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ONTOLOGY REPORT - ANNOTATIONS

Term:carboxypeptidase activity
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Accession:GO:0004180 term browser browse the term
Definition:Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain.
Synonyms:xref: RHEA:28783;   Reactome:R-HSA-9753632 "CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly";   reactome:R-HSA-1247910 "CNDP2:2Mn2+ dimer hydrolyses CysGly"


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carboxypeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Ace2 angiotensin converting enzyme 2 enables
NOT|enables		 ISO
IEA
IDA		 (PMID:10924499), (PMID:10969042), (PMID:15283675), (PMID:15380922), (PMID:18258853)
GO_REF:0000107
PMID:22595130
(PMID:33077916)		 RGD
Ensembl		 PMID:10924499 PMID:10969042 PMID:15283675 PMID:15380922 PMID:18258853 More... GO_REF:0000107, RGD:9685456 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Ace3 angiotensin I converting enzyme (peptidyl-dipeptidase A) 3 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:90,933,359...90,949,035
Ensembl chr10:90,935,088...90,948,782 		JBrowse link
G Aebp1 AE binding protein 1 enables ISO (PMID:7477299) RGD PMID:7477299 NCBI chr14:80,738,800...80,748,878
Ensembl chr14:80,738,892...80,748,877 		JBrowse link
G Cndp1 carnosine dipeptidase 1 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr18:77,984,886...78,030,837
Ensembl chr18:77,984,907...78,007,765 		JBrowse link
G Cndp2 carnosine dipeptidase 2 enables IEA GO_REF:0000116 RHEA GO_REF:0000116 NCBI chr18:78,039,924...78,057,030
Ensembl chr18:78,039,932...78,056,922 		JBrowse link
G Cpa2 carboxypeptidase A2 enables ISO (PMID:2920728) RGD PMID:2920728 NCBI chr 4:59,160,357...59,183,677
Ensembl chr 4:59,160,357...59,183,674 		JBrowse link
G Cpb1 carboxypeptidase B1 enables IDA
ISO		 (PMID:1370825) RGD PMID:1370825 PMID:16522183 RGD:2303359 NCBI chr 2:102,755,241...102,785,628
Ensembl chr 2:102,755,241...102,785,628 		JBrowse link
G Cpb2 carboxypeptidase B2 enables IDA
ISO		 (PMID:10739389) RGD PMID:10739389 PMID:11021404 RGD:625371 NCBI chr15:50,557,722...50,606,569
Ensembl chr15:50,557,717...50,606,556 		JBrowse link
G Cpe carboxypeptidase E enables IDA
ISO		 MGI:1856395 (PMID:7663508) RGD PMID:7663508 PMID:2822027 RGD:1626225 NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233 		JBrowse link
G Cpn1 carboxypeptidase N subunit 1 enables IDA
ISO
IMP		 (PMID:10878383) RGD PMID:10878383 PMID:11021404 PMID:11299220 RGD:625371, RGD:7401264 NCBI chr 1:242,844,575...242,873,465
Ensembl chr 1:242,844,212...242,873,465 		JBrowse link
G Cpq carboxypeptidase Q enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:64,264,025...64,830,867
Ensembl chr 7:64,264,081...64,724,546 		JBrowse link
G Cpxm1 carboxypeptidase X (M14 family), member 1 NOT|enables ISO (PMID:10073577) RGD PMID:10073577 NCBI chr 3:117,588,532...117,595,330
Ensembl chr 3:117,588,532...117,595,330 		JBrowse link
G Cpxm2 carboxypeptidase X (M14 family), member 2 NOT|enables ISO (PMID:9809751) RGD PMID:9809751 NCBI chr 1:186,836,797...186,947,222
Ensembl chr 1:186,836,797...186,947,220 		JBrowse link
G Ctsz cathepsin Z enables ISO
IEA		 (PMID:19433310)
GO_REF:0000107		 RGD
Ensembl		 PMID:19433310 GO_REF:0000107 NCBI chr 3:163,224,875...163,235,645
Ensembl chr 3:163,224,875...163,235,645 		JBrowse link
G Folh1 folate hydrolase 1 enables IEA
ISO
IBA		 GO_REF:0000107
(PMID:21908619)
GO_REF:0000033		 Ensembl
