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ONTOLOGY REPORT - ANNOTATIONS

Term:immunoglobulin mediated immune response
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Accession:GO:0016064 term browser browse the term
Definition:An immune response mediated by immunoglobulins, whether cell-bound or in solution.
Synonyms:exact_synonym: antibody-mediated immune response

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show annotations for term's descendants           Sort by:
immunoglobulin mediated immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl10 BCL10 immune signaling adaptor acts_upstream_of_or_within ISO (PMID:11163238) MGI PMID:11163238 NCBI chrNW_004624742:12,210,333...12,222,533
Ensembl chrNW_004624742:12,210,360...12,221,759 		JBrowse link
G Card9 caspase recruitment domain family member 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624760:1,533,247...1,542,529
Ensembl chrNW_004624760:1,533,390...1,540,162 		JBrowse link
G Cd19 CD19 molecule involved_in ISO (PMID:16672701) UniProt PMID:16672701 NCBI chrNW_004624782:12,844,148...12,850,770
Ensembl chrNW_004624782:12,845,432...12,850,576 		JBrowse link
G Cd74 CD74 molecule acts_upstream_of_or_within ISO (PMID:7679955) MGI PMID:7679955 NCBI chrNW_004624774:9,699,876...9,708,871
Ensembl chrNW_004624774:9,700,393...9,709,514 		JBrowse link
G Cfh complement factor H acts_upstream_of_or_within ISO (PMID:19828624) MGI PMID:19828624 NCBI chrNW_004624798:3,332,549...3,414,435 JBrowse link
G Cr2 complement C3d receptor 2 acts_upstream_of_or_within ISO (PMID:19828624) MGI PMID:19828624 NCBI chrNW_004624807:4,149,472...4,179,269
Ensembl chrNW_004624807:4,152,230...4,179,211 		JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig acts_upstream_of_or_within ISO (PMID:10395649), (PMID:14643301) MGI PMID:10395649 PMID:14643301 NCBI chrNW_004624794:168,564...172,433
Ensembl chrNW_004624794:168,564...172,034 		JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb acts_upstream_of_or_within ISO (PMID:10395649), (PMID:14643301) MGI PMID:10395649 PMID:14643301 NCBI chrNW_004624826:97,605...112,101 JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15944273) Ensembl
MGI		 PMID:15944273 GO_REF:0000107 NCBI chrNW_004624940:825,368...842,268
Ensembl chrNW_004624940:819,854...842,284 		JBrowse link
G Il4r interleukin 4 receptor acts_upstream_of_or_within ISO (PMID:15944273) MGI PMID:15944273 NCBI chrNW_004624782:11,981,781...12,008,362 JBrowse link
G Il9 interleukin 9 acts_upstream_of_or_within ISO (PMID:30082831) MGI PMID:30082831 NCBI chrNW_004624733:11,226,769...11,229,461
Ensembl chrNW_004624733:11,226,769...11,229,461 		JBrowse link
G Il9r interleukin 9 receptor acts_upstream_of_or_within ISO (PMID:30082831) MGI PMID:30082831 NCBI chrNW_004624913:906,953...918,906
Ensembl chrNW_004624913:908,644...920,658 		JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D acts_upstream_of_or_within ISO (PMID:10704460) MGI PMID:10704460 NCBI chrNW_004624843:5,685,409...5,774,459
Ensembl chrNW_004624843:5,685,502...5,773,469 		JBrowse link
G Irf7 interferon regulatory factor 7 acts_upstream_of_or_within ISO (PMID:15800576) MGI PMID:15800576 NCBI chrNW_004624766:21,850,211...21,853,189 JBrowse link
G LOC101700274 HLA class II histocompatibility antigen, DM alpha chain acts_upstream_of_or_within ISO (PMID:11714799) MGI PMID:11714799 NCBI chrNW_004624754:23,752,352...23,765,319
Ensembl chrNW_004624754:23,762,051...23,765,593 		JBrowse link
G LOC101706353 HLA class II histocompatibility antigen, DR alpha chain acts_upstream_of_or_within ISO (PMID:11714799) MGI PMID:11714799 NCBI chrNW_004624754:24,079,459...24,086,342
Ensembl chrNW_004624754:24,079,366...24,084,512 		JBrowse link
G Myd88 MYD88 innate immune signal transduction adaptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15800576) Ensembl
MGI		 PMID:15800576 GO_REF:0000107 NCBI chrNW_004624731:2,677,259...2,681,408
Ensembl chrNW_004624731:2,677,290...2,681,489 		JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (PMID:25124037) MGI PMID:25124037 NCBI chrNW_004624789:15,612,311...15,623,878
Ensembl chrNW_004624789:15,612,335...15,624,152 		JBrowse link
