Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:chemokine activity
go back to main search page
Accession:GO:0008009 term browser browse the term
Definition:The function of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.


show annotations for term's descendants           Sort by:
chemokine activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C5 complement C5 enables TAS (PMID:10820279) PINC PMID:10820279 NCBI chr 9:120,952,335...121,074,865
Ensembl chr 9:120,932,987...121,075,195 		JBrowse link
G CCL1 C-C motif chemokine ligand 1 enables TAS
IBA
IEA
IDA		 (PMID:9417093)
(PMID:1557400)		 PINC
GO_Central
InterPro
CAFA		 PMID:1557400 PMID:9417093 GO_REF:0000002 GO_REF:0000033 NCBI chr17:34,360,328...34,363,233
Ensembl chr17:34,360,328...34,363,233 		JBrowse link
G CCL11 C-C motif chemokine ligand 11 enables ISO
IBA
IEA
IDA		 (PMID:10072545) RGD
GO_Central
Ensembl
UniProt
InterPro		 PMID:9458816 PMID:10072545 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 RGD:69985 NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334 		JBrowse link
G CCL13 C-C motif chemokine ligand 13 enables IEA
IBA
TAS
IDA		 (PMID:9558100)
(PMID:10072545)		 InterPro
GO_Central
PINC
UniProt		 PMID:9558100 PMID:10072545 GO_REF:0000002 GO_REF:0000033 NCBI chr17:34,356,480...34,358,610
Ensembl chr17:34,356,480...34,358,610 		JBrowse link
G CCL14 C-C motif chemokine ligand 14 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr17:35,983,288...35,986,729
Ensembl chr17:35,983,288...35,987,004 		JBrowse link
G CCL15 C-C motif chemokine ligand 15 enables IEA
IBA
TAS		 (PMID:9346309) InterPro
GO_Central
PINC		 PMID:9346309 GO_REF:0000002 GO_REF:0000033 NCBI chr17:35,997,582...36,001,553
Ensembl chr17:35,996,440...36,001,553 		JBrowse link
G CCL15-CCL14 CCL15-CCL14 readthrough (NMD candidate) enables IEA
ISO		 InterPro
RGD		 PMID:16087246 GO_REF:0000002 RGD:2303127 NCBI chr17:35,983,656...36,002,038 JBrowse link
G CCL16 C-C motif chemokine ligand 16 enables TAS
IBA
IEA		 (PMID:9642106) PINC
GO_Central
InterPro		 PMID:9642106 GO_REF:0000002 GO_REF:0000033 NCBI chr17:35,976,499...35,981,497
Ensembl chr17:35,976,493...35,981,497 		JBrowse link
G CCL17 C-C motif chemokine ligand 17 enables TAS
IBA
IEA		 (PMID:9743322) PINC
GO_Central
InterPro		 PMID:9743322 GO_REF:0000002 GO_REF:0000033 NCBI chr16:57,396,093...57,416,063
Ensembl chr16:57,404,767...57,416,063 		JBrowse link
G CCL18 C-C motif chemokine ligand 18 enables IEA
IBA
TAS		 (PMID:9192897) InterPro
GO_Central
PINC		 PMID:9192897 GO_REF:0000002 GO_REF:0000033 NCBI chr17:36,064,272...36,072,032
Ensembl chr17:36,064,272...36,072,032 		JBrowse link
G CCL19 C-C motif chemokine ligand 19 enables IEA
IBA
IDA		 (PMID:15778365) InterPro
GO_Central
BHF-UCL		 PMID:15778365 GO_REF:0000002 GO_REF:0000033 NCBI chr 9:34,689,570...34,691,276
Ensembl chr 9:34,689,570...34,691,276 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 enables ISO
IBA
TAS
IEA		 (PMID:10623817) RGD
GO_Central
PINC
InterPro		 PMID:10623817 PMID:11104723 PMID:12953273 PMID:16127145 GO_REF:0000002 GO_REF:0000033 RGD:2303089 RGD:2303093 RGD:2303114 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL20 C-C motif chemokine ligand 20 enables ISO
IBA
TAS
IEA		 (PMID:10438902) RGD
GO_Central
PINC
