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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:altered cell adhesion signaling pathway
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Accession:PW:0000671 term browser browse the term


show annotations for term's descendants           Sort by:
altered ephrin - ephrin receptor bidirectional signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Efna1 ephrin A1 ISS Present in gastrointestinal, liver and kidney cancers. RGD PMID:15561600 RGD:1304509 NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866 		JBrowse link
G Efna2 ephrin A2 ISS RGD PMID:15561600 RGD:1304509 NCBI chr 7:9,515,635...9,528,071
Ensembl chr 7:9,516,429...9,527,061 		JBrowse link
G Efna3 ephrin A3 ISS Present in neurobalstoma, neural cancers and leukemia. RGD PMID:15561600 RGD:1304509 NCBI chr 2:174,729,192...174,738,111
Ensembl chr 2:174,729,764...174,738,736 		JBrowse link
G Efnb1 ephrin B1 ISS Present in neuroblastoma, leukemia and lung cancer RGD PMID:15561600 RGD:1304509 NCBI chr  X:64,257,351...64,270,158
Ensembl chr  X:64,257,351...64,270,157 		JBrowse link
G Efnb3 ephrin B3 ISS Present in neuroblastomas and neural cancers RGD PMID:15561600 RGD:1304509 NCBI chr10:54,274,506...54,281,951
Ensembl chr10:54,274,506...54,280,471 		JBrowse link
G Epha3 Eph receptor A3 ISS Present in neuroblastomas, neural cancers, leukemias and lymphomas. RGD PMID:15561600 RGD:1304509 NCBI chr11:1,138,485...1,474,102
Ensembl chr11:1,140,985...1,473,900 		JBrowse link
G Epha7 Eph receptor A7 ISS RGD PMID:15561600 RGD:1304509 NCBI chr 5:42,975,353...43,128,703
Ensembl chr 5:42,975,405...43,127,112 		JBrowse link
altered integrin mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ilk integrin-linked kinase ISO RGD PMID:18772397 RGD:5490966 NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140 		JBrowse link
G Itga1 integrin subunit alpha 1 IMP RGD PMID:10536667 RGD:1302875 NCBI chr 2:46,646,125...46,812,237
Ensembl chr 2:46,653,193...46,812,238 		JBrowse link
G Itga11 integrin subunit alpha 11 ISO RGD PMID:18772397 RGD:5490966 NCBI chr 8:63,145,998...63,254,714
Ensembl chr 8:63,146,001...63,254,407 		JBrowse link
G Itga4 integrin subunit alpha 4 IMP
ISO		 RGD PMID:11782963 PMID:18772397 RGD:1302879, RGD:5490966 NCBI chr 3:64,162,764...64,235,010
Ensembl chr 3:64,163,085...64,233,715 		JBrowse link
G Itga5 integrin subunit alpha 5 ISS RGD PMID:10536667 RGD:1302875 NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837 		JBrowse link
G Itga8 integrin subunit alpha 8 ISO RGD PMID:9054500 RGD:40903006 NCBI chr17:75,304,004...75,501,510
Ensembl chr17:75,304,008...75,501,510 		JBrowse link
G Itga9 integrin subunit alpha 9 ISO RGD PMID:18772397 RGD:5490966 NCBI chr 8:118,307,424...118,615,527
Ensembl chr 8:118,307,381...118,613,754 		JBrowse link
G Itgb1 integrin subunit beta 1 ISS RGD PMID:9633916 RGD:1302874 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
altered Notch signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll1 delta like canonical Notch ligand 1 ISS paper on the human protein which may be involved in disease RGD PMID:10079256 RGD:1304492 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179 		JBrowse link
G Dll3 delta like canonical Notch ligand 3 ISS paper mentions mutations and diseases, deletion in mice RGD PMID:12141422 RGD:1304493 NCBI chr 1:83,562,011...83,570,008
Ensembl chr 1:83,562,014...83,569,750 		JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 ISS RGD PMID:12548545 RGD:1334460 NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312 		JBrowse link
G Jag1 jagged canonical Notch ligand 1 ISS RGD PMID:10964583 RGD:1304484 NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209 		JBrowse link
G Jag2 jagged canonical Notch ligand 2 ISS RGD PMID:10079256 RGD:1304492 NCBI chr 6:131,983,059...132,005,665
Ensembl chr 6:131,983,056...132,005,818 		JBrowse link
G Notch1 notch receptor 1 ISS RGD PMID:11900468 RGD:724389 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Notch4 notch receptor 4 ISS RGD PMID:10964583 RGD:1304484 NCBI chr20:4,160,362...4,184,466
Ensembl chr20:4,160,445...4,184,465 		JBrowse link
G Numb NUMB, endocytic adaptor protein ISS RGD PMID:15492044 RGD:1334451 NCBI chr 6:103,431,400...103,553,422
Ensembl chr 6:103,431,400...103,553,354 		JBrowse link
G Pofut1 protein O-fucosyltransferase 1 ISS RGD PMID:14570055 RGD:1334453 NCBI chr 3:141,708,618...141,735,558
Ensembl chr 3:141,708,644...141,734,786 		JBrowse link
altered Notch signaling pathway involving promoters term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 ISS RGD PMID:12548545 RGD:1334460 NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312 		JBrowse link
altered Notch signaling pathway involving the macromolecules modifying the main players term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Numb NUMB, endocytic adaptor protein ISS In humans, loss of Numb regulation over Notch is involved in breast cancer. RGD PMID:15492044 RGD:1334451 NCBI chr 6:103,431,400...103,553,422
Ensembl chr 6:103,431,400...103,553,354 		JBrowse link
G Pofut1 protein O-fucosyltransferase 1 ISS RGD PMID:14570055 RGD:1334453 NCBI chr 3:141,708,618...141,735,558
Ensembl chr 3:141,708,644...141,734,786 		JBrowse link
G Psen2 presenilin 2 ISO C. elegans transgenics expressing human wild-type and mutant PSEN2 RGD PMID:16474849 RGD:2302525 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174 		JBrowse link
altered Notch signaling pathway involving the main players term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll3 delta like canonical Notch ligand 3 ISS RGD PMID:12141422 RGD:1304493 NCBI chr 1:83,562,011...83,570,008
Ensembl chr 1:83,562,014...83,569,750 		JBrowse link
G Jag1 jagged canonical Notch ligand 1 ISS RGD PMID:15057910 RGD:1334443 NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209 		JBrowse link
G Notch1 notch receptor 1 ISS RGD PMID:15472075 RGD:1334450 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Notch3 notch receptor 3 ISS RGD PMID:14667809 RGD:1334442 NCBI chr 7:11,132,984...11,184,025
Ensembl chr 7:11,133,706...11,184,025 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6091
    signaling pathway 2634
      cell adhesion signaling pathway 413
        altered cell adhesion signaling pathway 26
          altered cell-cell signaling pathway + 18
          altered cell-extracellular matrix signaling pathway 0
          altered integrin mediated signaling pathway 8
paths to the root