Foxj1 (forkhead box J1) - Rat Genome Database

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Gene: Foxj1 (forkhead box J1) Heterocephalus glaber
Analyze
Symbol: Foxj1
Name: forkhead box J1
RGD ID: 18902145
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN activation of GTPase activity (ortholog); cell maturation (ortholog); cellular response to insulin-like growth factor stimulus (ortholog); ASSOCIATED WITH congenital heart disease (ortholog); genetic disease (ortholog); Kartagener syndrome (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Forkhead box protein J1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248016,025,793 - 6,030,486 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248016,025,756 - 6,030,487 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
actin cytoskeleton organization  (IEA)
activation of GTPase activity  (ISO)
axoneme assembly  (IEA)
brain development  (IEA)
cell maturation  (IEA,ISO)
cell projection organization  (IEA)
cellular response to insulin-like growth factor stimulus  (ISO)
central tolerance induction  (IEA)
ciliary basal body organization  (IEA)
cilium assembly  (IEA)
determination of left/right symmetry  (IEA,ISO)
developmental process  (IEA)
epithelium development  (IEA)
establishment of apical/basal cell polarity  (IEA,ISO)
glomerular parietal epithelial cell development  (IEA)
heart development  (IEA,ISO)
humoral immune response  (IEA)
left/right pattern formation  (IEA,ISO)
leukocyte migration  (IEA)
lung epithelium development  (IEA)
metanephric part of ureteric bud development  (IEA)
motile cilium assembly  (IEA,ISO)
negative regulation of B cell activation  (IEA)
negative regulation of germinal center formation  (IEA)
negative regulation of humoral immune response mediated by circulating immunoglobulin  (IEA)
negative regulation of interleukin-6 production  (IEA)
negative regulation of NF-kappaB transcription factor activity  (ISO)
negative regulation of T cell differentiation in thymus  (IEA)
negative regulation of T cell proliferation  (IEA)
negative regulation of transcription by RNA polymerase II  (IEA)
positive regulation of central B cell tolerance induction  (IEA)
positive regulation of DNA-templated transcription  (IEA)
positive regulation of lung ciliated cell differentiation  (IEA)
positive regulation of transcription by RNA polymerase II  (IEA,ISO)
protein localization  (IEA)
regulation of DNA-templated transcription  (IEA)
regulation of epithelial cell differentiation  (IEA,ISO)
regulation of transcription by RNA polymerase II  (IEA)
response to 2,3,7,8-tetrachlorodibenzodioxine  (ISO)
response to estradiol  (ISO)
spermatogenesis  (ISO)

Cellular Component
nucleus  (IEA)

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Foxj1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248016,025,793 - 6,030,486 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248016,025,756 - 6,030,487 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
FOXJ1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381776,136,333 - 76,141,245 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1776,136,333 - 76,141,245 (-)EnsemblGRCh38hg38GRCh38
GRCh371774,132,414 - 74,137,326 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361771,644,009 - 71,648,161 (-)NCBINCBI36Build 36hg18NCBI36
Build 341771,644,011 - 71,648,161NCBI
Celera1770,726,321 - 70,731,288 (-)NCBICelera
Cytogenetic Map17q25.1NCBI
HuRef1769,561,375 - 69,566,342 (-)NCBIHuRef
CHM1_11774,197,328 - 74,202,294 (-)NCBICHM1_1
T2T-CHM13v2.01777,032,876 - 77,037,788 (-)NCBIT2T-CHM13v2.0
Foxj1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911116,221,530 - 116,226,331 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11116,221,530 - 116,226,225 (-)EnsemblGRCm39 Ensembl
GRCm3811116,330,704 - 116,335,499 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11116,330,704 - 116,335,399 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711116,192,018 - 116,196,668 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611116,146,794 - 116,151,437 (-)NCBIMGSCv36mm8
Celera11128,095,035 - 128,099,811 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1181.16NCBI
Foxj1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810102,065,163 - 102,069,945 (-)NCBIGRCr8
mRatBN7.210101,566,299 - 101,570,370 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10101,566,304 - 101,570,237 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10106,622,776 - 106,626,846 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010106,085,863 - 106,089,933 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010101,487,207 - 101,491,279 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010105,282,090 - 105,289,396 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.010104,946,564 - 104,980,556 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera10100,138,561 - 100,142,396 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
Foxj1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555066,127,551 - 6,132,302 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555066,127,551 - 6,132,302 (+)NCBIChiLan1.0ChiLan1.0
FOXJ1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21992,179,721 - 92,184,680 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11797,004,916 - 97,009,875 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01770,084,920 - 70,089,865 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11775,637,615 - 75,642,571 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1775,638,634 - 75,641,666 (-)Ensemblpanpan1.1panPan2
FOXJ1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.194,512,898 - 4,517,764 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl94,513,628 - 4,517,756 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha95,193,269 - 5,198,295 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.095,183,268 - 5,188,294 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl95,183,630 - 5,188,286 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.195,223,122 - 5,228,148 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.095,332,544 - 5,337,565 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.095,393,019 - 5,398,045 (+)NCBIUU_Cfam_GSD_1.0
Foxj1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056025,122,576 - 5,127,166 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365941,284,781 - 1,289,361 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365941,284,799 - 1,288,898 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FOXJ1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl125,307,374 - 5,312,106 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1125,307,370 - 5,312,117 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2125,211,688 - 5,216,414 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FOXJ1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11645,536,973 - 45,544,331 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1645,539,510 - 45,544,299 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607716,286,720 - 16,291,692 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000027143   ⟹   ENSHGLP00000026904
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248016,025,793 - 6,030,486 (-)Ensembl
RefSeq Acc Id: XM_004860741   ⟹   XP_004860798
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248016,025,756 - 6,030,487 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004860798 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHA99415 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000026904
GenBank Protein JAN96175 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004860798   ⟸   XM_004860741
- UniProtKB: G5AQV5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000026904   ⟸   ENSHGLT00000027143


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000019133 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000027143 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
InterPro FH_FOXJ1 UniProtKB/TrEMBL
  Fork_head_dom UniProtKB/TrEMBL
  FOXJ1 UniProtKB/TrEMBL
  TF_fork_head_CS_1 UniProtKB/TrEMBL
  TF_fork_head_CS_2 UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
KEGG Report hgl:101708847 UniProtKB/TrEMBL
NCBI Gene Foxj1 ENTREZGENE
PANTHER FORKHEAD BOX PROTEIN J1 UniProtKB/TrEMBL
  FORKHEAD BOX PROTEIN J1 UniProtKB/TrEMBL
Pfam Forkhead UniProtKB/TrEMBL
PRINTS FORKHEAD UniProtKB/TrEMBL
PROSITE FORK_HEAD_1 UniProtKB/TrEMBL
  FORK_HEAD_2 UniProtKB/TrEMBL
  FORK_HEAD_3 UniProtKB/TrEMBL
SMART SM00339 UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
UniProt G5AQV5 ENTREZGENE, UniProtKB/TrEMBL