InterPro		 PMID:9916893 PMID:10438902 GO_REF:0000002 GO_REF:0000033 RGD:69987 NCBI chr 2:227,813,842...227,817,556
Ensembl chr 2:227,805,739...227,817,564 		JBrowse link
G CCL21 C-C motif chemokine ligand 21 enables ISS
IBA
IEA
IDA		 (PMID:15778365), (PMID:18308860) BHF-UCL
GO_Central
InterPro
UniProt		 PMID:15778365 PMID:18308860 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 NCBI chr 9:34,709,005...34,710,136
Ensembl chr 9:34,709,005...34,710,136 		JBrowse link
G CCL22 C-C motif chemokine ligand 22 enables TAS
IBA
IEA		 (PMID:10861057) PINC
GO_Central
InterPro		 PMID:10861057 GO_REF:0000002 GO_REF:0000033 NCBI chr16:57,357,909...57,366,189
Ensembl chr16:57,358,783...57,366,189 		JBrowse link
G CCL23 C-C motif chemokine ligand 23 enables IDA
IBA
TAS
IEA		 (PMID:10660125)
(PMID:9886417)		 UniProt
GO_Central
PINC
InterPro		 PMID:9886417 PMID:10660125 GO_REF:0000002 GO_REF:0000033 NCBI chr17:36,013,058...36,017,972
Ensembl chr17:36,013,056...36,017,972 		JBrowse link
G CCL24 C-C motif chemokine ligand 24 enables TAS
IBA
IDA
IEA		 (PMID:9104803)
(PMID:10072545)		 PINC
GO_Central
UniProt
InterPro		 PMID:9104803 PMID:10072545 GO_REF:0000002 GO_REF:0000033 NCBI chr 7:75,810,825...75,823,372
Ensembl chr 7:75,810,825...75,823,356 		JBrowse link
G CCL25 C-C motif chemokine ligand 25 enables TAS
IBA
IEA
IDA		 (PMID:10640743)
(PMID:18308860)		 PINC
GO_Central
InterPro
UniProt		 PMID:10640743 PMID:18308860 GO_REF:0000002 GO_REF:0000033 NCBI chr19:8,052,341...8,062,650
Ensembl chr19:8,052,318...8,062,660 		JBrowse link
G CCL26 C-C motif chemokine ligand 26 enables IEA
IBA
IDA
TAS		 (PMID:10373330) InterPro
GO_Central
CAFA
PINC		 PMID:10373330 GO_REF:0000002 GO_REF:0000033 NCBI chr 7:75,769,524...75,791,597
Ensembl chr 7:75,769,533...75,789,896 		JBrowse link
G CCL27 C-C motif chemokine ligand 27 enables IEA
IBA
TAS		 (PMID:10588729) InterPro
GO_Central
PINC		 PMID:10588729 GO_REF:0000002 GO_REF:0000033 NCBI chr 9:34,661,890...34,662,657
Ensembl chr 9:34,661,880...34,664,048 		JBrowse link
G CCL28 C-C motif chemokine ligand 28 enables IEA
IBA
IDA
TAS		 (PMID:18308860)
(PMID:10781587)		 InterPro
GO_Central
UniProt		 PMID:10781587 PMID:18308860 GO_REF:0000002 GO_REF:0000033 NCBI chr 5:43,356,975...43,412,391
Ensembl chr 5:43,376,645...43,412,391 		JBrowse link
G CCL3 C-C motif chemokine ligand 3 enables ISO
IBA
IEA
IDA		 (PMID:10072545), (PMID:10660125) RGD
GO_Central
InterPro
UniProt		 PMID:10072545 PMID:10466578 PMID:10660125 GO_REF:0000002 GO_REF:0000033 RGD:2303107 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169 		JBrowse link
G CCL3L1 C-C motif chemokine ligand 3 like 1 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 Ensembl chr17:36,194,869...36,196,758 JBrowse link
G CCL3L3 C-C motif chemokine ligand 3 like 3 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr17:36,194,869...36,196,758
Ensembl chr17:36,194,869...36,196,758 		JBrowse link
G CCL4 C-C motif chemokine ligand 4 enables ISO
IBA
IEA
TAS		 (PMID:10929056) RGD
GO_Central
InterPro
PINC		 PMID:10679105 PMID:10929056 GO_REF:0000002 GO_REF:0000033 RGD:68880 NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621 		JBrowse link
G CCL4L1 C-C motif chemokine ligand 4 like 1 enables IEA
IBA
TAS		 (PMID:10929056) InterPro
GO_Central
PINC		 PMID:10929056 GO_REF:0000002 GO_REF:0000033 Ensembl chr17:36,210,924...36,212,878 JBrowse link
