Gene: CLCA1 (chloride channel accessory 1) Homo sapiens
Symbol: CLCA1
Name: chloride channel accessory 1
Description: This gene encodes a member of the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same region on chromosome 1p31-p22 and share a high degree of homology in size, sequence, and predicted structure, but differ significantly in their tissue distributions. The encoded protein is expressed as a precursor protein that is processed into two cell-surface-associated subunits, although the site at which the precursor is cleaved has not been precisely determined. The encoded protein may be involved in mediating calcium-activated chloride conductance in the intestine. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CACC; CaCC-1; CACC1; calcium-activated chloride channel family member 1; calcium-activated chloride channel protein 1; calcium-activated chloride channel regulator 1; calcium-dependent chloride channel-1; chloride channel regulator 1; chloride channel, calcium activated, family member 1; CLCA family member 1, chloride channel regulator; CLCRG1; FLJ95147; GOB5; hCaCC-1; hCLCA1; OTTHUMP00000011907
Mus musculus (house mouse) : Clca1 (chloride channel accessory 1)  MGI
Rattus norvegicus (Norway rat) : Clca1 (chloride channel accessory 1)
Chinchilla lanigera (long-tailed chinchilla) : Clca1 (chloride channel accessory 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CLCA1 (chloride channel accessory 1)
Canis lupus familiaris (dog) : CLCA1 (chloride channel accessory 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38186,468,843 - 86,500,294 (+)NCBIGRCh38hg38GRCh38
GRCh37186,934,526 - 86,965,977 (+)NCBIGRCh37hg19GRCh37
Build 36186,707,114 - 86,738,565 (+)NCBINCBI36hg18NCBI36
Build 34186,646,071 - 86,677,963NCBI
Celera185,178,525 - 85,209,980 (+)NCBI
Cytogenetic Map1p22.3NCBImapview
HuRef185,045,156 - 85,076,624 (+)NCBI
CHM1_1187,049,378 - 87,080,831 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CLCA1
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 1314775
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2017-09-05
Status: ACTIVE