RGD
GO_Central		 PMID:21908619 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:140,428,101...140,501,563
Ensembl chr 1:140,428,101...140,501,379 		JBrowse link
G Lap3 leucine aminopeptidase 3 enables IEA GO_REF:0000116 RHEA GO_REF:0000116 NCBI chr14:65,608,375...65,627,359
Ensembl chr14:65,608,376...65,627,359 		JBrowse link
G Matcap2 microtubule associated tyrosine carboxypeptidase 2 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 8:20,921,637...20,971,076
Ensembl chr 8:20,921,244...20,971,069 		JBrowse link
G Naalad2 N-acetylated alpha-linked acidic dipeptidase 2 enables IBA
ISO		 GO_REF:0000033
(PMID:21908619)		 GO_Central
RGD		 PMID:21908619 GO_REF:0000033 NCBI chr 8:15,406,119...15,479,714
Ensembl chr 8:15,407,043...15,479,714 		JBrowse link
G Naaladl1 N-acetylated alpha-linked acidic dipeptidase-like 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:203,400,632...203,414,195
Ensembl chr 1:203,400,631...203,414,195 		JBrowse link
G Pm20d2 peptidase M20 domain containing 2 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:47,566,059...47,586,334
Ensembl chr 5:47,566,072...47,586,212 		JBrowse link
cysteine-type carboxypeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsl cathepsin L enables ISO (PMID:11023992) RGD PMID:11023992 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548 		JBrowse link
G Ctsz cathepsin Z enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr 3:163,224,875...163,235,645
Ensembl chr 3:163,224,875...163,235,645 		JBrowse link
G Mindy1 MINDY lysine 48 deubiquitinase 1 enables ISO
IBA		 (PMID:27292798)
GO_REF:0000033		 RGD
GO_Central		 PMID:27292798 GO_REF:0000033 NCBI chr 2:182,859,977...182,873,000
Ensembl chr 2:182,860,472...182,873,015 		JBrowse link
G Mindy2 MINDY lysine 48 deubiquitinase 2 enables ISO
IBA		 (PMID:27292798)
GO_REF:0000033		 RGD
GO_Central		 PMID:27292798 GO_REF:0000033 NCBI chr 8:71,268,274...71,327,698
Ensembl chr 8:71,256,447...71,328,453 		JBrowse link
metallocarboxypeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme enables ISO (PMID:18158355), (PMID:27649628) RGD PMID:18158355 PMID:27649628 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Ace2 angiotensin converting enzyme 2 enables ISO UniProtKB:Q9BYF1 (PMID:18263657), (PMID:20357030), (PMID:23462816) RGD PMID:18263657 PMID:20357030 PMID:23462816 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Aebp1 AE binding protein 1 enables IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr14:80,738,800...80,748,878
Ensembl chr14:80,738,892...80,748,877 		JBrowse link
G Agbl1 AGBL carboxypeptidase 1 enables ISO
IBA		 (PMID:21074048), (PMID:25103237)
GO_REF:0000033		 RGD
GO_Central		 PMID:21074048 PMID:25103237 GO_REF:0000033 NCBI chr 1:130,043,914...130,950,739
Ensembl chr 1:130,043,970...130,951,638 		JBrowse link
G Agbl2 AGBL carboxypeptidase 2 enables ISO
IBA		 (PMID:25103237)
GO_REF:0000033		 RGD
GO_Central		 PMID:25103237 GO_REF:0000033 NCBI chr 3:76,764,893...76,800,071
Ensembl chr 3:76,764,238...76,800,214 		JBrowse link
G Agbl3 AGBL carboxypeptidase 3 enables ISO
IBA		 (PMID:17244817)
GO_REF:0000033
(PMID:25103237)		 RGD
GO_Central		 PMID:17244817 PMID:25103237 GO_REF:0000033 NCBI chr 4:63,448,789...63,535,538
Ensembl chr 4:63,453,940...63,531,188 		JBrowse link
G Agbl4 AGBL carboxypeptidase 4 enables ISO (PMID:21074048), (PMID:25103237), (PMID:26829768), (PMID:29593216) RGD PMID:21074048 PMID:25103237 PMID:26829768 PMID:29593216 NCBI chr 5:125,254,963...126,534,367