G CCL4L2 C-C motif chemokine ligand 4 like 2 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr17:36,211,063...36,212,873
Ensembl chr17:36,210,924...36,212,878 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 enables ISO
IDA
IBA
NAS
IEA		 (PMID:1699135), (PMID:29772059)
(PMID:7524281)		 RGD
BHF-UCL
GO_Central
UniProt
InterPro		 PMID:1699135 PMID:7524281 PMID:11069838 PMID:11104723 PMID:29772059 GO_REF:0000002 GO_REF:0000033 RGD:2303112 RGD:2303114 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CCL7 C-C motif chemokine ligand 7 enables IEA
IBA
IDA
TAS		 (PMID:10072545)
(PMID:10770925)		 InterPro
GO_Central
UniProt
PINC		 PMID:10072545 PMID:10770925 GO_REF:0000002 GO_REF:0000033 NCBI chr17:34,270,221...34,272,242
Ensembl chr17:34,270,221...34,272,242 		JBrowse link
G CCL8 C-C motif chemokine ligand 8 enables TAS
IBA
IEA		 (PMID:9468473) PINC
GO_Central
InterPro		 PMID:9468473 GO_REF:0000002 GO_REF:0000033 NCBI chr17:34,319,435...34,321,402
Ensembl chr17:34,319,435...34,321,402 		JBrowse link
G CKLF chemokine like factor enables IDA (PMID:11415443) UniProt PMID:11415443 NCBI chr16:66,552,563...66,566,287
Ensembl chr16:66,552,563...66,566,251 		JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 enables ISO
IBA
IEA
TAS
IDA
IGI		 (PMID:12714508), (PMID:24352739)
(PMID:21829356)
(PMID:10415068)		 RGD
GO_Central
InterPro
ARUK-UCL
UniProt		 PMID:9724801 PMID:10415068 PMID:12714508 PMID:21829356 PMID:24352739 GO_REF:0000002 GO_REF:0000033 RGD:727628 NCBI chr16:57,372,490...57,385,044
Ensembl chr16:57,372,477...57,385,044 		JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 enables ISO
IBA
IEA
TAS		 (PMID:10820279) RGD
GO_Central
InterPro
PINC		 PMID:10820279 PMID:10975996 GO_REF:0000002 GO_REF:0000033 RGD:5135014 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 enables ISO
IBA
IEA
IDA
TAS		 (PMID:12782716)
(PMID:10903763)		 RGD
GO_Central
InterPro
UniProt
PINC
Ensembl		 PMID:9288136 PMID:10903763 PMID:12782716 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 RGD:2311389 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497 		JBrowse link
G CXCL11 C-X-C motif chemokine ligand 11 enables ISO
IBA
IEA
TAS
IDA		 (PMID:10233762)
(PMID:12782716)		 RGD
GO_Central
InterPro
PINC
UniProt
Ensembl		 PMID:10233762 PMID:12782716 PMID:15322564 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 RGD:1302904 NCBI chr 4:76,033,682...76,036,070
Ensembl chr 4:76,033,682...76,041,415 		JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 enables TAS
IEA
IMP
IDA		 (PMID:10772939), (PMID:12782716)
(PMID:27400149)
(PMID:18308860)		 UniProt
InterPro
BHF-UCL		 PMID:10772939 PMID:12782716 PMID:18308860 PMID:27400149 GO_REF:0000002 NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493 		JBrowse link
G CXCL13 C-X-C motif chemokine ligand 13 enables IDA
IBA
IEA		 (PMID:11554781) BHF-UCL
GO_Central
InterPro		 PMID:11554781 GO_REF:0000002 GO_REF:0000033 NCBI chr 4:77,511,753...77,611,834
Ensembl chr 4:77,511,753...77,611,834 		JBrowse link
G CXCL14 C-X-C motif chemokine ligand 14 enables TAS
IEA		 (PMID:10049774) PINC
InterPro		 PMID:10049774 GO_REF:0000002 NCBI chr 5:135,570,679...135,578,991
Ensembl chr 5:135,570,679...135,579,279 		JBrowse link
G CXCL16 C-X-C motif chemokine ligand 16 enables IDA
IBA
ISS