G Prkcd protein kinase C delta acts_upstream_of_or_within ISO (PMID:11976687) MGI PMID:11976687 NCBI chrNW_004624822:4,035,819...4,062,907
Ensembl chrNW_004624822:4,033,130...4,059,555 		JBrowse link
G Tcirg1 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16542376) Ensembl
MGI		 PMID:16542376 GO_REF:0000107 NCBI chrNW_004624767:18,809,626...18,820,360
Ensembl chrNW_004624767:18,809,689...18,820,390 		JBrowse link
G Tlr4 toll like receptor 4 ISO RGD PMID:19257980 RGD:2312508 NCBI chrNW_004624760:17,596,516...17,608,955
Ensembl chrNW_004624760:17,598,630...17,609,120 		JBrowse link
G Tnfsf13 TNF superfamily member 13 acts_upstream_of_or_within ISO (PMID:14988498) MGI PMID:14988498 NCBI chrNW_004624786:10,175,534...10,179,233
Ensembl chrNW_004624786:10,175,859...10,179,233 		JBrowse link
antibody-dependent cellular cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcgr3a Fc fragment of IgG receptor IIIa involved_in ISO (PMID:11711607), (PMID:27670158), (PMID:28652325) UniProt PMID:11711607 PMID:27670158 PMID:28652325 NCBI chrNW_004624826:51,387...59,117 JBrowse link
B cell affinity maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7680896) Ensembl
MGI		 PMID:7680896 GO_REF:0000107 NCBI chrNW_004624902:1,173,101...1,216,662
Ensembl chrNW_004624902:1,182,682...1,216,171 		JBrowse link
G LOC101703821 HLA class II histocompatibility antigen, DQ beta 1 chain involved_in ISO (MGI:4943414|PMID:1378867) BHF-UCL PMID:1378867 MGI:4943414 NCBI chrNW_004624754:23,895,509...23,902,487
Ensembl chrNW_004624754:23,895,607...23,906,713 		JBrowse link
G Traf3ip2 TRAF3 interacting protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624933:507,879...558,357
Ensembl chrNW_004624933:506,254...554,015 		JBrowse link
complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qa complement C1q A chain involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11901193) Ensembl
MGI		 PMID:11901193 GO_REF:0000107 NCBI chrNW_004624764:7,363,615...7,366,408
Ensembl chrNW_004624764:7,363,567...7,366,617 		JBrowse link
G C1qb complement C1q B chain involved_in ISO (PMID:29449492) ComplexPortal PMID:29449492 NCBI chrNW_004624764:7,377,013...7,382,953
Ensembl chrNW_004624764:7,376,967...7,383,445 		JBrowse link
G C1qc complement C1q C chain involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624764:7,369,365...7,373,238
Ensembl chrNW_004624764:7,369,338...7,373,436 		JBrowse link
G C1r complement C1r involved_in IEA UniProt GO_REF:0000043 NCBI chrNW_004624860:3,675,926...3,684,598
Ensembl chrNW_004624860:3,676,252...3,684,406 		JBrowse link
G C2 complement C2 involved_in IEA UniProt GO_REF:0000043 NCBI chrNW_004624754:24,316,778...24,327,065
Ensembl chrNW_004624754:24,317,058...24,322,656 		JBrowse link
G C3 complement C3 involved_in IEA UniProt GO_REF:0000043 NCBI chrNW_004624828:3,773,816...3,798,077
Ensembl chrNW_004624828:3,770,221...3,797,946 		JBrowse link
G C6 complement C6 involved_in IEA UniProt GO_REF:0000043 NCBI chrNW_004624759:13,775,339...13,842,415
Ensembl chrNW_004624759:13,775,358...13,842,648 		JBrowse link
G C7 complement C7 involved_in IEA UniProt GO_REF:0000043 NCBI chrNW_004624759:13,991,104...14,114,271
Ensembl chrNW_004624759:13,992,681...14,114,411 		JBrowse link
G C8a complement C8 alpha chain involved_in IEA UniProt GO_REF:0000043 NCBI chrNW_004624862:3,234,826...3,288,574
Ensembl chrNW_004624862:3,232,463...3,288,640 		JBrowse link
G C8b complement C8 beta chain involved_in IEA UniProt GO_REF:0000043 NCBI chrNW_004624862:3,187,573...3,224,895
Ensembl chrNW_004624862:3,187,120...3,225,751 		JBrowse link
G C9 complement C9 involved_in IEA UniProt GO_REF:0000043 NCBI chrNW_004624759:15,534,743...15,623,767
Ensembl chrNW_004624759:15,534,660...15,624,381 		JBrowse link
G Crp C-reactive protein ISO RGD PMID:16367929 RGD:1580273 NCBI chrNW_004624794:1,531,555...1,533,804
Ensembl chrNW_004624794:1,531,571...1,533,804 		JBrowse link
G LOC101710435 complement C5 involved_in IEA UniProt GO_REF:0000043 NCBI chrNW_004624760:14,296,904...14,396,585
Ensembl chrNW_004624760:14,296,967...14,396,188 		JBrowse link
G LOC101716245 mannose-binding protein A-like involved_in IEA UniProt GO_REF:0000043 NCBI chrNW_004624841:6,895,594...6,899,930 JBrowse link
