Gad1 (glutamate decarboxylase 1) - Rat Genome Database

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Gene: Gad1 (glutamate decarboxylase 1) Ictidomys tridecemlineatus
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Symbol: Gad1
Name: glutamate decarboxylase 1
RGD ID: 12438410
Description: ENCODES a protein that exhibits glutamate binding (ortholog); glutamate decarboxylase activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN cellular response to hypoxia (ortholog); gamma-aminobutyric acid biosynthetic process (ortholog); locomotory exploration behavior (ortholog); PARTICIPATES IN 2-hydroxyglutaric aciduria pathway; beta-alanine metabolic pathway; Canavan disease pathway; ASSOCIATED WITH alcohol dependence (ortholog); amphetamine abuse (ortholog); anxiety disorder (ortholog); FOUND IN GABA-ergic synapse (ortholog); neuronal cell body (ortholog); perinuclear region of cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: glutamate decarboxylase 1, transcript variant X1; glutamate decarboxylase 1, transcript variant X2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303132,606,889 - 132,647,134 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365091,161,094 - 1,201,576 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365091,160,559 - 1,201,037 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Gad1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303132,606,889 - 132,647,134 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365091,161,094 - 1,201,576 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365091,160,559 - 1,201,037 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GAD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382170,813,210 - 170,861,151 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2170,813,213 - 170,861,151 (+)EnsemblGRCh38hg38GRCh38
GRCh372171,673,397 - 171,717,661 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362171,381,446 - 171,425,907 (+)NCBINCBI36Build 36hg18NCBI36
Build 342171,498,706 - 171,524,775NCBI
Celera2165,289,914 - 165,334,327 (+)NCBICelera
Cytogenetic Map2q31.1NCBI
HuRef2163,562,349 - 163,606,375 (+)NCBIHuRef
CHM1_12171,679,435 - 171,723,884 (+)NCBICHM1_1
T2T-CHM13v2.02171,290,353 - 171,338,262 (+)NCBIT2T-CHM13v2.0
Gad1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39270,392,109 - 70,432,358 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl270,383,416 - 70,432,358 (+)EnsemblGRCm39 Ensembl
GRCm38270,561,303 - 70,602,014 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl270,553,072 - 70,602,014 (+)EnsemblGRCm38mm10GRCm38
MGSCv37270,400,221 - 70,440,069 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36270,363,052 - 70,402,853 (+)NCBIMGSCv36mm8
Celera272,228,088 - 72,268,083 (+)NCBICelera
Cytogenetic Map2C2NCBI
cM Map241.63NCBI
Gad1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8375,777,260 - 75,818,099 (+)NCBIGRCr8
mRatBN7.2355,369,704 - 55,410,335 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl355,369,704 - 55,410,333 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx358,774,583 - 58,815,086 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0367,358,166 - 67,398,662 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0365,120,847 - 65,161,332 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0356,861,440 - 56,902,139 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl356,861,396 - 56,902,157 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0363,479,963 - 63,519,879 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4352,789,370 - 52,830,038 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1352,685,741 - 52,726,408 (+)NCBI
Celera354,926,942 - 54,967,478 (+)NCBICelera
Cytogenetic Map3q22NCBI
Gad1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554493,963,705 - 4,001,850 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554493,964,006 - 4,001,850 (-)NCBIChiLan1.0ChiLan1.0
GAD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21373,489,127 - 73,533,319 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B73,504,103 - 73,548,292 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B58,100,623 - 58,145,045 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B175,558,538 - 175,602,951 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B175,558,538 - 175,602,944 (+)Ensemblpanpan1.1panPan2
GAD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13615,351,289 - 15,391,701 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3615,349,683 - 15,391,824 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3615,364,114 - 15,403,437 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03615,474,678 - 15,516,842 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3615,474,925 - 15,516,838 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13615,565,032 - 15,604,314 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03615,552,796 - 15,592,193 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03615,664,544 - 15,703,870 (+)NCBIUU_Cfam_GSD_1.0
GAD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1576,991,928 - 77,034,812 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11576,991,863 - 77,034,819 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21586,375,113 - 86,419,237 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap15q21-q22NCBI
GAD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11056,351,495 - 56,396,476 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1056,353,253 - 56,396,524 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040143,149,876 - 143,195,107 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gad1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247878,308,759 - 8,347,686 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247878,308,759 - 8,345,929 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSSTOT00000003361   ⟹   ENSSTOP00000003008
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365091,161,094 - 1,201,576 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000030799   ⟹   ENSSTOP00000032480
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365091,161,205 - 1,185,208 (+)Ensembl
RefSeq Acc Id: XM_005324576   ⟹   XP_005324633
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303132,607,196 - 132,647,134 (+)NCBI
SpeTri2.0NW_0049365091,161,081 - 1,201,037 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021725912   ⟹   XP_021581587
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303132,606,889 - 132,647,134 (+)NCBI
SpeTri2.0NW_0049365091,160,559 - 1,201,037 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040294454   ⟹   XP_040150388
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303132,608,091 - 132,647,134 (+)NCBI
RefSeq Acc Id: XM_040294455   ⟹   XP_040150389
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303132,608,462 - 132,647,134 (+)NCBI
RefSeq Acc Id: XP_005324633   ⟸   XM_005324576
- UniProtKB: I3M255 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021581587   ⟸   XM_021725912
- UniProtKB: I3M255 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040150388   ⟸   XM_040294454
- UniProtKB: I3M255 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040150389   ⟸   XM_040294455
- UniProtKB: I3M255 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000003008   ⟸   ENSSTOT00000003361
RefSeq Acc Id: ENSSTOP00000032480   ⟸   ENSSTOT00000030799


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000003340 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000003361.3 UniProtKB/TrEMBL
  ENSSTOT00000030799.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.640.10 UniProtKB/TrEMBL
  3.90.1150.170 UniProtKB/TrEMBL
InterPro PyrdxlP-dep_de-COase UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase_major UniProtKB/TrEMBL
  Pyridoxal-P_BS UniProtKB/TrEMBL
NCBI Gene Gad1 ENTREZGENE
PANTHER GLUTAMATE DECARBOXYLASE 1 UniProtKB/TrEMBL
  GLUTAMATE DECARBOXYLASE-RELATED UniProtKB/TrEMBL
Pfam Pyridoxal_deC UniProtKB/TrEMBL
PROSITE DDC_GAD_HDC_YDC UniProtKB/TrEMBL
Superfamily-SCOP SSF53383 UniProtKB/TrEMBL
UniProt A0A287DG25_ICTTR UniProtKB/TrEMBL
  I3M255 ENTREZGENE, UniProtKB/TrEMBL