Gene: Pofut1 (protein O-fucosyltransferase 1) Rattus norvegicus
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Symbol: Pofut1
Name: protein O-fucosyltransferase 1
Description: Predicted to have peptide-O-fucosyltransferase activity. Predicted to be involved in several processes, including circulatory system development; protein O-linked fucosylation; and regulation of Notch signaling pathway. Localizes to the endoplasmic reticulum. Human ortholog(s) of this gene implicated in Dowling-Degos disease. Orthologous to human POFUT1 (protein O-fucosyltransferase 1); PARTICIPATES IN altered Notch signaling pathway; altered Notch signaling pathway involving the macromolecules modifying the main players; Notch signaling pathway; INTERACTS WITH (RS)-amphetamine; 2,4,6-trinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Fut12; GDP-fucose protein O-fucosyltransferase 1; O-FucT-1; peptide-O-fucosyltransferase 1
Orthologs:
Homo sapiens (human) : POFUT1 (protein O-fucosyltransferase 1)  HGNC  Alliance
Mus musculus (house mouse) : Pofut1 (protein O-fucosyltransferase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pofut1 (protein O-fucosyltransferase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : POFUT1 (protein O-fucosyltransferase 1)
Canis lupus familiaris (dog) : POFUT1 (protein O-fucosyltransferase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pofut1 (protein O-fucosyltransferase 1)
Sus scrofa (pig) : POFUT1 (protein O-fucosyltransferase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03148,722,864 - 148,749,743 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03155,347,854 - 155,374,715 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43143,592,269 - 143,614,466 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13143,497,890 - 143,520,088 (+)NCBI
Celera3140,454,947 - 140,477,055 (+)NCBICelera
Cytogenetic Map3q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Pofut1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1303001
Created: 2004-12-03
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.