G LOC101719002 complement C4-A involved_in IEA UniProt GO_REF:0000043 NCBI chrNW_004624754:24,258,026...24,270,710 JBrowse link
G Mbl2 mannose binding lectin 2 involved_in IEA UniProt GO_REF:0000043 NCBI chrNW_004624791:10,881,319...10,886,294
Ensembl chrNW_004624791:10,881,268...10,886,297 		JBrowse link
humoral immune response mediated by circulating immunoglobulin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl3 BCL3 transcription coactivator acts_upstream_of_or_within ISO (PMID:9009202) MGI PMID:9009202 NCBI chrNW_004624907:1,656,803...1,666,774
Ensembl chrNW_004624907:1,656,783...1,667,575 		JBrowse link
G Cd81 CD81 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624767:15,192,446...15,210,923
Ensembl chrNW_004624767:15,192,452...15,210,922 		JBrowse link
G Exo1 exonuclease 1 acts_upstream_of_or_within ISO (PMID:14716311) MGI PMID:14716311 NCBI chrNW_004624771:12,215,957...12,230,908 JBrowse link
G Fcmr Fc mu receptor involved_in ISO (MGI:5448091|PMID:22988094) UniProt PMID:22988094 MGI:5448091 NCBI chrNW_004624807:4,567,240...4,581,406 JBrowse link
G Zp2 zona pellucida glycoprotein 2 involved_in ISO (PMID:12052239) UniProt PMID:12052239 NCBI chrNW_004624782:7,275,156...7,287,480
Ensembl chrNW_004624782:7,275,207...7,287,114 		JBrowse link
G Zp3 zona pellucida glycoprotein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624740:15,037,818...15,044,207
Ensembl chrNW_004624740:15,037,943...15,044,193 		JBrowse link
immune complex formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO (PMID:25848017) MGI PMID:25848017 NCBI chrNW_004624730:2,431,270...2,433,010
Ensembl chrNW_004624730:2,431,999...2,432,959 		JBrowse link
isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation induced cytidine deaminase involved_in
acts_upstream_of_or_within		 ISO (MGI:5004983|PMID:21518874)
(PMID:17713479)		 UniProt
MGI		 PMID:17713479 PMID:21518874 MGI:5004983 NCBI chrNW_004624860:4,912,938...4,927,846
Ensembl chrNW_004624860:4,912,656...4,926,634 		JBrowse link
G Atad5 ATPase family AAA domain containing 5 acts_upstream_of ISO (PMID:25404367) MGI PMID:25404367 NCBI chrNW_004624875:97,048...154,420
Ensembl chrNW_004624875:97,670...151,080 		JBrowse link
G Batf basic leucine zipper ATF-like transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624734:26,118,840...26,139,328
Ensembl chrNW_004624734:26,118,754...26,139,468 		JBrowse link
G Cd40lg CD40 ligand involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624808:10,472,028...10,484,407
Ensembl chrNW_004624808:10,472,572...10,484,338 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit acts_upstream_of_or_within ISO (PMID:15280420) MGI PMID:15280420 NCBI chrNW_004624907:2,288,380...2,298,909
Ensembl chrNW_004624907:2,288,423...2,298,373 		JBrowse link
G Exo1 exonuclease 1 acts_upstream_of_or_within ISO (PMID:14716311) MGI PMID:14716311 NCBI chrNW_004624771:12,215,957...12,230,908 JBrowse link
G Exosc3 exosome component 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624930:1,393,087...1,403,483
Ensembl chrNW_004624930:1,393,087...1,398,347 		JBrowse link
G Exosc6 exosome component 6 involved_in ISO (MGI:5009766|PMID:21255825) UniProt PMID:21255825 MGI:5009766 NCBI chrNW_004624746:12,538,315...12,539,678
Ensembl chrNW_004624746:12,538,775...12,539,593 		JBrowse link
G Lig4 DNA ligase 4 acts_upstream_of_or_within ISO (PMID:17713479) MGI PMID:17713479 NCBI chrNW_004624793:3,699,394...3,706,591
Ensembl chrNW_004624793:3,699,506...3,706,073 		JBrowse link
G Mlh1 mutL homolog 1 acts_upstream_of_or_within ISO (PMID:12743174) MGI PMID:12743174 NCBI chrNW_004624788:15,110,436...15,160,462
Ensembl chrNW_004624788:15,110,658...15,160,535 		JBrowse link
G Msh2 mutS homolog 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12743174)
(PMID:10430621)		 Ensembl
MGI		 PMID:10430621 PMID:12743174 GO_REF:0000107 NCBI chrNW_004624738:28,780,596...28,861,523
Ensembl chrNW_004624738:28,780,614...28,861,704 		JBrowse link
G Msh6 mutS homolog 6 acts_upstream_of_or_within ISO (PMID:17015724)
(PMID:16618598)		 MGI PMID:16618598 PMID:17015724 NCBI chrNW_004624738:29,083,696...29,108,792
