086...68,313,485
|
|
G
|
Slc7a11
|
solute carrier family 7 member 11
|
increases expression
|
ISO
|
Amoxicillin-Potassium Clavulanate Combination results in increased expression of SLC7A11 mRNA
|
CTD |
PMID:34767876 |
|
NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
|
|
G
|
Tkt
|
transketolase
|
increases expression
|
ISO
|
Amoxicillin-Potassium Clavulanate Combination results in increased expression of TKT mRNA
|
CTD |
PMID:34767876 |
|
NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,723,762...5,748,698
|
|
G
|
Txnrd1
|
thioredoxin reductase 1
|
increases expression
|
ISO
|
Amoxicillin-Potassium Clavulanate Combination results in increased expression of TXNRD1 mRNA
|
CTD |
PMID:34767876 |
|
NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:20,830,045...20,907,863
|
|
|
G
|
Ahcy
|
adenosylhomocysteinase
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of AHCY mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 3:143,569,134...143,584,359
Ensembl chr 3:143,569,094...143,584,393
|
|
G
|
Ahr
|
aryl hydrocarbon receptor
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of AHR mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568
|
|
G
|
Alcam
|
activated leukocyte cell adhesion molecule
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of ALCAM mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr11:61,804,932...62,005,250
Ensembl chr11:48,336,169...48,537,954
|
|
G
|
Anxa4
|
annexin A4
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of ANXA4 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 4:120,741,750...120,798,534
Ensembl chr 4:119,184,374...119,241,161
|
|
G
|
Batf3
|
basic leucine zipper ATF-like transcription factor 3
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of BATF3 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr13:105,220,782...105,232,365
Ensembl chr13:102,689,657...102,701,139
|
|
G
|
Bcl2
|
BCL2, apoptosis regulator
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of BCL2 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
|
|
G
|
Bmp2
|
bone morphogenetic protein 2
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of BMP2 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:120,812,882...120,821,397
|
|
G
|
Capg
|
capping actin protein, gelsolin like
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of CAPG mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856
|
|
G
|
Casp3
|
caspase 3
|
increases expression decreases expression
|
ISO
|
Benzoates analog results in increased expression of CASP3 protein modified form Benzoates analog results in decreased expression of CASP3 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648
|
|
G
|
Ccnd2
|
cyclin D2
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of CCND2 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 4:161,653,048...161,675,422
Ensembl chr 4:159,962,363...159,989,495
|
|
G
|
Ccnd3
|
cyclin D3
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of CCND3 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 9:20,891,696...20,987,199
Ensembl chr 9:13,394,169...13,489,371
|
|
G
|
Ccne1
|
cyclin E1
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of CCNE1 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:90,781,949...90,791,101
|
|
G
|
Cd44
|
CD44 molecule
|
affects expression
|
ISO
|
Benzoates analog affects the expression of CD44 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:89,157,058...89,244,620
|
|
G
|
Cd48
|
Cd48 molecule
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of CD48 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr13:84,184,884...84,209,144
Ensembl chr13:84,185,532...84,209,142
|
|
G
|
Cd81
|
Cd81 molecule
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of CD81 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 1:207,665,274...207,681,094
Ensembl chr 1:198,241,484...198,251,660
|
|
G
|
Cdc42se2
|
CDC42 small effector 2
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of CDC42SE2 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr10:38,836,549...38,905,056
Ensembl chr10:38,836,555...38,905,059 Ensembl chr 1:38,836,555...38,905,059
|
|
G
|
Cdc6
|
cell division cycle 6
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of CDC6 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr10:84,360,361...84,374,239
Ensembl chr10:83,864,638...83,878,011
|
|
G
|
Cish
|
cytokine inducible SH2-containing protein
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of CISH mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 8:116,850,969...116,855,917
Ensembl chr 8:107,972,306...107,977,250
|
|
G
|
Ckap4
|
cytoskeleton-associated protein 4
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of CKAP4 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 7:19,230,814...19,238,914
Ensembl chr 7:19,230,203...19,238,914
|
|
G
|
Csf1
|
colony stimulating factor 1
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of CSF1 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 2:198,065,400...198,084,774
Ensembl chr 2:195,377,215...195,411,704
|
|
G
|
Cst7
|
cystatin F
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of CST7 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 3:139,396,830...139,405,557
Ensembl chr 3:139,396,850...139,405,557
|
|
G
|
Ctsz
|
cathepsin Z
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of CTSZ mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 3:163,224,875...163,235,645
Ensembl chr 3:163,224,875...163,235,645
|
|
G
|
Cxcl10
|
C-X-C motif chemokine ligand 10
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of CXCL10 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
|
|
G
|
Cxcl2
|
C-X-C motif chemokine ligand 2
|
increases expression decreases expression
|
ISO
|
Benzoates results in increased expression of CXCL2 protein Benzoates results in decreased expression of CXCL2 protein
|
CTD |
PMID:23178550 |
|
NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,181,062...17,183,075
|
|
G
|
Cyfip1
|
cytoplasmic FMR1 interacting protein 1
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of CYFIP1 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 1:106,710,924...106,799,393
Ensembl chr 1:106,711,016...106,799,386
|
|
G
|
Dcps
|
decapping enzyme, scavenger
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of DCPS mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 8:33,468,669...33,524,407
Ensembl chr 8:33,415,671...33,524,389
|
|
G
|
Dennd5a
|
DENN domain containing 5A
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of DENND5A mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 1:163,928,183...163,994,207
Ensembl chr 1:163,928,183...163,994,316
|
|
G
|
Dhrs3
|
dehydrogenase/reductase 3
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of DHRS3 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 5:162,031,853...162,065,655
Ensembl chr 5:156,747,962...156,782,417
|
|
G
|
Ecm1
|
extracellular matrix protein 1
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of ECM1 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 2:183,287,491...183,292,729
Ensembl chr 2:183,287,322...183,292,671
|
|
G
|
Eef1akmt1
|
EEF1A lysine methyltransferase 1
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of EEF1AKMT1 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr15:31,694,284...31,711,367
Ensembl chr15:31,694,292...31,711,336
|
|
G
|
Emp1
|
epithelial membrane protein 1
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of EMP1 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 4:168,212,901...168,233,039
Ensembl chr 4:168,212,861...168,232,904
|
|
G
|
Esr1
|
estrogen receptor 1
|
increases activity
|
ISO
|
Benzoates results in increased activity of ESR1 protein
|
CTD |
PMID:16756374 |
|
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002
|
|
G
|
Etv4
|
ETS variant transcription factor 4
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of ETV4 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr10:87,206,977...87,222,202
Ensembl chr10:86,706,749...86,721,974
|
|
G
|
Fah
|
fumarylacetoacetate hydrolase
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of FAH mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 1:147,957,931...147,980,708
Ensembl chr 1:138,548,834...138,571,505
|
|
G
|
Fgl2
|
fibrinogen-like 2
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of FGL2 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 4:14,602,762...14,608,405
Ensembl chr 4:13,710,575...13,716,207
|
|
G
|
Flt3
|
Fms related receptor tyrosine kinase 3
|
increases response to substance
|
ISO
|
FLT3 protein mutant form results in increased susceptibility to Benzoates analog
|
CTD |
PMID:29472718 |
|
NCBI chr12:12,660,035...12,735,584
Ensembl chr12:7,623,930...7,699,474
|
|
G
|
Gabarapl1
|
GABA type A receptor associated protein like 1
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of GABARAPL1 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 4:164,666,332...164,675,474
Ensembl chr 4:162,980,249...162,989,450
|
|
G
|
Gadd45b
|
growth arrest and DNA-damage-inducible, beta
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of GADD45B mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 7:9,428,689...9,430,991
Ensembl chr 7:8,778,007...8,780,046
|
|
G
|
Galm
|
galactose mutarotase
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of GALM mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 6:14,837,540...14,889,484
Ensembl chr 6:14,837,548...14,889,310
|
|
G
|
Gbp4
|
guanylate binding protein 4
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of GBP4 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 2:231,304,910...231,318,883
Ensembl chr 2:231,305,244...231,318,879
|
|
G
|
Gh1
|
growth hormone 1
|
multiple interactions
|
ISO
|
Benzoates analog inhibits the reaction [GH protein promotes the reaction [STAT5A protein binds to STAT5A protein]]; Benzoates analog inhibits the reaction [GH protein results in increased phosphorylation of STAT5A protein]
|
CTD |
PMID:29472718 |
|
NCBI chr10:91,727,883...91,729,860
Ensembl chr10:91,228,103...91,230,078
|
|
G
|
Gpd1
|
glycerol-3-phosphate dehydrogenase 1
|
multiple interactions
|
ISO
|
[INS1 protein co-treated with Benzoates] results in increased activity of GPD1 protein
|
CTD |
PMID:2523799 |
|
NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529
|
|
G
|
Gpx4
|
glutathione peroxidase 4
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of GPX4 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
|
|
G
|
Gria1
|
glutamate ionotropic receptor AMPA type subunit 1
|
multiple interactions
|
EXP
|
Benzoates analog binds to and results in decreased activity of GRIA1 protein
|
CTD |
PMID:14667236 |
|
NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283
|
|
G
|
Gria2
|
glutamate ionotropic receptor AMPA type subunit 2
|
multiple interactions
|
EXP
|
Benzoates analog binds to and results in decreased activity of GRIA2 protein
|
CTD |
PMID:14667236 |
|
NCBI chr 2:168,247,490...168,367,616
Ensembl chr 2:165,947,521...166,069,510
|
|
G
|
Gria3
|
glutamate ionotropic receptor AMPA type subunit 3
|
multiple interactions
|
EXP
|
Benzoates analog binds to and results in decreased activity of GRIA3 protein
|
CTD |
PMID:14667236 |
|
NCBI chr X:125,103,975...125,369,690
Ensembl chr X:120,238,534...120,504,096
|
|
G
|
Gria4
|
glutamate ionotropic receptor AMPA type subunit 4
|
multiple interactions
|
EXP
|
Benzoates analog binds to and results in decreased activity of GRIA4 protein
|
CTD |
PMID:14667236 |
|
NCBI chr 8:9,845,421...10,320,021
Ensembl chr 8:1,562,119...2,034,979
|
|
G
|
Grik1
|
glutamate ionotropic receptor kainate type subunit 1
|
multiple interactions
|
ISO
|
Benzoates analog binds to and results in decreased activity of GRIK1 protein
|
CTD |
PMID:14667236 |
|
NCBI chr11:27,169,739...27,571,131
Ensembl chr11:27,169,740...27,570,645
|
|
G
|
Grik2
|
glutamate ionotropic receptor kainate type subunit 2
|
multiple interactions
|
ISO
|
Benzoates analog binds to and results in decreased activity of GRIK2 protein
|
CTD |
PMID:14667236 |
|
NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375
|
|
G
|
Gsto1
|
glutathione S-transferase omega 1
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of GSTO1 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 1:256,662,377...256,672,515
Ensembl chr 1:246,721,221...246,731,468
|
|
G
|
Hk2
|
hexokinase 2
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of HK2 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 4:116,792,258...116,841,275
Ensembl chr 4:115,234,509...115,283,530
|
|
G
|
Ifitm3
|
interferon induced transmembrane protein 3
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of IFITM3 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 1:196,111,026...196,112,135
Ensembl chr 1:196,111,043...196,112,203
|
|
G
|
Ifngr1
|
interferon gamma receptor 1
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of IFNGR1 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 1:16,152,811...16,171,439
Ensembl chr 1:14,333,187...14,351,785
|
|
G
|
Il10ra
|
interleukin 10 receptor subunit alpha
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of IL10RA mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 8:54,459,754...54,474,786
Ensembl chr 8:45,563,137...45,578,061
|
|
G
|
Il1a
|
interleukin 1 alpha
|
increases expression
|
ISO
|
Benzoates results in increased expression of IL1A protein
|
CTD |
PMID:23178550 |
|
NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:116,526,604...116,536,822
|
|
G
|
Il2rb
|
interleukin 2 receptor subunit beta
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of IL2RB mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 7:111,913,828...111,928,537
Ensembl chr 7:110,033,341...110,048,054
|
|
G
|
Il3
|
interleukin 3
|
multiple interactions
|
ISO
|
Benzoates analog inhibits the reaction [IL3 protein results in increased activity of STAT5A protein]
|
CTD |
PMID:29472718 |
|
NCBI chr10:38,906,460...38,908,810
Ensembl chr10:38,405,716...38,408,066
|
|
G
|
Il4r
|
interleukin 4 receptor
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of IL4R mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 1:189,545,739...189,570,639
Ensembl chr 1:180,115,120...180,139,980
|
|
G
|
Il6
|
interleukin 6
|
multiple interactions
|
ISO
|
Benzoates analog inhibits the reaction [IL6 protein results in increased activity of STAT3 protein]
|
CTD |
PMID:29472718 |
|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178
|
|
G
|
Ins1
|
insulin 1
|
multiple interactions
|
ISO
|
[INS1 protein co-treated with Benzoates] results in increased activity of GPD1 protein
|
CTD |
PMID:2523799 |
|
NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:251,244,973...251,245,536
|
|
G
|
Irf4
|
interferon regulatory factor 4
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of IRF4 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr17:33,930,460...33,948,842
Ensembl chr17:33,721,811...33,740,070
|
|
G
|
Irf8
|
interferon regulatory factor 8
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of IRF8 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr19:65,699,284...65,721,066
Ensembl chr19:48,790,588...48,811,829
|
|
G
|
Itga6
|
integrin subunit alpha 6
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of ITGA6 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 3:56,604,512...56,689,428
Ensembl chr 3:56,617,268...56,689,428
|
|
G
|
Klf6
|
KLF transcription factor 6
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of KLF6 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
|
|
G
|
Lif
|
LIF, interleukin 6 family cytokine
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of LIF mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr14:83,354,602...83,364,053
Ensembl chr14:79,134,574...79,140,482
|
|
G
|
Map3k8
|
mitogen-activated protein kinase kinase kinase 8
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of MAP3K8 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr17:58,078,175...58,098,455
Ensembl chr17:53,383,131...53,403,216
|
|
G
|
Mapkapk2
|
MAPK activated protein kinase 2
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of MAPKAPK2 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr13:45,066,027...45,112,326
Ensembl chr13:42,513,762...42,560,457
|
|
G
|
Mki67
|
marker of proliferation Ki-67
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of MKI67 protein
|
CTD |
PMID:29472718 |
|
NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:190,496,319...190,522,762
|
|
G
|
Mxd1
|
max dimerization protein 1
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of MXD1 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 4:119,097,353...119,118,080
Ensembl chr 4:119,097,353...119,117,751
|
|
G
|
Myc
|
MYC proto-oncogene, bHLH transcription factor
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of MYC mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630
|
|
G
|
Myo1c
|
myosin 1C
|
affects expression
|
ISO
|
Benzoates analog affects the expression of MYO1C mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr10:60,996,642...61,019,022
Ensembl chr10:60,498,280...60,520,752
|
|
G
|
Ncoa3
|
nuclear receptor coactivator 3
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of NCOA3 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 3:154,738,566...154,821,395
Ensembl chr 3:154,738,581...154,818,594
|
|
G
|
Ncs1
|
neuronal calcium sensor 1
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of NCS1 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 3:34,920,949...34,966,554
Ensembl chr 3:14,523,220...14,568,829
|
|
G
|
Ndrg1
|
N-myc downstream regulated 1
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of NDRG1 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 7:100,573,526...100,614,902
Ensembl chr 7:98,684,487...98,725,880
|
|
G
|
Nfil3
|
nuclear factor, interleukin 3 regulated
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of NFIL3 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr17:12,432,376...12,447,605
Ensembl chr17:12,280,484...12,295,858
|
|
G
|
Nfkbiz
|
NFKB inhibitor zeta
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of NFKBIZ mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr11:58,251,720...58,279,767
Ensembl chr11:44,782,676...44,810,723
|
|
G
|
Nop2
|
NOP2 nucleolar protein
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of NOP2 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 4:157,932,731...157,944,462
Ensembl chr 4:157,932,716...157,944,459
|
|
G
|
Odc1
|
ornithine decarboxylase 1
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of ODC1 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
|
|
G
|
P2rx4
|
purinergic receptor P2X 4
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of P2RX4 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr12:33,844,609...33,862,265
Ensembl chr12:33,844,396...33,862,253
|
|
G
|
P4ha1
|
prolyl 4-hydroxylase subunit alpha 1
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of P4HA1 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr20:27,784,696...27,895,785
Ensembl chr20:27,302,141...27,352,786
|
|
G
|
Parp1
|
poly (ADP-ribose) polymerase 1
|
increases cleavage
|
ISO
|
Benzoates analog results in increased cleavage of PARP1 protein
|
CTD |
PMID:29472718 |
|
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:92,307,586...92,339,404
|
|
G
|
Pdgfrb
|
platelet derived growth factor receptor beta
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of PDGFRB protein
|
CTD |
PMID:29472718 |
|
NCBI chr18:56,770,348...56,809,228
Ensembl chr18:54,499,964...54,538,843
|
|
G
|
Phlda1
|
pleckstrin homology-like domain, family A, member 1
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of PHLDA1 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 7:48,853,690...48,855,894
Ensembl chr 7:46,967,409...46,969,861
|
|
G
|
Phtf2
|
putative homeodomain transcription factor 2
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of PHTF2 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 4:14,215,190...14,330,549
Ensembl chr 4:14,215,263...14,330,513
|
|
G
|
Pim1
|
Pim-1 proto-oncogene, serine/threonine kinase
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of PIM1 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr20:7,556,496...7,560,747
Ensembl chr20:7,554,921...7,559,174
|
|
G
|
Plin2
|
perilipin 2
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of PLIN2 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
|
|
G
|
Plscr1
|
phospholipid scramblase 1
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of PLSCR1 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 8:101,662,512...101,684,474
Ensembl chr 8:92,784,356...92,804,692
|
|
G
|
Pnp
|
purine nucleoside phosphorylase
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of PNP mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr15:26,644,147...26,651,808
Ensembl chr15:24,170,602...24,203,986
|
|
G
|
Prnp
|
prion protein
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of PRNP mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 3:139,639,076...139,654,420
Ensembl chr 3:119,177,485...119,203,937
|
|
G
|
Ptch1
|
patched 1
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of PTCH1 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr17:1,548,449...1,613,461
Ensembl chr17:1,542,877...1,607,333
|
|
G
|
Ptrh2
|
peptidyl-tRNA hydrolase 2
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of PTRH2 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr10:71,505,113...71,515,297
Ensembl chr10:71,504,956...71,515,398
|
|
G
|
Pus1
|
pseudouridine synthase 1
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of PUS1 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr12:45,880,364...45,889,196
Ensembl chr12:45,880,440...45,889,196
|
|
G
|
Rabgap1l
|
RAB GTPase activating protein 1-like
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of RABGAP1L mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr13:72,464,114...73,059,845
Ensembl chr13:72,468,110...73,059,984
|
|
G
|
Rgs16
|
regulator of G-protein signaling 16
|
affects expression
|
ISO
|
Benzoates analog affects the expression of RGS16 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr13:65,887,668...65,892,862
Ensembl chr13:65,887,530...65,892,857
|
|
G
|
Rhoh
|
ras homolog family member H
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of RHOH mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr14:42,694,860...42,725,690
Ensembl chr14:42,337,751...42,386,369
|
|
G
|
Rragd
|
Ras-related GTP binding D
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of RRAGD mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 5:47,373,902...47,409,369
Ensembl chr 5:47,373,463...47,409,356
|
|
G
|
Sh3bgrl2
|
SH3 domain binding glutamate-rich protein like 2
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of SH3BGRL2 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 8:84,461,019...84,553,124
Ensembl chr 8:84,461,121...84,551,564
|
|
G
|
Slc1a5
|
solute carrier family 1 member 5
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of SLC1A5 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 1:86,584,949...86,599,052
Ensembl chr 1:77,456,694...77,470,952
|
|
G
|
Slc2a3
|
solute carrier family 2 member 3
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of SLC2A3 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 4:157,632,887...157,698,034
Ensembl chr 4:155,960,946...156,025,472
|
|
G
|
Slc39a8
|
solute carrier family 39 member 8
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of SLC39A8 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 2:226,845,686...226,992,668
Ensembl chr 2:224,256,654...224,319,129
|
|
G
|
Smpdl3a
|
sphingomyelin phosphodiesterase, acid-like 3A
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of SMPDL3A mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr20:37,132,592...37,155,567
Ensembl chr20:37,132,592...37,155,567
|
|
G
|
Snx9
|
sorting nexin 9
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of SNX9 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 1:46,424,897...46,510,096
Ensembl chr 1:46,423,553...46,509,036
|
|
G
|
Socs2
|
suppressor of cytokine signaling 2
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of SOCS2 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 7:31,890,564...31,932,092
Ensembl chr 7:30,008,578...30,043,548
|
|
G
|
Spred2
|
sprouty-related, EVH1 domain containing 2
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of SPRED2 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr14:98,350,577...98,452,143
Ensembl chr14:94,148,837...94,249,162
|
|
G
|
St3gal4
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
|
affects expression
|
ISO
|
Benzoates analog affects the expression of ST3GAL4 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 8:41,673,510...41,723,158
Ensembl chr 8:33,415,671...33,524,389
|
|
G
|
Stat3
|
signal transducer and activator of transcription 3
|
multiple interactions
|
ISO
|
Benzoates analog inhibits the reaction [IL6 protein results in increased activity of STAT3 protein]
|
CTD |
PMID:29472718 |
|
NCBI chr10:86,311,528...86,363,513
Ensembl chr10:85,811,218...85,863,057
|
|
G
|
Stat5a
|
signal transducer and activator of transcription 5A
|
decreases phosphorylation multiple interactions
|
ISO
|
Benzoates analog results in decreased phosphorylation of STAT5A protein Benzoates analog inhibits the reaction [GH protein promotes the reaction [STAT5A protein binds to STAT5A protein]]; Benzoates analog inhibits the reaction [GH protein results in increased phosphorylation of STAT5A protein]; Benzoates analog inhibits the reaction [IL3 protein results in increased activity of STAT5A protein]
|
CTD |
PMID:29472718 |
|
NCBI chr10:86,285,859...86,310,187
Ensembl chr10:85,785,537...85,809,866
|
|
G
|
Stat5b
|
signal transducer and activator of transcription 5B
|
multiple interactions
|
ISO
|
Benzoates analog binds to and results in decreased phosphorylation of STAT5B protein
|
CTD |
PMID:29472718 |
|
NCBI chr10:86,205,148...86,276,178
Ensembl chr10:85,705,670...85,775,668
|
|
G
|
Swap70
|
switching B-cell complex subunit SWAP70
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of SWAP70 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 1:164,267,588...164,328,796
Ensembl chr 1:164,267,609...164,328,794
|
|
G
|
Syt11
|
synaptotagmin 11
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of SYT11 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 2:174,206,032...174,232,540
Ensembl chr 2:174,206,191...174,231,964
|
|
G
|
Tgm2
|
transglutaminase 2
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of TGM2 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981
|
|
G
|
Tiam1
|
TIAM Rac1 associated GEF 1
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of TIAM1 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr11:29,031,347...29,380,153
Ensembl chr11:29,031,348...29,159,901
|
|
G
|
Tnfrsf1b
|
TNF receptor superfamily member 1B
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of TNFRSF1B mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 5:162,356,250...162,387,411
Ensembl chr 5:157,070,642...157,104,206
|
|
G
|
Tnfrsf21
|
TNF receptor superfamily member 21
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of TNFRSF21 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 9:25,376,400...25,451,323
Ensembl chr 9:17,879,156...17,954,085
|
|
G
|
Traf1
|
TNF receptor-associated factor 1
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of TRAF1 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 3:18,222,024...18,242,163
Ensembl chr 3:18,222,054...18,241,807
|
|
G
|
Ttc39b
|
tetratricopeptide repeat domain 39B
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of TTC39B mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr 5:97,603,329...97,708,103
Ensembl chr 5:97,609,392...97,736,270
|
|
G
|
Uck2
|
uridine-cytidine kinase 2
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of UCK2 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr13:79,380,807...79,438,121
Ensembl chr13:79,383,846...79,438,352
|
|
G
|
Umps
|
uridine monophosphate synthetase
|
decreases expression
|
ISO
|
Benzoates analog results in decreased expression of UMPS mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr11:66,806,107...66,816,520
Ensembl chr11:66,806,045...66,821,903
|
|
G
|
Xbp1
|
X-box binding protein 1
|
increases expression
|
ISO
|
Benzoates analog results in increased expression of XBP1 mRNA
|
CTD |
PMID:29472718 |
|
NCBI chr14:84,604,623...84,609,707
Ensembl chr14:80,390,643...80,395,693
|
|
|
G
|
Slc22a5
|
solute carrier family 22 member 5
|
affects binding increases uptake multiple interactions increases transport
|
ISO EXP
|
pivaloylcarnitine binds to SLC22A5 protein SLC22A5 protein results in increased uptake of pivaloylcarnitine Carnitine inhibits the reaction [SLC22A5 protein results in increased transport of pivaloylcarnitine]; pivaloylcarnitine inhibits the reaction [SLC22A5 protein results in increased transport of Carnitine]
|
CTD |
PMID:18762717 PMID:19539806 |
|
NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309
|
|
|
G
|
Acacb
|
acetyl-CoA carboxylase beta
|
decreases expression
|
EXP
|
L-carnitine decreases expression of Acacb mRNA and protein in rat heart
|
RGD |
PMID:30644033 |
RGD:329955369 |
NCBI chr12:48,026,394...48,138,214
Ensembl chr12:42,366,548...42,457,655
|
|
G
|
Cpt1a
|
carnitine palmitoyltransferase 1A
|
increases expression multiple interactions
|
EXP
|
L-carnitine increases expression of Cpt1a mRNA and protein in rat heart L-carnitine inhibits the reaction [sunitinib decreases expression of Cpt1a mRNA and protein in rat heart]
|
RGD |
PMID:30644033 PMID:30644033 |
RGD:329955369, RGD:329955369 |
NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:200,565,613...200,627,055
|
|
G
|
Mlycd
|
malonyl-CoA decarboxylase
|
increases expression multiple interactions
|
EXP
|
L-carnitine increases expression of Mlycd protein in rat heart L-carnitine inhibits the reaction [sunitinib increases expression of Mlycd protein in rat heart]
|
RGD |
PMID:30644033 PMID:30644033 |
RGD:329955369, RGD:329955369 |
NCBI chr19:64,356,582...64,372,447
Ensembl chr19:47,447,970...47,463,793
|
|
G
|
Prkaa2
|
protein kinase AMP-activated catalytic subunit alpha 2
|
increases expression multiple interactions
|
EXP
|
L-carnitine increases expression of Ampka2 protein in rat serum and heart L-carnitine inhibits the reaction [sunitinib decreases expression of Ampka2 protein in rat serum and heart]
|
RGD |
PMID:30644033 PMID:30644033 |
RGD:329955369, RGD:329955369 |
NCBI chr 5:125,036,945...125,109,010
Ensembl chr 5:119,813,226...119,879,543
|
|
|
G
|
Gpt
|
glutamic--pyruvic transaminase
|
increases secretion
|
EXP
|
chlorhexidine gluconate results in increased secretion of GPT protein
|
CTD |
PMID:145039 |
|
NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:108,416,642...108,419,494
|
|
|
G
|
A2m
|
alpha-2-macroglobulin
|
multiple interactions
|
EXP
|
[cocoa butter co-treated with Cholesterol, Dietary co-treated with Cholates] results in increased expression of A2M mRNA; [cocoa butter co-treated with Cholesterol, Dietary co-treated with Cholates] results in increased expression of A2M protein
|
CTD |
PMID:25814186 |
|
NCBI chr 4:156,570,163...156,619,870
Ensembl chr 4:154,897,877...154,947,786
|
|
G
|
Abcb11
|
ATP binding cassette subfamily B member 11
|
increases expression decreases activity multiple interactions
|
ISO
|
Cholates results in increased expression of ABCB11 mRNA Cholates results in decreased activity of ABCB11 protein Cholates inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
|
CTD |
PMID:14684751 PMID:24014644 |
|
NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:54,017,127...54,112,730
|
|
G
|
Abcc3
|
ATP binding cassette subfamily C member 3
|
increases activity
|
ISO
|
Cholates results in increased activity of ABCC3 protein
|
CTD |
PMID:17569508 |
|
NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,296,693...79,342,595
|
|
G
|
Abcg5
|
ATP binding cassette subfamily G member 5
|
multiple interactions increases expression
|
ISO
|
Cholates promotes the reaction [ABCG5 protein results in increased secretion of Cholesterol] Cholates results in increased expression of ABCG5 mRNA; Cholates results in increased expression of ABCG5 protein
|
CTD |
PMID:15611112 |
|
NCBI chr 6:15,717,936...15,743,376
Ensembl chr 6:9,965,118...9,990,563
|
|
G
|
Abcg8
|
ATP binding cassette subfamily G member 8
|
multiple interactions increases expression
|
ISO
|
Cholates promotes the reaction [ABCG8 protein results in increased secretion of Cholesterol] Cholates results in increased expression of ABCG8 mRNA; Cholates results in increased expression of ABCG8 protein
|
CTD |
PMID:15611112 |
|
NCBI chr 6:15,698,448...15,717,730
Ensembl chr 6:9,945,629...9,964,912
|
|
G
|
Col1a1
|
collagen type I alpha 1 chain
|
multiple interactions
|
EXP
|
[cocoa butter co-treated with Cholesterol, Dietary co-treated with Cholates] results in increased expression of COL1A1 mRNA; resveratrol inhibits the reaction [[cocoa butter co-treated with Cholesterol, Dietary co-treated with Cholates] results in increased expression of COL1A1 mRNA]
|
CTD |
PMID:25814186 |
|
NCBI chr10:80,380,458...80,397,461
Ensembl chr10:79,883,622...79,900,624
|
|
G
|
Cyp7a1
|
cytochrome P450 family 7 subfamily A member 1
|
decreases expression
|
ISO
|
Cholates results in decreased expression of CYP7A1 mRNA
|
CTD |
PMID:10809780 PMID:14684751 |
|
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
|
|
G
|
Mapk8
|
mitogen-activated protein kinase 8
|
increases phosphorylation
|
ISO
|
Cholates results in increased phosphorylation of MAPK8 protein
|
CTD |
PMID:15750181 |
|
NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,638,924...8,721,981
|
|
G
|
Nr1h4
|
nuclear receptor subfamily 1, group H, member 4
|
increases activity increases expression
|
ISO
|
Cholates results in increased activity of NR1H4 protein Cholates results in increased expression of NR1H4 protein
|
CTD |
PMID:14684751 |
|
NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:23,846,122...23,942,047
|
|
G
|
Ppargc1a
|
PPARG coactivator 1 alpha
|
multiple interactions
|
EXP
|
[cocoa butter co-treated with Cholesterol, Dietary co-treated with Cholates] results in increased expression of PPARGC1A mRNA
|
CTD |
PMID:25814186 |
|
NCBI chr14:63,073,505...63,729,215
Ensembl chr14:58,861,144...59,512,656
|
|
G
|
Slc19a1
|
solute carrier family 19 member 1
|
decreases activity multiple interactions
|
EXP
|
Cholates results in decreased activity of SLC19A1 protein Cholates inhibits the reaction [SLC19A1 protein affects the transport of Methotrexate]
|
CTD |
PMID:14612385 |
|
NCBI chr20:11,584,410...11,602,429
Ensembl chr20:11,584,411...11,601,972
|
|
G
|
Slc22a8
|
solute carrier family 22 member 8
|
multiple interactions
|
ISO
|
Cholates inhibits the reaction [SLC22A8 protein affects the transport of estrone sulfate]
|
CTD |
PMID:11306713 |
|
NCBI chr 1:214,925,506...214,945,516
Ensembl chr 1:205,498,084...205,517,450
|
|
G
|
Srebf1
|
sterol regulatory element binding transcription factor 1
|
multiple interactions
|
EXP
|
[cocoa butter co-treated with Cholesterol, Dietary co-treated with Cholates] results in increased expression of SREBF1 mRNA
|
CTD |
PMID:25814186 |
|
NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,007,637...45,029,650
|
|
G
|
Tgfb1
|
transforming growth factor, beta 1
|
multiple interactions
|
EXP
|
[cocoa butter co-treated with Cholesterol, Dietary co-treated with Cholates] results in increased expression of TGFB1 mRNA
|
CTD |
PMID:25814186 |
|
NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847
|
|
G
|
Tnf
|
tumor necrosis factor
|
multiple interactions
|
EXP
|
[cocoa butter co-treated with Cholesterol, Dietary co-treated with Cholates] results in increased expression of TNF mRNA
|
CTD |
PMID:25814186 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
|
|
G
|
Tnfaip3
|
TNF alpha induced protein 3
|
multiple interactions
|
EXP
|
[cocoa butter co-treated with Cholesterol, Dietary co-treated with Cholates] results in increased expression of TNFAIP3 protein; resveratrol inhibits the reaction [[cocoa butter co-treated with Cholesterol, Dietary co-treated with Cholates] results in increased expression of TNFAIP3 protein]
|
CTD |
PMID:25814186 |
|
NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
|
|
|
G
|
Iyd
|
iodotyrosine deiodinase
|
multiple interactions
|
ISO
|
Eosine Yellowish-(YS) inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine]
|
CTD |
PMID:33352258 |
|
NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
|
|
|
G
|
Abcb1a
|
ATP binding cassette subfamily B member 1A
|
decreases activity
|
ISO
|
Erythrosine results in decreased activity of ABCB1 protein
|
CTD |
PMID:20041016 |
|
NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:25,158,362...25,442,709
|
|
G
|
Casp9
|
caspase 9
|
multiple interactions
|
EXP
|
[Tartrazine co-treated with Erythrosine] affects the expression of CASP9 mRNA
|
CTD |
PMID:32981412 |
|
Ensembl chr 5:154,109,046...154,126,626
|
|
G
|
Ccnd1
|
cyclin D1
|
increases expression
|
ISO
|
Erythrosine results in increased expression of CCND1 protein
|
CTD |
PMID:8927716 |
|
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602
|
|
G
|
Cdk2
|
cyclin dependent kinase 2
|
increases activity
|
ISO
|
Erythrosine results in increased activity of CDK2 protein
|
CTD |
PMID:8927716 PMID:9168006 |
|
NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,129,811...1,137,403
|
|
G
|
Cyp19a1
|
cytochrome P450, family 19, subfamily a, polypeptide 1
|
decreases activity
|
EXP
|
Erythrosine results in decreased activity of CYP19A1 protein
|
CTD |
PMID:18310892 |
|
NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:54,553,165...54,580,758
|
|
G
|
Cyp3a2
|
cytochrome P450, family 3, subfamily a, polypeptide 2
|
decreases activity
|
ISO
|
Erythrosine results in decreased activity of CYP3A4 protein
|
CTD |
PMID:20041016 |
|
NCBI chr12:14,321,771...14,343,886
Ensembl chr12:9,015,383...9,285,008
|
|
G
|
Fosl1
|
FOS like 1, AP-1 transcription factor subunit
|
increases expression
|
ISO
|
Erythrosine results in increased expression of FOSL1 protein
|
CTD |
PMID:20025956 |
|
NCBI chr 1:212,183,885...212,192,391
Ensembl chr 1:202,754,529...202,764,930
|
|
G
|
Gstp1
|
glutathione S-transferase pi 1
|
multiple interactions
|
ISO
|
Erythrosine inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate]
|
CTD |
PMID:23769903 |
|
NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226
|
|
G
|
Havcr1
|
hepatitis A virus cellular receptor 1
|
multiple interactions
|
EXP
|
[Tartrazine co-treated with Erythrosine] affects the expression of HAVCR1 mRNA
|
CTD |
PMID:32981412 |
|
NCBI chr10:31,619,914...31,652,955
Ensembl chr10:31,119,088...31,151,698
|
|
G
|
Hpgds
|
hematopoietic prostaglandin D synthase
|
decreases activity
|
ISO
|
Erythrosine results in decreased activity of HPGDS protein
|
CTD |
PMID:25603235 |
|
NCBI chr 4:95,698,265...95,727,733
Ensembl chr 4:94,373,342...94,397,883
|
|
G
|
Iyd
|
iodotyrosine deiodinase
|
decreases activity
|
ISO
|
Erythrosine results in decreased activity of IYD protein
|
CTD |
PMID:24012475 |
|
NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
|
|
G
|
Jun
|
Jun proto-oncogene, AP-1 transcription factor subunit
|
increases expression
|
ISO
|
Erythrosine results in increased expression of JUN protein
|
CTD |
PMID:20025956 |
|
NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656
|
|
G
|
Orm1
|
orosomucoid 1
|
increases expression
|
ISO
|
Erythrosine results in increased expression of ORM1 protein
|
CTD |
PMID:20025956 |
|
NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154
|
|
G
|
Phex
|
phosphate regulating endopeptidase X-linked
|
increases expression
|
ISO
|
Erythrosine results in increased expression of PHEX protein
|
CTD |
PMID:20025956 |
|
NCBI chr X:37,607,553...37,856,183
Ensembl chr X:37,610,760...37,854,469
|
|
G
|
Tnf
|
tumor necrosis factor
|
multiple interactions
|
EXP
|
[Tartrazine co-treated with Erythrosine] results in increased expression of TNF mRNA
|
CTD |
PMID:32981412 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
|
|
G
|
Tp53
|
tumor protein p53
|
increases activity
|
ISO
|
Erythrosine results in increased activity of TP53 protein
|
CTD |
PMID:9168006 |
|
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524
|
|
G
|
Trh
|
thyrotropin releasing hormone
|
multiple interactions
|
EXP
|
Erythrosine promotes the reaction [TRH protein results in increased expression of TSHB protein]
|
CTD |
PMID:2160137 |
|
NCBI chr 4:124,742,111...124,777,094
Ensembl chr 4:124,742,111...124,744,637
|
|
G
|
Tshb
|
thyroid stimulating hormone subunit beta
|
multiple interactions
|
EXP
|
Erythrosine promotes the reaction [TRH protein results in increased expression of TSHB protein]
|
CTD |
PMID:2160137 |
|
NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559
|
|
G
|
Ugt1a6
|
UDP glucuronosyltransferase family 1 member A6
|
decreases activity
|
ISO
|
Erythrosine results in decreased activity of UGT1A6 protein
|
CTD |
PMID:20041016 |
|
NCBI chr 9:96,195,018...96,256,264
Ensembl chr 9:88,713,184...88,808,465
|
|
G
|
Ugt2b7
|
UDP glucuronosyltransferase family 2 member B7
|
decreases activity
|
ISO
|
Erythrosine results in decreased activity of UGT2B7 protein
|
CTD |
PMID:20041016 |
|
NCBI chr14:21,251,535...21,274,451
Ensembl chr14:20,896,682...20,919,604
|
|
G
|
Vegfa
|
vascular endothelial growth factor A
|
increases expression
|
ISO
|
Erythrosine results in increased expression of VEGFA protein
|
CTD |
PMID:20025956 |
|
NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641
|
|
|
G
|
Akt1
|
AKT serine/threonine kinase 1
|
multiple interactions
|
EXP
|
GGTI-2133 inhibits the reaction [Smoke analog results in increased phosphorylation of AKT1 protein]
|
CTD |
PMID:19299917 |
|
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921
|
|
G
|
Mapk1
|
mitogen activated protein kinase 1
|
multiple interactions
|
EXP
|
GGTI-2133 inhibits the reaction [Smoke analog results in increased phosphorylation of MAPK1 protein]
|
CTD |
PMID:19299917 |
|
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616
|
|
G
|
Mapk3
|
mitogen activated protein kinase 3
|
multiple interactions
|
EXP
|
GGTI-2133 inhibits the reaction [Smoke analog results in increased phosphorylation of MAPK3 protein]
|
CTD |
PMID:19299917 |
|
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863
|
|
G
|
Mmp9
|
matrix metallopeptidase 9
|
multiple interactions
|
EXP
|
GGTI-2133 inhibits the reaction [Smoke analog results in increased expression of MMP9 mRNA]; GGTI-2133 inhibits the reaction [Smoke analog results in increased secretion of MMP9 protein]
|
CTD |
PMID:19299917 |
|
NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120
|
|
G
|
Rap1a
|
RAP1A, member of RAS oncogene family
|
decreases geranoylation
|
ISO
|
GGTI-2133 results in decreased geranoylation of RAP1A protein
|
CTD |
PMID:25578243 |
|
NCBI chr 2:195,896,967...195,974,851
Ensembl chr 2:193,208,635...193,286,501
|
|
|
G
|
Abcb11
|
ATP binding cassette subfamily B member 11
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of ABCB11 mRNA]
|
CTD |
PMID:28549656 |
|
NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:54,017,127...54,112,730
|
|
G
|
Abcb1a
|
ATP binding cassette subfamily B member 1A
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]; [Glycyrrhetinic Acid affects the activity of ABCB1 protein] which affects the susceptibility to Vinblastine; [Glycyrrhetinic Acid affects the activity of ABCB1 protein] which results in increased abundance of Daunorubicin; Glycyrrhetinic Acid inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin]; Glycyrrhetinic Acid inhibits the reaction [Verapamil results in increased activity of ABCB1 protein]
|
CTD |
PMID:16904803 PMID:18204840 PMID:24380838 |
|
NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:25,158,362...25,442,709
|
|
G
|
Abcb4
|
ATP binding cassette subfamily B member 4
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of ABCB4 mRNA]
|
CTD |
PMID:28549656 |
|
NCBI chr 4:26,106,895...26,164,440
Ensembl chr 4:25,151,953...25,209,202
|
|
G
|
Abcc1
|
ATP binding cassette subfamily C member 1
|
multiple interactions increases activity
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ABCC1 mRNA] Glycyrrhetinic Acid results in increased activity of ABCC1 protein [Glycyrrhetinic Acid affects the activity of ABCC1 protein] which affects the susceptibility to Doxorubicin; [Glycyrrhetinic Acid affects the activity of ABCC1 protein] which results in increased abundance of fluorexon
|
CTD |
PMID:18204840 PMID:28549656 |
|
NCBI chr10:1,022,041...1,162,431
Ensembl chr10:531,812...655,114
|
|
G
|
Abcc2
|
ATP binding cassette subfamily C member 2
|
multiple interactions
|
EXP
|
Glycyrrhetinic Acid inhibits the reaction [ABCC2 protein results in increased transport of estradiol-17 beta-glucuronide]
|
CTD |
PMID:18436619 |
|
NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:242,664,657...242,723,238
|
|
G
|
Abcc3
|
ATP binding cassette subfamily C member 3
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid affects the reaction [1-Naphthylisothiocyanate affects the expression of ABCC3 mRNA]
|
CTD |
PMID:28549656 |
|
NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,296,693...79,342,595
|
|
G
|
Abcg2
|
ATP binding cassette subfamily G member 2
|
multiple interactions
|
ISO
|
Glycyrrhetinic Acid inhibits the reaction [ABCG2 protein results in increased transport of estradiol-17 beta-glucuronide]
|
CTD |
PMID:18436619 |
|
NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:87,745,319...87,802,409
|
|
G
|
Abcg5
|
ATP binding cassette subfamily G member 5
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ABCG5 mRNA]
|
CTD |
PMID:28549656 |
|
NCBI chr 6:15,717,936...15,743,376
Ensembl chr 6:9,965,118...9,990,563
|
|
G
|
Acat2
|
acetyl-CoA acetyltransferase 2
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid affects the reaction [1-Naphthylisothiocyanate affects the expression of ACAT2 mRNA]
|
CTD |
PMID:28549656 |
|
NCBI chr 1:50,100,840...50,118,886
Ensembl chr 1:47,695,788...47,752,821
|
|
G
|
Acta2
|
actin alpha 2, smooth muscle
|
multiple interactions
|
EXP
|
18alpha-glycyrrhetinic acid inhibits the reaction [Monocrotaline results in increased expression of ACTA2 protein]
|
CTD |
PMID:31325423 |
|
NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:231,746,548...231,759,554
|
|
G
|
Akr1c1
|
aldo-keto reductase family 1, member C1
|
decreases activity
|
ISO
|
Glycyrrhetinic Acid results in decreased activity of AKR1C1 protein
|
CTD |
PMID:12604236 |
|
NCBI chr17:70,720,397...70,747,285
Ensembl chr17:65,810,475...65,837,326
|
|
G
|
Akr1c2
|
aldo-keto reductase family 1, member C2
|
decreases activity
|
ISO
|
Glycyrrhetinic Acid results in decreased activity of AKR1C2 protein
|
CTD |
PMID:12604236 |
|
NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
|
|
G
|
Akr1c3
|
aldo-keto reductase family 1, member C3
|
affects activity decreases activity
|
ISO
|
18alpha-glycyrrhetinic acid affects the activity of AKR1C3 protein Glycyrrhetinic Acid results in decreased activity of AKR1C3 protein
|
CTD |
PMID:11165023 PMID:12604236 |
|
NCBI chr17:71,020,884...71,037,779
Ensembl chr17:66,110,963...66,127,873
|
|
G
|
Alb
|
albumin
|
multiple interactions
|
ISO
|
ALB protein binds to and affects the transport of Glycyrrhetinic Acid
|
CTD |
PMID:8831264 |
|
NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,607,381...17,622,836
|
|
G
|
Alpl
|
alkaline phosphatase, biomineralization associated
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased activity of ALPL protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased expression of ALPL mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [Ethinyl Estradiol results in increased expression of ALPL protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [RUNX2 protein results in increased expression of ALPL mRNA]
|
CTD |
PMID:21910061 PMID:38244730 |
|
NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:149,951,409...150,006,446
|
|
G
|
Atf6
|
activating transcription factor 6
|
multiple interactions
|
EXP
|
18alpha-glycyrrhetinic acid inhibits the reaction [bisphenol A results in increased expression of ATF6 mRNA]
|
CTD |
PMID:35699857 |
|
NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
|
|
G
|
Atp8b1
|
ATPase phospholipid transporting 8B1
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of ATP8B1 mRNA]
|
CTD |
PMID:28549656 |
|
NCBI chr18:58,016,382...58,157,213
Ensembl chr18:58,018,268...58,157,396
|
|
G
|
Bax
|
BCL2 associated X, apoptosis regulator
|
multiple interactions decreases expression
|
EXP ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [bisphenol A results in increased expression of BAX]; 18alpha-glycyrrhetinic acid inhibits the reaction [Methotrexate results in increased expression of BAX protein]; Glycyrrhetinic Acid promotes the reaction [bisphenol A results in increased expression of BAX protein] Glycyrrhetinic Acid results in decreased expression of BAX protein 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in decreased expression of BAX protein]
|
CTD |
PMID:28414158 PMID:31325423 PMID:35699857 PMID:38348715 |
|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368
|
|
G
|
Bcl2
|
BCL2, apoptosis regulator
|
multiple interactions decreases expression
|
EXP ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [bisphenol A results in decreased expression of BCL2]; 18alpha-glycyrrhetinic acid inhibits the reaction [Methotrexate results in decreased expression of BCL2 protein]; Glycyrrhetinic Acid inhibits the reaction [bisphenol A results in decreased expression of BCL2 protein] Glycyrrhetinic Acid results in decreased expression of BCL2 protein 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of BCL2 protein]
|
CTD |
PMID:28414158 PMID:31325423 PMID:35699857 PMID:38348715 |
|
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
|
|
G
|
Bglap
|
bone gamma-carboxyglutamate protein
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased activity of BGLAP protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased expression of BGLAP mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [RUNX2 protein results in increased expression of BGLAP mRNA]
|
CTD |
PMID:21910061 |
|
NCBI chr 2:176,136,341...176,137,318
Ensembl chr 2:173,838,518...173,839,495
|
|
G
|
Bmp2
|
bone morphogenetic protein 2
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased activity of ALPL protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased activity of BGLAP protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased activity of RUNX2 protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased expression of ALPL mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased expression of BGLAP mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased expression of COL1A1 mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased expression of SP7 mRNA]
|
CTD |
PMID:21910061 |
|
NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:120,812,882...120,821,397
|
|
G
|
Casp3
|
caspase 3
|
multiple interactions
|
EXP
|
18alpha-glycyrrhetinic acid inhibits the reaction [bisphenol A results in increased expression of CASP3]
|
CTD |
PMID:35699857 |
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648
|
|
G
|
Cat
|
catalase
|
multiple interactions
|
ISO EXP
|
Glycyrrhetinic Acid inhibits the reaction [Carbon Tetrachloride results in decreased expression of CAT mRNA] Glycyrrhetinic Acid inhibits the reaction [bisphenol A results in decreased activity of CAT protein]
|
CTD |
PMID:23341968 PMID:38348715 |
|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478
|
|
G
|
Cdkn1b
|
cyclin-dependent kinase inhibitor 1B
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in decreased expression of CDKN1B protein]
|
CTD |
PMID:31325423 |
|
NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:167,760,181...167,764,982
|
|
G
|
Col1a1
|
collagen type I alpha 1 chain
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased expression of COL1A1 mRNA]
|
CTD |
PMID:21910061 |
|
NCBI chr10:80,380,458...80,397,461
Ensembl chr10:79,883,622...79,900,624
|
|
G
|
Csf2
|
colony stimulating factor 2
|
multiple interactions
|
ISO
|
Glycyrrhetinic Acid promotes the reaction [Hydrocortisone inhibits the reaction [IL1B protein results in increased secretion of CSF2 protein]]
|
CTD |
PMID:10460758 |
|
NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,386,945...38,389,199
|
|
G
|
Cxcr3
|
C-X-C motif chemokine receptor 3
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [Ethinyl Estradiol results in increased expression of CXCR3 mRNA]
|
CTD |
PMID:38244730 |
|
NCBI chr X:66,844,318...66,846,969
Ensembl chr X:66,844,318...66,846,969
|
|
G
|
Cycs
|
cytochrome c, somatic
|
decreases expression multiple interactions
|
EXP
|
Glycyrrhetinic Acid results in decreased expression of CYCS protein Glycyrrhetinic Acid inhibits the reaction [bisphenol A results in increased expression of CYCS protein]
|
CTD |
PMID:38348715 |
|
NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
|
|
G
|
Cyp1a2
|
cytochrome P450, family 1, subfamily a, polypeptide 2
|
multiple interactions
|
EXP
|
[brucine co-treated with Glycyrrhetinic Acid] results in decreased activity of CYP1A2 protein
|
CTD |
PMID:21800547 |
|
NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:58,075,367...58,082,312
|
|
G
|
Cyp2e1
|
cytochrome P450, family 2, subfamily e, polypeptide 1
|
multiple interactions
|
EXP
|
[brucine co-treated with Glycyrrhetinic Acid] results in decreased activity of CYP2E1 protein
|
CTD |
PMID:21800547 |
|
NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:195,840,058...195,864,023
|
|
G
|
Cyp7a1
|
cytochrome P450 family 7 subfamily A member 1
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of CYP7A1 mRNA]
|
CTD |
PMID:28549656 |
|
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
|
|
G
|
Eif2ak3
|
eukaryotic translation initiation factor 2 alpha kinase 3
|
multiple interactions
|
EXP
|
18alpha-glycyrrhetinic acid inhibits the reaction [bisphenol A results in increased expression of EIF2AK3 mRNA]
|
CTD |
PMID:35699857 |
|
NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:102,805,510...102,866,911
|
|
G
|
Ern1
|
endoplasmic reticulum to nucleus signaling 1
|
multiple interactions
|
ISO EXP
|
18alpha-glycyrrhetinic acid inhibits the reaction [Cadmium Chloride results in increased expression of ERN1 protein] 18alpha-glycyrrhetinic acid inhibits the reaction [bisphenol A results in increased expression of ERN1 mRNA]
|
CTD |
PMID:29444456 PMID:35699857 |
|
NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,330,654...91,421,029
|
|
G
|
Ggt1
|
gamma-glutamyltransferase 1
|
multiple interactions
|
EXP
|
18alpha-glycyrrhetinic acid inhibits the reaction [Methotrexate results in increased activity of GGT1 protein]
|
CTD |
PMID:28414158 |
|
NCBI chr20:13,074,141...13,103,551
Ensembl chr20:13,074,700...13,108,442
|
|
G
|
Got1
|
glutamic-oxaloacetic transaminase 1
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [Ethinyl Estradiol results in increased expression of GOT1 protein]
|
CTD |
PMID:38244730 |
|
NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:242,357,306...242,380,633
|
|
G
|
Gpt
|
glutamic--pyruvic transaminase
|
multiple interactions
|
ISO EXP
|
18alpha-glycyrrhetinic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased activity of GPT protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [Ethinyl Estradiol results in increased expression of GPT protein]; Glycyrrhetinic Acid inhibits the reaction [diosbulbin B results in increased activity of GPT protein] 18alpha-glycyrrhetinic acid inhibits the reaction [Methotrexate results in increased activity of GPT protein]
|
CTD |
PMID:28414158 PMID:28549656 PMID:36807597 PMID:38244730 |
|
NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:108,416,642...108,419,494
|
|
G
|
Gpx2
|
glutathione peroxidase 2
|
multiple interactions
|
ISO
|
Glycyrrhetinic Acid inhibits the reaction [Carbon Tetrachloride results in decreased expression of GPX2 mRNA]
|
CTD |
PMID:23341968 |
|
NCBI chr 6:101,226,745...101,230,033
Ensembl chr 6:95,493,589...95,496,877
|
|
G
|
Hmox1
|
heme oxygenase 1
|
multiple interactions
|
EXP
|
18alpha-glycyrrhetinic acid inhibits the reaction [Methotrexate results in decreased expression of HMOX1 mRNA]
|
CTD |
PMID:28414158 |
|
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079
|
|
G
|
Hras
|
HRas proto-oncogene, GTPase
|
decreases expression
|
ISO
|
Glycyrrhetinic Acid results in decreased expression of HRAS protein
|
CTD |
PMID:19958823 |
|
NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:196,296,263...196,300,615
|
|
G
|
Hsd11b1
|
hydroxysteroid 11-beta dehydrogenase 1
|
decreases activity
|
ISO
|
18alpha-glycyrrhetinic acid results in decreased activity of HSD11B1 protein
|
CTD |
PMID:24135201 |
|
NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
|
|
G
|
Hsd11b2
|
hydroxysteroid 11-beta dehydrogenase 2
|
decreases activity multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid results in decreased activity of HSD11B2 protein Glycyrrhetinic Acid inhibits the reaction [tributyltin results in increased activity of HSD11B2 protein]; Glycyrrhetinic Acid inhibits the reaction [triphenyltin chloride results in increased activity of HSD11B2 protein]
|
CTD |
PMID:24135201 PMID:31927052 |
|
NCBI chr19:50,307,569...50,312,812
Ensembl chr19:33,397,656...33,402,899
|
|
G
|
Hsd3b1
|
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
|
multiple interactions
|
ISO
|
[Glycyrrhetinic Acid co-treated with NADP] binds to HSD3B1 protein
|
CTD |
PMID:25526675 |
|
NCBI chr 2:188,858,574...188,864,694
Ensembl chr 2:186,169,863...186,175,999
|
|
G
|
Hspa5
|
heat shock protein family A (Hsp70) member 5
|
multiple interactions
|
EXP
|
18alpha-glycyrrhetinic acid inhibits the reaction [bisphenol A results in increased expression of HSPA5 mRNA]
|
CTD |
PMID:35699857 |
|
NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:18,055,405...18,059,891
|
|
G
|
Il1b
|
interleukin 1 beta
|
multiple interactions
|
EXP ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [Methotrexate results in increased expression of IL1B protein] Glycyrrhetinic Acid promotes the reaction [Hydrocortisone inhibits the reaction [IL1B protein results in increased secretion of CSF2 protein]] Glycyrrhetinic Acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B mRNA]
|
CTD |
PMID:10460758 PMID:23373965 PMID:28414158 |
|
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415
|
|
G
|
Il6
|
interleukin 6
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL6 protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; Glycyrrhetinic Acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 mRNA]
|
CTD |
PMID:21644799 PMID:23373965 PMID:24849676 |
|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178
|
|
G
|
Irak1
|
interleukin-1 receptor-associated kinase 1
|
multiple interactions
|
ISO
|
Glycyrrhetinic Acid inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] promotes the reaction [TRAF6 protein binds to IRAK1 protein]]
|
CTD |
PMID:28213090 |
|
NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521
|
|
G
|
Irak3
|
interleukin-1 receptor-associated kinase 3
|
increases expression multiple interactions
|
ISO
|
Glycyrrhetinic Acid results in increased expression of IRAK3 protein [Glycyrrhetinic Acid co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IRAK3 mRNA; IRAK3 protein promotes the reaction [Glycyrrhetinic Acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]]
|
CTD |
PMID:28213090 |
|
NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121
|
|
G
|
Ly96
|
lymphocyte antigen 96
|
multiple interactions
|
ISO
|
Glycyrrhetinic Acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of [TLR4 protein binds to LY96 protein]]
|
CTD |
PMID:28213090 |
|
NCBI chr 5:2,582,233...2,612,357
Ensembl chr 5:2,582,254...2,612,386
|
|
G
|
Map3k5
|
mitogen-activated protein kinase kinase kinase 5
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [Cadmium Chloride results in increased expression of MAP3K5 protein]
|
CTD |
PMID:29444456 |
|
NCBI chr 1:16,505,387...16,723,899
Ensembl chr 1:14,685,492...14,904,800
|
|
G
|
Mapk1
|
mitogen activated protein kinase 1
|
multiple interactions
|
ISO
|
Glycyrrhetinic Acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK1 protein]
|
CTD |
PMID:23373965 |
|
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616
|
|
G
|
Mapk3
|
mitogen activated protein kinase 3
|
multiple interactions
|
ISO
|
Glycyrrhetinic Acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK3 protein]
|
CTD |
PMID:23373965 |
|
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863
|
|
G
|
Mmp9
|
matrix metallopeptidase 9
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [TNF protein results in increased activity of MMP9 protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA]
|
CTD |
PMID:24613819 |
|
NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120
|
|
G
|
Mpo
|
myeloperoxidase
|
multiple interactions
|
ISO
|
Glycyrrhetinic Acid inhibits the reaction [diosbulbin B results in increased activity of MPO protein]
|
CTD |
PMID:36807597 |
|
NCBI chr10:73,092,124...73,102,057
Ensembl chr10:72,594,661...72,604,819
|
|
G
|
Mttp
|
microsomal triglyceride transfer protein
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of MTTP mRNA]
|
CTD |
PMID:28549656 |
|
NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
|
|
G
|
Nfe2l2
|
NFE2 like bZIP transcription factor 2
|
multiple interactions increases expression
|
EXP ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [Methotrexate results in decreased expression of NFE2L2 mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [Methotrexate results in decreased expression of NFE2L2 protein] [Glycyrrhetinic Acid results in increased expression of NFE2L2] which results in decreased susceptibility to Carbon Tetrachloride; Glycyrrhetinic Acid inhibits the reaction [Carbon Tetrachloride affects the localization of NFE2L2 protein]
|
CTD |
PMID:23341968 PMID:28414158 |
|
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737
|
|
G
|
Nfkb1
|
nuclear factor kappa B subunit 1
