Gad1 Rat (+)-pilocarpine increases expression EXP 6480464 Pilocarpine results in increased expression of GAD1 mRNA CTD PMID:16797850 Gad1 Rat (-)-epigallocatechin 3-gallate increases expression EXP 6480464 epigallocatechin gallate results in increased expression of GAD1 protein CTD PMID:27659729 Gad1 Rat (R)-lipoic acid multiple interactions EXP 6480464 [Thioctic Acid co-treated with Propylthiouracil] results in increased expression of GAD1 mRNA CTD PMID:31068541 Gad1 Rat (S)-nicotine increases expression EXP 6480464 Nicotine results in increased expression of GAD1 mRNA and Nicotine results in increased expression of GAD1 protein CTD PMID:18312583 and PMID:28555334 Gad1 Rat (S)-nicotine decreases methylation EXP 6480464 Nicotine results in decreased methylation of GAD1 promoter CTD PMID:28555334 Gad1 Rat (S)-nicotine multiple interactions EXP 6480464 Dihydro-beta-Erythroidine analog inhibits the reaction [Nicotine results in increased expression of GAD1 mRNA] CTD PMID:28555334 Gad1 Rat 1-methyl-1H-imidazole decreases activity ISO Gad1 (Mus musculus) 6480464 1-methylimidazole results in decreased activity of GAD1 protein CTD PMID:19730755 Gad1 Rat 17beta-estradiol increases expression ISO GAD1 (Homo sapiens) 6480464 Estradiol results in increased expression of GAD1 mRNA CTD PMID:24758408 and PMID:31614463 Gad1 Rat 17beta-estradiol multiple interactions ISO GAD1 (Homo sapiens) 6480464 EGF protein promotes the reaction [Estradiol results in increased expression of GAD1 mRNA] CTD PMID:24758408 Gad1 Rat 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO GAD1 (Homo sapiens) 6480464 2 more ... CTD PMID:19095052 Gad1 Rat 2,2',4,4'-Tetrabromodiphenyl ether decreases expression EXP 6480464 2 more ... CTD PMID:27291303 Gad1 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of GAD1 mRNA CTD PMID:12060831 and PMID:32109520 Gad1 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Gad1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of GAD1 mRNA CTD PMID:24680724 Gad1 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO GAD1 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased expression of GAD1 mRNA CTD PMID:20106945 more ... Gad1 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO GAD1 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased expression of GAD1 mRNA CTD PMID:21296121 Gad1 Rat 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:32109520 Gad1 Rat 2-methyl-6-(phenylethynyl)pyridine multiple interactions EXP 6480464 6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Levodopa promotes the reaction [Oxidopamine results in increased expression of GAD1 mRNA]] CTD PMID:19660528 Gad1 Rat 2-METHYLIMIDAZOLE decreases activity ISO Gad1 (Mus musculus) 6480464 2-methylimidazole results in decreased activity of GAD1 protein CTD PMID:19730755 Gad1 Rat 2-palmitoylglycerol increases expression ISO GAD1 (Homo sapiens) 6480464 2-palmitoylglycerol results in increased expression of GAD1 mRNA CTD PMID:37199045 Gad1 Rat 3-Acetylpyridine increases expression EXP 6480464 3-acetylpyridine results in increased expression of GAD1 mRNA CTD PMID:8774452 Gad1 Rat 3-Acetylpyridine multiple interactions EXP 6480464 Amphetamine inhibits the reaction [3-acetylpyridine results in increased expression of GAD1 mRNA] more ... CTD PMID:8774452 Gad1 Rat 3-mercaptopropanoic acid decreases activity EXP 6480464 3-Mercaptopropionic Acid results in decreased activity of GAD1 protein CTD PMID:4154755 Gad1 Rat 3-mercaptopropanoic acid multiple interactions ISO GAD1 (Homo sapiens) 6480464 3-Mercaptopropionic Acid binds to and results in decreased activity of GAD1 protein CTD PMID:35151785 Gad1 Rat 4,4'-sulfonyldiphenol decreases methylation ISO Gad1 (Mus musculus) 6480464 bisphenol S results in decreased methylation of GAD1 exon and bisphenol S results in decreased methylation of GAD1 promoter CTD PMID:33297965 Gad1 Rat 4,4'-sulfonyldiphenol decreases methylation ISO GAD1 (Homo sapiens) 6480464 bisphenol S results in decreased methylation of GAD1 gene CTD PMID:31601247 Gad1 Rat 4-methylimidazole decreases activity ISO Gad1 (Mus musculus) 6480464 4-methylimidazole results in decreased activity of GAD1 protein CTD PMID:19730755 Gad1 Rat 5-aza-2'-deoxycytidine multiple interactions EXP 6480464 Decitabine inhibits the reaction [bisphenol A results in decreased expression of GAD1 mRNA] CTD PMID:23791455 Gad1 Rat 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of GAD1 mRNA CTD PMID:24780913 Gad1 Rat 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of