Ensembl chr 5:125,254,956...126,534,367 		JBrowse link
G Agbl5 AGBL carboxypeptidase 5 enables ISS
IBA
ISO
IEA		 GO_REF:0000024
GO_REF:0000033
(PMID:20519502), (PMID:21074048), (PMID:24022482), (PMID:25103237), (PMID:26829768)
GO_REF:0000117		 UniProt
GO_Central
RGD		 PMID:20519502 PMID:21074048 PMID:24022482 PMID:25103237 PMID:26829768 GO_REF:0000024 GO_REF:0000033 GO_REF:0000117 NCBI chr 6:25,472,333...25,492,173
Ensembl chr 6:25,472,333...25,490,738 		JBrowse link
G Agtpbp1 ATP/GTP binding carboxypeptidase 1 enables ISO
IBA		 (PMID:22170066)
GO_REF:0000033
(PMID:21074048), (PMID:22170066), (PMID:25103237), (PMID:29593216), (PMID:30420557)		 RGD
GO_Central		 PMID:21074048 PMID:22170066 PMID:25103237 PMID:29593216 PMID:30420557 GO_REF:0000033 NCBI chr17:5,120,540...5,238,874
Ensembl chr17:5,120,609...5,238,869 		JBrowse link
G Cpa1 carboxypeptidase A1 enables ISS
ISO
IBA		 GO_REF:0000024
(PMID:20385563)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:20385563 GO_REF:0000024 GO_REF:0000033 NCBI chr 4:59,257,417...59,263,544
Ensembl chr 4:59,257,417...59,263,544 		JBrowse link
G Cpa2 carboxypeptidase A2 enables IEA
IBA
ISO
ISS		 GO_REF:0000107
GO_REF:0000033
(PMID:20385563), (PMID:2920728)
GO_REF:0000024
GO_REF:0000002		 Ensembl
GO_Central
RGD
UniProt
InterPro		 PMID:2920728 PMID:20385563 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:59,160,357...59,183,677
Ensembl chr 4:59,160,357...59,183,674 		JBrowse link
G Cpa3 carboxypeptidase A3 enables IEA
IBA
ISO		 GO_REF:0000002
GO_REF:0000033
(PMID:15173164)		 InterPro
GO_Central
RGD		 PMID:15173164 GO_REF:0000002 GO_REF:0000033 NCBI chr 2:102,712,483...102,744,219
Ensembl chr 2:102,712,589...102,744,203 		JBrowse link
G Cpa4 carboxypeptidase A4 enables ISO
IBA		 (PMID:20385563)
GO_REF:0000033		 RGD
GO_Central		 PMID:20385563 GO_REF:0000033 NCBI chr 4:59,188,284...59,212,255
Ensembl chr 4:59,188,284...59,212,255 		JBrowse link
G Cpa5 carboxypeptidase A5 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:59,229,754...59,249,503
Ensembl chr 4:59,230,964...59,249,490 		JBrowse link
G Cpa6 carboxypeptidase A6 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:8,526,708...8,888,492
Ensembl chr 5:8,526,741...8,888,485 		JBrowse link
G Cpb1 carboxypeptidase B1 enables IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 2:102,755,241...102,785,628
Ensembl chr 2:102,755,241...102,785,628 		JBrowse link
G Cpb2 carboxypeptidase B2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:50,557,722...50,606,569
Ensembl chr15:50,557,717...50,606,556 		JBrowse link
G Cpd carboxypeptidase D enables IEA
ISS
IBA		 GO_REF:0000003
GO_REF:0000024
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000003 GO_REF:0000024 GO_REF:0000033 NCBI chr10:61,623,528...61,687,491
Ensembl chr10:61,623,526...61,687,491 		JBrowse link
G Cpe carboxypeptidase E enables IEA
IBA
ISO		 GO_REF:0000003
GO_REF:0000033
MGI:1856395 (PMID:9348219)		 UniProt
GO_Central
RGD		 PMID:9348219 GO_REF:0000003 GO_REF:0000033 NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233 		JBrowse link
G Cpm carboxypeptidase M enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:53,225,647...53,286,220
Ensembl chr 7:53,225,696...53,286,220 		JBrowse link
G Cpn1 carboxypeptidase N subunit 1 enables IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:242,844,575...242,873,465
Ensembl chr 1:242,844,212...242,873,465 		JBrowse link
