CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: carnosic acid
Accession: CHEBI:65585
browse the term
Definition: An abietane diterpenoid that is abieta-8,11,13-triene substituted by hydroxy groups at positions 11 and 12 and a carboxy group at position 20. It is isolated from rosemary (Rosmarinus officinalis) and common sage (Salvia officinalis) and exhibits anti-angiogenic, antineoplastic, antioxidant and anti-HIV activity.
Synonyms: exact_synonym: 11,12-dihydroxyabieta-8,11,13-trien-20-oic acid
related_synonym: (4aR,10aS)-5,6-dihydroxy-1,1-dimethyl-7-(propan-2-yl)-1,3,4,9,10,10a-hexahydrophenanthrene-4a(2H)-carboxylic acid; 11,12-dihydroxy-13-isopropylpodocarpa-8,11,13-trien-17-oic acid; Formula=C20H28O4; InChI=1S/C20H28O4/c1-11(2)13-10-12-6-7-14-19(3,4)8-5-9-20(14,18(23)24)15(12)17(22)16(13)21/h10-11,14,21-22H,5-9H2,1-4H3,(H,23,24)/t14-,20+/m0/s1; InChIKey=QRYRORQUOLYVBU-VBKZILBWSA-N; SMILES=C1CC([C@]2([C@](C1)(C3=C(CC2)C=C(C(=C3O)O)C(C)C)C(=O)O)[H])(C)C; Salvin
xref: CAS:3650-09-7
xref_mesh: MESH:C018381
xref: MetaCyc:CPD-18103; PMID:11504768; PMID:17177234; PMID:22232247; PMID:22246562; PMID:22687582; PMID:22828666; PMID:26976595; PMID:27694001; PMID:27703160; PMID:27716981; PMID:27957651; PMID:28008719; PMID:28159594; PMID:28282784; PMID:28288941; PMID:28343998; PMID:28440400; PMID:28674855; PMID:28877257; PMID:28887507; PMID:28916593; PMID:28918123; PMID:29100552; PMID:8229021; Reaxys:2707918; Wikipedia:Carnosic_acid
cyclic_relationship: is_conjugate_acid_of CHEBI:138943
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A2M
alpha-2-macroglobulin
decreases expression
ISO
salvin results in decreased expression of A2M protein
CTD
PMID:35926579
NCBI chr12:9,067,708...9,116,229
Ensembl chr12:9,067,664...9,116,229
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AACS
acetoacetyl-CoA synthetase
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of AACS mRNA]
CTD
PMID:35202923
NCBI chr12:125,065,435...125,143,316
Ensembl chr12:125,065,434...125,143,333
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ABAT
4-aminobutyrate aminotransferase
increases expression
ISO
salvin results in increased expression of ABAT protein
CTD
PMID:35926579
NCBI chr16:8,674,617...8,784,570
Ensembl chr16:8,674,596...8,784,575
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ABCA6
ATP binding cassette subfamily A member 6
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of ABCA6 mRNA]
CTD
PMID:35202923
NCBI chr17:69,078,702...69,141,895
Ensembl chr17:69,078,702...69,141,895
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ABHD11
abhydrolase domain containing 11
increases expression
ISO
salvin results in increased expression of ABHD11 protein
CTD
PMID:35926579
NCBI chr 7:73,736,094...73,738,802
Ensembl chr 7:73,736,094...73,738,852
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ABI1
abl interactor 1
increases expression
ISO
salvin results in increased expression of ABI1 protein
CTD
PMID:35926579
NCBI chr10:26,746,596...26,860,958
Ensembl chr10:26,746,593...26,861,087
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ACLY
ATP citrate lyase
increases expression
ISO
salvin results in increased expression of ACLY protein
CTD
PMID:35926579
NCBI chr17:41,866,917...41,930,545
Ensembl chr17:41,866,917...41,930,542
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ACSS2
acyl-CoA synthetase short chain family member 2
increases expression
ISO
salvin results in increased expression of ACSS2 protein
CTD
PMID:35926579
NCBI chr20:34,874,989...34,927,959
Ensembl chr20:34,872,146...34,927,962
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ACTN1
actinin alpha 1
increases expression
ISO
salvin results in increased expression of ACTN1 protein
CTD
PMID:35926579
NCBI chr14:68,874,128...68,979,302
Ensembl chr14:68,874,128...68,979,440
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ADCY9
adenylate cyclase 9
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of ADCY9 mRNA]
CTD
PMID:35202923
NCBI chr16:3,953,387...4,116,442
Ensembl chr16:3,953,387...4,116,442
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ADGRE1
adhesion G protein-coupled receptor E1
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of ADGRE1 mRNA]
CTD
PMID:35202923
NCBI chr19:6,887,579...6,940,450
Ensembl chr19:6,887,566...6,940,459
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ADGRE4P
adhesion G protein-coupled receptor E4, pseudogene
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of ADGRE4 mRNA]
CTD
PMID:35202923
NCBI chr19:6,950,758...6,997,851
Ensembl chr19:6,954,659...6,990,798
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ADH1C
alcohol dehydrogenase 1C (class I), gamma polypeptide
increases expression
ISO
salvin results in increased expression of ADH1 protein
CTD
PMID:35926579
NCBI chr 4:99,336,497...99,352,746
Ensembl chr 4:99,336,497...99,352,746
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AEBP1
AE binding protein 1
decreases expression
ISO
salvin results in decreased expression of AEBP1 protein
CTD
PMID:35926579
NCBI chr 7:44,104,345...44,114,560
Ensembl chr 7:44,104,345...44,114,562
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AGPS
alkylglycerone phosphate synthase
decreases expression
ISO
salvin results in decreased expression of AGPS protein
CTD
PMID:35926579
NCBI chr 2:177,392,773...177,543,834
Ensembl chr 2:177,392,746...177,567,024
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AHSG
alpha 2-HS glycoprotein
decreases expression
ISO
salvin results in decreased expression of AHSG protein
CTD
PMID:35926579
NCBI chr 3:186,613,060...186,621,318
Ensembl chr 3:186,613,060...186,621,318
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AKT1
AKT serine/threonine kinase 1
increases phosphorylation decreases phosphorylation
EXP
salvin results in increased phosphorylation of AKT1 protein salvin results in decreased phosphorylation of AKT1 protein
CTD
PMID:25178877 PMID:25271104
NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759
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ALB
albumin
decreases expression
ISO
salvin results in decreased expression of ALB protein
CTD
PMID:35926579
NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
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ALDH1A3
aldehyde dehydrogenase 1 family member A3
decreases expression
ISO
salvin results in decreased expression of ALDH1A3 protein
CTD
PMID:35926579
NCBI chr15:100,879,831...100,916,626
Ensembl chr15:100,877,714...100,916,626
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APAF1
apoptotic peptidase activating factor 1
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in increased expression of APAF1 protein]
CTD
PMID:29854073
NCBI chr12:98,645,290...98,735,433
Ensembl chr12:98,645,149...98,735,433
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APOA1
apolipoprotein A1
decreases expression
ISO
salvin results in decreased expression of APOA1 protein
CTD
PMID:35926579
NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622
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APOA4
apolipoprotein A4
decreases expression
ISO
salvin results in decreased expression of APOA4 protein
CTD
PMID:35926579
NCBI chr11:116,820,700...116,823,304
Ensembl chr11:116,820,700...116,823,304
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APOE
apolipoprotein E
decreases expression
ISO
salvin results in decreased expression of APOE protein
CTD
PMID:35926579
NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
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APOH
apolipoprotein H
decreases expression
ISO
salvin results in decreased expression of APOH protein
CTD
PMID:35926579
NCBI chr17:66,212,033...66,229,415
Ensembl chr17:66,212,033...66,256,525
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ASNS
asparagine synthetase (glutamine-hydrolyzing)
decreases expression
ISO
salvin results in decreased expression of ASNS protein
CTD
PMID:35926579
NCBI chr 7:97,851,677...97,928,441
Ensembl chr 7:97,851,677...97,872,542
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ASPA
aspartoacylase
decreases expression
ISO
salvin results in decreased expression of ASPA protein
CTD
PMID:35926579
NCBI chr17:3,474,110...3,503,405
Ensembl chr17:3,472,374...3,503,405
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ASPN
asporin
increases expression
ISO
salvin results in increased expression of ASPN protein
CTD
PMID:35926579
NCBI chr 9:92,456,205...92,482,506
Ensembl chr 9:92,456,205...92,482,506
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ATP12A
ATPase H+/K+ transporting non-gastric alpha2 subunit
increases expression
ISO
salvin results in increased expression of ATP12A protein
CTD
PMID:35926579
NCBI chr13:24,680,408...24,712,472
Ensembl chr13:24,680,408...24,712,472
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B2M
beta-2-microglobulin
increases expression
ISO
salvin results in increased expression of B2M protein
CTD
PMID:35926579
NCBI chr15:44,711,517...44,718,145
Ensembl chr15:44,711,358...44,718,851
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BAD
BCL2 associated agonist of cell death
multiple interactions decreases phosphorylation increases expression
EXP
salvin promotes the reaction [arsenic trioxide results in decreased phosphorylation of BAD protein] salvin results in decreased phosphorylation of BAD protein salvin results in increased expression of BAD protein
CTD
PMID:23239002 PMID:28918123
NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704
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BASP1
brain abundant membrane attached signal protein 1
decreases expression
ISO
salvin results in decreased expression of BASP1 protein
CTD
PMID:35926579
NCBI chr 5:17,216,823...17,276,834
Ensembl chr 5:17,065,598...17,276,843
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BAX
BCL2 associated X, apoptosis regulator
multiple interactions increases expression
EXP ISO
salvin inhibits the reaction [Paraquat results in increased expression of BAX protein]; salvin inhibits the reaction [Pyruvaldehyde results in increased expression of BAX protein] salvin results in increased expression of BAX protein salvin inhibits the reaction [sodium arsenite results in increased expression of BAX protein]
CTD
PMID:26577515 PMID:26686574 PMID:28918123 PMID:29854073
NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
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BCAS2
BCAS2 pre-mRNA processing factor
decreases expression
ISO
salvin results in decreased expression of BCAS2 protein
CTD
PMID:35926579
NCBI chr 1:114,567,557...114,581,615
Ensembl chr 1:114,567,557...114,581,629
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BCL2
BCL2 apoptosis regulator
multiple interactions decreases expression
ISO EXP
salvin inhibits the reaction [Oxidopamine results in decreased expression of BCL2 protein] Acetylcysteine inhibits the reaction [salvin results in decreased expression of BCL2 protein]; PINK1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in decreased expression of BCL2 protein]]; salvin inhibits the reaction [Oxidopamine results in decreased expression of BCL2 protein]; salvin inhibits the reaction [Paraquat results in decreased expression of BCL2 protein]; salvin inhibits the reaction [Pyruvaldehyde results in decreased expression of BCL2 protein] salvin inhibits the reaction [sodium arsenite results in decreased expression of BCL2 protein]
CTD
PMID:25446857 PMID:26577515 PMID:26686574 PMID:28918123 PMID:29854073 PMID:30707903 More...
NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
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BCL2L2
BCL2 like 2
multiple interactions
EXP
salvin inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased expression of BCL2L2 protein]
CTD
PMID:24557422
NCBI chr14:23,306,833...23,311,751
Ensembl chr14:23,298,790...23,311,751
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BMP5
bone morphogenetic protein 5
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of BMP5 mRNA]
CTD
PMID:35202923
NCBI chr 6:55,753,653...55,875,590
Ensembl chr 6:55,753,653...55,875,590
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BZW2
basic leucine zipper and W2 domains 2
decreases expression
ISO
salvin results in decreased expression of BZW2 protein
CTD
PMID:35926579
NCBI chr 7:16,646,181...16,706,517
Ensembl chr 7:16,646,131...16,706,523
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C3
complement C3
decreases expression
ISO
salvin results in decreased expression of C3 protein
CTD
PMID:35926579
NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
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C4B
complement C4B (Chido/Rodgers blood group)
decreases expression
ISO
salvin results in decreased expression of C4B protein
CTD
PMID:35926579
NCBI chr 6:32,014,795...32,035,418
Ensembl chr 6:32,014,795...32,035,418
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CA2
carbonic anhydrase 2
increases expression
ISO
salvin results in increased expression of CA2 protein
CTD
PMID:35926579
NCBI chr 8:85,464,007...85,481,493
Ensembl chr 8:85,463,968...85,481,493
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CAMP
cathelicidin antimicrobial peptide
decreases expression
ISO
salvin results in decreased expression of CAMP protein
CTD
PMID:35926579
NCBI chr 3:48,223,495...48,225,485
Ensembl chr 3:48,223,347...48,225,491
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CASP14
caspase 14
increases expression
ISO
salvin results in increased expression of CASP14 protein
CTD
PMID:35926579
NCBI chr19:15,049,480...15,058,293
Ensembl chr19:15,049,480...15,058,293
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CASP3
caspase 3
multiple interactions increases cleavage
EXP ISO
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin inhibits the reaction [Paraquat results in increased activity of CASP3 protein]]; Acetylcysteine inhibits the reaction [salvin results in increased cleavage of CASP3 protein]; GSTP1 mutant form inhibits the reaction [salvin inhibits the reaction [Oxidopamine results in increased cleavage of CASP3 protein]]; OPA1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in increased cleavage of CASP3 protein]]; PINK1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in increased cleavage of CASP3 protein]]; salvin inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased cleavage of CASP3 protein]; salvin inhibits the reaction [Acrylamide results in increased expression of CASP3 mRNA]; salvin inhibits the reaction [Oxidopamine results in increased cleavage of CASP3 protein]; salvin inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; salvin inhibits the reaction [Pyruvaldehyde results in increased expression of CASP3 protein] salvin inhibits the reaction [sodium arsenite results in increased cleavage of CASP3 protein]
CTD
PMID:24557422 PMID:25271104 PMID:25446857 PMID:26577515 PMID:26686574 PMID:28159594 PMID:28918123 PMID:29854073 PMID:30707903 PMID:31705926 More...
NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
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CASP6
caspase 6
decreases expression
ISO
salvin results in decreased expression of CASP6 protein
CTD
PMID:35926579
NCBI chr 4:109,664,388...109,709,767
Ensembl chr 4:109,688,622...109,703,583
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CASP8
caspase 8
multiple interactions increases cleavage
EXP ISO
Acetylcysteine inhibits the reaction [salvin results in increased cleavage of CASP8 protein] salvin inhibits the reaction [sodium arsenite results in increased cleavage of CASP8 protein]
CTD
PMID:28918123 PMID:29854073
NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836
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CASP9
caspase 9
increases activity multiple interactions increases cleavage
EXP ISO
salvin results in increased activity of CASP9 protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin inhibits the reaction [Pyruvaldehyde results in increased expression of CASP9 protein]]; Acetylcysteine inhibits the reaction [salvin results in increased cleavage of CASP9 protein]; salvin inhibits the reaction [Acrylamide results in increased expression of CASP9 mRNA]; salvin inhibits the reaction [Paraquat results in increased activity of CASP9 protein]; salvin inhibits the reaction [Pyruvaldehyde results in increased expression of CASP9 protein]; salvin promotes the reaction [arsenic trioxide results in increased activity of CASP9 protein] salvin inhibits the reaction [sodium arsenite results in increased cleavage of CASP9 protein]
CTD
PMID:23239002 PMID:26577515 PMID:26686574 PMID:28159594 PMID:28918123 PMID:29854073 More...
NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
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CAT
catalase
multiple interactions
EXP ISO
salvin inhibits the reaction [Acrylamide results in decreased activity of CAT protein]; salvin inhibits the reaction [Acrylamide results in decreased expression of CAT mRNA] salvin inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]
CTD
PMID:28159594 PMID:29854073
NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
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CD14
CD14 molecule
multiple interactions
EXP
[salvin co-treated with Tretinoin] results in increased expression of CD14 protein; salvin promotes the reaction [Calcitriol results in increased expression of CD14 protein]
CTD
PMID:11504768
NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700
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CD177
CD177 molecule
decreases expression
ISO
salvin results in decreased expression of CD177 protein
CTD
PMID:35926579
NCBI chr19:43,353,686...43,366,081
Ensembl chr19:43,353,686...43,363,172
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CDKN1B
cyclin dependent kinase inhibitor 1B
increases expression multiple interactions
EXP
salvin results in increased expression of CDKN1B protein salvin promotes the reaction [arsenic trioxide results in increased expression of CDKN1B protein]
CTD
PMID:23239002
NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369
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CELA1
chymotrypsin like elastase 1
decreases expression
ISO
salvin results in decreased expression of CELA1 protein
CTD
PMID:35926579
NCBI chr12:51,328,442...51,346,679
Ensembl chr12:51,328,442...51,346,679
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CELA3B
chymotrypsin like elastase 3B
decreases expression
ISO
salvin results in decreased expression of CELA3B protein
CTD
PMID:35926579
NCBI chr 1:21,977,022...21,998,642
Ensembl chr 1:21,977,022...21,998,642
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CHP2
calcineurin like EF-hand protein 2
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of CHP2 mRNA]
CTD
PMID:35202923
NCBI chr16:23,755,026...23,758,935
Ensembl chr16:23,755,026...23,758,935
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CKMT1B
creatine kinase, mitochondrial 1B
increases expression
ISO
salvin results in increased expression of CKMT1 protein
CTD
PMID:35926579
NCBI chr15:43,592,857...43,599,406
Ensembl chr15:43,593,054...43,604,901 Ensembl chr15:43,593,054...43,604,901
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CLCA1
chloride channel accessory 1
increases expression
ISO
salvin results in increased expression of CLCA1 protein
CTD
PMID:35926579
NCBI chr 1:86,468,927...86,500,259
Ensembl chr 1:86,468,368...86,500,259
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CLCA4
chloride channel accessory 4
decreases expression
ISO
salvin results in decreased expression of CLCA4A protein
CTD
PMID:35926579
NCBI chr 1:86,547,078...86,580,754
Ensembl chr 1:86,547,078...86,580,754
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CLEC14A
C-type lectin domain containing 14A
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of CLEC14A mRNA]
CTD
PMID:35202923
NCBI chr14:38,254,000...38,256,093
Ensembl chr14:38,254,000...38,256,093
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CLIC5
chloride intracellular channel 5
increases expression
ISO
salvin results in increased expression of CLIC5 protein
CTD
PMID:35926579
NCBI chr 6:45,880,827...46,129,819
Ensembl chr 6:45,880,827...46,080,348
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CLNS1A
chloride nucleotide-sensitive channel 1A
increases expression
ISO
salvin results in increased expression of CLNS1A protein
CTD
PMID:35926579
NCBI chr11:77,614,530...77,637,794
Ensembl chr11:77,514,936...77,637,794
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CLU
clusterin
decreases expression
ISO
salvin results in decreased expression of CLU protein
CTD
PMID:35926579
NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700
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COL18A1
collagen type XVIII alpha 1 chain
decreases expression
ISO
salvin results in decreased expression of COL18A1 protein
CTD
PMID:35926579
NCBI chr21:45,405,165...45,513,720
Ensembl chr21:45,405,165...45,513,720
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COL6A3
collagen type VI alpha 3 chain
decreases expression
ISO
salvin results in decreased expression of COL6A3 protein
CTD
PMID:35926579
NCBI chr 2:237,324,018...237,414,164
Ensembl chr 2:237,324,003...237,414,328
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COX6A1
cytochrome c oxidase subunit 6A1
increases expression
ISO
salvin results in increased expression of COX6A1 protein
CTD
PMID:35926579
NCBI chr12:120,438,113...120,440,730
Ensembl chr12:120,438,090...120,440,737
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CP
ceruloplasmin
decreases expression
ISO
salvin results in decreased expression of CP protein
CTD
PMID:35926579
NCBI chr 3:149,162,414...149,221,829
Ensembl chr 3:149,162,410...149,221,829
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CPB1
carboxypeptidase B1
decreases expression
ISO
salvin results in decreased expression of CPB1 protein
CTD
PMID:35926579
NCBI chr 3:148,827,811...148,860,187
Ensembl chr 3:148,791,102...148,860,187
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CPOX
coproporphyrinogen oxidase
increases expression
ISO
salvin results in increased expression of CPOX protein
CTD
PMID:35926579
NCBI chr 3:98,570,488...98,593,611
Ensembl chr 3:98,579,446...98,593,648
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CPSF7
cleavage and polyadenylation specific factor 7
decreases expression
ISO
salvin results in decreased expression of CPSF7 protein
CTD
PMID:35926579
NCBI chr11:61,402,729...61,429,975
Ensembl chr11:61,402,641...61,430,031
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CRNKL1
crooked neck pre-mRNA splicing factor 1
decreases expression
ISO
salvin results in decreased expression of CRNKL1 protein
CTD
PMID:35926579
NCBI chr20:20,034,368...20,056,046
Ensembl chr20:20,034,368...20,056,046
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CTRB2
chymotrypsinogen B2
decreases expression
ISO
salvin results in decreased expression of CTRB1 protein
CTD
PMID:35926579
NCBI chr16:75,204,103...75,207,161
Ensembl chr16:75,204,103...75,207,161
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CYBB
cytochrome b-245 beta chain
decreases expression
ISO
salvin results in decreased expression of CYBB protein
CTD
PMID:35926579
NCBI chr X:37,780,059...37,813,461
Ensembl chr X:37,780,018...37,813,461
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CYP20A1
cytochrome P450 family 20 subfamily A member 1
decreases expression
ISO
salvin results in decreased expression of CYP20A1 protein
CTD
PMID:35926579
NCBI chr 2:203,239,018...203,306,026
Ensembl chr 2:203,238,977...203,306,026
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CYP2B6
cytochrome P450 family 2 subfamily B member 6
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of CYP2B10 mRNA]
CTD
PMID:35202923
NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398
G
CYP2C9
cytochrome P450 family 2 subfamily C member 9
decreases expression
ISO
salvin results in decreased expression of CYP2C65 protein
CTD
PMID:35926579
NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091
G
CYP51A1
cytochrome P450 family 51 subfamily A member 1
decreases expression
ISO
salvin results in decreased expression of CYP51A1 protein
CTD
PMID:35926579
NCBI chr 7:92,112,153...92,134,803
Ensembl chr 7:92,084,987...92,134,803
G
CYP7A1
cytochrome P450 family 7 subfamily A member 1
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of CYP7A1 mRNA]
CTD
PMID:35202923
NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163
G
DMBT1
deleted in malignant brain tumors 1
decreases expression
ISO
salvin results in decreased expression of DMBT1 protein
CTD
PMID:35926579
NCBI chr10:122,560,754...122,643,736
Ensembl chr10:122,560,665...122,643,736
G
DNAJC10
DnaJ heat shock protein family (Hsp40) member C10
decreases expression
ISO
salvin results in decreased expression of DNAJC10 protein
CTD
PMID:35926579
NCBI chr 2:182,716,257...182,794,464
Ensembl chr 2:182,716,255...182,794,464
G
DOP1B
DOP1 leucine zipper like protein B
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of DOP1B mRNA]
CTD
PMID:35202923
NCBI chr21:36,156,824...36,294,274
Ensembl chr21:36,156,782...36,294,274
G
DPEP1
dipeptidase 1
decreases expression
ISO
salvin results in decreased expression of DPEP1 protein
CTD
PMID:35926579
NCBI chr16:89,613,308...89,641,540
Ensembl chr16:89,613,308...89,638,456
G
EHHADH
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in increased expression of EHHADH mRNA]
CTD
PMID:35202923
NCBI chr 3:185,190,624...185,254,049
Ensembl chr 3:185,190,624...185,281,990
G
ELANE
elastase, neutrophil expressed
decreases expression
ISO
salvin results in decreased expression of ELANE protein
CTD
PMID:35926579
NCBI chr19:852,303...856,243
Ensembl chr19:851,014...856,247
G
ENO3
enolase 3
increases expression
ISO
salvin results in increased expression of ENO3 protein