GAD1 mRNA CTD PMID:30047161 Gad1 Rat 6-propyl-2-thiouracil multiple interactions EXP 6480464 [Thioctic Acid co-treated with Propylthiouracil] results in increased expression of GAD1 mRNA CTD PMID:31068541 Gad1 Rat acetic acid increases expression ISO GAD1 (Homo sapiens) 6480464 Acetic Acid results in increased expression of GAD1 mRNA CTD PMID:17065238 Gad1 Rat acrylamide decreases expression ISO GAD1 (Homo sapiens) 6480464 Acrylamide results in decreased expression of GAD1 mRNA CTD PMID:32763439 Gad1 Rat aldehydo-D-glucose multiple interactions EXP 6480464 GAD1 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] CTD PMID:25966616 Gad1 Rat all-trans-retinoic acid decreases expression ISO GAD1 (Homo sapiens) 6480464 Tretinoin results in decreased expression of GAD1 mRNA CTD PMID:21934132 Gad1 Rat all-trans-retinoic acid increases expression ISO Gad1 (Mus musculus) 6480464 Tretinoin results in increased expression of GAD1 mRNA and Tretinoin results in increased expression of GAD1 protein alternative form CTD PMID:11841568 and PMID:22466603 Gad1 Rat amitrole multiple interactions EXP 6480464 Amitrole promotes the reaction [Sodium Chloride and Dietary results in decreased expression of GAD1 protein] CTD PMID:25891026 Gad1 Rat amitrole decreases expression EXP 6480464 Amitrole results in decreased expression of GAD1 mRNA CTD PMID:30047161 Gad1 Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of GAD1 mRNA CTD PMID:16483693 Gad1 Rat amphetamine increases expression EXP 6480464 Amphetamine results in increased expression of GAD1 mRNA and Amphetamine results in increased expression of GAD1 protein CTD PMID:14725721 and PMID:18312583 Gad1 Rat amphetamine affects expression ISO Gad1 (Mus musculus) 6480464 Amphetamine affects the expression of GAD1 protein CTD PMID:19059431 Gad1 Rat amphetamine increases expression ISO Gad1 (Mus musculus) 6480464 Amphetamine results in increased expression of GAD1 mRNA CTD PMID:23660488 Gad1 Rat amphetamine multiple interactions EXP 6480464 Amphetamine inhibits the reaction [3-acetylpyridine results in increased expression of GAD1 mRNA] and Propranolol inhibits the reaction [Amphetamine inhibits the reaction [3-acetylpyridine results in increased expression of GAD1 mRNA]] CTD PMID:8774452 Gad1 Rat apocynin multiple interactions ISO Gad1 (Mus musculus) 6480464 acetovanillone inhibits the reaction [Ketamine results in decreased expression of GAD1 protein] CTD PMID:18063801 Gad1 Rat Aroclor 1254 multiple interactions EXP 6480464 [aroclor 1242 co-treated with aroclor 1248 co-treated with Chlorodiphenyl (54% Chlorine) co-treated with aroclor 1260] results in decreased expression of GAD1 protein CTD PMID:17324953 Gad1 Rat atrazine increases expression EXP 6480464 Atrazine results in increased expression of GAD1 mRNA CTD PMID:36071823 Gad1 Rat belinostat increases expression ISO GAD1 (Homo sapiens) 6480464 belinostat results in increased expression of GAD1 mRNA CTD PMID:26272509 Gad1 Rat belinostat multiple interactions ISO GAD1 (Homo sapiens) 6480464 [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GAD1 mRNA CTD PMID:27188386 Gad1 Rat benzo[a]pyrene increases expression ISO GAD1 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of GAD1 mRNA CTD PMID:20106945 more ... Gad1 Rat benzo[a]pyrene increases methylation ISO GAD1 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of GAD1 promoter CTD PMID:27901495 Gad1 Rat bis(2-chloroethyl) sulfide increases expression ISO Gad1 (Mus musculus) 6480464 Mustard Gas results in increased expression of GAD1 mRNA CTD PMID:15674844 Gad1 Rat bis(2-ethylhexyl) phthalate decreases expression ISO GAD1 (Homo sapiens) 6480464 Diethylhexyl Phthalate results in decreased expression of GAD1 mRNA CTD PMID:31163220 Gad1 Rat bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of GAD1 mRNA CTD PMID:25181051 and PMID:26950200 Gad1 Rat bisphenol A decreases expression ISO Gad1 (Mus musculus) 6480464 bisphenol A results in decreased expression of GAD1 mRNA CTD PMID:32156529 Gad1 Rat bisphenol A multiple interactions ISO GAD1 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of GAD1 gene CTD PMID:31601247 Gad1 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of GAD1 mRNA and bisphenol A results in increased expression of GAD1 protein CTD PMID:37926988 Gad1 Rat bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of GAD1 gene CTD PMID:28505145 Gad1 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of GAD1 mRNA CTD PMID:18180321 and PMID:23791455 Gad1 Rat bisphenol