Nbn (nibrin) - Rat Genome Database

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Gene: Nbn (nibrin) Heterocephalus glaber
Analyze
Symbol: Nbn
Name: nibrin
RGD ID: 18936520
Description: ENCODES a protein that exhibits chromatin-protein adaptor activity (ortholog); damaged DNA binding (ortholog); DNA-binding transcription factor binding (ortholog); INVOLVED IN blastocyst growth (ortholog); blocking of symbiont entry into host cell (ortholog); DNA damage checkpoint signaling (ortholog); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; homologous recombination pathway of double-strand break repair; ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); Alzheimer's disease (ortholog); aplastic anemia (ortholog); FOUND IN BRCA1-C complex (ortholog); chromosome, telomeric region (ortholog); Golgi apparatus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247442,013,922 - 2,061,708 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247442,013,936 - 2,061,726 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Nbn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247442,013,922 - 2,061,708 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247442,013,936 - 2,061,726 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
NBN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38889,933,331 - 89,984,667 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl889,924,515 - 90,003,228 (-)EnsemblGRCh38hg38GRCh38
GRCh37890,945,559 - 90,996,895 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36891,014,740 - 91,066,075 (-)NCBINCBI36Build 36hg18NCBI36
Build 34891,014,888 - 91,066,072NCBI
Celera887,140,375 - 87,191,710 (-)NCBICelera
Cytogenetic Map8q21.3NCBI
HuRef886,155,741 - 86,207,078 (-)NCBIHuRef
CHM1_1890,986,489 - 91,037,825 (-)NCBICHM1_1
T2T-CHM13v2.0891,056,512 - 91,107,848 (-)NCBIT2T-CHM13v2.0
Nbn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39415,955,388 - 15,992,589 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl415,957,925 - 15,992,589 (+)EnsemblGRCm39 Ensembl
GRCm38415,957,587 - 15,992,589 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl415,957,925 - 15,992,589 (+)EnsemblGRCm38mm10GRCm38
MGSCv37415,885,114 - 15,919,736 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36415,885,115 - 15,919,736 (+)NCBIMGSCv36mm8
Celera415,761,229 - 15,795,887 (+)NCBICelera
Cytogenetic Map4A2NCBI
cM Map46.66NCBI
Nbn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8534,256,678 - 34,291,163 (+)NCBIGRCr8
mRatBN7.2529,459,574 - 29,494,152 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl529,459,457 - 29,494,150 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx531,615,796 - 31,650,590 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0533,208,466 - 33,243,256 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0533,168,642 - 33,203,436 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0529,622,347 - 29,656,877 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl529,622,281 - 29,656,864 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0534,300,932 - 34,335,393 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4530,541,610 - 30,576,168 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1530,541,609 - 30,576,168 (+)NCBI
Celera528,665,088 - 28,699,404 (+)NCBICelera
Cytogenetic Map5q13NCBI
Nbn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554176,839,312 - 6,880,133 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554176,840,916 - 6,880,479 (-)NCBIChiLan1.0ChiLan1.0
NBN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27107,329,160 - 107,380,523 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1882,868,830 - 82,938,522 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0886,622,797 - 86,674,202 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1888,575,198 - 88,626,200 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl888,575,198 - 88,626,307 (-)Ensemblpanpan1.1panPan2
NBN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12935,416,093 - 35,477,569 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2935,416,093 - 35,477,563 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2935,567,773 - 35,628,935 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02935,612,774 - 35,674,851 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2935,612,774 - 35,692,878 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12935,604,159 - 35,665,432 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02935,624,597 - 35,685,889 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02936,059,084 - 36,120,657 (-)NCBIUU_Cfam_GSD_1.0
Nbn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530343,980,776 - 44,018,864 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365443,775,220 - 3,808,837 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365443,773,828 - 3,812,673 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NBN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl446,787,691 - 46,874,603 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1446,787,664 - 46,854,331 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2451,264,106 - 51,288,533 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NBN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1885,017,807 - 85,069,219 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl885,015,752 - 85,069,028 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603955,810,092 - 55,861,864 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000013417   ⟹   ENSHGLP00000013278
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247442,013,922 - 2,061,708 (+)Ensembl
RefSeq Acc Id: XM_013071257   ⟹   XP_012926711
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247442,013,937 - 2,061,726 (+)NCBI
RefSeq Acc Id: XM_021255962   ⟹   XP_021111621
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247442,013,936 - 2,061,726 (+)NCBI
RefSeq Acc Id: XM_021255963   ⟹   XP_021111622
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247442,013,938 - 2,061,726 (+)NCBI
RefSeq Acc Id: XM_021255964   ⟹   XP_021111623
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247442,014,725 - 2,061,726 (+)NCBI
Protein Sequences
Protein RefSeqs XP_012926711 (Get FASTA)   NCBI Sequence Viewer  
  XP_021111621 (Get FASTA)   NCBI Sequence Viewer  
  XP_021111622 (Get FASTA)   NCBI Sequence Viewer  
  XP_021111623 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000013278
RefSeq Acc Id: XP_021111621   ⟸   XM_021255962
- Peptide Label: isoform X2
RefSeq Acc Id: XP_012926711   ⟸   XM_013071257
- Peptide Label: isoform X1
RefSeq Acc Id: XP_021111622   ⟸   XM_021255963
- Peptide Label: isoform X3
RefSeq Acc Id: XP_021111623   ⟸   XM_021255964
- Peptide Label: isoform X4
Ensembl Acc Id: ENSHGLP00000013278   ⟸   ENSHGLT00000013417


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000009487 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000013417 ENTREZGENE
NCBI Gene Nbn ENTREZGENE