Ensembl chrNW_004624738:29,083,692...29,108,792 		JBrowse link
G Nbn nibrin involved_in ISO (MGI:3529405|PMID:15668383) UniProt PMID:15668383 MGI:3529405 NCBI chrNW_004624744:2,013,936...2,061,726
Ensembl chrNW_004624744:2,013,922...2,061,708 		JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (PMID:25124037)
(PMID:31182790)		 MGI PMID:25124037 PMID:31182790 NCBI chrNW_004624789:15,612,311...15,623,878
Ensembl chrNW_004624789:15,612,335...15,624,152 		JBrowse link
G Rnf168 ring finger protein 168 involved_in ISO (MGI:4420833|PMID:20080757) UniProt PMID:20080757 MGI:4420833 NCBI chrNW_004624730:61,592,967...61,627,585
Ensembl chrNW_004624730:61,591,943...61,627,170 		JBrowse link
G Rnf8 ring finger protein 8 involved_in ISO (MGI:4420833|PMID:20080757) UniProt PMID:20080757 MGI:4420833 NCBI chrNW_004624754:20,683,133...20,714,469
Ensembl chrNW_004624754:20,679,867...20,714,522 		JBrowse link
G Sanbr SANT and BTB domain regulator of CSR involved_in ISO (MGI:6707280|PMID:33831416) UniProt PMID:33831416 MGI:6707280 NCBI chrNW_004624833:772,761...828,302
Ensembl chrNW_004624833:771,627...825,815 		JBrowse link
G Swap70 switching B cell complex subunit SWAP70 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9642267) Ensembl
MGI		 PMID:9642267 GO_REF:0000107 NCBI chrNW_004624766:1,794,430...1,887,927
Ensembl chrNW_004624766:1,794,530...1,885,472 		JBrowse link
G Ung uracil DNA glycosylase acts_upstream_of_or_within ISO (PMID:17015724) MGI PMID:17015724 NCBI chrNW_004624747:12,261,546...12,275,229
Ensembl chrNW_004624747:12,261,623...12,274,859 		JBrowse link
G Xrcc4 X-ray repair cross complementing 4 acts_upstream_of_or_within ISO (PMID:17713479) MGI PMID:17713479 NCBI chrNW_004624743:3,299,329...3,549,182
Ensembl chrNW_004624743:3,317,351...3,552,161 		JBrowse link
isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr6 C-C motif chemokine receptor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624785:12,190,802...12,203,924 JBrowse link
isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6 transcription repressor acts_upstream_of ISO (PMID:10490661) MGI PMID:10490661 NCBI chrNW_004624730:69,145,035...69,167,583
Ensembl chrNW_004624730:69,154,080...69,167,689 		JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of ISO (PMID:16275384) MGI PMID:16275384 NCBI chrNW_004624893:995,145...1,008,492
Ensembl chrNW_004624893:995,182...1,008,679 		JBrowse link
G Il4 interleukin 4 acts_upstream_of ISO (PMID:14988498) MGI PMID:14988498 NCBI chrNW_004624733:39,412,800...39,420,079 JBrowse link
G Stat6 signal transducer and activator of transcription 6 acts_upstream_of ISO (PMID:10490661) MGI PMID:10490661 NCBI chrNW_004624802:10,809,234...10,847,762
Ensembl chrNW_004624802:10,809,252...10,846,693 		JBrowse link
isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in ISO (PMID:16148103) BHF-UCL PMID:16148103 NCBI chrNW_004624889:2,736,727...2,746,333 JBrowse link
G Il4 interleukin 4 acts_upstream_of ISO (PMID:14988498) MGI PMID:14988498 NCBI chrNW_004624733:39,412,800...39,420,079 JBrowse link
negative regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoh apolipoprotein H involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624870:2,082,050...2,096,220
Ensembl chrNW_004624870:2,081,968...2,099,517 		JBrowse link
G C4bpb complement component 4 binding protein beta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624807:4,407,008...4,416,313
Ensembl chrNW_004624807:4,406,766...4,415,248 		JBrowse link
G Cd46 CD46 molecule involved_in ISO (PMID:9029106) AgBase PMID:9029106 NCBI chrNW_004624807:4,040,639...4,074,631 JBrowse link
G LOC101721321 C4b-binding protein alpha chain involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624807:4,371,116...4,403,425
Ensembl chrNW_004624807:4,370,969...4,401,458 		JBrowse link
G Susd4 sushi domain containing 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624835:5,531,507...5,600,181
Ensembl chrNW_004624835:5,531,472...5,599,922 		JBrowse link
negative regulation of humoral immune response mediated by circulating immunoglobulin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcgr2b Fc fragment of IgG receptor IIb acts_upstream_of_or_within ISO (PMID:12385742) MGI PMID:12385742 NCBI chrNW_004624826:97,605...112,101 JBrowse link