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [TNF protein results in decreased expression of NFKB1 protein]
|
CTD |
PMID:24613819 |
|
NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:224,016,214...224,110,404
|
|
G
|
Nfkbia
|
NFKB inhibitor alpha
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased degradation of NFKBIA protein] Glycyrrhetinic Acid inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased phosphorylation of NFKBIA protein]; Glycyrrhetinic Acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of and affects the localization of NFKBIA protein]
|
CTD |
PMID:23373965 PMID:24613819 PMID:28213090 |
|
NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941
|
|
G
|
Nos2
|
nitric oxide synthase 2
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 protein]; Glycyrrhetinic Acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 protein]
|
CTD |
PMID:21644799 PMID:23373965 |
|
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:63,815,308...63,851,210
|
|
G
|
Npc1l1
|
NPC1 like intracellular cholesterol transporter 1
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of NPC1L1 mRNA]
|
CTD |
PMID:28549656 |
|
NCBI chr14:81,071,448...81,091,113
Ensembl chr14:81,071,451...81,091,113
|
|
G
|
Pdgfb
|
platelet derived growth factor subunit B
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in decreased expression of BAX protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in decreased expression of CDKN1B protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of BCL2 protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of RHOA mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of RHOA protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of ROCK1 mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of ROCK1 protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of ROCK2 mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of ROCK2 protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of PPP1R12A protein]
|
CTD |
PMID:31325423 |
|
NCBI chr 7:113,419,882...113,438,343
Ensembl chr 7:111,540,345...111,557,984
|
|
G
|
Pik3cd
|
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
|
decreases activity
|
ISO
|
18alpha-glycyrrhetinic acid results in decreased activity of PIK3CD protein
|
CTD |
PMID:21644799 |
|
NCBI chr 5:165,377,994...165,426,620
Ensembl chr 5:160,094,952...160,120,930
|
|
G
|
Pik3cg
|
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
|
decreases activity
|
ISO
|
18alpha-glycyrrhetinic acid results in decreased activity of PIK3CG protein
|
CTD |
PMID:21644799 |
|
NCBI chr 6:54,494,247...54,529,563
Ensembl chr 6:48,766,864...48,802,043
|
|
G
|
Pparg
|
peroxisome proliferator-activated receptor gamma
|
multiple interactions
|
EXP
|
18alpha-glycyrrhetinic acid inhibits the reaction [Methotrexate results in decreased expression of PPARG mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [Methotrexate results in decreased expression of PPARG protein]
|
CTD |
PMID:28414158 |
|
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:148,423,194...148,548,468
|
|
G
|
Ppp1r12a
|
protein phosphatase 1, regulatory subunit 12A
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of PPP1R12A protein]
|
CTD |
PMID:31325423 |
|
NCBI chr 7:45,368,922...45,480,158
Ensembl chr 7:43,482,803...43,593,425
|
|
G
|
Ptgs2
|
prostaglandin-endoperoxide synthase 2
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 protein]
|
CTD |
PMID:21644799 |
|
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188
|
|
G
|
Rela
|
RELA proto-oncogene, NF-kB subunit
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [TNF protein results in decreased expression of RELA protein] Glycyrrhetinic Acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 affects the localization of RELA protein]
|
CTD |
PMID:23373965 PMID:24613819 |
|
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484
|
|
G
|
Ren
|
renin
|
decreases activity
|
ISO
|
Glycyrrhetinic Acid results in decreased activity of REN protein
|
CTD |
PMID:20460744 |
|
NCBI chr13:47,348,312...47,359,539
Ensembl chr13:44,796,091...44,807,489
|
|
G
|
Rhoa
|
ras homolog family member A
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of RHOA mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of RHOA protein]
|
CTD |
PMID:31325423 |
|
NCBI chr 8:117,870,548...117,904,303
Ensembl chr 8:108,991,954...109,025,746
|
|
G
|
Rock1
|
Rho-associated coiled-coil containing protein kinase 1
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of ROCK1 mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of ROCK1 protein]
|
CTD |
PMID:31325423 |
|
NCBI chr18:1,387,360...1,509,218
Ensembl chr18:1,115,905...1,235,571
|
|
G
|
Rock2
|
Rho-associated coiled-coil containing protein kinase 2
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of ROCK2 mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of ROCK2 protein]
|
CTD |
PMID:31325423 |
|
NCBI chr 6:45,407,823...45,502,773
Ensembl chr 6:39,679,082...39,774,031
|
|
G
|
Rorc
|
RAR-related orphan receptor C
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [Ethinyl Estradiol results in increased expression of RORC mRNA]
|
CTD |
PMID:38244730 |
|
NCBI chr 2:184,698,779...184,723,942
Ensembl chr 2:182,009,286...182,034,907
|
|
G
|
Runx2
|
RUNX family transcription factor 2
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased activity of RUNX2 protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [RUNX2 protein results in increased expression of ALPL mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [RUNX2 protein results in increased expression of BGLAP mRNA]
|
CTD |
PMID:21910061 |
|
NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:16,167,482...16,492,167
|
|
G
|
Slc51b
|
SLC51 subunit beta
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of SLC51B mRNA]
|
CTD |
PMID:28549656 |
|
NCBI chr 8:74,827,047...74,835,109
Ensembl chr 8:65,931,890...65,940,145
|
|
G
|
Slco1a4
|
solute carrier organic anion transporter family, member 1a4
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of SLCO1A4 mRNA]
|
CTD |
PMID:28549656 |
|
NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573
|
|
G
|
Sod3
|
superoxide dismutase 3
|
multiple interactions
|
ISO
|
Glycyrrhetinic Acid inhibits the reaction [Carbon Tetrachloride results in decreased expression of SOD3 mRNA]
|
CTD |
PMID:23341968 |
|
NCBI chr14:62,822,865...62,828,602
Ensembl chr14:58,609,958...58,615,990
|
|
G
|
Sp7
|
Sp7 transcription factor
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased expression of SP7 mRNA]
|
CTD |
PMID:21910061 |
|
NCBI chr 7:135,363,193...135,373,376
Ensembl chr 7:133,484,609...133,494,847
|
|
G
|
Tlr4
|
toll-like receptor 4
|
multiple interactions
|
ISO
|
Glycyrrhetinic Acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of [TLR4 protein binds to LY96 protein]]
|
CTD |
PMID:28213090 |
|
NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628
|
|
G
|
Tnf
|
tumor necrosis factor
|
multiple interactions
|
ISO EXP
|
18alpha-glycyrrhetinic acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]; Glycyrrhetinic Acid inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased expression of and results in increased secretion of TNF protein]; Glycyrrhetinic Acid inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased expression of TNF mRNA]; Glycyrrhetinic Acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]; IRAK3 protein promotes the reaction [Glycyrrhetinic Acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]] 18alpha-glycyrrhetinic acid inhibits the reaction [Methotrexate results in increased expression of TNF protein] 18alpha-glycyrrhetinic acid inhibits the reaction [TNF protein results in decreased expression of NFKB1 protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [TNF protein results in decreased expression of RELA protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [TNF protein results in increased activity of MMP9 protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of VEGFA protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [TNF protein results in increased expression of VEGFA mRNA]; 18alpha-glycyrrhetinic acid inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased degradation of NFKBIA protein]
|
CTD |
PMID:21644799 PMID:24613819 PMID:28213090 PMID:28414158 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
|
|
G
|
Tp53
|
tumor protein p53
|
decreases expression
|
EXP
|
Glycyrrhetinic Acid results in decreased expression of TP53 protein
|
CTD |
PMID:38348715 |
|
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524
|
|
G
|
Traf6
|
TNF receptor associated factor 6
|
multiple interactions
|
ISO
|
Glycyrrhetinic Acid inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] promotes the reaction [TRAF6 protein binds to IRAK1 protein]]
|
CTD |
PMID:28213090 |
|
NCBI chr 3:108,418,537...108,443,330
Ensembl chr 3:87,963,514...87,983,507
|
|
G
|
Vegfa
|
vascular endothelial growth factor A
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of VEGFA protein]; 18alpha-glycyrrhetinic acid inhibits the reaction [TNF protein results in increased expression of VEGFA mRNA]
|
CTD |
PMID:24613819 |
|
NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641
|
|
G
|
Xbp1
|
X-box binding protein 1
|
multiple interactions
|
ISO
|
18alpha-glycyrrhetinic acid inhibits the reaction [Cadmium Chloride results in increased expression of XBP1 protein alternative form]
|
CTD |
PMID:29444456 |
|
NCBI chr14:84,604,623...84,609,707
Ensembl chr14:80,390,643...80,395,693
|
|
|
G
|
Aanat
|
aralkylamine N-acetyltransferase
|
multiple interactions
|
EXP
|
Ketorolac Tromethamine results in decreased localization of and results in decreased activity of AANAT protein
|
CTD |
PMID:37348669 |
|
NCBI chr10:101,827,072...101,831,805
Ensembl chr10:101,827,301...101,831,801
|
|
G
|
Cat
|
catalase
|
multiple interactions increases activity
|
EXP
|
Melatonin inhibits the reaction [Ketorolac Tromethamine results in increased activity of CAT protein]
|
CTD |
PMID:37348669 |
|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478
|
|
G
|
Ereg
|
epiregulin
|
increases expression
|
ISO
|
Ketorolac Tromethamine results in increased expression of EREG mRNA
|
CTD |
PMID:32816093 |
|
NCBI chr14:17,311,485...17,325,260
Ensembl chr14:17,027,287...17,041,062
|
|
G
|
Gpx1
|
glutathione peroxidase 1
|
decreases activity
|
EXP
|
Ketorolac Tromethamine results in decreased activity of GPX1 protein
|
CTD |
PMID:37348669 |
|
NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024
|
|
G
|
Gsr
|
glutathione-disulfide reductase
|
increases activity
|
EXP
|
Ketorolac Tromethamine results in increased activity of GSR protein
|
CTD |
PMID:37348669 |
|
NCBI chr16:65,185,574...65,228,742
Ensembl chr16:58,482,505...58,525,661
|
|
G
|
Il24
|
interleukin 24
|
increases expression
|
ISO
|
Ketorolac Tromethamine results in increased expression of IL24 mRNA
|
CTD |
PMID:32816093 |
|
NCBI chr13:44,905,362...44,910,760
Ensembl chr13:42,353,090...42,358,487
|
|
G
|
Maoa
|
monoamine oxidase A
|
multiple interactions increases activity
|
EXP
|
Melatonin inhibits the reaction [Ketorolac Tromethamine results in increased activity of MAOA protein]
|
CTD |
PMID:37348669 |
|
NCBI chr X:8,615,239...8,681,372
Ensembl chr X:6,030,795...6,099,593
|
|
G
|
Mtnr1a
|
melatonin receptor 1A
|
increases localization
|
EXP
|
Ketorolac Tromethamine results in increased localization of MTNR1A protein
|
CTD |
PMID:37348669 |
|
NCBI chr16:47,144,461...47,163,919
Ensembl chr16:47,144,461...47,163,919
|
|
G
|
Ptgs2
|
prostaglandin-endoperoxide synthase 2
|
increases expression
|
ISO
|
Ketorolac Tromethamine results in increased expression of PTGS2 mRNA
|
CTD |
PMID:32816093 |
|
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188
|
|
G
|
Slpi
|
secretory leukocyte peptidase inhibitor
|
increases expression
|
ISO
|
Ketorolac Tromethamine results in increased expression of SLPI mRNA
|
CTD |
PMID:32816093 |
|
NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453
|
|
G
|
Sod1
|
superoxide dismutase 1
|
decreases activity
|
EXP
|
Ketorolac Tromethamine results in decreased activity of SOD1 protein
|
CTD |
PMID:37348669 |
|
NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249
|
|
G
|
Sod2
|
superoxide dismutase 2
|
decreases activity
|
EXP
|
Ketorolac Tromethamine results in decreased activity of SOD2 protein
|
CTD |
PMID:37348669 |
|
NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189
|
|
|
G
|
App
|
amyloid beta precursor protein
|
decreases expression
|
ISO
|
lead tetraacetate results in decreased expression of APP mRNA
|
CTD |
PMID:20865013 |
|
NCBI chr11:37,506,207...37,724,351
Ensembl chr11:24,019,778...24,236,561
|
|
G
|
Mapt
|
microtubule-associated protein tau
|
decreases expression
|
ISO
|
lead tetraacetate results in decreased expression of MAPT mRNA
|
CTD |
PMID:20865013 |
|
NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,138,627...89,236,129
|
|
G
|
Nrxn1
|
neurexin 1
|
decreases expression
|
ISO
|
lead tetraacetate results in decreased expression of NRXN1 mRNA
|
CTD |
PMID:20865013 |
|
NCBI chr 6:8,931,360...10,077,381
Ensembl chr 6:3,177,897...4,322,710
|
|
G
|
Prnp
|
prion protein
|
decreases expression
|
ISO
|
lead tetraacetate results in decreased expression of PRNP mRNA
|
CTD |
PMID:20865013 |
|
NCBI chr 3:139,639,076...139,654,420
Ensembl chr 3:119,177,485...119,203,937
|
|
G
|
Syp
|
synaptophysin
|
decreases expression
|
ISO
|
lead tetraacetate results in decreased expression of SYP mRNA
|
CTD |
PMID:20865013 |
|
NCBI chr X:17,521,348...17,536,449
Ensembl chr X:14,849,444...14,864,745
|
|
G
|
Tubb3
|
tubulin, beta 3 class III
|
decreases expression
|
ISO
|
lead tetraacetate results in decreased expression of TUBB3 mRNA
|
CTD |
PMID:20865013 |
|
NCBI chr19:68,365,687...68,374,741
Ensembl chr19:51,457,184...51,466,243
|
|
|
G
|
Birc2
|
baculoviral IAP repeat-containing 2
|
increases degradation
|
ISO
|
Lobaplatin increases degradation of BIRC2 protein in human nasopharyngeal carcinoma cells
|
RGD |
PMID:32413426 |
RGD:155226873 |
NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
|
|
G
|
Birc3
|
baculoviral IAP repeat-containing 3
|
increases degradation
|
ISO
|
Lobaplatin increases degradation of BIRC3 protein in human nasopharyngeal carcinoma cells
|
RGD |
PMID:32413426 |
RGD:155226873 |
NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
|
|
|
G
|
Bax
|
BCL2 associated X, apoptosis regulator
|
increases expression
|
ISO
|
Diatrizoate Meglumine results in increased expression of BAX protein
|
CTD |
PMID:17173243 |
|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368
|
|
G
|
Bcl2
|
BCL2, apoptosis regulator
|
increases expression decreases expression multiple interactions
|
ISO EXP
|
Diatrizoate Meglumine results in increased expression of BCL2 protein Diatrizoate Meglumine results in decreased expression of BCL2 mRNA Lansoprazole inhibits the reaction [Diatrizoate Meglumine results in decreased expression of BCL2 mRNA]
|
CTD |
PMID:17173243 PMID:28412091 |
|
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
|
|
G
|
Casp12
|
caspase 12
|
increases cleavage
|
EXP
|
Diatrizoate Meglumine results in increased cleavage of CASP12 protein
|
CTD |
PMID:20071420 |
|
NCBI chr 8:10,927,188...10,954,442
Ensembl chr 8:2,642,434...2,674,037
|
|
G
|
Casp3
|
caspase 3
|
increases activity increases expression multiple interactions
|
ISO EXP
|
Diatrizoate Meglumine results in increased activity of CASP3 protein Diatrizoate Meglumine results in increased expression of CASP3 mRNA [Diatrizoate Meglumine co-treated with Gentamicins] results in increased cleavage of CASP3 protein; [sulforaphane co-treated with Diatrizoate Meglumine] results in increased activity of CASP3 protein; CTF1 protein inhibits the reaction [[Diatrizoate Meglumine co-treated with Gentamicins] results in increased cleavage of CASP3 protein]; Lansoprazole inhibits the reaction [Diatrizoate Meglumine results in increased expression of CASP3 mRNA]; NFE2L2 protein affects the reaction [[sulforaphane co-treated with Diatrizoate Meglumine] results in increased activity of CASP3 protein]
|
CTD |
PMID:17173243 PMID:23335628 PMID:28412091 PMID:31173751 |
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648
|
|
G
|
Ctf1
|
cardiotrophin 1
|
multiple interactions
|
EXP
|
CTF1 protein inhibits the reaction [[Diatrizoate Meglumine co-treated with Gentamicins] results in increased cleavage of CASP3 protein]; CTF1 protein inhibits the reaction [[Diatrizoate Meglumine co-treated with Gentamicins] results in increased expression of HAVCR1 protein]; CTF1 protein inhibits the reaction [[Diatrizoate Meglumine co-treated with Gentamicins] results in increased expression of SERPINE1 protein]
|
CTD |
PMID:23335628 |
|
NCBI chr 1:191,758,512...191,771,259
Ensembl chr 1:182,328,090...182,333,335
|
|
G
|
Eif2a
|
eukaryotic translation initiation factor 2A
|
increases phosphorylation
|
EXP
|
Diatrizoate Meglumine results in increased phosphorylation of EIF2A protein
|
CTD |
PMID:20071420 |
|
NCBI chr 2:144,911,247...144,944,705
Ensembl chr 2:142,761,416...142,795,068
|
|
G
|
Eif2ak3
|
eukaryotic translation initiation factor 2 alpha kinase 3
|
increases phosphorylation
|
EXP
|
Diatrizoate Meglumine results in increased phosphorylation of EIF2AK3 protein
|
CTD |
PMID:20071420 |
|
NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:102,805,510...102,866,911
|
|
G
|
Gsta2
|
glutathione S-transferase alpha 2
|
increases expression
|
EXP
|
Diatrizoate Meglumine results in increased expression of GSTA2 mRNA
|
CTD |
PMID:28412091 |
|
NCBI chr 8:88,064,829...88,077,168
Ensembl chr 8:79,184,322...79,196,798
|
|
G
|
Havcr1
|
hepatitis A virus cellular receptor 1
|
multiple interactions
|
EXP
|
[Diatrizoate Meglumine co-treated with Gentamicins] results in increased expression of HAVCR1 protein; CTF1 protein inhibits the reaction [[Diatrizoate Meglumine co-treated with Gentamicins] results in increased expression of HAVCR1 protein]
|
CTD |
PMID:23335628 |
|
NCBI chr10:31,619,914...31,652,955
Ensembl chr10:31,119,088...31,151,698
|
|
G
|
Hmox1
|
heme oxygenase 1
|
increases expression decreases expression multiple interactions
|
EXP
|
Diatrizoate Meglumine results in increased expression of HMOX1 mRNA Diatrizoate Meglumine results in decreased expression of HMOX1 protein Lansoprazole inhibits the reaction [Diatrizoate Meglumine results in increased expression of HMOX1 mRNA]
|
CTD |
PMID:28412091 PMID:31173751 |
|
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079
|
|
G
|
Hsp90b1
|
heat shock protein 90 beta family member 1
|
increases expression
|
EXP
|
Diatrizoate Meglumine results in increased expression of HSP90B1 protein
|
CTD |
PMID:20071420 |
|
NCBI chr 7:22,997,962...23,012,293
Ensembl chr 7:21,110,457...21,124,788
|
|
G
|
Hspa5
|
heat shock protein family A (Hsp70) member 5
|
increases expression
|
EXP
|
Diatrizoate Meglumine results in increased expression of HSPA5 protein
|
CTD |
PMID:20071420 |
|
NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:18,055,405...18,059,891
|
|
G
|
Il6
|
interleukin 6
|
multiple interactions increases expression
|
EXP
|
Lansoprazole inhibits the reaction [Diatrizoate Meglumine results in increased expression of IL6 mRNA]; NFE2L2 protein affects the reaction [sulforaphane inhibits the reaction [Diatrizoate Meglumine results in increased expression of IL6 protein]]; sulforaphane inhibits the reaction [Diatrizoate Meglumine results in increased expression of IL6 protein] Diatrizoate Meglumine results in increased expression of IL6 mRNA; Diatrizoate Meglumine results in increased expression of IL6 protein
|
CTD |
PMID:28412091 PMID:31173751 |
|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178
|
|
G
|
Nfe2l2
|
NFE2 like bZIP transcription factor 2
|
multiple interactions decreases expression increases expression
|
EXP
|
Lansoprazole inhibits the reaction [Diatrizoate Meglumine results in increased expression of NFE2L2 mRNA]; NFE2L2 protein affects the reaction [[sulforaphane co-treated with Diatrizoate Meglumine] results in increased activity of CASP3 protein]; NFE2L2 protein affects the reaction [sulforaphane inhibits the reaction [Diatrizoate Meglumine results in increased expression of IL6 protein]] Diatrizoate Meglumine results in decreased expression of NFE2L2 protein
|
CTD |
PMID:28412091 PMID:31173751 |
|
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737
|
|
G
|
Serpine1
|
serpin family E member 1
|
multiple interactions
|
EXP
|
[Diatrizoate Meglumine co-treated with Gentamicins] results in increased expression of SERPINE1 protein; CTF1 protein inhibits the reaction [[Diatrizoate Meglumine co-treated with Gentamicins] results in increased expression of SERPINE1 protein]
|
CTD |
PMID:23335628 |
|
NCBI chr12:25,237,977...25,248,356
Ensembl chr12:19,601,272...19,611,657
|
|
G
|
Tp53
|
tumor protein p53
|
increases expression multiple interactions
|
EXP
|
Diatrizoate Meglumine results in increased expression of TP53 mRNA Lansoprazole inhibits the reaction [Diatrizoate Meglumine results in increased expression of TP53 mRNA]
|
CTD |
PMID:28412091 |
|
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524
|
|
|
G
|
Car2
|
carbonic anhydrase 2
|
decreases activity
|
ISO
|
Merbromin results in decreased activity of CA2 protein
|
CTD |
PMID:16858005 |
|
NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:86,741,626...86,756,818
|
|
G
|
Gstp1
|
glutathione S-transferase pi 1
|
multiple interactions
|
ISO
|
Merbromin inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate]
|
CTD |
PMID:23769903 |
|
NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226
|
|
|
G
|
Ace
|
angiotensin I converting enzyme
|
multiple interactions
|
ISO EXP
|
oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of ACE mRNA]]; oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of ACE protein]]; trigonelline affects the reaction [INS2 protein affects the expression of ACE mRNA]; trigonelline affects the reaction [INS2 protein affects the expression of ACE protein] oltipraz inhibits the reaction [trigonelline inhibits the reaction [Glucose results in increased expression of ACE mRNA]]; trigonelline inhibits the reaction [Glucose results in increased expression of ACE mRNA]
|
CTD |
PMID:29211853 |
|
NCBI chr10:91,410,129...91,430,246
Ensembl chr10:90,910,316...90,931,131
|
|
G
|
Ace2
|
angiotensin converting enzyme 2
|
multiple interactions
|
ISO EXP
|
oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of ACE2 mRNA]]; oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of ACE2 protein]]; trigonelline affects the reaction [INS2 protein affects the expression of ACE2 mRNA]; trigonelline affects the reaction [INS2 protein affects the expression of ACE2 protein] oltipraz inhibits the reaction [trigonelline inhibits the reaction [Glucose results in decreased expression of ACE2 mRNA]]; trigonelline inhibits the reaction [Glucose results in decreased expression of ACE2 mRNA]
|
CTD |
PMID:29211853 |
|
NCBI chr X:33,925,458...33,972,851
Ensembl chr X:30,293,589...30,340,977
|
|
G
|
Agt
|
angiotensinogen
|
multiple interactions
|
ISO EXP
|
oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of AGT mRNA]]; oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of AGT protein]]; trigonelline affects the reaction [INS2 protein affects the expression of AGT mRNA]; trigonelline affects the reaction [INS2 protein affects the expression of AGT protein] oltipraz inhibits the reaction [trigonelline inhibits the reaction [Glucose results in increased expression of AGT mRNA]]; trigonelline inhibits the reaction [Glucose results in increased expression of AGT mRNA]
|
CTD |
PMID:29211853 |
|
NCBI chr19:69,426,540...69,447,017
Ensembl chr19:52,529,185...52,540,977
|
|
G
|
Atg7
|
autophagy related 7
|
multiple interactions
|
ISO
|
trigonelline inhibits the reaction [Palmitic Acid results in decreased expression of ATG7 protein] ATG7 protein affects the reaction [trigonelline inhibits the reaction [Palmitic Acid results in increased expression of PPARG protein]]; ATG7 protein affects the reaction [trigonelline inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein]]; trigonelline inhibits the reaction [Palmitic Acid results in decreased expression of ATG7 protein]
|
CTD |
PMID:30208301 |
|
NCBI chr 4:149,390,000...149,597,534
Ensembl chr 4:147,718,752...147,925,593
|
|
G
|
Bax
|
BCL2 associated X, apoptosis regulator
|
multiple interactions
|
EXP ISO
|
trigonelline inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BAX protein] [trigonelline co-treated with Cisplatin] results in increased expression of BAX protein; [trigonelline co-treated with Etoposide] results in increased expression of BAX protein
|
CTD |
PMID:31935362 PMID:33148531 |
|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368
|
|
G
|
Bcl2
|
BCL2, apoptosis regulator
|
multiple interactions
|
EXP ISO
|
trigonelline inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of BCL2 protein] [trigonelline co-treated with Cisplatin] results in decreased expression of BCL2 protein; [trigonelline co-treated with Etoposide] results in decreased expression of BCL2 protein
|
CTD |
PMID:31935362 PMID:33148531 |
|
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
|
|
G
|
Becn1
|
beclin 1
|
multiple interactions
|
ISO
|
trigonelline inhibits the reaction [Palmitic Acid results in decreased expression of BECN1 protein] trigonelline inhibits the reaction [[Cholesterol, Dietary co-treated with Dietary Fats] results in decreased expression of BECN1 protein]; trigonelline inhibits the reaction [Palmitic Acid results in decreased expression of BECN1 protein]
|
CTD |
PMID:30208301 |
|
NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,231,388...86,246,742
|
|
G
|
Casp3
|
caspase 3
|
increases activity multiple interactions
|
ISO EXP
|
trigonelline results in increased activity of CASP3 protein [trigonelline co-treated with Cisplatin] results in increased cleavage of CASP3 protein; [trigonelline co-treated with Etoposide] results in increased cleavage of CASP3 protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [trigonelline inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]]; trigonelline inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]
|
CTD |
PMID:26593444 PMID:31935362 PMID:33148531 |
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648
|
|
G
|
Cd36
|
CD36 molecule
|
multiple interactions
|
ISO
|
trigonelline inhibits the reaction [[Cholesterol, Dietary co-treated with Dietary Fats] results in increased expression of CD36 protein]; trigonelline inhibits the reaction [Palmitic Acid results in increased expression of CD36 protein]
|
CTD |
PMID:30208301 |
|
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
|
|
G
|
Ddit3
|
DNA-damage inducible transcript 3
|
multiple interactions
|
ISO
|
[trigonelline co-treated with ferric citrate] results in increased expression of DDIT3 mRNA
|
CTD |
PMID:29959986 |
|
NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:63,116,380...63,121,201
|
|
G
|
Egf
|
epidermal growth factor
|
multiple interactions
|
ISO
|
trigonelline inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; trigonelline inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; trigonelline inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; trigonelline inhibits the reaction [EGF protein results in increased phosphorylation of NFE2L2 protein]
|
CTD |
PMID:33148531 |
|
NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:218,219,415...218,302,064
|
|
G
|
Egfr
|
epidermal growth factor receptor
|
multiple interactions decreases phosphorylation
|
ISO
|
trigonelline inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] trigonelline results in decreased phosphorylation of EGFR protein
|
CTD |
PMID:33148531 |
|
NCBI chr14:95,378,626...95,551,358
Ensembl chr14:91,177,067...91,344,382
|
|
G
|
Eif2s1
|
eukaryotic translation initiation factor 2 subunit alpha
|
multiple interactions
|
ISO
|
trigonelline inhibits the reaction [Palmitic Acid results in increased phosphorylation of EIF2S1 protein]
|
CTD |
PMID:30208301 |
|
NCBI chr 6:103,405,880...103,430,549
Ensembl chr 6:97,672,766...97,706,225
|
|
G
|
Fth1
|
ferritin heavy chain 1
|
multiple interactions
|
ISO
|
[trigonelline co-treated with ferric citrate] results in increased expression of FTH1 mRNA
|
CTD |
PMID:29959986 |
|
NCBI chr 1:216,052,037...216,054,325
Ensembl chr 1:206,627,103...206,725,424
|
|
G
|
Ftl1
|
ferritin light chain 1
|
multiple interactions
|
ISO
|
[trigonelline co-treated with ferric citrate] results in increased expression of FTL mRNA
|
CTD |
PMID:29959986 |
|
NCBI chr 1:105,072,858...105,074,705
Ensembl chr 1:95,936,387...95,939,725 Ensembl chr10:95,936,387...95,939,725 Ensembl chr 2:95,936,387...95,939,725
|
|
G
|
Gclc
|
glutamate-cysteine ligase, catalytic subunit
|
multiple interactions
|
ISO
|
trigonelline inhibits the reaction [Pyocyanine results in increased expression of GCLC mRNA]
|
CTD |
PMID:24015256 |
|
NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:78,630,127...78,668,544
|
|
G
|
Hexb
|
hexosaminidase subunit beta
|
multiple interactions
|
ISO
|
trigonelline inhibits the reaction [iodixanol results in increased secretion of HEXB protein]
|
CTD |
PMID:34774977 |
|
NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
|
|
G
|
Hmox1
|
heme oxygenase 1
|
decreases expression
|
ISO
|
trigonelline results in decreased expression of HMOX1 mRNA; trigonelline results in decreased expression of HMOX1 protein
|
CTD |
PMID:33148531 |
|
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079
|
|
G
|
Hspa5
|
heat shock protein family A (Hsp70) member 5
|
multiple interactions
|
ISO
|
trigonelline inhibits the reaction [Palmitic Acid results in increased expression of HSPA5 protein]
|
CTD |
PMID:30208301 |
|
NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:18,055,405...18,059,891
|
|
G
|
Il1b
|
interleukin 1 beta
|
multiple interactions
|
EXP
|
trigonelline inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of IL1B protein]
|
CTD |
PMID:31935362 |
|
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415
|
|
G
|
Il6
|
interleukin 6
|
multiple interactions
|
EXP
|
trigonelline inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of IL6 protein]
|
CTD |
PMID:31935362 |
|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178
|
|
G
|
Ins1
|
insulin 1
|
multiple interactions
|
ISO
|
trigonelline inhibits the reaction [[Cholesterol, Dietary co-treated with Dietary Fats] results in increased expression of INS1 protein]
|
CTD |
PMID:30208301 |
|
NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:251,244,973...251,245,536
|
|
G
|
Ins2
|
insulin 2
|
multiple interactions
|
ISO
|
oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of ACE mRNA]]; oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of ACE protein]]; oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of ACE2 mRNA]]; oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of ACE2 protein]]; oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of AGT mRNA]]; oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of AGT protein]]; oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of MAS1 mRNA]]; oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of MAS1 protein]]; oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of NFE2L2 protein]]; oltipraz inhibits the reaction [trigonelline affects the reaction [INS2 protein affects the expression of NFE2L2 mRNA]]; trigonelline affects the reaction [INS2 protein affects the expression of ACE mRNA]; trigonelline affects the reaction [INS2 protein affects the expression of ACE protein]; trigonelline affects the reaction [INS2 protein affects the expression of ACE2 mRNA]; trigonelline affects the reaction [INS2 protein affects the expression of ACE2 protein]; trigonelline affects the reaction [INS2 protein affects the expression of AGT mRNA]; trigonelline affects the reaction [INS2 protein affects the expression of AGT protein]; trigonelline affects the reaction [INS2 protein affects the expression of MAS1 mRNA]; trigonelline affects the reaction [INS2 protein affects the expression of MAS1 protein]; trigonelline affects the reaction [INS2 protein affects the expression of NFE2L2 mRNA]; trigonelline affects the reaction [INS2 protein affects the expression of NFE2L2 protein]; trigonelline inhibits the reaction [INS2 protein affects the abundance of angiotensin I (1-7)]
|
CTD |
PMID:29211853 |
|
NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:197,843,281...197,864,775
|
|
G
|
Keap1
|
Kelch-like ECH-associated protein 1
|
multiple interactions
|
ISO
|
[trigonelline co-treated with ferric citrate] results in decreased expression of KEAP1 mRNA
|
CTD |
PMID:29959986 |
|
NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:19,768,375...19,777,862
|
|
G
|
Lepr
|
leptin receptor
|
affects abundance
|
ISO
|
LEPR affects the abundance of trigonelline
|
CTD |
PMID:20567778 |
|
NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:116,289,823...116,475,908
|
|
G
|
Mapk1
|
mitogen activated protein kinase 1
|
multiple interactions decreases phosphorylation
|
ISO
|
trigonelline inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein] trigonelline results in decreased phosphorylation of MAPK1 protein
|
CTD |
PMID:33148531 |
|
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616
|
|
G
|
Mapk3
|
mitogen activated protein kinase 3
|
multiple interactions decreases phosphorylation
|
ISO
|
trigonelline inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein] trigonelline results in decreased phosphorylation of MAPK3 protein
|
CTD |
PMID:33148531 |
|
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863
|
|
G
|
Mas1
|
MAS1 proto-oncogene, G protein-coupled receptor
|
multiple interactions
|
EXP ISO
|
oltipraz inhibits the reaction [trigonelline inhibits the reaction [Glucose results in decreased expression of MAS1 mRNA]]; trigonelline inhibits the reaction [Glucose results in decreased expression of MAS1 mRNA] oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of MAS1 mRNA]]; oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of MAS1 protein]]; trigonelline affects the reaction [INS2 protein affects the expression of MAS1 mRNA]; trigonelline affects the reaction [INS2 protein affects the expression of MAS1 protein]
|
CTD |
PMID:29211853 |
|
NCBI chr 1:47,879,956...47,911,500
Ensembl chr 1:47,880,309...47,911,709
|
|
G
|
Mtor
|
mechanistic target of rapamycin kinase
|
multiple interactions
|
ISO
|
trigonelline inhibits the reaction [Palmitic Acid results in increased phosphorylation of MTOR protein]
|
CTD |
PMID:30208301 |
|
NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:158,884,804...158,994,311
|
|
G
|
Myc
|
MYC proto-oncogene, bHLH transcription factor
|
decreases expression
|
ISO
|
trigonelline results in decreased expression of MYC mRNA
|
CTD |
PMID:26593444 |
|
NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630
|
|
G
|
Nfe2l2
|
NFE2 like bZIP transcription factor 2
|
multiple interactions decreases phosphorylation
|
ISO EXP
|
trigonelline inhibits the reaction [EGF protein results in increased phosphorylation of NFE2L2 protein]; trigonelline inhibits the reaction [ferric citrate affects the localization of NFE2L2 protein]; trigonelline inhibits the reaction [NFE2L2 protein results in decreased susceptibility to Cisplatin]; trigonelline inhibits the reaction [NFE2L2 protein results in decreased susceptibility to Etoposide]; trigonelline inhibits the reaction [Pyocyanine results in increased expression of and affects the localization of NFE2L2 protein] oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of NFE2L2 protein]]; oltipraz inhibits the reaction [trigonelline affects the reaction [INS2 protein affects the expression of NFE2L2 mRNA]]; trigonelline affects the reaction [INS2 protein affects the expression of NFE2L2 mRNA]; trigonelline affects the reaction [INS2 protein affects the expression of NFE2L2 protein] oltipraz inhibits the reaction [trigonelline inhibits the reaction [Glucose results in increased expression of NFE2L2 protein]]; trigonelline inhibits the reaction [Glucose results in increased expression of NFE2L2 protein] trigonelline results in decreased phosphorylation of NFE2L2 protein
|
CTD |
PMID:24015256 PMID:29211853 PMID:29959986 PMID:33148531 |
|
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737
|
|
G
|
Nqo1
|
NAD(P)H quinone dehydrogenase 1
|
multiple interactions decreases expression
|
ISO
|
trigonelline inhibits the reaction [ferric citrate results in increased expression of NQO1 protein]; trigonelline inhibits the reaction [Pyocyanine results in increased expression of NQO1 mRNA] trigonelline results in decreased expression of NQO1 mRNA; trigonelline results in decreased expression of NQO1 protein
|
CTD |
PMID:24015256 PMID:29959986 PMID:33148531 |
|
NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557
|
|
G
|
Parp1
|
poly (ADP-ribose) polymerase 1
|
multiple interactions
|
ISO
|
trigonelline inhibits the reaction [Palmitic Acid results in increased cleavage of PARP1 protein] [trigonelline co-treated with Cisplatin] results in increased cleavage of PARP1 protein; [trigonelline co-treated with Etoposide] results in increased cleavage of PARP1 protein
|
CTD |
PMID:30208301 PMID:33148531 |
|
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:92,307,586...92,339,404
|
|
G
|
Plcg1
|
phospholipase C, gamma 1
|
multiple interactions
|
ISO
|
trigonelline inhibits the reaction [iodixanol results in increased phosphorylation of PLCG1 protein]
|
CTD |
PMID:34774977 |
|
NCBI chr 3:169,805,299...169,836,040
Ensembl chr 3:149,385,587...149,416,330
|
|
G
|
Plin1
|
perilipin 1
|
multiple interactions
|
ISO
|
trigonelline inhibits the reaction [Palmitic Acid results in increased expression of PLIN1 protein]
|
CTD |
PMID:30208301 |
|
NCBI chr 1:143,073,612...143,086,199
Ensembl chr 1:133,664,892...133,676,828
|
|
G
|
Pparg
|
peroxisome proliferator-activated receptor gamma
|
multiple interactions
|
ISO
|
ATG7 protein affects the reaction [trigonelline inhibits the reaction [Palmitic Acid results in increased expression of PPARG protein]]; trigonelline inhibits the reaction [Palmitic Acid results in increased expression of PPARG protein] trigonelline inhibits the reaction [[Cholesterol, Dietary co-treated with Dietary Fats] results in increased expression of PPARG protein]; trigonelline inhibits the reaction [Palmitic Acid results in increased expression of PPARG protein]
|
CTD |
PMID:30208301 |
|
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:148,423,194...148,548,468
|
|
G
|
Sqstm1
|
sequestosome 1
|
multiple interactions
|
ISO
|
trigonelline inhibits the reaction [[Cholesterol, Dietary co-treated with Dietary Fats] results in increased expression of SQSTM1 protein]; trigonelline inhibits the reaction [Palmitic Acid results in increased expression of SQSTM1 protein]
|
CTD |
PMID:30208301 |
|
NCBI chr10:35,026,598...35,037,750
Ensembl chr10:34,525,519...34,536,673
|
|
G
|
Srebf1
|
sterol regulatory element binding transcription factor 1
|
multiple interactions
|
ISO
|
trigonelline inhibits the reaction [[Cholesterol, Dietary co-treated with Dietary Fats] results in increased expression of SREBF1 protein]; trigonelline inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein] ATG7 protein affects the reaction [trigonelline inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein]]; trigonelline inhibits the reaction [Palmitic Acid results in increased expression of SREBF1 protein]
|
CTD |
PMID:30208301 |
|
NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,007,637...45,029,650
|
|
G
|
Tnf
|
tumor necrosis factor
|
multiple interactions
|
EXP
|
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [trigonelline inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of TNF protein]]; trigonelline inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of TNF protein]
|
CTD |
PMID:31935362 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
|
|
|
G
|
Ache
|
acetylcholinesterase
|
multiple interactions
|
EXP
|
Acetylcarnitine inhibits the reaction [Dexamethasone results in decreased activity of ACHE protein]; Acetylcarnitine inhibits the reaction [Dexamethasone results in increased activity of ACHE protein]
|
CTD |
PMID:21986892 |
|
NCBI chr12:25,042,882...25,050,608
Ensembl chr12:19,407,360...19,413,651
|
|
G
|
Apex1
|
apurinic/apyrimidinic endodeoxyribonuclease 1
|
increases expression
|
EXP
|
Acetylcarnitine results in increased expression of APEX1 mRNA
|
CTD |
PMID:14654561 |
|
NCBI chr15:26,618,146...26,620,330
Ensembl chr15:24,144,362...24,146,785
|
|
G
|
Atp6v1f
|
ATPase H+ transporting V1 subunit F
|
increases expression
|
EXP
|
Acetylcarnitine results in increased expression of ATP6V1F mRNA
|
CTD |
PMID:14654561 |
|
NCBI chr 4:59,033,020...59,035,980
|
|
G
|
C1qa
|
complement C1q A chain
|
decreases expression
|
ISO
|
Acetylcarnitine results in decreased expression of C1QA mRNA
|
CTD |
PMID:19555370 |
|
NCBI chr 5:154,417,086...154,419,933
Ensembl chr 5:149,133,636...149,136,534
|
|
G
|
C4b
|
complement C4B
|
decreases expression
|
ISO
|
Acetylcarnitine results in decreased expression of C4B mRNA
|
CTD |
PMID:19555370 |
|
NCBI chr20:4,201,979...4,216,292
Ensembl chr20:4,197,366...4,211,681
|
|
G
|
Casp3
|
caspase 3
|
multiple interactions
|
EXP
|
Acetylcarnitine inhibits the reaction [sodium arsenite results in increased activity of CASP3 protein]; Acetylcarnitine inhibits the reaction [Sodium Selenite results in increased expression of CASP3 mRNA]
|
CTD |
PMID:20067779 PMID:29278859 |
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648
|
|
G
|
Casp9
|
caspase 9
|
multiple interactions
|
EXP
|
Acetylcarnitine inhibits the reaction [sodium arsenite results in increased activity of CASP9 protein]
|
CTD |
PMID:29278859 |
|
Ensembl chr 5:154,109,046...154,126,626
|
|
G
|
Cat
|
catalase
|
multiple interactions
|
EXP
|
Acetylcarnitine inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]; Acetylcarnitine inhibits the reaction [Sodium Selenite results in decreased expression of CAT mRNA]
|
CTD |
PMID:20067779 PMID:26349760 PMID:29278859 |
|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478
|
|
G
|
Col2a1
|
collagen type II alpha 1 chain
|
multiple interactions
|
EXP
|
[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of Acetylcarnitine
|
CTD |
PMID:24709313 |
|
NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546
|
|
G
|
Cs
|
citrate synthase
|
decreases activity
|
EXP
|
Acetylcarnitine results in decreased activity of CS protein
|
CTD |
PMID:9821151 |
|
NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421
|
|
G
|
Ctss
|
cathepsin S
|
decreases expression
|
ISO
|
Acetylcarnitine results in decreased expression of CTSS mRNA
|
CTD |
PMID:19555370 |
|
NCBI chr 2:185,775,316...185,803,440
Ensembl chr 2:183,086,437...183,114,483
|
|
G
|
Cxcl14
|
C-X-C motif chemokine ligand 14
|
decreases expression
|
ISO
|
Acetylcarnitine results in decreased expression of CXCL14 mRNA
|
CTD |
PMID:19555370 |
|
NCBI chr17:8,317,930...8,325,956
Ensembl chr17:8,317,933...8,324,839
|
|
G
|
Egr1
|
early growth response 1
|
multiple interactions
|
EXP
|
Acetylcarnitine inhibits the reaction [Sodium Selenite results in increased expression of EGR1 mRNA]
|
CTD |
PMID:20067779 |
|
NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,462,981...26,466,766
|
|
G
|
Gfap
|
glial fibrillary acidic protein
|
decreases expression
|
ISO
|
Acetylcarnitine results in decreased expression of GFAP mRNA
|
CTD |
PMID:19555370 |
|
NCBI chr10:88,352,987...88,361,661
Ensembl chr10:87,852,890...87,861,589
|
|
G
|
Gsr
|
glutathione-disulfide reductase
|
multiple interactions
|
ISO
|
Acetylcarnitine inhibits the reaction [Acetaminophen results in decreased expression of GSR protein]
|
CTD |
PMID:26265018 |
|
NCBI chr16:65,185,574...65,228,742
Ensembl chr16:58,482,505...58,525,661
|
|
G
|
Gstp1
|
glutathione S-transferase pi 1
|
multiple interactions
|
EXP
|
Acetylcarnitine affects the reaction [Dexamethasone results in decreased expression of GSTP1 mRNA]
|
CTD |
PMID:21986892 |
|
NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226
|
|
G
|
Hmox1
|
heme oxygenase 1
|
multiple interactions
|
EXP
|
Acetylcarnitine affects the reaction [Dexamethasone results in increased expression of HMOX1 mRNA]
|
CTD |
PMID:21986892 |
|
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079
|
|
G
|
Hmox2
|
heme oxygenase 2
|
multiple interactions
|
EXP
|
Acetylcarnitine affects the reaction [Dexamethasone results in increased expression of HMOX2 mRNA]
|
CTD |
PMID:21986892 |
|
NCBI chr10:10,797,076...10,831,178
Ensembl chr10:10,797,055...10,831,148
|
|
G
|
Hspb1
|
heat shock protein family B (small) member 1
|
decreases expression
|
EXP
|
Acetylcarnitine results in decreased expression of HSPB1 mRNA
|
CTD |
PMID:14654561 |
|
NCBI chr12:26,430,640...26,432,301
Ensembl chr12:20,794,028...20,795,743
|
|
G
|
Idh2
|
isocitrate dehydrogenase (NADP(+)) 2
|
increases abundance multiple interactions
|
ISO
|
IDH2 protein mutant form results in increased abundance of Acetylcarnitine Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Acetylcarnitine]
|
CTD |
PMID:27469509 |
|
NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:134,029,772...134,058,025
|
|
G
|
Il1b
|
interleukin 1 beta
|
multiple interactions
|
EXP
|
Acetylcarnitine inhibits the reaction [sodium arsenite results in increased expression of IL1B protein]
|
CTD |
PMID:29278859 |
|
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415
|
|
G
|
Il6
|
interleukin 6
|
multiple interactions
|
EXP
|
Acetylcarnitine inhibits the reaction [sodium arsenite results in increased expression of IL6 protein]
|
CTD |
PMID:29278859 |
|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178
|
|
G
|
Mgst1
|
microsomal glutathione S-transferase 1
|
increases expression
|
EXP
|
Acetylcarnitine results in increased expression of MGST1 mRNA
|
CTD |
PMID:14654561 |
|
NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892
|
|
G
|
Mt-co1
|
mitochondrially encoded cytochrome c oxidase I
|
multiple interactions
|
EXP
|
Acetylcarnitine inhibits the reaction [Sodium Selenite results in decreased expression of COX1 mRNA]
|
CTD |
PMID:20067779 |
|
NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
|
|
G
|
Ngf
|
nerve growth factor
|
multiple interactions
|
EXP
|
Acetylcarnitine inhibits the reaction [Cisplatin results in decreased expression of NGF protein]
|
CTD |
PMID:14654561 |
|
NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:189,901,058...189,954,452
|
|
G
|
Nos1
|
nitric oxide synthase 1
|
multiple interactions
|
EXP
|
Acetylcarnitine affects the reaction [Dexamethasone results in increased expression of NOS1 mRNA]
|
CTD |
PMID:21986892 |
|
NCBI chr12:44,276,011...44,456,371
Ensembl chr12:38,626,714...38,710,945
|
|
G
|
Nos2
|
nitric oxide synthase 2
|
multiple interactions
|
EXP
|
Acetylcarnitine affects the reaction [Dexamethasone results in increased expression of NOS2 mRNA]
|
CTD |
PMID:21986892 |
|
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:63,815,308...63,851,210
|
|
G
|
Pah
|
phenylalanine hydroxylase
|
decreases expression
|
ISO
|
Acetylcarnitine results in decreased expression of PAH mRNA
|
CTD |
PMID:19555370 |
|
NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:21,933,179...21,998,130
|
|
G
|
Pink1
|
PTEN induced kinase 1
|
multiple interactions
|
ISO
|
Acetylcarnitine inhibits the reaction [Cadmium results in increased expression of PINK1]
|
CTD |
PMID:25464205 |
|
NCBI chr 5:155,813,838...155,825,950
Ensembl chr 5:150,530,523...150,542,635
|
|
G
|
Ppargc1a
|
PPARG coactivator 1 alpha
|
increases expression multiple interactions
|
ISO
|
Acetylcarnitine results in increased expression of PPARGC1A protein [Acetylcarnitine co-treated with Thioctic Acid] results in increased expression of PPARGC1A protein
|
CTD |
PMID:20414966 |
|
NCBI chr14:63,073,505...63,729,215
Ensembl chr14:58,861,144...59,512,656
|
|
G
|
Prkn
|
parkin RBR E3 ubiquitin protein ligase
|
multiple interactions
|
ISO
|
Acetylcarnitine inhibits the reaction [Cadmium results in increased expression of PRKN]
|
CTD |
PMID:25464205 |
|
NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:48,690,556...49,882,555
|
|
G
|
Psmb6
|
proteasome 20S subunit beta 6
|
increases expression
|
EXP
|
Acetylcarnitine results in increased expression of PSMB6 mRNA
|
CTD |
PMID:14654561 |
|
NCBI chr10:55,239,256...55,241,586
Ensembl chr10:55,239,241...55,241,586
|
|
G
|
Ptma
|
prothymosin alpha
|
increases expression
|
EXP
|
Acetylcarnitine results in increased expression of PTMA mRNA
|
CTD |
PMID:14654561 |
|
NCBI chr 9:87,176,251...87,180,333
Ensembl chr 9:87,176,230...87,180,333
|
|
G
|
Rela
|
RELA proto-oncogene, NF-kB subunit
|
multiple interactions
|
EXP
|
Acetylcarnitine inhibits the reaction [sodium arsenite results in increased expression of RELA protein]
|
CTD |
PMID:29278859 |
|
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484
|
|
G
|
Rps17
|
ribosomal protein S17
|
increases expression
|
EXP
|
Acetylcarnitine results in increased expression of RPS17 mRNA
|
CTD |
PMID:14654561 |
|
NCBI chr 1:135,295,920...135,298,506
Ensembl chr 1:135,295,919...135,298,535 Ensembl chr 8:135,295,919...135,298,535
|
|
G
|
Skap2
|
src kinase associated phosphoprotein 2
|
decreases expression
|
ISO
|
Acetylcarnitine results in decreased expression of SKAP2 mRNA
|
CTD |
PMID:19555370 |
|
NCBI chr 4:80,948,832...81,100,900
Ensembl chr 4:80,950,580...81,100,891
|
|
G
|
Slc25a20
|
solute carrier family 25 member 20
|
multiple interactions
|
EXP
|
Acetylcarnitine inhibits the reaction [Hydrogen Peroxide results in decreased activity of SLC25A20 protein]
|
CTD |
PMID:23402788 |
|
NCBI chr 8:118,243,573...118,265,027
Ensembl chr 8:109,365,002...109,386,512
|
|
G
|
Snca
|
synuclein alpha
|
multiple interactions
|
ISO
|
[Acetylcarnitine co-treated with Thioctic Acid] inhibits the reaction [Rotenone results in increased expression of SNCA protein]; Acetylcarnitine inhibits the reaction [Rotenone results in increased expression of SNCA protein]
|
CTD |
PMID:20414966 |
|
NCBI chr 4:91,026,474...91,127,444
Ensembl chr 4:89,696,420...89,796,262
|
|
G
|
Tnni3
|
troponin I3, cardiac type
|
multiple interactions
|
EXP
|
Acetylcarnitine inhibits the reaction [Cisplatin results in increased expression of TNNI3 protein]
|
CTD |
PMID:21034734 |
|
NCBI chr 1:69,299,900...69,303,582
Ensembl chr 1:69,299,900...69,303,580
|
|
|
G
|
Idh2
|
isocitrate dehydrogenase (NADP(+)) 2
|
multiple interactions increases abundance
|
ISO
|
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of butyrylcarnitine]
|
CTD |
PMID:27469509 |
|
NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:134,029,772...134,058,025
|
|
|
G
|
Crot
|
carnitine O-octanoyltransferase
|
increases chemical synthesis
|
ISO
|
CROT protein results in increased chemical synthesis of octanoylcarnitine
|
CTD |
PMID:6838215 |
|
NCBI chr 4:26,031,729...26,088,057
Ensembl chr 4:25,080,587...25,133,109
|
|
|
G
|
Col2a1
|
collagen type II alpha 1 chain
|
multiple interactions
|
EXP
|
[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of Palmitoylcarnitine
|
CTD |
PMID:24709313 |
|
NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546
|
|
G
|
Gls
|
glutaminase
|
increases chemical synthesis
|
ISO
|
GLS protein results in increased chemical synthesis of Palmitoylcarnitine
|
CTD |
PMID:31040181 |
|
NCBI chr 9:56,836,584...56,908,861
Ensembl chr 9:49,344,781...49,416,900
|
|
G
|
Ppp3r1
|
protein phosphatase 3, regulatory subunit B, alpha
|
decreases metabolic processing
|
ISO
|
PPP3R1 gene mutant form results in decreased metabolism of Palmitoylcarnitine
|
CTD |
PMID:19700627 |
|
NCBI chr14:95,758,333...95,808,015
Ensembl chr14:91,604,121...91,606,907
|
|
G
|
Prkaa1
|
protein kinase AMP-activated catalytic subunit alpha 1
|
increases chemical synthesis
|
ISO
|
PRKAA1 protein results in increased chemical synthesis of Palmitoylcarnitine
|
CTD |
PMID:31040181 |
|
NCBI chr 2:55,967,766...56,003,450
Ensembl chr 2:54,240,137...54,275,978
|
|
|
G
|
App
|
amyloid beta precursor protein
|
increases abundance multiple interactions
|
ISO
|
APP protein mutant form results in increased abundance of propionylcarnitine PF-06840003 inhibits the reaction [APP protein mutant form results in increased abundance of propionylcarnitine] [APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with PF-06840003] results in decreased abundance of propionylcarnitine
|
CTD |
PMID:39172838 |
|
NCBI chr11:37,506,207...37,724,351
Ensembl chr11:24,019,778...24,236,561
|
|
G
|
Mapt
|
microtubule-associated protein tau
|
decreases abundance multiple interactions
|
ISO
|
MAPT protein mutant form results in decreased abundance of propionylcarnitine PF-06840003 inhibits the reaction [MAPT protein mutant form results in decreased abundance of propionylcarnitine]
|
CTD |
PMID:39172838 |
|
NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,138,627...89,236,129
|
|
G
|
Psen1
|
presenilin 1
|
multiple interactions
|
ISO
|
[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with PF-06840003] results in decreased abundance of propionylcarnitine
|
CTD |
PMID:39172838 |
|
NCBI chr 6:109,054,160...109,106,191
Ensembl chr 6:103,323,120...103,371,650
|
|
|
G
|
App
|
amyloid beta precursor protein
|
multiple interactions increases secretion
|
ISO
|
Phosphoenolpyruvate inhibits the reaction [Rotenone results in decreased secretion of APP protein modified form] Phosphoenolpyruvate results in increased secretion of APP protein modified form
|
CTD |
PMID:22906069 |
|
NCBI chr11:37,506,207...37,724,351
Ensembl chr11:24,019,778...24,236,561
|
|
G
|
Mapt
|
microtubule-associated protein tau
|
multiple interactions
|
ISO
|
[amyloid beta-protein (1-42) binds to MAPT protein] which results in decreased abundance of Phosphoenolpyruvate; PF-06840003 inhibits the reaction [[amyloid beta-protein (1-42) binds to MAPT protein] which results in decreased abundance of Phosphoenolpyruvate]
|
CTD |
PMID:39172838 |
|
NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,138,627...89,236,129
|
|
G
|
Pkm
|
pyruvate kinase M1/2
|
multiple interactions increases metabolic processing
|
ISO
|
3-hydroxyflavone inhibits the reaction [PKM protein results in increased metabolism of Phosphoenolpyruvate]; 5-hydroxyflavone inhibits the reaction [PKM protein results in increased metabolism of Phosphoenolpyruvate]; 6-hydroxyflavone inhibits the reaction [PKM protein results in increased metabolism of Phosphoenolpyruvate]; 7-hydroxyflavone inhibits the reaction [PKM protein results in increased metabolism of Phosphoenolpyruvate]; Apigenin inhibits the reaction [PKM protein results in increased metabolism of Phosphoenolpyruvate]; flavone inhibits the reaction [PKM protein results in increased metabolism of Phosphoenolpyruvate]; wogonin inhibits the reaction [PKM protein results in increased metabolism of Phosphoenolpyruvate]
|
CTD |
PMID:25388478 |
|
NCBI chr 8:68,949,731...68,975,394
Ensembl chr 8:60,057,402...60,079,599
|
|
|
G
|
Ache
|
acetylcholinesterase
|
decreases activity
|
ISO
|
physostigmine salicylate results in decreased activity of ACHE protein
|
CTD |
PMID:623676 |
|
NCBI chr12:25,042,882...25,050,608
Ensembl chr12:19,407,360...19,413,651
|
|
|
G
|
Abca1
|
ATP binding cassette subfamily A member 1
|
multiple interactions increases expression
|
EXP ISO
|
GW 6471 inhibits the reaction [pitavastatin results in increased expression of ABCA1 mRNA] pitavastatin inhibits the reaction [8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of ABCA1 protein] GW 6471 inhibits the reaction [pitavastatin results in increased expression of ABCA1 mRNA]; PPARA protein affects the reaction [pitavastatin results in increased expression of ABCA1 mRNA]
|
CTD |
PMID:16415093 PMID:21554872 |
|
NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:67,681,297...67,801,170
|
|
G
|
Abcb11
|
ATP binding cassette subfamily B member 11
|
multiple interactions decreases activity
|
ISO
|
pitavastatin inhibits the reaction [ABCB11 protein affects the import of Taurocholic Acid]; pitavastatin inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid] pitavastatin results in decreased activity of ABCB11 protein
|
CTD |
PMID:15901796 PMID:24014644 |
|
NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:54,017,127...54,112,730
|
|
G
|
Abcb1a
|
ATP binding cassette subfamily B member 1A
|
affects transport
|
ISO
|
ABCB1 protein affects the transport of pitavastatin
|
CTD |
PMID:15955871 |
|
NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:25,158,362...25,442,709
|
|
G
|
Abcc2
|
ATP binding cassette subfamily C member 2
|
multiple interactions affects transport
|
EXP ISO
|
ABCC2 protein binds to and results in increased uptake of pitavastatin analog; pitavastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein] ABCC2 protein affects the transport of pitavastatin
|
CTD |
PMID:15955871 PMID:23562342 |
|
NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:242,664,657...242,723,238
|
|
G
|
Abcg2
|
ATP binding cassette subfamily G member 2
|
affects transport
|
ISO
|
ABCG2 protein affects the transport of pitavastatin
|
CTD |
PMID:15955871 |
|
NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:87,745,319...87,802,409
|
|
G
|
Atf4
|
activating transcription factor 4
|
multiple interactions increases expression
|
ISO
|
EIF2AK3 protein affects the reaction [pitavastatin results in increased expression of ATF4 protein]
|
CTD |
PMID:37956312 |
|
NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:111,804,183...111,806,446
|
|
G
|
Bbc3
|
Bcl-2 binding component 3
|
multiple interactions increases expression affects response to substance
|
ISO
|
BBC3 protein affects the susceptibility to [S63845 co-treated with pitavastatin]; BBC3 protein affects the susceptibility to [venetoclax co-treated with pitavastatin] pitavastatin results in increased expression of BBC3 mRNA; pitavastatin results in increased expression of BBC3 protein BBC3 protein affects the susceptibility to pitavastatin
|
CTD |
PMID:37956312 |
|
NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:77,014,543...77,022,509
|
|
G
|
Casp3
|
caspase 3
|
increases activity
|
ISO
|
pitavastatin results in increased activity of CASP3 protein
|
CTD |
PMID:38053498 |
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648
|
|
G
|
Casp8
|
caspase 8
|
multiple interactions
|
ISO
|
[pitavastatin co-treated with Cisplatin] results in decreased activity of CASP8 protein
|
CTD |
PMID:38053498 |
|
NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:60,264,075...60,312,542
|
|
G
|
Casp9
|
caspase 9
|
increases activity
|
ISO
|
pitavastatin results in increased activity of CASP9 protein
|
CTD |
PMID:38053498 |
|
Ensembl chr 5:154,109,046...154,126,626
|
|
G
|
Ccl2
|
C-C motif chemokine ligand 2
|
multiple interactions
|
ISO
|
pitavastatin inhibits the reaction [LEP gene mutant form results in increased expression of CCL2 mRNA]; pitavastatin inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]
|
CTD |
PMID:18323514 |
|
NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,005,424...67,007,226
|
|
G
|
Eif2ak3
|
eukaryotic translation initiation factor 2 alpha kinase 3
|
multiple interactions
|
ISO
|
EIF2AK3 protein affects the reaction [pitavastatin results in increased expression of ATF4 protein]
|
CTD |
PMID:37956312 |
|
NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:102,805,510...102,866,911
|
|
G
|
Foxo1
|
forkhead box O1
|
decreases phosphorylation
|
ISO
|
pitavastatin results in decreased phosphorylation of FOXO1 protein
|
CTD |
PMID:33034787 |
|
NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:136,312,168...136,387,790
|
|
G
|
Ifnb1
|
interferon beta 1
|
multiple interactions
|
ISO
|
pitavastatin inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA]; pitavastatin inhibits the reaction [Palmitic Acid results in increased expression of IFNB1 mRNA]; pitavastatin inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]
|
CTD |
PMID:18323514 |
|
NCBI chr 5:108,066,650...108,067,487
Ensembl chr 5:103,020,969...103,021,523
|
|
G
|
Il6
|
interleukin 6
|
multiple interactions
|
ISO
|
pitavastatin inhibits the reaction [LEP gene mutant form results in increased expression of IL6 mRNA]; pitavastatin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; pitavastatin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; pitavastatin inhibits the reaction [Palmitic Acid results in increased expression of IL6 mRNA]; pitavastatin inhibits the reaction [Poly I-C results in increased expression of IL6 mRNA]
|
CTD |
PMID:18323514 |
|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178
|
|
G
|
Irf3
|
interferon regulatory factor 3
|
multiple interactions
|
ISO
|
pitavastatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of IRF3 protein]; pitavastatin inhibits the reaction [Palmitic Acid results in increased phosphorylation of IRF3 protein]
|
CTD |
PMID:18323514 |
|
NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935
|
|
G
|
Irf4
|
interferon regulatory factor 4
|
decreases expression
|
ISO
|
pitavastatin results in decreased expression of IRF4 protein
|
CTD |
PMID:33034787 |
|
NCBI chr17:33,930,460...33,948,842
Ensembl chr17:33,721,811...33,740,070
|
|
G
|
Lep
|
leptin
|
multiple interactions
|
ISO
|
pitavastatin inhibits the reaction [LEP gene mutant form results in increased expression of CCL2 mRNA]; pitavastatin inhibits the reaction [LEP gene mutant form results in increased expression of IL6 mRNA]; pitavastatin inhibits the reaction [LEP gene mutant form results in increased expression of TNF mRNA]
|
CTD |
PMID:18323514 |
|
NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:57,661,131...57,675,262
|
|
G
|
Mstn
|
myostatin
|
increases expression
|
ISO
|
pitavastatin results in increased expression of MSTN protein
|
CTD |
PMID:33034787 |
|
NCBI chr 9:48,452,533...48,458,933
Ensembl chr 9:48,452,533...48,458,933
|
|
G
|
Nos2
|
nitric oxide synthase 2
|
multiple interactions
|
ISO
|
pitavastatin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; pitavastatin inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA]; pitavastatin inhibits the reaction [Poly I-C results in increased expression of NOS2 mRNA]
