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ONTOLOGY REPORT - ANNOTATIONS


Term:type III hypersensitivity
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Accession:GO:0001802 term browser browse the term
Definition:An inflammatory response resulting from recognition of immune complexes via complement or Fc receptors on effector cells leading to activation of neutrophils and other leukocytes and damage to bystander tissue.
Comment:Note that the Arthus reaction is an example of type III hypersensitivity.
Synonyms:xref: Wikipedia:Type_III_hypersensitivity


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positive regulation of type III hypersensitivity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase IMP RGD PMID:22228807 RGD:11040701 NCBI chr  X:105,360,922...105,390,580
Ensembl chr  X:105,360,922...105,390,580
JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig ISO MGI:1857165 (MGI:2383973|PMID:8976192) RGD PMID:8976192 MGI:2383973 NCBI chr13:89,601,894...89,606,326
Ensembl chr13:89,601,896...89,606,326
JBrowse link
G Fcgr1a Fc fragment of IgG receptor Ia ISO MGI:2679238 (MGI:2679189|PMID:11911823) RGD PMID:11911823 MGI:2679189 NCBI chr 2:198,430,536...198,439,453
Ensembl chr 2:198,430,530...198,458,041
JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa ISO MGI:1861924 (MGI:82508|PMID:8769481) RGD PMID:8769481 MGI:82508 NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036
Ensembl chr13:91,168,973...91,198,036
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20078
    immune system process 2843
      immune effector process 902
        leukocyte mediated immunity 513
          myeloid leukocyte mediated immunity 125
            type III hypersensitivity 4
              negative regulation of type III hypersensitivity 0
              positive regulation of type III hypersensitivity 4
              regulation of type III hypersensitivity + 4
Path 2
Term Annotations click to browse term
  biological_process 20078
    response to stimulus 10589
      response to stress 4054
        defense response 1677
          inflammatory response 732
            inflammatory response to antigenic stimulus 85
              acute inflammatory response to antigenic stimulus 36
                hypersensitivity 17
                  type III hypersensitivity 4
                    negative regulation of type III hypersensitivity 0
                    positive regulation of type III hypersensitivity 4
                    regulation of type III hypersensitivity + 4
paths to the root