NCOA1 (nuclear receptor coactivator 1) - Rat Genome Database

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Gene: NCOA1 (nuclear receptor coactivator 1) Pan paniscus
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Symbol: NCOA1
Name: nuclear receptor coactivator 1
RGD ID: 11733908
Description: ENCODES a protein that exhibits nuclear estrogen receptor binding (ortholog); nuclear receptor binding (ortholog); nuclear retinoic acid receptor binding (ortholog); INVOLVED IN cellular response to hormone stimulus (ortholog); cellular response to Thyroglobulin triiodothyronine (ortholog); cerebellum development (ortholog); PARTICIPATES IN aldosterone signaling pathway; androgen signaling pathway; cortisol signaling pathway; ASSOCIATED WITH breast carcinoma (ortholog); Breast Neoplasms (ortholog); endometrial carcinoma (ortholog); FOUND IN RNA polymerase II transcription regulator complex (ortholog); transcription regulator complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212101,755,028 - 102,031,268 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A101,759,056 - 102,035,245 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A24,485,068 - 24,764,135 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A24,581,645 - 24,859,488 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A24,733,117 - 24,859,488 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NCOA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212101,755,028 - 102,031,268 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A101,759,056 - 102,035,245 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A24,485,068 - 24,764,135 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A24,581,645 - 24,859,488 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A24,733,117 - 24,859,488 (+)Ensemblpanpan1.1panPan2
NCOA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38224,491,254 - 24,770,702 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl224,491,254 - 24,770,702 (+)EnsemblGRCh38hg38GRCh38
GRCh37224,714,123 - 24,993,571 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36224,660,850 - 24,847,075 (+)NCBINCBI36Build 36hg18NCBI36
Build 34224,718,996 - 24,905,219NCBI
Celera224,648,250 - 24,833,882 (+)NCBICelera
Cytogenetic Map2p23.3NCBI
HuRef224,545,896 - 24,731,418 (+)NCBIHuRef
CHM1_1224,736,919 - 24,923,129 (+)NCBICHM1_1
T2T-CHM13v2.0224,525,913 - 24,805,480 (+)NCBIT2T-CHM13v2.0
Ncoa1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39124,297,362 - 4,569,452 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl124,297,362 - 4,527,182 (-)EnsemblGRCm39 Ensembl
GRCm38124,247,362 - 4,477,206 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl124,247,362 - 4,477,182 (-)EnsemblGRCm38mm10GRCm38
MGSCv37124,247,362 - 4,484,060 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36124,257,424 - 4,491,127 (-)NCBIMGSCv36mm8
Celera124,179,857 - 4,348,692 (-)NCBICelera
Cytogenetic Map12A1.1NCBI
cM Map122.05NCBI
Ncoa1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8632,952,090 - 33,229,829 (-)NCBIGRCr8
mRatBN7.2627,232,609 - 27,507,992 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl627,232,611 - 27,475,664 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx627,524,867 - 27,768,734 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0627,840,748 - 28,084,625 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0627,318,440 - 27,562,032 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0628,677,563 - 28,931,844 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl628,677,540 - 28,931,843 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0638,483,476 - 38,734,322 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4627,224,396 - 27,473,926 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1627,229,075 - 27,336,790 (-)NCBI
Celera626,704,021 - 26,946,167 (-)NCBICelera
Cytogenetic Map6q14NCBI
Ncoa1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554696,794,821 - 6,892,566 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554696,676,780 - 6,892,587 (+)NCBIChiLan1.0ChiLan1.0
NCOA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11718,880,676 - 19,124,300 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1718,880,383 - 19,122,258 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1718,777,980 - 19,021,230 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01719,302,445 - 19,397,682 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1719,153,592 - 19,396,341 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11718,890,805 - 19,134,195 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01718,899,937 - 19,143,634 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01718,940,197 - 19,183,703 (+)NCBIUU_Cfam_GSD_1.0