A multiple interactions EXP 6480464 decitabine inhibits the reaction [bisphenol A results in decreased expression of GAD1 mRNA] CTD PMID:23791455 Gad1 Rat butanal increases expression ISO GAD1 (Homo sapiens) 6480464 butyraldehyde results in increased expression of GAD1 mRNA CTD PMID:26079696 Gad1 Rat cadmium dichloride increases expression ISO GAD1 (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of GAD1 mRNA CTD PMID:12160620 Gad1 Rat caffeine increases expression EXP 6480464 Caffeine results in increased expression of GAD1 mRNA and Caffeine results in increased expression of GAD1 protein CTD PMID:35917217 Gad1 Rat cannabidiol multiple interactions EXP 6480464 Cannabidiol inhibits the reaction [Poly I-C results in decreased expression of GAD1 protein] CTD PMID:31202911 Gad1 Rat carbamazepine affects expression ISO GAD1 (Homo sapiens) 6480464 Carbamazepine affects the expression of GAD1 mRNA CTD PMID:25979313 Gad1 Rat chaetocin multiple interactions EXP 6480464 chaetocin affects the reaction [Dronabinol affects the expression of GAD1 mRNA] CTD PMID:29022873 and PMID:29481316 Gad1 Rat chlorpromazine decreases methylation ISO Gad1 (Mus musculus) 6480464 Chlorpromazine results in decreased methylation of GAD1 promoter CTD PMID:19110320 Gad1 Rat chlorpromazine multiple interactions ISO Gad1 (Mus musculus) 6480464 Valproic Acid promotes the reaction [Chlorpromazine results in decreased methylation of GAD1 promoter] CTD PMID:19110320 Gad1 Rat chlorpyrifos increases expression ISO Gad1 (Mus musculus) 6480464 Chlorpyrifos results in increased expression of GAD1 mRNA CTD PMID:36113784 Gad1 Rat chlorpyrifos affects binding ISO GAD1 (Homo sapiens) 6480464 Chlorpyrifos binds to [GAD1 protein binds to Pyridoxal Phosphate] and Chlorpyrifos binds to GAD1 protein CTD PMID:35151785 Gad1 Rat cisplatin increases expression ISO GAD1 (Homo sapiens) 6480464 Cisplatin results in increased expression of GAD1 mRNA CTD PMID:27392435 Gad1 Rat cisplatin multiple interactions ISO GAD1 (Homo sapiens) 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of GAD1 mRNA CTD PMID:27392435 Gad1 Rat clenbuterol multiple interactions EXP 6480464 Clenbuterol inhibits the reaction [3-acetylpyridine results in increased expression of GAD1 mRNA] more ... CTD PMID:8774452 Gad1 Rat clozapine increases expression ISO GAD1 (Homo sapiens) 6480464 Clozapine results in increased expression of GAD1 mRNA CTD PMID:17942719 Gad1 Rat clozapine increases expression EXP 6480464 Clozapine results in increased expression of GAD1 mRNA CTD PMID:12887421 more ... Gad1 Rat clozapine decreases methylation ISO Gad1 (Mus musculus) 6480464 Clozapine results in decreased methylation of GAD1 promoter CTD PMID:18757738 Gad1 Rat clozapine multiple interactions ISO Gad1 (Mus musculus) 6480464 Clozapine promotes the reaction [KMT2A protein binds to GAD1 promoter] and Valproic Acid promotes the reaction [Clozapine results in decreased methylation of GAD1 promoter] CTD PMID:17942719 and PMID:18757738 Gad1 Rat cobalt dichloride decreases expression ISO GAD1 (Homo sapiens) 6480464 cobaltous chloride results in decreased expression of GAD1 mRNA CTD PMID:22941251 Gad1 Rat cobalt dichloride decreases expression ISO Gad1 (Mus musculus) 6480464 cobaltous chloride results in decreased expression of GAD1 protein CTD PMID:29107683 Gad1 Rat cocaine decreases expression ISO GAD1 (Homo sapiens) 6480464 Cocaine results in decreased expression of GAD1 mRNA CTD PMID:12629581 Gad1 Rat cocaine increases expression EXP 6480464 Cocaine results in increased expression of GAD1 protein CTD PMID:15295023 and PMID:18611417 Gad1 Rat corticosterone multiple interactions ISO Gad1 (Mus musculus) 6480464 GAD1 affects the reaction [2 more ... CTD PMID:21219938 Gad1 Rat corticosterone increases expression EXP 6480464 Corticosterone results in increased expression of GAD1 mRNA CTD PMID:32437893 Gad1 Rat Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of GAD1 mRNA CTD PMID:26577399 Gad1 Rat curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [Streptozocin results in decreased expression of GAD1 mRNA] CTD PMID:23267840 Gad1 Rat cyclosporin A decreases expression ISO GAD1 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of GAD1 mRNA CTD PMID:27989131 Gad1 Rat cypermethrin decreases expression EXP 6480464 cypermethrin results in decreased expression of GAD1 mRNA and cypermethrin results in decreased expression of GAD1 protein CTD PMID:26115703 Gad1 Rat cyproconazole decreases expression EXP 6480464 cyproconazole