G Foxj1 forkhead box J1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624801:6,025,756...6,030,487
Ensembl chrNW_004624801:6,025,793...6,030,486 		JBrowse link
G Ptpn6 protein tyrosine phosphatase non-receptor type 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9254656) Ensembl
MGI		 PMID:9254656 GO_REF:0000107 NCBI chrNW_004624860:3,580,225...3,595,403
Ensembl chrNW_004624860:3,580,560...3,595,090 		JBrowse link
negative regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Parp3 poly(ADP-ribose) polymerase family member 3 involved_in ISO (MGI:6214451|PMID:26000965) UniProt PMID:26000965 MGI:6214451 NCBI chrNW_004624730:5,761,635...5,768,138
Ensembl chrNW_004624730:5,762,148...5,769,094 		JBrowse link
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6 transcription repressor acts_upstream_of_or_within ISO (PMID:10490661) MGI PMID:10490661 NCBI chrNW_004624730:69,145,035...69,167,583
Ensembl chrNW_004624730:69,154,080...69,167,689 		JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO (PMID:16275384) MGI PMID:16275384 NCBI chrNW_004624893:995,145...1,008,492
Ensembl chrNW_004624893:995,182...1,008,679 		JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within ISO (PMID:17137798) MGI PMID:17137798 NCBI chrNW_004624774:1,245,587...1,353,253
Ensembl chrNW_004624774:1,303,773...1,353,253 		JBrowse link
negative regulation of type I hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcgr2b Fc fragment of IgG receptor IIb acts_upstream_of_or_within ISO (PMID:8552190) MGI PMID:8552190 NCBI chrNW_004624826:97,605...112,101 JBrowse link
positive regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6275756|PMID:30548312) ARUK-UCL PMID:30548312 MGI:6275756 NCBI chrNW_004624754:17,643,397...17,649,255
Ensembl chrNW_004624754:17,643,363...17,648,231 		JBrowse link
positive regulation of humoral immune response mediated by circulating immunoglobulin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer2 Fc fragment of IgE receptor II acts_upstream_of_or_within ISO (PMID:8041705) MGI PMID:8041705 NCBI chrNW_004624828:747,800...754,185
Ensembl chrNW_004624828:748,671...754,185 		JBrowse link
G Hpx hemopexin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18641331) Ensembl
MGI		 PMID:18641331 GO_REF:0000107 NCBI chrNW_004624817:7,947,554...7,957,553
Ensembl chrNW_004624817:7,947,639...7,957,462 		JBrowse link
G Lta lymphotoxin alpha acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:9834074) MGI
Ensembl		 PMID:9834074 GO_REF:0000107 NCBI chrNW_004624754:24,626,930...24,628,412
Ensembl chrNW_004624754:24,627,318...24,628,182 		JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:15692051) MGI PMID:15692051 NCBI chrNW_004624757:5,956,873...6,000,052
Ensembl chrNW_004624757:5,958,486...6,000,103 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of_or_within ISO (PMID:8566034) MGI PMID:8566034 NCBI chrNW_004624798:1,700,732...1,814,603
Ensembl chrNW_004624798:1,699,541...1,814,656 		JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO (PMID:9834074) MGI PMID:9834074 NCBI chrNW_004624754:24,623,059...24,625,647
Ensembl chrNW_004624754:24,623,425...24,625,531 		JBrowse link
positive regulation of immunoglobulin mediated immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd226 CD226 molecule involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624806:11,324,239...11,390,487
Ensembl chrNW_004624806:11,324,344...11,388,206 		JBrowse link
G LOC101712173 poliovirus receptor homolog involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624907:1,582,636...1,596,528 JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624907:1,713,786...1,739,158
Ensembl chrNW_004624907:1,713,443...1,740,627 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:3763508|PMID:12496423) BHF-UCL PMID:12496423 MGI:3763508 NCBI chrNW_004624771:8,580,489...8,599,735 JBrowse link
positive regulation of immunoglobulin production in mucosal tissue term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CUNH17orf99 chromosome unknown C17orf99 homolog involved_in ISO (MGI:6103709|PMID:28978694) UniProt PMID:28978694 MGI:6103709 NCBI chrNW_004624801:7,668,551...7,678,531 JBrowse link
