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ONTOLOGY REPORT - ANNOTATIONS

Term:chemokine activity
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Accession:GO:0008009 term browser browse the term
Definition:The function of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.


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chemokine activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl1 C-C motif chemokine ligand 1 enables ISO
IEA
IBA		 GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000119 NCBI chr11:82,067,492...82,070,638
Ensembl chr11:82,067,483...82,196,516 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 enables ISO
IEA
IBA		 RGD
GO_Central
Ensembl		 PMID:9458816 GO_REF:0000033 GO_REF:0000096 GO_REF:0000107 GO_REF:0000119 RGD:69985 NCBI chr11:81,948,658...81,953,781
Ensembl chr11:81,948,649...81,953,781 		JBrowse link
G Ccl12 C-C motif chemokine ligand 12 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr11:81,992,671...81,994,225
Ensembl chr11:81,992,671...81,994,226 		JBrowse link
G Ccl17 C-C motif chemokine ligand 17 enables TAS (PMID:9835618) MGI PMID:9835618 NCBI chr 8:95,535,996...95,538,666
Ensembl chr 8:95,537,081...95,538,664 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 enables IDA
ISO
IBA		 (PMID:12200351) BHF-UCL
GO_Central		 PMID:12200351 GO_REF:0000033 GO_REF:0000119 NCBI chr 4:42,754,525...42,756,558
Ensembl chr 4:42,754,525...42,756,577 		JBrowse link
G Ccl19-ps1 C-C motif chemokine ligand 19, pseudogene 1 enables ISO GO_Central GO_REF:0000119 NCBI chr 4:41,921,279...41,923,225
Ensembl chr 4:41,920,558...41,923,235 		JBrowse link
G Ccl19-ps3 C-C motif chemokine ligand 19, pseudogene 3 enables ISO GO_Central GO_REF:0000119 NCBI chr 4:42,132,521...42,134,376
Ensembl chr 4:42,132,559...42,134,171 		JBrowse link
G Ccl19-ps4 C-C motif chemokine ligand 19, pseudogene 4 enables ISO GO_Central GO_REF:0000119 NCBI chr 4:42,629,753...42,631,714
Ensembl chr 4:42,629,897...42,631,507 		JBrowse link
G Ccl19-ps5 C-C motif chemokine ligand 19, pseudogene 5 enables ISO GO_Central GO_REF:0000119 NCBI chr 4:41,791,784...41,793,745
Ensembl chr 4:41,791,989...41,793,601
Ensembl chr 4:41,791,989...41,793,601 		JBrowse link
G Ccl19-ps6 C-C motif chemokine ligand 19, pseudogene 6 enables ISO GO_Central GO_REF:0000119 NCBI chr 4:42,070,757...42,072,794
Ensembl chr 4:42,070,962...42,072,563
Ensembl chr 4:42,070,962...42,072,563 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 enables ISO
IEA
IBA		 RGD
GO_Central
Ensembl		 PMID:11104723 PMID:12953273 PMID:16127145 GO_REF:0000033 GO_REF:0000096 GO_REF:0000107 GO_REF:0000119 RGD:2303089 RGD:2303093 RGD:2303114 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 enables ISO
IEA		 RGD
InterPro
GO_Central		 PMID:9916893 GO_REF:0000002 GO_REF:0000096 RGD:69987 NCBI chr 1:83,094,487...83,096,888
Ensembl chr 1:83,094,487...83,096,888 		JBrowse link
G Ccl21a C-C motif chemokine ligand 21 (serine) enables IDA
ISO
IMP
IBA		 (PMID:12200351)
(PMID:27400149)		 BHF-UCL
GO_Central		 PMID:12200351 PMID:27400149 GO_REF:0000033 GO_REF:0000119 NCBI chr 4:42,772,860...42,773,991
Ensembl chr 4:42,772,860...42,773,993 		JBrowse link
G Ccl21b C-C motif chemokine ligand 21B (leucine) enables ISO
IBA		 (PMID:9300671) MGI
GO_Central		 PMID:9300671 GO_REF:0000033 GO_REF:0000119 NCBI chr 4:42,173,120...42,256,825
Ensembl chr 4:42,255,693...42,256,825 		JBrowse link
G Ccl21d C-C motif chemokine ligand 21D enables ISO
IEA
IBA		 GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000119 NCBI chr 4:41,896,187...41,904,743
Ensembl chr 4:41,903,610...41,904,743 		JBrowse link
G Ccl21e C-C motif chemokine ligand 21E enables ISO GO_Central GO_REF:0000119 NCBI chr 4:42,612,123...42,613,253
