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ONTOLOGY REPORT - ANNOTATIONS

Term:nephron tubule formation
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Accession:GO:0072079 term browser browse the term
Definition:The developmental process pertaining to the initial formation of a nephron tubule from unspecified parts. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.


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nephron tubule formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1858008 (PMID:17537789)		 Ensembl
RGD		 PMID:17537789 GO_REF:0000107 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Wnt6 Wnt family member 6 acts_upstream_of_or_within ISO (PMID:11948913) RGD PMID:11948913 NCBI chr 9:83,778,552...83,792,186
Ensembl chr 9:76,329,882...76,343,523 		JBrowse link
mesonephric duct formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnf1b HNF1 homeobox B involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857856 (PMID:20040500)		 Ensembl
RGD		 PMID:20040500 GO_REF:0000107 NCBI chr10:69,233,377...69,287,360
Ensembl chr10:68,735,894...68,789,888 		JBrowse link
G Mir216a microRNA 216a involved_in ISO MGI:6361469 (PMID:31367007) RGD PMID:31367007 NCBI chr14:102,524,105...102,524,210
Ensembl chr14:102,524,105...102,524,210 		JBrowse link
G Mir216b microRNA 216b involved_in ISO MGI:6361477 (PMID:31367007) RGD PMID:31367007 NCBI chr14:102,513,054...102,513,155
Ensembl chr14:102,513,054...102,513,155 		JBrowse link
G Mir217 microRNA 217 involved_in ISO (PMID:31367007) RGD PMID:31367007 NCBI chr14:102,531,505...102,531,609
Ensembl chr14:102,531,505...102,531,609 		JBrowse link
G Wnt9b Wnt family member 9B acts_upstream_of_or_within ISO MGI:3526437 (PMID:16054034) RGD PMID:16054034 NCBI chr10:89,135,362...89,157,065
Ensembl chr10:88,635,331...88,657,035 		JBrowse link
mesonephric tubule formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax2 paired box 2 involved_in ISO (PMID:17300925) RGD PMID:17300925 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321 		JBrowse link
G Six1 SIX homeobox 1 involved_in ISO (PMID:17300925) RGD PMID:17300925 NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975 		JBrowse link
metanephric nephron tubule formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pax2 paired box 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17314325)		 UniProt
RGD		 PMID:17314325 GO_REF:0000024 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321 		JBrowse link
G Pax8 paired box 8 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17314325)		 UniProt
RGD		 PMID:17314325 GO_REF:0000024 NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363 		JBrowse link
G Sox8 SRY-box transcription factor 8 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:98371 (PMID:21212101)		 UniProt
RGD		 PMID:21212101 GO_REF:0000024 NCBI chr10:15,089,357...15,094,345
Ensembl chr10:14,584,829...14,589,818 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:98370 (PMID:21212101)		 UniProt
RGD		 PMID:21212101 GO_REF:0000024 NCBI chr10:98,305,744...98,311,250
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata3 GATA binding protein 3 involved_in ISO (PMID:19112489) RGD PMID:19112489 NCBI chr17:73,544,234...73,575,670
Ensembl chr17:68,643,873...68,665,391 		JBrowse link
negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata3 GATA binding protein 3 involved_in ISO (PMID:19112489) RGD PMID:19112489 NCBI chr17:73,544,234...73,575,670
Ensembl chr17:68,643,873...68,665,391 		JBrowse link
positive regulation of ureteric bud formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata3 GATA binding protein 3 involved_in ISO (PMID:19112489) RGD PMID:19112489 NCBI chr17:73,544,234...73,575,670
Ensembl chr17:68,643,873...68,665,391 		JBrowse link
G Gdnf glial cell derived neurotrophic factor involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:8657307)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:8657307 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Six1 SIX homeobox 1 involved_in ISO (PMID:17300925) RGD PMID:17300925 NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975 		JBrowse link