Ncoa1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629263,234,427 - 63,471,108 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364937,368,462 - 7,465,615 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364937,368,393 - 7,605,754 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NCOA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3113,999,253 - 114,250,298 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13113,997,214 - 114,251,080 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23121,230,135 - 121,286,004 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.23121,349,942 - 121,379,022 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NCOA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11482,898,368 - 83,028,137 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1482,897,348 - 83,013,589 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604528,994,261 - 29,270,072 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ncoa1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247386,943,726 - 7,054,454 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247386,770,745 - 7,054,616 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000061965   ⟹   ENSPPAP00000039056
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2A24,733,117 - 24,859,488 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000061972   ⟹   ENSPPAP00000039063
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2A24,747,745 - 24,859,488 (+)Ensembl
RefSeq Acc Id: XM_034952724   ⟹   XP_034808615
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v212101,755,028 - 101,929,105 (-)NCBI
NHGRI_mPanPan12A101,759,056 - 101,933,069 (-)NCBI
Mhudiblu_PPA_v02A24,587,223 - 24,762,072 (+)NCBI
RefSeq Acc Id: XM_034952725   ⟹   XP_034808616
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v212101,755,028 - 102,031,268 (-)NCBI
NHGRI_mPanPan12A101,759,056 - 102,035,245 (-)NCBI
Mhudiblu_PPA_v02A24,485,096 - 24,762,072 (+)NCBI
RefSeq Acc Id: XM_055108162   ⟹   XP_054964137
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v212101,755,028 - 101,929,105 (-)NCBI
NHGRI_mPanPan12A101,759,056 - 101,933,069 (-)NCBI
RefSeq Acc Id: XM_055108163   ⟹   XP_054964138
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v212101,757,315 - 101,929,105 (-)NCBI
NHGRI_mPanPan12A101,761,278 - 101,933,069 (-)NCBI
RefSeq Acc Id: XM_055108164   ⟹   XP_054964139
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v212101,757,264 - 101,929,105 (-)NCBI
NHGRI_mPanPan12A101,761,228 - 101,933,069 (-)NCBI
RefSeq Acc Id: XP_034808616   ⟸   XM_034952725
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CAU3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034808615   ⟸   XM_034952724
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CAU3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000039056   ⟸   ENSPPAT00000061965
RefSeq Acc Id: ENSPPAP00000039063   ⟸   ENSPPAT00000061972
RefSeq Acc Id: XP_054964137   ⟸   XM_055108162
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054964139   ⟸   XM_055108164
- Peptide Label: isoform X3
- UniProtKB: A0A2R9CDJ4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054964138   ⟸   XM_055108163
- Peptide Label: isoform X3
- UniProtKB: A0A2R9CDJ4 (UniProtKB/TrEMBL)
Protein Domains
bHLH   PAS


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000042202 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000061965.1 UniProtKB/TrEMBL
  ENSPPAT00000061972.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.280.10 UniProtKB/TrEMBL
  6.10.140.410 UniProtKB/TrEMBL
  PAS domain UniProtKB/TrEMBL
InterPro bHLH_dom UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/TrEMBL
  NCO_DUF1518 UniProtKB/TrEMBL
  NCOA1 UniProtKB/TrEMBL
  Nuc_rcpt_coact UniProtKB/TrEMBL
  Nuc_rcpt_coact_Ncoa-typ UniProtKB/TrEMBL
  Nuc_rcpt_coact_Ncoa_int_sf UniProtKB/TrEMBL
  Nuclear_rcpt_coactivator UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
  PAS-like_dom_sf UniProtKB/TrEMBL
  PAS_fold UniProtKB/TrEMBL
  SRC/p160_LXXLL UniProtKB/TrEMBL
NCBI Gene NCOA1 ENTREZGENE
PANTHER PTHR10684 UniProtKB/TrEMBL
  PTHR10684:SF1 UniProtKB/TrEMBL
Pfam DUF1518 UniProtKB/TrEMBL
  NCOA_u2 UniProtKB/TrEMBL
  Nuc_rec_co-act UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
  PAS_11 UniProtKB/TrEMBL
  SRC-1 UniProtKB/TrEMBL
PIRSF Nuclear_receptor_coactivator UniProtKB/TrEMBL
PROSITE BHLH UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
SMART DUF1518 UniProtKB/TrEMBL
  HLH UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
Superfamily-SCOP SSF47459 UniProtKB/TrEMBL
  SSF55785 UniProtKB/TrEMBL
  SSF69125 UniProtKB/TrEMBL
UniProt A0A2R9CAU3 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CDJ4 ENTREZGENE, UniProtKB/TrEMBL