|
CTD |
PMID:18323514 |
|
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:63,815,308...63,851,210
|
|
G
|
Nr1h2
|
nuclear receptor subfamily 1, group H, member 2
|
multiple interactions
|
ISO
|
NR1H2 gene mutant form inhibits the reaction [pitavastatin inhibits the reaction [8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased export of Cholesterol]]; NR1H2 gene mutant form inhibits the reaction [pitavastatin results in decreased export of Cholesterol]
|
CTD |
PMID:16415093 |
|
NCBI chr 1:95,041,967...95,047,358
Ensembl chr 1:95,041,967...95,047,377
|
|
G
|
Nr1h3
|
nuclear receptor subfamily 1, group H, member 3
|
multiple interactions
|
ISO
|
NR1H3 gene mutant form inhibits the reaction [pitavastatin inhibits the reaction [8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased export of Cholesterol]]; NR1H3 gene mutant form inhibits the reaction [pitavastatin results in decreased export of Cholesterol]
|
CTD |
PMID:16415093 |
|
NCBI chr 3:97,614,616...97,632,053
Ensembl chr 3:77,158,808...77,168,722
|
|
G
|
Parp1
|
poly (ADP-ribose) polymerase 1
|
increases cleavage
|
ISO
|
pitavastatin results in increased cleavage of PARP1 protein
|
CTD |
PMID:37956312 PMID:38053498 |
|
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:92,307,586...92,339,404
|
|
G
|
Pmaip1
|
phorbol-12-myristate-13-acetate-induced protein 1
|
multiple interactions increases expression
|
ISO
|
2-(4-chlorophenoxy)-N-(4-(2-(4-chlorophenoxy)acetamido)cyclohexyl)acetamide inhibits the reaction [pitavastatin results in increased expression of PMAIP1 protein]
|
CTD |
PMID:37956312 |
|
NCBI chr18:62,255,970...62,262,384
Ensembl chr18:59,986,017...59,992,429
|
|
G
|
Pon1
|
paraoxonase 1
|
multiple interactions increases expression
|
ISO
|
farnesyl pyrophosphate inhibits the reaction [pitavastatin results in increased expression of PON1 mRNA]; Mevalonic Acid inhibits the reaction [pitavastatin results in increased expression of PON1 mRNA]; Plicamycin inhibits the reaction [pitavastatin results in increased expression of PON1 mRNA]
|
CTD |
PMID:15690306 |
|
NCBI chr 4:34,261,312...34,292,327
Ensembl chr 4:33,294,722...33,321,360
|
|
G
|
Ppara
|
peroxisome proliferator activated receptor alpha
|
multiple interactions increases expression
|
ISO
|
pitavastatin promotes the reaction [Bezafibrate results in increased activity of [PPARA protein binds to RXRA protein]]; PPARA protein affects the reaction [pitavastatin results in increased expression of ABCA1 mRNA] pitavastatin results in increased expression of PPARA mRNA
|
CTD |
PMID:11779144 PMID:21554872 |
|
NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346
|
|
G
|
Ppard
|
peroxisome proliferator-activated receptor delta
|
increases expression
|
ISO
|
pitavastatin results in increased expression of PPARD mRNA
|
CTD |
PMID:21554872 |
|
NCBI chr20:6,300,527...6,365,707
Ensembl chr20:6,298,785...6,363,968
|
|
G
|
Rap1a
|
RAP1A, member of RAS oncogene family
|
decreases prenylation decreases expression
|
ISO
|
pitavastatin results in decreased prenylation of RAP1A protein pitavastatin results in decreased expression of RAP1A protein alternative form
|
CTD |
PMID:37956312 |
|
NCBI chr 2:195,896,967...195,974,851
Ensembl chr 2:193,208,635...193,286,501
|
|
G
|
Rxra
|
retinoid X receptor alpha
|
multiple interactions
|
ISO
|
pitavastatin promotes the reaction [Bezafibrate results in increased activity of [PPARA protein binds to RXRA protein]]
|
CTD |
PMID:11779144 |
|
NCBI chr 3:31,387,892...31,474,415
Ensembl chr 3:10,989,832...11,073,712
|
|
G
|
Slco1a4
|
solute carrier organic anion transporter family, member 1a4
|
affects transport
|
ISO
|
SLCO1A4 protein affects the transport of pitavastatin
|
CTD |
PMID:19833843 |
|
NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573
|
|
G
|
Stat1
|
signal transducer and activator of transcription 1
|
multiple interactions
|
ISO
|
pitavastatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT1 protein]
|
CTD |
PMID:18323514 |
|
NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:49,419,340...49,588,540
|
|
G
|
Tnf
|
tumor necrosis factor
|
multiple interactions
|
ISO
|
pitavastatin inhibits the reaction [LEP gene mutant form results in increased expression of TNF mRNA]; pitavastatin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]
|
CTD |
PMID:18323514 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
|
|
|
G
|
Abcb1a
|
ATP binding cassette subfamily B member 1A
|
decreases activity
|
ISO
|
Rose Bengal results in decreased activity of ABCB1 protein
|
CTD |
PMID:20041016 |
|
NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:25,158,362...25,442,709
|
|
G
|
Cyp19a1
|
cytochrome P450, family 19, subfamily a, polypeptide 1
|
decreases activity
|
EXP
|
Rose Bengal results in decreased activity of CYP19A1 protein
|
CTD |
PMID:18310892 |
|
NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:54,553,165...54,580,758
|
|
G
|
Cyp3a2
|
cytochrome P450, family 3, subfamily a, polypeptide 2
|
decreases activity
|
ISO
|
Rose Bengal results in decreased activity of CYP3A4 protein
|
CTD |
PMID:20041016 |
|
NCBI chr12:14,321,771...14,343,886
Ensembl chr12:9,015,383...9,285,008
|
|
G
|
Gsta3
|
glutathione S-transferase alpha 3
|
decreases response to substance
|
EXP
|
GSTA3 protein results in decreased susceptibility to Rose Bengal
|
CTD |
PMID:1740415 |
|
NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
|
|
G
|
Iyd
|
iodotyrosine deiodinase
|
decreases activity
|
ISO
|
Rose Bengal results in decreased activity of IYD protein
|
CTD |
PMID:24012475 |
|
NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
|
|
G
|
Kcnh2
|
potassium voltage-gated channel subfamily H member 2
|
decreases activity
|
ISO
|
Rose Bengal results in decreased activity of KCNH2 protein
|
CTD |
PMID:28551711 |
|
NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:10,826,928...10,859,008
|
|
G
|
Klkb1
|
kallikrein B1
|
multiple interactions decreases response to substance
|
ISO
|
7-Ala-angiotensin (1-7) inhibits the reaction [KLKB1 gene mutant form results in decreased susceptibility to Rose Bengal]; nimesulide inhibits the reaction [KLKB1 gene mutant form results in decreased susceptibility to Rose Bengal]; splitomicin inhibits the reaction [KLKB1 gene mutant form results in decreased susceptibility to Rose Bengal]
|
CTD |
PMID:25339356 |
|
NCBI chr16:53,690,180...53,714,570
Ensembl chr16:46,958,707...46,982,053
|
|
G
|
Ugt1a6
|
UDP glucuronosyltransferase family 1 member A6
|
decreases activity
|
ISO
|
Rose Bengal results in decreased activity of UGT1A6 protein
|
CTD |
PMID:20041016 |
|
NCBI chr 9:96,195,018...96,256,264
Ensembl chr 9:88,713,184...88,808,465
|
|
|
G
|
Abca1
|
ATP binding cassette subfamily A member 1
|
decreases expression multiple interactions
|
ISO
|
Rosuvastatin Calcium results in decreased expression of ABCA1 mRNA Lipopolysaccharides inhibits the reaction [Rosuvastatin Calcium results in decreased expression of ABCA1 mRNA]
|
CTD |
PMID:18192897 |
|
NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:67,681,297...67,801,170
|
|
G
|
Abcb11
|
ATP binding cassette subfamily B member 11
|
multiple interactions
|
ISO EXP
|
Rosuvastatin Calcium inhibits the reaction [ABCB11 protein affects the import of Taurocholic Acid] [Cyclosporine results in decreased activity of ABCB11 protein] which results in decreased secretion of Rosuvastatin Calcium; [Glyburide results in decreased activity of ABCB11 protein] which results in decreased secretion of Rosuvastatin Calcium; [troglitazone results in decreased activity of ABCB11 protein] which results in decreased secretion of Rosuvastatin Calcium
|
CTD |
PMID:15901796 PMID:19853032 |
|
NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:54,017,127...54,112,730
|
|
G
|
Abcc2
|
ATP binding cassette subfamily C member 2
|
multiple interactions increases expression affects secretion
|
ISO EXP
|
ABCC2 protein binds to and results in increased uptake of Rosuvastatin Calcium analog; Rosuvastatin Calcium analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein] Rosuvastatin Calcium results in increased expression of ABCC2 protein [Benzbromarone results in decreased activity of ABCC2 protein] which results in decreased secretion of Rosuvastatin Calcium; [Probenecid results in decreased activity of ABCC2 protein] which results in decreased secretion of Rosuvastatin Calcium; [Sulfasalazine results in decreased activity of ABCC2 protein] which results in decreased secretion of Rosuvastatin Calcium; ABCC2 protein binds to and results in increased uptake of Rosuvastatin Calcium analog; Rosuvastatin Calcium analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Rosuvastatin Calcium promotes the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein] ABCC2 protein affects the secretion of Rosuvastatin Calcium
|
CTD |
PMID:19853032 PMID:23562342 PMID:24909372 |
|
NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:242,664,657...242,723,238
|
|
G
|
Abcc3
|
ATP binding cassette subfamily C member 3
|
increases expression
|
EXP
|
Rosuvastatin Calcium results in increased expression of ABCC3 protein
|
CTD |
PMID:24909372 |
|
NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,296,693...79,342,595
|
|
G
|
Abcg1
|
ATP binding cassette subfamily G member 1
|
decreases expression
|
ISO
|
Rosuvastatin Calcium results in decreased expression of ABCG1 mRNA
|
CTD |
PMID:18192897 |
|
NCBI chr20:9,128,056...9,184,312
Ensembl chr20:9,126,687...9,182,948
|
|
G
|
Abcg2
|
ATP binding cassette subfamily G member 2
|
multiple interactions increases activity
|
EXP ISO
|
[Novobiocin results in decreased activity of ABCG2 protein] which results in decreased secretion of Rosuvastatin Calcium Rosuvastatin Calcium results in increased activity of ABCG2 protein
|
CTD |
PMID:19853032 PMID:30083819 |
|
NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:87,745,319...87,802,409
|
|
G
|
Ache
|
acetylcholinesterase
|
multiple interactions
|
EXP
|
[Piracetam co-treated with Rosuvastatin Calcium] inhibits the reaction [[Sodium Chloride, Dietary co-treated with Cholesterol, Dietary co-treated with Coconut Oil] results in increased activity of ACHE protein]; Rosuvastatin Calcium inhibits the reaction [[Sodium Chloride, Dietary co-treated with Cholesterol, Dietary co-treated with Coconut Oil] results in increased activity of ACHE protein]
|
CTD |
PMID:28441890 |
|
NCBI chr12:25,042,882...25,050,608
Ensembl chr12:19,407,360...19,413,651
|
|
G
|
Akt1
|
AKT serine/threonine kinase 1
|
affects phosphorylation
|
EXP
|
Rosuvastatin Calcium affects the phosphorylation of AKT1 protein
|
CTD |
PMID:27815113 |
|
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921
|
|
G
|
Apoa1
|
apolipoprotein A1
|
multiple interactions increases expression
|
ISO
|
Niacin promotes the reaction [Rosuvastatin Calcium results in increased expression of APOA1 protein]
|
CTD |
PMID:12767421 PMID:15539964 |
|
NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:46,527,144...46,529,035
|
|
G
|
Apob
|
apolipoprotein B
|
decreases expression
|
ISO
|
Rosuvastatin Calcium results in decreased expression of APOB protein
|
CTD |
PMID:15539964 PMID:18702965 |
|
NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
|
|
G
|
Bax
|
BCL2 associated X, apoptosis regulator
|
multiple interactions
|
EXP
|
Rosuvastatin Calcium inhibits the reaction [Isoproterenol results in increased expression of BAX mRNA]
|
CTD |
PMID:32007421 |
|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368
|
|
G
|
Bcl2
|
BCL2, apoptosis regulator
|
decreases expression
|
ISO
|
Rosuvastatin Calcium results in decreased expression of BCL2 protein
|
CTD |
PMID:20852871 |
|
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
|
|
G
|
C3
|
complement C3
|
decreases expression
|
ISO
|
Rosuvastatin Calcium results in decreased expression of C3 mRNA
|
CTD |
PMID:32771489 |
|
NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,087,437...2,114,429
|
|
G
|
Casp3
|
caspase 3
|
increases activity increases expression
|
ISO
|
Rosuvastatin Calcium results in increased activity of CASP3 protein Rosuvastatin Calcium results in increased expression of CASP3 protein
|
CTD |
PMID:21478229 PMID:32771489 |
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648
|
|
G
|
Cat
|
catalase
|
increases activity multiple interactions
|
EXP
|
Rosuvastatin Calcium results in increased activity of CAT protein [Rosuvastatin Calcium co-treated with Isoproterenol] inhibits the reaction [Interleukin-6 results in increased expression of CAT protein]; Rosuvastatin Calcium inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]
|
CTD |
PMID:20146376 PMID:32007421 PMID:35130744 |
|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478
|
|
G
|
Ccl2
|
C-C motif chemokine ligand 2
|
decreases expression
|
EXP
|
Rosuvastatin Calcium results in decreased expression of CCL2 mRNA
|
CTD |
PMID:15681303 |
|
NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,005,424...67,007,226
|
|
G
|
Creb5
|
cAMP responsive element binding protein 5
|
decreases expression
|
ISO
|
Rosuvastatin Calcium results in decreased expression of CREB5 mRNA
|
CTD |
PMID:18192897 |
|
NCBI chr 4:82,393,091...82,794,320
Ensembl chr 4:82,393,730...82,790,325
|
|
G
|
Crp
|
C-reactive protein
|
multiple interactions
|
ISO
|
Rosuvastatin Calcium inhibits the reaction [CRP protein results in decreased expression of NOS3]
|
CTD |
PMID:21562509 |
|
NCBI chr13:87,694,062...87,695,978
Ensembl chr13:85,124,977...85,175,178
|
|
G
|
Cyba
|
cytochrome b-245 alpha chain
|
multiple interactions decreases expression
|
EXP
|
[[[Rosuvastatin Calcium results in decreased expression of CYBB] co-treated with [Rosuvastatin Calcium results in decreased expression of CYBA]] co-treated with [Rosuvastatin Calcium results in increased expression of SOD1]] results in decreased abundance of Reactive Oxygen Species
|
CTD |
PMID:21562509 |
|
NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
|
|
G
|
Cybb
|
cytochrome b-245 beta chain
|
multiple interactions decreases expression
|
ISO EXP
|
Rosuvastatin Calcium inhibits the reaction [Nitroglycerin results in increased expression of CYBB mRNA] [[[Rosuvastatin Calcium results in decreased expression of CYBB] co-treated with [Rosuvastatin Calcium results in decreased expression of CYBA]] co-treated with [Rosuvastatin Calcium results in increased expression of SOD1]] results in decreased abundance of Reactive Oxygen Species
|
CTD |
PMID:16633368 PMID:21562509 |
|
NCBI chr X:16,030,596...16,065,065
Ensembl chr X:13,359,430...13,392,586
|
|
G
|
Esr1
|
estrogen receptor 1
|
decreases expression
|
ISO
|
Rosuvastatin Calcium results in decreased expression of ESR1 protein
|
CTD |
PMID:32771489 |
|
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002
|
|
G
|
Gclc
|
glutamate-cysteine ligase, catalytic subunit
|
increases expression multiple interactions
|
ISO
|
Rosuvastatin Calcium results in increased expression of GCLC mRNA [Tetradecanoylphorbol Acetate co-treated with Rosuvastatin Calcium] results in increased expression of GCLC mRNA
|
CTD |
PMID:18154958 |
|
NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:78,630,127...78,668,544
|
|
G
|
Gpr183
|
G protein-coupled receptor 183
|
multiple interactions increases expression
|
ISO
|
Lipopolysaccharides inhibits the reaction [Rosuvastatin Calcium results in increased expression of GPR183 mRNA]
|
CTD |
PMID:18192897 |
|
NCBI chr15:105,445,129...105,457,192
Ensembl chr15:99,036,367...99,050,559
|
|
G
|
Gzmk
|
granzyme K
|
multiple interactions increases expression
|
ISO
|
Lipopolysaccharides inhibits the reaction [Rosuvastatin Calcium results in increased expression of GZMK mRNA]
|
CTD |
PMID:18192897 |
|
NCBI chr 2:44,840,811...44,848,829
Ensembl chr 2:44,840,811...44,848,894
|
|
G
|
Hnf4a
|
hepatocyte nuclear factor 4, alpha
|
increases secretion
|
ISO
|
HNF4A protein results in increased secretion of Rosuvastatin Calcium
|
CTD |
PMID:27160211 |
|
NCBI chr 3:172,606,220...172,667,758
Ensembl chr 3:152,186,787...152,248,320
|
|
G
|
Il18rap
|
interleukin 18 receptor accessory protein
|
decreases expression multiple interactions
|
ISO
|
Rosuvastatin Calcium results in decreased expression of IL18RAP mRNA Lipopolysaccharides inhibits the reaction [Rosuvastatin Calcium results in decreased expression of IL18RAP mRNA]
|
CTD |
PMID:18192897 |
|
NCBI chr 9:42,768,112...42,800,964
Ensembl chr 9:42,768,220...42,800,959
|
|
G
|
Il1b
|
interleukin 1 beta
|
decreases expression
|
EXP
|
Rosuvastatin Calcium results in decreased expression of IL1B mRNA
|
CTD |
PMID:15681303 |
|
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415
|
|
G
|
Kcnh2
|
potassium voltage-gated channel subfamily H member 2
|
decreases activity
|
ISO
|
Rosuvastatin Calcium results in decreased activity of KCNH2 protein
|
CTD |
PMID:28551711 |
|
NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:10,826,928...10,859,008
|
|
G
|
Kcnj15
|
potassium inwardly-rectifying channel, subfamily J, member 15
|
decreases expression
|
ISO
|
Rosuvastatin Calcium results in decreased expression of KCNJ15 mRNA
|
CTD |
PMID:18192897 |
|
NCBI chr11:34,577,397...34,621,725
Ensembl chr11:34,577,363...34,621,952
|
|
G
|
Kdr
|
kinase insert domain receptor
|
multiple interactions
|
ISO
|
Rosuvastatin Calcium inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of KDR protein]
|
CTD |
PMID:27097221 |
|
NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,217,871...32,261,018
|
|
G
|
Mb
|
myoglobin
|
affects expression
|
EXP
|
Rosuvastatin Calcium affects the expression of MB protein
|
CTD |
PMID:27815113 |
|
NCBI chr 7:110,640,511...110,647,742
Ensembl chr 7:108,759,904...108,767,383
|
|
G
|
Mstn
|
myostatin
|
increases expression
|
ISO
|
Rosuvastatin Calcium results in increased expression of MSTN protein
|
CTD |
PMID:33034787 |
|
NCBI chr 9:48,452,533...48,458,933
Ensembl chr 9:48,452,533...48,458,933
|
|
G
|
Nfe2l2
|
NFE2 like bZIP transcription factor 2
|
multiple interactions
|
EXP
|
Rosuvastatin Calcium inhibits the reaction [Isoproterenol results in decreased expression of NFE2L2 mRNA]
|
CTD |
PMID:32007421 PMID:35130744 |
|
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737
|
|
G
|
Nos2
|
nitric oxide synthase 2
|
increases expression multiple interactions
|
EXP
|
Rosuvastatin Calcium results in increased expression of NOS2 mRNA Rosuvastatin Calcium inhibits the reaction [Isoproterenol results in increased expression of NOS2 mRNA]
|
CTD |
PMID:21443142 PMID:32007421 PMID:35130744 |
|
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:63,815,308...63,851,210
|
|
G
|
Nos3
|
nitric oxide synthase 3
|
multiple interactions increases expression affects response to substance
|
ISO EXP
|
Rosuvastatin Calcium inhibits the reaction [CRP protein results in decreased expression of NOS3]; Rosuvastatin Calcium results in increased phosphorylation of and results in increased activity of NOS3 protein Rosuvastatin Calcium results in increased expression of NOS3 mRNA NOS3 protein affects the susceptibility to Rosuvastatin Calcium
|
CTD |
PMID:12354446 PMID:15681303 PMID:18162361 PMID:21562509 |
|
NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:10,793,834...10,814,166
|
|
G
|
Orm1
|
orosomucoid 1
|
multiple interactions decreases expression
|
ISO
|
Lipopolysaccharides inhibits the reaction [Rosuvastatin Calcium results in decreased expression of ORM1 mRNA]
|
CTD |
PMID:18192897 |
|
NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154
|
|
G
|
Pecam1
|
platelet and endothelial cell adhesion molecule 1
|
multiple interactions
|
ISO
|
Rosuvastatin Calcium inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PECAM1 protein]
|
CTD |
PMID:27097221 |
|
NCBI chr10:92,090,263...92,152,002
Ensembl chr10:91,590,521...91,652,116
|
|
G
|
Selp
|
selectin P
|
decreases expression
|
EXP
|
Rosuvastatin Calcium results in decreased expression of SELP mRNA
|
CTD |
PMID:15681303 |
|
NCBI chr13:79,009,379...79,044,994
Ensembl chr13:76,476,295...76,511,845
|
|
G
|
Serpine2
|
serpin family E member 2
|
multiple interactions
|
ISO
|
Rosuvastatin Calcium inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SERPINE2 protein]; Rosuvastatin Calcium inhibits the reaction [[TGFB1 protein co-treated with Serotonin] results in increased secretion of SERPINE2 protein]
|
CTD |
PMID:27097221 |
|
NCBI chr 9:88,573,138...88,637,252
Ensembl chr 9:81,124,804...81,188,826
|
|
G
|
Slco1a4
|
solute carrier organic anion transporter family, member 1a4
|
multiple interactions increases uptake decreases expression affects transport
|
EXP ISO
|
Fusidic Acid inhibits the reaction [SLCO1A4 protein results in increased uptake of Rosuvastatin Calcium] diosmetin inhibits the reaction [SLCO1A2 protein results in increased uptake of Rosuvastatin Calcium] Rosuvastatin Calcium results in decreased expression of SLCO1A4 protein SLCO1A4 protein affects the transport of Rosuvastatin Calcium
|
CTD |
PMID:19833843 PMID:24909372 PMID:26888941 PMID:28867436 |
|
NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573
|
|
G
|
Slco1b2
|
solute carrier organic anion transporter family member 1B2
|
multiple interactions increases uptake
|
EXP ISO
|
Fusidic Acid inhibits the reaction [SLCO1B2 protein results in increased uptake of Rosuvastatin Calcium] Fusidic Acid inhibits the reaction [SLCO1B3 protein results in increased uptake of Rosuvastatin Calcium]
|
CTD |
PMID:26888941 PMID:31299240 |
|
NCBI chr 4:174,551,463...174,619,988
Ensembl chr 4:174,551,480...174,619,981
|
|
G
|
Slco2b1
|
solute carrier organic anion transporter family, member 2b1
|
increases uptake multiple interactions
|
ISO
|
SLCO2B1 protein results in increased uptake of Rosuvastatin Calcium Rutin promotes the reaction [SLCO2B1 protein results in increased uptake of Rosuvastatin Calcium]
|
CTD |
PMID:24285294 |
|
NCBI chr 1:163,371,410...163,419,412
Ensembl chr 1:153,959,293...154,007,353
|
|
G
|
Sod1
|
superoxide dismutase 1
|
multiple interactions increases expression
|
EXP
|
[[[Rosuvastatin Calcium results in decreased expression of CYBB] co-treated with [Rosuvastatin Calcium results in decreased expression of CYBA]] co-treated with [Rosuvastatin Calcium results in increased expression of SOD1]] results in decreased abundance of Reactive Oxygen Species
|
CTD |
PMID:21562509 |
|
NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249
|
|
G
|
Tff1
|
trefoil factor 1
|
decreases expression
|
ISO
|
Rosuvastatin Calcium results in decreased expression of TFF1 mRNA
|
CTD |
PMID:32771489 |
|
NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
|
|
G
|
Tgfb1
|
transforming growth factor, beta 1
|
multiple interactions decreases expression
|
ISO EXP
|
Rosuvastatin Calcium inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]; Rosuvastatin Calcium inhibits the reaction [[TGFB1 protein co-treated with Serotonin] results in increased secretion of SERPINE2 protein] Rosuvastatin Calcium results in decreased expression of TGFB1 mRNA
|
CTD |
PMID:15681303 PMID:27097221 |
|
NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847
|
|
G
|
Tnf
|
tumor necrosis factor
|
decreases expression multiple interactions
|
EXP
|
Rosuvastatin Calcium results in decreased expression of TNF mRNA Rosuvastatin Calcium inhibits the reaction [Isoproterenol results in increased expression of TNF protein]
|
CTD |
PMID:15681303 PMID:32007421 PMID:35130744 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
|
|
G
|
Tnni3
|
troponin I3, cardiac type
|
multiple interactions
|
EXP
|
Rosuvastatin Calcium inhibits the reaction [Isoproterenol results in increased expression of TNNI3 protein]
|
CTD |
PMID:32007421 PMID:35130744 |
|
NCBI chr 1:69,299,900...69,303,582
Ensembl chr 1:69,299,900...69,303,580
|
|
G
|
Vnn3
|
vanin 3
|
decreases expression
|
ISO
|
Rosuvastatin Calcium results in decreased expression of VNN3P mRNA
|
CTD |
PMID:18192897 |
|
NCBI chr 1:21,571,364...21,583,626
Ensembl chr 1:21,571,364...21,583,626
|
|
G
|
Wt1
|
WT1 transcription factor
|
increases expression
|
EXP
|
Rosuvastatin Calcium results in increased expression of WT1 mRNA
|
CTD |
PMID:21443142 |
|
NCBI chr 3:112,019,721...112,068,454
Ensembl chr 3:91,567,001...91,613,643
|
|
|
G
|
Acox1
|
acyl-CoA oxidase 1
|
increases expression
|
ISO
|
Sodium Acetate results in increased expression of ACOX1 mRNA
|
CTD |
PMID:36156098 |
|
NCBI chr10:101,905,083...101,930,136
Ensembl chr10:101,406,197...101,431,232
|
|
G
|
Acss1
|
acyl-CoA synthetase short-chain family member 1
|
increases expression
|
ISO
|
Sodium Acetate results in increased expression of ACSS1 mRNA
|
CTD |
PMID:36156098 |
|
NCBI chr 3:159,910,809...159,960,748
Ensembl chr 3:139,450,383...139,500,325
|
|
G
|
Acss2
|
acyl-CoA synthetase short-chain family member 2
|
increases expression
|
ISO
|
Sodium Acetate results in increased expression of ACSS2 mRNA
|
CTD |
PMID:36156098 |
|
NCBI chr 3:164,464,124...164,507,607
Ensembl chr 3:144,004,336...144,059,675
|
|
G
|
Ada
|
adenosine deaminase
|
multiple interactions
|
EXP
|
Sodium Acetate inhibits the reaction [Nicotine results in increased activity of ADA protein]
|
CTD |
PMID:31857090 |
|
NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:152,398,747...152,447,088
|
|
G
|
Apob
|
apolipoprotein B
|
multiple interactions
|
ISO
|
[Sodium Acetate co-treated with acetic anhydride] results in increased acetylation of APOB protein
|
CTD |
PMID:11304478 |
|
NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
|
|
G
|
Casp3
|
caspase 3
|
multiple interactions
|
ISO EXP
|
Sodium Acetate inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]
|
CTD |
PMID:36372261 |
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648
|
|
G
|
Casp7
|
caspase 7
|
multiple interactions
|
ISO
|
Sodium Acetate inhibits the reaction [Cisplatin results in increased cleavage of CASP7 protein]
|
CTD |
PMID:36372261 |
|
NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:255,437,172...255,476,729
|
|
G
|
Cat
|
catalase
|
multiple interactions
|
ISO EXP
|
Sodium Acetate inhibits the reaction [Cisplatin results in decreased expression of CAT protein]
|
CTD |
PMID:36372261 |
|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478
|
|
G
|
Cyp1a1
|
cytochrome P450, family 1, subfamily a, polypeptide 1
|
multiple interactions
|
ISO
|
Sodium Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] Sodium Acetate promotes the reaction [biochanin A results in increased expression of CYP1A1 mRNA]; Sodium Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
|
CTD |
PMID:31621310 |
|
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125
|
|
G
|
Cyp1b1
|
cytochrome P450, family 1, subfamily b, polypeptide 1
|
multiple interactions
|
ISO
|
Sodium Acetate promotes the reaction [biochanin A results in increased expression of CYP1B1 mRNA]; Sodium Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]
|
CTD |
PMID:31621310 |
|
NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:15,342,344...15,350,917
|
|
G
|
Ggt1
|
gamma-glutamyltransferase 1
|
multiple interactions
|
EXP
|
Sodium Acetate inhibits the reaction [Nicotine results in increased activity of GGT1 protein]
|
CTD |
PMID:31857090 |
|
NCBI chr20:13,074,141...13,103,551
Ensembl chr20:13,074,700...13,108,442
|
|
G
|
Ifng
|
interferon gamma
|
multiple interactions
|
ISO
|
[Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in increased expression of IFNG mRNA]
|
CTD |
PMID:37269894 |
|
NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375
|
|
G
|
Ikbkb
|
inhibitor of nuclear factor kappa B kinase subunit beta
|
multiple interactions
|
ISO
|
[Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in increased expression of IKBKB mRNA]; [Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in increased expression of IKBKB protein]
|
CTD |
PMID:37269894 |
|
NCBI chr16:76,021,968...76,075,717
Ensembl chr16:69,319,554...69,373,250
|
|
G
|
Il2
|
interleukin 2
|
multiple interactions
|
ISO
|
Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of IL2 protein]
|
CTD |
PMID:17615583 |
|
NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:120,004,862...120,009,566
|
|
G
|
Il6
|
interleukin 6
|
multiple interactions
|
ISO
|
[Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in increased expression of IL6 mRNA]
|
CTD |
PMID:37269894 |
|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178
|
|
G
|
Ins1
|
insulin 1
|
multiple interactions
|
EXP
|
Sodium Acetate inhibits the reaction [Nicotine results in increased expression of INS1 protein]
|
CTD |
PMID:31857090 |
|
NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:251,244,973...251,245,536
|
|
G
|
Kpnb1
|
karyopherin subunit beta 1
|
multiple interactions
|
ISO
|
Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [NFATC2 protein binds to KPNB1 protein]]
|
CTD |
PMID:17615583 |
|
NCBI chr10:82,145,662...82,174,437
Ensembl chr10:82,145,420...82,174,605
|
|
G
|
Myd88
|
MYD88, innate immune signal transduction adaptor
|
multiple interactions
|
ISO
|
[Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in increased expression of MYD88 mRNA]
|
CTD |
PMID:37269894 |
|
NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415
|
|
G
|
Nat2
|
N-acetyltransferase 2
|
increases expression
|
ISO
|
Sodium Acetate results in increased expression of NAT2 mRNA
|
CTD |
PMID:36156098 |
|
NCBI chr16:26,974,874...27,005,191
Ensembl chr16:22,208,194...22,238,520
|
|
G
|
Nfatc2
|
nuclear factor of activated T-cells 2
|
multiple interactions
|
ISO
|
Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] affects the localization of NFATC2 protein]; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [NFATC2 protein binds to KPNB1 protein]]; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of NFATC2 protein]
|
CTD |
PMID:17615583 |
|
NCBI chr 3:177,615,189...177,747,493
Ensembl chr 3:157,198,872...157,328,325
|
|
G
|
Nfkbia
|
NFKB inhibitor alpha
|
multiple interactions
|
ISO
|
[Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in decreased expression of NFKBIA protein]
|
CTD |
PMID:37269894 |
|
NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941
|
|
G
|
Pck1
|
phosphoenolpyruvate carboxykinase 1
|
increases expression
|
ISO
|
Sodium Acetate results in increased expression of PCK1 mRNA
|
CTD |
PMID:36156098 |
|
NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:161,930,256...161,936,191
|
|
G
|
Rela
|
RELA proto-oncogene, NF-kB subunit
|
multiple interactions
|
ISO
|
[Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in increased expression of and results in increased phosphorylation of RELA protein]; [Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in increased expression of RELA mRNA]
|
CTD |
PMID:37269894 |
|
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484
|
|
G
|
Sod2
|
superoxide dismutase 2
|
multiple interactions
|
ISO EXP
|
Sodium Acetate inhibits the reaction [Cisplatin results in decreased expression of SOD2 protein]
|
CTD |
PMID:36372261 |
|
NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189
|
|
G
|
Tgfb1
|
transforming growth factor, beta 1
|
multiple interactions
|
ISO
|
[Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in increased expression of TGFB1 mRNA]
|
CTD |
PMID:37269894 |
|
NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847
|
|
G
|
Tlr2
|
toll-like receptor 2
|
multiple interactions
|
ISO
|
[Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in increased expression of TLR2 mRNA]; [Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in increased expression of TLR2 protein]
|
CTD |
PMID:37269894 |
|
NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630
|
|
G
|
Tlr4
|
toll-like receptor 4
|
multiple interactions
|
ISO
|
[Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in increased expression of TLR4 mRNA]; [Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in increased expression of TLR4 protein]
|
CTD |
PMID:37269894 |
|
NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628
|
|
G
|
Tnf
|
tumor necrosis factor
|
multiple interactions
|
ISO
|
[Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in increased expression of TNF mRNA]
|
CTD |
PMID:37269894 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
|
|
G
|
Ugt1a1
|
UDP glucuronosyltransferase family 1 member A1
|
multiple interactions
|
ISO
|
Sodium Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of UGT1A1 mRNA]
|
CTD |
PMID:31621310 |
|
NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:88,713,184...88,808,465
|
|
G
|
Xdh
|
xanthine dehydrogenase
|
multiple interactions
|
EXP
|
Sodium Acetate inhibits the reaction [Nicotine results in increased activity of XDH protein]
|
CTD |
PMID:31857090 |
|
NCBI chr 6:27,282,319...27,344,022
Ensembl chr 6:21,530,113...21,592,268
|
|
|
G
|
Ache
|
acetylcholinesterase
|
multiple interactions increases activity
|
EXP
|
Ascorbic Acid inhibits the reaction [Sodium Benzoate results in increased activity of ACHE protein]
|
CTD |
PMID:35187746 |
|
NCBI chr12:25,042,882...25,050,608
Ensembl chr12:19,407,360...19,413,651
|
|
G
|
Acta2
|
actin alpha 2, smooth muscle
|
multiple interactions
|
ISO
|
Sodium Benzoate inhibits the reaction [arsenite results in increased expression of ACTA2 protein]
|
CTD |
PMID:38703806 |
|
NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:231,746,548...231,759,554
|
|
G
|
Ahr
|
aryl hydrocarbon receptor
|
multiple interactions
|
ISO
|
Sodium Benzoate inhibits the reaction [[DAO protein results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]
|
CTD |
PMID:19860415 |
|
NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568
|
|
G
|
Camk2a
|
calcium/calmodulin-dependent protein kinase II alpha
|
multiple interactions
|
EXP
|
Sodium Benzoate promotes the reaction [Cocaine results in increased phosphorylation of and results in increased activity of CAMK2A protein]
|
CTD |
PMID:17609678 |
|
NCBI chr18:56,648,779...56,711,505
Ensembl chr18:54,378,784...54,438,994
|
|
G
|
Casp3
|
caspase 3
|
multiple interactions increases expression increases activity
|
ISO EXP
|
Sodium Benzoate inhibits the reaction [Asbestos, Amosite results in increased activity of CASP3 protein] Sodium Benzoate results in increased expression of CASP3 protein Ascorbic Acid inhibits the reaction [Sodium Benzoate results in increased expression of CASP3 protein] Sodium Benzoate results in increased activity of CASP3 protein
|
CTD |
PMID:11329530 PMID:32911041 PMID:35187746 |
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648
|
|
G
|
Casp9
|
caspase 9
|
multiple interactions
|
ISO
|
Sodium Benzoate inhibits the reaction [Asbestos, Amosite results in increased activity of CASP9 protein]
|
CTD |
PMID:12540492 |
|
Ensembl chr 5:154,109,046...154,126,626
|
|
G
|
Cat
|
catalase
|
decreases activity multiple interactions
|
EXP
|
Sodium Benzoate results in decreased activity of CAT protein Ascorbic Acid inhibits the reaction [Sodium Benzoate results in decreased activity of CAT protein]
|
CTD |
PMID:32911041 PMID:35187746 |
|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478
|
|
G
|
Col1a1
|
collagen type I alpha 1 chain
|
multiple interactions
|
ISO
|
Sodium Benzoate inhibits the reaction [arsenite results in increased expression of COL1A1 protein]
|
CTD |
PMID:38703806 |
|
NCBI chr10:80,380,458...80,397,461
Ensembl chr10:79,883,622...79,900,624
|
|
G
|
Col3a1
|
collagen type III alpha 1 chain
|
multiple interactions
|
ISO
|
Sodium Benzoate inhibits the reaction [arsenite results in increased expression of COL3A1 protein]
|
CTD |
PMID:38703806 |
|
NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:47,374,593...47,410,547
|
|
G
|
Cps1
|
carbamoyl-phosphate synthase 1
|
multiple interactions
|
ISO
|
Sodium Benzoate inhibits the reaction [arsenite results in increased expression of CPS1 protein]
|
CTD |
PMID:38703806 |
|
NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033
|
|
G
|
Cyp1a1
|
cytochrome P450, family 1, subfamily a, polypeptide 1
|
multiple interactions
|
ISO
|
Sodium Benzoate inhibits the reaction [[DAO protein results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]
|
CTD |
PMID:19860415 |
|
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125
|
|
G
|
Dao
|
D-amino-acid oxidase
|
multiple interactions decreases activity
|
ISO EXP
|
Sodium Benzoate inhibits the reaction [[DAO protein results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA] Sodium Benzoate results in decreased activity of DAO protein
|
CTD |
PMID:19860415 PMID:20952482 |
|
NCBI chr12:42,592,342...42,613,046
Ensembl chr12:42,592,343...42,612,741
|
|
G
|
Esr1
|
estrogen receptor 1
|
decreases activity
|
ISO
|
Sodium Benzoate results in decreased activity of ESR1 protein
|
CTD |
PMID:22562034 |
|
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002
|
|
G
|
Fshb
|
follicle stimulating hormone subunit beta
|
increases expression
|
EXP
|
Sodium Benzoate results in increased expression of FSHB protein
|
CTD |
PMID:32911041 |
|
NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:93,548,560...93,552,370
|
|
G
|
Ifng
|
interferon gamma
|
multiple interactions
|
ISO EXP
|
Sodium Benzoate inhibits the reaction [Lipopolysaccharides results in increased secretion of IFNG protein] [Food Preservatives results in increased abundance of Sodium Benzoate] which results in increased expression of IFNG mRNA
|
CTD |
PMID:26706697 PMID:32179172 |
|
NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375
|
|
G
|
Il10
|
interleukin 10
|
multiple interactions
|
EXP
|
[Food Preservatives results in increased abundance of Sodium Benzoate] which results in increased expression of IL10 mRNA
|
CTD |
PMID:32179172 |
|
NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313
|
|
G
|
Il1b
|
interleukin 1 beta
|
multiple interactions
|
EXP
|
[Food Preservatives results in increased abundance of Sodium Benzoate] which results in increased expression of IL1B mRNA
|
CTD |
PMID:32179172 |
|
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415
|
|
G
|
Il6
|
interleukin 6
|
multiple interactions increases expression
|
ISO EXP
|
Sodium Benzoate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] [Food Preservatives results in increased abundance of Sodium Benzoate] which results in increased expression of IL6 mRNA Sodium Benzoate results in increased expression of IL6 protein
|
CTD |
PMID:26706697 PMID:32179172 PMID:32911041 |
|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178
|
|
G
|
Lhb
|
luteinizing hormone subunit beta
|
increases expression
|
EXP
|
Sodium Benzoate results in increased expression of LHB protein
|
CTD |
PMID:32911041 |
|
NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
|
|
G
|
Msr1
|
macrophage scavenger receptor 1
|
multiple interactions
|
ISO
|
Sodium Benzoate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA alternative form]; Sodium Benzoate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]
|
CTD |
PMID:9614211 |
|
NCBI chr16:52,717,775...52,803,602
Ensembl chr16:52,717,732...52,799,676
|
|
G
|
Otc
|
ornithine transcarbamylase
|
multiple interactions
|
ISO
|
Sodium Benzoate affects the reaction [OTC gene mutant form affects the abundance of Hydroxyindoleacetic Acid]; Sodium Benzoate affects the reaction [OTC gene mutant form affects the metabolism of Glycine]; Sodium Benzoate affects the reaction [OTC gene mutant form affects the metabolism of Serotonin]; Sodium Benzoate affects the reaction [OTC gene mutant form results in increased abundance of Ammonium Compounds]
|
CTD |
PMID:3091026 PMID:3374991 |
|
NCBI chr X:12,453,834...12,529,954
Ensembl chr X:12,453,834...12,566,918
|
|
G
|
Tfam
|
transcription factor A, mitochondrial
|
increases expression
|
EXP
|
Sodium Benzoate results in increased expression of TFAM protein
|
CTD |
PMID:32911041 |
|
NCBI chr20:17,355,373...17,367,422
Ensembl chr20:17,356,197...17,368,292
|
|
G
|
Tnf
|
tumor necrosis factor
|
multiple interactions increases expression
|
ISO EXP
|
Sodium Benzoate inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] [Food Preservatives results in increased abundance of Sodium Benzoate] which results in increased expression of TNF mRNA; Ascorbic Acid inhibits the reaction [Sodium Benzoate results in increased expression of TNF protein]
|
CTD |
PMID:26706697 PMID:32179172 PMID:32911041 PMID:35187746 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
|
|
G
|
Tp53
|
tumor protein p53
|
multiple interactions increases expression
|
ISO EXP
|
Sodium Benzoate inhibits the reaction [Asbestos, Amosite results in increased expression of TP53 mRNA] Sodium Benzoate results in increased expression of TP53 protein
|
CTD |
PMID:16357363 PMID:32911041 |
|
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524
|
|
G
|
Ucp2
|
uncoupling protein 2
|
increases expression
|
EXP
|
Sodium Benzoate results in increased expression of UCP2 protein
|
CTD |
PMID:32911041 |
|
NCBI chr 1:164,251,373...164,257,742
Ensembl chr 1:154,839,209...154,845,611
|
|
G
|
Vim
|
vimentin
|
multiple interactions
|
ISO
|
Sodium Benzoate inhibits the reaction [arsenite results in increased expression of VIM protein]
|
CTD |
PMID:38703806 |
|
NCBI chr17:81,577,261...81,585,746
Ensembl chr17:76,668,647...76,677,187
|
|
G
|
Xdh
|
xanthine dehydrogenase
|
increases activity
|
EXP
|
Sodium Benzoate results in increased activity of XDH protein
|
CTD |
PMID:32911041 |
|
NCBI chr 6:27,282,319...27,344,022
Ensembl chr 6:21,530,113...21,592,268
|
|
|
G
|
Alb
|
albumin
|
multiple interactions
|
EXP
|
[cocoa butter co-treated with Sodium Cholate co-treated with Cholesterol] results in increased expression of ALB protein
|
CTD |
PMID:26606054 |
|
NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,607,381...17,622,836
|
|
G
|
Alpl
|
alkaline phosphatase, biomineralization associated
|
multiple interactions
|
ISO
|
[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased secretion of ALPL protein; MET gene mutant form promotes the reaction [[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased secretion of ALPL protein]
|
CTD |
PMID:27394961 |
|
NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:149,951,409...150,006,446
|
|
G
|
Bax
|
BCL2 associated X, apoptosis regulator
|
multiple interactions
|
ISO
|
[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased expression of BAX protein
|
CTD |
PMID:27394961 |
|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368
|
|
G
|
Bcl2
|
BCL2, apoptosis regulator
|
multiple interactions
|
ISO
|
[Cholesterol, Dietary co-treated with Sodium Cholate] results in decreased expression of BCL2 protein
|
CTD |
PMID:27394961 |
|
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
|
|
G
|
Casp3
|
caspase 3
|
multiple interactions
|
ISO
|
[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased cleavage of CASP3 protein; MET gene mutant form promotes the reaction [[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased cleavage of CASP3 protein]
|
CTD |
PMID:27394961 |
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648
|
|
G
|
Ccl2
|
C-C motif chemokine ligand 2
|
multiple interactions
|
ISO EXP
|
[eicosapentaenoic acid ethyl ester co-treated with Sodium Cholate co-treated with Dietary Fats] results in increased expression of CCL2 mRNA [cocoa butter co-treated with Sodium Cholate co-treated with Cholesterol] results in increased expression of CCL2 mRNA
|
CTD |
PMID:23665937 PMID:26606054 |
|
NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,005,424...67,007,226
|
|
G
|
Ccl5
|
C-C motif chemokine ligand 5
|
multiple interactions
|
ISO
|
[eicosapentaenoic acid ethyl ester co-treated with Sodium Cholate co-treated with Dietary Fats] results in increased expression of CCL5 mRNA
|
CTD |
PMID:23665937 |
|
NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,322,829...68,327,377
|
|
G
|
Ccnd1
|
cyclin D1
|
multiple interactions
|
ISO
|
[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased expression of CCND1 protein; MET gene mutant form inhibits the reaction [[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased expression of CCND1 protein]
|
CTD |
PMID:27394961 |
|
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602
|
|
G
|
Ces1d
|
carboxylesterase 1D
|
increases expression
|
ISO
|
Sodium Cholate results in increased expression of CES1 mRNA
|
CTD |
PMID:9565681 |
|
NCBI chr19:30,046,494...30,085,039
Ensembl chr19:13,796,623...13,912,035
|
|
G
|
Cst3
|
cystatin C
|
multiple interactions
|
EXP
|
[cocoa butter co-treated with Sodium Cholate co-treated with Cholesterol] results in increased expression of CST3 protein
|
CTD |
PMID:26606054 |
|
NCBI chr 3:156,790,061...156,794,116
Ensembl chr 3:136,336,920...136,340,822
|
|
G
|
Cybb
|
cytochrome b-245 beta chain
|
multiple interactions
|
EXP
|
[cocoa butter co-treated with Sodium Cholate co-treated with Cholesterol] results in increased expression of CYBB mRNA
|
CTD |
PMID:26606054 |
|
NCBI chr X:16,030,596...16,065,065
Ensembl chr X:13,359,430...13,392,586
|
|
G
|
Cyp3a2
|
cytochrome P450, family 3, subfamily a, polypeptide 2
|
multiple interactions
|
EXP ISO
|
[1,2-dilauroylphosphatidylcholine co-treated with 1,2-oleoylphosphatidylcholine co-treated with Phosphatidylserines co-treated with Sodium Cholate] results in increased activity of CYP3A2 protein [1,2-dilauroylphosphatidylcholine co-treated with 1,2-oleoylphosphatidylcholine co-treated with Phosphatidylserines co-treated with Sodium Cholate] results in increased activity of CYP3A4 protein
|
CTD |
PMID:1627548 |
|
NCBI chr12:14,321,771...14,343,886
Ensembl chr12:9,015,383...9,285,008
|
|
G
|
Cyp7a1
|
cytochrome P450 family 7 subfamily A member 1
|
multiple interactions
|
ISO
|
[Sodium Cholate co-treated with Dietary Fats] results in decreased expression of CYP7A1 mRNA
|
CTD |
PMID:23665937 |
|
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
|
|
G
|
Fabp1
|
fatty acid binding protein 1
|
multiple interactions
|
EXP
|
[cocoa butter co-treated with Sodium Cholate co-treated with Cholesterol] results in increased expression of FABP1 protein
|
CTD |
PMID:26606054 |
|
NCBI chr 4:104,744,302...104,753,119
Ensembl chr 4:103,191,006...103,194,788
|
|
G
|
Gclc
|
glutamate-cysteine ligase, catalytic subunit
|
multiple interactions
|
ISO
|
[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased expression of GCLC protein; MET gene mutant form inhibits the reaction [[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased expression of GCLC protein]
|
CTD |
PMID:27394961 |
|
NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:78,630,127...78,668,544
|
|
G
|
Gpx2
|
glutathione peroxidase 2
|
multiple interactions
|
EXP
|
[cocoa butter co-treated with Sodium Cholate co-treated with Cholesterol] results in increased expression of GPX2 mRNA
|
CTD |
PMID:26606054 |
|
NCBI chr 6:101,226,745...101,230,033
Ensembl chr 6:95,493,589...95,496,877
|
|
G
|
Havcr1
|
hepatitis A virus cellular receptor 1
|
multiple interactions
|
EXP
|
[cocoa butter co-treated with Sodium Cholate co-treated with Cholesterol] results in increased expression of HAVCR1 mRNA
|
CTD |
PMID:26606054 |
|
NCBI chr10:31,619,914...31,652,955
Ensembl chr10:31,119,088...31,151,698
|
|
G
|
Hif1a
|
hypoxia inducible factor 1 subunit alpha
|
multiple interactions
|
EXP
|
[cocoa butter co-treated with Sodium Cholate co-treated with Cholesterol] results in increased expression of HIF1A mRNA
|
CTD |
PMID:26606054 |
|
NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:92,624,390...92,669,261
|
|
G
|
Hmgcr
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
multiple interactions
|
ISO
|
[Sodium Cholate co-treated with Dietary Fats] results in decreased expression of HMGCR mRNA
|
CTD |
PMID:23665937 |
|
NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:27,997,525...28,019,703
|
|
G
|
Hmox1
|
heme oxygenase 1
|
multiple interactions
|
EXP
|
[cocoa butter co-treated with Sodium Cholate co-treated with Cholesterol] results in increased expression of HMOX1 mRNA
|
CTD |
PMID:26606054 |
|
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079
|
|
G
|
Icam1
|
intercellular adhesion molecule 1
|
multiple interactions
|
ISO
|
[eicosapentaenoic acid ethyl ester co-treated with Sodium Cholate co-treated with Dietary Fats] results in increased expression of ICAM1 mRNA
|
CTD |
PMID:23665937 |
|
NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:19,553,645...19,565,438
|
|
G
|
Il1b
|
interleukin 1 beta
|
multiple interactions
|
ISO EXP
|
[eicosapentaenoic acid ethyl ester co-treated with Sodium Cholate co-treated with Dietary Fats] results in increased expression of IL1B mRNA [cocoa butter co-treated with Sodium Cholate co-treated with Cholesterol] results in increased expression of IL1B mRNA
|
CTD |
PMID:23665937 PMID:26606054 |
|
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415
|
|
G
|
Mapk1
|
mitogen activated protein kinase 1
|
multiple interactions
|
ISO
|
[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased phosphorylation of MAPK1 protein; MET gene mutant form inhibits the reaction [[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased phosphorylation of MAPK1 protein]
|
CTD |
PMID:27394961 |
|
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616
|
|
G
|
Mapk3
|
mitogen activated protein kinase 3
|
multiple interactions
|
ISO
|
[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased phosphorylation of MAPK3 protein; MET gene mutant form inhibits the reaction [[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased phosphorylation of MAPK3 protein]
|
CTD |
PMID:27394961 |
|
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863
|
|
G
|
Met
|
MET proto-oncogene, receptor tyrosine kinase
|
multiple interactions
|
ISO
|
MET gene mutant form affects the susceptibility to [Cholesterol, Dietary co-treated with Sodium Cholate]; MET gene mutant form inhibits the reaction [[Cholesterol, Dietary co-treated with Sodium Cholate] results in decreased expression of TRP53 protein]; MET gene mutant form inhibits the reaction [[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased expression of CCND1 protein]; MET gene mutant form inhibits the reaction [[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased expression of GCLC protein]; MET gene mutant form inhibits the reaction [[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased expression of NFE2L2 protein]; MET gene mutant form inhibits the reaction [[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased expression of NR1I3 protein]; MET gene mutant form inhibits the reaction [[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased expression of RARA protein]; MET gene mutant form inhibits the reaction [[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased phosphorylation of MAPK1 protein]; MET gene mutant form inhibits the reaction [[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased phosphorylation of MAPK3 protein]; MET gene mutant form promotes the reaction [[[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased oxidation of Lipids] which results in increased abundance of Thiobarbituric Acid Reactive Substances]; MET gene mutant form promotes the reaction [[Cholesterol, Dietary co-treated with Sodium Cholate] results in decreased expression of PPARA protein]; MET gene mutant form promotes the reaction [[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased abundance of Triglycerides]; MET gene mutant form promotes the reaction [[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased cleavage of CASP3 protein]; MET gene mutant form promotes the reaction [[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased cleavage of SREBF1 protein]; MET gene mutant form promotes the reaction [[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased expression of NR1H3 protein]; MET gene mutant form promotes the reaction [[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased oxidation of Glutathione]; MET gene mutant form promotes the reaction [[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased secretion of ALPL protein]; MET gene mutant form promotes the reaction [[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased secretion of Bile Acids and Salts]; MET gene mutant form promotes the reaction [[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased uptake of and results in increased oxidation of Lipids]
|
CTD |
PMID:27394961 |
|
NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:45,790,791...45,897,876
|
|
G
|
Naglu
|
N-acetyl-alpha-glucosaminidase
|
multiple interactions
|
EXP
|
[cocoa butter co-treated with Sodium Cholate co-treated with Cholesterol] results in increased expression of NAGLU protein
|
CTD |
PMID:26606054 |
|
NCBI chr10:86,501,864...86,509,333
Ensembl chr10:86,001,566...86,008,972
|
|
G
|
Nfe2l2
|
NFE2 like bZIP transcription factor 2
|
multiple interactions
|
ISO
|
[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased expression of NFE2L2 protein; MET gene mutant form inhibits the reaction [[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased expression of NFE2L2 protein]
|
CTD |
PMID:27394961 |
|
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737
|
|
G
|
Nr1h3
|
nuclear receptor subfamily 1, group H, member 3
|
multiple interactions
|
ISO
|
[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased expression of NR1H3 protein; MET gene mutant form promotes the reaction [[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased expression of NR1H3 protein]
|
CTD |
PMID:27394961 |
|
NCBI chr 3:97,614,616...97,632,053
Ensembl chr 3:77,158,808...77,168,722
|
|
G
|
Nr1i3
|
nuclear receptor subfamily 1, group I, member 3
|
multiple interactions
|
ISO
|
[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased expression of NR1I3 protein; MET gene mutant form inhibits the reaction [[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased expression of NR1I3 protein]
|
CTD |
PMID:27394961 |
|
NCBI chr13:86,165,327...86,170,362
Ensembl chr13:83,632,899...83,637,906
|
|
G
|
Ppara
|
peroxisome proliferator activated receptor alpha
|
multiple interactions
|
ISO
|
[Cholesterol, Dietary co-treated with Sodium Cholate] results in decreased expression of PPARA protein; MET gene mutant form promotes the reaction [[Cholesterol, Dietary co-treated with Sodium Cholate] results in decreased expression of PPARA protein]
|
CTD |
PMID:27394961 |
|
NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346
|
|
G
|
Rara
|
retinoic acid receptor, alpha
|
multiple interactions
|
ISO
|
[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased expression of RARA protein; MET gene mutant form inhibits the reaction [[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased expression of RARA protein]
|
CTD |
PMID:27394961 |
|
NCBI chr10:84,379,780...84,424,371
Ensembl chr10:83,893,384...83,928,142
|
|
G
|
S100a8
|
S100 calcium binding protein A8
|
multiple interactions
|
EXP
|
[cocoa butter co-treated with Sodium Cholate co-treated with Cholesterol] results in increased expression of S100A8 mRNA
|
CTD |
PMID:26606054 |
|
NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
|
|
G
|
Scd
|
stearoyl-CoA desaturase
|
multiple interactions
|
ISO
|
[Sodium Cholate co-treated with Dietary Fats] results in increased expression of SCD1 mRNA; eicosapentaenoic acid ethyl ester inhibits the reaction [[Sodium Cholate co-treated with Dietary Fats] results in increased expression of SCD1 mRNA]
|
CTD |
PMID:23665937 |
|
NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:243,269,747...243,282,562
|
|
G
|
Soat2
|
sterol O-acyltransferase 2
|
multiple interactions
|
ISO
|
[Sodium Cholate co-treated with Dietary Fats] results in increased expression of SOAT2 mRNA; eicosapentaenoic acid ethyl ester inhibits the reaction [[Sodium Cholate co-treated with Dietary Fats] results in increased expression of SOAT2 mRNA]
|
CTD |
PMID:23665937 |
|
NCBI chr 7:133,281,818...133,294,915
Ensembl chr 7:133,281,818...133,294,915
|
|
G
|
Sod2
|
superoxide dismutase 2
|
multiple interactions
|
ISO
|
[Sodium Cholate co-treated with Deoxycholic Acid co-treated with Glycocholic Acid co-treated with Taurocholic Acid] results in decreased expression of and results in decreased activity of SOD2 protein; [Sodium Cholate co-treated with Deoxycholic Acid co-treated with Glycocholic Acid co-treated with Taurocholic Acid] results in increased expression of and results in decreased activity of SOD2 protein; Curcumin analog inhibits the reaction [[Sodium Cholate co-treated with Deoxycholic Acid co-treated with Glycocholic Acid co-treated with Taurocholic Acid] results in decreased expression of and results in decreased activity of SOD2 protein]; Curcumin analog inhibits the reaction [[Sodium Cholate co-treated with Deoxycholic Acid co-treated with Glycocholic Acid co-treated with Taurocholic Acid] results in increased expression of and results in decreased activity of SOD2 protein]; Curcumin analog promotes the reaction [[Sodium Cholate co-treated with Deoxycholic Acid co-treated with Glycocholic Acid co-treated with Taurocholic Acid] results in increased expression of SOD2 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [[Sodium Cholate co-treated with Deoxycholic Acid co-treated with Glycocholic Acid co-treated with Taurocholic Acid] results in decreased expression of and results in decreased activity of SOD2 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin promotes the reaction [[Sodium Cholate co-treated with Deoxycholic Acid co-treated with Glycocholic Acid co-treated with Taurocholic Acid] results in increased expression of SOD2 protein]; Plant Extracts inhibits the reaction [[Sodium Cholate co-treated with Deoxycholic Acid co-treated with Glycocholic Acid co-treated with Taurocholic Acid] results in decreased expression of and results in decreased activity of SOD2 protein]; Plant Extracts inhibits the reaction [[Sodium Cholate co-treated with Deoxycholic Acid co-treated with Glycocholic Acid co-treated with Taurocholic Acid] results in increased expression of and results in decreased activity of SOD2 protein]
|
CTD |
PMID:22316666 |
|
NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189
|
|
G
|
Spmip11
|
sperm microtubule inner protein 11
|
multiple interactions
|
EXP
|
[cocoa butter co-treated with Sodium Cholate co-treated with Cholesterol] results in decreased expression of NPHS1 mRNA
|
CTD |
PMID:26606054 |
|
NCBI chr 7:129,720,950...129,742,485
Ensembl chr 7:129,720,950...129,742,485
|
|
G
|
Srebf1
|
sterol regulatory element binding transcription factor 1
|
multiple interactions
|
ISO
|
[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased cleavage of SREBF1 protein; MET gene mutant form promotes the reaction [[Cholesterol, Dietary co-treated with Sodium Cholate] results in increased cleavage of SREBF1 protein]
|
CTD |
PMID:27394961 |
|
NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,007,637...45,029,650
|
|
G
|
Tgfb1
|
transforming growth factor, beta 1
|
multiple interactions
|
EXP
|
[cocoa butter co-treated with Sodium Cholate co-treated with Cholesterol] results in increased expression of TGFB1 mRNA
|
CTD |
PMID:26606054 |
|
NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847
|
|
G
|
Tlr4
|
toll-like receptor 4
|
multiple interactions
|
EXP
|
[cocoa butter co-treated with Sodium Cholate co-treated with Cholesterol] results in increased expression of TLR4 mRNA
|
CTD |
PMID:26606054 |
|
NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628
|
|
G
|
Tnf
|
tumor necrosis factor
|
multiple interactions
|
EXP
|
[cocoa butter co-treated with Sodium Cholate co-treated with Cholesterol] results in increased expression of TNF mRNA
|
CTD |
PMID:26606054 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
|
|
G
|
Tp53
|
tumor protein p53
|
multiple interactions
|
ISO
|
[Cholesterol, Dietary co-treated with Sodium Cholate] results in decreased expression of TRP53 protein; MET gene mutant form inhibits the reaction [[Cholesterol, Dietary co-treated with Sodium Cholate] results in decreased expression of TRP53 protein]
|
CTD |
PMID:27394961 |
|
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524
|
|
G
|
Vcam1
|
vascular cell adhesion molecule 1
|
multiple interactions
|
EXP
|
[cocoa butter co-treated with Sodium Cholate co-treated with Cholesterol] results in increased expression of VCAM1 mRNA
|
CTD |
PMID:26606054 |
|
NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:204,038,114...204,057,958
|
|
|
G
|
Bax
|
BCL2 associated X, apoptosis regulator
|
multiple interactions
|
ISO
|
sodium propionate inhibits the reaction [Ethanol results in increased expression of BAX mRNA]
|
CTD |
PMID:35639301 |
|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368
|
|
G
|
Casp3
|
caspase 3
|
multiple interactions
|
ISO
|
sodium propionate inhibits the reaction [Ethanol results in increased expression of and results in increased cleavage of CASP3 mRNA]
|
CTD |
PMID:35639301 |
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648
|
|
G
|
Casp8
|
caspase 8
|
multiple interactions
|
ISO
|
sodium propionate inhibits the reaction [Ethanol results in increased expression of CASP8 mRNA]
|
CTD |
PMID:35639301 |
|
NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:60,264,075...60,312,542
|
|
G
|
Cldn1
|
claudin 1
|
multiple interactions
|
ISO
|
sodium propionate inhibits the reaction [Ethanol results in decreased expression of CLDN1 protein]
|
CTD |
PMID:35639301 |
|
NCBI chr11:87,926,376...87,941,533
Ensembl chr11:74,421,569...74,436,724
|
|
G
|
Cyp1a1
|
cytochrome P450, family 1, subfamily a, polypeptide 1
|
multiple interactions
|
ISO
|
sodium propionate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
|
CTD |
PMID:31621310 |
|
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125
|
|
G
|
Cyp1b1
|
cytochrome P450, family 1, subfamily b, polypeptide 1
|
multiple interactions
|
ISO
|
sodium propionate promotes the reaction [biochanin A results in increased expression of CYP1B1 mRNA]; sodium propionate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]
|
CTD |
PMID:31621310 |
|
NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:15,342,344...15,350,917
|
|
G
|
Hdac2
|
histone deacetylase 2
|
multiple interactions
|
ISO
|
sodium propionate inhibits the reaction [Ethanol results in increased expression of HDAC2 mRNA]; sodium propionate inhibits the reaction [Ethanol results in increased expression of HDAC2 protein]
|
CTD |
PMID:35639301 |
|
NCBI chr20:42,101,815...42,126,486
Ensembl chr20:40,548,250...40,571,609