results in decreased expression of GAD1 mRNA CTD PMID:25182419 Gad1 Rat D-glucose multiple interactions EXP 6480464 GAD1 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] CTD PMID:25966616 Gad1 Rat dexamethasone increases expression EXP 6480464 Dexamethasone results in increased expression of GAD1 mRNA and Dexamethasone results in increased expression of GAD1 protein CTD PMID:31518422 and PMID:32445661 Gad1 Rat dexamethasone multiple interactions EXP 6480464 BDNF protein inhibits the reaction [Dexamethasone results in increased expression of GAD1 mRNA] and Mifepristone inhibits the reaction [Dexamethasone results in increased expression of GAD1 mRNA] CTD PMID:31518422 and PMID:32445661 Gad1 Rat dextran sulfate multiple interactions ISO Gad1 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GAD1 mRNA CTD PMID:29950665 Gad1 Rat diazepam decreases expression EXP 6480464 Diazepam results in decreased expression of GAD1 mRNA CTD PMID:15802192 Gad1 Rat diazinon affects binding ISO GAD1 (Homo sapiens) 6480464 Diazinon binds to [GAD1 protein binds to Pyridoxal Phosphate] and Diazinon binds to GAD1 protein CTD PMID:35151785 Gad1 Rat dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of GAD1 mRNA CTD PMID:15620428 Gad1 Rat dihydro-beta-erythroidine multiple interactions EXP 6480464 Dihydro-beta-Erythroidine analog inhibits the reaction [Nicotine results in increased expression of GAD1 mRNA] CTD PMID:28555334 Gad1 Rat diisopropyl fluorophosphate affects binding ISO GAD1 (Homo sapiens) 6480464 Isoflurophate binds to [GAD1 protein binds to Pyridoxal Phosphate] and Isoflurophate binds to GAD1 protein CTD PMID:35151785 Gad1 Rat dimethyl sulfoxide increases expression ISO GAD1 (Homo sapiens) 6480464 Dimethyl Sulfoxide results in increased expression of GAD1 mRNA CTD PMID:17065238 Gad1 Rat dioxygen multiple interactions EXP 6480464 GAD1 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] CTD PMID:25966616 Gad1 Rat dioxygen multiple interactions ISO Gad1 (Mus musculus) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Oxygen deficiency results in decreased expression of GAD1 protein] more ... CTD PMID:29107683 Gad1 Rat dioxygen decreases expression ISO Gad1 (Mus musculus) 6480464 Oxygen deficiency results in decreased expression of GAD1 mRNA CTD PMID:29107683 Gad1 Rat dioxygen increases expression ISO GAD1 (Homo sapiens) 6480464 Oxygen deficiency results in increased expression of GAD1 mRNA CTD PMID:26516004 Gad1 Rat disodium selenite decreases expression ISO Gad1 (Mus musculus) 6480464 Sodium Selenite results in decreased expression of GAD1 mRNA CTD PMID:23274088 Gad1 Rat dizocilpine maleate multiple interactions ISO Gad1 (Mus musculus) 6480464 Dizocilpine Maleate inhibits the reaction [Oxygen deficiency results in decreased expression of GAD1 protein] CTD PMID:29107683 Gad1 Rat dorsomorphin multiple interactions ISO GAD1 (Homo sapiens) 6480464 [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 Gad1 Rat doxorubicin increases expression ISO GAD1 (Homo sapiens) 6480464 Doxorubicin results in increased expression of GAD1 mRNA CTD PMID:17065238 Gad1 Rat entinostat multiple interactions ISO GAD1 (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GAD1 mRNA CTD PMID:27188386 Gad1 Rat entinostat increases expression ISO GAD1 (Homo sapiens) 6480464 entinostat results in increased expression of GAD1 mRNA CTD PMID:26272509 Gad1 Rat ethanol increases expression EXP 6480464 Ethanol results in increased expression of GAD1 mRNA CTD PMID:15729141 and PMID:32437893 Gad1 Rat ethanol multiple interactions ISO Gad1 (Mus musculus) 6480464 Ethanol affects the expression of and affects the splicing of GAD1 mRNA CTD PMID:30319688 Gad1 Rat ethanol increases expression ISO Gad1 (Mus musculus) 6480464 Ethanol results in increased expression of GAD1 protein CTD PMID:29044621 Gad1 Rat eticlopride(1+) increases expression EXP 6480464 eticlopride results in increased expression of GAD1 mRNA CTD PMID:15044549 Gad1 Rat fenamidone decreases expression ISO Gad1 (Mus musculus) 6480464 fenamidone results in decreased expression of GAD1 mRNA CTD PMID:27029645 Gad1 Rat fluoxetine increases expression EXP 6480464 Fluoxetine results in increased expression of GAD1 mRNA CTD PMID:17033635 Gad1 Rat fluvoxamine multiple interactions EXP 6480464 [Haloperidol co-treated with Fluvoxamine] affects the expression of GAD1 protein CTD PMID:15967061 Gad1 Rat folic acid decreases expression ISO Gad1 (Mus musculus) 6480464 Folic Acid results in decreased expression of GAD1 protein