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:3763508|PMID:12496423) BHF-UCL PMID:12496423 MGI:3763508 NCBI chrNW_004624771:8,580,489...8,599,735 JBrowse link
positive regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Exosc3 exosome component 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21255825) Ensembl
MGI		 PMID:21255825 GO_REF:0000107 NCBI chrNW_004624930:1,393,087...1,403,483
Ensembl chrNW_004624930:1,393,087...1,398,347 		JBrowse link
G Exosc6 exosome component 6 acts_upstream_of_or_within ISO (PMID:21255825) MGI PMID:21255825 NCBI chrNW_004624746:12,538,315...12,539,678
Ensembl chrNW_004624746:12,538,775...12,539,593 		JBrowse link
G Hmces 5-hydroxymethylcytosine binding, ES cell specific involved_in ISO (MGI:6393148|PMID:31806351) UniProt PMID:31806351 MGI:6393148 NCBI chrNW_004624872:344,249...353,577
Ensembl chrNW_004624872:344,262...352,936 		JBrowse link
G Kmt5b lysine methyltransferase 5B involved_in ISO (MGI:6370097|PMID:28114273) UniProt PMID:28114273 MGI:6370097 NCBI chrNW_004624767:18,654,682...18,716,087
Ensembl chrNW_004624767:18,655,193...18,716,252 		JBrowse link
G Kmt5c lysine methyltransferase 5C involved_in ISO (MGI:6370097|PMID:28114273) UniProt PMID:28114273 MGI:6370097 NCBI chrNW_004624832:1,945,194...1,951,016
Ensembl chrNW_004624832:1,945,193...1,951,247 		JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624818:1,274,553...1,286,750
Ensembl chrNW_004624818:1,282,082...1,286,997 		JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (MGI:4821506|PMID:20671152) UniProt PMID:20671152 MGI:4821506 NCBI chrNW_004624800:2,653,381...2,709,261
Ensembl chrNW_004624800:2,653,732...2,707,161 		JBrowse link
G Rif1 replication timing regulatory factor 1 involved_in ISO (MGI:5468036|PMID:23306439), (MGI:5476381|PMID:23333305), (MGI:5490831|PMID:23333306) UniProt PMID:23306439 PMID:23333305 PMID:23333306 MGI:5468036 MGI:5476381 MGI:5490831 NCBI chrNW_004624866:5,619,758...5,680,165 JBrowse link
G Shld1 shieldin complex subunit 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624741:6,630,746...6,766,314
Ensembl chrNW_004624741:6,638,889...6,721,118 		JBrowse link
G Shld2 shieldin complex subunit 2 involved_in ISO (PMID:29656893) UniProt PMID:29656893 NCBI chrNW_004624841:21,077...133,155
Ensembl chrNW_004624841:20,431...133,163 		JBrowse link
G Tfrc transferrin receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624730:61,282,650...61,313,487
Ensembl chrNW_004624730:61,285,334...61,313,550 		JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 involved_in ISO (MGI:3041657|PMID:15077110), (MGI:3046005|PMID:15159415)
(PMID:23345425)
(PMID:23760478)		 UniProt PMID:15077110 PMID:15159415 PMID:23345425 PMID:23760478 MGI:3041657 MGI:3046005 NCBI chrNW_004624804:10,517,531...10,612,238
Ensembl chrNW_004624804:10,517,696...10,591,688 		JBrowse link
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chrNW_004624788:15,110,436...15,160,462
Ensembl chrNW_004624788:15,110,658...15,160,535 		JBrowse link
G Msh2 mutS homolog 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624738:28,780,596...28,861,523
Ensembl chrNW_004624738:28,780,614...28,861,704 		JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 acts_upstream_of_or_within ISO (PMID:23241889) MGI PMID:23241889 NCBI chrNW_004624755:25,510,329...25,588,540
Ensembl chrNW_004624755:25,509,301...25,588,204 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chrNW_004624740:31,315,121...31,345,137 JBrowse link
G Tgfb1 transforming growth factor beta 1 acts_upstream_of_or_within
involved_in		 ISO
IEA
ISS		 (PMID:14988498) MGI
Ensembl
AgBase		 PMID:14988498 GO_REF:0000024 GO_REF:0000107 NCBI chrNW_004624907:162,567...175,696
Ensembl chrNW_004624907:161,569...176,605 		JBrowse link
G Tnfsf13 TNF superfamily member 13 acts_upstream_of_or_within ISO (PMID:14988498) MGI PMID:14988498 NCBI chrNW_004624786:10,175,534...10,179,233
Ensembl chrNW_004624786:10,175,859...10,179,233 		JBrowse link
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcf1 cardiotrophin like cytokine factor 1 involved_in ISO (MGI:3777853|PMID:12023368) BHF-UCL PMID:12023368 MGI:3777853 NCBI chrNW_004624767:19,142,927...19,152,572