|
|
G
|
Hdac6
|
histone deacetylase 6
|
multiple interactions
|
ISO
|
sodium propionate inhibits the reaction [Ethanol results in increased expression of HDAC6 mRNA]
|
CTD |
PMID:35639301 |
|
NCBI chr X:17,222,538...17,244,373
Ensembl chr X:14,551,044...14,572,441
|
|
G
|
Ifng
|
interferon gamma
|
multiple interactions
|
ISO
|
[Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in increased expression of IFNG mRNA]
|
CTD |
PMID:37269894 |
|
NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375
|
|
G
|
Ikbkb
|
inhibitor of nuclear factor kappa B kinase subunit beta
|
multiple interactions
|
ISO
|
[Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in increased expression of IKBKB mRNA]; [Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in increased expression of IKBKB protein]
|
CTD |
PMID:37269894 |
|
NCBI chr16:76,021,968...76,075,717
Ensembl chr16:69,319,554...69,373,250
|
|
G
|
Il6
|
interleukin 6
|
multiple interactions
|
ISO
|
[Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in increased expression of IL6 mRNA]
|
CTD |
PMID:37269894 |
|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178
|
|
G
|
Mt1
|
metallothionein 1
|
multiple interactions increases expression
|
EXP
|
[sodium propionate co-treated with Cadmium] results in increased expression of MT1A mRNA; [sodium propionate co-treated with Dexamethasone] results in increased expression of MT1A mRNA sodium propionate results in increased expression of MT1A mRNA
|
CTD |
PMID:1597404 |
|
NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049 Ensembl chr X:10,826,032...10,827,049
|
|
G
|
Myd88
|
MYD88, innate immune signal transduction adaptor
|
multiple interactions
|
ISO
|
[Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in increased expression of MYD88 mRNA]
|
CTD |
PMID:37269894 |
|
NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415
|
|
G
|
Nfkbia
|
NFKB inhibitor alpha
|
multiple interactions
|
ISO
|
[Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in decreased expression of NFKBIA protein]
|
CTD |
PMID:37269894 |
|
NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941
|
|
G
|
Nos2
|
nitric oxide synthase 2
|
multiple interactions
|
ISO
|
sodium propionate inhibits the reaction [Ethanol results in increased expression of NOS2 mRNA]
|
CTD |
PMID:35639301 |
|
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:63,815,308...63,851,210
|
|
G
|
Nox1
|
NADPH oxidase 1
|
multiple interactions
|
ISO
|
sodium propionate inhibits the reaction [Ethanol results in increased expression of NOX1 mRNA]; sodium propionate inhibits the reaction [TNF protein affects the acetylation of NOX1 promoter]
|
CTD |
PMID:35639301 |
|
NCBI chr X:101,572,338...101,625,571
Ensembl chr X:97,279,056...97,302,236
|
|
G
|
Ocln
|
occludin
|
multiple interactions
|
ISO
|
sodium propionate inhibits the reaction [Ethanol results in decreased expression of OCLN protein]
|
CTD |
PMID:35639301 |
|
NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:31,657,220...31,764,150
|
|
G
|
Rela
|
RELA proto-oncogene, NF-kB subunit
|
multiple interactions
|
ISO
|
[Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in increased expression of and results in increased phosphorylation of RELA protein]; [Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in increased expression of RELA mRNA]
|
CTD |
PMID:37269894 |
|
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484
|
|
G
|
Tgfb1
|
transforming growth factor, beta 1
|
multiple interactions
|
ISO
|
[Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in increased expression of TGFB1 mRNA]
|
CTD |
PMID:37269894 |
|
NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847
|
|
G
|
Tjp1
|
tight junction protein 1
|
multiple interactions
|
ISO
|
sodium propionate inhibits the reaction [Ethanol results in decreased expression of TJP1 protein]
|
CTD |
PMID:35639301 |
|
NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:118,849,838...119,094,432
|
|
G
|
Tlr2
|
toll-like receptor 2
|
multiple interactions
|
ISO
|
[Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in increased expression of TLR2 mRNA]; [Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in increased expression of TLR2 protein]
|
CTD |
PMID:37269894 |
|
NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630
|
|
G
|
Tlr4
|
toll-like receptor 4
|
multiple interactions
|
ISO
|
[Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in increased expression of TLR4 mRNA]; [Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in increased expression of TLR4 protein]
|
CTD |
PMID:37269894 |
|
NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628
|
|
G
|
Tnf
|
tumor necrosis factor
|
multiple interactions
|
ISO
|
[Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in increased expression of TNF mRNA]; sodium propionate inhibits the reaction [TNF protein affects the acetylation of NOX1 promoter]
|
CTD |
PMID:35639301 PMID:37269894 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
|
|
G
|
Ugt1a1
|
UDP glucuronosyltransferase family 1 member A1
|
multiple interactions
|
ISO
|
sodium propionate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of UGT1A1 mRNA]
|
CTD |
PMID:31621310 |
|
NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:88,713,184...88,808,465
|
|
|
G
|
Abcc1
|
ATP binding cassette subfamily C member 1
|
multiple interactions
|
ISO
|
[Lovastatin results in decreased activity of ABCC1 protein] which results in increased susceptibility to Antimony Sodium Gluconate
|
CTD |
PMID:18056276 |
|
NCBI chr10:1,022,041...1,162,431
Ensembl chr10:531,812...655,114
|
|
G
|
Bcl6
|
BCL6, transcription repressor
|
decreases expression
|
ISO
|
Antimony Sodium Gluconate results in decreased expression of BCL6 protein
|
CTD |
PMID:27546522 |
|
NCBI chr11:90,358,753...90,382,049
Ensembl chr11:76,854,090...76,877,389
|
|
G
|
Ccl2
|
C-C motif chemokine ligand 2
|
decreases expression
|
ISO
|
Antimony Sodium Gluconate results in decreased expression of CCL2 mRNA
|
CTD |
PMID:20102417 |
|
NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,005,424...67,007,226
|
|
G
|
Epo
|
erythropoietin
|
decreases expression
|
ISO
|
Antimony Sodium Gluconate results in decreased expression of EPO mRNA; Antimony Sodium Gluconate results in decreased expression of EPO protein
|
CTD |
PMID:9531339 |
|
NCBI chr12:24,841,285...24,844,725
Ensembl chr12:19,204,508...19,207,946
|
|
G
|
Icam1
|
intercellular adhesion molecule 1
|
affects response to substance
|
ISO
|
ICAM1 protein affects the susceptibility to Antimony Sodium Gluconate
|
CTD |
PMID:11035738 |
|
NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:19,553,645...19,565,438
|
|
G
|
Ifng
|
interferon gamma
|
decreases expression multiple interactions affects response to substance
|
ISO
|
Antimony Sodium Gluconate results in decreased expression of IFNG mRNA [IFNG protein co-treated with Antimony Sodium Gluconate] results in decreased expression of IL10 mRNA; [IFNG protein co-treated with Antimony Sodium Gluconate] results in decreased expression of IL4 mRNA; [IFNG protein co-treated with Antimony Sodium Gluconate] results in increased expression of IL12B mRNA; [IFNG protein co-treated with Antimony Sodium Gluconate] results in increased expression of NOS2 mRNA; IFNG protein affects the reaction [IL10RA protein affects the susceptibility to Antimony Sodium Gluconate] IFNG protein affects the susceptibility to Antimony Sodium Gluconate [Antimony Sodium Gluconate co-treated with Amphotericin B] results in increased expression of IFNG protein
|
CTD |
PMID:9234779 PMID:9498473 PMID:10603400 PMID:12870129 PMID:17911647 PMID:20102417 More...
|
|
NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375
|
|
G
|
Ifngr1
|
interferon gamma receptor 1
|
increases expression
|
ISO
|
Antimony Sodium Gluconate results in increased expression of IFNGR1 mRNA; Antimony Sodium Gluconate results in increased expression of IFNGR1 protein
|
CTD |
PMID:12803856 |
|
NCBI chr 1:16,152,811...16,171,439
Ensembl chr 1:14,333,187...14,351,785
|
|
G
|
Il10
|
interleukin 10
|
multiple interactions decreases expression affects response to substance
|
ISO
|
[Antimony Sodium Gluconate co-treated with Amphotericin B] results in decreased expression of IL10 protein Antimony Sodium Gluconate results in decreased expression of IL10 mRNA IL10 protein affects the susceptibility to Antimony Sodium Gluconate [IFNG protein co-treated with Antimony Sodium Gluconate] results in decreased expression of IL10 mRNA
|
CTD |
PMID:9234779 PMID:9498473 PMID:12379707 PMID:17911647 PMID:20102417 |
|
NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313
|
|
G
|
Il10ra
|
interleukin 10 receptor subunit alpha
|
multiple interactions affects response to substance
|
ISO
|
IFNG protein affects the reaction [IL10RA protein affects the susceptibility to Antimony Sodium Gluconate]
|
CTD |
PMID:12379707 PMID:12870129 |
|
NCBI chr 8:54,459,754...54,474,786
Ensembl chr 8:45,563,137...45,578,061
|
|
G
|
Il12b
|
interleukin 12B
|
multiple interactions
|
ISO
|
[IFNG protein co-treated with Antimony Sodium Gluconate] results in increased expression of IL12B mRNA
|
CTD |
PMID:9234779 |
|
NCBI chr10:29,390,300...29,405,194
Ensembl chr10:28,893,008...28,902,903
|
|
G
|
Il1b
|
interleukin 1 beta
|
decreases expression
|
ISO
|
Antimony Sodium Gluconate results in decreased expression of IL1B mRNA
|
CTD |
PMID:20102417 |
|
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415
|
|
G
|
Il4
|
interleukin 4
|
decreases expression multiple interactions affects response to substance
|
ISO
|
Antimony Sodium Gluconate results in decreased expression of IL4 mRNA [IFNG protein co-treated with Antimony Sodium Gluconate] results in decreased expression of IL4 mRNA IL4 protein affects the susceptibility to Antimony Sodium Gluconate
|
CTD |
PMID:7960131 PMID:9234779 PMID:11069076 PMID:20102417 |
|
NCBI chr10:38,272,003...38,277,549
Ensembl chr10:37,771,203...37,776,750
|
|
G
|
Itgam
|
integrin subunit alpha M
|
increases expression
|
ISO
|
Antimony Sodium Gluconate results in increased expression of ITGAM protein
|
CTD |
PMID:12399974 |
|
NCBI chr 1:192,089,496...192,139,947
Ensembl chr 1:182,659,000...182,709,503
|
|
G
|
Nos2
|
nitric oxide synthase 2
|
multiple interactions
|
ISO
|
[IFNG protein co-treated with Antimony Sodium Gluconate] results in increased expression of NOS2 mRNA
|
CTD |
PMID:9234779 |
|
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:63,815,308...63,851,210
|
|
G
|
Ptpn6
|
protein tyrosine phosphatase, non-receptor type 6
|
decreases activity
|
ISO
|
Antimony Sodium Gluconate results in decreased activity of PTPN6 protein
|
CTD |
PMID:12399974 |
|
NCBI chr 4:159,212,320...159,237,069
Ensembl chr 4:157,526,035...157,550,984
|
|
G
|
Tgfb1
|
transforming growth factor, beta 1
|
multiple interactions
|
ISO
|
[Antimony Sodium Gluconate co-treated with Amphotericin B] results in decreased expression of TGFB1 protein
|
CTD |
PMID:17911647 |
|
NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847
|
|
G
|
Tnf
|
tumor necrosis factor
|
decreases expression
|
ISO
|
Antimony Sodium Gluconate results in decreased expression of TNF mRNA
|
CTD |
PMID:20102417 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
|
|
G
|
Tnfrsf18
|
TNF receptor superfamily member 18
|
increases response to substance
|
ISO
|
TNFRSF18 protein results in increased susceptibility to Antimony Sodium Gluconate
|
CTD |
PMID:20139272 |
|
NCBI chr 5:166,618,461...166,622,353
Ensembl chr 5:166,618,969...166,622,353
|
|
G
|
Tnfrsf1a
|
TNF receptor superfamily member 1A
|
decreases expression
|
ISO
|
Antimony Sodium Gluconate results in decreased expression of TNFRSF1A protein
|
CTD |
PMID:7844400 |
|
NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:158,150,820...158,163,591
|
|
G
|
Tnfrsf1b
|
TNF receptor superfamily member 1B
|
decreases expression
|
ISO
|
Antimony Sodium Gluconate results in decreased expression of TNFRSF1B protein
|
CTD |
PMID:7844400 |
|
NCBI chr 5:162,356,250...162,387,411
Ensembl chr 5:157,070,642...157,104,206
|
|
|
G
|
Hdac8
|
histone deacetylase 8
|
decreases activity
|
EXP
|
Sodium valproate attenuates the reaction [deoxycorticosterone acetate increases activity of Hdac8 protein in the heart]
|
RGD |
PMID:23868068 |
RGD:9681716 |
NCBI chr X:67,385,288...67,593,014
Ensembl chr X:67,385,289...67,592,923
|
|
|
G
|
Abcb1a
|
ATP binding cassette subfamily B member 1A
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of ABCB1 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:25,158,362...25,442,709
|
|
G
|
Abcb4
|
ATP binding cassette subfamily B member 4
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of ABCB4 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 4:26,106,895...26,164,440
Ensembl chr 4:25,151,953...25,209,202
|
|
G
|
Abcc1
|
ATP binding cassette subfamily C member 1
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of ABCC1 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr10:1,022,041...1,162,431
Ensembl chr10:531,812...655,114
|
|
G
|
Abcc2
|
ATP binding cassette subfamily C member 2
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of ABCC2 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:242,664,657...242,723,238
|
|
G
|
Abcc3
|
ATP binding cassette subfamily C member 3
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of ABCC3 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,296,693...79,342,595
|
|
G
|
Abcc4
|
ATP binding cassette subfamily C member 4
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of ABCC4 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr15:101,948,387...102,182,912
Ensembl chr15:95,542,315...95,774,283
|
|
G
|
Abcg2
|
ATP binding cassette subfamily G member 2
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of ABCG2 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:87,745,319...87,802,409
|
|
G
|
Abcg5
|
ATP binding cassette subfamily G member 5
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of ABCG5 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 6:15,717,936...15,743,376
Ensembl chr 6:9,965,118...9,990,563
|
|
G
|
Abcg8
|
ATP binding cassette subfamily G member 8
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of ABCG8 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 6:15,698,448...15,717,730
Ensembl chr 6:9,945,629...9,964,912
|
|
G
|
Adgrg1
|
adhesion G protein-coupled receptor G1
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of ADGRG1 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr19:10,003,963...10,041,122
Ensembl chr19:10,003,975...10,041,108
|
|
G
|
Adh1c
|
alcohol dehydrogenase 1C (class I), gamma polypeptide
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of ADH1C mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
|
|
G
|
Adh4
|
alcohol dehydrogenase 4 (class II), pi polypeptide
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of ADH4 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 2:229,622,092...229,640,120
Ensembl chr 2:226,947,466...226,987,591
|
|
G
|
Adh6
|
alcohol dehydrogenase 6 (class V)
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of ADH6 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 2:229,576,612...229,608,359
Ensembl chr 2:226,903,250...226,934,534
|
|
G
|
Akr1d1
|
aldo-keto reductase family 1, member D1
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of AKR1D1 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372
|
|
G
|
Akr7a2
|
aldo-keto reductase family 7, member A2
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of AKR7A2 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909
|
|
G
|
Akr7a3
|
aldo-keto reductase family 7 member A3
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of AKR7A3 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
|
|
G
|
Alb
|
albumin
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of ALB mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,607,381...17,622,836
|
|
G
|
Ampd3
|
adenosine monophosphate deaminase 3
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of AMPD3 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 1:164,884,823...164,929,899
Ensembl chr 1:164,885,320...164,929,887
|
|
G
|
Apoa1
|
apolipoprotein A1
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of APOA1 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:46,527,144...46,529,035
|
|
G
|
Atp8b1
|
ATPase phospholipid transporting 8B1
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of ATP8B1 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr18:58,016,382...58,157,213
Ensembl chr18:58,018,268...58,157,396
|
|
G
|
Baat
|
bile acid CoA:amino acid N-acyltransferase
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of BAAT mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 5:68,647,166...68,656,137
Ensembl chr 5:63,850,705...63,860,685
|
|
G
|
Bach1
|
BTB domain and CNC homolog 1
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of BACH1 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447
|
|
G
|
Bcl2l1
|
Bcl2-like 1
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of BCL2L1 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:141,253,523...141,303,479 Ensembl chr 1:141,253,523...141,303,479
|
|
G
|
Casp9
|
caspase 9
|
multiple interactions
|
EXP
|
[Tartrazine co-treated with Erythrosine] affects the expression of CASP9 mRNA
|
CTD |
PMID:32981412 |
|
Ensembl chr 5:154,109,046...154,126,626
|
|
G
|
Cat
|
catalase
|
decreases activity multiple interactions
|
EXP ISO
|
Tartrazine results in decreased activity of CAT protein [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of CAT mRNA
|
CTD |
PMID:20678534 PMID:33819548 |
|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478
|
|
G
|
Chrna4
|
cholinergic receptor nicotinic alpha 4 subunit
|
multiple interactions
|
EXP
|
[ponceau 4R co-treated with Allura Red AC Dye co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt co-treated with Tartrazine co-treated with Amaranth Dye co-treated with brilliant blue co-treated with Indigo Carmine] results in decreased expression of CHRNA4 protein
|
CTD |
PMID:23429044 |
|
NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
|
|
G
|
Chrnb2
|
cholinergic receptor nicotinic beta 2 subunit
|
multiple interactions
|
EXP
|
[ponceau 4R co-treated with Allura Red AC Dye co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt co-treated with Tartrazine co-treated with Amaranth Dye co-treated with brilliant blue co-treated with Indigo Carmine] results in increased expression of CHRNB2 protein
|
CTD |
PMID:23429044 |
|
NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
|
|
G
|
Csf1
|
colony stimulating factor 1
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of CSF1 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 2:198,065,400...198,084,774
Ensembl chr 2:195,377,215...195,411,704
|
|
G
|
Cyp2b3
|
cytochrome P450, family 2, subfamily b, polypeptide 3
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of CYP2B6 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 1:90,780,468...90,859,852
Ensembl chr 1:81,652,787...81,732,143
|
|
G
|
Cyp2c11
|
cytochrome P450, subfamily 2, polypeptide 11
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of CYP2C18 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 1:246,175,216...246,211,445
Ensembl chr 1:236,762,842...236,799,066
|
|
G
|
Cyp3a2
|
cytochrome P450, family 3, subfamily a, polypeptide 2
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of CYP3A4 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr12:14,321,771...14,343,886
Ensembl chr12:9,015,383...9,285,008
|
|
G
|
Cyp3a9
|
cytochrome P450, family 3, subfamily a, polypeptide 9
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of CYP3A5 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr12:21,919,955...21,960,160
Ensembl chr12:16,806,207...16,846,422
|
|
G
|
Cyp7a1
|
cytochrome P450 family 7 subfamily A member 1
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of CYP7A1 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
|
|
G
|
Cyp7b1
|
cytochrome P450 family 7 subfamily B member 1
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of CYP7B1 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
|
|
G
|
Cyp8b1
|
cytochrome P450 family 8 subfamily B member 1
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of CYP8B1 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 8:130,455,622...130,457,592
Ensembl chr 8:121,557,062...121,580,166
|
|
G
|
Dnajb9
|
DnaJ heat shock protein family (Hsp40) member B9
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of DNAJB9 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 6:66,997,842...67,007,371
Ensembl chr 6:61,269,913...61,275,063
|
|
G
|
Dnajc10
|
DnaJ heat shock protein family (Hsp40) member C10
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of DNAJC10 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 3:65,232,031...65,272,732
Ensembl chr 3:65,232,697...65,272,719
|
|
G
|
Dnajc18
|
DnaJ heat shock protein family (Hsp40) member C18
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of DNAJC18 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr18:27,269,350...27,303,453
Ensembl chr18:27,269,355...27,298,344
|
|
G
|
Dnajc9
|
DnaJ heat shock protein family (Hsp40) member C9
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of DNAJC9 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr15:3,970,843...4,003,009
Ensembl chr15:3,923,268...3,928,118
|
|
G
|
Eif2ak3
|
eukaryotic translation initiation factor 2 alpha kinase 3
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of EIF2AK3 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:102,805,510...102,866,911
|
|
G
|
Esr1
|
estrogen receptor 1
|
increases activity multiple interactions
|
ISO
|
Tartrazine results in increased activity of ESR1 protein fulvestrant inhibits the reaction [Tartrazine results in increased activity of ESR1 protein]
|
CTD |
PMID:22562034 |
|
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002
|
|
G
|
Fmo1
|
flavin containing dimethylaniline monoxygenase 1
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of FMO1 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647
|
|
G
|
Fth1
|
ferritin heavy chain 1
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of FTH1 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 1:216,052,037...216,054,325
Ensembl chr 1:206,627,103...206,725,424
|
|
G
|
Gclm
|
glutamate cysteine ligase, modifier subunit
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of GCLM mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:210,347,482...210,367,535
|
|
G
|
Gjb2
|
gap junction protein, beta 2
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of GJB2 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr15:35,375,977...35,393,817
Ensembl chr15:31,260,357...31,278,177
|
|
G
|
Gprc5b
|
G protein-coupled receptor, class C, group 5, member B
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of GPRC5B mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 1:173,316,904...173,340,933
Ensembl chr 1:173,316,907...173,340,932
|
|
G
|
Grin2a
|
glutamate ionotropic receptor NMDA type subunit 2A
|
multiple interactions
|
EXP
|
[ponceau 4R co-treated with Allura Red AC Dye co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt co-treated with Tartrazine co-treated with Amaranth Dye co-treated with brilliant blue co-treated with Indigo Carmine] results in decreased expression of GRIN2A protein; [ponceau 4R co-treated with Allura Red AC Dye co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt co-treated with Tartrazine co-treated with Amaranth Dye co-treated with brilliant blue co-treated with Indigo Carmine] results in increased expression of GRIN2A protein
|
CTD |
PMID:23429044 |
|
NCBI chr10:6,136,458...6,560,003
Ensembl chr10:5,631,369...6,044,637
|
|
G
|
Gsta1
|
glutathione S-transferase alpha 1
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of GSTA1 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:23,703,477...23,720,121
|
|
G
|
Gsta4
|
glutathione S-transferase alpha 4
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of GSTA4 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 8:87,947,247...87,964,490
Ensembl chr 8:79,066,934...79,084,182
|
|
G
|
Gstt1
|
glutathione S-transferase theta 1
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of GSTT1 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
|
|
G
|
Havcr1
|
hepatitis A virus cellular receptor 1
|
multiple interactions
|
EXP
|
[Tartrazine co-treated with Erythrosine] affects the expression of HAVCR1 mRNA
|
CTD |
PMID:32981412 |
|
NCBI chr10:31,619,914...31,652,955
Ensembl chr10:31,119,088...31,151,698
|
|
G
|
Hpx
|
hemopexin
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of HPX mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328
|
|
G
|
Ifi27
|
interferon, alpha-inducible protein 27
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of IFI27 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 6:122,590,461...122,596,996
Ensembl chr 6:122,590,472...122,779,294
|
|
G
|
Il1r1
|
interleukin 1 receptor type 1
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of IL1R1 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 9:50,000,558...50,076,579
Ensembl chr 9:42,504,735...42,579,937
|
|
G
|
Jun
|
Jun proto-oncogene, AP-1 transcription factor subunit
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of JUN mRNA; [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of JUN mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656
|
|
G
|
Lipc
|
lipase C, hepatic type
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of LIPC mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
|
|
G
|
Ly96
|
lymphocyte antigen 96
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of LY96 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 5:2,582,233...2,612,357
Ensembl chr 5:2,582,254...2,612,386
|
|
G
|
Maf
|
MAF bZIP transcription factor
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of MAF mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr19:60,259,200...60,622,145
Ensembl chr19:43,360,342...43,712,365
|
|
G
|
Maff
|
MAF bZIP transcription factor F
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of MAFF mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 7:112,792,787...112,804,139
Ensembl chr 7:110,912,499...110,923,851
|
|
G
|
Map2k2
|
mitogen activated protein kinase kinase 2
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of MAP2K2 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 7:9,241,449...9,264,216
Ensembl chr 7:8,580,905...8,610,243
|
|
G
|
Map2k6
|
mitogen-activated protein kinase kinase 6
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of MAP2K6 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr10:95,872,747...95,987,747
Ensembl chr10:95,373,204...95,488,293
|
|
G
|
Map3k5
|
mitogen-activated protein kinase kinase kinase 5
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of MAP3K5 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 1:16,505,387...16,723,899
Ensembl chr 1:14,685,492...14,904,800
|
|
G
|
Mapkapk3
|
MAPK activated protein kinase 3
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of MAPKAPK3 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 8:116,808,429...116,842,228
Ensembl chr 8:107,929,762...107,963,568
|
|
G
|
Mgst1
|
microsomal glutathione S-transferase 1
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of MGST1 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892
|
|
G
|
Mlkl
|
mixed lineage kinase domain like pseudokinase
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of MLKL mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr19:39,277,526...39,304,555
Ensembl chr19:39,276,785...39,304,502
|
|
G
|
Mmut
|
methylmalonyl-CoA mutase
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of MMUT mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 9:19,928,720...19,956,985
Ensembl chr 9:19,928,727...19,957,046
|
|
G
|
Mttp
|
microsomal triglyceride transfer protein
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of MTTP mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
|
|
G
|
Nr0b2
|
nuclear receptor subfamily 0, group B, member 2
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of NR0B2 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609
|
|
G
|
Nr1h4
|
nuclear receptor subfamily 1, group H, member 4
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of NR1H4 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:23,846,122...23,942,047
|
|
G
|
Nr1i2
|
nuclear receptor subfamily 1, group I, member 2
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of NR1I2 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr11:75,965,717...76,006,733
Ensembl chr11:62,460,213...62,496,658
|
|
G
|
Nr1i3
|
nuclear receptor subfamily 1, group I, member 3
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of NR1I3 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr13:86,165,327...86,170,362
Ensembl chr13:83,632,899...83,637,906
|
|
G
|
Pah
|
phenylalanine hydroxylase
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of PAH mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:21,933,179...21,998,130
|
|
G
|
Pik3c2a
|
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of PIK3C2A mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 1:170,577,942...170,684,353
Ensembl chr 1:170,577,942...170,683,472
|
|
G
|
Pik3c2g
|
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of PIK3C2G mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 4:172,483,752...172,851,623
Ensembl chr 4:172,484,345...172,850,544
|
|
G
|
Pik3r3
|
phosphoinositide-3-kinase regulatory subunit 3
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of PIK3R3 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 5:134,936,790...135,009,303
Ensembl chr 5:129,701,229...129,772,583
|
|
G
|
Ppp1r3c
|
protein phosphatase 1, regulatory subunit 3C
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of PPP1R3C mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 1:243,873,524...243,878,527
Ensembl chr 1:234,460,652...234,465,961
|
|
G
|
Prkd3
|
protein kinase D3
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of PRKD3 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 6:16,032,507...16,108,444
Ensembl chr 6:16,032,585...16,108,443
|
|
G
|
Rara
|
retinoic acid receptor, alpha
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of RARA mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr10:84,379,780...84,424,371
Ensembl chr10:83,893,384...83,928,142
|
|
G
|
Rasd1
|
ras related dexamethasone induced 1
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of RASD1 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr10:44,766,451...44,775,773
Ensembl chr10:44,766,455...44,768,186
|
|
G
|
Rdh16
|
retinol dehydrogenase 16
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of RDH16 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 7:63,616,711...63,625,053
Ensembl chr 7:63,597,536...63,624,124
|
|
G
|
Serpine1
|
serpin family E member 1
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of SERPINE1 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr12:25,237,977...25,248,356
Ensembl chr12:19,601,272...19,611,657
|
|
G
|
Slc10a1
|
solute carrier family 10 member 1
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of SLC10A1 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670
|
|
G
|
Slc22a1
|
solute carrier family 22 member 1
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of SLC22A1 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
|
|
G
|
Sod2
|
superoxide dismutase 2
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of SOD2 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189
|
|
G
|
Sorl1
|
sortilin related receptor 1
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of SORL1 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 8:51,238,713...51,401,458
Ensembl chr 8:42,341,704...42,504,513
|
|
G
|
Srebf1
|
sterol regulatory element binding transcription factor 1
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of SREBF1 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,007,637...45,029,650
|
|
G
|
Sult2a1
|
sulfotransferase family 2A member 1
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of SULT2A1 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 1:84,582,011...84,639,001
Ensembl chr 1:74,911,100...75,508,134
|
|
G
|
Tff1
|
trefoil factor 1
|
multiple interactions increases expression
|
ISO
|
fulvestrant inhibits the reaction [Tartrazine results in increased expression of TFF1 mRNA]
|
CTD |
PMID:22562034 |
|
NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
|
|
G
|
Tlr3
|
toll-like receptor 3
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of TLR3 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545
|
|
G
|
Tlr4
|
toll-like receptor 4
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of TLR4 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628
|
|
G
|
Tnf
|
tumor necrosis factor
|
multiple interactions
|
EXP
|
[Tartrazine co-treated with Erythrosine] results in increased expression of TNF mRNA
|
CTD |
PMID:32981412 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
|
|
G
|
Tnfrsf9
|
TNF receptor superfamily member 9
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of TNFRSF9 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 5:166,664,494...166,690,834
Ensembl chr 5:161,381,662...161,408,000
|
|
G
|
Tnfsf10
|
TNF superfamily member 10
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of TNFSF10 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
|
|
G
|
Tnfsf11
|
TNF superfamily member 11
|
multiple interactions
|
ISO
|
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of TNFSF11 mRNA
|
CTD |
PMID:33819548 |
|
NCBI chr15:60,083,008...60,114,479
Ensembl chr15:53,673,877...53,705,445
|
|
|
G
|
Abhd17b
|
abhydrolase domain containing 17B, depalmitoylase
|
increases expression
|
ISO
|
Thimerosal results in increased expression of ABHD17B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:219,198,294...219,232,733
Ensembl chr 1:219,198,471...219,231,933
|
|
G
|
Abtb3
|
ankyrin repeat and BTB domain containing 3
|
multiple interactions
|
ISO
|
[NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABTB3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:18,035,151...18,310,718
Ensembl chr 7:18,036,083...18,310,834
|
|
G
|
Acacb
|
acetyl-CoA carboxylase beta
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ACACB mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr12:48,026,394...48,138,214
Ensembl chr12:42,366,548...42,457,655
|
|
G
|
Acsl4
|
acyl-CoA synthetase long-chain family member 4
|
increases expression
|
ISO
|
Thimerosal results in increased expression of ACSL4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr X:110,739,633...110,803,416
Ensembl chr X:105,942,799...106,006,427
|
|
G
|
Actmap
|
actin maturation protease
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ACTMAP mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:82,490,313...82,499,841
Ensembl chr 1:82,490,363...82,499,841
|
|
G
|
Actr2
|
actin related protein 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ACTR2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr14:94,296,443...94,333,735
Ensembl chr14:94,296,443...94,340,524
|
|
G
|
Adcy7
|
adenylate cyclase 7
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ADCY7 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr19:18,740,875...18,798,924
Ensembl chr19:18,740,875...18,776,311
|
|
G
|
Adgrb2
|
adhesion G protein-coupled receptor B2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ADGRB2 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 5:142,299,190...142,362,540
Ensembl chr 5:142,331,329...142,362,540
|
|
G
|
Adgrl3
|
adhesion G protein-coupled receptor L3
|
increases expression
|
ISO
|
Thimerosal results in increased expression of ADGRL3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr14:26,336,320...27,104,060
Ensembl chr14:26,368,277...27,105,860
|
|
G
|
Adgrv1
|
adhesion G protein-coupled receptor V1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of ADGRV1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:11,331,434...11,911,713
Ensembl chr 2:11,331,442...11,911,688
|
|
G
|
Adm
|
adrenomedullin
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ADM mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:174,164,178...174,182,372
Ensembl chr 1:164,745,466...164,747,654
|
|
G
|
Adss1
|
adenylosuccinate synthase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ADSS1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:131,679,795...131,702,012
Ensembl chr 6:131,679,701...131,701,998
|
|
G
|
Afap1l1
|
actin filament associated protein 1-like 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of AFAP1L1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr18:55,183,786...55,244,174
Ensembl chr18:55,183,786...55,244,146
|
|
G
|
Aff4
|
ALF transcription elongation factor 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of AFF4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:37,498,825...37,579,751
Ensembl chr10:37,498,825...37,579,751
|
|
G
|
Agbl5
|
AGBL carboxypeptidase 5
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of AGBL5 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:25,472,333...25,492,173
Ensembl chr 6:25,472,333...25,490,738
|
|
G
|
Agfg1
|
ArfGAP with FG repeats 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of AGFG1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:84,124,845...84,182,615
Ensembl chr 9:84,125,120...84,178,128
|
|
G
|
Ago1
|
argonaute RISC component 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of AGO1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:138,722,111...138,757,118
Ensembl chr 5:138,722,111...138,773,546
|
|
G
|
Agpat1
|
1-acylglycerol-3-phosphate O-acyltransferase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of AGPAT1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr20:4,135,955...4,144,880
Ensembl chr20:4,135,957...4,145,278
|
|
G
|
Ahcy
|
adenosylhomocysteinase
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of AHCY mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:143,569,134...143,584,359
Ensembl chr 3:143,569,094...143,584,393
|
|
G
|
Ahnak2
|
AHNAK nucleoprotein 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of AHNAK2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:131,830,668...131,876,311
Ensembl chr 6:131,831,454...131,854,463
|
|
G
|
Aifm1
|
apoptosis inducing factor, mitochondria associated 1
|
increases secretion
|
ISO
|
Thimerosal results in increased secretion of AIFM1 protein
|
CTD |
PMID:12140745 |
|
NCBI chr X:132,528,107...132,567,237
Ensembl chr X:127,650,226...127,689,256
|
|
G
|
Ak4
|
adenylate kinase 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of AK4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618
|
|
G
|
Akap11
|
A-kinase anchoring protein 11
|
increases expression
|
ISO
|
Thimerosal results in increased expression of AKAP11 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr15:53,911,635...53,956,138
Ensembl chr15:53,911,657...53,941,605
|
|
G
|
Akap8l
|
A-kinase anchoring protein 8 like
|
increases expression
|
ISO
|
Thimerosal results in increased expression of AKAP8L mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:11,332,671...11,362,287
Ensembl chr 7:11,332,672...11,362,275
|
|
G
|
Akap9
|
A-kinase anchoring protein 9
|
increases expression
|
ISO
|
Thimerosal results in increased expression of AKAP9 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:30,056,738...30,192,716
Ensembl chr 4:30,056,738...30,192,606
|
|
G
|
Akt1
|
AKT serine/threonine kinase 1
|
multiple interactions decreases phosphorylation
|
ISO
|
Thimerosal promotes the reaction [wortmannin results in decreased phosphorylation of AKT1 protein]; wortmannin promotes the reaction [Thimerosal results in decreased phosphorylation of AKT1 protein]
|
CTD |
PMID:23145070 |
|
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921
|
|
G
|
Akt3
|
AKT serine/threonine kinase 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of AKT3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr13:91,475,839...91,758,060
Ensembl chr13:88,946,091...89,225,708
|
|
G
|
Alas1
|
5'-aminolevulinate synthase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ALAS1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917
|
|
G
|
Alb
|
albumin
|
affects binding
|
ISO
|
Thimerosal binds to ALB protein
|
CTD |
PMID:18197631 |
|
NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,607,381...17,622,836
|
|
G
|
Aldh3a2
|
aldehyde dehydrogenase 3 family, member A2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ALDH3A2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:46,427,789...46,448,449
Ensembl chr10:45,908,524...45,949,281
|
|
G
|
Aldh5a1
|
aldehyde dehydrogenase 5 family, member A1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ALDH5A1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr17:40,132,339...40,158,677
Ensembl chr17:40,130,883...40,158,677
|
|
G
|
Aldh6a1
|
aldehyde dehydrogenase 6 family, member A1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ALDH6A1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:109,809,092...109,829,725
Ensembl chr 6:104,077,979...104,098,656
|
|
G
|
Aldoa
|
aldolase, fructose-bisphosphate A
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ALDOA mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:190,832,820...190,838,021
Ensembl chr 1:181,402,275...181,406,182
|
|
G
|
Aldoc
|
aldolase, fructose-bisphosphate C
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ALDOC mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:63,715,544...63,719,133
Ensembl chr10:63,217,451...63,221,066
|
|
G
|
Alg13
|
ALG13, UDP-N-acetylglucosaminyltransferase subunit
|
increases expression
|
ISO
|
Thimerosal results in increased expression of ALG13 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr X:107,906,320...107,968,232
Ensembl chr X:107,885,093...107,942,695
|
|
G
|
Alox5
|
arachidonate 5-lipoxygenase
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ALOX5 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:151,203,948...151,251,126
Ensembl chr 4:149,531,515...149,578,743
|
|
G
|
Angpt1
|
angiopoietin 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ANGPT1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:75,415,959...75,668,696
Ensembl chr 7:73,531,486...73,784,067
|
|
G
|
Ank2
|
ankyrin 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of ANK2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:218,052,555...218,628,414
Ensembl chr 2:215,379,680...215,862,923
|
|
G
|
Ankdd1a
|
ankyrin repeat and death domain containing 1A
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ANKDD1A mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:66,017,571...66,043,738
Ensembl chr 8:66,017,773...66,042,651
|
|
G
|
Ankef1
|
ankyrin repeat and EF-hand domain containing 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ANKEF1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:123,847,832...123,883,060
Ensembl chr 3:123,847,817...123,883,059
|
|
G
|
Ankrd10
|
ankyrin repeat domain 10
|
increases expression
|
ISO
|
Thimerosal results in increased expression of ANKRD10 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr16:77,866,489...77,889,745
Ensembl chr16:77,864,261...77,889,745
|
|
G
|
Ankrd35
|
ankyrin repeat domain 35
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ANKRD35 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:184,207,076...184,227,063
Ensembl chr 2:184,207,071...184,227,063
|
|
G
|
Ankrd37
|
ankyrin repeat domain 37
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ANKRD37 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr16:46,268,933...46,271,971
Ensembl chr16:46,268,443...46,271,963
|
|
G
|
Ankrd44
|
ankyrin repeat domain 44
|
increases expression
|
ISO
|
Thimerosal results in increased expression of ANKRD44 mRNA
|
CTD |
PMID:24675092 PMID:27188386 |
|
NCBI chr 9:56,126,746...56,427,661
Ensembl chr 9:56,126,747...56,427,508
|
|
G
|
Ankrd9
|
ankyrin repeat domain 9
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ANKRD9 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:130,001,914...130,008,792
Ensembl chr 6:129,998,486...130,008,923
|
|
G
|
Ano4
|
anoctamin 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ANO4 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 7:23,329,015...23,738,423
Ensembl chr 7:23,329,070...23,738,434
|
|
G
|
Anp32b
|
acidic nuclear phosphoprotein 32 family member B
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ANP32B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:65,538,872...65,561,305
Ensembl chr 5:60,743,443...60,765,717
|
|
G
|
Anpep
|
alanyl aminopeptidase, membrane
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ANPEP mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789
|
|
G
|
Apc
|
APC regulator of WNT signaling pathway
|
increases expression
|
ISO
|
Thimerosal results in increased expression of APC mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr18:26,138,382...26,196,021
Ensembl chr18:25,864,222...25,922,696
|
|
G
|
Apoh
|
apolipoprotein H
|
multiple interactions
|
ISO
|
[NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of APOH mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329
|
|
G
|
Appl2
|
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of APPL2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:22,019,480...22,072,386
Ensembl chr 7:20,135,375...20,184,754
|
|
G
|
Arap3
|
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ARAP3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr18:29,806,214...29,834,217
Ensembl chr18:29,807,536...29,833,555
|
|
G
|
Arb2a
|
ARB2 cotranscriptional regulator A
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ARB2A mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:7,553,873...8,018,183
Ensembl chr 2:7,553,891...8,018,162
|
|
G
|
Arc
|
activity-regulated cytoskeleton-associated protein
|
increases expression
|
ISO
|
Thimerosal results in increased expression of ARC mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378
|
|
G
|
Arfgef3
|
ARFGEF family member 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ARFGEF3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:13,245,578...13,404,319
Ensembl chr 1:13,244,830...13,404,084
|
|
G
|
Arglu1
|
arginine and glutamate rich 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ARGLU1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr16:80,753,300...80,777,350
Ensembl chr16:80,753,315...80,777,349
|
|
G
|
Arhgap18
|
Rho GTPase activating protein 18
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ARHGAP18 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:18,403,531...18,637,306
Ensembl chr 1:18,403,537...18,637,256
|
|
G
|
Arhgap5
|
Rho GTPase activating protein 5
|
increases expression
|
ISO
|
Thimerosal results in increased expression of ARHGAP5 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:69,975,904...70,039,299
Ensembl chr 6:69,976,214...70,037,660
|
|
G
|
Arhgef10
|
Rho guanine nucleotide exchange factor 10
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ARHGEF10 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr16:74,647,147...74,738,784
Ensembl chr16:74,647,153...74,738,173
|
|
G
|
Arhgef12
|
Rho guanine nucleotide exchange factor 12
|
increases expression
|
ISO
|
Thimerosal results in increased expression of ARHGEF12 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:43,350,070...43,475,404
Ensembl chr 8:43,353,799...43,476,366
|
|
G
|
Arhgef4
|
Rho guanine nucleotide exchange factor 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ARHGEF4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:36,861,800...37,005,079
Ensembl chr 9:36,861,835...37,005,075
|
|
G
|
Armc7
|
armadillo repeat containing 7
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ARMC7 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:100,723,080...100,739,636
Ensembl chr10:100,723,105...100,739,636
|
|
G
|
Armcx5
|
armadillo repeat containing, X-linked 5
|
increases expression
|
ISO
|
Thimerosal results in increased expression of ARMCX5 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr X:98,709,921...98,714,347
Ensembl chr X:98,709,841...98,714,674
|
|
G
|
Arnt
|
aryl hydrocarbon receptor nuclear translocator
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ARNT mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
|
|
G
|
Arpc1b
|
actin related protein 2/3 complex, subunit 1B
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ARPC1B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr12:14,595,939...14,609,501
Ensembl chr12:9,480,831...9,495,747
|
|
G
|
Arrdc3
|
arrestin domain containing 3
|
increases expression
|
ISO
|
Thimerosal results in increased expression of ARRDC3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:11,137,464...11,149,978
Ensembl chr 2:11,137,460...11,149,978
|
|
G
|
Arsk
|
arylsulfatase family, member K
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ARSK mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:5,574,319...5,631,451
Ensembl chr 2:5,574,322...5,631,467
|
|
G
|
Asf1a
|
anti-silencing function 1A histone chaperone
|
increases expression
|
ISO
|
Thimerosal results in increased expression of ASF1A mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr20:32,893,962...32,908,808
Ensembl chr20:32,893,573...32,908,808
|
|
G
|
Asmtl
|
acetylserotonin O-methyltransferase-like
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ASMTL mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr12:16,315,335...16,318,083
Ensembl chr12:16,315,414...16,318,080
|
|
G
|
Aspm
|
assembly factor for spindle microtubules
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ASPM mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr13:51,074,849...51,123,755
Ensembl chr13:51,074,849...51,123,755
|
|
G
|
Atad2b
|
ATPase family, AAA domain containing 2B
|
increases expression
|
ISO
|
Thimerosal results in increased expression of ATAD2B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:27,914,546...28,070,103
Ensembl chr 6:27,912,862...28,067,047
|
|
G
|
Atf3
|
activating transcription factor 3
|
increases expression
|
ISO
|
Thimerosal results in increased expression of ATF3 mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr13:105,274,103...105,331,653
Ensembl chr13:102,751,321...102,764,631
|
|
G
|
Atf7ip
|
activating transcription factor 7 interacting protein
|
increases expression
|
ISO
|
Thimerosal results in increased expression of ATF7IP mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:169,385,872...169,471,652
Ensembl chr 4:169,385,872...169,471,650
|
|
G
|
Atg10
|
autophagy related 10
|
increases expression
|
ISO
|
Thimerosal results in increased expression of ATG10 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:22,109,304...22,398,313
Ensembl chr 2:22,108,426...22,398,233
|
|
G
|
Atg13
|
autophagy related 13
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ATG13 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:77,647,069...77,681,028
Ensembl chr 3:77,645,790...77,681,043
|
|
G
|
Atg2b
|
autophagy related 2B
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ATG2B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:124,522,283...124,592,412
Ensembl chr 6:124,525,523...124,592,015
|
|
G
|
Atm
|
ATM serine/threonine kinase
|
increases expression
|
ISO
|
Thimerosal results in increased expression of ATM mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:53,831,093...53,932,437
|
|
G
|
Atp11b
|
ATPase phospholipid transporting 11B (putative)
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ATP11B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:118,585,348...118,691,076
Ensembl chr 2:118,585,342...118,690,232
|
|
G
|
Atp13a3
|
ATPase 13A3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ATP13A3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr11:83,860,725...83,946,899
Ensembl chr11:70,365,322...70,441,235
|
|
G
|
Atp1b2
|
ATPase Na+/K+ transporting subunit beta 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ATP1B2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:54,817,473...54,823,708
Ensembl chr10:54,318,701...54,324,933
|
|
G
|
Atp5f1d
|
ATP synthase F1 subunit delta
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ATP5F1D mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:10,211,260...10,218,989
Ensembl chr 7:9,560,608...9,565,929
|
|
G
|
Atp5f1e
|
ATP synthase F1 subunit epsilon
|
increases expression
|
ISO
|
Thimerosal results in increased expression of ATP5F1E mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:183,677,270...183,680,172
Ensembl chr 3:163,260,476...163,261,450
|
|
G
|
Atp5if1
|
ATP synthase inhibitory factor subunit 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ATP5IF1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:144,738,950...144,742,668
Ensembl chr 5:144,738,950...144,742,668
|
|
G
|
Atp6v1d
|
ATPase H+ transporting V1 subunit D
|
increases expression
|
ISO
|
Thimerosal results in increased expression of ATP6V1D mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:103,389,778...103,405,346
Ensembl chr 6:97,656,576...97,672,303
|
|
G
|
Atp8b3
|
ATPase phospholipid transporting 8B3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ATP8B3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:9,175,544...9,195,449
Ensembl chr 7:9,175,391...9,195,442
|
|
G
|
Atrx
|
ATRX, chromatin remodeler
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ATRX mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr X:74,916,548...75,062,880
Ensembl chr X:70,850,981...70,997,330
|
|
G
|
Atxn1
|
ataxin 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ATXN1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr17:18,737,491...19,142,360
Ensembl chr17:18,737,533...19,142,360
|
|
G
|
Atxn7l3b
|
ataxin 7-like 3B
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ATXN7L3B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:48,322,451...48,325,975
Ensembl chr 7:48,321,755...48,328,878
|
|
G
|
Azi2
|
5-azacytidine induced 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of AZI2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:126,651,268...126,674,795
Ensembl chr 8:117,773,279...117,797,847
|
|
G
|
B3galnt2
|
beta-1,3-N-acetylgalactosaminyltransferase 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of B3GALNT2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr17:56,030,409...56,072,952
Ensembl chr17:51,334,921...51,377,469
|
|
G
|
Bace1
|
beta-secretase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of BACE1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876
|
|
G
|
Bace2
|
beta-secretase 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of BACE2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr11:36,707,447...36,789,550
Ensembl chr11:36,707,458...36,789,546
|
|
G
|
Bag3
|
BAG cochaperone 3
|
increases expression
|
ISO
|
Thimerosal results in increased expression of BAG3 mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858
|
|
G
|
Bag4
|
BAG cochaperone 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of BAG4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr16:66,288,678...66,305,893
Ensembl chr16:66,288,678...66,308,663
|
|
G
|
Bax
|
BCL2 associated X, apoptosis regulator
|
increases expression
|
ISO
|
Thimerosal results in increased expression of BAX
|
CTD |
PMID:24942245 |
|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368
|
|
G
|
Bbip1
|
BBSome interacting protein 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of BBIP1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:252,943,589...252,959,512
Ensembl chr 1:252,945,557...252,959,352
|
|
G
|
Bbln
|
bublin coiled coil protein
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of BBLN mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:15,674,577...15,677,322
Ensembl chr 3:15,674,580...15,677,374
|
|
G
|
Bcas3
|
BCAS3, microtubule associated cell migration factor
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of BCAS3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:70,213,710...70,673,080
Ensembl chr10:70,214,098...70,673,080
|
|
G
|
Bcat2
|
branched chain amino acid transaminase 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of BCAT2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007
|
|
G
|
Bcl6b
|
BCL6B, transcription repressor
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of BCL6B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:55,439,566...55,444,631
Ensembl chr10:54,940,909...54,945,974
|
|
G
|
Bclaf1
|
BCL2-associated transcription factor 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of BCLAF1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:15,088,436...15,117,666
Ensembl chr 1:15,070,894...15,148,832
|
|
G
|
Bcor
|
BCL6 co-repressor
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of BCOR mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr X:10,609,756...10,729,613
Ensembl chr X:10,687,732...10,729,613
|
|
G
|
Bdp1
|
BDP1 general transcription factor IIIB subunit
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of BDP1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:31,378,407...31,470,140
Ensembl chr 2:31,378,924...31,470,119
|
|
G
|
Bhlhe40
|
basic helix-loop-helix family, member e40
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of BHLHE40 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:143,174,450...143,180,150
Ensembl chr 4:141,618,476...141,624,774
|
|
G
|
Birc3
|
baculoviral IAP repeat-containing 3
|
multiple interactions decreases expression
|
ISO
|
Glutathione inhibits the reaction [Thimerosal results in decreased expression of BIRC3 protein]
|
CTD |
PMID:12140745 |
|
NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
|
|
G
|
Birc5
|
baculoviral IAP repeat-containing 5
|
multiple interactions decreases expression
|
ISO
|
BIRC5 mutant form promotes the reaction [Thimerosal results in increased cleavage of CASP3 protein]; BIRC5 mutant form promotes the reaction [Thimerosal results in increased cleavage of CASP9 protein]; BIRC5 protein inhibits the reaction [Thimerosal results in increased cleavage of CASP3 protein]; BIRC5 protein inhibits the reaction [Thimerosal results in increased cleavage of CASP9 protein]; IGF1 protein inhibits the reaction [Thimerosal results in decreased expression of BIRC5 protein]; Thimerosal promotes the reaction [BIRC5 mutant form results in increased cleavage of CASP3 protein]; Thimerosal promotes the reaction [BIRC5 mutant form results in increased cleavage of CASP9 protein]
|
CTD |
PMID:23145070 |
|
NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,073,408...103,081,380
|
|
G
|
Bloc1s3
|
biogenesis of lysosomal organelles complex-1, subunit 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of BLOC1S3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:79,155,873...79,158,247
Ensembl chr 1:79,155,693...79,158,505
|
|
G
|
Bltp3a
|
bridge-like lipid transfer protein family member 3A
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of BLTP3A mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr20:5,910,261...5,954,641
Ensembl chr20:5,910,260...5,952,404
|
|
G
|
Bmp2k
|
BMP-2 inducible kinase
|
increases expression
|
ISO
|
Thimerosal results in increased expression of BMP2K mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr14:12,785,169...12,882,676
Ensembl chr14:12,484,729...12,579,134
|
|
G
|
Bnip3
|
BCL2 interacting protein 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of BNIP3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:193,708,167...193,725,359
|
|
G
|
Bod1l1
|
biorientation of chromosomes in cell division 1-like 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of BOD1L1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr14:69,108,483...69,163,255
Ensembl chr14:69,108,491...69,162,490
|
|
G
|
Bok
|
BCL2 family apoptosis regulator BOK
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of BOK mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:101,670,729...101,681,834
Ensembl chr 9:94,223,389...94,234,476
|
|
G
|
Bola2
|
bolA family member 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of BOLA2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:181,291,967...181,292,833
Ensembl chr 1:181,291,398...181,292,676
|
|
G
|
Brca2
|
BRCA2, DNA repair associated
|
increases expression
|
ISO
|
Thimerosal results in increased expression of BRCA2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr12:4,895,092...4,939,340
Ensembl chr12:59,819...100,567
|
|
G
|
Brwd1
|
bromodomain and WD repeat domain containing 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of BRWD1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr11:35,286,364...35,378,768
Ensembl chr11:35,288,313...35,378,768
|
|
G
|
Brwd3
|
bromodomain and WD repeat domain containing 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of BRWD3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr X:73,768,343...73,861,643
Ensembl chr X:73,774,340...73,861,622
|
|
G
|
Btg3
|
BTG anti-proliferation factor 3
|
increases expression
|
ISO
|
Thimerosal results in increased expression of BTG3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr11:17,030,156...17,046,069
Ensembl chr11:17,030,160...17,046,170
|
|
G
|
C11h3orf38
|
similar to human chromosome 3 open reading frame 38
|
increases expression
|
ISO
|
Thimerosal results in increased expression of C3ORF38 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr11:2,483,983...2,488,631
Ensembl chr11:2,481,189...2,488,660
|
|
G
|
C13h1orf115
|
similar to human chromosome 1 open reading frame 115
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of C1ORF115 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr13:96,422,308...96,432,044
Ensembl chr13:96,422,302...96,432,068
|
|
G
|
C13h1orf53
|
similar to human chromosome 1 open reading frame 53
|
increases expression
|
ISO
|
Thimerosal results in increased expression of C1ORF53 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr13:50,413,785...50,418,974
Ensembl chr13:50,413,785...50,419,120
|
|
G
|
C13h2orf76
|
similar to chromosome 2 open reading frame 76
|
increases expression
|
ISO
|
Thimerosal results in increased expression of C2ORF76 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr13:31,249,733...31,335,367