G Cpo carboxypeptidase O enables ISO (PMID:21921028) RGD PMID:21921028 NCBI chr 9:65,319,996...65,338,250 JBrowse link
G Cpz carboxypeptidase Z enables IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr14:75,223,692...75,246,946
Ensembl chr14:75,223,605...75,246,945 		JBrowse link
G Folh1 folate hydrolase 1 enables ISO (PMID:12949938), (PMID:17241121), (PMID:24863754) RGD PMID:12949938 PMID:17241121 PMID:24863754 NCBI chr 1:140,428,101...140,501,563
Ensembl chr 1:140,428,101...140,501,379 		JBrowse link
G Matcap1 microtubule associated tyrosine carboxypeptidase 1 enables ISS
ISO		 GO_REF:0000024
(PMID:35482892)		 UniProt
RGD		 PMID:35482892 GO_REF:0000024 NCBI chr19:33,158,053...33,166,784
Ensembl chr19:33,158,056...33,166,445 		JBrowse link
G Mme membrane metallo-endopeptidase enables ISO MGI:2137696 (PMID:28559246) RGD PMID:28559246 NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792 		JBrowse link
G Prcp prolylcarboxypeptidase enables ISO (PMID:27649628) RGD PMID:27649628 NCBI chr 1:146,931,487...146,983,891
Ensembl chr 1:146,930,561...146,984,530 		JBrowse link
G Prep prolyl endopeptidase enables ISO (PMID:27649628) RGD PMID:27649628 NCBI chr20:48,556,211...48,653,165
Ensembl chr20:48,556,280...48,654,466 		JBrowse link
G Vash1 vasohibin 1 enables ISO (PMID:29146869), (PMID:31171830), (PMID:31235911)
(PMID:29146868)		 RGD PMID:29146868 PMID:29146869 PMID:31171830 PMID:31235911 NCBI chr 6:106,330,374...106,345,740
Ensembl chr 6:106,329,123...106,345,726 		JBrowse link
G Vash2 vasohibin 2 enables ISO (PMID:29146869), (PMID:31171830), (PMID:31235911)
(PMID:29146868), (PMID:31324789)		 RGD PMID:29146868 PMID:29146869 PMID:31171830 PMID:31235911 PMID:31324789 NCBI chr13:102,529,718...102,561,204
Ensembl chr13:102,529,719...102,560,391 		JBrowse link
serine-type carboxypeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cpvl carboxypeptidase, vitellogenic-like enables IEA
IBA		 GO_REF:0000104
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000104 NCBI chr 4:82,981,421...83,091,730
Ensembl chr 4:82,981,422...83,085,655 		JBrowse link
G Ctsa cathepsin A enables ISO
IBA		 (PMID:12505983), (PMID:1907282)
GO_REF:0000033		 RGD
GO_Central		 PMID:1907282 PMID:12505983 GO_REF:0000033 NCBI chr 3:153,569,106...153,574,983
Ensembl chr 3:153,568,381...153,576,215 		JBrowse link
G Scpep1 serine carboxypeptidase 1 enables TAS
ISO
IBA
IEA		 (PMID:24586188)
GO_REF:0000033
GO_REF:0000104
GO_REF:0000002		 RGD
GO_Central
UniProt
InterPro		 PMID:24586188 PMID:11447226 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104, RGD:70518 NCBI chr10:73,703,275...73,732,892
Ensembl chr10:73,703,278...73,732,850 		JBrowse link
tubulin-tyrosine carboxypeptidase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Matcap1 microtubule associated tyrosine carboxypeptidase 1 enables ISS
ISO
IEA		 GO_REF:0000024
(PMID:35482892)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:35482892 GO_REF:0000024 GO_REF:0000107 NCBI chr19:33,158,053...33,166,784
Ensembl chr19:33,158,056...33,166,445 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20626
    catalytic activity 6028
      catalytic activity, acting on a protein 2508
        peptidase activity 696
          exopeptidase activity 105
            carboxypeptidase activity 48
              cysteine-type carboxypeptidase activity 4
              metallocarboxypeptidase activity + 30
              muramoyltetrapeptide carboxypeptidase activity 0
              serine-type carboxypeptidase activity + 3
paths to the root