Ensembl chrNW_004624767:19,142,852...19,153,155 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:14988498) MGI PMID:14988498 NCBI chrNW_004624733:39,412,800...39,420,079 JBrowse link
G Stat6 signal transducer and activator of transcription 6 acts_upstream_of_or_within ISO (PMID:10490661) MGI PMID:10490661 NCBI chrNW_004624802:10,809,234...10,847,762
Ensembl chrNW_004624802:10,809,252...10,846,693 		JBrowse link
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family AAA domain containing 5 acts_upstream_of_or_within ISO (PMID:25404367) MGI PMID:25404367 NCBI chrNW_004624875:97,048...154,420
Ensembl chrNW_004624875:97,670...151,080 		JBrowse link
G Cd28 CD28 molecule acts_upstream_of_or_within ISO (PMID:7688139) MGI PMID:7688139 NCBI chrNW_004624765:12,650,092...12,667,168 JBrowse link
G Cd40 CD40 molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12882831) TreeGrafter
MGI		 PMID:12882831 GO_REF:0000118 NCBI chrNW_004624790:8,475,640...8,485,927
Ensembl chrNW_004624790:8,476,158...8,485,856 		JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:12882831) MGI PMID:12882831 NCBI chrNW_004624802:163,261...166,534
Ensembl chrNW_004624802:163,261...166,534 		JBrowse link
G Il2 interleukin 2 acts_upstream_of_or_within ISO (PMID:1830926) MGI PMID:1830926 NCBI chrNW_004624777:2,885,537...2,890,453
Ensembl chrNW_004624777:2,885,535...2,890,453 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:12882831), (PMID:14988498) MGI PMID:12882831 PMID:14988498 NCBI chrNW_004624733:39,412,800...39,420,079 JBrowse link
G Mlh1 mutL homolog 1 involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chrNW_004624788:15,110,436...15,160,462
Ensembl chrNW_004624788:15,110,658...15,160,535 		JBrowse link
G Msh2 mutS homolog 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624738:28,780,596...28,861,523
Ensembl chrNW_004624738:28,780,614...28,861,704 		JBrowse link
G Pagr1 PAXIP1 associated glutamate rich protein 1 involved_in ISO (MGI:5752090|PMID:26744420) UniProt PMID:26744420 MGI:5752090 NCBI chrNW_004624782:13,387,155...13,390,153
Ensembl chrNW_004624782:13,387,376...13,389,740 		JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (MGI:5752090|PMID:26744420) UniProt PMID:26744420 MGI:5752090 NCBI chrNW_004624800:2,653,381...2,709,261
Ensembl chrNW_004624800:2,653,732...2,707,161 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in ISO (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chrNW_004624740:31,315,121...31,345,137 JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of_or_within ISO (PMID:9015183) MGI PMID:9015183 NCBI chrNW_004624798:1,700,732...1,814,603
Ensembl chrNW_004624798:1,699,541...1,814,656 		JBrowse link
G Tbx21 T-box transcription factor 21 acts_upstream_of_or_within ISO (PMID:12882831) MGI PMID:12882831 NCBI chrNW_004624795:4,442,188...4,453,544
Ensembl chrNW_004624795:4,442,188...4,453,143 		JBrowse link
positive regulation of type I hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase ISO RGD PMID:22228807 RGD:11040701 NCBI chrNW_004624902:1,173,101...1,216,662
Ensembl chrNW_004624902:1,182,682...1,216,171 		JBrowse link
G Fcer1a Fc fragment of IgE receptor Ia acts_upstream_of_or_within ISO (PMID:8252632) MGI PMID:8252632 NCBI chrNW_004624794:2,003,031...2,008,930
Ensembl chrNW_004624794:2,002,928...2,008,940 		JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig acts_upstream_of_or_within ISO (PMID:14764707) MGI PMID:14764707 NCBI chrNW_004624794:168,564...172,433
Ensembl chrNW_004624794:168,564...172,034 		JBrowse link
positive regulation of type IIa hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 acts_upstream_of_or_within ISO (PMID:11901193) MGI PMID:11901193 NCBI chrNW_004624828:3,773,816...3,798,077
Ensembl chrNW_004624828:3,770,221...3,797,946 		JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig acts_upstream_of_or_within ISO (PMID:11901193), (PMID:11911824)
(PMID:8976192)		 MGI PMID:8976192 PMID:11901193 PMID:11911824 NCBI chrNW_004624794:168,564...172,433
Ensembl chrNW_004624794:168,564...172,034 		JBrowse link