CTD
PMID:35926579
NCBI chr17:4,948,710...4,957,129
Ensembl chr17:4,948,092...4,957,131
G
FABP1
fatty acid binding protein 1
decreases expression
ISO
salvin results in decreased expression of FABP1 protein
CTD
PMID:35926579
NCBI chr 2:88,122,982...88,128,062
Ensembl chr 2:88,122,982...88,128,062
G
FABP5
fatty acid binding protein 5
decreases expression
ISO
salvin results in decreased expression of FABP5 protein
CTD
PMID:35926579
NCBI chr 8:81,280,536...81,284,775
Ensembl chr 8:81,280,536...81,284,777
G
FAS
Fas cell surface death receptor
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in increased expression of FAS protein]
CTD
PMID:29854073
NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605
G
FBLN2
fibulin 2
decreases expression
ISO
salvin results in decreased expression of FBLN2 protein
CTD
PMID:35926579
NCBI chr 3:13,549,125...13,638,404
Ensembl chr 3:13,549,125...13,638,422
G
FEN1
flap structure-specific endonuclease 1
decreases expression
ISO
salvin results in decreased expression of FEN1 protein
CTD
PMID:35926579
NCBI chr11:61,792,911...61,797,238
Ensembl chr11:61,792,911...61,797,238
G
FGA
fibrinogen alpha chain
decreases expression
ISO
salvin results in decreased expression of FGA protein
CTD
PMID:35926579
NCBI chr 4:154,583,126...154,590,742
Ensembl chr 4:154,583,126...154,590,742
G
FGB
fibrinogen beta chain
decreases expression
ISO
salvin results in decreased expression of FGB protein
CTD
PMID:35926579
NCBI chr 4:154,562,980...154,572,807
Ensembl chr 4:154,563,011...154,572,807
G
FGF21
fibroblast growth factor 21
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in increased expression of FGF21 mRNA]
CTD
PMID:35202923
NCBI chr19:48,755,524...48,758,330
Ensembl chr19:48,755,524...48,758,333
G
FGG
fibrinogen gamma chain
decreases expression
ISO
salvin results in decreased expression of FGG protein
CTD
PMID:35926579
NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967
G
FIS1
fission, mitochondrial 1
multiple interactions
EXP
salvin inhibits the reaction [Oxidopamine results in increased expression of FIS1 protein]
CTD
PMID:31705926
NCBI chr 7:101,239,472...101,245,081
Ensembl chr 7:101,239,458...101,252,316
G
FMO2
flavin containing dimethylaniline monoxygenase 2
increases expression
ISO
salvin results in increased expression of FMO2 protein
CTD
PMID:35926579
NCBI chr 1:171,185,208...171,212,686
Ensembl chr 1:171,185,249...171,212,686
G
FSCN1
fascin actin-bundling protein 1
decreases expression
ISO
salvin results in decreased expression of FSCN1 protein
CTD
PMID:35926579
NCBI chr 7:5,592,816...5,606,655
Ensembl chr 7:5,592,816...5,606,655
G
GALNT12
polypeptide N-acetylgalactosaminyltransferase 12
decreases expression
ISO
salvin results in decreased expression of GALNT12 protein
CTD
PMID:35926579
NCBI chr 9:98,807,670...98,850,081
Ensembl chr 9:98,807,670...98,850,081
G
GALNT3
polypeptide N-acetylgalactosaminyltransferase 3
decreases expression
ISO
salvin results in decreased expression of GALNT3 protein
CTD
PMID:35926579
NCBI chr 2:165,747,588...165,794,692
Ensembl chr 2:165,747,588...165,846,201
G
GARRE1
granule associated Rac and RHOG effector 1
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of GARRE1 mRNA]
CTD
PMID:35202923
NCBI chr19:34,254,554...34,355,566
Ensembl chr19:34,254,552...34,355,566
G
GC
GC vitamin D binding protein
decreases expression
ISO
salvin results in decreased expression of GC protein
CTD
PMID:35926579
NCBI chr 4:71,741,693...71,805,520
Ensembl chr 4:71,741,696...71,804,041
G
GCLC
glutamate-cysteine ligase catalytic subunit
increases expression multiple interactions
ISO EXP
salvin results in increased expression of GCLC mRNA salvin inhibits the reaction [Oxidopamine results in decreased expression of GCLC protein] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin results in increased expression of GCLC protein]; NFE2L2 mutant form inhibits the reaction [salvin results in increased expression of GCLC protein]; NFE2L2 protein promotes the reaction [salvin results in increased expression of GCLC protein]; salvin inhibits the reaction [Oxidopamine results in decreased expression of GCLC protein]
CTD
PMID:18329808 PMID:25446857 PMID:26577515 PMID:26686574
NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970
G
GCLM
glutamate-cysteine ligase modifier subunit
multiple interactions increases expression
ISO EXP
salvin inhibits the reaction [Oxidopamine results in decreased expression of GCLM protein] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin results in increased expression of GCLM protein]; NFE2L2 mutant form inhibits the reaction [salvin results in increased expression of GCLM protein]; NFE2L2 protein promotes the reaction [salvin results in increased expression of GCLM protein]; salvin inhibits the reaction [Acrylamide results in decreased expression of GCLM mRNA]; salvin inhibits the reaction [Oxidopamine results in decreased expression of GCLM protein]
CTD
PMID:25446857 PMID:26577515 PMID:26686574 PMID:28159594
NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456
G
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
decreases expression
ISO
salvin results in decreased expression of GCNT3 protein
CTD
PMID:35926579
NCBI chr15:59,549,039...59,622,723
Ensembl chr15:59,594,875...59,640,239
G
GFER
growth factor, augmenter of liver regeneration
increases expression
ISO
salvin results in increased expression of GFER protein
CTD
PMID:35926579
NCBI chr16:1,984,193...1,987,749
Ensembl chr16:1,984,193...1,987,749
G
GGH
gamma-glutamyl hydrolase
increases expression
ISO
salvin results in increased expression of GGH protein
CTD
PMID:35926579
NCBI chr 8:63,015,079...63,038,806
Ensembl chr 8:63,014,881...63,039,407
G
GLOD5
glyoxalase domain containing 5
increases expression
ISO
salvin results in increased expression of GLOD5 protein
CTD
PMID:35926579
NCBI chr X:48,761,747...48,773,648
Ensembl chr X:48,761,747...48,773,648
G
GNL3
G protein nucleolar 3
decreases expression
ISO
salvin results in decreased expression of GNL3 protein
CTD
PMID:35926579
NCBI chr 3:52,685,920...52,694,497
Ensembl chr 3:52,681,156...52,694,497
G
GPT
glutamic--pyruvic transaminase
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in increased expression of GPT protein]
CTD
PMID:29854073 PMID:35202923
NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174
G
GPX1
glutathione peroxidase 1
multiple interactions
EXP
salvin inhibits the reaction [Acrylamide results in decreased expression of GPX1 mRNA]
CTD
PMID:28159594
NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605
G
GRN
granulin precursor
decreases expression
ISO
salvin results in decreased expression of GRN protein
CTD
PMID:35926579
NCBI chr17:44,345,302...44,353,106
Ensembl chr17:44,345,246...44,353,106
G
GSDMC
gasdermin C
increases expression
ISO
salvin results in increased expression of GSDMC2 protein
CTD
PMID:35926579
NCBI chr 8:129,705,435...129,786,624
Ensembl chr 8:129,748,196...129,786,624
G
GSDME
gasdermin E
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in increased expression of GSDME mRNA]
CTD
PMID:35202923
NCBI chr 7:24,698,355...24,795,539
Ensembl chr 7:24,698,355...24,757,940
G
GSR
glutathione-disulfide reductase
multiple interactions increases expression
ISO EXP
salvin inhibits the reaction [Oxidopamine results in decreased expression of GSR protein] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin results in increased expression of GSR protein]; NFE2L2 mutant form inhibits the reaction [salvin results in increased expression of GSR protein]; NFE2L2 protein promotes the reaction [salvin results in increased expression of GSR protein]; salvin inhibits the reaction [Oxidopamine results in decreased expression of GSR protein] salvin inhibits the reaction [sodium arsenite results in decreased activity of GSR protein]
CTD
PMID:25446857 PMID:26577515 PMID:26686574 PMID:29854073
NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
G
GSTP1
glutathione S-transferase pi 1
multiple interactions increases expression
ISO EXP
salvin inhibits the reaction [Oxidopamine results in decreased expression of GSTP1 protein] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin inhibits the reaction [Oxidopamine results in decreased expression of GSTP1 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin results in increased expression of GSTP1 protein]; GSTP1 mutant form inhibits the reaction [salvin inhibits the reaction [Oxidopamine results in decreased expression of GSTP1 protein]]; GSTP1 mutant form inhibits the reaction [salvin inhibits the reaction [Oxidopamine results in increased cleavage of CASP3 protein]]; NFE2L2 mutant form inhibits the reaction [salvin results in increased expression of GSTP1 protein]; salvin inhibits the reaction [Oxidopamine results in decreased expression of GSTP1 protein]; salvin results in increased expression of and results in increased activity of GSTP1 protein
CTD
PMID:25271104 PMID:26577515
NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
G
GTF2F1
general transcription factor IIF subunit 1
decreases expression
ISO
salvin results in decreased expression of GTF2F1 protein
CTD
PMID:35926579
NCBI chr19:6,379,572...6,393,164
Ensembl chr19:6,379,572...6,393,981
G
HMGCS2