CTD PMID:26547318 Gad1 Rat fonofos increases methylation ISO GAD1 (Homo sapiens) 6480464 Fonofos results in increased methylation of GAD1 promoter CTD PMID:22847954 Gad1 Rat fulvestrant multiple interactions ISO GAD1 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of GAD1 gene CTD PMID:31601247 Gad1 Rat furan increases methylation EXP 6480464 furan results in increased methylation of GAD1 gene CTD PMID:22079235 Gad1 Rat furosemide decreases expression EXP 6480464 Furosemide results in decreased expression of GAD1 mRNA CTD PMID:14596865 Gad1 Rat gamma-aminobutyric acid increases chemical synthesis ISO GAD1 (Homo sapiens) 6480464 GAD1 protein results in increased chemical synthesis of gamma-Aminobutyric Acid CTD PMID:15571623 Gad1 Rat gamma-aminobutyric acid decreases expression EXP 6480464 gamma-Aminobutyric Acid results in decreased expression of GAD1 mRNA CTD PMID:26924987 Gad1 Rat genistein decreases expression EXP 6480464 Genistein results in decreased expression of GAD1 mRNA CTD PMID:21782745 Gad1 Rat glucose multiple interactions EXP 6480464 GAD1 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] CTD PMID:25966616 Gad1 Rat glyphosate affects binding ISO GAD1 (Homo sapiens) 6480464 Glyphosate binds to [GAD1 protein binds to Pyridoxal Phosphate] and Glyphosate binds to GAD1 protein CTD PMID:35151785 Gad1 Rat haloperidol multiple interactions EXP 6480464 [Haloperidol co-treated with Fluvoxamine] affects the expression of GAD1 protein CTD PMID:15967061 Gad1 Rat haloperidol increases expression EXP 6480464 Haloperidol results in increased expression of GAD1 mRNA CTD PMID:12887421 more ... Gad1 Rat haloperidol decreases expression EXP 6480464 Haloperidol results in decreased expression of GAD1 mRNA and Haloperidol results in decreased expression of GAD1 protein CTD PMID:14519413 and PMID:19359144 Gad1 Rat hexadecanoic acid increases expression ISO GAD1 (Homo sapiens) 6480464 Palmitic Acid results in increased expression of GAD1 mRNA CTD PMID:37199045 Gad1 Rat hydrogen peroxide decreases response to substance ISO GAD1 (Homo sapiens) 6480464 GAD1 protein results in decreased susceptibility to Hydrogen Peroxide CTD PMID:15369822 Gad1 Rat hydrogen peroxide affects expression ISO GAD1 (Homo sapiens) 6480464 Hydrogen Peroxide affects the expression of GAD1 mRNA CTD PMID:20044591 Gad1 Rat kainic acid increases expression EXP 6480464 Kainic Acid results in increased expression of GAD1 mRNA CTD PMID:16797850 Gad1 Rat ketamine multiple interactions ISO Gad1 (Mus musculus) 6480464 acetovanillone inhibits the reaction [Ketamine results in decreased expression of GAD1 protein] CTD PMID:18063801 Gad1 Rat ketamine increases expression ISO Gad1 (Mus musculus) 6480464 Ketamine results in increased expression of GAD1 mRNA CTD PMID:23660488 Gad1 Rat ketamine decreases expression ISO Gad1 (Mus musculus) 6480464 Ketamine results in decreased expression of GAD1 CTD PMID:18063801 Gad1 Rat ketoconazole decreases expression ISO Gad1 (Mus musculus) 6480464 Ketoconazole results in decreased expression of GAD1 mRNA CTD PMID:31099283 Gad1 Rat L-glutamic acid multiple interactions ISO GAD1 (Homo sapiens) 6480464 [GAD1 protein binds to Pyridoxal Phosphate] which binds to and results in increased metabolism of Glutamic Acid CTD PMID:35151785 Gad1 Rat L-methionine decreases expression ISO Gad1 (Mus musculus) 6480464 Methionine results in decreased expression of GAD1 more ... CTD PMID:15671176 more ... Gad1 Rat L-methionine multiple interactions ISO Gad1 (Mus musculus) 6480464 Methionine promotes the reaction [MECP2 binds to GAD1 promoter] and Valproic Acid inhibits the reaction [Methionine results in decreased expression of GAD1 protein] CTD PMID:16113080 and PMID:20442623 Gad1 Rat lead(0) decreases expression EXP 6480464 Lead results in decreased expression of GAD1 protein CTD PMID:15149801 Gad1 Rat lead(0) affects expression ISO GAD1 (Homo sapiens) 6480464 Lead affects the expression of GAD1 mRNA CTD PMID:28903495 Gad1 Rat leflunomide increases expression ISO GAD1 (Homo sapiens) 6480464 leflunomide results in increased expression of GAD1 mRNA CTD PMID:28988120 Gad1 Rat lipoic acid multiple interactions EXP 6480464 [Thioctic Acid co-treated with Propylthiouracil] results in increased expression of GAD1 mRNA CTD PMID:31068541 Gad1 Rat malathion affects binding ISO GAD1 (Homo sapiens) 6480464 Malathion binds to [GAD1 protein binds to Pyridoxal Phosphate] and Malathion binds to GAD1 protein CTD PMID:35151785 Gad1 Rat manganese(II) chloride decreases