FOXJ1 (forkhead box J1) - Rat Genome Database

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Gene: FOXJ1 (forkhead box J1) Canis lupus familiaris
Analyze
Symbol: FOXJ1
Name: forkhead box J1
RGD ID: 12333050
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN activation of GTPase activity (ortholog); cellular response to insulin-like growth factor stimulus (ortholog); motile cilium assembly (ortholog); ASSOCIATED WITH congenital heart disease (ortholog); genetic disease (ortholog); Kartagener syndrome (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: forkhead box protein J1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.194,512,898 - 4,517,764 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl94,513,628 - 4,517,756 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha95,193,269 - 5,198,295 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.095,183,268 - 5,188,294 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl95,183,630 - 5,188,286 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.195,223,122 - 5,228,148 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.095,332,544 - 5,337,565 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.095,393,019 - 5,398,045 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
actin cytoskeleton organization  (IEA)
activation of GTPase activity  (ISO)
axoneme assembly  (IEA)
brain development  (IEA)
cell maturation  (IEA)
cell projection organization  (IEA)
cellular response to insulin-like growth factor stimulus  (ISO)
central tolerance induction  (IEA)
ciliary basal body organization  (IEA)
cilium assembly  (IEA)
determination of left/right symmetry  (IEA)
epithelium development  (IEA)
establishment of apical/basal cell polarity  (IEA)
glomerular parietal epithelial cell development  (IEA)
heart development  (IEA)
humoral immune response  (IEA)
left/right pattern formation  (IEA)
leukocyte migration  (IEA)
lung epithelium development  (IEA)
metanephric part of ureteric bud development  (IEA)
motile cilium assembly  (IEA,ISO)
negative regulation of B cell activation  (IEA)
negative regulation of germinal center formation  (IEA)
negative regulation of humoral immune response mediated by circulating immunoglobulin  (IEA)
negative regulation of interleukin-6 production  (IEA)
negative regulation of NF-kappaB transcription factor activity  (ISO)
negative regulation of non-canonical NF-kappaB signal transduction  (IEA)
negative regulation of T cell differentiation in thymus  (IEA)
negative regulation of T cell proliferation  (IEA)
negative regulation of transcription by RNA polymerase II  (IEA)
positive regulation of central B cell tolerance induction  (IEA)
positive regulation of DNA-templated transcription  (IEA)
positive regulation of lung ciliated cell differentiation  (IEA)
positive regulation of transcription by RNA polymerase II  (IEA)
protein localization  (IEA)
regulation of DNA-templated transcription  (IEA)
regulation of epithelial cell differentiation  (IEA)
regulation of transcription by RNA polymerase II  (IBA)
response to 2,3,7,8-tetrachlorodibenzodioxine  (ISO)
response to estradiol  (ISO)
spermatogenesis  (ISO)