Ensembl chr13:31,249,959...31,314,943
|
|
G
|
C15h8orf58
|
similar to human chromosome 8 open reading frame 58
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of C8ORF58 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr15:45,228,615...45,235,274
Ensembl chr15:45,228,615...45,233,254
|
|
G
|
C16h8orf48
|
similar to human chromosome 8 open reading frame 48
|
increases expression
|
ISO
|
Thimerosal results in increased expression of C8ORF48 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr16:61,948,170...61,950,066
Ensembl chr16:55,236,322...55,246,650
|
|
G
|
C17h5orf24
|
similar to human chromosome 5 open reading frame 24
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of C5ORF24 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr17:8,923,041...8,932,958
Ensembl chr17:8,922,675...8,933,356
|
|
G
|
C1qtnf3
|
C1q and TNF related 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of C1QTNF3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:59,917,099...59,939,519
Ensembl chr 2:59,917,188...59,939,433
|
|
G
|
C1qtnf4
|
C1q and TNF related 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of C1QTNF4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:76,854,368...76,872,991
Ensembl chr 3:76,857,735...76,874,139
|
|
G
|
C1rl
|
complement C1r subcomponent like
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of C1RL mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:157,394,183...157,410,771
Ensembl chr 4:157,394,200...157,410,134
|
|
G
|
C20h6orf136
|
similar to human chromosome 6 open reading frame 136
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of C6ORF136 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr20:2,857,840...2,861,952
|
|
G
|
C2cd2
|
C2 calcium-dependent domain containing 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of C2CD2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr11:37,225,321...37,289,741
Ensembl chr11:37,227,415...37,289,739
|
|
G
|
C5h1orf174
|
similar to human chromosome 1 open reading frame 174
|
increases expression
|
ISO
|
Thimerosal results in increased expression of C1ORF174 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:164,515,578...164,520,022
Ensembl chr 5:164,515,559...164,520,021
|
|
G
|
C7h8orf82
|
similar to human chromosome 8 open reading frame 82
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of C8ORF82 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:108,443,772...108,446,116
Ensembl chr 7:108,443,782...108,446,121
|
|
G
|
Cadm2
|
cell adhesion molecule 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CADM2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr11:4,548,367...5,525,420
Ensembl chr11:4,555,159...5,525,400
|
|
G
|
Cadm3
|
cell adhesion molecule 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CADM3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr13:85,784,785...85,817,412
Ensembl chr13:85,786,483...85,817,749
|
|
G
|
Calm3
|
calmodulin 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CALM3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:86,718,761...86,725,869
Ensembl chr 1:77,589,230...77,592,207
|
|
G
|
Calml4
|
calmodulin-like 4
|
multiple interactions
|
ISO
|
[NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CALML4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:63,323,426...63,335,234
Ensembl chr 8:63,323,351...63,335,234
|
|
G
|
Capn5
|
calpain 5
|
multiple interactions
|
ISO
|
[NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CAPN5 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:152,416,252...152,472,923
Ensembl chr 1:152,416,252...152,472,923
|
|
G
|
Capn9
|
calpain 9
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CAPN9 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr19:52,549,448...52,586,413
Ensembl chr19:52,549,448...52,586,413
|
|
G
|
Car10
|
carbonic anhydrase 10
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CA10 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:78,551,067...79,053,421
Ensembl chr10:78,054,114...78,555,834
|
|
G
|
Car14
|
carbonic anhydrase 14
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CA14 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:186,131,196...186,138,164
Ensembl chr 2:183,441,667...183,449,693
|
|
G
|
Card10
|
caspase recruitment domain family, member 10
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CARD10 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:112,210,944...112,252,044
Ensembl chr 7:110,330,408...110,359,224
|
|
G
|
Carm1
|
coactivator-associated arginine methyltransferase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CARM1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:20,097,262...20,141,950
Ensembl chr 8:20,097,254...20,147,689
|
|
G
|
Casp3
|
caspase 3
|
increases cleavage multiple interactions increases activity
|
ISO EXP
|
Thimerosal results in increased cleavage of CASP3 protein [[Thimerosal results in increased abundance of Reactive Oxygen Species] which results in increased activity of CASP3 protein] which results in increased cleavage of PTK2 protein; [SOD1 protein results in increased susceptibility to Thimerosal] which results in increased cleavage of CASP3 protein; [Thimerosal results in increased abundance of Reactive Oxygen Species] which results in increased activity of CASP3 protein; Acetylcysteine inhibits the reaction [[[Thimerosal results in increased abundance of Reactive Oxygen Species] which results in increased activity of CASP3 protein] which results in increased cleavage of PTK2 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[[Thimerosal results in increased abundance of Reactive Oxygen Species] which results in increased activity of CASP3 protein] which results in increased cleavage of PTK2 protein]; Glutathione inhibits the reaction [Thimerosal results in increased activity of CASP3 protein]; Resveratrol inhibits the reaction [[SOD1 protein results in increased susceptibility to Thimerosal] which results in increased cleavage of CASP3 protein]; SB 203580 inhibits the reaction [Thimerosal results in increased activity of CASP3 protein] benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Thimerosal results in increased cleavage of CASP3 protein]; benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [Thimerosal results in increased cleavage of CASP3 protein]; BIRC5 mutant form promotes the reaction [Thimerosal results in increased cleavage of CASP3 protein]; BIRC5 protein inhibits the reaction [Thimerosal results in increased cleavage of CASP3 protein]; IGF1 protein inhibits the reaction [Thimerosal results in increased cleavage of CASP3 protein]; Thimerosal promotes the reaction [BIRC5 mutant form results in increased cleavage of CASP3 protein]; Thimerosal promotes the reaction [Wortmannin results in increased cleavage of CASP3 protein]; Wortmannin promotes the reaction [Thimerosal results in increased cleavage of CASP3 protein] MC1568 inhibits the reaction [Thimerosal results in increased cleavage of and results in increased activity of CASP3 protein]; Thimerosal results in increased cleavage of and results in increased activity of CASP3 protein
|
CTD |
PMID:12140745 PMID:15869795 PMID:16649253 PMID:17698513 PMID:17888894 PMID:23145070 PMID:27660204 PMID:30503815 More...
|
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648
|
|
G
|
Casp9
|
caspase 9
|
increases cleavage multiple interactions increases activity
|
ISO
|
Thimerosal results in increased cleavage of CASP9 protein Glutathione inhibits the reaction [Thimerosal results in increased activity of CASP9 protein] benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [Thimerosal results in increased cleavage of CASP9 protein]; BIRC5 mutant form promotes the reaction [Thimerosal results in increased cleavage of CASP9 protein]; BIRC5 protein inhibits the reaction [Thimerosal results in increased cleavage of CASP9 protein]; IGF1 protein inhibits the reaction [Thimerosal results in increased cleavage of CASP9 protein]; Thimerosal promotes the reaction [BIRC5 mutant form results in increased cleavage of CASP9 protein]; Thimerosal promotes the reaction [wortmannin results in increased cleavage of CASP9 protein]; wortmannin promotes the reaction [Thimerosal results in increased cleavage of CASP9 protein]
|
CTD |
PMID:12140745 PMID:15869795 PMID:23145070 |
|
Ensembl chr 5:154,109,046...154,126,626
|
|
G
|
Cat
|
catalase
|
multiple interactions
|
ISO
|
[Thimerosal co-treated with Aluminum Hydroxide] results in increased activity of CAT protein
|
CTD |
PMID:36411272 |
|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478
|
|
G
|
Cbl
|
Cbl proto-oncogene
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CBL mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:53,384,656...53,468,067
Ensembl chr 8:44,489,410...44,571,176
|
|
G
|
Cbx3
|
chromobox 3
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CBX3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:80,545,450...80,559,284
Ensembl chr 4:80,546,010...80,559,283 Ensembl chr 4:80,546,010...80,559,283
|
|
G
|
Cbx5
|
chromobox 5
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CBX5 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:136,203,827...136,254,575
Ensembl chr 7:134,331,335...134,375,022
|
|
G
|
Cbx7
|
chromobox 7
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CBX7 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:111,460,656...111,479,231
Ensembl chr 7:111,460,656...111,477,973
|
|
G
|
Cc2d2b
|
coiled-coil and C2 domain containing 2B
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CC2D2B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:239,561,506...239,655,771
Ensembl chr 1:239,561,987...239,682,416
|
|
G
|
Ccdc126
|
coiled-coil domain containing 126
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CCDC126 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:78,297,625...78,318,655
Ensembl chr 4:78,297,551...78,318,655
|
|
G
|
Ccdc183
|
coiled-coil domain containing 183
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CCDC183 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:8,428,784...8,438,948
Ensembl chr 3:8,428,787...8,437,194
|
|
G
|
Ccdc186
|
coiled-coil domain containing 186
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CCDC186 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:255,831,663...255,871,954
Ensembl chr 1:255,839,595...255,871,935
|
|
G
|
Ccdc66
|
coiled-coil domain containing 66
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CCDC66 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr16:2,662,125...2,694,031
Ensembl chr16:2,662,131...2,694,023
|
|
G
|
Ccdc71l
|
coiled-coil domain containing 71-like
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CCDC71L mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:48,960,020...48,964,112
Ensembl chr 6:48,960,191...48,960,841 Ensembl chr 6:48,960,191...48,960,841
|
|
G
|
Ccdc82
|
coiled-coil domain containing 82
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CCDC82 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:10,227,727...10,265,963
Ensembl chr 8:10,228,430...10,265,963
|
|
G
|
Ccdc85b
|
coiled-coil domain containing 85B
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CCDC85B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:202,763,645...202,764,660
Ensembl chr 1:202,763,631...202,764,703
|
|
G
|
Ccm2l
|
CCM2 like scaffold protein
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CCM2L mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:141,533,470...141,549,136
Ensembl chr 3:141,533,511...141,549,140
|
|
G
|
Ccn1
|
cellular communication network factor 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CCN1 mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
|
|
G
|
Ccnb1
|
cyclin B1
|
multiple interactions
|
ISO
|
Thimerosal results in increased expression of and results in increased activity of CCNB1 protein
|
CTD |
PMID:16649253 |
|
NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:31,912,193...31,921,172
|
|
G
|
Ccnd1
|
cyclin D1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CCND1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602
|
|
G
|
Ccnd2
|
cyclin D2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CCND2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:161,653,048...161,675,422
Ensembl chr 4:159,962,363...159,989,495
|
|
G
|
Ccnt1
|
cyclin T1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CCNT1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:129,687,146...129,718,080
Ensembl chr 7:129,691,209...129,717,871
|
|
G
|
Ccnt2
|
cyclin T2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CCNT2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr13:39,251,573...39,293,172
Ensembl chr13:39,251,573...39,292,019
|
|
G
|
Ccser1
|
coiled-coil serine-rich protein 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CCSER1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:90,153,873...91,391,441
Ensembl chr 4:90,292,780...91,388,786
|
|
G
|
Cct6b
|
chaperonin containing TCP1 subunit 6B
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CCT6B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:67,652,461...67,701,385
Ensembl chr10:67,652,546...67,701,284
|
|
G
|
Cd28
|
Cd28 molecule
|
affects response to substance
|
ISO
|
CD28 affects the susceptibility to Thimerosal
|
CTD |
PMID:15808517 |
|
NCBI chr 9:69,660,316...69,689,192
Ensembl chr 9:62,166,192...62,194,685
|
|
G
|
Cd40
|
CD40 molecule
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CD40 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:153,790,449...153,805,534
|
|
G
|
Cd6
|
Cd6 molecule
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CD6 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 1:207,442,873...207,481,703
Ensembl chr 1:207,442,877...207,481,634
|
|
G
|
Cd79b
|
CD79b molecule
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CD79B mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr10:91,739,134...91,742,312
Ensembl chr10:91,239,356...91,242,625
|
|
G
|
Cd81
|
Cd81 molecule
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CD81 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:207,665,274...207,681,094
Ensembl chr 1:198,241,484...198,251,660
|
|
G
|
Cd86
|
CD86 molecule
|
multiple interactions increases expression
|
ISO
|
Acetylcysteine inhibits the reaction [Thimerosal results in increased expression of CD86 protein]; Cysteine inhibits the reaction [Thimerosal results in increased expression of CD86 protein]; Glutathione inhibits the reaction [Thimerosal results in increased expression of CD86 protein]; Vitamin E inhibits the reaction [Thimerosal results in increased expression of CD86 protein]
|
CTD |
PMID:15737199 PMID:20417223 PMID:20457211 |
|
NCBI chr11:77,647,565...77,706,178
Ensembl chr11:64,163,828...64,200,818
|
|
G
|
Cd99
|
CD99 molecule (Xg blood group)
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CD99 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr20:54,418,239...54,422,882
|
|
G
|
Cdc20b
|
cell division cycle 20B
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CDC20B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:44,688,349...44,738,056
|
|
G
|
Cdc27
|
cell division cycle 27
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CDC27 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:89,400,720...89,449,816
Ensembl chr10:89,400,940...89,449,736
|
|
G
|
Cdc37l1
|
cell division cycle 37-like 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CDC37L1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:226,705,019...226,733,994
Ensembl chr 1:226,705,003...226,761,175
|
|
G
|
Cdc42se2
|
CDC42 small effector 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CDC42SE2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:38,836,549...38,905,056
Ensembl chr10:38,836,555...38,905,059 Ensembl chr 1:38,836,555...38,905,059
|
|
G
|
Cdca2
|
cell division cycle associated 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CDCA2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr15:46,071,360...46,117,524
Ensembl chr15:41,895,901...41,941,611
|
|
G
|
Cdh8
|
cadherin 8
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CDH8 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr19:5,494,552...5,901,950
Ensembl chr19:5,494,174...5,895,669
|
|
G
|
Cdhr1
|
cadherin-related family member 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CDHR1 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr16:12,863,696...12,883,579
Ensembl chr16:12,843,437...12,863,396
|
|
G
|
Cdk1
|
cyclin-dependent kinase 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CDK1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,266,248...19,281,408
|
|
G
|
Cdk14
|
cyclin-dependent kinase 14
|
affects expression
|
ISO
|
Thimerosal affects the expression of CDK14 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:28,666,416...29,258,865
Ensembl chr 4:28,666,843...29,258,861
|
|
G
|
Cdk16
|
cyclin-dependent kinase 16
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CDK16 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr X:4,046,330...4,057,825
Ensembl chr X:1,492,814...1,504,148
|
|
G
|
Cdk4
|
cyclin-dependent kinase 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CDK4 protein
|
CTD |
PMID:16649253 |
|
NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:62,883,105...62,942,403
|
|
G
|
Cdk6
|
cyclin-dependent kinase 6
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CDK6 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:31,592,384...31,784,732
Ensembl chr 4:30,646,460...30,829,634
|
|
G
|
Cdkn1c
|
cyclin-dependent kinase inhibitor 1C
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CDKN1C mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
|
|
G
|
Cdt1
|
chromatin licensing and DNA replication factor 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CDT1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659
|
|
G
|
Cenpn
|
centromere protein N
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CENPN mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr19:44,971,265...44,994,019
Ensembl chr19:44,968,308...44,994,012
|
|
G
|
Cenpq
|
centromere protein Q
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CENPQ mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:19,957,122...19,972,807
Ensembl chr 9:19,957,048...19,972,789
|
|
G
|
Cenpu
|
centromere protein U
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CENPU mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr16:52,448,446...52,471,662
Ensembl chr16:45,714,294...45,738,823
|
|
G
|
Cep126
|
centrosomal protein 126
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CEP126 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:5,200,576...5,267,740
Ensembl chr 8:5,218,509...5,267,467
|
|
G
|
Cep350
|
centrosomal protein 350
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CEP350 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr13:68,023,327...68,164,478
Ensembl chr13:68,026,891...68,165,214
|
|
G
|
Cep89
|
centrosomal protein 89
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CEP89 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:88,058,211...88,100,114
Ensembl chr 1:88,058,227...88,100,112
|
|
G
|
Cfap263
|
cilia and flagella associated protein 263
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CFAP263 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr19:9,503,062...9,522,957
Ensembl chr19:9,496,886...9,516,923
|
|
G
|
Cfap300
|
cilia and flagella associated protein 300
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CFAP300 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:5,180,180...5,198,840
Ensembl chr 8:5,180,675...5,198,807
|
|
G
|
Cfap44
|
cilia and flagella associated protein 44
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CFAP44 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr11:56,199,772...56,283,964
Ensembl chr11:56,201,049...56,283,986
|
|
G
|
Cfap96
|
cilia and flagella associated protein 96
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CFAP96 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr16:46,291,075...46,315,616
Ensembl chr16:46,291,311...46,315,625
|
|
G
|
Cfp
|
complement factor properdin
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CFP mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr X:3,715,551...3,721,113
Ensembl chr X:1,161,979...1,167,573
|
|
G
|
Cga
|
glycoprotein hormones, alpha polypeptide
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CGA mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 5:54,283,109...54,295,464
Ensembl chr 5:49,487,068...49,499,191
|
|
G
|
Chchd10
|
coiled-coil-helix-coiled-coil-helix domain containing 10
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CHCHD10 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr20:12,725,839...12,727,638
Ensembl chr20:12,725,842...12,732,763
|
|
G
|
Chd4
|
chromodomain helicase DNA binding protein 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CHD4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:157,898,503...157,931,632
Ensembl chr 4:157,899,391...157,931,541
|
|
G
|
Chd9
|
chromodomain helicase DNA binding protein 9
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CHD9 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr19:15,941,535...16,146,220
Ensembl chr19:15,942,687...16,164,556
|
|
G
|
Chmp5
|
charged multivesicular body protein 5
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CHMP5 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:60,877,369...60,894,512
Ensembl chr 5:56,081,343...56,098,529
|
|
G
|
Chn2
|
chimerin 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CHN2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:83,148,616...83,407,711
Ensembl chr 4:83,147,983...83,407,709
|
|
G
|
Chpt1
|
choline phosphotransferase 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CHPT1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:24,753,880...24,802,529
Ensembl chr 7:22,863,027...22,915,103
|
|
G
|
Cib2
|
calcium and integrin binding family member 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CIB2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:54,930,265...54,947,157
|
|
G
|
Cibar1
|
CBY1 interacting BAR domain containing 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CIBAR1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:25,613,993...25,632,440
Ensembl chr 5:25,614,033...25,632,489
|
|
G
|
Cilp2
|
cartilage intermediate layer protein 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CILP2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr16:19,539,755...19,547,191
Ensembl chr16:19,539,706...19,547,191
|
|
G
|
Cisd2
|
CDGSH iron sulfur domain 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CISD2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:223,828,937...223,853,768
Ensembl chr 2:223,828,937...223,868,946
|
|
G
|
Cited2
|
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CITED2 mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897
|
|
G
|
Clasp2
|
cytoplasmic linker associated protein 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CLASP2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:122,555,532...122,736,934
Ensembl chr 8:113,677,284...113,858,731
|
|
G
|
Clk4
|
CDC-like kinase 4
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CLK4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:35,523,382...35,541,387
Ensembl chr10:35,524,755...35,541,352
|
|
G
|
Clp1
|
cleavage factor polyribonucleotide kinase subunit 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CLP1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:69,806,774...69,818,633
Ensembl chr 3:69,806,778...69,810,421
|
|
G
|
Clu
|
clusterin
|
increases expression decreases expression
|
ISO
|
Thimerosal results in increased expression of CLU mRNA Thimerosal results in decreased expression of CLU mRNA
|
CTD |
PMID:16870260 PMID:27188386 |
|
NCBI chr15:44,336,619...44,375,861
Ensembl chr15:40,174,617...40,200,315
|
|
G
|
Cmip
|
c-Maf-inducing protein
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CMIP mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr19:45,304,597...45,510,653
Ensembl chr19:45,304,031...45,508,709
|
|
G
|
Cnfn
|
cornifelin
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CNFN mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:80,949,699...80,953,747
Ensembl chr 1:80,951,600...80,953,747
|
|
G
|
Cnot7
|
CCR4-NOT transcription complex, subunit 7
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CNOT7 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr16:51,775,416...51,794,581
Ensembl chr16:51,775,412...51,794,576
|
|
G
|
Cnot9
|
CCR4-NOT transcription complex subunit 9
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CNOT9 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:76,084,269...76,109,111
Ensembl chr 9:76,084,334...76,109,100
|
|
G
|
Cnpy2
|
canopy FGF signaling regulator 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CNPY2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:748,877...754,352
Ensembl chr 7:749,008...755,519
|
|
G
|
Cntnap2
|
contactin associated protein 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CNTNAP2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:75,109,358...77,366,258
Ensembl chr 4:74,109,472...76,362,027
|
|
G
|
Cobll1
|
cordon-bleu WH2 repeat protein-like 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of COBLL1 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 3:49,753,260...49,915,168
Ensembl chr 3:49,753,262...49,915,194
|
|
G
|
Cog3
|
component of oligomeric golgi complex 3
|
increases expression
|
ISO
|
Thimerosal results in increased expression of COG3 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr15:51,020,808...51,071,288
Ensembl chr15:51,020,813...51,070,570
|
|
G
|
Col22a1
|
collagen type XXII alpha 1 chain
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of COL22A1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:103,730,939...103,968,452
Ensembl chr 7:103,731,037...103,968,462
|
|
G
|
Col4a6
|
collagen type IV alpha 6 chain
|
increases expression
|
ISO
|
Thimerosal results in increased expression of COL4A6 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr X:104,766,463...105,117,499
Ensembl chr X:104,766,957...105,117,500
|
|
G
|
Col9a2
|
collagen type IX alpha 2 chain
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of COL9A2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:139,892,798...139,910,131
Ensembl chr 5:134,607,616...134,624,677
|
|
G
|
Cops7b
|
COP9 signalosome subunit 7B
|
increases expression
|
ISO
|
Thimerosal results in increased expression of COPS7B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:87,238,132...87,263,967
Ensembl chr 9:87,238,375...87,263,967
|
|
G
|
Cox15
|
cytochrome c oxidase assembly homolog COX15
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of COX15 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:242,605,588...242,622,279
Ensembl chr 1:242,605,588...242,622,261
|
|
G
|
Cox4i1
|
cytochrome c oxidase subunit 4i1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of COX4I1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr19:65,630,383...65,636,623
Ensembl chr19:48,721,199...48,727,921
|
|
G
|
Cpeb2
|
cytoplasmic polyadenylation element binding protein 2
|
multiple interactions increases expression
|
ISO
|
[NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CPEB2 mRNA Thimerosal results in increased expression of CPEB2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr14:71,999,958...72,056,012
Ensembl chr14:67,787,507...67,840,743
|
|
G
|
Cpeb3
|
cytoplasmic polyadenylation element binding protein 3
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CPEB3 mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr 1:244,161,690...244,343,765
Ensembl chr 1:234,751,733...234,931,560
|
|
G
|
Cpne3
|
copine 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CPNE3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:33,014,658...33,063,934
Ensembl chr 5:33,016,307...33,063,934
|
|
G
|
Cps1
|
carbamoyl-phosphate synthase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CPS1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033
|
|
G
|
Crcp
|
CGRP receptor component
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CRCP mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr12:26,623,968...26,659,756
Ensembl chr12:26,623,976...26,768,225
|
|
G
|
Creb1
|
cAMP responsive element binding protein 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CREB1 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:65,903,547...65,970,816
|
|
G
|
Crip3
|
cysteine-rich protein 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CRIP3 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 9:14,554,450...14,557,344
Ensembl chr 9:14,554,450...14,557,302
|
|
G
|
Cryab
|
crystallin, alpha B
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CRYAB mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr 8:59,989,885...59,995,532
Ensembl chr 8:51,093,441...51,099,157
|
|
G
|
Cs
|
citrate synthase
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CS mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421
|
|
G
|
Cspp1
|
centrosome and spindle pole associated protein 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CSPP1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:13,860,072...13,975,299
Ensembl chr 5:9,077,161...9,193,377
|
|
G
|
Ctdspl2
|
CTD small phosphatase like 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CTDSPL2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:108,915,263...108,970,620
Ensembl chr 3:108,915,280...108,967,227
|
|
G
|
Ctnna1
|
catenin alpha 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CTNNA1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr18:27,002,330...27,135,009
Ensembl chr18:26,728,485...26,860,910
|
|
G
|
Ctxn3
|
cortexin 3
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CTXN3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr18:50,930,244...50,940,642
Ensembl chr18:50,930,235...50,940,641
|
|
G
|
Cxhxorf38
|
similar to human chromosome X open reading frame 38
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CXORF38 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr X:10,128,070...10,150,904
Ensembl chr X:10,129,657...10,150,900
|
|
G
|
Cyb5r3
|
cytochrome b5 reductase 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of CYB5R3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:114,306,686...114,324,247
Ensembl chr 7:114,306,685...114,324,298
|
|
G
|
Cyb5r4
|
cytochrome b5 reductase 4
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CYB5R4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:87,975,596...88,048,356
Ensembl chr 8:87,981,116...88,045,832
|
|
G
|
Cyp39a1
|
cytochrome P450, family 39, subfamily a, polypeptide 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of CYP39A1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:24,727,817...24,804,060
Ensembl chr 9:17,230,455...17,306,775
|
|
G
|
Dact3
|
dishevelled-binding antagonist of beta-catenin 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of DACT3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:86,674,989...86,686,722
Ensembl chr 1:77,546,900...77,558,630
|
|
G
|
Dbh
|
dopamine beta-hydroxylase
|
multiple interactions
|
ISO
|
[Thimerosal co-treated with Aluminum Hydroxide] results in increased expression of DBH protein
|
CTD |
PMID:36411272 |
|
NCBI chr 3:30,886,313...30,903,313
Ensembl chr 3:10,488,260...10,505,248
|
|
G
|
Dbn1
|
drebrin 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of DBN1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984
|
|
G
|
Dcaf13
|
DDB1 and CUL4 associated factor 13
|
increases expression
|
ISO
|
Thimerosal results in increased expression of DCAF13 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:70,160,983...70,196,142
Ensembl chr 7:70,160,941...70,196,142
|
|
G
|
Dcaf16
|
DDB1 and CUL4 associated factor 16
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of DCAF16 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr14:65,449,631...65,450,015
|
|
G
|
Dcaf4
|
DDB1 and CUL4 associated factor 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of DCAF4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:103,154,847...103,180,992
Ensembl chr 6:103,154,867...103,180,982
|
|
G
|
Dcaf7
|
DDB1 and CUL4 associated factor 7
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of DCAF7 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:90,974,095...90,996,275
Ensembl chr10:90,974,095...90,996,275
|
|
G
|
Dcc
|
DCC netrin 1 receptor
|
increases expression
|
ISO
|
Thimerosal results in increased expression of DCC mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr18:67,144,272...68,248,159
Ensembl chr18:64,873,898...65,972,740
|
|
G
|
Dcun1d1
|
defective in cullin neddylation 1 domain containing 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of DCUN1D1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:118,721,275...118,772,606
Ensembl chr 2:118,721,822...118,772,602
|
|
G
|
Dcx
|
doublecortin
|
increases expression
|
ISO
|
Thimerosal results in increased expression of DCX mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr X:112,227,455...112,370,291
Ensembl chr X:107,430,767...107,507,476
|
|
G
|
Ddx39b
|
DExD-box helicase 39B
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of DDX39B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr20:3,547,702...3,585,064
Ensembl chr20:3,572,056...3,584,996
|
|
G
|
Ddx6
|
DEAD-box helicase 6
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of DDX6 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:44,931,127...44,967,773
Ensembl chr 8:44,931,974...44,964,405 Ensembl chr 8:44,931,974...44,964,405
|
|
G
|
Dennd1b
|
DENN domain containing 1B
|
increases expression
|
ISO
|
Thimerosal results in increased expression of DENND1B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr13:50,545,324...50,772,922
Ensembl chr13:50,545,836...50,770,601
|
|
G
|
Dexi
|
Dexi homolog
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of DEXI mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:5,126,021...5,138,746
Ensembl chr10:5,137,288...5,138,738
|
|
G
|
Dgat1
|
diacylglycerol O-acyltransferase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of DGAT1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:110,104,514...110,119,091
Ensembl chr 7:108,218,524...108,234,299
|
|
G
|
Dhcr24
|
24-dehydrocholesterol reductase
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of DHCR24 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:126,573,366...126,599,940
Ensembl chr 5:121,344,575...121,371,137
|
|
G
|
Dhcr7
|
7-dehydrocholesterol reductase
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of DHCR7 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
|
|
G
|
Dhrs1
|
dehydrogenase/reductase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of DHRS1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr15:29,236,522...29,243,807
Ensembl chr15:29,236,522...29,243,838
|
|
G
|
Dhx36
|
DEAH-box helicase 36
|
increases expression
|
ISO
|
Thimerosal results in increased expression of DHX36 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572
|
|
G
|
Dhx9
|
DExH-box helicase 9
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of DHX9 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr13:68,152,813...68,189,580
Ensembl chr13:65,602,323...65,639,069
|
|
G
|
Dkkl1
|
dickkopf like acrosomal protein 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of DKKL1 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 1:95,694,010...95,699,259
Ensembl chr 1:95,694,010...95,699,259
|
|
G
|
Dlg1
|
discs large MAGUK scaffold protein 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of DLG1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr11:82,416,853...82,607,797
Ensembl chr11:68,911,883...69,102,689
|
|
G
|
Dnajb1
|
DnaJ heat shock protein family (Hsp40) member B1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of DNAJB1 mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr19:41,427,453...41,431,141
Ensembl chr19:24,522,717...24,526,458
|
|
G
|
Dnajb4
|
DnaJ heat shock protein family (Hsp40) member B4
|
increases expression
|
ISO
|
Thimerosal results in increased expression of DNAJB4 mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089
|
|
G
|
Dnajc13
|
DnaJ heat shock protein family (Hsp40) member C13
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of DNAJC13 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:113,646,573...113,756,104
Ensembl chr 8:104,767,788...104,877,317
|
|
G
|
Dnajc4
|
DnaJ heat shock protein family (Hsp40) member C4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of DNAJC4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:204,178,189...204,182,412
Ensembl chr 1:204,178,191...204,182,387
|
|
G
|
Dnase1
|
deoxyribonuclease 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of DNASE1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:11,498,930...11,505,151
Ensembl chr10:11,498,931...11,501,869
|
|
G
|
Dnmt3a
|
DNA methyltransferase 3 alpha
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of DNMT3A mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:32,507,316...32,621,678
Ensembl chr 6:26,822,609...26,896,687
|
|
G
|
Dock11
|
dedicator of cytokinesis 11
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of DOCK11 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr X:119,997,523...120,180,643
Ensembl chr X:115,131,909...115,314,854
|
|
G
|
Dock4
|
dedicator of cytokinesis 4
|
increases expression
|
ISO
|
Thimerosal results in increased expression of DOCK4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:57,512,929...57,902,597
Ensembl chr 6:57,512,908...57,901,855
|
|
G
|
Dock6
|
dedicator of cytokinesis 6
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of DOCK6 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:28,618,523...28,670,741
Ensembl chr 8:20,342,089...20,394,552
|
|
G
|
Dst
|
dystonin
|
affects expression
|
ISO
|
Thimerosal affects the expression of DST mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:36,135,657...36,529,617
Ensembl chr 9:36,135,284...36,529,615
|
|
G
|
Dusp1
|
dual specificity phosphatase 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of DUSP1 mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr10:17,184,853...17,187,646
|
|
G
|
Dusp7
|
dual specificity phosphatase 7
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of DUSP7 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:115,888,091...115,895,126
Ensembl chr 8:107,008,528...107,016,404
|
|
G
|
Dynlt2b
|
dynein light chain Tctex-type 2B
|
increases expression
|
ISO
|
Thimerosal results in increased expression of DYNLT2B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr11:68,359,138...68,367,573
Ensembl chr11:68,358,263...68,367,499
|
|
G
|
Echdc2
|
enoyl CoA hydratase domain containing 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ECHDC2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:128,144,241...128,163,611
Ensembl chr 5:122,916,134...122,934,859
|
|
G
|
Ecrg4
|
ECRG4 augurin precursor
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ECRG4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:45,992,954...46,012,605
Ensembl chr 9:45,992,954...46,012,595
|
|
G
|
Ednrb
|
endothelin receptor type B
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of EDNRB mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr15:87,055,490...87,086,765
Ensembl chr15:80,643,043...80,672,115
|
|
G
|
Eea1
|
early endosome antigen 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of EEA1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:30,554,686...30,722,186
Ensembl chr 7:30,554,552...30,718,487
|
|
G
|
Eef1a2
|
eukaryotic translation elongation factor 1 alpha 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of EEF1A2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:168,265,893...168,275,071
Ensembl chr 3:168,195,357...168,275,071
|
|
G
|
Eef1akmt3
|
EEF1A lysine methyltransferase 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of EEF1AKMT3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:62,853,304...62,864,558
Ensembl chr 7:62,854,899...62,864,617
|
|
G
|
Efcab14
|
EF-hand calcium binding domain 14
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of EFCAB14 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:129,218,139...129,258,628
Ensembl chr 5:129,218,424...129,258,625
|
|
G
|
Egfl7
|
EGF-like-domain, multiple 7
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of EGFL7 mRNA
|
CTD |
PMID:24675092 PMID:27188386 |
|
NCBI chr 3:9,404,622...9,416,879
Ensembl chr 3:9,407,520...9,416,879
|
|
G
|
Egln1
|
egl-9 family hypoxia-inducible factor 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of EGLN1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr19:69,765,276...69,804,681
Ensembl chr19:52,869,486...52,907,777
|
|
G
|
Egln3
|
egl-9 family hypoxia-inducible factor 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of EGLN3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:77,385,549...77,411,015
Ensembl chr 6:71,650,297...71,675,766
|
|
G
|
Ehbp1
|
EH domain binding protein 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of EHBP1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr14:96,093,327...96,380,502
Ensembl chr14:96,093,327...96,345,332
|
|
G
|
Ehd4
|
EH-domain containing 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of EHD4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:127,511,973...127,575,856
Ensembl chr 3:107,058,958...107,122,002
|
|
G
|
Ehmt1
|
euchromatic histone lysine methyltransferase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of EHMT1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:7,580,680...7,729,046
Ensembl chr 3:7,580,683...7,729,007
|
|
G
|
Eif3f
|
eukaryotic translation initiation factor 3, subunit F
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of EIF3F mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:162,934,220...162,943,204
Ensembl chr 1:162,934,212...162,943,204
|
|
G
|
Eif4b
|
eukaryotic translation initiation factor 4B
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of EIF4B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:133,206,637...133,228,436
|
|
G
|
Eif4g1
|
eukaryotic translation initiation factor 4 gamma 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of EIF4G1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr11:93,726,322...93,746,387
Ensembl chr11:80,221,919...80,241,941
|
|
G
|
Eif5a2
|
eukaryotic translation initiation factor 5A2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of EIF5A2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:113,656,748...113,674,598
Ensembl chr 2:111,729,323...111,746,087
|
|
G
|
Elac1
|
elaC ribonuclease Z 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of ELAC1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr18:67,321,231...67,341,358
Ensembl chr18:67,323,583...67,340,936
|
|
G
|
Elmo1
|
engulfment and cell motility 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ELMO1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr17:44,286,495...44,822,668
Ensembl chr17:44,286,485...44,822,788
|
|
G
|
Eloa
|
elongin A
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ELOA mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:148,231,600...148,246,760
Ensembl chr 5:148,231,596...148,246,765
|
|
G
|
Eml5
|
EMAP like 5
|
increases expression
|
ISO
|
Thimerosal results in increased expression of EML5 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:118,046,655...118,175,831
Ensembl chr 6:118,046,655...118,175,831
|
|
G
|
Eno1
|
enolase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ENO1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:166,002,867...166,014,252
Ensembl chr 5:160,719,951...160,731,336 Ensembl chr 3:160,719,951...160,731,336
|
|
G
|
Eno2
|
enolase 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ENO2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:159,258,371...159,267,220
Ensembl chr 4:157,572,088...157,580,980
|
|
G
|
Eno3
|
enolase 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ENO3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:55,868,880...55,876,099
Ensembl chr10:55,366,975...55,375,921
|
|
G
|
Enpp5
|
ectonucleotide pyrophosphatase/phosphodiesterase family member 5
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ENPP5 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:16,910,187...16,917,633
Ensembl chr 9:16,910,831...16,917,480
|
|
G
|
Ep400
|
E1A binding protein p400
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of EP400 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr12:51,551,665...51,658,635
Ensembl chr12:45,891,916...45,998,861
|
|
G
|
Epb41l1
|
erythrocyte membrane protein band 4.1-like 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of EPB41L1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:144,929,195...145,052,723
Ensembl chr 3:144,984,640...145,052,721
|
|
G
|
Epb41l4a
|
erythrocyte membrane protein band 4.1 like 4A
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of EPB41L4A mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr18:25,405,461...25,615,392
Ensembl chr18:25,406,057...25,615,149
|
|
G
|
Epb41l5
|
erythrocyte membrane protein band 4.1 like 5
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of EPB41L5 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr13:33,221,705...33,321,400
Ensembl chr13:30,669,764...30,768,360
|
|
G
|
Epc1
|
enhancer of polycomb homolog 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of EPC1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr17:54,503,358...54,594,444
Ensembl chr17:54,503,358...54,594,425
|
|
G
|
Epcam
|
epithelial cell adhesion molecule
|
increases expression
|
ISO
|
Thimerosal results in increased expression of EPCAM mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127
|
|
G
|
Epop
|
elongin BC and polycomb repressive complex 2 associated protein
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of EPOP mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:82,624,392...82,625,912
Ensembl chr10:82,624,392...82,625,912
|
|
G
|
Eprs1
|
glutamyl-prolyl-tRNA synthetase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of EPRS1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr13:96,901,548...96,971,966
Ensembl chr13:96,901,575...96,971,966
|
|
G
|
Erc1
|
ELKS/RAB6-interacting/CAST family member 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ERC1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:152,763,664...153,055,724
Ensembl chr 4:152,767,419...153,055,639
|
|
G
|
Ercc2
|
ERCC excision repair 2, TFIIH core complex helicase subunit
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ERCC2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102
|
|
G
|
Ergic1
|
endoplasmic reticulum-golgi intermediate compartment 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ERGIC1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:16,531,192...16,626,974
Ensembl chr10:16,531,194...16,626,957
|
|
G
|
Ergic2
|
ERGIC and golgi 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of ERGIC2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:181,090,808...181,123,074
Ensembl chr 4:181,090,808...181,123,060
|
|
G
|
Esco1
|
establishment of sister chromatid cohesion N-acetyltransferase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ESCO1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr18:1,630,560...1,686,803
Ensembl chr18:1,631,954...1,686,942
|
|
G
|
Esco2
|
establishment of sister chromatid cohesion N-acetyltransferase 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ESCO2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr15:40,034,566...40,052,295
Ensembl chr15:40,034,568...40,055,306 Ensembl chr15:40,034,568...40,055,306
|
|
G
|
Esf1
|
ESF1 nucleolar pre-rRNA processing protein homolog
|
increases expression
|
ISO
|
Thimerosal results in increased expression of ESF1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:127,454,744...127,507,941
Ensembl chr 3:127,454,811...127,507,817
|
|
G
|
Etnk1
|
ethanolamine kinase 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of ETNK1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:176,126,056...176,170,325
Ensembl chr 4:176,126,180...176,193,770
|
|
G
|
Evc2
|
EvC ciliary complex subunit 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of EVC2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr14:73,366,832...73,454,539
Ensembl chr14:73,367,963...73,454,516
|
|
G
|
Evi5
|
ecotropic viral integration site 5
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of EVI5 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr14:2,020,524...2,166,593
Ensembl chr14:1,875,647...2,021,678
|
|
G
|
Exoc6
|
exocyst complex component 6
|
increases expression
|
ISO
|
Thimerosal results in increased expression of EXOC6 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:244,727,084...244,870,263
Ensembl chr 1:235,300,369...235,457,015
|
|
G
|
F12
|
coagulation factor XII
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of F12 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr17:9,212,819...9,220,664
Ensembl chr17:9,207,683...9,215,530
|
|
G
|
Fabp7
|
fatty acid binding protein 7
|
increases expression
|
ISO
|
Thimerosal results in increased expression of FABP7 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880
|
|
G
|
Fads1
|
fatty acid desaturase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of FADS1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:216,252,605...216,267,618
Ensembl chr 1:206,827,765...206,842,734
|
|
G
|
Fads2
|
fatty acid desaturase 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of FADS2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:216,132,277...216,172,190
Ensembl chr 1:206,708,783...206,748,789
|
|
G
|
Faf2
|
Fas associated factor family member 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of FAF2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr17:9,952,329...9,994,596
Ensembl chr17:9,947,220...9,989,485
|
|
G
|
Fah
|
fumarylacetoacetate hydrolase
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of FAH mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:147,957,931...147,980,708
Ensembl chr 1:138,548,834...138,571,505
|
|
G
|
Fam124b
|
family with sequence similarity 124 member B
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of FAM124B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:81,513,018...81,533,621
Ensembl chr 9:81,515,399...81,533,341
|
|
G
|
Fam135a
|
family with sequence similarity 135, member A
|
affects expression
|
ISO
|
Thimerosal affects the expression of FAM135A mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:26,420,116...26,500,803
Ensembl chr 9:26,420,528...26,500,717
|
|
G
|
Fam149a
|
family with sequence similarity 149, member A
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of FAM149A mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr16:46,855,377...46,914,553
Ensembl chr16:46,854,635...46,912,066
|
|
G
|
Fam162a
|
family with sequence similarity 162, member A
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of FAM162A mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr11:64,680,978...64,709,865
Ensembl chr11:64,680,323...64,711,239
|
|
G
|
Fam168b
|
family with sequence similarity 168, member B
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of FAM168B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:37,005,569...37,038,631
Ensembl chr 9:37,006,689...37,033,723
|
|
G
|
Fam234b
|
family with sequence similarity 234, member B
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of FAM234B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:168,048,313...168,124,017
Ensembl chr 4:168,048,396...168,097,338
|
|
G
|
Fam3c
|
FAM3 metabolism regulating signaling molecule C
|
increases expression
|
ISO
|
Thimerosal results in increased expression of FAM3C mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:50,839,929...50,887,276
Ensembl chr 4:50,838,818...50,888,078
|
|
G
|
Fam76b
|
family with sequence similarity 76, member B
|
increases expression
|
ISO
|
Thimerosal results in increased expression of FAM76B mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 8:10,689,396...10,711,847
Ensembl chr 8:10,688,963...10,711,861
|
|
G
|
Fam81b
|
family with sequence similarity 81, member B
|
increases expression
|
ISO
|
Thimerosal results in increased expression of FAM81B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:5,750,678...5,870,580
Ensembl chr 2:5,771,240...5,879,440
|
|
G
|
Fancf
|
FA complementation group F
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of FANCF mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr 1:101,449,120...101,451,936
Ensembl chr 1:101,450,389...101,451,923
|
|
G
|
Fas
|
Fas cell surface death receptor
|
increases expression
|
ISO
|
Thimerosal results in increased expression of FAS mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591
|
|
G
|
Fasn
|
fatty acid synthase
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of FASN mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,072,091...106,090,261
|
|
G
|
Fastkd2
|
FAST kinase domains 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of FASTKD2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:65,166,148...65,188,184
Ensembl chr 9:65,168,228...65,188,174
|
|
G
|
Fbln2
|
fibulin 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of FBLN2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:123,704,289...123,763,857
Ensembl chr 4:123,704,373...123,763,948
|
|
G
|
Fbn1
|
fibrillin 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of FBN1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:133,007,693...133,204,277
Ensembl chr 3:112,554,925...112,750,889
|
|
G
|
Fbxo3
|
F-box protein 3
|
increases expression
|
ISO
|
Thimerosal results in increased expression of FBXO3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:90,417,262...90,449,557
Ensembl chr 3:90,417,297...90,449,557
|
|
G
|
Fbxo7
|
F-box protein 7
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of FBXO7 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:19,696,951...19,725,180
Ensembl chr 7:17,809,231...17,837,530
|
|
G
|
Fbxo9
|
f-box protein 9
|
increases expression
|
ISO
|
Thimerosal results in increased expression of FBXO9 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:78,958,482...78,984,015
Ensembl chr 8:78,958,483...78,983,949
|
|
G
|
Fer
|
FER tyrosine kinase
|
increases expression
|
ISO
|
Thimerosal results in increased expression of FER mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:110,967,317...111,274,315
Ensembl chr 9:103,520,493...103,821,451
|
|
G
|
Fer1l4
|
fer-1-like family member 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of FER1L4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:144,536,099...144,571,634
Ensembl chr 3:144,536,099...144,571,634
|
|
G
|
Fgd6
|
FYVE, RhoGEF and PH domain containing 6
|
increases expression
|
ISO
|
Thimerosal results in increased expression of FGD6 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:28,597,609...28,712,908
Ensembl chr 7:28,597,609...28,712,456
|
|
G
|
Fgf11
|
fibroblast growth factor 11
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of FGF11 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:55,015,232...55,020,773
Ensembl chr10:54,517,077...54,522,062
|
|
G
|
Fgfbp3
|
fibroblast growth factor binding protein 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of FGFBP3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:234,644,023...234,646,028
Ensembl chr 1:234,644,019...234,646,547
|
|
G
|
Fgfr1op2
|
FGFR1 oncogene partner 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of FGFR1OP2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:179,491,602...179,512,630
Ensembl chr 4:179,491,599...179,512,630
|
|
G
|
Fgfr2
|
fibroblast growth factor receptor 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of FGFR2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:194,175,703...194,280,914
Ensembl chr 1:184,745,420...184,850,626
|
|
G
|
Fkbp10
|
FKBP prolyl isomerase 10
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of FKBP10 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:85,345,434...85,357,998
Ensembl chr10:85,346,126...85,427,330
|
|
G
|
Flcn
|
folliculin
|
multiple interactions
|
ISO
|
[NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FLCN mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:45,088,164...45,107,581
Ensembl chr10:44,588,624...44,607,769
|
|
G
|
Fmnl2
|
formin-like 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of FMNL2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:37,348,791...37,624,746
Ensembl chr 3:37,348,574...37,624,754
|
|
G
|
Fn1
|
fibronectin 1
|
increases secretion
|
ISO
|
Thimerosal results in increased secretion of FN1 protein
|
CTD |
PMID:24942245 |
|
NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:73,196,044...73,264,678
|
|
G
|
Fnbp4
|
formin binding protein 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of FNBP4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:76,733,012...76,763,077
Ensembl chr 3:76,733,027...76,763,079
|
|
G
|
Fndc10
|
fibronectin type III domain containing 10
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of FNDC10 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:171,581,960...171,584,519
Ensembl chr 5:166,300,122...166,310,326
|
|
G
|
Fndc11
|
fibronectin type III domain containing 11
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of FNDC11 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:168,330,607...168,333,111
Ensembl chr 3:168,330,602...168,334,617
|
|
G
|
Fndc4
|
fibronectin type III domain containing 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of FNDC4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:30,797,102...30,800,782
Ensembl chr 6:25,077,349...25,080,675
|
|
G
|
Folr1
|
folate receptor alpha
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of FOLR1 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667
|
|
G
|
Fos
|
Fos proto-oncogene, AP-1 transcription factor subunit
|
increases expression
|
ISO
|
Thimerosal results in increased expression of FOS mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036
|
|
G
|
Fosb
|
FosB proto-oncogene, AP-1 transcription factor subunit
|
increases expression
|
ISO
|
Thimerosal results in increased expression of FOSB mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:78,954,115...78,961,465
|
|
G
|
Foxc1
|
forkhead box C1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of FOXC1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr17:32,631,379...32,635,361
Ensembl chr17:32,633,142...32,634,803
|
|
G
|
Foxp2
|
forkhead box P2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of FOXP2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:43,133,827...43,712,442
Ensembl chr 4:43,133,912...43,711,683
|
|
G
|
Fra10ac1
|
FRA10A associated CGG repeat 1
|
multiple interactions
|
ISO
|
[NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FRA10AC1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:235,969,071...236,001,074
Ensembl chr 1:235,969,112...236,001,210
|
|
G
|
Frmd7
|
FERM domain containing 7
|
increases expression
|
ISO
|
Thimerosal results in increased expression of FRMD7 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr X:130,375,925...130,423,836
Ensembl chr X:130,377,227...130,423,771
|
|
G
|
Frmpd3
|
FERM and PDZ domain containing 3
|
increases expression
|
ISO
|
Thimerosal results in increased expression of FRMPD3 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr X:103,964,168...104,113,864
Ensembl chr X:104,043,194...104,111,968
|
|
G
|
Frs2
|
fibroblast growth factor receptor substrate 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of FRS2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:52,711,255...52,792,738
Ensembl chr 7:52,711,257...52,792,743
|
|
G
|
Fshb
|
follicle stimulating hormone subunit beta
|
increases expression
|
ISO
|
Thimerosal results in increased expression of FSHB mRNA; Thimerosal results in increased expression of FSHB protein
|
CTD |
PMID:24675092 |
|
NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:93,548,560...93,552,370
|
|
G
|
Fsip2
|
fibrous sheath-interacting protein 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of FSIP2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:67,962,345...68,032,866
Ensembl chr 3:67,962,360...68,032,868
|
|
G
|
Fut1
|
fucosyltransferase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of FUT1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:105,223,399...105,226,817
Ensembl chr 1:96,086,635...96,090,616
|
|
G
|
Fut11
|
fucosyltransferase 11
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of FUT11 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr15:3,598,768...3,602,328
Ensembl chr15:3,598,758...3,602,356
|
|
G
|
Fxyd6
|
FXYD domain-containing ion transport regulator 6
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of FXYD6 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:45,679,054...45,705,958
Ensembl chr 8:45,678,885...45,705,958
|
|
G
|
Fzd2
|
frizzled class receptor 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of FZD2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:88,061,988...88,063,898
Ensembl chr10:87,561,326...87,565,334
|
|
G
|
Fzd7
|
frizzled class receptor 7
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of FZD7 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:68,425,538...68,428,357
Ensembl chr 9:60,930,875...60,935,781
|
|
G
|
G3bp1
|
G3BP stress granule assembly factor 1
|
affects expression
|
ISO
|
Thimerosal affects the expression of G3BP1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:40,087,533...40,120,931
Ensembl chr10:39,586,864...39,620,268
|
|
G
|
G6pd
|
glucose-6-phosphate dehydrogenase
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of G6PD mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr X:157,352,364...157,372,144
Ensembl chr X:152,201,098...152,220,801
|
|
G
|
Gabra1
|
gamma-aminobutyric acid type A receptor subunit alpha 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of GABRA1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:27,096,731...27,152,563
