ONTOLOGY REPORT - ANNOTATIONS
Term: type II hypersensitivity
Accession: GO:0002445
browse the term
Definition: An inflammatory response resulting in cell death or dysfunction mediated by activation of the classical complement pathway or induction of effector cell phagocytosis, cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell, or mediated by the direct binding of antibody to cellular receptors.
Synonyms: xref: Wikipedia:Type_II_hypersensitivity
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Fcgr1a
Fc fragment of IgG receptor Ia
ISO
MGI:2664927|MGI:2679238 (MGI:2664488|PMID:11911824), (MGI:2679189|PMID:11911823)
RGD
PMID:11911823 PMID:11911824
MGI:2664488 MGI:2679189
NCBI chr 2:198,430,536...198,439,453
Ensembl chr 2:198,430,530...198,458,041
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Fcgr2a
Fc fragment of IgG receptor IIa
ISO
MGI:1861924 (MGI:2683749|PMID:9743367), (MGI:82508|PMID:8769481)
RGD
PMID:8769481 PMID:9743367
MGI:2683749 MGI:82508
NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036 Ensembl chr13:91,168,973...91,198,036
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Ighg1
immunoglobulin heavy constant gamma 1
ISO
(MGI:2683749|PMID:9743367)
RGD
PMID:9743367
MGI:2683749
NCBI chr 6:139,140,572...139,784,388
Ensembl chr 6:139,140,679...139,142,218
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RT1-S3
RT1 class Ib, locus S3
involved_in
ISO
(PMID:30134159)
RGD
PMID:30134159
NCBI chr20:3,176,124...3,180,825
Ensembl chr20:3,176,107...3,179,818
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C3
complement C3
involved_in
IEA ISO
GO_REF:0000107 MGI:1861799 (MGI:2177393|PMID:11901193)
Ensembl RGD
PMID:11901193
GO_REF:0000107 MGI:2177393
NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
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Fcer1g
Fc fragment of IgE receptor Ig
ISO
MGI:1857165|MGI:2384004 (MGI:2177393|PMID:11901193), (MGI:2383973|PMID:8976192), (MGI:2664488|PMID:11911824)
RGD
PMID:8976192 PMID:11901193 PMID:11911824
MGI:2177393 MGI:2383973 MGI:2664488
NCBI chr13:89,601,894...89,606,326
Ensembl chr13:89,601,896...89,606,326
G
Fcgr1a
Fc fragment of IgG receptor Ia
ISO
MGI:2664927 (MGI:2664488|PMID:11911824)
RGD
PMID:11911824
MGI:2664488
NCBI chr 2:198,430,536...198,439,453
Ensembl chr 2:198,430,530...198,458,041
G
Fcgr2a
Fc fragment of IgG receptor IIa
ISO
MGI:1861924 (MGI:2664488|PMID:11911824), (MGI:2683747|PMID:9834201)
RGD
PMID:9834201 PMID:11911824
MGI:2664488 MGI:2683747
NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036 Ensembl chr13:91,168,973...91,198,036
G
Ighg1
immunoglobulin heavy constant gamma 1
ISO
(MGI:2177393|PMID:11901193), (MGI:2683747|PMID:9834201)
RGD
PMID:9834201 PMID:11901193
MGI:2177393 MGI:2683747
NCBI chr 6:139,140,572...139,784,388
Ensembl chr 6:139,140,679...139,142,218
G
Fcgr2a
Fc fragment of IgG receptor IIa
IMP
RGD
PMID:16482158
RGD:2293335
NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036 Ensembl chr13:91,168,973...91,198,036
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