positive regulation of type III hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase ISO RGD PMID:22228807 RGD:11040701 NCBI chrNW_004624902:1,173,101...1,216,662
Ensembl chrNW_004624902:1,182,682...1,216,171 		JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig acts_upstream_of_or_within ISO (PMID:8976192) MGI PMID:8976192 NCBI chrNW_004624794:168,564...172,433
Ensembl chrNW_004624794:168,564...172,034 		JBrowse link
regulation of antibody-dependent cellular cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcgr2a Fc fragment of IgG receptor IIa ISO RGD PMID:16482158 RGD:2293335 NCBI chrNW_004624826:23,930...34,735 JBrowse link
regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd55 CD55 molecule (Cromer blood group) acts_upstream_of_or_within ISO (PMID:9892684) MGI PMID:9892684 NCBI chrNW_004624807:4,252,676...4,274,828 JBrowse link
regulation of humoral immune response mediated by circulating immunoglobulin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of_or_within ISO (PMID:9015183) MGI PMID:9015183 NCBI chrNW_004624798:1,700,732...1,814,603
Ensembl chrNW_004624798:1,699,541...1,814,656 		JBrowse link
regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aplf aprataxin and PNKP like factor acts_upstream_of_or_within ISO (PMID:21211721) MGI PMID:21211721 NCBI chrNW_004624762:4,727,834...4,847,779
Ensembl chrNW_004624762:4,724,813...4,847,416 		JBrowse link
G Supt6h SPT6 homolog, histone chaperone and transcription elongation factor involved_in ISO (MGI:5004983|PMID:21518874) UniProt PMID:21518874 MGI:5004983 NCBI chrNW_004624786:1,226,131...1,271,872
Ensembl chrNW_004624786:1,238,082...1,271,875 		JBrowse link
regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO (PMID:16275384) MGI PMID:16275384 NCBI chrNW_004624893:995,145...1,008,492
Ensembl chrNW_004624893:995,182...1,008,679 		JBrowse link
G Il27ra interleukin 27 receptor subunit alpha acts_upstream_of_or_within ISO (PMID:11057672) MGI PMID:11057672 NCBI chrNW_004624901:1,274,753...1,288,783
Ensembl chrNW_004624901:1,274,840...1,287,861 		JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within ISO (PMID:17137798) MGI PMID:17137798 NCBI chrNW_004624774:1,245,587...1,353,253
Ensembl chrNW_004624774:1,303,773...1,353,253 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in ISO (MGI:5649169|PMID:25310967) UniProt PMID:25310967 MGI:5649169 NCBI chrNW_004624747:26,252,788...26,275,273
Ensembl chrNW_004624747:26,252,492...26,275,173 		JBrowse link
somatic recombination of immunoglobulin genes involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 acts_upstream_of_or_within ISO (PMID:12743174) MGI PMID:12743174 NCBI chrNW_004624788:15,110,436...15,160,462
Ensembl chrNW_004624788:15,110,658...15,160,535 		JBrowse link
G Msh2 mutS homolog 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12743174) TreeGrafter
MGI
Ensembl		 PMID:12743174 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624738:28,780,596...28,861,523
Ensembl chrNW_004624738:28,780,614...28,861,704 		JBrowse link
type I hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1a Fc fragment of IgE receptor Ia involved_in ISO (PMID:8551243) UniProt PMID:8551243 NCBI chrNW_004624794:2,003,031...2,008,930
Ensembl chrNW_004624794:2,002,928...2,008,940 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15093
    immune system process 2103
      immune effector process 553
        leukocyte mediated immunity 342
          lymphocyte mediated immunity 245
            B cell mediated immunity 123
              immunoglobulin mediated immune response 121
                humoral immune response mediated by circulating immunoglobulin + 38
                immune complex formation 1
                immunoglobulin production involved in immunoglobulin-mediated immune response + 59
                immunoglobulin-mediated neutralization 0
                negative regulation of immunoglobulin mediated immune response + 12
                positive regulation of immunoglobulin mediated immune response + 44
                regulation of immunoglobulin mediated immune response + 62
                type I hypersensitivity + 4
                type II hypersensitivity + 4
                type III hypersensitivity + 2
paths to the root