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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:erythrosin B
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Accession:CHEBI:61000 term browser browse the term
Definition:An organic sodium salt that is the disodium salt of 2-(2,4,5,7-tetraiodo-6-oxido-3-oxo-8a,10a-dihydroxanthen-9-yl)benzoic acid.
Synonyms:exact_synonym: disodium 2-(2,4,5,7-tetraiodo-6-oxido-3-oxo-8a,10a-dihydro-3H-xanthen-9-yl)benzoate
 related_synonym: 1427 Red;   1671 Red;   2',4',5',7'-Tetraiodofluoroescein disodium salt;   2,4,5,7-Tetraiodofluorescein disodium salt;   3',6-Dihydroxy-2',4',5',7'-tetraiodospiro(isobenzofuran-1(3H),9'(9H)xanthen)-one disodium salt;   Acid red 51;   Aizen Food Red 3;   Aizen erythrosine;   C.I. 45430;   Erythrosin;   Erythrosin B sodium salt;   Erythrosin BS;   Erythrosine;   Erythrosine sodium (close form);   FD&C Red No. 3;   Food Color Red 3;   Formula=C20H6I4Na2O5;   InChI=1S/C20H8I4O5.2Na/c21-11-5-9-13(7-3-1-2-4-8(7)20(27)28)10-6-12(22)17(26)15(24)19(10)29-18(9)14(23)16(11)25;;/h1-6,25H,(H,27,28);;/q;2*+1/p-2;   InChIKey=IINNWAYUJNWZRM-UHFFFAOYSA-L;   SMILES=[Na+].[Na+].[O-]C(=O)c1ccccc1-c1c2cc(I)c([O-])c(I)c2oc2c(I)c(=O)c(I)cc12
 xref: CAS:16423-68-0
 xref_mesh: MESH:D004923
 xref: PMID:15206583;   PMID:25308634;   Reaxys:3583865


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erythrosin B term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A decreases activity ISO Erythrosine results in decreased activity of ABCB1 protein CTD PMID:20041016 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Ccnd1 cyclin D1 increases expression ISO Erythrosine results in increased expression of CCND1 protein CTD PMID:8927716 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cdk2 cyclin dependent kinase 2 increases activity ISO Erythrosine results in increased activity of CDK2 protein CTD PMID:8927716 PMID:9168006 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity EXP Erythrosine results in decreased activity of CYP19A1 protein CTD PMID:18310892 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO Erythrosine results in increased expression of FOSL1 protein CTD PMID:20025956 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Erythrosine inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Hpgds hematopoietic prostaglandin D synthase decreases activity ISO Erythrosine results in decreased activity of HPGDS protein CTD PMID:25603235 NCBI chr 4:95,945,356...95,970,666
Ensembl chr 4:95,946,025...95,970,666
JBrowse link
G Iyd iodotyrosine deiodinase decreases activity ISO Erythrosine results in decreased activity of IYD protein CTD PMID:24012475 NCBI chr 1:40,086,513...40,100,966
Ensembl chr 1:40,086,470...40,101,840
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO Erythrosine results in increased expression of JUN protein CTD PMID:20025956 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Orm1 orosomucoid 1 increases expression ISO Erythrosine results in increased expression of ORM1 protein CTD PMID:20025956 NCBI chr 5:79,179,668...79,182,820
Ensembl chr 5:79,179,417...79,182,820
JBrowse link
G Phex phosphate regulating endopeptidase homolog, X-linked increases expression ISO Erythrosine results in increased expression of PHEX protein CTD PMID:20025956 NCBI chr  X:40,460,047...40,717,982
Ensembl chr  X:40,460,047...40,717,982
JBrowse link
G Tp53 tumor protein p53 increases activity ISO Erythrosine results in increased activity of TP53 protein CTD PMID:9168006 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Trh thyrotropin releasing hormone multiple interactions EXP Erythrosine promotes the reaction [TRH protein results in increased expression of TSHB protein] CTD PMID:2160137 NCBI chr 4:124,110,716...124,113,242
Ensembl chr 4:124,110,716...124,113,242
JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions EXP Erythrosine promotes the reaction [TRH protein results in increased expression of TSHB protein] CTD PMID:2160137 NCBI chr 2:205,207,799...205,215,199
Ensembl chr 2:205,207,799...205,212,681
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 decreases activity ISO Erythrosine results in decreased activity of UGT1A6 protein CTD PMID:20041016 NCBI chr 9:95,241,609...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 decreases activity ISO Erythrosine results in decreased activity of UGT2B7 protein CTD PMID:20041016 NCBI chr14:22,597,103...22,619,968 JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO Erythrosine results in increased expression of VEGFA protein CTD PMID:20025956 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19781
    role 19726
      application 19412
        dye 1312
          fluorescent dye 471
            erythrosin B 17
Path 2
Term Annotations click to browse term
  CHEBI ontology 19781
    subatomic particle 19779
      composite particle 19779
        hadron 19779
          baryon 19779
            nucleon 19779
              atomic nucleus 19779
                atom 19779
                  main group element atom 19669
                    p-block element atom 19669
                      carbon group element atom 19588
                        carbon atom 19578
                          organic molecular entity 19578
                            organic ion 8462
                              organic anion 3034
                                carboxylic acid anion 2394
                                  monocarboxylic acid anion 1499
                                    benzoates 1271
                                      erythrosin(2-) 17
                                        erythrosin B 17
paths to the root