Ensembl chr10:26,595,160...26,650,864
|
|
G
|
Gabrr1
|
gamma-aminobutyric acid type A receptor subunit rho 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of GABRR1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:47,524,151...47,561,228
Ensembl chr 5:47,524,151...47,561,228
|
|
G
|
Gadd45g
|
growth arrest and DNA-damage-inducible, gamma
|
increases expression
|
ISO
|
Thimerosal results in increased expression of GADD45G mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr17:13,528,606...13,530,351
Ensembl chr17:13,376,839...13,378,610
|
|
G
|
Gapvd1
|
GTPase activating protein and VPS9 domains 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of GAPVD1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:17,968,345...18,041,888
Ensembl chr 3:17,969,599...18,055,218
|
|
G
|
Garem1
|
GRB2 associated regulator of MAPK1 subtype 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of GAREM1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr18:12,420,169...12,585,323
Ensembl chr18:12,423,882...12,585,345
|
|
G
|
Garem2
|
GRB2 associated regulator of MAPK1 subtype 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of GAREM2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:26,228,965...26,255,576
Ensembl chr 6:26,230,048...26,241,762
|
|
G
|
Gas2l1
|
growth arrest-specific 2 like 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of GAS2L1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr14:84,169,398...84,175,514
Ensembl chr14:79,950,555...79,961,438
|
|
G
|
Gbe1
|
1,4-alpha-glucan branching enzyme 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of GBE1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr11:8,734,806...9,000,226
Ensembl chr11:8,734,820...9,000,210
|
|
G
|
Gemin4
|
gem (nuclear organelle) associated protein 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of GEMIN4 mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr10:61,560,172...61,571,765
Ensembl chr10:61,066,425...61,073,431 Ensembl chr10:61,066,425...61,073,431
|
|
G
|
Gfm1
|
G elongation factor, mitochondrial 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of GFM1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:151,700,573...151,745,477
Ensembl chr 2:151,700,564...151,745,471
|
|
G
|
Gh1
|
growth hormone 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of GH mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr10:91,727,883...91,729,860
Ensembl chr10:91,228,103...91,230,078
|
|
G
|
Ghrhr
|
growth hormone releasing hormone receptor
|
increases expression
|
ISO
|
Thimerosal results in increased expression of GHRHR mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 4:85,830,345...85,863,127
Ensembl chr 4:84,500,212...84,532,776
|
|
G
|
Gigyf1
|
GRB10 interacting GYF protein 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of GIGYF1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr12:19,166,070...19,181,570
Ensembl chr12:19,166,088...19,175,023
|
|
G
|
Gin1
|
gypsy retrotransposon integrase 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of GIN1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:98,293,596...98,315,155
Ensembl chr 9:98,293,597...98,315,848
|
|
G
|
Git2
|
GIT ArfGAP 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of GIT2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr12:41,829,717...41,872,621
Ensembl chr12:41,829,730...41,871,097
|
|
G
|
Gja4
|
gap junction protein, alpha 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of GJA4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:144,917,791...144,920,324
Ensembl chr 5:139,633,287...139,635,925
|
|
G
|
Glmp
|
glycosylated lysosomal membrane protein
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of GLMP mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:173,794,273...173,797,863
Ensembl chr 2:173,794,255...173,799,960
|
|
G
|
Gls
|
glutaminase
|
increases expression
|
ISO
|
Thimerosal results in increased expression of GLS mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:56,836,584...56,908,861
Ensembl chr 9:49,344,781...49,416,900
|
|
G
|
Gm2a
|
ganglioside GM2 activator
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of GM2A mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:39,219,221...39,231,756
Ensembl chr10:39,219,243...39,231,757
|
|
G
|
Gmds
|
GDP-mannose 4, 6-dehydratase
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of GMDS mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr17:32,304,029...32,830,708
Ensembl chr17:32,095,386...32,621,961
|
|
G
|
Gnal
|
G protein subunit alpha L
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of GNAL mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr18:60,622,311...60,762,599
Ensembl chr18:60,622,311...60,762,599
|
|
G
|
Gnb1
|
G protein subunit beta 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of GNB1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:171,357,778...171,424,489
Ensembl chr 5:166,075,629...166,142,124
|
|
G
|
Gng4
|
G protein subunit gamma 4
|
increases expression
|
ISO
|
Thimerosal results in increased expression of GNG4 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr17:86,448,708...86,497,560
Ensembl chr17:86,449,022...86,495,254
|
|
G
|
Gng7
|
G protein subunit gamma 7
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of GNG7 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:9,348,148...9,411,924
Ensembl chr 7:8,697,521...8,761,240
|
|
G
|
Gnrhr
|
gonadotropin releasing hormone receptor
|
increases expression
|
ISO
|
Thimerosal results in increased expression of GNRHR mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr14:21,856,871...21,874,861
Ensembl chr14:21,856,871...21,874,861
|
|
G
|
Gon4l
|
gon-4 like
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of GON4L mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:176,531,274...176,604,446
Ensembl chr 2:174,233,461...174,306,634
|
|
G
|
Gpcpd1
|
glycerophosphocholine phosphodiesterase 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of GPCPD1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:140,240,574...140,285,469
Ensembl chr 3:119,787,682...119,832,517
|
|
G
|
Gpi
|
glucose-6-phosphate isomerase
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of GPI mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086
|
|
G
|
Gpr135
|
G protein-coupled receptor 135
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of GPR135 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:90,627,533...90,630,661
Ensembl chr 6:90,629,178...90,630,551
|
|
G
|
Gpr22
|
G protein-coupled receptor 22
|
increases expression
|
ISO
|
Thimerosal results in increased expression of GPR22 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:48,309,619...48,317,864
Ensembl chr 6:48,310,505...48,317,486
|
|
G
|
Grem2
|
gremlin 2, DAN family BMP antagonist
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of GREM2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr13:89,310,897...89,403,856
Ensembl chr13:86,778,500...86,871,615
|
|
G
|
Grik2
|
glutamate ionotropic receptor kainate type subunit 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of GRIK2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375
|
|
G
|
Grik5
|
glutamate ionotropic receptor kainate type subunit 5
|
affects expression
|
ISO
|
Thimerosal affects the expression of GRIK5 protein
|
CTD |
PMID:15184908 |
|
NCBI chr 1:89,733,736...89,795,769
Ensembl chr 1:80,605,892...80,667,125
|
|
G
|
Grin1
|
glutamate ionotropic receptor NMDA type subunit 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of GRIN1 protein
|
CTD |
PMID:15184908 |
|
NCBI chr 3:28,501,836...28,528,754
Ensembl chr 3:8,103,680...8,130,603
|
|
G
|
Grin2b
|
glutamate ionotropic receptor NMDA type subunit 2B
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of GRIN2B protein
|
CTD |
PMID:15184908 |
|
NCBI chr 4:170,297,811...170,775,420
Ensembl chr 4:168,599,546...169,042,279
|
|
G
|
Grk3
|
G protein-coupled receptor kinase 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of GRK3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr12:49,285,228...49,395,803
Ensembl chr12:43,624,897...43,731,262
|
|
G
|
Gstm1
|
glutathione S-transferase mu 1
|
affects response to substance
|
ISO
|
GSTM1 affects the susceptibility to Thimerosal
|
CTD |
PMID:11007341 |
|
NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
|
|
G
|
Gstm2
|
glutathione S-transferase mu 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of GSTM2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
|
|
G
|
Gstt1
|
glutathione S-transferase theta 1
|
affects response to substance decreases expression
|
ISO
|
GSTT1 affects the susceptibility to Thimerosal Thimerosal results in decreased expression of GSTT1 mRNA
|
CTD |
PMID:11007341 PMID:27188386 |
|
NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
|
|
G
|
Gtf2a1
|
general transcription factor 2A subunit 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of GTF2A1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:110,488,891...110,521,502
Ensembl chr 6:110,488,931...110,521,511
|
|
G
|
Gtf2b
|
general transcription factor IIB
|
increases expression
|
ISO
|
Thimerosal results in increased expression of GTF2B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:231,767,317...231,785,626
Ensembl chr 2:231,767,238...231,785,651
|
|
G
|
Gtf2f1
|
general transcription factor IIF subunit 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of GTF2F1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:1,844,027...1,853,455
Ensembl chr 9:1,843,901...1,853,423
|
|
G
|
Guca1a
|
guanylate cyclase activator 1A
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of GUCA1A mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:13,588,988...13,598,566
Ensembl chr 9:13,588,525...13,598,565
|
|
G
|
Gulp1
|
GULP PTB domain containing engulfment adaptor 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of GULP1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:46,622,699...46,899,005
Ensembl chr 9:46,622,669...46,899,005
|
|
G
|
Gxylt1
|
glucoside xylosyltransferase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of GXYLT1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:124,400,896...124,434,682
Ensembl chr 7:124,400,896...124,434,699
|
|
G
|
H1f0
|
H1.0 linker histone
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of H1-0 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:112,473,280...112,475,140
Ensembl chr 7:110,592,208...110,594,694
|
|
G
|
H1f10
|
H1.10 linker histone
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of H1-10 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:120,440,515...120,441,578
Ensembl chr 4:120,440,870...120,441,448
|
|
G
|
H1f4
|
H1.4 linker histone, cluster member
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of H1-4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr17:41,486,574...41,487,355
Ensembl chr17:41,486,560...41,487,403
|
|
G
|
H4f3
|
H1.3 linker histone, cluster member
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of H1-3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr17:41,551,524...41,552,303
Ensembl chr17:41,529,667...41,552,334
|
|
G
|
Hacd2
|
3-hydroxyacyl-CoA dehydratase 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of HACD2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr11:79,175,470...79,268,975
Ensembl chr11:65,670,281...65,762,889
|
|
G
|
Hadha
|
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of HADHA mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:31,907,801...31,947,434
Ensembl chr 6:26,187,956...26,227,869
|
|
G
|
Hat1
|
histone acetyltransferase 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of HAT1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:56,217,344...56,265,021
Ensembl chr 3:56,217,342...56,275,517
|
|
G
|
Hbegf
|
heparin-binding EGF-like growth factor
|
increases expression
|
ISO
|
Thimerosal results in increased expression of HBEGF mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr18:28,380,337...28,390,220
Ensembl chr18:28,105,760...28,116,441
|
|
G
|
Hbs1l
|
HBS1-like translational GTPase
|
increases expression
|
ISO
|
Thimerosal results in increased expression of HBS1L mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:16,092,529...16,170,082
Ensembl chr 1:16,092,547...16,170,074
|
|
G
|
Hcfc1r1
|
host cell factor C1 regulator 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of HCFC1R1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:12,705,139...12,706,852
Ensembl chr10:12,705,077...12,706,850
|
|
G
|
Hdac4
|
histone deacetylase 4
|
multiple interactions increases expression
|
ISO EXP
|
MC1568 inhibits the reaction [Thimerosal results in increased expression of HDAC4 protein]
|
CTD |
PMID:27660204 |
|
NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164
|
|
G
|
Hdx
|
highly divergent homeobox
|
increases expression
|
ISO
|
Thimerosal results in increased expression of HDX mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr X:76,552,539...76,697,177
Ensembl chr X:76,560,665...76,869,972
|
|
G
|
Heatr1
|
HEAT repeat containing 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of HEATR1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr17:58,053,288...58,093,895
Ensembl chr17:58,051,700...58,093,948
|
|
G
|
Hebp1
|
heme binding protein 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of HEBP1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:167,974,316...168,003,854
Ensembl chr 4:167,974,319...168,003,854
|
|
G
|
Hectd1
|
HECT domain E3 ubiquitin protein ligase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of HECTD1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:74,916,803...75,003,408
Ensembl chr 6:69,181,436...69,268,053
|
|
G
|
Hectd2
|
HECT domain E3 ubiquitin protein ligase 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of HECTD2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:234,274,967...234,345,598
Ensembl chr 1:234,275,705...234,343,487
|
|
G
|
Hecw1
|
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of HECW1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr17:50,671,239...51,084,536
Ensembl chr17:50,670,954...51,080,720
|
|
G
|
Hells
|
helicase, lymphoid specific
|
increases expression
|
ISO
|
Thimerosal results in increased expression of HELLS mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:236,701,704...236,748,239
Ensembl chr 1:236,701,758...236,746,844
|
|
G
|
Henmt1
|
HEN methyltransferase 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of HENMT1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:196,585,732...196,603,700
Ensembl chr 2:196,586,797...196,599,738
|
|
G
|
Heph
|
hephaestin
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of HEPH mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr X:61,151,131...61,402,980
Ensembl chr X:61,296,345...61,402,980
|
|
G
|
Hes1
|
hes family bHLH transcription factor 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of HES1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr11:84,210,632...84,213,045
Ensembl chr11:70,705,764...70,708,192
|
|
G
|
Hes3
|
hes family bHLH transcription factor 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of HES3 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 5:162,793,611...162,799,578
Ensembl chr 5:162,794,367...162,796,261
|
|
G
|
Hif3a
|
hypoxia inducible factor 3 subunit alpha
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of HIF3A mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:77,718,110...77,750,448
Ensembl chr 1:77,722,471...77,749,758
|
|
G
|
Hip1
|
huntingtin interacting protein 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of HIP1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr12:21,133,364...21,267,796
Ensembl chr12:21,133,406...21,267,725
|
|
G
|
Hipk2
|
homeodomain interacting protein kinase 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of HIPK2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:68,399,358...68,586,404
Ensembl chr 4:67,440,501...67,619,223
|
|
G
|
Hk1
|
hexokinase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of HK1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr20:30,773,222...30,874,814
Ensembl chr20:30,230,486...30,332,131
|
|
G
|
Hk2
|
hexokinase 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of HK2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:116,792,258...116,841,275
Ensembl chr 4:115,234,509...115,283,530
|
|
G
|
Hmga1
|
high mobility group AT-hook 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of HMGA1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr20:5,612,902...5,620,596
Ensembl chr20:5,611,694...5,618,752
|
|
G
|
Hmgb1
|
high mobility group box 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of HMGB1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr12:11,009,236...11,015,941
Ensembl chr12:5,901,586...5,978,565 Ensembl chr16:5,901,586...5,978,565
|
|
G
|
Hmgn5
|
high mobility group nucleosome binding domain 5
|
increases expression
|
ISO
|
Thimerosal results in increased expression of HMGN5 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr X:74,085,871...74,094,488
Ensembl chr X:74,085,875...74,094,441 Ensembl chr 1:74,085,875...74,094,441
|
|
G
|
Hmox1
|
heme oxygenase 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of HMOX1 mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079
|
|
G
|
Hnrnpa0
|
heterogeneous nuclear ribonucleoprotein A0
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of HNRNPA0 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr17:6,507,728...6,510,385
Ensembl chr17:6,507,275...6,509,375
|
|
G
|
Hnrnpul2
|
heterogeneous nuclear ribonucleoprotein U-like 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of HNRNPUL2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:205,713,431...205,725,553
Ensembl chr 1:205,711,886...205,725,553
|
|
G
|
Hsd17b6
|
hydroxysteroid (17-beta) dehydrogenase 6
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of HSD17B6 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:422,466...442,008
Ensembl chr 7:422,480...442,425
|
|
G
|
Hsf2
|
heat shock transcription factor 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of HSF2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr20:36,819,864...36,847,490
Ensembl chr20:36,819,864...36,850,174
|
|
G
|
Hsp90ab1
|
heat shock protein 90 alpha family class B member 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of HSP90AB1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:15,433,691...15,438,488
|
|
G
|
Hspa13
|
heat shock protein family A (Hsp70) member 13
|
increases expression
|
ISO
|
Thimerosal results in increased expression of HSPA13 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr11:14,375,669...14,389,853
Ensembl chr11:14,373,275...14,389,895
|
|
G
|
Hspa1a
|
heat shock protein family A (Hsp70) member 1A
|
increases expression decreases expression
|
ISO
|
Thimerosal results in increased expression of HSPA1A mRNA Thimerosal results in decreased expression of HSPA1A mRNA
|
CTD |
PMID:16870260 PMID:24675092 |
|
NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,856,006...3,873,227
|
|
G
|
Hspa1b
|
heat shock protein family A (Hsp70) member 1B
|
increases expression
|
ISO
|
Thimerosal results in increased expression of HSPA1B mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,856,006...3,873,240 Ensembl chr20:3,856,006...3,873,240
|
|
G
|
Hspa1l
|
heat shock protein family A (Hsp70) member 1 like
|
increases expression
|
ISO
|
Thimerosal results in increased expression of HSPA1L mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr20:3,853,496...3,860,223
Ensembl chr20:3,848,843...3,855,571
|
|
G
|
Hspa4l
|
heat shock protein family A (Hsp70) member 4 like
|
increases expression
|
ISO
|
Thimerosal results in increased expression of HSPA4L mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:123,740,384...123,793,088
Ensembl chr 2:123,740,384...123,793,084
|
|
G
|
Hspa6l-ps1
|
heat shock protein family A (Hsp70) member 6 like, pseudogene 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of HSPA6 mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr13:85,805,911...85,807,052
|
|
G
|
Hspb1
|
heat shock protein family B (small) member 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of HSPB1 mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr12:26,430,640...26,432,301
Ensembl chr12:20,794,028...20,795,743
|
|
G
|
Htatsf1
|
HIV-1 Tat specific factor 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of HTATSF1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr X:134,935,426...134,949,607
Ensembl chr X:134,935,426...134,949,607
|
|
G
|
Htr2c
|
5-hydroxytryptamine receptor 2C
|
increases expression
|
ISO
|
Thimerosal results in increased expression of HTR2C mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr X:110,640,777...110,870,288
Ensembl chr X:110,641,153...110,870,287
|
|
G
|
Hyls1
|
HYLS1, centriolar and ciliogenesis associated
|
increases expression
|
ISO
|
Thimerosal results in increased expression of HYLS1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:33,912,692...33,921,760
Ensembl chr 8:33,912,692...33,921,760
|
|
G
|
Ier5l
|
immediate early response 5-like
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of IER5L mRNA
|
CTD |
PMID:24675092 PMID:27188386 |
|
NCBI chr 3:34,141,866...34,143,457
Ensembl chr 3:13,744,078...13,745,647
|
|
G
|
Ifng
|
interferon gamma
|
affects response to substance multiple interactions
|
ISO
|
IFNG affects the susceptibility to Thimerosal Glutathione inhibits the reaction [Thimerosal inhibits the reaction [Lipopolysaccharides results in increased secretion of IFNG protein]]; Thimerosal inhibits the reaction [Lipopolysaccharides results in increased secretion of IFNG protein]
|
CTD |
PMID:15808517 PMID:17079650 |
|
NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375
|
|
G
|
Ift80
|
intraflagellar transport 80
|
increases expression
|
ISO
|
Thimerosal results in increased expression of IFT80 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:153,144,707...153,240,024
Ensembl chr 2:153,145,795...153,240,024
|
|
G
|
Igdcc3
|
immunoglobulin superfamily, DCC subclass, member 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of IGDCC3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:65,661,165...65,707,961
Ensembl chr 8:65,661,196...65,707,959
|
|
G
|
Igf1
|
insulin-like growth factor 1
|
multiple interactions
|
ISO
|
Thimerosal affects the reaction [IGF1 protein results in increased activity of MTR protein] IGF1 protein inhibits the reaction [Thimerosal results in decreased expression of BIRC5 protein]; IGF1 protein inhibits the reaction [Thimerosal results in increased cleavage of CASP3 protein]; IGF1 protein inhibits the reaction [Thimerosal results in increased cleavage of CASP9 protein]
|
CTD |
PMID:14745455 PMID:23145070 |
|
NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:22,282,930...22,359,296
|
|
G
|
Igf2bp3
|
insulin-like growth factor 2 mRNA binding protein 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of IGF2BP3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:78,060,494...78,195,007
Ensembl chr 4:78,060,494...78,194,865
|
|
G
|
Igfbp2
|
insulin-like growth factor binding protein 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of IGFBP2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937
|
|
G
|
Igfbp5
|
insulin-like growth factor binding protein 5
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of IGFBP5 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
|
|
G
|
Iglon5
|
IgLON family member 5
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of IGLON5 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:93,880,906...93,898,929
Ensembl chr 1:93,881,991...93,898,754
|
|
G
|
Ikzf1
|
IKAROS family zinc finger 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of IKZF1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr14:90,468,696...90,556,522
Ensembl chr14:86,255,065...86,342,416
|
|
G
|
Il13
|
interleukin 13
|
multiple interactions
|
ISO
|
[Thimerosal co-treated with Lipopolysaccharides] results in increased secretion of IL13 protein; Glutathione inhibits the reaction [[Thimerosal co-treated with Lipopolysaccharides] results in increased secretion of IL13 protein]
|
CTD |
PMID:17079650 |
|
NCBI chr10:38,290,926...38,293,483
Ensembl chr10:37,790,130...37,792,737
|
|
G
|
Il13ra1
|
interleukin 13 receptor subunit alpha 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of IL13RA1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr X:120,213,670...120,294,777
Ensembl chr X:115,348,860...115,408,681 Ensembl chr11:115,348,860...115,408,681
|
|
G
|
Il17ra
|
interleukin 17 receptor A
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of IL17RA mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:153,667,534...153,690,174
Ensembl chr 4:153,667,534...153,690,174
|
|
G
|
Il27ra
|
interleukin 27 receptor subunit alpha
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of IL27RA mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr19:24,109,963...24,121,977
Ensembl chr19:24,109,972...24,121,938
|
|
G
|
Il5
|
interleukin 5
|
multiple interactions
|
ISO
|
[Thimerosal co-treated with Lipopolysaccharides] results in increased secretion of IL5 protein
|
CTD |
PMID:17079650 |
|
NCBI chr10:38,375,132...38,378,003
Ensembl chr10:37,874,342...37,877,213
|
|
G
|
Il6
|
interleukin 6
|
affects response to substance multiple interactions
|
ISO
|
IL6 affects the susceptibility to Thimerosal Glutathione inhibits the reaction [Thimerosal inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]]; Thimerosal inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
|
CTD |
PMID:15808517 PMID:17079650 |
|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178
|
|
G
|
Ilf3
|
interleukin enhancer binding factor 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ILF3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:19,922,409...19,960,495
Ensembl chr 8:19,922,460...19,960,350
|
|
G
|
Ilrun
|
inflammation and lipid regulator with UBA-like and NBR1-like domains
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ILRUN mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr20:5,809,931...5,876,197
Ensembl chr20:5,809,936...5,876,012
|
|
G
|
Immp1l
|
inner mitochondrial membrane peptidase subunit 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of IMMP1L mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:92,385,329...92,449,559
Ensembl chr 3:92,385,379...92,452,313
|
|
G
|
Inafm1
|
InaF-motif containing 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of INAFM1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:86,104,970...86,106,454
|
|
G
|
Ing3
|
inhibitor of growth family, member 3
|
increases expression
|
ISO
|
Thimerosal results in increased expression of ING3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:51,439,218...51,469,502
Ensembl chr 4:50,477,962...50,503,715
|
|
G
|
Ino80d
|
INO80 complex subunit D
|
increases expression
|
ISO
|
Thimerosal results in increased expression of INO80D mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:64,447,075...64,514,013
Ensembl chr 9:64,457,165...64,515,242
|
|
G
|
Insig1
|
insulin induced gene 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of INSIG1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:8,049,339...8,057,812
Ensembl chr 4:7,315,495...7,323,952
|
|
G
|
Ints10
|
integrator complex subunit 10
|
increases expression
|
ISO
|
Thimerosal results in increased expression of INTS10 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr16:20,915,223...20,947,146
Ensembl chr16:20,916,082...20,967,610
|
|
G
|
Ints14
|
integrator complex subunit 14
|
increases expression
|
ISO
|
Thimerosal results in increased expression of INTS14 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:65,475,788...65,500,807
Ensembl chr 8:65,475,910...65,500,804
|
|
G
|
Ints6
|
integrator complex subunit 6
|
increases expression
|
ISO
|
Thimerosal results in increased expression of INTS6 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr15:36,908,966...37,048,043
Ensembl chr15:36,933,724...37,021,527
|
|
G
|
Iqgap1
|
IQ motif containing GTPase activating protein 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of IQGAP1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755
|
|
G
|
Irag1
|
inositol 1,4,5-triphosphate receptor associated 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of IRAG1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:164,981,716...165,094,232
Ensembl chr 1:164,981,716...165,094,176
|
|
G
|
Irf2bp2
|
interferon regulatory factor 2 binding protein 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of IRF2BP2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr19:71,456,689...71,462,368
Ensembl chr19:54,560,128...54,566,642
|
|
G
|
Isyna1
|
inositol-3-phosphate synthase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ISYNA1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr16:18,839,143...18,841,979
Ensembl chr16:18,839,145...18,841,979
|
|
G
|
Itpr3
|
inositol 1,4,5-trisphosphate receptor, type 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ITPR3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr20:5,136,968...5,202,339
Ensembl chr20:5,136,441...5,202,337
|
|
G
|
Itprid2
|
ITPR interacting domain containing 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ITPRID2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:64,536,707...64,573,978
Ensembl chr 3:64,536,707...64,573,978
|
|
G
|
Itpripl1
|
ITPRIP like 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ITPRIPL1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:134,858,316...134,861,241
Ensembl chr 3:114,402,270...114,414,497
|
|
G
|
Itpripl2
|
ITPRIP like 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ITPRIPL2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:172,801,152...172,803,047
Ensembl chr 1:172,796,849...172,802,950
|
|
G
|
Itsn2
|
intersectin 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ITSN2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:27,616,645...27,727,373
Ensembl chr 6:27,600,406...27,727,124
|
|
G
|
Iws1
|
interacts with SUPT6H, CTD assembly factor 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of IWS1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr18:23,695,496...23,737,363
Ensembl chr18:23,695,425...23,736,172
|
|
G
|
Jmjd1c
|
jumonji domain containing 1C
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of JMJD1C mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr20:21,332,147...21,494,220
Ensembl chr20:21,332,147...21,463,122
|
|
G
|
Jph3
|
junctophilin 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of JPH3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr19:66,702,497...66,763,948
Ensembl chr19:49,793,092...49,855,338
|
|
G
|
Jun
|
Jun proto-oncogene, AP-1 transcription factor subunit
|
increases expression
|
ISO
|
Thimerosal results in increased expression of JUN mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656
|
|
G
|
Jund
|
JunD proto-oncogene, AP-1 transcription factor subunit
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of JUND mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr16:18,768,093...18,769,771
Ensembl chr16:18,734,122...18,735,799
|
|
G
|
Kansl1l
|
KAT8 regulatory NSL complex subunit 1-like
|
increases expression
|
ISO
|
Thimerosal results in increased expression of KANSL1L mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr 9:68,211,151...68,316,992
Ensembl chr 9:68,211,189...68,300,222
|
|
G
|
Kat2b
|
lysine acetyltransferase 2B
|
increases expression
|
ISO
|
Thimerosal results in increased expression of KAT2B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:6,799,101...6,903,616
Ensembl chr 9:6,562,288...6,667,064
|
|
G
|
Kat6a
|
lysine acetyltransferase 6A
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of KAT6A mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr16:75,787,411...75,868,584
Ensembl chr16:69,084,914...69,163,606
|
|
G
|
Kat8
|
lysine acetyltransferase 8
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of KAT8 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:191,954,827...191,967,107
Ensembl chr 1:182,515,327...182,536,633
|
|
G
|
Kbtbd2
|
kelch repeat and BTB domain containing 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of KBTBD2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:86,027,947...86,050,266
Ensembl chr 4:86,027,947...86,050,211
|
|
G
|
Kbtbd8
|
kelch repeat and BTB domain containing 8
|
increases expression
|
ISO
|
Thimerosal results in increased expression of KBTBD8 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:127,675,967...127,688,785
Ensembl chr 4:127,676,141...127,687,697
|
|
G
|
Kcnb2
|
potassium voltage-gated channel subfamily B member 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of KCNB2 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 5:3,567,012...4,028,564
Ensembl chr 5:3,569,685...4,028,599
|
|
G
|
Kcnip3
|
potassium voltage-gated channel interacting protein 3
|
multiple interactions
|
ISO
|
[SOD1 protein mutant form results in increased susceptibility to Thimerosal] which results in increased acetylation of and results in increased ubiquitination of KCNIP3 protein; [SOD1 protein results in increased susceptibility to Thimerosal] which results in decreased expression of KCNIP3 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[SOD1 protein results in increased susceptibility to Thimerosal] which results in decreased expression of KCNIP3 protein]; Resveratrol inhibits the reaction [[SOD1 protein mutant form results in increased susceptibility to Thimerosal] which results in increased acetylation of and results in increased ubiquitination of KCNIP3 protein]; Resveratrol inhibits the reaction [[SOD1 protein results in increased susceptibility to Thimerosal] which results in decreased expression of KCNIP3 protein]; SIRT1 protein affects the reaction [Resveratrol inhibits the reaction [[SOD1 protein results in increased susceptibility to Thimerosal] which results in decreased expression of KCNIP3 protein]]
|
CTD |
PMID:30503815 |
|
NCBI chr 3:114,677,027...114,742,923
Ensembl chr 3:114,677,030...114,743,556
|
|
G
|
Kcnrg
|
potassium channel regulator
|
increases expression
|
ISO
|
Thimerosal results in increased expression of KCNRG mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr15:35,774,456...35,779,409
Ensembl chr15:35,774,326...35,779,415
|
|
G
|
Kdelr1
|
KDEL endoplasmic reticulum protein retention receptor 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of KDELR1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:105,483,598...105,494,587
Ensembl chr 1:96,347,150...96,358,157
|
|
G
|
Kdm4b
|
lysine demethylase 4B
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of KDM4B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:1,158,737...1,237,233
Ensembl chr 9:1,158,752...1,236,543
|
|
G
|
Kdm6a
|
lysine demethylase 6A
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of KDM6A mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr X:4,337,466...4,477,100
Ensembl chr X:4,337,750...4,477,062
|
|
G
|
Khk
|
ketohexokinase
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of KHK mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:25,445,298...25,455,834
Ensembl chr 6:25,445,300...25,455,717
|
|
G
|
Kif1a
|
kinesin family member 1A
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of KIF1A mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:93,563,033...93,647,412
Ensembl chr 9:93,563,045...93,647,480
|
|
G
|
Kif21b
|
kinesin family member 21B
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of KIF21B mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr13:47,576,129...47,626,112
Ensembl chr13:47,576,160...47,626,127
|
|
G
|
Kif22
|
kinesin family member 22
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of KIF22 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 1:181,635,347...181,650,351
Ensembl chr 1:181,635,183...181,650,401
|
|
G
|
Kiss1r
|
KISS1 receptor
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of KISS1R mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:9,785,135...9,790,283
Ensembl chr 7:9,785,135...9,788,793
|
|
G
|
Klf12
|
KLF transcription factor 12
|
increases expression
|
ISO
|
Thimerosal results in increased expression of KLF12 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr15:76,628,778...77,062,000
Ensembl chr15:76,637,654...77,062,056
|
|
G
|
Klf13
|
KLF transcription factor 13
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of KLF13 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:126,917,671...126,948,436
Ensembl chr 1:117,503,602...117,551,227
|
|
G
|
Klf15
|
KLF transcription factor 15
|
increases expression
|
ISO
|
Thimerosal results in increased expression of KLF15 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:124,522,652...124,535,613
Ensembl chr 4:122,965,807...122,978,374
|
|
G
|
Klf4
|
KLF transcription factor 4
|
increases expression
|
ISO
|
Thimerosal results in increased expression of KLF4 mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
|
|
G
|
Klhdc10
|
kelch domain containing 10
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of KLHDC10 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:59,021,300...59,079,118
Ensembl chr 4:59,021,310...59,074,941
|
|
G
|
Klhl24
|
kelch-like family member 24
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of KLHL24 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr11:94,348,024...94,382,085
Ensembl chr11:80,846,755...80,877,636
|
|
G
|
Klhl3
|
kelch-like family member 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of KLHL3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr17:6,523,089...6,645,971
Ensembl chr17:6,521,912...6,642,154
|
|
G
|
Klhl41
|
kelch-like family member 41
|
increases expression
|
ISO
|
Thimerosal results in increased expression of KLHL41 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:54,434,291...54,447,415
Ensembl chr 3:54,434,234...54,449,222
|
|
G
|
Kmt2a
|
lysine methyltransferase 2A
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of KMT2A mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:54,013,547...54,089,219
Ensembl chr 8:45,118,814...45,193,181
|
|
G
|
Knl1
|
kinetochore scaffold 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of KNL1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:126,483,498...126,545,774
Ensembl chr 3:106,029,661...106,091,915
|
|
G
|
Kras
|
KRAS proto-oncogene, GTPase
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of KRAS mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:179,916,255...179,949,613
|
|
G
|
Krcc1
|
lysine-rich coiled-coil 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of KRCC1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:103,261,642...103,274,672
Ensembl chr 4:103,261,536...103,277,156
|
|
G
|
Krr1
|
KRR1, small subunit processome component homolog
|
increases expression
|
ISO
|
Thimerosal results in increased expression of KRR1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:47,475,557...47,486,996
Ensembl chr 7:47,475,557...47,486,985
|
|
G
|
Larp1b
|
La ribonucleoprotein 1B
|
increases expression
|
ISO
|
Thimerosal results in increased expression of LARP1B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:123,936,057...123,969,254
Ensembl chr 2:123,935,983...123,968,896
|
|
G
|
Larp4
|
La ribonucleoprotein 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of LARP4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:131,104,470...131,152,692
Ensembl chr 7:131,101,564...131,150,811
|
|
G
|
Larp7
|
La ribonucleoprotein 7, transcriptional regulator
|
increases expression
|
ISO
|
Thimerosal results in increased expression of LARP7 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:218,672,145...218,687,332
Ensembl chr 2:215,997,649...216,012,865
|
|
G
|
Lars1
|
leucyl-tRNA synthetase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of LARS1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr18:34,201,555...34,256,003
Ensembl chr18:34,201,549...34,255,931
|
|
G
|
Lcorl
|
ligand dependent nuclear receptor corepressor-like
|
increases expression
|
ISO
|
Thimerosal results in increased expression of LCORL mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr14:69,482,919...69,620,269
Ensembl chr14:65,271,135...65,404,174
|
|
G
|
Ldha
|
lactate dehydrogenase A
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of LDHA mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:97,366,021...97,433,472
|
|
G
|
Lgals3bp
|
galectin 3 binding protein
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of LGALS3BP mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:103,619,912...103,629,251
Ensembl chr10:103,619,908...103,629,256
|
|
G
|
Lgalsl
|
galectin-like
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of LGALSL mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr14:94,996,991...95,004,499
Ensembl chr14:94,996,990...95,004,980
|
|
G
|
Lgr5
|
leucine rich repeat containing G protein coupled receptor 5
|
increases expression
|
ISO
|
Thimerosal results in increased expression of LGR5 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 7:51,087,059...51,221,882
Ensembl chr 7:51,088,239...51,222,446
|
|
G
|
Lgr6
|
leucine-rich repeat-containing G protein-coupled receptor 6
|
increases expression
|
ISO
|
Thimerosal results in increased expression of LGR6 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr13:46,424,382...46,544,074
Ensembl chr13:46,424,383...46,543,945
|
|
G
|
Lhb
|
luteinizing hormone subunit beta
|
increases expression
|
ISO
|
Thimerosal results in increased expression of LHB mRNA; Thimerosal results in increased expression of LHB protein
|
CTD |
PMID:24675092 |
|
NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
|
|
G
|
Lhx9
|
LIM homeobox 9
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of LHX9 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr13:50,389,052...50,409,947
Ensembl chr13:50,389,738...50,410,806
|
|
G
|
Lima1
|
LIM domain and actin binding 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of LIMA1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:130,901,717...131,001,512
Ensembl chr 7:130,901,717...131,001,473
|
|
G
|
Lims1
|
LIM zinc finger domain containing 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of LIMS1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr20:26,851,364...26,961,607
Ensembl chr20:26,309,895...26,418,500
|
|
G
|
Lin7c
|
lin-7 homolog C, crumbs cell polarity complex component
|
increases expression
|
ISO
|
Thimerosal results in increased expression of LIN7C mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:96,406,800...96,417,779
Ensembl chr 3:96,406,813...96,417,728
|
|
G
|
Lin9
|
lin-9 DREAM MuvB core complex component
|
increases expression
|
ISO
|
Thimerosal results in increased expression of LIN9 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr13:92,374,612...92,419,664
Ensembl chr13:92,374,593...92,419,654 Ensembl chr14:92,374,593...92,419,654
|
|
G
|
Litaf
|
lipopolysaccharide-induced TNF factor
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of LITAF mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:5,163,258...5,199,930
Ensembl chr10:4,625,552...4,692,763
|
|
G
|
Lix1l
|
limb and CNS expressed 1 like
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of LIX1L mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:184,136,018...184,161,918
Ensembl chr 2:184,136,038...184,161,916
|
|
G
|
Lmbrd2
|
LMBR1 domain containing 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of LMBRD2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:58,189,558...58,251,565
Ensembl chr 2:58,189,558...58,247,076
|
|
G
|
Lmf1
|
lipase maturation factor 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of LMF1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:14,597,726...14,684,071
Ensembl chr10:14,597,594...14,684,119
|
|
G
|
Lnpep
|
leucyl and cystinyl aminopeptidase
|
multiple interactions
|
ISO
|
[NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of LNPEP mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:58,258,642...58,355,532
Ensembl chr 1:58,258,642...58,354,544
|
|
G
|
Lpcat1
|
lysophosphatidylcholine acyltransferase 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of LPCAT1 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 1:31,594,621...31,644,946
Ensembl chr 1:29,766,071...29,816,401
|
|
G
|
Lpgat1
|
lysophosphatidylglycerol acyltransferase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of LPGAT1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr13:103,294,622...103,365,372
Ensembl chr13:103,294,528...103,362,333
|
|
G
|
Lrp6
|
LDL receptor related protein 6
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of LRP6 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:168,997,937...169,131,716
Ensembl chr 4:167,270,353...167,400,497
|
|
G
|
Lrpprc
|
leucine-rich pentatricopeptide repeat containing
|
increases expression
|
ISO
|
Thimerosal results in increased expression of LRPPRC mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:9,859,816...9,942,294
Ensembl chr 6:9,859,867...9,942,293
|
|
G
|
Lrrc26
|
leucine rich repeat containing 26
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of LRRC26 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 3:8,102,361...8,103,687
Ensembl chr 3:8,102,361...8,103,687
|
|
G
|
Lrrc7
|
leucine rich repeat containing 7
|
increases expression
|
ISO
|
Thimerosal results in increased expression of LRRC7 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:247,146,616...247,634,945
Ensembl chr 2:247,147,752...247,634,547
|
|
G
|
Lrrc75b
|
leucine rich repeat containing 75B
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of LRRC75B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr20:13,099,741...13,105,942
Ensembl chr20:13,100,302...13,106,503
|
|
G
|
Lsm12
|
LSM12 homolog
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of LSM12 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:87,118,334...87,140,395
Ensembl chr10:87,118,416...87,140,396
|
|
G
|
Lsm14b
|
LSM family member 14B
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of LSM14B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:167,125,633...167,136,417
Ensembl chr 3:167,125,628...167,136,432
|
|
G
|
Lsm5
|
LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
|
increases expression
|
ISO
|
Thimerosal results in increased expression of LSM5 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:85,951,073...85,954,289
Ensembl chr 6:104,652,477...104,654,165 Ensembl chr 4:104,652,477...104,654,165
|
|
G
|
Lss
|
lanosterol synthase
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of LSS mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr20:12,090,641...12,118,230
Ensembl chr20:12,092,774...12,118,762
|
|
G
|
Lta4h
|
leukotriene A4 hydrolase
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of LTA4H mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:29,856,846...29,888,642
Ensembl chr 7:27,969,789...28,001,600
|
|
G
|
Ltbp2
|
latent transforming growth factor beta binding protein 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of LTBP2 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 6:110,161,029...110,261,586
Ensembl chr 6:104,429,947...104,526,208
|
|
G
|
Ltn1
|
listerin E3 ubiquitin protein ligase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of LTN1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr11:40,090,169...40,147,159
Ensembl chr11:26,603,903...26,660,886
|
|
G
|
Luzp1
|
leucine zipper protein 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of LUZP1 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 5:148,706,094...148,781,616
Ensembl chr 5:148,706,138...148,781,609
|
|
G
|
Lysmd4
|
LysM domain containing 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of LYSMD4 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 1:120,839,180...120,845,148
Ensembl chr 1:120,839,282...120,845,135
|
|
G
|
Mafb
|
MAF bZIP transcription factor B
|
increases expression
|
ISO
|
Thimerosal results in increased expression of MAFB mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr 3:169,417,890...169,419,810
Ensembl chr 3:148,998,122...149,000,031
|
|
G
|
Maff
|
MAF bZIP transcription factor F
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MAFF mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:112,792,787...112,804,139
Ensembl chr 7:110,912,499...110,923,851
|
|
G
|
Magel2
|
MAGE family member L2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MAGEL2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:115,880,142...115,884,684
Ensembl chr 1:115,880,474...115,884,250
|
|
G
|
Magi2
|
membrane associated guanylate kinase, WW and PDZ domain containing 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MAGI2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:15,278,518...16,762,427
Ensembl chr 4:14,386,399...15,870,240
|
|
G
|
Mansc1
|
MANSC domain containing 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MANSC1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:167,438,817...167,459,047
Ensembl chr 4:167,439,071...167,479,606
|
|
G
|
Maoa
|
monoamine oxidase A
|
multiple interactions
|
ISO
|
[NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MAOA mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr X:8,615,239...8,681,372
Ensembl chr X:6,030,795...6,099,593
|
|
G
|
Map2k2
|
mitogen activated protein kinase kinase 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MAP2K2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:9,241,449...9,264,216
Ensembl chr 7:8,580,905...8,610,243
|
|
G
|
Map3k11
|
mitogen-activated protein kinase kinase kinase 11
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MAP3K11 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:212,404,685...212,417,986
Ensembl chr 1:202,975,353...202,988,652
|
|
G
|
Map3k3
|
mitogen activated protein kinase kinase kinase 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MAP3K3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:91,519,976...91,588,651
Ensembl chr10:91,020,174...91,088,848
|
|
G
|
Map3k6
|
mitogen-activated protein kinase kinase kinase 6
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MAP3K6 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:150,724,029...150,736,113
Ensembl chr 5:145,440,346...145,452,212
|
|
G
|
Map4
|
microtubule-associated protein 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MAP4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:109,925,233...110,064,370
Ensembl chr 8:109,925,575...110,064,362
|
|
G
|
Map4k1
|
mitogen activated protein kinase kinase kinase kinase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MAP4K1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:93,398,460...93,419,996
Ensembl chr 1:84,271,069...84,292,493
|
|
G
|
Map4k5
|
mitogen-activated protein kinase kinase kinase kinase 5
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MAP4K5 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:88,284,087...88,377,118
Ensembl chr 6:88,284,094...88,376,799
|
|
G
|
Map9
|
microtubule-associated protein 9
|
increases expression
|
ISO
|
Thimerosal results in increased expression of MAP9 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:167,708,661...167,743,927
Ensembl chr 2:167,708,765...167,740,736
|
|
G
|
Mapk1
|
mitogen activated protein kinase 1
|
multiple interactions decreases phosphorylation
|
ISO
|
Acetylcysteine inhibits the reaction [Thimerosal results in decreased phosphorylation of MAPK1 protein]; SB 203580 inhibits the reaction [Thimerosal results in decreased phosphorylation of MAPK1 protein]
|
CTD |
PMID:18495191 |
|
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616
|
|
G
|
Mapk14
|
mitogen activated protein kinase 14
|
increases phosphorylation decreases expression
|
ISO
|
Thimerosal results in increased phosphorylation of MAPK14 protein Thimerosal results in decreased expression of MAPK14 mRNA
|
CTD |
PMID:15737199 PMID:27188386 |
|
NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,749,670...6,810,589
|
|
G
|
Mapk3
|
mitogen activated protein kinase 3
|
decreases phosphorylation multiple interactions increases phosphorylation
|
ISO
|
Thimerosal results in decreased phosphorylation of MAPK3 protein Acetylcysteine inhibits the reaction [Thimerosal results in decreased phosphorylation of MAPK3 protein]; SB 203580 inhibits the reaction [Thimerosal results in decreased phosphorylation of MAPK3 protein] Thimerosal results in increased phosphorylation of MAPK3 protein
|
CTD |
PMID:17698513 PMID:18495191 |
|
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863
|
|
G
|
Mapk8
|
mitogen-activated protein kinase 8
|
increases phosphorylation increases expression
|
ISO
|
Thimerosal results in increased phosphorylation of MAPK8 protein Thimerosal results in increased expression of MAPK8 mRNA
|
CTD |
PMID:18495191 PMID:27188386 |
|
NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,638,924...8,721,981
|
|
G
|
Mapk9
|
mitogen-activated protein kinase 9
|
increases phosphorylation
|
ISO
|
Thimerosal results in increased phosphorylation of MAPK9 protein
|
CTD |
PMID:17698513 |
|
NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,169,675...34,210,178
|
|
G
|
Mapkapk2
|
MAPK activated protein kinase 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MAPKAPK2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr13:45,066,027...45,112,326
Ensembl chr13:42,513,762...42,560,457
|
|
G
|
Marchf1
|
membrane associated ring-CH-type finger 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of MARCHF1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr16:23,255,551...24,114,290
Ensembl chr16:23,258,799...24,114,277
|
|
G
|
Mark4
|
microtubule affinity regulating kinase 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MARK4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:79,075,353...79,108,882
Ensembl chr 1:79,068,904...79,108,556
|
|
G
|
Mbd2
|
methyl-CpG binding domain protein 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MBD2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr18:66,449,196...66,516,112
Ensembl chr18:64,174,002...64,240,794
|
|
G
|
Mbnl2
|
muscleblind-like splicing regulator 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MBNL2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr15:97,385,278...97,542,924
Ensembl chr15:97,385,244...97,542,937
|
|
G
|
Mboat7
|
membrane bound O-acyltransferase domain containing 7
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MBOAT7 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:74,440,618...74,454,896
Ensembl chr 1:65,525,213...65,539,538
|
|
G
|
Mcph1
|
microcephalin 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of MCPH1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr16:71,021,855...71,224,067
Ensembl chr16:71,024,588...71,224,122
|
|
G
|
Mdh2
|
malate dehydrogenase 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MDH2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr12:26,530,886...26,543,841
Ensembl chr12:20,894,262...20,907,271
|
|
G
|
Meak7
|
MTOR associated protein, eak-7 homolog
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MEAK7 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr19:47,813,899...47,836,830
Ensembl chr19:47,811,416...47,841,278
|
|
G
|
Mecom
|
MDS1 and EVI1 complex locus
|
increases expression
|
ISO
|
Thimerosal results in increased expression of MECOM mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:114,837,815...115,393,052
Ensembl chr 2:112,909,321...113,464,590
|
|
G
|
Med13
|
mediator complex subunit 13
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MED13 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:71,086,978...71,176,535
Ensembl chr10:71,090,516...71,177,242
|
|
G
|
Med13l
|
mediator complex subunit 13L
|
increases expression
|
ISO
|
Thimerosal results in increased expression of MED13L mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr12:37,807,596...38,004,886
Ensembl chr12:37,808,285...38,004,473
|
|
G
|
Med16
|
mediator complex subunit 16
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MED16 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:9,798,641...9,811,172
Ensembl chr 7:9,798,668...9,811,172
|
|
G
|
Med17
|
mediator complex subunit 17
|
increases expression
|
ISO
|
Thimerosal results in increased expression of MED17 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:12,101,594...12,120,592
Ensembl chr 8:12,101,594...12,120,592
|
|
G
|
Med18
|
mediator complex subunit 18
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MED18 mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr 5:144,663,316...144,668,652
Ensembl chr 5:144,663,252...144,668,635
|
|
G
|
Med21
|
mediator complex subunit 21
|
increases expression
|
ISO
|
Thimerosal results in increased expression of MED21 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:179,560,509...179,583,811
Ensembl chr 4:179,560,579...179,567,548
|
|
G
|
Med25
|
mediator complex subunit 25
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MED25 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:95,359,961...95,375,827
Ensembl chr 1:95,360,284...95,375,877
|
|
G
|
Medag
|
mesenteric estrogen-dependent adipogenesis
|
multiple interactions
|
ISO
|
[NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MEDAG mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr12:5,613,191...5,634,583
Ensembl chr12:5,613,208...5,634,767
|
|
G
|
Megf6
|
multiple EGF-like-domains 6
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MEGF6 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 5:164,738,272...164,839,142
Ensembl chr 5:164,738,352...164,839,139
|
|
G
|
Mettl18
|
methyltransferase 18, RPL3 N3(tau)-histidine
|
increases expression
|
ISO
|
Thimerosal results in increased expression of METTL18 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr13:76,345,888...76,348,798
Ensembl chr13:76,345,957...76,348,836
|
|
G
|
Mgmt
|
O-6-methylguanine-DNA methyltransferase
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MGMT mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
|
|
G
|
Mia3
|
MIA SH3 domain ER export factor 3
|
increases expression
|
ISO
|
Thimerosal results in increased expression of MIA3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr13:94,970,421...95,012,071
Ensembl chr13:94,970,424...95,011,972
|
|
G
|
Mid1
|
midline 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MID1 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr X:27,678,248...28,053,049
Ensembl chr X:24,120,293...24,248,353
|
|
G
|
Mier3
|
MIER family member 3
|
increases expression
|
ISO
|
Thimerosal results in increased expression of MIER3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:43,287,546...43,316,422
Ensembl chr 2:43,287,916...43,316,136
|
|
G
|
Mill1
|
MHC I like leukocyte 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MICA mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:78,372,798...78,398,932
Ensembl chr 1:78,372,802...78,398,930
|
|
G
|
Mis18bp1
|
MIS18 binding protein 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MIS18BP1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:83,182,497...83,231,978
Ensembl chr 6:83,182,499...83,231,383
|
|
G
|
Mkln1
|
muskelin 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of MKLN1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:59,815,912...60,124,047
Ensembl chr 4:60,002,464...60,123,993
|
|
G
|
Mkrn3
|
makorin, ring finger protein, 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MKRN3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:115,926,774...115,929,288
Ensembl chr 1:115,926,776...115,929,283
|
|
G
|
Mlf2
|
myeloid leukemia factor 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MLF2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:157,739,651...157,744,325
Ensembl chr 4:157,728,756...157,744,317
|
|
G
|
Mmp16
|
matrix metallopeptidase 16
|
affects expression
|
ISO
|
Thimerosal affects the expression of MMP16 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:36,109,265...36,353,252
Ensembl chr 5:31,312,280...31,548,388
|
|
G
|
Mob1a
|
MOB kinase activator 1A
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MOB1A mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:115,831,581...115,848,561
Ensembl chr 4:115,831,551...115,848,561 Ensembl chr 1:115,831,551...115,848,561
|
|
G
|
Mpi
|
mannose phosphate isomerase
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MPI mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:57,947,883...57,956,205
Ensembl chr 8:57,947,893...57,956,150
|
|
G
|
Mrap2
|
melanocortin 2 receptor accessory protein 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MRAP2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:96,968,239...97,024,581
Ensembl chr 8:88,088,272...88,143,886
|
|
G
|
Mroh1
|
maestro heat-like repeat family member 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MROH1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:108,098,708...108,172,146
Ensembl chr 7:108,102,734...108,172,146
|
|
G
|
Mrpl1
|
mitochondrial ribosomal protein L1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of MRPL1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr14:13,300,522...13,359,654
Ensembl chr14:13,300,522...13,359,721
|
|
G
|
Mrpl10
|
mitochondrial ribosomal protein L10
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MRPL10 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:82,026,031...82,034,451
Ensembl chr10:82,026,031...82,034,443
|
|
G
|
Mrpl50
|
mitochondrial ribosomal protein L50
|
increases expression
|
ISO
|
Thimerosal results in increased expression of MRPL50 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:63,867,437...63,872,591
|
|
G
|
Mrps2
|
mitochondrial ribosomal protein S2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MRPS2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:11,803,044...11,806,341
Ensembl chr 3:11,801,310...11,806,313
|
|
G
|
Ms4a15
|
membrane spanning 4-domains A15
|
increases expression
|
ISO
|
Thimerosal results in increased expression of MS4A15 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 1:207,628,305...207,641,799
Ensembl chr 1:207,628,305...207,641,799
|
|
G
|
Msn
|
moesin
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MSN mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr X:60,996,043...61,064,011