G Six4 SIX homeobox 4 involved_in ISO (PMID:17300925) RGD PMID:17300925 NCBI chr 6:91,802,328...91,816,002
Ensembl chr 6:91,802,329...91,815,992 		JBrowse link
regulation of ureteric bud formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gdnf glial cell derived neurotrophic factor involved_in IDA PMID:19112489 UniProt PMID:19112489 RGD:8656008 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
specification of anterior mesonephric tubule identity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Osr1 odd-skipped related transcription factor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:16790474)		 UniProt
RGD		 PMID:16790474 GO_REF:0000024 NCBI chr 6:32,369,561...32,380,822
Ensembl chr 6:32,373,816...32,380,817 		JBrowse link
specification of loop of Henle identity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hes5 hes family bHLH transcription factor 5 involved_in ISO (PMID:15821257) RGD PMID:15821257 NCBI chr 5:170,804,511...170,807,988
Ensembl chr 5:165,522,234...165,523,001 		JBrowse link
G Irx1 iroquois homeobox 1 involved_in ISO (PMID:17875669) RGD PMID:17875669 NCBI chr 1:31,294,615...31,300,444
Ensembl chr 1:31,294,615...31,300,444 		JBrowse link
G Irx2 iroquois homeobox 2 involved_in ISO (PMID:17875669) RGD PMID:17875669 NCBI chr 1:30,660,960...30,666,378
Ensembl chr 1:30,660,960...30,666,378 		JBrowse link
G Irx3 iroquois homeobox 3 involved_in ISO (PMID:17875669) RGD PMID:17875669 NCBI chr19:15,211,882...15,215,317
Ensembl chr19:15,211,878...15,215,317 		JBrowse link
specification of posterior mesonephric tubule identity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Osr1 odd-skipped related transcription factor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:16790474)		 UniProt
RGD		 PMID:16790474 GO_REF:0000024 NCBI chr 6:32,369,561...32,380,822
Ensembl chr 6:32,373,816...32,380,817 		JBrowse link
ureteric bud formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata3 GATA binding protein 3 involved_in ISO (PMID:16319112) RGD PMID:16319112 NCBI chr17:73,544,234...73,575,670
Ensembl chr17:68,643,873...68,665,391 		JBrowse link
G Gdnf glial cell derived neurotrophic factor involved_in IEA
ISO		 GO_REF:0000107
(PMID:8657307)		 Ensembl
RGD		 PMID:8657307 GO_REF:0000107 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:17522159) RGD PMID:17522159 NCBI chr 3:120,966,639...120,978,319
Ensembl chr 3:100,512,313...100,524,082 		JBrowse link
G Hs2st1 heparan sulfate 2-O-sulfotransferase 1 acts_upstream_of_or_within ISO MGI:1934916 (PMID:9637690) RGD PMID:9637690 NCBI chr 2:236,168,391...236,302,186
Ensembl chr 2:233,508,021...233,641,769 		JBrowse link
G Nog noggin involved_in IEA
ISO		 GO_REF:0000107
(PMID:17522159)		 Ensembl
RGD		 PMID:17522159 GO_REF:0000107 NCBI chr10:74,625,874...74,627,501
Ensembl chr10:74,128,712...74,130,339 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20553
    developmental process 7140
      anatomical structure morphogenesis 3013
        embryonic morphogenesis 709
          morphogenesis of embryonic epithelium 185
            embryonic epithelial tube formation 154
              nephron tubule formation 23
                mesonephric tubule formation + 14
                metanephric nephron tubule formation + 4
                pronephric nephron tubule formation 0
                specification of nephron tubule identity + 5
Path 2
Term Annotations click to browse term
  biological_process 20553
    developmental process 7140
      anatomical structure development 6638
        multicellular organism development 5350
          system development 4630
            renal system development 423
              kidney development 409
                nephron development 192
                  nephron epithelium development 143
                    nephron tubule development 120
                      nephron tubule morphogenesis 92
                        nephron tubule formation 23
                          mesonephric tubule formation + 14
                          metanephric nephron tubule formation + 4
                          pronephric nephron tubule formation 0
                          specification of nephron tubule identity + 5
paths to the root