expression EXP 6480464 manganese chloride results in decreased expression of GAD1 mRNA CTD PMID:12106697 Gad1 Rat metformin multiple interactions EXP 6480464 Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of GAD1 protein] CTD PMID:35085591 Gad1 Rat methimazole decreases expression EXP 6480464 Methimazole results in decreased expression of GAD1 mRNA CTD PMID:30047161 Gad1 Rat methotrexate affects response to substance ISO GAD1 (Homo sapiens) 6480464 GAD1 protein affects the susceptibility to Methotrexate CTD PMID:16217747 Gad1 Rat methotrexate decreases expression ISO GAD1 (Homo sapiens) 6480464 Methotrexate results in decreased expression of GAD1 mRNA CTD PMID:24449571 Gad1 Rat methylazoxymethanol decreases expression EXP 6480464 methylazoxymethanol results in decreased expression of GAD1 mRNA CTD PMID:23932495 Gad1 Rat methylmercury chloride decreases expression ISO Gad1 (Mus musculus) 6480464 methylmercuric chloride results in decreased expression of GAD1 mRNA CTD PMID:21385734 Gad1 Rat methylmercury chloride multiple interactions ISO GAD1 (Homo sapiens) 6480464 [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GAD1 mRNA CTD PMID:27188386 Gad1 Rat methylmercury chloride increases expression ISO GAD1 (Homo sapiens) 6480464 methylmercuric chloride results in increased expression of GAD1 mRNA CTD PMID:23179753 and PMID:26272509 Gad1 Rat mifepristone multiple interactions EXP 6480464 Mifepristone inhibits the reaction [Dexamethasone results in increased expression of GAD1 mRNA] CTD PMID:32445661 Gad1 Rat Mipafox affects binding ISO GAD1 (Homo sapiens) 6480464 mipafox binds to [GAD1 protein binds to Pyridoxal Phosphate] and mipafox binds to GAD1 protein CTD PMID:35151785 Gad1 Rat monosodium L-glutamate decreases expression EXP 6480464 Sodium Glutamate results in decreased expression of GAD1 mRNA CTD PMID:19733649 Gad1 Rat monosodium L-glutamate increases expression EXP 6480464 Sodium Glutamate results in increased expression of GAD1 protein CTD PMID:19733649 Gad1 Rat morphine increases expression EXP 6480464 Morphine results in increased expression of GAD1 mRNA CTD PMID:15673448 and PMID:18312583 Gad1 Rat N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO Gad1 (Mus musculus) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Oxygen deficiency results in decreased expression of GAD1 protein] CTD PMID:29107683 Gad1 Rat N-ethylmaleimide decreases activity ISO GAD1 (Homo sapiens) 6480464 Ethylmaleimide results in decreased activity of GAD1 protein CTD PMID:15836621 Gad1 Rat nickel sulfate increases expression ISO GAD1 (Homo sapiens) 6480464 nickel sulfate results in increased expression of GAD1 mRNA CTD PMID:22714537 Gad1 Rat nicotine increases expression EXP 6480464 Nicotine results in increased expression of GAD1 mRNA and Nicotine results in increased expression of GAD1 protein CTD PMID:18312583 and PMID:28555334 Gad1 Rat nicotine decreases methylation EXP 6480464 Nicotine results in decreased methylation of GAD1 promoter CTD PMID:28555334 Gad1 Rat nicotine multiple interactions EXP 6480464 Dihydro-beta-Erythroidine analog inhibits the reaction [Nicotine results in increased expression of GAD1 mRNA] CTD PMID:28555334 Gad1 Rat Nonylphenol increases expression EXP 6480464 nonylphenol results in increased expression of GAD1 mRNA CTD PMID:15620428 Gad1 Rat O-methyleugenol increases expression ISO GAD1 (Homo sapiens) 6480464 methyleugenol results in increased expression of GAD1 mRNA CTD PMID:32234424 Gad1 Rat olanzapine decreases expression EXP 6480464 olanzapine results in decreased expression of GAD1 mRNA and olanzapine results in decreased expression of GAD1 protein CTD PMID:14519413 and PMID:19359144 Gad1 Rat oxidopamine multiple interactions EXP 6480464 6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Levodopa promotes the reaction [Oxidopamine results in increased expression of GAD1 mRNA]] more ... CTD PMID:17241287 and PMID:19660528 Gad1 Rat oxidopamine increases expression EXP 6480464 Oxidopamine results in increased expression of GAD1 mRNA CTD PMID:12077209 more ... Gad1 Rat panobinostat multiple interactions ISO GAD1 (Homo sapiens) 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GAD1 mRNA CTD PMID:27188386 Gad1 Rat panobinostat increases expression ISO GAD1 (Homo sapiens) 6480464 panobinostat results in increased expression of GAD1 mRNA CTD PMID:26272509 Gad1 Rat paracetamol affects expression ISO Gad1 (Mus musculus) 6480464 Acetaminophen affects the expression of GAD1 mRNA CTD PMID:17562736 Gad1 Rat paraoxon