TP53 (tumor protein p53) - Rat Genome Database

Name: TP53
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: TP53 (tumor protein p53) Sus scrofa

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Symbol:

TP53

Name:

tumor protein p53

RGD ID:

14013963

Description:

ENCODES a protein that exhibits ATP binding (ortholog); chromatin binding (ortholog); cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of progesterone secretion; regulation of peptide hormone secretion; regulation of prostaglandin secretion; PARTICIPATES IN altered p53 signaling pathway; endometrial cancer pathway; non-small cell lung carcinoma pathway; ASSOCIATED WITH Acute Erythroleukemia (ortholog); acute kidney failure (ortholog); acute lymphoblastic leukemia (ortholog); FOUND IN nucleus; centrosome (ortholog); chromatin (ortholog); INTERACTS WITH alpha-mangostin; arsenous acid; bis(2-chloroethyl) sulfide

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

cellular tumor antigen p53; P53; tumor suppressor p53

Orthologs:

Homo sapiens (human) : TP53 (tumor protein p53) HGNC Alliance
Mus musculus (house mouse) : Trp53 (transformation related protein 53) MGI Alliance
Rattus norvegicus (Norway rat) : Tp53 (tumor protein p53) Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tp53 (tumor protein p53)
Pan paniscus (bonobo/pygmy chimpanzee) : TP53 (tumor protein p53)
Canis lupus familiaris (dog) : TP53 (tumor protein p53)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tp53 (tumor protein p53)
Chlorocebus sabaeus (African green monkey) : TP53 (tumor protein p53)
Heterocephalus glaber (naked mole-rat) : Tp53 (tumor protein p53)

more info ...

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TP53 (tumor protein p53)	HGNC	EggNOG, Ensembl, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Trp53 (transformation related protein 53)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Tp53 (tumor protein p53)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tp53 (tumor protein p53)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TP53 (tumor protein p53)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TP53 (tumor protein p53)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tp53 (tumor protein p53)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	TP53 (tumor protein p53)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tp53 (tumor protein p53)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	52,939,643 - 52,953,819 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	52,939,643 - 52,953,786 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	55,220,545 - 55,234,668 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3
Pig Cytomap	12	q12-q14	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation (Toggle Annotation Detail/Summary View)

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

RGD Manual Annotations

Imported Annotations - ClinVar