3-hydroxy-3-methylglutaryl-CoA synthase 2
decreases expression
ISO
salvin results in decreased expression of HMGCS2 protein
CTD
PMID:35926579
NCBI chr 1:119,747,996...119,768,932
Ensembl chr 1:119,748,002...119,768,905
G
HMOX1
heme oxygenase 1
increases expression multiple interactions
ISO EXP
salvin results in increased expression of HMOX1 mRNA; salvin results in increased expression of HMOX1 protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin results in increased expression of HMOX1 protein]; NFE2L2 protein promotes the reaction [salvin results in increased expression of HMOX1 protein]
CTD
PMID:18329808 PMID:23942037 PMID:26686574
NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
G
HNRNPA3
heterogeneous nuclear ribonucleoprotein A3
decreases expression
ISO
salvin results in decreased expression of HNRNPA3 protein
CTD
PMID:35926579
NCBI chr 2:177,212,794...177,223,959
Ensembl chr 2:177,212,694...177,223,959
G
HP
haptoglobin
decreases expression
ISO
salvin results in decreased expression of HP protein
CTD
PMID:35926579
NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055
G
HPX
hemopexin
decreases expression
ISO
salvin results in decreased expression of HPX protein
CTD
PMID:35926579
NCBI chr11:6,431,049...6,440,987
Ensembl chr11:6,431,049...6,442,617
G
HSD17B6
hydroxysteroid 17-beta dehydrogenase 6
decreases expression
ISO
salvin results in decreased expression of HSD17B6 protein
CTD
PMID:35926579
NCBI chr12:56,763,324...56,787,790
Ensembl chr12:56,752,161...56,787,790
G
ID3
inhibitor of DNA binding 3
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in increased expression of ID3 mRNA]
CTD
PMID:35202923
NCBI chr 1:23,557,926...23,559,501
Ensembl chr 1:23,557,926...23,559,501
G
IFNG
interferon gamma
multiple interactions
ISO
salvin inhibits the reaction [IFNG protein results in increased abundance of Nitrites]
CTD
PMID:23942037
NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
G
IGFBP7
insulin like growth factor binding protein 7
decreases expression
ISO
salvin results in decreased expression of IGFBP7 protein
CTD
PMID:35926579
NCBI chr 4:57,030,773...57,110,385
Ensembl chr 4:57,030,773...57,110,385
G
IGHM
immunoglobulin heavy constant mu
decreases expression
ISO
salvin results in decreased expression of IGHM protein
CTD
PMID:35926579
NCBI chr14:105,851,966...105,856,217
Ensembl chr14:105,851,705...105,856,218
G
IGKV2D-30
immunoglobulin kappa variable 2D-30
decreases expression
ISO
salvin results in decreased expression of IGKV1-133 protein
CTD
PMID:35926579
NCBI chr 2:89,936,894...89,937,679
Ensembl chr 2:89,936,859...89,937,679
G
IKBKG
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
increases ubiquitination multiple interactions
EXP
salvin results in increased ubiquitination of IKBKG protein PRKN protein affects the reaction [salvin results in increased ubiquitination of IKBKG protein]
CTD
PMID:31705926
NCBI chr X:154,541,238...154,565,046
Ensembl chr X:154,541,199...154,565,046
G
INHBE
inhibin subunit beta E
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in increased expression of INHBE mRNA]
CTD
PMID:35202923
NCBI chr12:57,455,307...57,458,025
Ensembl chr12:57,452,323...57,459,280
G
INMT
indolethylamine N-methyltransferase
increases expression
ISO
salvin results in increased expression of INMT protein
CTD
PMID:35926579
NCBI chr 7:30,752,135...30,757,602
Ensembl chr 7:30,697,985...30,757,602
G
INTS3
integrator complex subunit 3
decreases expression
ISO
salvin results in decreased expression of INTS3 protein
CTD
PMID:35926579
NCBI chr 1:153,728,050...153,774,808
Ensembl chr 1:153,728,050...153,774,808
G
ITGA2
integrin subunit alpha 2
decreases expression
ISO
salvin results in decreased expression of ITGA2 protein
CTD
PMID:35926579
NCBI chr 5:52,989,352...53,094,779
Ensembl chr 5:52,989,340...53,094,779
G
ITGAM
integrin subunit alpha M
multiple interactions decreases expression
EXP ISO
[salvin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ITGAM protein; salvin promotes the reaction [Calcitriol results in increased expression of ITGAM protein]; salvin promotes the reaction [Tretinoin results in increased expression of ITGAM protein] salvin results in decreased expression of ITGAM protein
CTD
PMID:11504768 PMID:35926579
NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892
G
ITGB2
integrin subunit beta 2
decreases expression
ISO
salvin results in decreased expression of ITGB2 protein
CTD
PMID:35926579
NCBI chr21:44,885,953...44,928,815
Ensembl chr21:44,885,953...44,931,989
G
KLF12
KLF transcription factor 12
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of KLF12 mRNA]
CTD
PMID:35202923
NCBI chr13:73,686,089...74,306,045
Ensembl chr13:73,686,089...74,134,404
G
KNG1
kininogen 1
decreases expression
ISO
salvin results in decreased expression of KNG1 protein
CTD
PMID:35926579
NCBI chr 3:186,717,359...186,744,410
Ensembl chr 3:186,717,348...186,744,410
G
LAMP2
lysosomal associated membrane protein 2
decreases expression
ISO
salvin results in decreased expression of LAMP2 protein
CTD
PMID:35926579
NCBI chr X:120,426,148...120,469,349
Ensembl chr X:120,426,148...120,469,365
G
LCN2
lipocalin 2
decreases expression
ISO
salvin results in decreased expression of LCN2 protein
CTD
PMID:35926579
NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453
G
LGALS2
galectin 2
decreases expression
ISO
salvin results in decreased expression of LGALS2 protein
CTD
PMID:35926579
NCBI chr22:37,570,248...37,580,087
Ensembl chr22:37,570,248...37,582,616
G
LGALS3BP
galectin 3 binding protein
decreases expression
ISO
salvin results in decreased expression of LGALS3BP protein
CTD
PMID:35926579
NCBI chr17:78,971,255...78,979,923
Ensembl chr17:78,971,238...78,979,947
G
LGALS9
galectin 9
decreases expression
ISO
salvin results in decreased expression of LGALS9 protein
CTD
PMID:35926579
NCBI chr17:27,631,188...27,649,560
Ensembl chr17:27,629,798...27,649,560
G
LGMN
legumain
decreases expression
ISO
salvin results in decreased expression of LGMN protein
CTD
PMID:35926579
NCBI chr14:92,703,809...92,748,627
Ensembl chr14:92,703,807...92,748,679
G
LTF
lactotransferrin
decreases expression
ISO
salvin results in decreased expression of LTF protein
CTD
PMID:35926579
NCBI chr 3:46,435,645...46,485,234
Ensembl chr 3:46,435,645...46,485,234
G
LUZP1
leucine zipper protein 1
decreases expression
ISO
salvin results in decreased expression of LUZP1 protein
CTD
PMID:35926579
NCBI chr 1:23,083,642...23,178,122
Ensembl chr 1:23,084,030...23,178,152
G
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
increases expression
ISO
salvin results in increased expression of LYVE1 protein
CTD
PMID:35926579
NCBI chr11:10,556,966...10,568,665
Ensembl chr11:10,556,966...10,611,689
G
LYZ
lysozyme
decreases expression
ISO
salvin results in decreased expression of LYZ2 protein
CTD
PMID:35926579
NCBI chr12:69,348,381...69,354,234
Ensembl chr12:69,348,381...69,354,234
G
MAPK8
mitogen-activated protein kinase 8
multiple interactions
ISO
salvin inhibits the reaction [Oxidopamine results in increased phosphorylation of MAPK8 protein] salvin inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK8 protein]
CTD
PMID:25446857 PMID:29854073
NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360
G
MAPK9
mitogen-activated protein kinase 9
multiple interactions
ISO
salvin inhibits the reaction [Oxidopamine results in increased phosphorylation of MAPK9 protein]
CTD
PMID:25446857
NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099
G
MARCKSL1
MARCKS like 1
decreases expression
ISO
salvin results in decreased expression of MARCKSL1 protein
CTD
PMID:35926579
NCBI chr 1:32,333,839...32,336,233
Ensembl chr 1:32,333,839...32,336,233
G
MCM7
minichromosome maintenance complex component 7
decreases expression
ISO
salvin results in decreased expression of MCM7 protein
CTD
PMID:35926579
NCBI chr 7:100,092,728...100,101,397
Ensembl chr 7:100,092,233...100,101,940
G
MFN2
mitofusin 2
multiple interactions
EXP
salvin inhibits the reaction [Oxidopamine results in decreased expression of MFN2 protein]
CTD
PMID:31705926
NCBI chr 1:11,980,444...12,013,508
Ensembl chr 1:11,980,181...12,015,211
G
MOV10
Mov10 RNA helicase
decreases expression
ISO
salvin results in decreased expression of MOV10 protein
CTD
PMID:35926579
NCBI chr 1:112,674,439...112,700,739
Ensembl chr 1:112,673,141...112,700,756
G
MPO
myeloperoxidase
decreases expression
ISO
salvin results in decreased expression of MPO protein
CTD
PMID:35926579
NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
G
MPZL2
myelin protein zero like 2
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of MPZL2 mRNA]
CTD
PMID:35202923
NCBI chr11:118,253,416...118,264,297
Ensembl chr11:118,253,416...118,264,536
G
MRPS31
mitochondrial ribosomal protein S31
decreases expression
ISO
salvin results in decreased expression of MRPS31 protein
CTD
PMID:35926579
NCBI chr13:40,729,128...40,771,190
Ensembl chr13:40,729,128...40,771,190
G
MT-RNR1
mitochondrially encoded 12S rRNA
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in increased expression of MT-RNR1 mRNA]
CTD
PMID:35202923
NCBI chr MT:648...1,601
Ensembl chr MT:648...1,601
G
MT-RNR2
mitochondrially encoded 16S rRNA
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in increased expression of MT-RNR2 mRNA]