affects binding ISO GAD1 (Homo sapiens) 6480464 Paraoxon binds to [GAD1 protein binds to Pyridoxal Phosphate] and Paraoxon binds to GAD1 protein CTD PMID:35151785 Gad1 Rat paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of GAD1 mRNA CTD PMID:17493592 Gad1 Rat parathion increases methylation ISO GAD1 (Homo sapiens) 6480464 Parathion results in increased methylation of GAD1 promoter CTD PMID:22847954 Gad1 Rat pentanal increases expression ISO GAD1 (Homo sapiens) 6480464 pentanal results in increased expression of GAD1 mRNA CTD PMID:26079696 Gad1 Rat pentane-2,3-dione decreases expression EXP 6480464 2 and 3-pentanedione results in decreased expression of GAD1 mRNA CTD PMID:25710175 Gad1 Rat perfluorooctanoic acid decreases expression ISO Gad1 (Mus musculus) 6480464 perfluorooctanoic acid results in decreased expression of GAD1 mRNA CTD PMID:20118188 Gad1 Rat perfluorooctanoic acid increases expression ISO GAD1 (Homo sapiens) 6480464 perfluorooctanoic acid results in increased expression of GAD1 mRNA CTD PMID:23978341 Gad1 Rat phenylmercury acetate decreases expression ISO GAD1 (Homo sapiens) 6480464 Phenylmercuric Acetate results in decreased expression of GAD1 mRNA CTD PMID:26272509 Gad1 Rat phenylmercury acetate multiple interactions ISO GAD1 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GAD1 mRNA CTD PMID:27188386 Gad1 Rat picrotoxin increases expression EXP 6480464 Picrotoxin results in increased expression of GAD1 mRNA CTD PMID:15170462 Gad1 Rat poly(I:C) multiple interactions EXP 6480464 Cannabidiol inhibits the reaction [Poly I-C results in decreased expression of GAD1 protein] CTD PMID:31202911 Gad1 Rat poly(I:C) decreases expression EXP 6480464 Poly I-C results in decreased expression of GAD1 protein CTD PMID:31202911 Gad1 Rat propanal increases expression ISO GAD1 (Homo sapiens) 6480464 propionaldehyde results in increased expression of GAD1 mRNA CTD PMID:26079696 Gad1 Rat propranolol multiple interactions EXP 6480464 Propranolol inhibits the reaction [Amphetamine inhibits the reaction [3-acetylpyridine results in increased expression of GAD1 mRNA]] and Propranolol inhibits the reaction [Clenbuterol inhibits the reaction [3-acetylpyridine results in increased expression of GAD1 mRNA]] CTD PMID:8774452 Gad1 Rat pyridoxal 5'-phosphate affects binding ISO GAD1 (Homo sapiens) 6480464 Chlorpyrifos binds to [GAD1 protein binds to Pyridoxal Phosphate] more ... CTD PMID:15686475 and PMID:35151785 Gad1 Rat pyridoxal 5'-phosphate multiple interactions ISO GAD1 (Homo sapiens) 6480464 [GAD1 protein binds to Pyridoxal Phosphate] which binds to and results in increased metabolism of Glutamic Acid CTD PMID:35151785 Gad1 Rat pyridoxal 5'-phosphate decreases activity EXP 6480464 Pyridoxal Phosphate results in decreased activity of GAD1 protein CTD PMID:7463050 Gad1 Rat pyridoxal 5'-phosphate increases activity ISO Gad1 (Mus musculus) 6480464 Pyridoxal Phosphate results in increased activity of GAD1 protein CTD PMID:171340 Gad1 Rat quercetin increases expression ISO GAD1 (Homo sapiens) 6480464 Quercetin results in increased expression of GAD1 mRNA CTD PMID:21632981 Gad1 Rat raloxifene multiple interactions ISO GAD1 (Homo sapiens) 6480464 [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of GAD1 mRNA CTD PMID:19059307 Gad1 Rat reserpine increases expression EXP 6480464 Reserpine results in increased expression of GAD1 mRNA CTD PMID:8774452 Gad1 Rat reserpine multiple interactions EXP 6480464 Clenbuterol inhibits the reaction [Reserpine results in increased expression of GAD1 mRNA] CTD PMID:8774452 Gad1 Rat sarin affects binding ISO GAD1 (Homo sapiens) 6480464 Sarin binds to [GAD1 protein binds to Pyridoxal Phosphate] and Sarin binds to GAD1 protein CTD PMID:35151785 Gad1 Rat SB 431542 multiple interactions ISO GAD1 (Homo sapiens) 6480464 [FGF2 protein co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 and PMID:32733202 Gad1 Rat sodium arsenite increases expression ISO GAD1 (Homo sapiens) 6480464 sodium arsenite results in increased expression of GAD1 mRNA CTD PMID:22714537 and PMID:29301061 Gad1 Rat sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of GAD1 mRNA CTD PMID:20376865 Gad1 Rat Soman affects binding ISO GAD1 (Homo sapiens) 6480464 Soman binds to [GAD1 protein binds to Pyridoxal Phosphate] and Soman binds to GAD1 protein CTD PMID:35151785 Gad1 Rat sotorasib multiple interactions ISO GAD1 (Homo sapiens) 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GAD1 mRNA CTD PMID:36139627 Gad1 Rat streptozocin