Gene: SNW1 (SNW domain containing 1)  Homo sapiens

Symbol: SNW1
Name: SNW domain containing 1
Description: This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Bx42; homolog of Drosophila BX42; MGC119379; NCOA-62; nuclear protein SkiP; nuclear receptor coactivator NCoA-62; nuclear receptor coactivator, 62-kD; OTTHUMP00000246312; OTTHUMP00000246313; OTTHUMP00000246315; Prp45; PRPF45; ski interacting protein; SKI interacting protein; SKI-interacting protein; SKIIP; SKIP; SNW domain-containing protein 1
Orthologs: Mus musculus : Snw1 (SNW domain containing 1)  MGI
Rattus norvegicus : Snw1 (SNW domain containing 1)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_11459,170,906 - 59,214,459-NCBI
Human Genome Assembly HuRef1458,349,919 - 58,393,992-NCBI
Human Genome Assembly GRCh371478,183,942 - 78,227,497-NCBI
Human Genome Assembly Build 361477,253,695 - 77,297,250-NCBI
Human Cytogenetic Map14q24.3 NCBI
Human Genome Assembly1477,253,696 - 77,297,250 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on SNW1
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 1321977
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2013-03-06
Status: ACTIVE