Ensembl chr X:60,995,951...61,065,628
|
|
G
|
Mt1
|
metallothionein 1
|
affects expression increases expression
|
ISO
|
Thimerosal affects the expression of MT1 mRNA Thimerosal results in increased expression of MT1 mRNA; Thimerosal results in increased expression of MT1 protein
|
CTD |
PMID:19357975 PMID:19386279 |
|
NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049 Ensembl chr X:10,826,032...10,827,049
|
|
G
|
Mt2
|
metallothionein 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of MT2 mRNA; Thimerosal results in increased expression of MT2 protein
|
CTD |
PMID:19357975 |
|
NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,832,002...10,832,784
|
|
G
|
Mt3
|
metallothionein 3
|
increases expression
|
ISO
|
Thimerosal results in increased expression of MT3 mRNA
|
CTD |
PMID:19357975 |
|
NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158
|
|
G
|
Mta1
|
metastasis associated 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MTA1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:132,178,608...132,217,641
Ensembl chr 6:132,178,853...132,217,641
|
|
G
|
Mta2
|
metastasis associated 1 family, member 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MTA2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:205,838,181...205,846,903
Ensembl chr 1:205,837,964...205,846,946
|
|
G
|
Mtarc2
|
mitochondrial amidoxime reducing component 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MTARC2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr13:96,362,810...96,397,284
|
|
G
|
Mtcl2
|
microtubule crosslinking factor 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of MTCL2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:145,669,102...145,741,578
Ensembl chr 3:145,675,443...145,740,871
|
|
G
|
Mtcl3
|
MTCL family member 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MTCL3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:28,629,036...28,701,416
Ensembl chr 1:28,620,293...28,701,796
|
|
G
|
Mtfp1
|
mitochondrial fission process 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MTFP1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr14:78,968,434...78,972,274
Ensembl chr14:78,968,442...78,972,274
|
|
G
|
Mthfd2l
|
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
|
increases expression
|
ISO
|
Thimerosal results in increased expression of MTHFD2L mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr14:17,089,947...17,170,036
Ensembl chr14:17,089,952...17,170,112
|
|
G
|
Mtpap
|
mitochondrial poly(A) polymerase
|
increases expression
|
ISO
|
Thimerosal results in increased expression of MTPAP mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr17:53,320,739...53,341,500
Ensembl chr17:53,320,741...53,341,538
|
|
G
|
Mtr
|
5-methyltetrahydrofolate-homocysteine methyltransferase
|
multiple interactions decreases expression
|
ISO
|
Glutathione inhibits the reaction [Thimerosal inhibits the reaction [[Hydroxocobalamin co-treated with S-Adenosylmethionine] results in increased activity of MTR protein alternative form]]; Thimerosal affects the reaction [IGF1 protein results in increased activity of MTR protein]; Thimerosal inhibits the reaction [[Hydroxocobalamin co-treated with S-Adenosylmethionine] results in increased activity of MTR protein alternative form]; Thimerosal inhibits the reaction [mecobalamin results in increased activity of MTR protein alternative form] Thimerosal results in decreased expression of MTR mRNA
|
CTD |
PMID:14745455 PMID:26989453 PMID:27188386 |
|
NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822
|
|
G
|
Mvb12a
|
multivesicular body subunit 12A
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MVB12A mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr16:18,252,227...18,257,111
Ensembl chr16:18,252,222...18,257,539
|
|
G
|
Mxd1
|
max dimerization protein 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of MXD1 mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr 4:119,097,353...119,118,080
Ensembl chr 4:119,097,353...119,117,751
|
|
G
|
Mxra8
|
matrix remodeling associated 8
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MXRA8 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:166,448,919...166,453,645
Ensembl chr 5:166,449,154...166,453,636
|
|
G
|
Mynn
|
myoneurin
|
increases expression
|
ISO
|
Thimerosal results in increased expression of MYNN mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:112,779,654...112,797,188
Ensembl chr 2:112,779,657...112,796,397
|
|
G
|
Myo1e
|
myosin IE
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MYO1E mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:70,887,934...71,080,180
Ensembl chr 8:70,887,870...71,080,169
|
|
G
|
Myo5a
|
myosin VA
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MYO5A mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:75,811,985...75,980,049
Ensembl chr 8:75,812,412...75,975,918
|
|
G
|
Myo6
|
myosin VI
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MYO6 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:81,087,157...81,242,022
Ensembl chr 8:81,087,139...81,239,292
|
|
G
|
Myo9a
|
myosin IXA
|
increases expression
|
ISO
|
Thimerosal results in increased expression of MYO9A mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:60,149,234...60,352,330
Ensembl chr 8:60,149,234...60,350,514
|
|
G
|
Mzf1
|
myeloid zinc finger 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of MZF1 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 1:73,670,522...73,682,885
Ensembl chr 1:73,670,541...73,681,635
|
|
G
|
N4bp2l2
|
NEDD4 binding protein 2-like 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of N4BP2L2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr12:137,342...200,292
Ensembl chr12:103,590...197,784
|
|
G
|
N4bp3
|
Nedd4 binding protein 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of N4BP3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:35,898,031...35,906,704
Ensembl chr10:35,899,096...35,907,001
|
|
G
|
Naa16
|
N(alpha)-acetyltransferase 16, NatA auxiliary subunit
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of NAA16 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr15:61,120,704...61,179,979
Ensembl chr15:54,711,621...54,770,896
|
|
G
|
Naaa
|
N-acylethanolamine acid amidase
|
increases expression
|
ISO
|
Thimerosal results in increased expression of NAAA mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr14:15,777,306...15,796,411
Ensembl chr14:15,777,306...15,796,410
|
|
G
|
Naprt
|
nicotinate phosphoribosyltransferase
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of NAPRT mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:107,576,645...107,580,102
Ensembl chr 7:107,576,627...107,580,102
|
|
G
|
Nasp
|
nuclear autoantigenic sperm protein
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of NASP mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:130,057,363...130,083,003
Ensembl chr 5:130,057,363...130,082,928
|
|
G
|
Natd1
|
N-acetyltransferase domain containing 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of NATD1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:46,079,650...46,089,829
|
|
G
|
Nav3
|
neuron navigator 3
|
increases expression
|
ISO
|
Thimerosal results in increased expression of NAV3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:46,938,577...47,726,839
Ensembl chr 7:45,054,296...45,840,698
|
|
G
|
Nbas
|
NBAS subunit of NRZ tethering complex
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of NBAS mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:36,048,357...36,353,206
Ensembl chr 6:36,048,191...36,352,984
|
|
G
|
Ncam1
|
neural cell adhesion molecule 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of NCAM1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:49,865,629...50,165,687
Ensembl chr 8:49,865,633...50,166,014
|
|
G
|
Ndrg1
|
N-myc downstream regulated 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of NDRG1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:100,573,526...100,614,902
Ensembl chr 7:98,684,487...98,725,880
|
|
G
|
Ndufa5
|
NADH:ubiquinone oxidoreductase subunit A5
|
increases expression
|
ISO
|
Thimerosal results in increased expression of NDUFA5 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:53,962,877...53,971,235
Ensembl chr 4:52,995,546...53,005,598 Ensembl chr 5:52,995,546...53,005,598
|
|
G
|
Ndufa9
|
NADH:ubiquinone oxidoreductase subunit A9
|
increases expression
|
ISO
|
Thimerosal results in increased expression of NDUFA9 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:161,345,398...161,374,188
Ensembl chr 4:159,659,242...159,688,018
|
|
G
|
Ndufaf4
|
NADH:ubiquinone oxidoreductase complex assembly factor 4
|
increases expression
|
ISO
|
Thimerosal results in increased expression of NDUFAF4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:38,605,169...38,610,341
Ensembl chr 5:38,605,153...38,610,336
|
|
G
|
Ndufb7
|
NADH:ubiquinone oxidoreductase subunit B7
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of NDUFB7 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr19:41,472,953...41,477,291
Ensembl chr19:24,568,241...24,572,579
|
|
G
|
Nefh
|
neurofilament heavy chain
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of NEFH mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
|
|
G
|
Negr1
|
neuronal growth regulator 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of NEGR1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:245,624,460...246,359,605
Ensembl chr 2:245,624,435...246,356,730
|
|
G
|
Nes
|
nestin
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of NES mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:175,735,715...175,745,631
Ensembl chr 2:173,438,734...173,447,777
|
|
G
|
Nf1
|
neurofibromin 1
|
affects expression
|
ISO
|
Thimerosal affects the expression of NF1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:64,803,986...65,037,086
Ensembl chr10:64,306,301...64,536,658
|
|
G
|
Nfat5
|
nuclear factor of activated T-cells 5
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of NFAT5 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr19:52,108,982...52,196,418
Ensembl chr19:35,199,016...35,286,675
|
|
G
|
Nfatc2ip
|
nuclear factor of activated T-cells 2 interacting protein
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of NFATC2IP mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:190,385,416...190,403,309
Ensembl chr 1:180,955,043...180,971,747
|
|
G
|
Nfe2l2
|
NFE2 like bZIP transcription factor 2
|
increases expression multiple interactions
|
ISO
|
Thimerosal results in increased expression of NFE2L2 protein Aluminum Hydroxide promotes the reaction [Thimerosal results in increased expression of NFE2L2 protein]
|
CTD |
PMID:36411272 |
|
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737
|
|
G
|
Nfyb
|
nuclear transcription factor Y subunit beta
|
increases expression
|
ISO
|
Thimerosal results in increased expression of NFYB mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:22,852,543...22,868,116
Ensembl chr 7:20,964,993...20,980,565
|
|
G
|
Ngf
|
nerve growth factor
|
multiple interactions decreases response to substance
|
ISO
|
[Thimerosal co-treated with NGF protein] results in decreased phosphorylation of NTRK1 protein NGF protein results in decreased susceptibility to Thimerosal
|
CTD |
PMID:15843506 |
|
NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:189,901,058...189,954,452
|
|
G
|
Nipal3
|
NIPA-like domain containing 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of NIPAL3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:147,687,310...147,725,838
Ensembl chr 5:147,685,288...147,726,351
|
|
G
|
Nipbl
|
NIPBL, cohesin loading factor
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of NIPBL mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:57,399,443...57,586,770
Ensembl chr 2:57,399,445...57,565,899
|
|
G
|
Nipsnap1
|
nipsnap homolog 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of NIPSNAP1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr14:79,734,234...79,758,101
Ensembl chr14:79,734,209...79,758,098
|
|
G
|
Nkain2
|
sodium/potassium transporting ATPase interacting 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of NKAIN2 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 1:24,668,627...25,877,051
Ensembl chr 1:24,669,462...25,877,064
|
|
G
|
Nlrx1
|
NLR family member X1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of NLRX1 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 8:44,588,476...44,606,678
Ensembl chr 8:44,590,048...44,606,484
|
|
G
|
Nme4
|
NME/NM23 nucleoside diphosphate kinase 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of NME4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:15,114,624...15,118,479
Ensembl chr10:15,002,926...15,118,479
|
|
G
|
Nog
|
noggin
|
multiple interactions decreases expression
|
ISO
|
[NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of APOH mRNA; [NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CPEB2 mRNA; [NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of LNPEP mRNA; [NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MAP1LC3C mRNA; [NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MEDAG mRNA; [NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PITPNM2 mRNA; [NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SEPSECS mRNA; [NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SLCO4A1-AS1 mRNA; [NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SNCAIP mRNA; [NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TMC5 mRNA; [NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABTB3 mRNA; [NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CALML4 mRNA; [NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CAPN5 mRNA; [NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FLCN mRNA; [NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FRA10AC1 mRNA; [NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MAOA mRNA; [NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of OTULINL mRNA; [NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PIAS2 mRNA; [NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PLEKHF2 mRNA; [NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of POP1 mRNA; [NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SAPCD2 mRNA; [NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC25A21 mRNA; [NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC30A5 mRNA; [NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TTC39C mRNA Thimerosal results in decreased expression of NOG mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:74,625,874...74,627,501
Ensembl chr10:74,128,712...74,130,339
|
|
G
|
Nol3
|
nucleolar protein 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of NOL3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
|
|
G
|
Nop53
|
NOP53 ribosome biogenesis factor
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of NOP53 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:85,757,271...85,765,089
Ensembl chr 1:76,629,069...76,636,902
|
|
G
|
Npas3
|
neuronal PAS domain protein 3
|
increases expression
|
ISO
|
Thimerosal results in increased expression of NPAS3 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 6:70,702,773...71,527,928
Ensembl chr 6:70,703,170...71,524,884
|
|
G
|
Npat
|
nuclear protein, co-activator of histone transcription
|
increases expression
|
ISO
|
Thimerosal results in increased expression of NPAT mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr 8:53,932,993...53,970,875
Ensembl chr 8:53,932,993...53,970,875
|
|
G
|
Nphp1
|
nephrocystin 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of NPHP1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:135,413,927...135,469,505
Ensembl chr 3:114,960,650...115,016,234
|
|
G
|
Nprl3
|
NPR3-like, GATOR1 complex subunit
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of NPRL3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:15,355,361...15,395,812
Ensembl chr10:15,355,355...15,395,810
|
|
G
|
Nqo1
|
NAD(P)H quinone dehydrogenase 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of NQO1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557
|
|
G
|
Nr2c2
|
nuclear receptor subfamily 2, group C, member 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of NR2C2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:124,610,216...124,666,813
Ensembl chr 4:124,608,960...124,661,902
|
|
G
|
Nr4a1
|
nuclear receptor subfamily 4, group A, member 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of NR4A1 mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr 7:134,247,153...134,268,044
Ensembl chr 7:132,374,840...132,389,297
|
|
G
|
Nr4a2
|
nuclear receptor subfamily 4, group A, member 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of NR4A2 mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr 3:62,098,739...62,115,926
Ensembl chr 3:41,689,851...41,697,877
|
|
G
|
Nrdc
|
nardilysin convertase
|
increases expression
|
ISO
|
Thimerosal results in increased expression of NRDC mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:128,983,395...129,047,578
Ensembl chr 5:123,755,806...123,818,595
|
|
G
|
Nrm
|
nurim
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of NRM mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr20:2,888,321...2,892,804
Ensembl chr20:2,877,567...2,891,802
|
|
G
|
Nt5dc2
|
5'-nucleotidase domain containing 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of NT5DC2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr16:6,322,485...6,330,538
Ensembl chr16:6,322,236...6,330,537
|
|
G
|
Ntrk1
|
neurotrophic receptor tyrosine kinase 1
|
multiple interactions
|
ISO
|
[Thimerosal co-treated with NGF protein] results in decreased phosphorylation of NTRK1 protein
|
CTD |
PMID:15843506 |
|
NCBI chr 2:175,534,844...175,551,664
Ensembl chr 2:173,236,963...173,253,770
|
|
G
|
Ntrk3
|
neurotrophic receptor tyrosine kinase 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of NTRK3 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 1:141,526,192...141,913,575
Ensembl chr 1:132,132,849...132,503,286
|
|
G
|
Nub1
|
negative regulator of ubiquitin-like proteins 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of NUB1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:11,335,376...11,366,263
Ensembl chr 4:10,442,917...10,473,694
|
|
G
|
Nynrin
|
NYN domain and retroviral integrase containing
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of NYNRIN mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr15:29,332,873...29,355,215
Ensembl chr15:29,332,869...29,355,215
|
|
G
|
Obi1
|
ORC ubiquitin ligase 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of OBI1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr15:81,269,413...81,308,734
Ensembl chr15:81,269,416...81,308,734
|
|
G
|
Obsl1
|
obscurin like cytoskeletal adaptor 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of OBSL1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:76,967,802...76,993,771
Ensembl chr 9:76,974,253...76,993,560
|
|
G
|
Ociad1
|
OCIA domain containing 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of OCIAD1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr14:34,897,851...34,915,291
Ensembl chr14:34,897,847...34,915,286
|
|
G
|
Omp
|
olfactory marker protein
|
increases expression
|
ISO
|
Thimerosal results in increased expression of OMP mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 1:152,440,278...152,440,828
Ensembl chr 1:152,433,652...152,441,922
|
|
G
|
Osbpl8
|
oxysterol binding protein-like 8
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of OSBPL8 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:46,596,944...46,749,888
Ensembl chr 7:46,596,983...46,749,888
|
|
G
|
Otub2
|
OTU deubiquitinase, ubiquitin aldehyde binding 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of OTUB2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:122,545,067...122,563,657
Ensembl chr 6:122,545,061...122,563,644
|
|
G
|
Otud4
|
OTU deubiquitinase 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of OTUD4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr19:28,236,713...28,279,815
Ensembl chr19:28,236,713...28,279,815
|
|
G
|
Otud6b
|
OTU deubiquitinase 6B
|
increases expression
|
ISO
|
Thimerosal results in increased expression of OTUD6B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:28,181,992...28,214,486
Ensembl chr 5:28,023,594...28,214,334
|
|
G
|
Otulinl
|
OTU deubiquitinase with linear linkage specificity like
|
multiple interactions
|
ISO
|
[NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of OTULINL mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:80,136,411...80,164,290
Ensembl chr 2:78,408,593...78,433,838
|
|
G
|
P4ha1
|
prolyl 4-hydroxylase subunit alpha 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of P4HA1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr20:27,784,696...27,895,785
Ensembl chr20:27,302,141...27,352,786
|
|
G
|
Pacsin1
|
protein kinase C and casein kinase substrate in neurons 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PACSIN1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr20:5,718,134...5,768,064
Ensembl chr20:5,719,857...5,765,313
|
|
G
|
Paip2b
|
poly(A) binding protein interacting protein 2B
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PAIP2B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:117,849,625...117,881,021
Ensembl chr 4:116,292,020...116,323,379
|
|
G
|
Pald1
|
phosphatase domain containing, paladin 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PALD1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr20:29,269,814...29,334,850
Ensembl chr20:29,270,193...29,334,858
|
|
G
|
Pank2
|
pantothenate kinase 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of PANK2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:138,936,448...138,974,196
Ensembl chr 3:118,483,444...118,518,320
|
|
G
|
Pard3b
|
par-3 family cell polarity regulator beta
|
increases expression
|
ISO
|
Thimerosal results in increased expression of PARD3B mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 9:70,532,358...71,561,044
Ensembl chr 9:63,038,436...64,068,053
|
|
G
|
Parpbp
|
PARP1 binding protein
|
increases expression
|
ISO
|
Thimerosal results in increased expression of PARPBP mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:22,511,427...22,580,834
Ensembl chr 7:22,511,427...22,573,695
|
|
G
|
Pc
|
pyruvate carboxylase
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PC mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:211,228,708...211,327,792
Ensembl chr 1:201,804,267...201,898,380
|
|
G
|
Pcbp2
|
poly(rC) binding protein 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PCBP2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:133,605,375...133,631,312
Ensembl chr 7:133,605,573...133,629,863
|
|
G
|
Pcdha9
|
protocadherin alpha 9
|
increases expression
|
ISO
|
Thimerosal results in increased expression of PCDHA9 mRNA
|
CTD |
PMID:27188386 |
|
Ensembl chr18:28,581,225...28,846,211
|
|
G
|
Pclo
|
piccolo (presynaptic cytomatrix protein)
|
increases expression
|
ISO
|
Thimerosal results in increased expression of PCLO mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:19,691,439...20,050,015
Ensembl chr 4:19,695,315...20,049,885
|
|
G
|
Pcm1
|
pericentriolar material 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PCM1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr16:51,008,315...51,105,261
Ensembl chr16:51,008,315...51,105,091
|
|
G
|
Pcnp
|
PEST proteolytic signal containing nuclear protein
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PCNP mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr11:44,592,766...44,607,372
Ensembl chr11:44,592,742...44,607,348
|
|
G
|
Pcnx1
|
pecanex 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of PCNX1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:101,565,461...101,702,339
Ensembl chr 6:101,565,580...101,702,271
|
|
G
|
Pcp4
|
Purkinje cell protein 4
|
increases expression
|
ISO
|
Thimerosal results in increased expression of PCP4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr11:35,759,711...35,861,725
Ensembl chr11:35,800,713...35,861,725
|
|
G
|
Pcsk2
|
proprotein convertase subtilisin/kexin type 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of PCSK2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:130,880,422...131,183,127
Ensembl chr 3:130,880,422...131,183,127
|
|
G
|
Pdia3
|
protein disulfide isomerase family A, member 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PDIA3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:128,841,781...128,865,733
Ensembl chr 3:108,388,245...108,413,236
|
|
G
|
Pdk1
|
pyruvate dehydrogenase kinase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PDK1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:77,113,464...77,144,145
Ensembl chr 3:56,705,871...56,733,038
|
|
G
|
Pdlim4
|
PDZ and LIM domain 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PDLIM4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:38,699,444...38,713,696
Ensembl chr10:38,198,689...38,212,938
|
|
G
|
Pdss2
|
decaprenyl diphosphate synthase subunit 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PDSS2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr20:46,709,631...46,938,704
Ensembl chr20:46,709,649...46,938,708
|
|
G
|
Pdyn
|
prodynorphin
|
multiple interactions
|
ISO
|
[SOD1 protein mutant form results in increased susceptibility to Thimerosal] which results in increased expression of PDYN mRNA; Resveratrol inhibits the reaction [[SOD1 protein mutant form results in increased susceptibility to Thimerosal] which results in increased expression of PDYN mRNA]
|
CTD |
PMID:30503815 |
|
NCBI chr 3:137,354,161...137,366,503
Ensembl chr 3:116,900,992...116,913,334
|
|
G
|
Peds1
|
plasmanylethanolamine desaturase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PEDS1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:156,350,135...156,369,309
Ensembl chr 3:156,349,526...156,369,314
|
|
G
|
Pelp1
|
proline, glutamate and leucine rich protein 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PELP1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:55,094,798...55,111,833
Ensembl chr10:55,094,796...55,111,994
|
|
G
|
Pex6
|
peroxisomal biogenesis factor 6
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PEX6 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:14,258,145...14,270,335
Ensembl chr 9:14,258,145...14,270,303
|
|
G
|
Pfdn4
|
prefoldin subunit 4
|
increases expression
|
ISO
|
Thimerosal results in increased expression of PFDN4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:159,303,173...159,311,221
Ensembl chr 3:159,303,071...159,311,219
|
|
G
|
Pfkfb2
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PFKFB2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr13:42,147,473...42,174,699
Ensembl chr13:42,147,478...42,174,699
|
|
G
|
Pfkfb4
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PFKFB4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:109,643,558...109,687,006
Ensembl chr 8:109,643,937...109,685,634
|
|
G
|
Pfkp
|
phosphofructokinase, platelet
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PFKP mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr17:63,729,743...63,794,026
Ensembl chr17:63,729,780...63,794,018
|
|
G
|
Pfn1
|
profilin 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PFN1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:55,365,263...55,367,968
Ensembl chr10:55,365,262...55,527,631
|
|
G
|
Pgam1
|
phosphoglycerate mutase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PGAM1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452
|
|
G
|
Pgap1
|
post-GPI attachment to proteins inositol deacylase 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of PGAP1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:55,975,574...56,044,325
Ensembl chr 9:55,975,667...56,044,464
|
|
G
|
Pgap2
|
post-GPI attachment to proteins 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PGAP2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:156,591,540...156,618,116
Ensembl chr 1:156,591,615...156,618,114
|
|
G
|
Pgap4
|
post-GPI attachment to proteins GalNAc transferase 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PGAP4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:63,931,916...63,947,004
Ensembl chr 5:63,930,682...63,951,716
|
|
G
|
Pgap6
|
post-GPI attachment to proteins 6
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PGAP6 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:15,138,918...15,148,431
Ensembl chr10:15,138,959...15,148,431
|
|
G
|
Pgf
|
placental growth factor
|
increases expression
|
ISO
|
Thimerosal results in increased expression of PGF mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr 6:110,547,165...110,557,747
Ensembl chr 6:104,816,104...104,826,685
|
|
G
|
Pgk1
|
phosphoglycerate kinase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PGK1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr X:75,336,988...75,352,962
Ensembl chr X:71,271,440...71,287,418
|
|
G
|
Pgls
|
6-phosphogluconolactonase
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PGLS mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr16:18,300,317...18,305,803
Ensembl chr16:18,300,317...18,305,803
|
|
G
|
Pgm1
|
phosphoglucomutase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PGM1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:114,595,298...114,654,728
Ensembl chr 5:114,595,293...114,654,728
|
|
G
|
Pgpep1
|
pyroglutamyl-peptidase I
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PGPEP1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr16:18,770,563...18,782,968
Ensembl chr16:18,771,021...18,783,478
|
|
G
|
Phax
|
phosphorylated adaptor for RNA export
|
increases expression
|
ISO
|
Thimerosal results in increased expression of PHAX mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr18:50,053,133...50,069,823
Ensembl chr18:50,053,023...50,069,823
|
|
G
|
Phf20
|
PHD finger protein 20
|
increases expression
|
ISO
|
Thimerosal results in increased expression of PHF20 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:144,710,253...144,816,696
Ensembl chr 3:144,710,353...144,814,439
|
|
G
|
Phf20l1
|
PHD finger protein 20-like 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PHF20L1 mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr 7:98,330,580...98,396,526
Ensembl chr 7:98,330,580...98,396,526
|
|
G
|
Phf21a
|
PHD finger protein 21A
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PHF21A mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:78,158,760...78,331,903
Ensembl chr 3:78,194,549...78,331,865
|
|
G
|
Phkb
|
phosphorylase kinase regulatory subunit beta
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PHKB mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr19:37,179,937...37,383,979
Ensembl chr19:21,025,733...21,210,633
|
|
G
|
Phldb2
|
pleckstrin homology-like domain, family B, member 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PHLDB2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr11:54,859,173...55,078,212
Ensembl chr11:54,859,135...55,078,467
|
|
G
|
Phldb3
|
pleckstrin homology-like domain, family B, member 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PHLDB3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:89,328,991...89,347,446
Ensembl chr 1:80,201,578...80,219,534
|
|
G
|
Phtf2
|
putative homeodomain transcription factor 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of PHTF2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:14,215,190...14,330,549
Ensembl chr 4:14,215,263...14,330,513
|
|
G
|
Pi4k2a
|
phosphatidylinositol 4-kinase type 2 alpha
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PI4K2A mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:240,902,804...240,929,234
Ensembl chr 1:240,902,855...240,929,337
|
|
G
|
Pias2
|
protein inhibitor of activated STAT, 2
|
multiple interactions
|
ISO
|
[NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PIAS2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr18:72,883,008...72,989,486
Ensembl chr18:70,607,665...70,710,033
|
|
G
|
Pik3c2a
|
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
|
increases expression
|
ISO
|
Thimerosal results in increased expression of PIK3C2A mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:170,577,942...170,684,353
Ensembl chr 1:170,577,942...170,683,472
|
|
G
|
Pik3ca
|
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
|
increases expression
|
ISO
|
Thimerosal results in increased expression of PIK3CA mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:117,103,643...117,177,411
Ensembl chr 2:115,174,984...115,249,032
|
|
G
|
Pin4
|
peptidylprolyl cis/trans isomerase, NIMA-interacting 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PIN4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr X:67,232,066...67,238,709
Ensembl chr X:67,232,081...67,238,702
|
|
G
|
Pir
|
pirin
|
increases expression
|
ISO
|
Thimerosal results in increased expression of PIR mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr X:33,740,428...33,851,049
Ensembl chr X:30,108,538...30,219,218
|
|
G
|
Pitpnm2
|
phosphatidylinositol transfer protein, membrane-associated 2
|
multiple interactions
|
ISO
|
[NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PITPNM2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr12:32,347,455...32,479,103
Ensembl chr12:32,380,805...32,479,102
|
|
G
|
Pkn3
|
protein kinase N3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PKN3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:33,747,610...33,761,405
Ensembl chr 3:13,335,041...13,363,567
|
|
G
|
Plaat1
|
phospholipase A and acyltransferase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PLAAT1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr11:71,517,492...71,537,142
Ensembl chr11:71,517,493...71,527,020
|
|
G
|
Plcb4
|
phospholipase C, beta 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PLCB4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:122,952,965...123,322,522
Ensembl chr 3:122,953,196...123,322,392
|
|
G
|
Plcg1
|
phospholipase C, gamma 1
|
increases cleavage
|
ISO
|
Thimerosal results in increased cleavage of PLCG1 protein
|
CTD |
PMID:16649253 |
|
NCBI chr 3:169,805,299...169,836,040
Ensembl chr 3:149,385,587...149,416,330
|
|
G
|
Plekha2
|
pleckstrin homology domain containing A2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PLEKHA2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr16:73,641,338...73,704,068
Ensembl chr16:66,939,109...66,999,395
|
|
G
|
Plekha5
|
pleckstrin homology domain containing A5
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PLEKHA5 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:173,333,891...173,503,546
Ensembl chr 4:173,334,055...173,503,546
|
|
G
|
Plekha6
|
pleckstrin homology domain containing A6
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PLEKHA6 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr13:44,614,740...44,754,951
Ensembl chr13:44,615,011...44,754,673
|
|
G
|
Plekhb1
|
pleckstrin homology domain containing B1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PLEKHB1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:154,998,798...155,013,094
Ensembl chr 1:154,998,800...155,016,142
|
|
G
|
Plekhf2
|
pleckstrin homology and FYVE domain containing 2
|
multiple interactions
|
ISO
|
[NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PLEKHF2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:24,091,077...24,106,758
Ensembl chr 5:24,090,688...24,106,601
|
|
G
|
Plekhg4
|
pleckstrin homology and RhoGEF domain containing G4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PLEKHG4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr19:50,161,722...50,176,491
Ensembl chr19:33,249,706...33,266,357
|
|
G
|
Plk2
|
polo-like kinase 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of PLK2 mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr 2:43,702,536...43,708,305
Ensembl chr 2:41,969,176...41,974,947
|
|
G
|
Plod1
|
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PLOD1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:163,623,847...163,650,737
Ensembl chr 5:158,340,490...158,367,620
|
|
G
|
Plppr3
|
phospholipid phosphatase related 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PLPPR3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:9,831,162...9,842,434
Ensembl chr 7:9,831,162...9,845,296
|
|
G
|
Plxnc1
|
plexin C1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PLXNC1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:29,390,038...29,543,985
Ensembl chr 7:29,390,048...29,543,779
|
|
G
|
Pmch
|
pro-melanin-concentrating hormone
|
increases expression
|
ISO
|
Thimerosal results in increased expression of PMCH mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:22,511,934...22,513,250
Ensembl chr 7:22,511,934...22,513,250
|
|
G
|
Pml
|
PML nuclear body scaffold
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PML mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
|
|
G
|
Pnpla3
|
patatin-like phospholipase domain containing 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PNPLA3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:115,293,538...115,314,077
Ensembl chr 7:115,293,538...115,314,077
|
|
G
|
Pole4
|
DNA polymerase epsilon 4, accessory subunit
|
increases expression
|
ISO
|
Thimerosal results in increased expression of POLE4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:115,165,285...115,171,097
Ensembl chr 4:115,165,285...115,171,097
|
|
G
|
Polrmt
|
RNA polymerase mitochondrial
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of POLRMT mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:9,959,532...9,969,791
Ensembl chr 7:9,959,576...9,969,791
|
|
G
|
Pomc
|
proopiomelanocortin
|
increases expression
|
ISO
|
Thimerosal results in increased expression of POMC mRNA; Thimerosal results in increased expression of POMC protein
|
CTD |
PMID:24675092 |
|
NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:26,939,837...26,945,664
|
|
G
|
Pomgnt2
|
protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of POMGNT2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:130,522,607...130,538,273
Ensembl chr 8:121,644,970...121,660,757
|
|
G
|
Pop1
|
POP1 homolog, ribonuclease P/MRP subunit
|
multiple interactions
|
ISO
|
[NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of POP1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:65,705,348...65,733,143
Ensembl chr 7:65,705,368...65,733,141
|
|
G
|
Pou1f1
|
POU class 1 homeobox 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of POU1F1 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr11:16,763,312...16,781,295
Ensembl chr11:3,317,058...3,334,801
|
|
G
|
Ppfia4
|
PTPRF interacting protein alpha 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PPFIA4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr13:45,753,827...45,802,305
Ensembl chr13:45,753,827...45,802,261
|
|
G
|
Ppfibp1
|
PPFIA binding protein 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PPFIBP1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:179,807,579...179,951,428
Ensembl chr 4:179,808,794...179,951,428
|
|
G
|
Ppia
|
peptidylprolyl isomerase A
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PPIA mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
|
|
G
|
Ppil2
|
peptidylprolyl isomerase like 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PPIL2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr11:83,897,719...83,920,970
Ensembl chr11:83,897,764...83,922,144
|
|
G
|
Ppp1r14a
|
protein phosphatase 1, regulatory (inhibitor) subunit 14A
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PPP1R14A mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:84,583,127...84,590,743
Ensembl chr 1:84,586,627...84,590,671
|
|
G
|
Ppp1r3b
|
protein phosphatase 1, regulatory subunit 3B
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PPP1R3B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr16:63,533,318...63,545,683
Ensembl chr16:56,829,660...56,842,406
|
|
G
|
Ppp1r3e
|
protein phosphatase 1, regulatory subunit 3E
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PPP1R3E mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr15:28,348,443...28,349,603
Ensembl chr15:28,347,854...28,349,603
|
|
G
|
Prdm2
|
PR/SET domain 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PRDM2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:155,421,066...155,531,884
Ensembl chr 5:155,422,134...155,531,825
|
|
G
|
Prelid2
|
PRELI domain containing 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PRELID2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr18:33,869,934...33,961,320
Ensembl chr18:33,873,599...33,961,225
|
|
G
|
Prepl
|
prolyl endopeptidase-like
|
increases expression
|
ISO
|
Thimerosal results in increased expression of PREPL mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:9,580,367...9,609,957
Ensembl chr 6:9,580,217...9,607,772
|
|
G
|
Prex2
|
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of PREX2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:7,937,692...8,253,112
Ensembl chr 5:7,942,573...8,253,068
|
|
G
|
Prim2
|
DNA primase subunit 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of PRIM2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:35,692,376...35,904,521
Ensembl chr 9:35,692,376...35,903,030
|
|
G
|
Prima1
|
proline rich membrane anchor 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PRIMA1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:128,094,686...128,155,592
Ensembl chr 6:122,338,370...122,389,921
|
|
G
|
Prkab2
|
protein kinase AMP-activated non-catalytic subunit beta 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PRKAB2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:187,946,008...187,961,615
Ensembl chr 2:185,257,213...185,269,872
|
|
G
|
Prkd2
|
protein kinase D2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PRKD2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:86,640,095...86,670,476
Ensembl chr 1:77,513,986...77,542,376
|
|
G
|
Prkd3
|
protein kinase D3
|
increases expression
|
ISO
|
Thimerosal results in increased expression of PRKD3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:16,032,507...16,108,444
Ensembl chr 6:16,032,585...16,108,443
|
|
G
|
Prkrip1
|
PRKR interacting protein 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PRKRIP1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr12:20,470,802...20,491,789
Ensembl chr12:20,470,820...20,489,115
|
|
G
|
Prl
|
prolactin
|
increases expression
|
ISO
|
Thimerosal results in increased expression of PRL mRNA; Thimerosal results in increased expression of PRL protein
|
CTD |
PMID:24675092 |
|
NCBI chr17:38,287,355...38,298,234
Ensembl chr17:37,860,007...37,870,062
|
|
G
|
Prlr
|
prolactin receptor
|
increases expression
|
ISO
|
Thimerosal results in increased expression of PRLR mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:60,861,391...61,051,883
Ensembl chr 2:59,134,588...59,324,718
|
|
G
|
Prpf6
|
pre-mRNA processing factor 6
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PRPF6 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:189,084,465...189,148,705
Ensembl chr 3:168,704,299...168,774,991
|
|
G
|
Prr14l
|
proline rich 14-like
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PRR14L mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr14:77,869,848...77,937,141
Ensembl chr14:77,869,799...77,936,521
|
|
G
|
Prr5l
|
proline rich 5 like
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PRR5L mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:88,001,951...88,173,532
Ensembl chr 3:88,003,617...88,082,763
|
|
G
|
Prrc2c
|
proline-rich coiled-coil 2C
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PRRC2C mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr13:75,003,995...75,073,701
Ensembl chr13:75,004,010...75,073,643
|
|
G
|
Prrt1
|
proline-rich transmembrane protein 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PRRT1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr20:4,117,957...4,121,643
Ensembl chr20:4,117,957...4,121,600
|
|
G
|
Psme4
|
proteasome activator subunit 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PSME4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr14:104,505,716...104,609,410
Ensembl chr14:104,505,716...104,609,408
|
|
G
|
Psmf1
|
proteasome inhibitor subunit 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PSMF1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:140,235,371...140,260,546
Ensembl chr 3:140,235,373...140,260,546
|
|
G
|
Ptbp2
|
polypyrimidine tract binding protein 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of PTBP2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:207,812,659...207,874,019
Ensembl chr 2:207,812,920...207,873,506
|
|
G
|
Ptchd4
|
patched domain containing 4
|
increases expression
|
ISO
|
Thimerosal results in increased expression of PTCHD4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:18,462,934...18,666,272
Ensembl chr 9:18,463,737...18,665,705
|
|
G
|
Ptk2
|
protein tyrosine kinase 2
|
multiple interactions increases response to substance
|
ISO
|
[[Thimerosal results in increased abundance of Reactive Oxygen Species] which results in increased activity of CASP3 protein] which results in increased cleavage of PTK2 protein; Acetylcysteine inhibits the reaction [[[Thimerosal results in increased abundance of Reactive Oxygen Species] which results in increased activity of CASP3 protein] which results in increased cleavage of PTK2 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[[Thimerosal results in increased abundance of Reactive Oxygen Species] which results in increased activity of CASP3 protein] which results in increased cleavage of PTK2 protein] PTK2 protein results in increased susceptibility to Thimerosal
|
CTD |
PMID:17888894 |
|
NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
|
|
G
|
Ptms
|
parathymosin
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PTMS mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:157,722,384...157,726,575
Ensembl chr 4:157,722,386...157,727,009
|
|
G
|
Ptov1
|
PTOV1, extended AT-hook containing adaptor protein
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PTOV1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:95,347,065...95,354,514
Ensembl chr 1:95,347,068...95,353,613
|
|
G
|
Ptp4a3
|
protein tyrosine phosphatase 4A3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PTP4A3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:105,650,640...105,660,921
Ensembl chr 7:105,628,029...105,660,919
|
|
G
|
Ptpn12
|
protein tyrosine phosphatase, non-receptor type 12
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PTPN12 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:14,020,997...14,092,931
Ensembl chr 4:14,021,052...14,092,927
|
|
G
|
Ptpn4
|
protein tyrosine phosphatase, non-receptor type 4
|
increases expression
|
ISO
|
Thimerosal results in increased expression of PTPN4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr13:30,772,012...30,952,340
Ensembl chr13:30,776,682...30,952,170
|
|
G
|
Ptpra
|
protein tyrosine phosphatase, receptor type, A
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PTPRA mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:138,103,261...138,212,835
Ensembl chr 3:117,650,183...117,759,728
|
|
G
|
Ptprk
|
protein tyrosine phosphatase, receptor type, K
|
increases expression
|
ISO
|
Thimerosal results in increased expression of PTPRK mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:18,557,091...19,056,297
Ensembl chr 1:16,850,576...17,103,605
|
|
G
|
Purb
|
purine rich element binding protein B
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PURB mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr14:81,342,374...81,344,857
Ensembl chr14:81,336,448...81,351,432
|
|
G
|
Pxmp4
|
peroxisomal membrane protein 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PXMP4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:143,093,371...143,110,620
Ensembl chr 3:143,093,018...143,110,651
|
|
G
|
Pygl
|
glycogen phosphorylase L
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of PYGL mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:94,433,558...94,476,219
Ensembl chr 6:88,697,593...88,740,310
|
|
G
|
Pyroxd1
|
pyridine nucleotide-disulphide oxidoreductase domain 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of PYROXD1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:175,292,124...175,311,143
Ensembl chr 4:175,292,177...175,308,689
|
|
G
|
Qprt
|
quinolinate phosphoribosyltransferase
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of QPRT mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:181,718,189...181,733,486
Ensembl chr 1:181,718,190...181,733,486
|
|
G
|
Rab29
|
RAB29, member RAS oncogene family
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of RAB29 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr13:45,859,930...45,865,468
Ensembl chr13:43,307,775...43,313,417
|
|
G
|
Rab30
|
RAB30, member RAS oncogene family
|
increases expression
|
ISO
|
Thimerosal results in increased expression of RAB30 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 1:146,803,719...146,898,369
Ensembl chr 1:146,803,714...146,892,181
|
|
G
|
Rab3b
|
RAB3B, member RAS oncogene family
|
affects expression
|
ISO
|
Thimerosal affects the expression of RAB3B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:123,629,562...123,697,410
Ensembl chr 5:123,644,423...123,697,401
|
|
G
|
Rab3gap1
|
RAB3 GTPase activating protein catalytic subunit 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of RAB3GAP1 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr13:41,908,179...41,981,611
Ensembl chr13:39,352,247...39,429,169
|
|
G
|
Rabl3
|
RAB, member of RAS oncogene family-like 3
|
increases expression
|
ISO
|
Thimerosal results in increased expression of RABL3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr11:76,658,723...76,687,681
Ensembl chr11:63,152,792...63,182,671
|
|
G
|
Rad18
|
RAD18 E3 ubiquitin protein ligase
|
increases expression
|
ISO
|
Thimerosal results in increased expression of RAD18 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:147,291,463...147,376,904
Ensembl chr 4:145,735,654...145,821,069
|
|
G
|
Rad23a
|
RAD23 homolog A, nucleotide excision repair protein
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of RAD23A mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr19:40,219,235...40,225,543
Ensembl chr19:23,314,797...23,320,695
|
|
G
|
Ralgapa2
|
Ral GTPase activating protein catalytic subunit alpha 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of RALGAPA2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:133,658,725...133,938,821
Ensembl chr 3:133,659,761...133,938,916
|
|
G
|
Rapgef2
|
Rap guanine nucleotide exchange factor 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of RAPGEF2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:166,505,868...166,728,139
Ensembl chr 2:164,207,513...164,244,247
|
|
G
|
Rapgef5
|
Rap guanine nucleotide exchange factor 5
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of RAPGEF5 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:138,445,184...138,679,943
Ensembl chr 6:138,437,991...138,679,936
|
|
G
|
Rapgefl1
|
Rap guanine nucleotide exchange factor like 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of RAPGEFL1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:83,793,711...83,810,373
Ensembl chr10:83,793,694...83,810,371
|
|
G
|
Rarres1
|
retinoic acid receptor responder 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of RARRES1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:151,749,715...151,783,975
Ensembl chr 2:151,749,715...151,783,978
|
|
G
|
Rasa2
|
RAS p21 protein activator 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of RASA2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:105,996,797...106,116,285
Ensembl chr 8:97,118,802...97,236,671
|
|
G
|
Rasgef1a
|
RasGEF domain family, member 1A
|
increases expression decreases expression
|
ISO
|
Thimerosal results in increased expression of RASGEF1A mRNA Thimerosal results in decreased expression of RASGEF1A mRNA
|
CTD |
PMID:24675092 PMID:27188386 |
|
NCBI chr 4:151,187,533...151,267,982
Ensembl chr 4:151,225,856...151,267,995
|
|
G
|
Rassf4
|
Ras association domain family member 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of RASSF4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:149,897,525...149,932,658
Ensembl chr 4:149,897,543...149,932,411
|
|
G
|
Rassf8
|
Ras association domain family member 8
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of RASSF8 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:178,716,110...178,798,042
Ensembl chr 4:178,719,992...178,796,690
|
|
G
|
Rbak
|
RB-associated KRAB zinc finger
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of RBAK mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr12:11,375,314...11,388,937
Ensembl chr12:11,375,318...11,388,934
|
|
G
|
Rbfox3
|
RNA binding fox-1 homolog 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of RBFOX3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:103,720,355...104,157,277
Ensembl chr10:103,720,636...104,156,935
|
|
G
|
Rbm22
|
RNA binding motif protein 22
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of RBM22 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr18:54,013,374...54,024,182
Ensembl chr18:54,013,351...54,024,569
|
|
G
|
Rbm26
|
RNA binding motif protein 26
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of RBM26 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr15:81,884,783...81,964,245
Ensembl chr15:81,887,219...81,964,118
|
|
G
|
Rbm7
|
RNA binding motif protein 7
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of RBM7 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 8:48,831,894...48,838,399
Ensembl chr 8:48,831,894...48,838,411
|
|
G
|
Rbm8a
|
RNA binding motif protein 8A
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of RBM8A mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:184,165,189...184,167,959
Ensembl chr 2:184,165,193...184,167,959
|
|
G
|
Rbpj
|
recombination signal binding protein for immunoglobulin kappa J region
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of RBPJ mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr14:61,551,366...61,736,220
Ensembl chr14:57,338,507...57,523,353
|
|
G
|
Rbpms2
|
RNA binding protein, mRNA processing factor 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of RBPMS2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:66,153,169...66,184,278
Ensembl chr 8:66,153,593...66,184,268
|
|
G
|
Rcan3
|
RCAN family member 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of RCAN3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:147,650,935...147,671,881
Ensembl chr 5:147,655,085...147,671,937
|
|
G
|
Rcor2
|
REST corepressor 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of RCOR2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:213,882,585...213,890,022
Ensembl chr 1:204,454,360...204,460,838
|
|
G
|
Reep6
|
receptor accessory protein 6
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of REEP6 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:10,024,601...10,031,507
Ensembl chr 7:9,373,927...9,380,597
|
|
G
|
Rell1
|
RELT-like 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of RELL1 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr14:44,318,640...44,378,541
Ensembl chr14:44,303,009...44,378,500
|
|
G
|
Reps1
|
RALBP1 associated Eps domain containing 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of REPS1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:14,517,589...14,595,404
Ensembl chr 1:12,697,747...12,775,561
|
|
G
|
Rfc1
|
replication factor C subunit 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of RFC1 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr14:42,966,279...43,041,372
Ensembl chr14:42,966,324...43,041,370
|
|
G
|
Rfx7
|
regulatory factor X, 7
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of RFX7 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:73,254,051...73,339,209
Ensembl chr 8:73,254,051...73,339,209
|
|
G
|
Rhobtb2
|
Rho-related BTB domain containing 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of RHOBTB2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr15:44,868,251...44,888,436
Ensembl chr15:44,870,376...44,888,651
|
|
G
|
Rhobtb3
|
Rho-related BTB domain containing 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of RHOBTB3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:5,363,388...5,419,164
Ensembl chr 2:5,363,388...5,419,041
|
|
G
|
Rhou
|
ras homolog family member U
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of RHOU mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr19:51,641,476...51,651,249
Ensembl chr19:51,641,227...51,650,552
|
|
G
|
Rimkla
|
ribosomal modification protein rimK-like family member A
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of RIMKLA mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:133,072,179...133,098,840
Ensembl chr 5:133,073,960...133,098,792
|
|
G
|
Rims1
|
regulating synaptic membrane exocytosis 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of RIMS1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:24,696,959...25,196,404
Ensembl chr 9:24,698,854...25,196,631
|
|
G
|
Rlig1
|
RNA 5'-phosphate and 3'-OH ligase 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of RLIG1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:35,396,876...35,408,633
Ensembl chr 7:35,397,995...35,409,600
|
|
G
|
Rnase4
|
ribonuclease A family member 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of RNASE4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr15:26,786,287...26,803,634
Ensembl chr15:24,312,464...24,330,117
|
|
G
|
Rnaset2
|
ribonuclease T2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of RNASET2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:52,576,344...52,603,151
Ensembl chr 1:52,585,929...52,603,147
|
|
G
|
Rnf130
|
ring finger protein 130
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of RNF130 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:34,342,835...34,456,048
Ensembl chr10:34,342,830...34,456,062
|
|
G
|
Rnf43
|
ring finger protein 43
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of RNF43 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:72,461,508...72,537,301
Ensembl chr10:72,464,348...72,536,977
|
|
G
|
Rnmt
|
RNA (guanine-7-) methyltransferase
|
increases expression
|
ISO
|
Thimerosal results in increased expression of RNMT mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr18:61,886,230...61,909,775
Ensembl chr18:61,886,292...61,909,775
|
|
G
|
Rora
|
RAR-related orphan receptor A
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of RORA mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:78,182,710...78,915,730
Ensembl chr 8:69,301,733...70,025,931
|
|
G
|
Rpl7
|
ribosomal protein L7
|
increases expression
|
ISO
|
Thimerosal results in increased expression of RPL7 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:3,217,184...3,220,192
|
|
G
|
Rps23
|
ribosomal protein S23
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of RPS23 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:22,079,339...22,080,909
Ensembl chr 2:22,079,302...22,080,918
|
|
G
|
Rps27l
|
ribosomal protein S27-like
|
increases expression
|
ISO
|
Thimerosal results in increased expression of RPS27L mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418 Ensembl chr12:67,562,483...67,567,418 Ensembl chr 2:67,562,483...67,567,418
|
|
G
|
Rrad
|
RRAD, Ras related glycolysis inhibitor and calcium channel regulator
|
increases expression
|
ISO
|
Thimerosal results in increased expression of RRAD mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr19:360,581...363,874
Ensembl chr19:354,198...357,417
|
|
G
|
Rsph9
|
radial spoke head component 9
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of RSPH9 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:14,840,115...14,852,950
Ensembl chr 9:14,840,115...14,860,062
|
|
G
|
RT1-A2
|
RT1 class Ia, locus A2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of HLA-E mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr20:4,872,720...4,876,425
|
|
G
|
RT1-CE16
|
RT1 class I, locus CE16
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of HLA-A mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr20:3,261,656...3,265,548
Ensembl chr20:3,257,123...3,279,563
|
|
G
|
RT1-Hb-ps1
|
RT1 class II, locus Hb, pseudogene 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of HLA-DPB1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr20:4,775,598...4,779,590
Ensembl chr20:4,774,650...4,780,618
|
|
G
|
Rtl8a
|
retrotransposon Gag like 8A
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of RTL8A mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr X:133,414,027...133,415,240
Ensembl chr X:133,414,030...133,415,240
|
|
G
|
Rtn4r
|
reticulon 4 receptor
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of RTN4R mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr11:96,348,613...96,373,554
Ensembl chr11:82,844,309...82,869,466
|
|
G
|
Rufy2
|
RUN and FYVE domain containing 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of RUFY2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr20:25,626,958...25,658,157
Ensembl chr20:25,621,999...25,658,186
|
|
G
|
Rusc2
|
RUN and SH3 domain containing 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of RUSC2 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 5:62,424,185...62,471,317
Ensembl chr 5:57,629,904...57,675,524
|
|
G
|
Ryr3
|
ryanodine receptor 3
|
increases expression
|
ISO
|
Thimerosal results in increased expression of RYR3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:99,431,755...99,979,125
Ensembl chr 3:99,432,505...99,704,961
|
|
G
|
Sall4
|
spalt-like transcription factor 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SALL4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:157,474,067...157,491,055
Ensembl chr 3:157,474,642...157,490,822
|
|
G
|
Samhd1
|
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SAMHD1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:145,761,549...145,794,420