multiple interactions EXP 6480464 [Streptozocin co-treated with Dietary Fats] results in decreased expression of GAD1 protein more ... CTD PMID:23267840 and PMID:35085591 Gad1 Rat streptozocin decreases expression EXP 6480464 Streptozocin results in decreased expression of GAD1 mRNA CTD PMID:23267840 Gad1 Rat sulfadimethoxine decreases expression EXP 6480464 Sulfadimethoxine results in decreased expression of GAD1 mRNA CTD PMID:30047161 Gad1 Rat sulpiride decreases methylation ISO Gad1 (Mus musculus) 6480464 Sulpiride results in decreased methylation of GAD1 promoter CTD PMID:18757738 Gad1 Rat sulpiride multiple interactions ISO Gad1 (Mus musculus) 6480464 Valproic Acid promotes the reaction [Sulpiride results in decreased methylation of GAD1 promoter] CTD PMID:18757738 Gad1 Rat tamoxifen multiple interactions ISO GAD1 (Homo sapiens) 6480464 [Tamoxifen co-treated with ESR2 protein] results in increased expression of GAD1 mRNA CTD PMID:19059307 Gad1 Rat terbufos increases methylation ISO GAD1 (Homo sapiens) 6480464 terbufos results in increased methylation of GAD1 promoter CTD PMID:22847954 Gad1 Rat testosterone increases expression EXP 6480464 Testosterone results in increased expression of GAD1 mRNA CTD PMID:21281643 Gad1 Rat titanium dioxide multiple interactions ISO Gad1 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GAD1 mRNA CTD PMID:29950665 Gad1 Rat toluene affects expression EXP 6480464 Toluene affects the expression of GAD1 mRNA CTD PMID:21827849 Gad1 Rat trametinib multiple interactions ISO GAD1 (Homo sapiens) 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of GAD1 mRNA CTD PMID:36139627 Gad1 Rat trichostatin A increases expression ISO GAD1 (Homo sapiens) 6480464 trichostatin A results in increased expression of GAD1 mRNA CTD PMID:24935251 and PMID:26272509 Gad1 Rat trichostatin A multiple interactions ISO GAD1 (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GAD1 mRNA CTD PMID:27188386 Gad1 Rat triphenyl phosphate decreases expression EXP 6480464 triphenyl phosphate results in decreased expression of GAD1 mRNA CTD PMID:33078273 Gad1 Rat triptonide increases expression ISO Gad1 (Mus musculus) 6480464 triptonide results in increased expression of GAD1 mRNA CTD PMID:33045310 Gad1 Rat valproic acid multiple interactions ISO Gad1 (Mus musculus) 6480464 Valproic Acid inhibits the reaction [MECP2 binds to GAD1 promoter] more ... CTD PMID:16113080 more ... Gad1 Rat valproic acid decreases expression ISO GAD1 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of GAD1 mRNA CTD PMID:34742744 Gad1 Rat valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of GAD1 mRNA CTD PMID:34779009 Gad1 Rat valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of GAD1 mRNA and Valproic Acid results in decreased expression of GAD1 protein CTD PMID:30404997 and PMID:32428529 Gad1 Rat valproic acid decreases expression ISO Gad1 (Mus musculus) 6480464 Valproic Acid results in decreased expression of GAD1 mRNA CTD PMID:24896083 Gad1 Rat valproic acid affects expression ISO GAD1 (Homo sapiens) 6480464 Valproic Acid affects the expression of GAD1 mRNA CTD PMID:25979313 Gad1 Rat valproic acid increases expression ISO GAD1 (Homo sapiens) 6480464 Valproic Acid results in increased expression of GAD1 mRNA CTD PMID:23179753 more ... Gad1 Rat valproic acid decreases methylation ISO Gad1 (Mus musculus) 6480464 Valproic Acid results in decreased methylation of GAD1 promoter CTD PMID:20716949 Gad1 Rat valproic acid increases expression ISO Gad1 (Mus musculus) 6480464 Valproic Acid results in increased expression of GAD1 mRNA CTD PMID:15737665 Gad1 Rat vigabatrin increases expression EXP 6480464 Vigabatrin results in increased expression of GAD1 protein CTD PMID:11673025 Gad1 Rat vorinostat increases expression ISO GAD1 (Homo sapiens) 6480464 vorinostat results in increased expression of GAD1 mRNA CTD PMID:26272509 Gad1 Rat vorinostat multiple interactions ISO GAD1 (Homo sapiens) 6480464 [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GAD1 mRNA CTD PMID:27188386 Gad1 Rat VX nerve agent affects binding ISO GAD1 (Homo sapiens) 6480464 VX binds to [GAD1 protein binds to Pyridoxal Phosphate] and VX binds to GAD1 protein CTD PMID:35151785 Gad1 Rat zinc atom increases expression ISO GAD1 (Homo sapiens) 6480464 Zinc deficiency results in increased expression of GAD1 mRNA CTD PMID:18356318 Gad1 Rat zinc(0) increases expression ISO GAD1 (Homo sapiens) 6480464 Zinc deficiency results in increased expression of GAD1 mRNA CTD PMID:18356318