Ensembl chr 4:42,612,121...42,613,253 		JBrowse link
G Ccl21f C-C motif chemokine ligand 21F enables ISO GO_Central GO_REF:0000119 NCBI chr 4:42,114,787...42,115,917
Ensembl chr 4:42,114,817...42,115,917 		JBrowse link
G Ccl22 C-C motif chemokine ligand 22 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 8:95,472,312...95,478,016
Ensembl chr 8:95,472,218...95,478,327 		JBrowse link
G Ccl24 C-C motif chemokine ligand 24 enables ISO
IEA
IBA		 GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000119 NCBI chr 5:135,598,789...135,601,977
Ensembl chr 5:135,598,791...135,601,903 		JBrowse link
G Ccl25 C-C motif chemokine ligand 25 enables IDA
ISO
IBA		 (PMID:10623805) MGI
GO_Central		 PMID:10623805 GO_REF:0000033 GO_REF:0000119 NCBI chr 8:4,375,207...4,410,020
Ensembl chr 8:4,375,210...4,410,020 		JBrowse link
G Ccl26 C-C motif chemokine ligand 26 enables ISO
IBA		 GO_Central GO_REF:0000033 GO_REF:0000119 NCBI chr 5:135,589,302...135,592,423
Ensembl chr 5:135,589,302...135,592,423 		JBrowse link
G Ccl27a C-C motif chemokine ligand 27A enables IDA
IEA
IBA		 (PMID:12538707) UniProt
InterPro
GO_Central		 PMID:12538707 GO_REF:0000002 GO_REF:0000033 NCBI chr 4:41,769,467...41,774,251
Ensembl chr 4:41,769,467...41,774,247 		JBrowse link
G Ccl28 C-C motif chemokine ligand 28 enables ISS
IDA
ISO
IBA		 (PMID:10781587)
(PMID:12538707)		 MGI
UniProt
GO_Central		 PMID:10781587 PMID:12538707 GO_REF:0000033 GO_REF:0000119 NCBI chr13:120,085,355...120,115,895
Ensembl chr13:120,085,355...120,115,895 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 enables ISO
IDA
IBA		 (PMID:7594543) RGD
MGI
GO_Central		 PMID:7594543 PMID:10466578 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 RGD:2303107 NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 enables ISO
IEA
IBA		 RGD
InterPro
GO_Central		 PMID:10679105 GO_REF:0000002 GO_REF:0000033 GO_REF:0000096 RGD:68880 NCBI chr11:83,553,410...83,555,509
Ensembl chr11:83,553,410...83,555,509 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 enables ISO
ISS
IBA		 RGD
GO_Central
BHF-UCL		 PMID:11069838 PMID:11104723 GO_REF:0000024 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 RGD:2303112 RGD:2303114 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344 		JBrowse link
G Ccl6 C-C motif chemokine ligand 6 enables ISO
IEA
IBA		 GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 NCBI chr11:83,478,712...83,483,913
Ensembl chr11:83,478,708...83,483,913 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 enables ISO
IEA
IBA		 GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000119 NCBI chr11:81,936,538...81,938,351
Ensembl chr11:81,936,538...81,938,351 		JBrowse link
G Ccl8 C-C motif chemokine ligand 8 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr11:82,006,011...82,007,625
Ensembl chr11:82,006,011...82,007,625 		JBrowse link
G Ccl9 C-C motif chemokine ligand 9 enables ISO
IEA
IBA		 GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000119 NCBI chr11:83,463,743...83,469,462
Ensembl chr11:83,463,745...83,469,462 		JBrowse link
G Cklf chemokine-like factor enables ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 8:104,977,493...104,992,642
Ensembl chr 8:104,977,493...104,991,570 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 enables ISO
IBA		 RGD
GO_Central		 PMID:9724801 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 RGD:727628 NCBI chr 8:95,498,808...95,509,055
Ensembl chr 8:95,498,637...95,509,055 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 enables ISO
IEA		 RGD
InterPro
GO_Central		 PMID:10975996 GO_REF:0000002 GO_REF:0000096 RGD:5135014 NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 enables ISO
ISS