CTD
PMID:35202923
NCBI chr MT:1,671...3,229
Ensembl chr MT:1,671...3,229
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MTOR
mechanistic target of rapamycin kinase
decreases phosphorylation
EXP
salvin results in decreased phosphorylation of MTOR protein
CTD
PMID:25178877 PMID:28918123
NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556
G
MYLIP
myosin regulatory light chain interacting protein
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of MYLIP mRNA]
CTD
PMID:35202923
NCBI chr 6:16,129,086...16,163,887
Ensembl chr 6:16,129,086...16,148,248
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MYO1B
myosin IB
decreases expression
ISO
salvin results in decreased expression of MYO1B protein
CTD
PMID:35926579
NCBI chr 2:191,245,404...191,425,386
Ensembl chr 2:191,245,185...191,425,389
G
NDST1
N-deacetylase and N-sulfotransferase 1
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of NDST1 mRNA]
CTD
PMID:35202923
NCBI chr 5:150,497,779...150,558,211
Ensembl chr 5:150,485,818...150,558,211
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NDUFA12
NADH:ubiquinone oxidoreductase subunit A12
increases expression
ISO
salvin results in increased expression of NDUFA12 protein
CTD
PMID:35926579
NCBI chr12:94,971,333...95,003,697
Ensembl chr12:94,895,297...95,003,748
G
NELFB
negative elongation factor complex member B
decreases expression
ISO
salvin results in decreased expression of NELFB protein
CTD
PMID:35926579
NCBI chr 9:137,255,327...137,273,542
Ensembl chr 9:137,255,327...137,273,542
G
NFE2L2
NFE2 like bZIP transcription factor 2
increases activity multiple interactions
EXP
salvin results in increased activity of NFE2L2 protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin results in increased activity of NFE2L2 protein]; NFE2L2 mutant form inhibits the reaction [salvin results in increased expression of GCLC protein]; NFE2L2 mutant form inhibits the reaction [salvin results in increased expression of GCLM protein]; NFE2L2 mutant form inhibits the reaction [salvin results in increased expression of GSR protein]; NFE2L2 mutant form inhibits the reaction [salvin results in increased expression of GSTP1 protein]; NFE2L2 mutant form inhibits the reaction [salvin results in increased expression of SOD2 protein]; NFE2L2 protein promotes the reaction [salvin results in increased expression of GCLC protein]; NFE2L2 protein promotes the reaction [salvin results in increased expression of GCLM protein]; NFE2L2 protein promotes the reaction [salvin results in increased expression of GSR protein]; NFE2L2 protein promotes the reaction [salvin results in increased expression of HMOX1 protein]; NFE2L2 protein promotes the reaction [salvin results in increased expression of NQO1 protein]; NFE2L2 protein promotes the reaction [salvin results in increased expression of SOD2 protein]; salvin affects the localization of and results in increased activity of NFE2L2 protein; salvin inhibits the reaction [Acrylamide results in decreased expression of NFE2L2 mRNA]; salvin inhibits the reaction [Acrylamide results in decreased expression of NFE2L2 protein]
CTD
PMID:26577515 PMID:26686574 PMID:28159594
NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
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NFKBIA
NFKB inhibitor alpha
multiple interactions
ISO EXP
salvin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]; salvin inhibits the reaction [sodium arsenite results in increased phosphorylation of NFKBIA protein] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin results in increased phosphorylation of NFKBIA protein]; salvin results in increased phosphorylation of and results in increased degradation of NFKBIA protein
CTD
PMID:21375325 PMID:25271104 PMID:29854073
NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749
G
NLRP12
NLR family pyrin domain containing 12
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in increased expression of NLRP12 mRNA]
CTD
PMID:35202923
NCBI chr19:53,793,584...53,824,403
Ensembl chr19:53,793,741...53,824,403
G
NOS2
nitric oxide synthase 2
multiple interactions
ISO
salvin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
CTD
PMID:21375325
NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
G
NOX1
NADPH oxidase 1
decreases expression
ISO
salvin results in decreased expression of NOX1 protein
CTD
PMID:35926579
NCBI chr X:100,843,324...100,874,359
Ensembl chr X:100,843,324...100,874,359
G
NQO1
NAD(P)H quinone dehydrogenase 1
increases expression multiple interactions
ISO EXP
salvin results in increased expression of NQO1 mRNA 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin results in increased expression of NQO1 protein]; NFE2L2 protein promotes the reaction [salvin results in increased expression of NQO1 protein]; salvin inhibits the reaction [Acrylamide results in decreased expression of NQO1 mRNA]
CTD
PMID:18329808 PMID:26686574 PMID:28159594
NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
G
NR3C2
nuclear receptor subfamily 3 group C member 2
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of NR3C2 mRNA]
CTD
PMID:35202923
NCBI chr 4:148,078,764...148,445,508
Ensembl chr 4:148,078,762...148,444,698
G
NRDC
nardilysin convertase
decreases expression
ISO
salvin results in decreased expression of NRDC protein
CTD
PMID:35926579
NCBI chr 1:51,789,210...51,878,727
Ensembl chr 1:51,789,191...51,878,805
G
OAS1
2'-5'-oligoadenylate synthetase 1
increases expression
ISO
salvin results in increased expression of OAS1G protein
CTD
PMID:35926579
NCBI chr12:112,906,962...112,933,219
Ensembl chr12:112,905,856...112,933,219
G
OPA1
OPA1 mitochondrial dynamin like GTPase
multiple interactions increases expression
EXP
OPA1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in increased cleavage of CASP3 protein]]; OPA1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in increased cleavage of PARP1 protein]]; PRKN protein affects the reaction [salvin results in increased expression of OPA1 protein]; salvin inhibits the reaction [Oxidopamine results in decreased expression of OPA1 protein]
CTD
PMID:31705926
NCBI chr 3:193,593,208...193,697,811
Ensembl chr 3:193,593,144...193,697,811
G
ORM1
orosomucoid 1
decreases expression
ISO
salvin results in decreased expression of ORM1 protein
CTD
PMID:35926579
NCBI chr 9:114,323,098...114,326,479
Ensembl chr 9:114,323,098...114,326,479
G
PARP1
poly(ADP-ribose) polymerase 1
multiple interactions increases cleavage decreases expression
EXP ISO
Acetylcysteine inhibits the reaction [salvin results in increased cleavage of PARP1 protein]; OPA1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in increased cleavage of PARP1 protein]]; PINK1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in increased cleavage of PARP1 protein]]; salvin inhibits the reaction [Oxidopamine results in increased cleavage of PARP1 protein] salvin results in decreased expression of PARP1 protein
CTD
PMID:25446857 PMID:28918123 PMID:30707903 PMID:31705926
NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
G
PCBD2
pterin-4 alpha-carbinolamine dehydratase 2
increases expression
ISO
salvin results in increased expression of PCBD2 protein
CTD
PMID:35926579
NCBI chr 5:134,905,131...134,962,644
Ensembl chr 5:134,905,120...135,007,959
G
PDE5A
phosphodiesterase 5A
increases expression
ISO
salvin results in increased expression of PDE5A protein
CTD
PMID:35926579
NCBI chr 4:119,494,403...119,628,804
Ensembl chr 4:119,494,397...119,628,804
G
PER2
period circadian regulator 2
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of PER2 mRNA]
CTD
PMID:35202923
NCBI chr 2:238,244,044...238,300,065
Ensembl chr 2:238,244,044...238,290,102
G
PGAM5
PGAM family member 5, mitochondrial serine/threonine protein phosphatase
decreases expression
ISO
salvin results in decreased expression of PGAM5 protein
CTD
PMID:35926579
NCBI chr12:132,710,842...132,722,734
Ensembl chr12:132,710,819...132,722,734
G
PGLYRP1
peptidoglycan recognition protein 1
decreases expression
ISO
salvin results in decreased expression of PGLYRP1 protein
CTD
PMID:35926579
NCBI chr19:46,019,153...46,023,053
Ensembl chr19:46,019,153...46,023,053
G
PHGDH
phosphoglycerate dehydrogenase
decreases expression
ISO
salvin results in decreased expression of PHGDH protein
CTD
PMID:35926579
NCBI chr 1:119,711,934...119,744,215
Ensembl chr 1:119,648,411...119,744,218
G
PINK1
PTEN induced kinase 1
multiple interactions
EXP
PINK1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in decreased expression of BCL2 protein]]; PINK1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in decreased expression of PRKN protein]]; PINK1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in decreased expression of VDAC1 protein]]; PINK1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in increased cleavage of CASP3 protein]]; PINK1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in increased cleavage of PARP1 protein]]; salvin inhibits the reaction [Oxidopamine results in decreased expression of PINK1 protein]
CTD
PMID:30707903
NCBI chr 1:20,633,458...20,651,511
Ensembl chr 1:20,633,458...20,651,511
G
PLG
plasminogen
decreases expression
ISO
salvin results in decreased expression of PLG protein
