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Gene: Irx1 (iroquois homeobox 1) Rattus norvegicus
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Symbol: Irx1
Name: iroquois homeobox 1
Description: Predicted to have sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; proximal/distal pattern formation involved in metanephric nephron development; and specification of loop of Henle identity. Predicted to localize to the nucleus. Orthologous to human IRX1 (iroquois homeobox 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Iroquois related homeobox 1; Iroquois related homeobox 1 (Drosophila) ; iroquois-class homeodomain protein IRX-1; LOC306659
Orthologs:
Homo sapiens (human) : IRX1 (iroquois homeobox 1)  HGNC  Alliance
Mus musculus (house mouse) : Irx1 (Iroquois homeobox 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Irx1 (iroquois homeobox 1)
Pan paniscus (bonobo/pygmy chimpanzee) : IRX1 (iroquois homeobox 1)
Canis lupus familiaris (dog) : IRX1 (iroquois homeobox 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Irx1 (iroquois homeobox 1)
Sus scrofa (pig) : IRX1 (iroquois homeobox 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0133,910,912 - 33,916,741 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0135,319,895 - 35,325,724 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4171,390,894 - 1,396,724 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1171,391,104 - 1,396,424 (+)NCBI
Celera129,929,767 - 29,935,596 (+)NCBICelera
Cytogenetic Map1p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Irx1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309060
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.