IBA		 RGD
GO_Central
UniProt		 PMID:9288136 GO_REF:0000024 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 RGD:2311389 NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748 		JBrowse link
G Cxcl11 chemokine (C-X-C motif) ligand 11 enables ISO
TAS
ISS		 (PMID:10828609) RGD
MGI
UniProt
GO_Central		 PMID:10828609 PMID:15322564 GO_REF:0000024 GO_REF:0000096 GO_REF:0000119 RGD:1302904 NCBI chr 5:92,507,403...92,511,155
Ensembl chr 5:92,507,403...92,513,344 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 enables IDA
ISO
IBA		 (PMID:12183377) MGI
GO_Central		 PMID:12183377 GO_REF:0000033 GO_REF:0000119 NCBI chr 6:117,145,496...117,158,329
Ensembl chr 6:117,145,496...117,158,328 		JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 enables IDA
ISO
IBA		 (PMID:15972452) BHF-UCL
GO_Central		 PMID:15972452 GO_REF:0000033 GO_REF:0000119 NCBI chr 5:96,104,785...96,108,927
Ensembl chr 5:96,104,810...96,108,927 		JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 enables IEA InterPro GO_REF:0000002 NCBI chr13:56,436,456...56,444,624
Ensembl chr13:56,436,456...56,444,364 		JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 enables IDA
IBA		 (PMID:10228029), (PMID:10714680) MGI
GO_Central		 PMID:10228029 PMID:10714680 GO_REF:0000033 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926 		JBrowse link
G Cxcl16 C-X-C motif chemokine ligand 16 enables IDA
IBA
ISO		 (PMID:11017100) MGI
GO_Central		 PMID:11017100 GO_REF:0000033 GO_REF:0000119 NCBI chr11:70,345,215...70,350,810
Ensembl chr11:70,344,809...70,350,810 		JBrowse link
G Cxcl17 C-X-C motif chemokine ligand 17 enables ISO (PMID:25411203) MGI PMID:25411203 NCBI chr 7:25,099,478...25,112,311
Ensembl chr 7:25,099,478...25,112,311 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 enables ISO
IEA		 RGD
GO_Central
Ensembl		 PMID:10975996 GO_REF:0000096 GO_REF:0000107 RGD:5135014 NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 enables ISO
IDA		 (PMID:14764687) RGD
UniProt
GO_Central		 PMID:10975996 PMID:14764687 GO_REF:0000096 RGD:5135014 NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459 		JBrowse link
G Cxcl5 C-X-C motif chemokine ligand 5 enables ISO
IEA
IBA		 RGD
GO_Central
Ensembl		 PMID:12468547 GO_REF:0000033 GO_REF:0000096 GO_REF:0000107 GO_REF:0000119 RGD:629532 NCBI chr 5:90,907,157...90,909,484
Ensembl chr 5:90,907,219...90,909,483 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 enables ISO
ISS
IBA		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr 5:92,469,190...92,475,938
Ensembl chr 5:92,469,206...92,475,938 		JBrowse link
G Gpr15lg G protein coupled receptor 15 ligand enables IDA
ISO		 (PMID:28900043) UniProt
GO_Central		 PMID:28900043 GO_REF:0000119 NCBI chr14:36,824,097...36,832,058
Ensembl chr14:36,824,097...36,835,979 		JBrowse link
G Pf4 platelet factor 4 enables IEA
ISO
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000119 NCBI chr 5:90,920,362...90,921,242
Ensembl chr 5:90,920,294...90,921,242 		JBrowse link
G Ppbp pro-platelet basic protein enables IDA
IBA		 (PMID:23550035) MGI
GO_Central		 PMID:23550035 GO_REF:0000033 NCBI chr 5:90,916,377...90,917,922
Ensembl chr 5:90,916,377...90,917,922 		JBrowse link
G Xcl1 chemokine (C motif) ligand 1 enables IDA
ISO
IBA		 (PMID:7973732), (PMID:9973465) BHF-UCL
GO_Central		 PMID:7973732 PMID:9973465 GO_REF:0000033 GO_REF:0000119 NCBI chr 1:164,759,216...164,763,094
Ensembl chr 1:164,759,213...164,763,096 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 28792
    binding 17604
      protein binding 15105
        signaling receptor binding 1702
          receptor ligand activity 582
            cytokine activity 240
              chemokine activity 49
paths to the root