CTD
PMID:35926579
NCBI chr 6:160,702,193...160,754,097
Ensembl chr 6:160,702,194...160,754,097
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PLIN2
perilipin 2
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in increased expression of PLIN2 mRNA]
CTD
PMID:35202923
NCBI chr 9:19,108,388...19,127,492
Ensembl chr 9:19,108,375...19,149,290
G
PLIN4
perilipin 4
increases expression
ISO
salvin results in increased expression of PLIN4 protein
CTD
PMID:35926579
NCBI chr19:4,502,192...4,518,486
Ensembl chr19:4,502,192...4,518,486
G
PLPP1
phospholipid phosphatase 1
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of PLPP1 mRNA]
CTD
PMID:35202923
NCBI chr 5:55,424,854...55,534,964
Ensembl chr 5:55,424,854...55,534,969
G
PNLIP
pancreatic lipase
decreases expression
ISO
salvin results in decreased expression of PNLIP protein
CTD
PMID:35926579
NCBI chr10:116,545,931...116,567,855
Ensembl chr10:116,545,931...116,567,855
G
PNLIPRP1
pancreatic lipase related protein 1
decreases expression
ISO
salvin results in decreased expression of PNLIPRP1 protein
CTD
PMID:35926579
NCBI chr10:116,590,959...116,609,175
Ensembl chr10:116,590,385...116,609,175
G
PPARG
peroxisome proliferator activated receptor gamma
increases activity
EXP
salvin results in increased activity of PPARG protein
CTD
PMID:20696231
NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
G
PRDX6
peroxiredoxin 6
increases expression
ISO
salvin results in increased expression of PRDX6 protein
CTD
PMID:35926579
NCBI chr 1:173,477,335...173,488,815
Ensembl chr 1:173,477,330...173,488,815
G
PRKN
parkin RBR E3 ubiquitin protein ligase
multiple interactions increases expression
EXP
PINK1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in decreased expression of PRKN protein]]; PRKN protein affects the reaction [salvin results in increased expression of OPA1 protein]; PRKN protein affects the reaction [salvin results in increased expression of RELA protein]; PRKN protein affects the reaction [salvin results in increased ubiquitination of IKBKG protein]; salvin inhibits the reaction [Oxidopamine results in decreased expression of PRKN protein] salvin results in increased expression of PRKN protein
CTD
PMID:30707903 PMID:31705926
NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775
G
PROM1
prominin 1
decreases expression
ISO
salvin results in decreased expression of PROM1 protein
CTD
PMID:35926579
NCBI chr 4:15,968,228...16,084,023
Ensembl chr 4:15,963,076...16,084,378
G
PTEN
phosphatase and tensin homolog
multiple interactions increases expression
EXP
salvin promotes the reaction [arsenic trioxide results in increased expression of PTEN mRNA] salvin results in increased expression of PTEN mRNA
CTD
PMID:23239002
NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930
G
PTGDS
prostaglandin D2 synthase
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in increased expression of PTGDS mRNA]
CTD
PMID:35202923
NCBI chr 9:136,977,504...136,981,742
Ensembl chr 9:136,975,092...136,981,742
G
PTGS2
prostaglandin-endoperoxide synthase 2
multiple interactions
ISO
salvin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]
CTD
PMID:21375325
NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
G
PVALB
parvalbumin
decreases expression
ISO
salvin results in decreased expression of PVALB protein
CTD
PMID:35926579
NCBI chr22:36,800,703...36,819,499
Ensembl chr22:36,800,684...36,819,479
G
PXDN
peroxidasin
decreases expression
ISO
salvin results in decreased expression of PXDN protein
CTD
PMID:35926579
NCBI chr 2:1,631,887...1,744,901
Ensembl chr 2:1,631,887...1,744,852
G
QSOX1
quiescin sulfhydryl oxidase 1
decreases expression
ISO
salvin results in decreased expression of QSOX1 protein
CTD
PMID:35926579
NCBI chr 1:180,154,869...180,204,030
Ensembl chr 1:180,154,869...180,204,030
G
RAB11FIP2
RAB11 family interacting protein 2
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of RAB11FIP2 mRNA]
CTD
PMID:35202923
NCBI chr10:118,004,916...118,046,941
Ensembl chr10:118,004,916...118,046,941
G
RAPGEF5
Rap guanine nucleotide exchange factor 5
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of RAPGEF5 mRNA]
CTD
PMID:35202923
NCBI chr 7:22,118,236...22,357,154
Ensembl chr 7:22,118,236...22,357,154
G
RARA
retinoic acid receptor alpha
multiple interactions
EXP
[Tetradecanoylphorbol Acetate co-treated with salvin] results in increased expression of RARA protein
CTD
PMID:11504768
NCBI chr17:40,309,180...40,357,643
Ensembl chr17:40,309,180...40,357,643
G
RBPMS
RNA binding protein, mRNA processing factor
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in increased expression of RBPMS mRNA]
CTD
PMID:35202923
NCBI chr 8:30,384,541...30,572,256
Ensembl chr 8:30,384,511...30,572,256
G
RDH16
retinol dehydrogenase 16
decreases expression
ISO
salvin results in decreased expression of RDH16 protein
CTD
PMID:35926579
NCBI chr12:56,951,431...56,957,608
Ensembl chr12:56,951,431...56,959,374
G
RELA
RELA proto-oncogene, NF-kB subunit
multiple interactions affects localization increases expression
ISO EXP
salvin inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]; salvin inhibits the reaction [sodium arsenite results in increased phosphorylation of and affects the localization of RELA protein] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin affects the localization of RELA protein]; PRKN protein affects the reaction [salvin results in increased expression of RELA protein]; salvin results in increased expression of and results in increased activity of RELA protein
CTD
PMID:21375325 PMID:25271104 PMID:29854073 PMID:31705926
NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090
G
RER1
retention in endoplasmic reticulum sorting receptor 1
increases expression
ISO
salvin results in increased expression of RER1 protein
CTD
PMID:35926579
NCBI chr 1:2,391,841...2,405,436
Ensembl chr 1:2,391,775...2,405,442
G
RHEB
Ras homolog, mTORC1 binding
decreases expression
ISO
salvin results in decreased expression of RHEB protein
CTD
PMID:35926579
NCBI chr 7:151,466,012...151,519,895
Ensembl chr 7:151,466,012...151,520,120
G
RNASE4
ribonuclease A family member 4
decreases expression
ISO
salvin results in decreased expression of RNASE4 protein
CTD
PMID:35926579
NCBI chr14:20,684,560...20,701,216
Ensembl chr14:20,684,560...20,701,216
G
RPA1
replication protein A1
decreases expression
ISO
salvin results in decreased expression of RPA1 protein
CTD
PMID:35926579
NCBI chr17:1,830,005...1,900,082
Ensembl chr17:1,829,702...1,900,082
G
RPS21
ribosomal protein S21
increases expression
ISO
salvin results in increased expression of RPS21 protein
CTD
PMID:35926579
NCBI chr20:62,387,103...62,388,520
Ensembl chr20:62,387,103...62,388,520
G
RXRA
retinoid X receptor alpha
increases expression multiple interactions
EXP
salvin results in increased expression of RXRA protein Calcitriol promotes the reaction [salvin results in increased expression of RXRA protein]; Tretinoin promotes the reaction [salvin results in increased expression of RXRA protein]
CTD
PMID:11504768
NCBI chr 9:134,326,455...134,440,585
Ensembl chr 9:134,317,098...134,440,585
G
S100A11
S100 calcium binding protein A11
decreases expression
ISO
salvin results in decreased expression of S100A11 protein
CTD
PMID:35926579
NCBI chr 1:152,032,506...152,037,004
Ensembl chr 1:152,032,506...152,047,907
G
S100A8
S100 calcium binding protein A8
decreases expression
ISO
salvin results in decreased expression of S100A8 protein
CTD
PMID:35926579
NCBI chr 1:153,390,032...153,422,583
Ensembl chr 1:153,390,032...153,391,073
G
S100A9
S100 calcium binding protein A9
decreases expression
ISO
salvin results in decreased expression of S100A9 protein
CTD
PMID:35926579
NCBI chr 1:153,357,854...153,361,023
Ensembl chr 1:153,357,854...153,361,023
G
S100G
S100 calcium binding protein G
increases expression
ISO
salvin results in increased expression of S100G protein
CTD
PMID:35926579
NCBI chr X:16,650,158...16,654,670
Ensembl chr X:16,650,158...16,654,670
G
SDC3
syndecan 3
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of SDC3 mRNA]
CTD
PMID:35202923
NCBI chr 1:30,869,466...30,909,735
Ensembl chr 1:30,869,466...30,908,758
G
SGSM3
small G protein signaling modulator 3
decreases expression
ISO
salvin results in decreased expression of SGSM3 protein
CTD
PMID:35926579
NCBI chr22:40,370,594...40,410,289
Ensembl chr22:40,370,591...40,410,289
G
SHC1
SHC adaptor protein 1
multiple interactions decreases expression increases expression
EXP
salvin inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of SHC1 protein]; SIRT1 mutant form inhibits the reaction [salvin results in decreased expression of SHC1 protein] salvin results in increased expression of SHC1 mRNA
CTD
PMID:24557422
NCBI chr 1:154,962,298...154,974,376
Ensembl chr 1:154,962,298...154,974,395
G
SHMT2
serine hydroxymethyltransferase 2
decreases expression
ISO
salvin results in decreased expression of SHMT2 protein
CTD
PMID:35926579
NCBI chr12:57,229,711...57,234,935
Ensembl chr12:57,229,573...57,234,935
G
SIK2
salt inducible kinase 2
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of SIK2 mRNA]
CTD
PMID:35202923
NCBI chr11:111,602,449...111,730,855
Ensembl chr11:111,602,449...111,730,855
G
SIRT1
sirtuin 1
