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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2652
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gad1
Name: glutamate decarboxylase 1
Acc ID: CHEBI:18405
Term: pyridoxal 5'-phosphate
Definition: The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
Chemical ID: MESH:D011732
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gad1decreases activityEXP 6480464CTDPyridoxal Phosphate results in decreased activity of GAD1 protein

PMID:7463050
Gad1affects bindingISORGD:7308536480464CTDPyridoxal Phosphate binds to GAD1 protein modified form

PMID:15686475
Gad1increases activityISORGD:106156480464CTDPyridoxal Phosphate results in increased activity of GAD1 protein

PMID:171340
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