Cellular Component
nucleus  (IBA,IEA)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
FOXJ1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.194,512,898 - 4,517,764 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl94,513,628 - 4,517,756 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha95,193,269 - 5,198,295 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.095,183,268 - 5,188,294 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl95,183,630 - 5,188,286 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.195,223,122 - 5,228,148 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.095,332,544 - 5,337,565 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.095,393,019 - 5,398,045 (+)NCBIUU_Cfam_GSD_1.0
FOXJ1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381776,136,333 - 76,141,245 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1776,136,333 - 76,141,245 (-)EnsemblGRCh38hg38GRCh38
GRCh371774,132,414 - 74,137,326 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361771,644,009 - 71,648,161 (-)NCBINCBI36Build 36hg18NCBI36
Build 341771,644,011 - 71,648,161NCBI
Celera1770,726,321 - 70,731,288 (-)NCBICelera
Cytogenetic Map17q25.1NCBI
HuRef1769,561,375 - 69,566,342 (-)NCBIHuRef
CHM1_11774,197,328 - 74,202,294 (-)NCBICHM1_1
T2T-CHM13v2.01777,032,876 - 77,037,788 (-)NCBIT2T-CHM13v2.0
Foxj1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911116,221,530 - 116,226,331 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11116,221,530 - 116,226,225 (-)EnsemblGRCm39 Ensembl
GRCm3811116,330,704 - 116,335,499 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11116,330,704 - 116,335,399 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711116,192,018 - 116,196,668 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611116,146,794 - 116,151,437 (-)NCBIMGSCv36mm8
Celera11128,095,035 - 128,099,811 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1181.16NCBI
Foxj1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810102,065,163 - 102,069,945 (-)NCBIGRCr8
mRatBN7.210101,566,299 - 101,570,370 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10101,566,304 - 101,570,237 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10106,622,776 - 106,626,846 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010106,085,863 - 106,089,933 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010101,487,207 - 101,491,279 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010105,282,090 - 105,289,396 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.010104,946,564 - 104,980,556 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera10100,138,561 - 100,142,396 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
Foxj1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555066,127,551 - 6,132,302 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555066,127,551 - 6,132,302 (+)NCBIChiLan1.0ChiLan1.0
FOXJ1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21992,179,721 - 92,184,680 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11797,004,916 - 97,009,875 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01770,084,920 - 70,089,865 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11775,637,615 - 75,642,571 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1775,638,634 - 75,641,666 (-)Ensemblpanpan1.1panPan2
Foxj1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056025,122,576 - 5,127,166 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365941,284,781 - 1,289,361 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365941,284,799 - 1,288,898 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FOXJ1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl125,307,374 - 5,312,106 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1125,307,370 - 5,312,117 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2125,211,688 - 5,216,414 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FOXJ1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11645,536,973 - 45,544,331 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1645,539,510 - 45,544,299 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607716,286,720 - 16,291,692 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Foxj1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248016,025,793 - 6,030,486 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248016,025,756 - 6,030,487 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in FOXJ1
56 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 4 23 22 16 6 5 6 6 28 17 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000008129   ⟹   ENSCAFP00000007529
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl94,513,628 - 4,517,756 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845033966   ⟹   ENSCAFP00845026580
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl95,183,630 - 5,188,286 (+)Ensembl
RefSeq Acc Id: XM_005624062   ⟹   XP_005624119
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.194,512,898 - 4,517,764 (+)NCBI
Dog10K_Boxer_Tasha95,193,269 - 5,198,295 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038487577   ⟹   XP_038343505
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.195,223,122 - 5,228,148 (+)NCBI
RefSeq Acc Id: XM_038487578   ⟹   XP_038343506
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.195,223,122 - 5,228,148 (+)NCBI
RefSeq Acc Id: XM_038546082   ⟹   XP_038402010
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.095,393,019 - 5,398,045 (+)NCBI
RefSeq Acc Id: XM_038546083   ⟹   XP_038402011
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.095,393,019 - 5,398,045 (+)NCBI
RefSeq Acc Id: XM_038610107   ⟹   XP_038466035
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.095,332,544 - 5,337,565 (+)NCBI
RefSeq Acc Id: XM_038610108   ⟹   XP_038466036
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.095,332,544 - 5,337,565 (+)NCBI
RefSeq Acc Id: XM_038675174   ⟹   XP_038531102
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.095,183,268 - 5,188,294 (+)NCBI
RefSeq Acc Id: XM_038675175   ⟹   XP_038531103
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.095,183,268 - 5,188,294 (+)NCBI
RefSeq Acc Id: XM_533124   ⟹   XP_533124
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.194,512,898 - 4,517,764 (+)NCBI
Dog10K_Boxer_Tasha95,193,269 - 5,198,295 (+)NCBI
Sequence:
RefSeq Acc Id: XP_005624119   ⟸   XM_005624062
- UniProtKB: A0A8C0JXZ1 (UniProtKB/TrEMBL),   A0A8C0PRJ7 (UniProtKB/TrEMBL),   A0A8I3P9M6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_533124   ⟸   XM_533124
- UniProtKB: A0A8C0JXZ1 (UniProtKB/TrEMBL),   A0A8C0PRJ7 (UniProtKB/TrEMBL),   A0A8I3P9M6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000007529   ⟸   ENSCAFT00000008129
RefSeq Acc Id: XP_038343505   ⟸   XM_038487577
RefSeq Acc Id: XP_038343506   ⟸   XM_038487578
RefSeq Acc Id: XP_038466035   ⟸   XM_038610107
RefSeq Acc Id: XP_038466036   ⟸   XM_038610108
RefSeq Acc Id: XP_038531102   ⟸   XM_038675174
- UniProtKB: A0A8C0JXZ1 (UniProtKB/TrEMBL),   A0A8C0PRJ7 (UniProtKB/TrEMBL),   A0A8I3P9M6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038531103   ⟸   XM_038675175
- UniProtKB: A0A8C0JXZ1 (UniProtKB/TrEMBL),   A0A8C0PRJ7 (UniProtKB/TrEMBL),   A0A8I3P9M6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038402010   ⟸   XM_038546082
- UniProtKB: A0A8C0JXZ1 (UniProtKB/TrEMBL),   A0A8C0PRJ7 (UniProtKB/TrEMBL),   A0A8I3P9M6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038402011   ⟸   XM_038546083
- UniProtKB: A0A8C0JXZ1 (UniProtKB/TrEMBL),   A0A8C0PRJ7 (UniProtKB/TrEMBL),   A0A8I3P9M6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845026580   ⟸   ENSCAFT00845033966
Protein Domains
Fork-head

Promoters
RGD ID:13684413
Promoter ID:EPDNEW_C2480
Type:single initiation site
Name:FOXJ1_1
Description:forkhead box J1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.194,513,720 - 4,513,780EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000005050 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030001188 UniProtKB/TrEMBL
  ENSCAFG00040000832 UniProtKB/TrEMBL
  ENSCAFG00845019264 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000008129.5 UniProtKB/TrEMBL
  ENSCAFT00030002071.1 UniProtKB/TrEMBL
  ENSCAFT00040001498.1 UniProtKB/TrEMBL
  ENSCAFT00845033966 ENTREZGENE
  ENSCAFT00845033966.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
InterPro FH_FOXJ1 UniProtKB/TrEMBL
  Fork_head_dom UniProtKB/TrEMBL
  FOXJ1 UniProtKB/TrEMBL
  TF_fork_head_CS_1 UniProtKB/TrEMBL
  TF_fork_head_CS_2 UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
KEGG Report cfa:475917 UniProtKB/TrEMBL
NCBI Gene FOXJ1 ENTREZGENE
PANTHER FORKHEAD BOX PROTEIN J1 UniProtKB/TrEMBL
  FORKHEAD BOX PROTEIN J1 UniProtKB/TrEMBL
Pfam Forkhead UniProtKB/TrEMBL
PRINTS FORKHEAD UniProtKB/TrEMBL
PROSITE FORK_HEAD_1 UniProtKB/TrEMBL
  FORK_HEAD_2 UniProtKB/TrEMBL
  FORK_HEAD_3 UniProtKB/TrEMBL
SMART SM00339 UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
UniProt A0A8C0JXZ1 ENTREZGENE
  A0A8C0PRJ7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3P9M6 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:40954 ENTREZGENE