IEA		 (PMID:18373975) BHF-UCL
GO_Central
UniProt
InterPro		 PMID:18373975 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 NCBI chr17:4,733,533...4,739,928
Ensembl chr17:4,733,533...4,739,928 		JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 enables ISO
IBA
IEA
TAS		 (PMID:9873037) RGD
GO_Central
InterPro
PINC		 PMID:9873037 PMID:10975996 GO_REF:0000002 GO_REF:0000033 RGD:5135014 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196 		JBrowse link
G CXCL3 C-X-C motif chemokine ligand 3 enables ISS
IBA
IEA		 UniProt
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 NCBI chr 4:74,036,589...74,038,689
Ensembl chr 4:74,036,589...74,038,807 		JBrowse link
G CXCL5 C-X-C motif chemokine ligand 5 enables TAS
IBA
IEA		 (PMID:10820279) PINC
GO_Central
InterPro		 PMID:10820279 GO_REF:0000002 GO_REF:0000033 NCBI chr 4:73,995,642...73,998,677
Ensembl chr 4:73,995,642...73,998,677 		JBrowse link
G CXCL6 C-X-C motif chemokine ligand 6 enables ISO
IBA
IEA
IDA		 (PMID:8399143) RGD
GO_Central
InterPro
UniProt		 PMID:8399143 PMID:12468547 GO_REF:0000002 GO_REF:0000033 RGD:629532 NCBI chr 4:73,836,678...73,838,760
Ensembl chr 4:73,836,640...73,849,064 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 enables TAS
IBA
IEA
IDA		 (PMID:10881932), (PMID:12782716)
(PMID:8399143)		 PINC
GO_Central
InterPro
UniProt		 PMID:8399143 PMID:10881932 PMID:12782716 GO_REF:0000002 GO_REF:0000033 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CXCL9 C-X-C motif chemokine ligand 9 enables IDA
IBA
IEA
TAS		 (PMID:12782716)
(PMID:10903763)		 UniProt
GO_Central
InterPro
PINC		 PMID:10903763 PMID:12782716 GO_REF:0000002 GO_REF:0000033 NCBI chr 4:76,001,275...76,007,509
Ensembl chr 4:76,001,275...76,007,509 		JBrowse link
G GPR15LG G protein-coupled receptor 15 ligand enables IEA
IDA		 (PMID:28936214) Ensembl
UniProt		 PMID:28936214 GO_REF:0000107 NCBI chr10:84,173,801...84,185,294
Ensembl chr10:84,173,801...84,185,294 		JBrowse link
G PF4 platelet factor 4 enables TAS
IDA
IBA
IEA		 (PMID:12466273)
(PMID:29930254)		 UniProt
GO_Central
InterPro		 PMID:12466273 PMID:29930254 GO_REF:0000002 GO_REF:0000033 NCBI chr 4:73,980,811...73,982,124
Ensembl chr 4:73,980,811...73,982,027 		JBrowse link
G PF4V1 platelet factor 4 variant 1 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 4:73,853,296...73,854,483
Ensembl chr 4:73,853,296...73,854,483 		JBrowse link
G PPBP pro-platelet basic protein enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 4:73,986,439...73,988,190
Ensembl chr 4:73,986,439...73,988,190 		JBrowse link
G XCL1 X-C motif chemokine ligand 1 enables IEA
IBA
IDA		 (PMID:7602097) InterPro
GO_Central
BHF-UCL		 PMID:7602097 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:168,576,605...168,582,069
Ensembl chr 1:168,576,605...168,582,069 		JBrowse link
G XCL2 X-C motif chemokine ligand 2 enables TAS
IBA
IEA		 (PMID:7875320) PINC
GO_Central
InterPro		 PMID:7875320 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:168,540,768...168,543,997
Ensembl chr 1:168,540,768...168,543,997 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19488
    binding 17886
      protein binding 15414
        signaling receptor binding 1700
          receptor ligand activity 542
            cytokine activity 243
              chemokine activity 51
paths to the root