Ensembl chr 3:145,761,558...145,794,386
|
|
G
|
Sapcd2
|
suppressor APC domain containing 2
|
multiple interactions
|
ISO
|
[NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SAPCD2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:8,186,089...8,195,119
Ensembl chr 3:8,187,266...8,192,546
|
|
G
|
Sar1b
|
secretion associated, Ras related GTPase 1B
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SAR1B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:36,024,415...36,054,069
Ensembl chr10:36,024,382...36,054,066
|
|
G
|
Sav1
|
salvador family WW domain containing protein 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SAV1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:88,478,536...88,500,121
Ensembl chr 6:88,478,539...88,499,968
|
|
G
|
Saxo2
|
stabilizer of axonemal microtubules 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SAXO2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:136,596,445...136,638,444
Ensembl chr 1:136,623,493...136,638,454
|
|
G
|
Scd
|
stearoyl-CoA desaturase
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SCD mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:243,269,747...243,282,562
|
|
G
|
Scoc
|
short coiled-coil protein
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SCOC mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr19:24,659,651...24,689,237
Ensembl chr19:24,659,651...24,693,217
|
|
G
|
Scrn3
|
secernin 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SCRN3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:58,188,820...58,213,623
Ensembl chr 3:58,188,889...58,213,623
|
|
G
|
Scrt1
|
scratch family transcriptional repressor 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SCRT1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:110,121,640...110,125,290
Ensembl chr 7:108,240,986...108,244,636
|
|
G
|
Scyl2
|
SCY1 like pseudokinase 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SCYL2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:24,064,404...24,117,338
Ensembl chr 7:24,064,404...24,117,305
|
|
G
|
Sdc1
|
syndecan 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SDC1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:37,282,041...37,304,503
Ensembl chr 6:31,562,739...31,585,264
|
|
G
|
Secisbp2l
|
SECIS binding protein 2-like
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SECISBP2L mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:133,443,023...133,489,467
Ensembl chr 3:112,991,908...113,035,884
|
|
G
|
Sel1l
|
SEL1L adaptor subunit of SYVN1 ubiquitin ligase
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SEL1L mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:116,466,163...116,510,436
Ensembl chr 6:110,735,450...110,779,648
|
|
G
|
Sema3f
|
semaphorin 3F
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SEMA3F mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:117,236,269...117,265,206
Ensembl chr 8:108,357,629...108,387,083
|
|
G
|
Sema4f
|
semaphorin 4F
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SEMA4F mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:115,411,411...115,437,721
Ensembl chr 4:115,411,417...115,437,721
|
|
G
|
Sema6a
|
semaphorin 6A
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SEMA6A mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr18:40,050,623...40,171,954
Ensembl chr18:40,050,624...40,171,954
|
|
G
|
Senp7
|
SUMO specific peptidase 7
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SENP7 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr11:44,423,733...44,584,129
Ensembl chr11:44,423,735...44,564,711
|
|
G
|
Sepsecs
|
Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
|
increases expression multiple interactions
|
ISO
|
Thimerosal results in increased expression of SEPSECS mRNA [NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SEPSECS mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr14:58,311,484...58,341,745
Ensembl chr14:58,311,499...58,341,740
|
|
G
|
Septin9
|
septin 9
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SEPTIN9 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:102,409,798...102,579,056
Ensembl chr10:102,409,711...102,579,055
|
|
G
|
Serinc2
|
serine incorporator 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SERINC2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:142,592,308...142,614,628
Ensembl chr 5:142,592,309...142,618,364
|
|
G
|
Serpine1
|
serpin family E member 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SERPINE1 mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr12:25,237,977...25,248,356
Ensembl chr12:19,601,272...19,611,657
|
|
G
|
Serpinh1
|
serpin family H member 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SERPINH1 mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr 1:163,055,630...163,063,177
Ensembl chr 1:153,643,510...153,650,801
|
|
G
|
Setd2
|
SET domain containing 2, histone lysine methyltransferase
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SETD2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:119,390,207...119,475,863
Ensembl chr 8:110,511,772...110,597,489
|
|
G
|
Setd9-ps1
|
SET domain containing, pseudogene 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SETD9 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:43,319,359...43,322,764
|
|
G
|
Setx
|
senataxin
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SETX mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:12,428,091...12,480,801
Ensembl chr 3:12,427,635...12,480,803
|
|
G
|
Sez6l2
|
seizure related 6 homolog like 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SEZ6L2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:181,557,109...181,577,456
Ensembl chr 1:181,557,109...181,577,456
|
|
G
|
Sf3a2
|
splicing factor 3A subunit 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SF3A2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:8,909,507...8,916,104
Ensembl chr 7:8,909,507...8,915,530
|
|
G
|
Sf3b1
|
splicing factor 3b, subunit 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SF3B1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:56,492,403...56,532,300
Ensembl chr 9:56,492,403...56,532,300
|
|
G
|
Sf3b4
|
splicing factor 3B subunit 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SF3B4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:183,732,791...183,737,545
Ensembl chr 2:183,732,754...183,737,959
|
|
G
|
Sfpq
|
splicing factor proline and glutamine rich
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SFPQ mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:144,621,678...144,637,930
Ensembl chr 5:139,338,075...139,353,472
|
|
G
|
Sfr1
|
SWI5-dependent homologous recombination repair protein 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SFR1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:246,619,235...246,623,250
Ensembl chr 1:246,597,044...246,623,250
|
|
G
|
Sfrp1
|
secreted frizzled-related protein 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SFRP1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr16:75,278,325...75,316,736
Ensembl chr16:68,575,763...68,614,286
|
|
G
|
Sgpl1
|
sphingosine-1-phosphate lyase 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SGPL1 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr20:29,047,793...29,094,209
Ensembl chr20:29,047,796...29,094,084
|
|
G
|
Sh3bgrl3
|
SH3 domain binding glutamate-rich protein like 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SH3BGRL3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:146,354,152...146,355,525
Ensembl chr 5:146,354,152...146,355,331
|
|
G
|
Shfl
|
shiftless antiviral inhibitor of ribosomal frameshifting
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SHFL mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:27,683,560...27,690,269
Ensembl chr 8:19,408,333...19,413,971
|
|
G
|
Shisa5
|
shisa family member 5
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SHISA5 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:109,691,504...109,706,411
Ensembl chr 8:109,691,522...109,706,408
|
|
G
|
Shoc2
|
SHOC2 leucine-rich repeat scaffold protein
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SHOC2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:252,958,939...253,048,820
Ensembl chr 1:252,959,723...253,047,337
|
|
G
|
Siah1
|
siah E3 ubiquitin protein ligase 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SIAH1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr19:20,378,908...20,402,512
Ensembl chr19:20,378,439...20,403,808
|
|
G
|
Sike1
|
suppressor of IKBKE 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SIKE1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:190,518,002...190,525,833
Ensembl chr 2:190,518,002...190,525,832
|
|
G
|
Sipa1
|
signal-induced proliferation-associated 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SIPA1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:202,938,532...202,950,672
Ensembl chr 1:202,938,580...202,950,591
|
|
G
|
Sirpa
|
signal-regulatory protein alpha
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SIRPA mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:137,272,932...137,311,279
Ensembl chr 3:116,819,726...116,858,098
|
|
G
|
Sirt1
|
sirtuin 1
|
multiple interactions
|
ISO
|
SIRT1 protein affects the reaction [Resveratrol inhibits the reaction [[SOD1 protein results in increased susceptibility to Thimerosal] which results in decreased expression of KCNIP3 protein]]
|
CTD |
PMID:30503815 |
|
NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,306,917...25,329,260
|
|
G
|
Six5
|
SIX homeobox 5
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SIX5 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:87,868,859...87,873,929
Ensembl chr 1:78,741,367...78,745,890
|
|
G
|
Six6
|
SIX homeobox 6
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SIX6 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 6:91,634,568...91,639,548
Ensembl chr 6:91,634,568...91,639,548
|
|
G
|
Ska2
|
spindle and kinetochore associated complex subunit 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SKA2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:71,921,474...71,939,461
Ensembl chr10:71,921,582...71,939,458
|
|
G
|
Skic3
|
SKI3 subunit of superkiller complex
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SKIC3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:5,631,544...5,783,643
Ensembl chr 2:5,631,635...5,751,626
|
|
G
|
Slc10a7
|
solute carrier family 10, member 7
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SLC10A7 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr19:29,183,143...29,407,470
Ensembl chr19:29,183,155...29,407,464
|
|
G
|
Slc12a2
|
solute carrier family 12 member 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SLC12A2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440
|
|
G
|
Slc16a1
|
solute carrier family 16 member 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SLC16A1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:194,805,556...194,832,966
Ensembl chr 2:192,124,289...192,144,611
|
|
G
|
Slc16a14
|
solute carrier family 16, member 14
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SLC16A14 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:93,558,144...93,585,396
Ensembl chr 9:86,112,894...86,137,318
|
|
G
|
Slc16a6
|
solute carrier family 16, member 6
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SLC16A6 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:94,923,888...94,946,990
Ensembl chr10:94,426,244...94,448,779
|
|
G
|
Slc16a9
|
solute carrier family 16, member 9
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SLC16A9 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr20:18,334,946...18,376,195
Ensembl chr20:18,335,862...18,377,022
|
|
G
|
Slc18b1
|
solute carrier family 18 member B1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SLC18B1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:21,628,235...21,670,807
Ensembl chr 1:21,628,237...21,670,684
|
|
G
|
Slc1a1
|
solute carrier family 1 member 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SLC1A1 protein
|
CTD |
PMID:15184908 |
|
NCBI chr 1:235,963,455...236,043,572
Ensembl chr 1:226,549,842...226,630,402
|
|
G
|
Slc22a4
|
solute carrier family 22 member 4
|
decreases activity
|
ISO
|
Thimerosal results in decreased activity of SLC22A4 protein
|
CTD |
PMID:25490951 |
|
NCBI chr10:38,133,333...38,179,932
Ensembl chr10:38,133,322...38,179,720
|
|
G
|
Slc25a1
|
solute carrier family 25 member 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SLC25A1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr11:83,055,764...83,058,781
Ensembl chr11:83,055,748...83,058,781
|
|
G
|
Slc25a21
|
solute carrier family 25 member 21
|
multiple interactions
|
ISO
|
[NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC25A21 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:74,203,439...74,702,902
Ensembl chr 6:74,203,440...74,702,680
|
|
G
|
Slc25a23
|
solute carrier family 25 member 23
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SLC25A23 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:1,882,636...1,898,369
Ensembl chr 9:1,882,621...1,898,561
|
|
G
|
Slc25a44
|
solute carrier family 25, member 44
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SLC25A44 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:173,868,317...173,883,137
Ensembl chr 2:173,868,320...173,883,020
|
|
G
|
Slc29a2
|
solute carrier family 29 member 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SLC29A2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:211,756,588...211,764,561
Ensembl chr 1:202,327,354...202,335,171
|
|
G
|
Slc2a1
|
solute carrier family 2 member 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SLC2A1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:138,002,522...138,030,742
Ensembl chr 5:132,717,196...132,745,416
|
|
G
|
Slc2a12
|
solute carrier family 2 member 12
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SLC2A12 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:24,623,558...24,683,577
Ensembl chr 1:22,804,418...22,860,971
|
|
G
|
Slc2a3
|
solute carrier family 2 member 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SLC2A3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:157,632,887...157,698,034
Ensembl chr 4:155,960,946...156,025,472
|
|
G
|
Slc30a5
|
solute carrier family 30 member 5
|
multiple interactions
|
ISO
|
[NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC30A5 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:31,945,745...31,975,969
Ensembl chr 2:31,945,729...31,975,934
|
|
G
|
Slc38a1
|
solute carrier family 38, member 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SLC38A1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:129,612,414...129,681,727
Ensembl chr 7:127,738,226...127,802,218
|
|
G
|
Slc5a3
|
solute carrier family 5 member 3
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SLC5A3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr11:31,313,847...31,316,293
Ensembl chr11:31,295,476...31,318,883
|
|
G
|
Slc5a7
|
solute carrier family 5 member 7
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SLC5A7 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:7,595,440...7,626,258
Ensembl chr 9:7,595,444...7,626,258
|
|
G
|
Slc6a3
|
solute carrier family 6 member 3
|
increases expression multiple interactions
|
ISO
|
Thimerosal results in increased expression of SLC6A3 protein [Thimerosal co-treated with Aluminum Hydroxide] results in increased expression of SLC6A3 protein
|
CTD |
PMID:36411272 |
|
NCBI chr 1:31,537,990...31,578,962
Ensembl chr 1:29,709,443...29,750,413
|
|
G
|
Slc7a1
|
solute carrier family 7 member 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SLC7A1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr12:6,628,288...6,703,849
Ensembl chr12:6,628,007...6,703,849
|
|
G
|
Slc7a3
|
solute carrier family 7 member 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SLC7A3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr X:66,210,071...66,216,482
Ensembl chr X:66,210,081...66,215,708
|
|
G
|
Slc8a1
|
solute carrier family 8 member A1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SLC8A1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:13,194,609...13,547,369
Ensembl chr 6:13,194,662...13,535,628
|
|
G
|
Smarcc2
|
SWI/SNF related BAF chromatin remodeling complex subunit C2
|
affects expression
|
ISO
|
Thimerosal affects the expression of SMARCC2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:881,844...910,090
Ensembl chr 7:881,421...909,978
|
|
G
|
Smc1a
|
structural maintenance of chromosomes 1A
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SMC1A mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr X:21,103,323...21,148,053
Ensembl chr X:21,103,282...21,148,056
|
|
G
|
Smchd1
|
structural maintenance of chromosomes flexible hinge domain containing 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SMCHD1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:111,243,445...111,387,272
Ensembl chr 9:111,247,702...111,349,665
|
|
G
|
Smim3
|
small integral membrane protein 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SMIM3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr18:53,930,019...53,982,339
Ensembl chr18:53,930,020...53,957,416
|
|
G
|
Smox
|
spermine oxidase
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SMOX mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:139,184,793...139,220,174
Ensembl chr 3:118,731,900...118,765,710 Ensembl chr X:118,731,900...118,765,710
|
|
G
|
Snap25
|
synaptosome associated protein 25
|
decreases expression
|
EXP
|
Thimerosal results in decreased expression of SNAP25 protein
|
CTD |
PMID:27693314 |
|
NCBI chr 3:144,494,579...144,576,449
Ensembl chr 3:124,041,898...124,123,760
|
|
G
|
Sncaip
|
synuclein, alpha interacting protein
|
multiple interactions
|
ISO
|
[NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SNCAIP mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr18:48,402,164...48,542,246
Ensembl chr18:46,207,152...46,343,929
|
|
G
|
Snrpa
|
small nuclear ribonucleoprotein polypeptide A
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SNRPA mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:91,609,419...91,618,119
Ensembl chr 1:82,481,770...82,490,538
|
|
G
|
Snx2
|
sorting nexin 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SNX2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr18:46,602,223...46,643,870
Ensembl chr18:46,602,284...46,643,865
|
|
G
|
Snx21
|
sorting nexin family member 21
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SNX21 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:153,522,474...153,532,235
Ensembl chr 3:153,522,486...153,532,221
|
|
G
|
Snx4
|
sorting nexin 4
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SNX4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr11:67,460,872...67,518,143
Ensembl chr11:67,460,870...67,518,174
|
|
G
|
Snx9
|
sorting nexin 9
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SNX9 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:46,424,897...46,510,096
Ensembl chr 1:46,423,553...46,509,036
|
|
G
|
Sod1
|
superoxide dismutase 1
|
multiple interactions increases response to substance
|
ISO
|
[SOD1 protein mutant form results in increased susceptibility to Thimerosal] which results in increased acetylation of and results in increased ubiquitination of KCNIP3 protein; [SOD1 protein mutant form results in increased susceptibility to Thimerosal] which results in increased expression of PDYN mRNA; [SOD1 protein results in increased susceptibility to Thimerosal] which results in decreased expression of KCNIP3 protein; [SOD1 protein results in increased susceptibility to Thimerosal] which results in increased cleavage of CASP3 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[SOD1 protein results in increased susceptibility to Thimerosal] which results in decreased expression of KCNIP3 protein]; Resveratrol inhibits the reaction [[SOD1 protein mutant form results in increased susceptibility to Thimerosal] which results in increased acetylation of and results in increased ubiquitination of KCNIP3 protein]; Resveratrol inhibits the reaction [[SOD1 protein mutant form results in increased susceptibility to Thimerosal] which results in increased expression of PDYN mRNA]; Resveratrol inhibits the reaction [[SOD1 protein results in increased susceptibility to Thimerosal] which results in decreased expression of KCNIP3 protein]; Resveratrol inhibits the reaction [[SOD1 protein results in increased susceptibility to Thimerosal] which results in increased cleavage of CASP3 protein]; SIRT1 protein affects the reaction [Resveratrol inhibits the reaction [[SOD1 protein results in increased susceptibility to Thimerosal] which results in decreased expression of KCNIP3 protein]]
|
CTD |
PMID:30503815 |
|
NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249
|
|
G
|
Son
|
SON DNA and RNA binding protein
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SON mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr11:30,850,890...30,923,167
Ensembl chr11:30,892,005...30,923,167
|
|
G
|
Sorbs2
|
sorbin and SH3 domain containing 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SORBS2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr16:46,435,220...46,748,743
Ensembl chr16:46,435,237...46,626,514
|
|
G
|
Sorbs3
|
sorbin and SH3 domain containing 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SORBS3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr15:45,252,921...45,284,758
Ensembl chr15:45,253,379...45,284,758
|
|
G
|
Sorl1
|
sortilin related receptor 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SORL1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:51,238,713...51,401,458
Ensembl chr 8:42,341,704...42,504,513
|
|
G
|
Sox18
|
SRY-box transcription factor 18
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SOX18 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 3:168,785,488...168,787,290
Ensembl chr 3:168,785,490...168,787,290
|
|
G
|
Sox7
|
SRY-box transcription factor 7
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SOX7 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr15:38,180,503...38,187,264
Ensembl chr15:38,180,503...38,187,264
|
|
G
|
Sox8
|
SRY-box transcription factor 8
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SOX8 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:15,089,357...15,094,345
Ensembl chr10:14,584,829...14,589,818
|
|
G
|
Sox9
|
SRY-box transcription factor 9
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SOX9 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
|
|
G
|
Sp4
|
Sp4 transcription factor
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SP4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:139,187,458...139,252,741
Ensembl chr 6:139,192,147...139,252,126
|
|
G
|
Sp5
|
Sp5 transcription factor
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SP5 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:55,274,931...55,277,733
Ensembl chr 3:55,274,931...55,277,733
|
|
G
|
Sp8
|
Sp8 transcription factor
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SP8 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 6:139,816,258...139,818,865
Ensembl chr 6:139,814,819...139,823,168 Ensembl chr 6:139,814,819...139,823,168
|
|
G
|
Spag4
|
sperm associated antigen 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SPAG4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:144,581,006...144,587,879
Ensembl chr 3:144,581,095...144,585,435
|
|
G
|
Spag9
|
sperm associated antigen 9
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SPAG9 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:79,440,311...79,574,709
Ensembl chr10:78,943,479...79,077,797
|
|
G
|
Spata18
|
spermatogenesis associated 18
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SPATA18 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr14:34,531,931...34,558,671
Ensembl chr14:34,531,061...34,558,687
|
|
G
|
Spata2
|
spermatogenesis associated 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SPATA2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:156,202,962...156,213,283
Ensembl chr 3:156,202,967...156,211,705
|
|
G
|
Spatc1l
|
spermatogenesis and centriole associated 1-like
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SPATC1L mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr20:12,074,040...12,083,873
Ensembl chr20:12,074,047...12,083,301
|
|
G
|
Specc1
|
sperm antigen with calponin homology and coiled-coil domains 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SPECC1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:46,638,947...46,912,989
Ensembl chr10:46,638,809...46,912,802
|
|
G
|
Spen
|
spen family transcriptional repressor
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SPEN mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:153,775,287...153,848,677
Ensembl chr 5:153,776,234...153,848,811
|
|
G
|
Spmip4
|
sperm microtubule inner protein 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SPMIP4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:79,663,375...79,688,291
Ensembl chr 4:79,663,376...79,689,072
|
|
G
|
Sppl2b
|
signal peptide peptidase-like 2B
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SPPL2B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:8,843,918...8,856,642
Ensembl chr 7:8,843,918...8,856,608
|
|
G
|
Sptbn1
|
spectrin, beta, non-erythrocytic 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SPTBN1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr14:103,841,713...104,016,900
Ensembl chr14:103,842,684...104,008,507
|
|
G
|
Sqle
|
squalene epoxidase
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SQLE mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618
|
|
G
|
Srd5a3
|
steroid 5 alpha-reductase 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SRD5A3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr14:32,046,408...32,060,796
Ensembl chr14:32,046,408...32,060,747
|
|
G
|
Srl
|
sarcalumenin
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SRL mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr10:11,033,976...11,078,103
Ensembl chr10:11,034,035...11,078,101
|
|
G
|
Srpra
|
SRP receptor subunit alpha
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SRPRA mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:41,818,199...41,824,292
Ensembl chr 8:33,560,348...33,566,470
|
|
G
|
Srrm1
|
serine and arginine repetitive matrix 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SRRM1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:147,559,515...147,591,895
Ensembl chr 5:147,559,514...147,591,849
|
|
G
|
Srrm2
|
serine/arginine repetitive matrix 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SRRM2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:12,815,471...12,848,750
Ensembl chr10:12,815,471...12,848,751
|
|
G
|
Srsf4
|
serine and arginine rich splicing factor 4
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SRSF4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:144,060,981...144,090,798
Ensembl chr 5:144,061,463...144,089,229
|
|
G
|
Ssrp1
|
structure specific recognition protein 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SSRP1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:70,124,371...70,134,481
Ensembl chr 3:70,118,655...70,134,482
|
|
G
|
Stag1
|
STAG1 cohesin complex component
|
increases expression
|
ISO
|
Thimerosal results in increased expression of STAG1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:101,179,039...101,564,684
Ensembl chr 8:101,179,039...101,564,677
|
|
G
|
Stag2
|
STAG2 cohesin complex component
|
increases expression
|
ISO
|
Thimerosal results in increased expression of STAG2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr X:120,974,687...121,105,677
Ensembl chr X:120,974,857...121,105,677
|
|
G
|
Stat3
|
signal transducer and activator of transcription 3
|
multiple interactions decreases phosphorylation
|
ISO
|
[Thimerosal co-treated with Temozolomide] results in decreased phosphorylation of STAT3 protein Thimerosal results in decreased phosphorylation of STAT3 protein
|
CTD |
PMID:38325586 |
|
NCBI chr10:86,311,528...86,363,513
Ensembl chr10:85,811,218...85,863,057
|
|
G
|
Stc1
|
stanniocalcin 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of STC1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr15:44,299,591...44,311,695
Ensembl chr15:44,299,621...44,310,264
|
|
G
|
Stc2
|
stanniocalcin 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of STC2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:16,755,508...16,765,275
Ensembl chr10:16,250,853...16,262,973
|
|
G
|
Stim2
|
stromal interaction molecule 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of STIM2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr14:56,878,428...57,004,405
Ensembl chr14:56,878,645...57,004,179
|
|
G
|
Stk35
|
serine/threonine kinase 35
|
increases expression
|
ISO
|
Thimerosal results in increased expression of STK35 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:137,465,884...137,498,554
Ensembl chr 3:117,016,950...117,048,066
|
|
G
|
Ston2
|
stonin 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of STON2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:110,567,485...110,676,376
Ensembl chr 6:110,567,485...110,676,376
|
|
G
|
Stpg1
|
sperm-tail PG-rich repeat containing 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of STPG1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:147,717,084...147,769,792
Ensembl chr 5:147,726,646...147,769,788
|
|
G
|
Stx2
|
syntaxin 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of STX2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr12:27,678,744...27,714,751
Ensembl chr12:27,689,819...27,714,751
|
|
G
|
Stx4
|
syntaxin 4
|
increases expression
|
ISO
|
Thimerosal results in increased expression of STX4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:182,451,108...182,459,701
Ensembl chr 1:182,451,117...182,459,979
|
|
G
|
Styx
|
serine/threonine/tyrosine interacting protein
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of STYX mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr15:18,565,214...18,595,797
Ensembl chr15:18,564,633...18,593,524
|
|
G
|
Sun2
|
Sad1 and UNC84 domain containing 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SUN2 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 7:113,155,766...113,172,950
Ensembl chr 7:111,275,380...111,292,553
|
|
G
|
Supt16h
|
SPT16 homolog, facilitates chromatin remodeling subunit
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SUPT16H mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr15:24,867,697...24,904,818
Ensembl chr15:24,866,489...24,904,846
|
|
G
|
Sycp2
|
synaptonemal complex protein 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SYCP2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:165,431,715...165,502,134
Ensembl chr 3:165,436,331...165,498,789
|
|
G
|
Sycp3
|
synaptonemal complex protein 3
|
increases expression
|
ISO
|
Thimerosal results in increased expression of SYCP3 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 7:22,874,055...22,888,512
Ensembl chr 7:22,874,055...22,888,511
|
|
G
|
Syncrip
|
synaptotagmin binding, cytoplasmic RNA interacting protein
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SYNCRIP mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:89,402,487...89,435,517
Ensembl chr 8:89,402,866...89,435,515
|
|
G
|
Syne2
|
spectrin repeat containing nuclear envelope protein 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SYNE2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:94,537,088...94,848,085
Ensembl chr 6:94,537,088...94,848,064
|
|
G
|
Syngr3
|
synaptogyrin 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SYNGR3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:13,710,553...13,715,309
Ensembl chr10:13,704,998...13,715,669
|
|
G
|
Synj2bp
|
synaptojanin 2 binding protein
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SYNJ2BP mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:106,920,970...106,958,653
Ensembl chr 6:101,189,714...101,227,406
|
|
G
|
Syt6
|
synaptotagmin 6
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SYT6 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:191,093,009...191,152,283
Ensembl chr 2:191,093,007...191,149,956
|
|
G
|
Sytl4
|
synaptotagmin-like 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of SYTL4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr X:97,135,496...97,185,867
Ensembl chr X:97,135,500...97,185,854
|
|
G
|
Taf9
|
TATA-box binding protein associated factor 9
|
increases expression
|
ISO
|
Thimerosal results in increased expression of TAF9 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:31,794,316...31,798,324
Ensembl chr 2:31,794,142...31,798,769
|
|
G
|
Taf9b
|
TATA-box binding protein associated factor 9b
|
affects expression
|
ISO
|
Thimerosal affects the expression of TAF9B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr X:71,289,290...71,300,142
Ensembl chr X:71,289,290...71,300,604
|
|
G
|
Tanc2
|
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TANC2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:90,553,124...90,873,477
Ensembl chr10:90,553,002...90,868,756
|
|
G
|
Taok1
|
TAO kinase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TAOK1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:62,871,198...62,989,049
Ensembl chr10:62,381,404...62,465,766
|
|
G
|
Tap2
|
transporter 2, ATP binding cassette subfamily B member
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TAP2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr20:4,638,257...4,652,296
Ensembl chr20:4,636,357...4,650,407
|
|
G
|
Tasor2
|
transcription activation suppressor family member 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of TASOR2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr17:66,583,554...66,650,127
Ensembl chr17:66,594,908...66,649,135
|
|
G
|
Tax1bp1
|
Tax1 binding protein 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of TAX1BP1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:81,821,991...81,877,906
Ensembl chr 4:81,821,989...81,879,100
|
|
G
|
Tbc1d16
|
TBC1 domain family, member 16
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TBC1D16 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:104,400,963...104,486,698
Ensembl chr10:104,402,398...104,486,670
|
|
G
|
Tbc1d8b
|
TBC1 domain family member 8B
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TBC1D8B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr X:103,319,181...103,407,137
Ensembl chr X:103,319,340...103,407,133
|
|
G
|
Tbl1x
|
transducin (beta)-like 1 X-linked
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TBL1X mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr X:41,574,558...41,731,117
Ensembl chr X:41,576,047...41,731,101
|
|
G
|
Tbl1xr1
|
TBL1X/Y related 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of TBL1XR1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:104,788,950...104,929,055
Ensembl chr 2:104,801,721...104,929,055
|
|
G
|
Tbrg4
|
transforming growth factor beta regulator 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TBRG4 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr14:81,481,977...81,490,781
Ensembl chr14:81,481,981...81,490,756
|
|
G
|
Tcf7l1
|
transcription factor 7 like 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TCF7L1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:104,680,734...104,846,086
Ensembl chr 4:104,680,739...104,845,287
|
|
G
|
Tdrd6
|
tudor domain containing 6
|
increases expression
|
ISO
|
Thimerosal results in increased expression of TDRD6 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:17,344,033...17,359,348
Ensembl chr 9:17,344,026...17,359,344
|
|
G
|
Tdrd7
|
tudor domain containing 7
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TDRD7 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:60,238,742...60,312,548
Ensembl chr 5:60,238,678...60,312,544
|
|
G
|
Tdrkh
|
tudor and KH domain containing
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TDRKH mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:182,049,175...182,071,516
Ensembl chr 2:182,049,215...182,070,755
|
|
G
|
Tead1
|
TEA domain transcription factor 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TEAD1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:166,791,900...167,010,591
Ensembl chr 1:166,792,628...167,003,369
|
|
G
|
Tecr
|
trans-2,3-enoyl-CoA reductase
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TECR mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr19:41,431,422...41,472,880
Ensembl chr19:24,541,615...24,568,168
|
|
G
|
Tet1
|
tet methylcytosine dioxygenase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TET1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr20:25,766,806...25,839,598
Ensembl chr20:25,768,120...25,833,052
|
|
G
|
Tet2
|
tet methylcytosine dioxygenase 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TET2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:224,662,654...224,746,819
Ensembl chr 2:221,988,645...222,072,534
|
|
G
|
Tet3
|
tet methylcytosine dioxygenase 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TET3 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 4:117,425,106...117,525,495
Ensembl chr 4:115,871,265...115,964,193
|
|
G
|
Tex10
|
testis expressed 10
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TEX10 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:62,762,230...62,808,373
Ensembl chr 5:62,762,230...62,808,373
|
|
G
|
Tgfb1
|
transforming growth factor, beta 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of TGFB1
|
CTD |
PMID:24942245 |
|
NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847
|
|
G
|
Them4
|
thioesterase superfamily member 4
|
increases expression
|
ISO
|
Thimerosal results in increased expression of THEM4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:181,953,550...181,974,708
Ensembl chr 2:181,953,550...181,974,708
|
|
G
|
Themis2
|
thymocyte selection associated family member 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of THEMIS2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:144,991,110...145,006,362
Ensembl chr 5:144,991,112...145,006,400
|
|
G
|
Thpo
|
thrombopoietin
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of THPO mRNA
|
CTD |
PMID:24675092 |
|
Ensembl chr11:80,182,820...80,188,167
|
|
G
|
Thrap3
|
thyroid hormone receptor associated protein 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of THRAP3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:138,445,284...138,487,544
Ensembl chr 5:138,445,295...138,487,477
|
|
G
|
Thy1
|
Thy-1 cell surface antigen
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of THY1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659
|
|
G
|
Tkt
|
transketolase
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TKT mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,723,762...5,748,698
|
|
G
|
Tle4
|
TLE family member 4, transcriptional corepressor
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TLE4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:221,086,250...221,222,826
Ensembl chr 1:211,661,746...211,797,862
|
|
G
|
Tmc5
|
transmembrane channel-like 5
|
multiple interactions
|
ISO
|
[NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TMC5 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:172,914,915...172,999,478
Ensembl chr 1:172,914,457...172,999,474
|
|
G
|
Tmc6
|
transmembrane channel like 6
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TMC6 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:103,480,762...103,498,207
Ensembl chr10:102,971,229...102,998,960
|
|
G
|
Tmeff2
|
transmembrane protein with EGF-like and two follistatin-like domains 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of TMEFF2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:50,445,947...50,733,473
Ensembl chr 9:50,436,079...50,733,475
|
|
G
|
Tmem240
|
transmembrane protein 240
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TMEM240 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 5:166,344,000...166,350,210
Ensembl chr 5:166,344,386...166,350,636
|
|
G
|
Tmem33
|
transmembrane protein 33
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TMEM33 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr14:40,888,485...40,910,715
Ensembl chr14:40,885,712...40,910,715
|
|
G
|
Tmem74b
|
transmembrane protein 74B
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TMEM74B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:140,219,592...140,224,208
Ensembl chr 3:140,219,412...140,235,872
|
|
G
|
Tmem97
|
transmembrane protein 97
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TMEM97 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:63,438,228...63,447,311
Ensembl chr10:63,438,222...63,589,730
|
|
G
|
Tmod2
|
tropomodulin 2
|
increases expression
|
ISO
|
Thimerosal results in increased expression of TMOD2 mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr 8:76,316,736...76,366,003
Ensembl chr 8:76,325,667...76,365,720
|
|
G
|
Tmtc3
|
transmembrane O-mannosyltransferase targeting cadherins 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TMTC3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:35,264,886...35,310,010
Ensembl chr 7:35,264,892...35,310,385
|
|
G
|
Tnf
|
tumor necrosis factor
|
increases secretion multiple interactions
|
ISO
|
Thimerosal results in increased secretion of TNF protein Glutathione inhibits the reaction [Thimerosal inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]; Thimerosal inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
|
CTD |
PMID:17079650 PMID:18495191 PMID:20417223 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
|
|
G
|
Tnfsf13b
|
TNF superfamily member 13b
|
increases expression
|
ISO
|
Thimerosal results in increased expression of TNFSF13B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr16:86,164,377...86,195,072
Ensembl chr16:79,462,402...79,492,693
|
|
G
|
Tnip1
|
TNFAIP3 interacting protein 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TNIP1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:39,037,048...39,084,328
Ensembl chr10:39,037,058...39,077,625
|
|
G
|
Tnni3
|
troponin I3, cardiac type
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TNNI3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:69,299,900...69,303,582
Ensembl chr 1:69,299,900...69,303,580
|
|
G
|
Tob2
|
transducer of ERBB2, 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TOB2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 7:115,242,843...115,251,563
Ensembl chr 7:113,361,148...113,372,688
|
|
G
|
Top2a
|
DNA topoisomerase II alpha
|
decreases activity
|
ISO
|
Thimerosal results in decreased activity of TOP2A protein
|
CTD |
PMID:18197631 |
|
NCBI chr10:84,441,954...84,473,093
Ensembl chr10:83,945,735...83,976,874
|
|
G
|
Tox2
|
TOX high mobility group box family member 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TOX2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:151,853,294...151,980,086
Ensembl chr 3:151,853,294...151,980,749
|
|
G
|
Tp53
|
tumor protein p53
|
affects activity
|
ISO
|
Thimerosal affects the activity of TP53 protein
|
CTD |
PMID:35435491 |
|
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524
|
|
G
|
Tp53bp1
|
tumor protein p53 binding protein 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TP53BP1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822
|
|
G
|
Tpcn1
|
two pore segment channel 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TPCN1 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr12:35,972,813...36,029,632
Ensembl chr12:35,972,846...36,029,626
|
|
G
|
Tpd52
|
tumor protein D52
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TPD52 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:94,642,514...94,723,442
Ensembl chr 2:92,735,620...92,816,622
|
|
G
|
Tpi1
|
triosephosphate isomerase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TPI1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:159,301,558...159,305,088
Ensembl chr 4:157,615,386...157,619,541
|
|
G
|
Tpm4
|
tropomyosin 4
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TPM4 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr16:17,718,442...17,732,483
Ensembl chr16:17,683,195...17,705,984
|
|
G
|
Tpp1
|
tripeptidyl peptidase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TPP1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:160,097,984...160,104,108
Ensembl chr 1:160,096,833...160,104,129
|
|
G
|
Tpp2
|
tripeptidyl peptidase 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TPP2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:46,046,712...46,128,157
Ensembl chr 9:46,046,632...46,128,157
|
|
G
|
Tpr
|
translocated promoter region, nuclear basket protein
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TPR mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr13:64,974,419...65,037,604
Ensembl chr13:62,424,312...62,487,496
|
|
G
|
Tprkb
|
Tp53rk binding protein
|
increases expression
|
ISO
|
Thimerosal results in increased expression of TPRKB mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:118,342,910...118,357,908
Ensembl chr 4:118,342,945...118,357,901
|
|
G
|
Traf5
|
TNF receptor-associated factor 5
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TRAF5 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr13:103,569,944...103,618,747
Ensembl chr13:103,572,314...103,618,709
|
|
G
|
Tram1
|
translocation associated membrane protein 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of TRAM1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:5,642,579...5,667,666
Ensembl chr 5:5,642,546...5,686,971
|
|
G
|
Trappc13
|
trafficking protein particle complex subunit 13
|
increases expression
|
ISO
|
Thimerosal results in increased expression of TRAPPC13 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:35,270,495...35,302,049
Ensembl chr 2:35,269,183...35,302,048
|
|
G
|
Trdmt1
|
tRNA aspartic acid methyltransferase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TRDMT1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr17:81,510,740...81,554,036
Ensembl chr17:76,610,543...76,645,439
|
|
G
|
Trerf1
|
transcriptional regulating factor 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TRERF1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:13,631,619...13,858,326
Ensembl chr 9:13,634,126...13,857,029
|
|
G
|
Trib3
|
tribbles pseudokinase 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TRIB3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:161,269,939...161,275,533
Ensembl chr 3:140,809,043...140,814,497
|
|
G
|
Trim13
|
tripartite motif-containing 13
|
increases expression
|
ISO
|
Thimerosal results in increased expression of TRIM13 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr15:35,733,548...35,772,676
Ensembl chr15:35,734,107...35,772,677
|
|
G
|
Trim14
|
tripartite motif-containing 14
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TRIM14 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:60,800,568...60,824,858
Ensembl chr 5:60,800,032...60,824,858
|
|
G
|
Trim23
|
tripartite motif-containing 23
|
increases expression
|
ISO
|
Thimerosal results in increased expression of TRIM23 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:35,302,405...35,335,746
Ensembl chr 2:35,302,409...35,335,743
|
|
G
|
Trim28
|
tripartite motif-containing 28
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TRIM28 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:73,652,441...73,659,388
Ensembl chr 1:73,652,709...73,659,380
|
|
G
|
Trim59
|
tripartite motif-containing 59
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TRIM59 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:153,269,210...153,281,185
Ensembl chr 2:153,268,584...153,281,031
|
|
G
|
Trim9
|
tripartite motif-containing 9
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TRIM9 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 6:88,756,824...88,856,588
Ensembl chr 6:88,757,303...88,856,542
|
|
G
|
Trmt10a
|
tRNA methyltransferase 10A
|
increases expression
|
ISO
|
Thimerosal results in increased expression of TRMT10A mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:229,342,853...229,357,573
Ensembl chr 2:226,669,832...226,684,151
|
|
G
|
Trpm3
|
transient receptor potential cation channel, subfamily M, member 3
|
increases expression
|
ISO
|
Thimerosal results in increased expression of TRPM3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:219,673,200...220,557,610
Ensembl chr 1:219,672,892...220,560,717
|
|
G
|
Tshb
|
thyroid stimulating hormone subunit beta
|
increases expression
|
ISO
|
Thimerosal results in increased expression of TSHB mRNA; Thimerosal results in increased expression of TSHB protein
|
CTD |
PMID:24675092 |
|
NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559
|
|
G
|
Tspan33
|
tetraspanin 33
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TSPAN33 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:58,305,378...58,330,013
Ensembl chr 4:58,305,437...58,328,940
|
|
G
|
Ttc39c
|
tetratricopeptide repeat domain 39C
|
multiple interactions
|
ISO
|
[NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TTC39C mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr18:3,768,802...3,887,932
Ensembl chr18:3,805,183...3,887,930
|
|
G
|
Ttyh2
|
tweety family member 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TTYH2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:99,709,063...99,753,449
Ensembl chr10:99,709,007...99,753,444
|
|
G
|
Tubb2a
|
tubulin, beta 2A class IIa
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TUBB2A mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714
|
|
G
|
Tubb4b
|
tubulin, beta 4B class IVb
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TUBB4B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:8,037,838...8,040,294
Ensembl chr 3:8,037,799...8,040,296
|
|
G
|
Tubgcp3
|
tubulin gamma complex component 3
|
increases expression
|
ISO
|
Thimerosal results in increased expression of TUBGCP3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr16:76,851,859...76,912,499
Ensembl chr16:76,851,810...76,912,499
|
|
G
|
Txn1
|
thioredoxin 1
|
multiple interactions decreases activity
|
ISO
|
[Thimerosal co-treated with Temozolomide] results in decreased activity of TXN protein Thimerosal results in decreased activity of TXN protein
|
CTD |
PMID:38325586 |
|
NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:72,711,933...72,724,629
|
|
G
|
Txndc9
|
thioredoxin domain containing 9
|
increases expression
|
ISO
|
Thimerosal results in increased expression of TXNDC9 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:40,211,818...40,221,953
Ensembl chr 9:40,211,412...40,384,279 Ensembl chr 9:40,211,412...40,384,279
|
|
G
|
Txnip
|
thioredoxin interacting protein
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of TXNIP mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:186,781,933...186,785,736
Ensembl chr 2:184,092,991...184,096,886
|
|
G
|
Txnrd1
|
thioredoxin reductase 1
|
multiple interactions decreases activity
|
ISO
|
[Thimerosal co-treated with Temozolomide] results in decreased activity of TXNRD1 protein Thimerosal results in decreased activity of TXNRD1 protein
|
CTD |
PMID:38325586 |
|
NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:20,830,045...20,907,863
|
|
G
|
Ube2l3
|
ubiquitin-conjugating enzyme E2L 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of UBE2L3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr11:97,300,584...97,343,084
Ensembl chr11:83,797,722...83,838,862
|
|
G
|
Ubn1
|
ubinuclein 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of UBN1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:10,496,576...10,532,010
Ensembl chr10:10,496,576...10,532,010
|
|
G
|
Ubn2
|
ubinuclein 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of UBN2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:67,165,278...67,251,562
Ensembl chr 4:67,166,346...67,230,491
|
|
G
|
Ubr1
|
ubiquitin protein ligase E3 component n-recognin 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of UBR1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:107,813,721...107,921,701
Ensembl chr 3:107,811,392...107,922,204
|
|
G
|
Ucp2
|
uncoupling protein 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of UCP2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:164,251,373...164,257,742
Ensembl chr 1:154,839,209...154,845,611
|
|
G
|
Ugcg
|
UDP-glucose ceramide glucosyltransferase
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of UGCG mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393
|
|
G
|
Uggt1
|
UDP-glucose glycoprotein glucosyltransferase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of UGGT1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:38,355,229...38,468,473
Ensembl chr 9:38,359,089...38,468,467
|
|
G
|
Ugt8
|
UDP glycosyltransferase 8
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of UGT8 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:216,938,884...217,007,167
Ensembl chr 2:214,264,483...214,332,660
|
|
G
|
Uhmk1
|
U2AF homology motif kinase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of UHMK1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr13:84,929,418...84,949,194
Ensembl chr13:82,401,187...82,416,292
|
|
G
|
Upf1
|
UPF1, RNA helicase and ATPase
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of UPF1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr16:19,076,594...19,097,365
Ensembl chr16:19,076,322...19,096,568
|
|
G
|
Upp1
|
uridine phosphorylase 1
|
increases expression
|
ISO
|
Thimerosal results in increased expression of UPP1 mRNA
|
CTD |
PMID:16870260 |
|
NCBI chr14:88,023,155...88,043,036
Ensembl chr14:83,809,960...83,829,462
|
|
G
|
Usp1
|
ubiquitin specific peptidase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of USP1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:113,587,564...113,598,934
Ensembl chr 5:113,587,564...113,598,932
|
|
G
|
Usp10
|
ubiquitin specific peptidase 10
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of USP10 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr19:47,972,858...48,014,900
Ensembl chr19:47,972,611...48,014,897
|
|
G
|
Usp16
|
ubiquitin specific peptidase 16
|
increases expression
|
ISO
|
Thimerosal results in increased expression of USP16 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr11:40,166,651...40,196,792
Ensembl chr11:26,681,414...26,710,539
|
|
G
|
Usp25
|
ubiquitin specific peptidase 25
|
affects expression
|
ISO
|
Thimerosal affects the expression of USP25 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr11:15,603,654...15,711,356
Ensembl chr11:15,603,881...15,711,348
|
|
G
|
Usp29
|
ubiquitin specific peptidase 29
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of USP29 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 1:66,874,216...67,097,731
Ensembl chr 1:66,874,017...67,097,686
|
|
G
|
Usp34
|
ubiquitin specific peptidase 34
|
affects expression
|
ISO
|
Thimerosal affects the expression of USP34 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr14:97,285,799...97,476,376
Ensembl chr14:97,286,018...97,476,376
|
|
G
|
Usp49
|
ubiquitin specific peptidase 49
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of USP49 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 9:13,305,640...13,366,132
Ensembl chr 9:13,308,178...13,366,132
|
|
G
|
Usp51
|
ubiquitin specific peptidase 51
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of USP51 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr X:18,374,940...18,381,472
Ensembl chr X:18,376,930...18,379,888
|
|
G
|
Vangl1
|
VANGL planar cell polarity protein 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of VANGL1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:189,586,681...189,637,609
Ensembl chr 2:189,589,229...189,637,619
|
|
G
|
Vapb
|
VAMP associated protein B and C
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of VAPB mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 3:182,954,247...182,997,018
Ensembl chr 3:162,535,905...162,573,763
|
|
G
|
Vasp
|
vasodilator-stimulated phosphoprotein
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of VASP mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:88,038,026...88,053,783
Ensembl chr 1:78,910,011...78,925,061
|
|
G
|
Vat1
|
vesicle amine transport 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of VAT1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:86,889,793...86,897,411
Ensembl chr10:86,389,545...86,397,224
|
|
G
|
Vcp
|
valosin-containing protein
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of VCP mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:62,005,984...62,025,387
Ensembl chr 5:57,210,168...57,229,571
|
|
G
|
Vegfa
|
vascular endothelial growth factor A
|
decreases expression multiple interactions
|
ISO
|
Thimerosal results in decreased expression of VEGFA mRNA [Thimerosal co-treated with Temozolomide] results in decreased expression of VEGFA protein
|
CTD |
PMID:27188386 PMID:38325586 |
|
NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641
|
|
G
|
Vegfb
|
vascular endothelial growth factor B
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of VEGFB mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:204,172,297...204,178,046
Ensembl chr 1:204,172,225...204,177,944
|
|
G
|
Vps37b
|
VPS37B subunit of ESCRT-I
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of VPS37B mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr12:32,560,047...32,589,015
Ensembl chr12:32,560,047...32,589,014
|
|
G
|
Vps53
|
VPS53 subunit of GARP complex
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of VPS53 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:60,919,820...61,038,674
Ensembl chr10:60,919,820...61,038,676
|
|
G
|
Vsig10l
|
V-set and immunoglobulin domain containing 10 like
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of VSIG10L mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 1:103,007,933...103,016,161
Ensembl chr 1:93,851,774...93,879,566
|
|
G
|
Wapl
|
WAPL cohesin release factor
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of WAPL mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr16:10,005,520...10,075,270
Ensembl chr16:10,004,941...10,073,510
|
|
G
|
Wasf2
|
WASP family member 2
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of WASF2 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 5:150,620,733...150,685,943
Ensembl chr 5:145,336,842...145,399,242
|
|
G
|
Wasl
|
WASP like actin nucleation promoting factor
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of WASL mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:54,049,081...54,097,653
Ensembl chr 4:53,083,536...53,132,022
|
|
G
|
Wdfy3
|
WD repeat and FYVE domain containing 3
|
increases expression
|
ISO
|
Thimerosal results in increased expression of WDFY3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr14:7,578,245...7,810,491
Ensembl chr14:7,606,628...7,810,482
|
|
G
|
Wdr49
|
WD repeat domain 49
|
increases expression
|
ISO
|
Thimerosal results in increased expression of WDR49 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 2:160,049,478...160,264,581
Ensembl chr 2:160,051,458...160,264,511
|
|
G
|
Wdr54
|
WD repeat domain 54
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of WDR54 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:115,654,968...115,677,979
Ensembl chr 4:115,654,968...115,661,562
|
|
G
|
Wdr59
|
WD repeat domain 59
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of WDR59 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr19:39,416,432...39,483,773
Ensembl chr19:39,416,429...39,483,698
|
|
G
|
Wdr86
|
WD repeat domain 86
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of WDR86 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 4:10,423,496...10,443,473
Ensembl chr 4:10,424,008...10,441,465
|
|
G
|
Wipf3
|
WAS/WASL interacting protein family, member 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of WIPF3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:83,550,075...83,629,929
Ensembl chr 4:83,550,468...83,629,386
|
|
G
|
Wnk1
|
WNK lysine deficient protein kinase 1
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of WNK1 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr 4:154,800,590...154,926,147
Ensembl chr 4:153,128,334...153,253,905
|
|
G
|
Wnt3
|
Wnt family member 3
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of WNT3 mRNA
|
CTD |
PMID:27188386 |
|
NCBI chr10:89,180,224...89,224,195
Ensembl chr10:88,680,248...88,724,099
|
|
G
|
Xiap
|
X-linked inhibitor of apoptosis
|
affects expression multiple interactions decreases expression
|
ISO
|
Thimerosal affects the expression of XIAP protein Glutathione inhibits the reaction [Thimerosal results in decreased expression of XIAP protein]
|
CTD |
PMID:12140745 PMID:16649253 |
|
NCBI chr X:125,756,107...125,803,979
Ensembl chr X:120,897,907...120,934,700
|
|
G
|
Zc3h12c
|
zinc finger CCCH type containing 12C
|
increases expression
|
ISO
|
Thimerosal results in increased expression of ZC3H12C mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 8:52,443,791...52,508,643
Ensembl chr 8:52,448,320...52,504,315
|
|
G
|
Zfp382
|
zinc finger protein 382
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ZFP382 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr 1:85,377,614...85,400,832
Ensembl chr 1:85,377,484...85,399,667
|
|
G
|
Zfp655
|
zinc finger protein 655
|
increases expression
|
ISO
|
Thimerosal results in increased expression of ZFP655 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr12:9,349,985...9,375,449
Ensembl chr12:9,357,639...9,374,569
|
|
G
|
Zfp958
|
zinc finger protein 958
|
decreases expression
|
ISO
|
Thimerosal results in decreased expression of ZFP958 mRNA
|
CTD |
PMID:24675092 |
|
NCBI chr12:3,953,442...3,975,328
Ensembl chr12:3,953,455...3,975,514 Ensembl chr12:3,953,455...3,975,514
|
|
|
G
|
Scd
|
stearoyl-CoA desaturase
|
decreases expression multiple interactions
|
ISO
|
Triarachidonin results in decreased expression of SCD1 mRNA Clofibrate inhibits the reaction [Triarachidonin results in decreased expression of SCD1 mRNA]
|
CTD |
PMID:8729090 PMID:8790349 |
|
NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:243,269,747...243,282,562
|
|