multiple interactions increases expression
EXP
Niacinamide inhibits the reaction [salvin inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased expression of SIRT1 protein]]; salvin inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased expression of SIRT1 protein]; SIRT1 mutant form inhibits the reaction [salvin results in decreased expression of SHC1 protein] salvin results in increased expression of SIRT1 mRNA; salvin results in increased expression of SIRT1 protein
CTD
PMID:24557422
NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
G
SLC26A3
solute carrier family 26 member 3
increases expression
ISO
salvin results in increased expression of SLC26A3 protein
CTD
PMID:35926579
NCBI chr 7:107,765,469...107,803,223
Ensembl chr 7:107,765,467...107,803,225
G
SLC35A2
solute carrier family 35 member A2
increases expression
ISO
salvin results in increased expression of SLC35A2 protein
CTD
PMID:35926579
NCBI chr X:48,903,183...48,911,958
Ensembl chr X:48,903,180...48,911,958
G
SLTM
SAFB like transcription modulator
decreases expression
ISO
salvin results in decreased expression of SLTM protein
CTD
PMID:35926579
NCBI chr15:58,879,050...58,933,679
Ensembl chr15:58,879,050...58,933,679
G
SNW1
SNW domain containing 1
decreases expression
ISO
salvin results in decreased expression of SNW1 protein
CTD
PMID:35926579
NCBI chr14:77,717,599...77,761,156
Ensembl chr14:77,717,599...77,761,207
G
SNX4
sorting nexin 4
decreases expression
ISO
salvin results in decreased expression of SNX4 protein
CTD
PMID:35926579
NCBI chr 3:125,446,650...125,520,202
Ensembl chr 3:125,446,650...125,520,202
G
SOD1
superoxide dismutase 1
multiple interactions
EXP ISO
salvin inhibits the reaction [Acrylamide results in decreased expression of SOD1 mRNA]; salvin inhibits the reaction [Oxidopamine results in decreased expression of SOD1 protein]
CTD
PMID:25446857 PMID:28159594
NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
G
SOD2
superoxide dismutase 2
multiple interactions increases expression
EXP
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin results in increased expression of SOD2 protein]; NFE2L2 mutant form inhibits the reaction [salvin results in increased expression of SOD2 protein]; NFE2L2 protein promotes the reaction [salvin results in increased expression of SOD2 protein]; salvin inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased expression of SOD2 protein]
CTD
PMID:24557422 PMID:26577515 PMID:26686574
NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
G
SORBS1
sorbin and SH3 domain containing 1
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of SORBS1 mRNA]
CTD
PMID:35202923
NCBI chr10:95,311,773...95,561,371
Ensembl chr10:95,311,771...95,561,414
G
SPARC
secreted protein acidic and cysteine rich
decreases expression
ISO
salvin results in decreased expression of SPARC protein
CTD
PMID:35926579
NCBI chr 5:151,661,096...151,686,915
Ensembl chr 5:151,661,096...151,686,975
G
SPRR2A
small proline rich protein 2A
decreases expression
ISO
salvin results in decreased expression of SPRR2A protein
CTD
PMID:35926579
NCBI chr 1:153,056,120...153,057,512
Ensembl chr 1:153,056,120...153,057,512
G
STUB1
STIP1 homology and U-box containing protein 1
decreases expression
ISO
salvin results in decreased expression of STUB1 protein
CTD
PMID:35926579
NCBI chr16:680,410...682,801
Ensembl chr16:680,224...682,870
G
TBX3
T-box transcription factor 3
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in increased expression of TBX3 mRNA]
CTD
PMID:35202923
NCBI chr12:114,670,255...114,684,175
Ensembl chr12:114,670,255...114,684,175
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TEP1
telomerase associated protein 1
decreases expression
ISO
salvin results in decreased expression of TEP1 protein
CTD
PMID:35926579
NCBI chr14:20,365,667...20,413,501
Ensembl chr14:20,365,667...20,413,501
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TF
transferrin
decreases expression
ISO
salvin results in decreased expression of TF protein
CTD
PMID:35926579
NCBI chr 3:133,661,998...133,796,641
Ensembl chr 3:133,746,040...133,796,641
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TGM3
transglutaminase 3
increases expression
ISO
salvin results in increased expression of TGM3 protein
CTD
PMID:35926579
NCBI chr20:2,296,001...2,341,079
Ensembl chr20:2,296,001...2,341,079
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TH
tyrosine hydroxylase
multiple interactions
ISO
salvin inhibits the reaction [Oxidopamine results in decreased expression of TH protein]
CTD
PMID:25446857
NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815
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TINAGL1
tubulointerstitial nephritis antigen like 1
increases expression
ISO
salvin results in increased expression of TINAGL1 protein
CTD
PMID:35926579
NCBI chr 1:31,576,515...31,587,686
Ensembl chr 1:31,576,485...31,587,686
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TMED5
transmembrane p24 trafficking protein 5
decreases expression
ISO
salvin results in decreased expression of TMED5 protein
CTD
PMID:35926579
NCBI chr 1:93,149,742...93,180,413
Ensembl chr 1:93,149,742...93,180,516
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TMSB4X
thymosin beta 4 X-linked
decreases expression
ISO
salvin results in decreased expression of TMSB4X protein
CTD
PMID:35926579
NCBI chr X:12,975,110...12,977,223
Ensembl chr X:12,975,110...12,977,227
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TNF
tumor necrosis factor
multiple interactions
ISO
salvin inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
CTD
PMID:21375325
NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
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TNXB
tenascin XB
increases expression
ISO
salvin results in increased expression of TNXB protein
CTD
PMID:35926579
NCBI chr 6:32,041,153...32,109,338
Ensembl chr 6:32,041,153...32,115,334
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TSG101
tumor susceptibility 101
decreases expression
ISO
salvin results in decreased expression of TSG101 protein
CTD
PMID:35926579
NCBI chr11:18,480,311...18,526,942
Ensembl chr11:18,468,336...18,526,951
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TSPAN15
tetraspanin 15
increases expression
ISO
salvin results in increased expression of TSPAN15 protein
CTD
PMID:35926579
NCBI chr10:69,451,465...69,549,508
Ensembl chr10:69,451,465...69,507,666
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TXLNA
taxilin alpha
decreases expression
ISO
salvin results in decreased expression of TXLNA protein
CTD
PMID:35926579
NCBI chr 1:32,179,675...32,198,285
Ensembl chr 1:32,179,675...32,198,285
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TYR
tyrosinase
decreases expression
ISO
salvin results in decreased expression of TYR mRNA
CTD
PMID:21071833
NCBI chr11:89,177,875...89,295,759
Ensembl chr11:89,177,875...89,295,759
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UBL4A
ubiquitin like 4A
decreases expression
ISO
salvin results in decreased expression of UBL4A protein
CTD
PMID:35926579
NCBI chr X:154,483,717...154,486,615
Ensembl chr X:154,483,717...154,486,615
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VDAC1
voltage dependent anion channel 1
multiple interactions
EXP
PINK1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in decreased expression of VDAC1 protein]]; salvin inhibits the reaction [Oxidopamine results in decreased expression of and results in decreased ubiquitination of VDAC1 protein]
CTD
PMID:30707903
NCBI chr 5:133,971,871...134,114,540
Ensembl chr 5:133,971,871...134,004,975
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VDR
vitamin D receptor
multiple interactions increases expression
EXP
Calcitriol promotes the reaction [salvin results in increased expression of VDR protein]; Tetradecanoylphorbol Acetate promotes the reaction [salvin results in increased expression of VDR protein]; Tretinoin promotes the reaction [salvin results in increased expression of VDR protein]
CTD
PMID:11504768
NCBI chr12:47,841,537...47,904,994
Ensembl chr12:47,841,537...47,943,048
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VILL
villin like
decreases expression
ISO
salvin results in decreased expression of VILL protein
CTD
PMID:35926579
NCBI chr 3:37,987,978...38,007,185
Ensembl chr 3:37,988,059...38,007,188
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WDR5
WD repeat domain 5
decreases expression
ISO
salvin results in decreased expression of WDR5 protein
CTD
PMID:35926579
NCBI chr 9:134,135,199...134,159,968
Ensembl chr 9:134,135,365...134,159,968
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WIF1
WNT inhibitory factor 1
decreases expression
ISO
salvin results in decreased expression of WIF1 protein
CTD
PMID:35926579
NCBI chr12:65,050,626...65,121,305
Ensembl chr12:65,050,626...65,121,305
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ZNF207
zinc finger protein 207
decreases expression
ISO
salvin results in decreased expression of ZFP207 protein; salvin results in decreased expression of ZNF207 protein
CTD
PMID:35926579
NCBI chr17:32,350,157...32,381,885
Ensembl chr17:32,350,132...32,381,885
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